LOCUS       NW_017264883            9254 bp    DNA     linear   CON 15-SEP-2023
DEFINITION  Fusarium oxysporum f. sp. lycopersici 4287 supercont2.83 genomic
            scaffold, whole genome shotgun sequence.
ACCESSION   NW_017264883
VERSION     NW_017264883.1
KEYWORDS    WGS; RefSeq.
SOURCE      Fusarium oxysporum f. sp. lycopersici 4287
  ORGANISM  Fusarium oxysporum f. sp. lycopersici 4287
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium; Fusarium oxysporum species complex.
REFERENCE   1  (bases 1 to 9254)
  AUTHORS   Ma,L.J., van der Does,H.C., Borkovich,K.A., Coleman,J.J.,
            Daboussi,M.J., Di Pietro,A., Dufresne,M., Freitag,M., Grabherr,M.,
            Henrissat,B., Houterman,P.M., Kang,S., Shim,W.B., Woloshuk,C.,
            Xie,X., Xu,J.R., Antoniw,J., Baker,S.E., Bluhm,B.H., Breakspear,A.,
            Brown,D.W., Butchko,R.A., Chapman,S., Coulson,R., Coutinho,P.M.,
            Danchin,E.G., Diener,A., Gale,L.R., Gardiner,D.M., Goff,S.,
            Hammond-Kosack,K.E., Hilburn,K., Hua-Van,A., Jonkers,W., Kazan,K.,
            Kodira,C.D., Koehrsen,M., Kumar,L., Lee,Y.H., Li,L., Manners,J.M.,
            Miranda-Saavedra,D., Mukherjee,M., Park,G., Park,J., Park,S.Y.,
            Proctor,R.H., Regev,A., Ruiz-Roldan,M.C., Sain,D., Sakthikumar,S.,
            Sykes,S., Schwartz,D.C., Turgeon,B.G., Wapinski,I., Yoder,O.,
            Young,S., Zeng,Q., Zhou,S., Galagan,J., Cuomo,C.A., Kistler,H.C. and
            Rep,M.
  TITLE     Comparative genomics reveals mobile pathogenicity chromosomes in
            Fusarium
  JOURNAL   Nature 464 (7287), 367-373 (2010)
   PUBMED   20237561
REFERENCE   2  (bases 1 to 9254)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-SEP-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 9254)
  AUTHORS   Birren,B., Lander,E., Galagan,J., Nusbaum,C., Devon,K., Ma,L.-J.,
            Jaffe,D., Butler,J., Alvarez,P., Gnerre,S., Grabherr,M., Kleber,M.,
            Mauceli,E., Brockman,W., MacCallum,I.A., Young,S., LaButti,K.,
            DeCaprio,D., Crawford,M., Koehrsen,M., Engels,R., Montgomery,P.,
            Pearson,M., Howarth,C., Larson,L., White,J., O'Leary,S., Kodira,C.,
            Zeng,Q., Yandava,C., Alvarado,L., Kistler,C., Shim,W.-B., Kang,S.
            and Woloshuk,C.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2007) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider :: INSDC submitter
            Annotation Status   :: Full annotation
            Annotation Pipeline :: Eukaryotic Annotation Propagation Pipeline
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version             :: 8.dev-cf2fc5ee(changed)
            Run date            :: 2025-09-13 06:41:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start         :: 0
            Orig. end           :: 9254
            ##antiSMASH-Data-END##
            PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to DS231778.
            Originally submitted as Fusarium oxysporum f. sp. lycopersici 4286
            Annotation was added to the scaffolds in July 2015.
FEATURES             Location/Qualifiers
     source          1..9254
                     /chromosome="Unknown"
                     /db_xref="taxon:426428"
                     /forma_specialis="lycopersici"
                     /mol_type="genomic DNA"
                     /organism="Fusarium oxysporum f. sp. lycopersici 4287"
                     /strain="4287"
     region          1..9254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..9254
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..9254
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2403:9108](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2404..9108)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="30000"
                     /product="NRPS"
                     /protocluster_number="1"
     mRNA            complement(join(<1107..1308,1539..>1666))
                     /db_xref="GeneID:28963645"
                     /locus_tag="FOXG_22939"
                     /product="uncharacterized protein"
                     /transcript_id="XM_018403363.1"
     gene            complement(<1107..>1666)
                     /db_xref="GeneID:28963645"
                     /locus_tag="FOXG_22939"
     CDS             complement(join(1107..1308,1539..1666))
                     /codon_start=1
                     /db_xref="GeneID:28963645"
                     /locus_tag="FOXG_22939"
                     /product="uncharacterized protein"
                     /protein_id="XP_018258846.1"
                     /transl_table=1
                     /translation="MTGPCLNVTPLTIKNVFPKGEAESLQVGEKARLIQATLAERVPSG
                     TSISKLDISYLPKENVYIDVAPDSLTDTIGFGVRVQGRLMDKEEARNLVERIGKEITAL
                     VQGLE"
     mRNA            complement(join(<2404..3802,3862..6748,6879..8093,
                     8169..>9108))
                     /db_xref="GeneID:28963646"
                     /locus_tag="FOXG_22940"
                     /product="uncharacterized protein"
                     /transcript_id="XM_018403364.1"
     gene            complement(<2404..>9108)
                     /db_xref="GeneID:28963646"
                     /locus_tag="FOXG_22940"
     CDS             complement(join(2404..3802,3862..6748,6879..8093,
                     8169..9108))
                     /NRPS_PKS="Domain: Condensation_DCL (1-281). E-value:
                     5.6e-30. Score: 96.4. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (424-789). E-value: 2.2e-40.
                     Score: 130.4. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (930-993). E-value: 1.4e-12.
                     Score: 39.8. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1036-1322). E-value:
                     1.8e-37. Score: 121.0. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_Condensation_DCL.2"
                     /NRPS_PKS="Domain: PP-binding (1476-1539). E-value:
                     6.8e-14. Score: 43.9. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_PP-binding.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1681-1846). E-value:
                     1.1e-21. Score: 69.2. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_Condensation_DCL.3"
                     /NRPS_PKS="Domain: PP-binding (2015-2077). E-value:
                     2.8e-12. Score: 38.8. Matches aSDomain:
                     nrpspksdomains_FOXG_22940_PP-binding.3"
                     /codon_start=1
                     /db_xref="GeneID:28963646"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /locus_tag="FOXG_22940"
                     /product="uncharacterized protein"
                     /protein_id="XP_018258847.1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-40, bitscore:
                     125.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.3e-36, bitscore:
                     113.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.9e-14, bitscore:
                     39.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MYWSHHFFSLHSDVDIDKLEQAWATVCRGNEALRTCFIPVAALQK
                     PIHGCENDSGILQVILEQHEVDWEYIECKSKSYQQNLRRRIVALQDRHQSSHFQNPPWA
                     ITIMDDFQERTMIFSIHHVLYDGTSLGYIMNDVCCAYGADAPNRPQLRNALSLLLPSKK
                     ASLDAQEFWEQELSDYADFDVPSWPDLSGERTSPERDNIRRFITETVPLSVPTAQLEAK
                     NAELGVLSVASVVQAAFGHVLLSYLGSSGVVFAETLSDRVLDADVDRTIGPFISVVPMP
                     FNSNGTVREVLAEQHRLSTKAKKHRHIHAQVIHLMAASARTIWDTKIDNFGLSVEHPMA
                     LNVFREPDGTVILEASSLNTIMGLKQLAIFTRQIDALVGAMLYNPDVPLKSLPSYIEKG
                     LLSISAPSPSDAVKESANMSPVDWVETTAGQHPEWTAVEETLSITAAGAEQLLMSYGEQ
                     NASANPVAAYLNHCGIKKRAVALCSQQNLASYPVLVGIMKSGNSYLPIDEGLPDDRKAF
                     LIEDGDAPILFTETAFASTFQGAPSECRIVCIDEPSVQQEFLAFSSENSTYVANPEDTA
                     YILYTSGSTGKPKGVMISRANLSSFIESLSELVCRIAPATVELGGKGRWLGQSSRAFDP
                     HIVEMFFPWRHGMATSTDARPLRMDDLRLTLDKLEITHASFIPTLLDQADIHPEHCPSL
                     RLLSVGGRKDLPESLRYMGLFKSSDTPDYALHGQTGELCFTGDLVGKGYLNRPDAKEFV
                     IGPDQEKIYRTGDVGRRMADGSIEYLRRGDDQTKIRGQRLELGEVSEVLRTSSRASIDV
                     VTLIAKHPGLARQQLVSFIARLGSQRFNAKNPLSIIPADIGTLCKGLQDTCRQKLPSYM
                     VPEIVLPVNRIPFAAMSDKVNSKLLQELFASLPLSDVFRGNEAAHDGLNKDRELTANEE
                     AVADAICQTLAIDQSVIYPQTNIFEIGIDSLSAIDLSVRLRHIGLSASVAHVMSNPVVE
                     QLARLPWTTNPPSVVVSSSEVQSRLSNLESQLLESQTPNMNELPVASVRPCLPLQEGLV
                     ARSINSNSGLYVNHIVLKMNPSADPVRLQNAWQDTIKETEILRTAFVPLQSGIVQVVLK
                     PNYSGDWTEGQYDDLEVAMAHFQSRQNVIGRDITNNMMSIPPLRIEHVVTTVSRQPLAL
                     FISIHHGLYDGVSFNMLLQDFAARYLPDMAPPKRGSPEAFIKHVYSQNIERSESYWRLT
                     LAGCRPTTFKKPVSDPTRHVHSTMLWPSLPELESCAARLKSTLSSLAQAVFALTLADSV
                     SASDVTYGVVLSGRVLPVAGANSVLLPCIATIPARLNMENLSSVEDVVKHVHKGNSEAL
                     DYQHNSLRHIQRWIKAEGPIFDCLFSFTKSAPGQSHGLWEGMESSMPSEYPLALEVEAD
                     EKNKRVLLTCGFTSSFGQTDDAQDIMEKLNLILSALVSNPYISLNSLNLSWPSATAIME
                     TKKDWEGRPWSNLEVEICDLVKRFSGLEGQQISRNTSFLSLGLDSVTAIQFSSQLRDAG
                     VSASPAEVMRFSSIGALAHSVFEKTAAEVPSPPRSNYDDDILLDEFTCQVERLSSDDTV
                     ESVFKCSPLQTAMITQTIESKGIVYVHLHIVRLTESTVVDRLKEAYRLMAMAKDILRTS
                     FHPVPELEMDYYWVGTFTATLHLVGRKYLFHRVPTSLRRSCNCEDEENLLVIIMHHALY
                     GGASLPFIFNDLASVYQGISLPMRPPFATAVRSLSQDQTEACQFWTSTFEGYEAKPLPL
                     SSHQQLCSEMFYSEAKVDLDMTEILERCKEMEVTVQSVTNLAYAKVLATLTEKRDVAFG
                     QVLAGCSSLGLEAEHVVGPLFNIVAKRVTLDPKFISNRKKVQMIQKFTTEAQTHEHAPL
                     HEVQKSLRCKGVLSAATLVDTLFVVQKSVRALQDDPMDSKIWMPYVTDDYIPKSEYRMN
                     TEVEQTDKAITVRASCQGEFMAKRDLDRTLKDFSQAFCDIIQHPLRCVTIFPDELQSLP
                     LSFGSPSDSAVSVISTPGPSHEPVIRDILSKVSKVSIEAIQPDTSIFSIGLDSLSAIRV
                     ASMCRAAGFKAGVSDILQGNTLRGTCLRIHDMPQENTSKQSLIKDYSSVKKDVIVQLGM
                     KQNAIEKILPCLSGQMYHLASWLQTGRTLFEPAWPF"
     aSDomain        complement(2614..2799)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_PP-binding.3"
                     /evalue="2.80E-12"
                     /label="FOXG_22940_PP-binding.3"
                     /locus_tag="FOXG_22940"
                     /protein_end="2077"
                     /protein_start="2015"
                     /score="38.8"
                     /tool="antismash"
                     /translation="VIRDILSKVSKVSIEAIQPDTSIFSIGLDSLSAIRVASMCRAAGF
                     KAGVSDILQGNTLRGTC"
     aSModule        complement(2614..3801)
                     /domains="nrpspksdomains_FOXG_22940_Condensation_DCL.3"
                     /domains="nrpspksdomains_FOXG_22940_PP-binding.3"
                     /incomplete
                     /locus_tags="FOXG_22940"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(3307..3801)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_Condensation_DCL.3"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.10E-21"
                     /label="FOXG_22940_Condensation_DCL.3"
                     /locus_tag="FOXG_22940"
                     /protein_end="1846"
                     /protein_start="1681"
                     /score="69.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHALYGG"
                     /tool="antismash"
                     /translation="EDEENLLVIIMHHALYGGASLPFIFNDLASVYQGISLPMRPPFAT
                     AVRSLSQDQTEACQFWTSTFEGYEAKPLPLSSHQQLCSEMFYSEAKVDLDMTEILERCK
                     EMEVTVQSVTNLAYAKVLATLTEKRDVAFGQVLAGCSSLGLEAEHVVGPLFNIVAKRVT
                     LD"
     CDS_motif       complement(3325..3414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0013"
                     /evalue="1.70E-01"
                     /label="C5_DCL_263-294"
                     /locus_tag="FOXG_22940"
                     /protein_end="1840"
                     /protein_start="1810"
                     /score="4.5"
                     /tool="antismash"
                     /translation="DVAFGQVLAGCSSLGLEAEHVVGPLFNIVA"
     CDS_motif       complement(3706..3771)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0012"
                     /evalue="2.70E-02"
                     /label="C3_DCL_135-156"
                     /locus_tag="FOXG_22940"
                     /protein_end="1713"
                     /protein_start="1691"
                     /score="7.3"
                     /tool="antismash"
                     /translation="MHHALYGGASLPFIFNDLASVY"
     CDS_motif       complement(3984..4076)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0011"
                     /evalue="3.20E-01"
                     /label="C2_DCL_024-062"
                     /locus_tag="FOXG_22940"
                     /protein_end="1640"
                     /protein_start="1609"
                     /score="3.4"
                     /tool="antismash"
                     /translation="VRLTESTVVDRLKEAYRLMAMAKDILRTSFH"
     aSDomain        complement(4287..4475)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_PP-binding.2"
                     /evalue="6.80E-14"
                     /label="FOXG_22940_PP-binding.2"
                     /locus_tag="FOXG_22940"
                     /protein_end="1539"
                     /protein_start="1476"
                     /score="43.9"
                     /tool="antismash"
                     /translation="EICDLVKRFSGLEGQQISRNTSFLSLGLDSVTAIQFSSQLRDAGV
                     SASPAEVMRFSSIGALAH"
     aSModule        complement(4287..5795)
                     /domains="nrpspksdomains_FOXG_22940_Condensation_DCL.2"
                     /domains="nrpspksdomains_FOXG_22940_PP-binding.2"
                     /incomplete
                     /locus_tags="FOXG_22940"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4794..4886)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0010"
                     /evalue="1.70E-04"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="FOXG_22940"
                     /protein_end="1370"
                     /protein_start="1339"
                     /score="13.9"
                     /tool="antismash"
                     /translation="SEALDYQHNSLRHIQRWIKAEGPIFDCLFSF"
     aSDomain        complement(4938..5795)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_Condensation_DCL.2"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.80E-37"
                     /label="FOXG_22940_Condensation_DCL.2"
                     /locus_tag="FOXG_22940"
                     /protein_end="1322"
                     /protein_start="1036"
                     /score="121.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHGLYDG"
                     /tool="antismash"
                     /translation="VRPCLPLQEGLVARSINSNSGLYVNHIVLKMNPSADPVRLQNAWQ
                     DTIKETEILRTAFVPLQSGIVQVVLKPNYSGDWTEGQYDDLEVAMAHFQSRQNVIGRDI
                     TNNMMSIPPLRIEHVVTTVSRQPLALFISIHHGLYDGVSFNMLLQDFAARYLPDMAPPK
                     RGSPEAFIKHVYSQNIERSESYWRLTLAGCRPTTFKKPVSDPTRHVHSTMLWPSLPELE
                     SCAARLKSTLSSLAQAVFALTLADSVSASDVTYGVVLSGRVLPVAGANSVLLPCIATIP
                     ARLNM"
     CDS_motif       complement(4947..5042)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0009"
                     /evalue="4.80E-05"
                     /label="C5_DCL_263-294"
                     /locus_tag="FOXG_22940"
                     /protein_end="1319"
                     /protein_start="1287"
                     /score="15.9"
                     /tool="antismash"
                     /translation="DVTYGVVLSGRVLPVAGANSVLLPCIATIPAR"
     CDS_motif       complement(5343..5408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0008"
                     /evalue="4.30E-05"
                     /label="NRPS-E2"
                     /locus_tag="FOXG_22940"
                     /protein_end="1187"
                     /protein_start="1165"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LFISIHHGLYDGVSFNMLLQDF"
     CDS_motif       complement(5619..5735)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0007"
                     /evalue="1.30E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="FOXG_22940"
                     /protein_end="1095"
                     /protein_start="1056"
                     /score="23.9"
                     /tool="antismash"
                     /translation="GLYVNHIVLKMNPSADPVRLQNAWQDTIKETEILRTAFV"
     aSDomain        complement(5925..6113)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_PP-binding.1"
                     /evalue="1.40E-12"
                     /label="FOXG_22940_PP-binding.1"
                     /locus_tag="FOXG_22940"
                     /protein_end="993"
                     /protein_start="930"
                     /score="39.8"
                     /tool="antismash"
                     /translation="AVADAICQTLAIDQSVIYPQTNIFEIGIDSLSAIDLSVRLRHIGL
                     SASVAHVMSNPVVEQLAR"
     aSModule        complement(5925..9105)
                     /complete
                     /domains="nrpspksdomains_FOXG_22940_Condensation_DCL.1"
                     /domains="nrpspksdomains_FOXG_22940_AMP-binding.1"
                     /domains="nrpspksdomains_FOXG_22940_PP-binding.1"
                     /locus_tags="FOXG_22940"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(6510..6572)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0006"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="FOXG_22940"
                     /protein_end="798"
                     /protein_start="777"
                     /score="26.2"
                     /tool="antismash"
                     /translation="YLRRGDDQTKIRGQRLELGEV"
     aSDomain        complement(join(6537..6748,6879..7761))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_AMP-binding.1"
                     /evalue="2.20E-40"
                     /label="FOXG_22940_AMP-binding.1"
                     /locus_tag="FOXG_22940"
                     /protein_end="789"
                     /protein_start="424"
                     /score="130.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ETTAGQHPEWTAVEETLSITAAGAEQLLMSYGEQNASANPVAAYL
                     NHCGIKKRAVALCSQQNLASYPVLVGIMKSGNSYLPIDEGLPDDRKAFLIEDGDAPILF
                     TETAFASTFQGAPSECRIVCIDEPSVQQEFLAFSSENSTYVANPEDTAYILYTSGSTGK
                     PKGVMISRANLSSFIESLSELVCRIAPATVELGGKGRWLGQSSRAFDPHIVEMFFPWRH
                     GMATSTDARPLRMDDLRLTLDKLEITHASFIPTLLDQADIHPEHCPSLRLLSVGGRKDL
                     PESLRYMGLFKSSDTPDYALHGQTGELCFTGDLVGKGYLNRPDAKEFVIGPDQEKIYRT
                     GDVGRRMADGSIEYLRRGDDQTKIR"
     CDS_motif       complement(6657..6725)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0005"
                     /evalue="1.90E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="FOXG_22940"
                     /protein_end="749"
                     /protein_start="726"
                     /score="23.4"
                     /tool="antismash"
                     /translation="GQTGELCFTGDLVGKGYLNRPDA"
     CDS_motif       complement(7252..7308)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0004"
                     /evalue="7.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="FOXG_22940"
                     /protein_end="594"
                     /protein_start="575"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AYILYTSGSTGKPKGVMIS"
     aSDomain        complement(8266..9105)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FOXG_22940_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.60E-30"
                     /label="FOXG_22940_Condensation_DCL.1"
                     /locus_tag="FOXG_22940"
                     /protein_end="281"
                     /protein_start="1"
                     /score="96.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVLYDG"
                     /tool="antismash"
                     /translation="YWSHHFFSLHSDVDIDKLEQAWATVCRGNEALRTCFIPVAALQKP
                     IHGCENDSGILQVILEQHEVDWEYIECKSKSYQQNLRRRIVALQDRHQSSHFQNPPWAI
                     TIMDDFQERTMIFSIHHVLYDGTSLGYIMNDVCCAYGADAPNRPQLRNALSLLLPSKKA
                     SLDAQEFWEQELSDYADFDVPSWPDLSGERTSPERDNIRRFITETVPLSVPTAQLEAKN
                     AELGVLSVASVVQAAFGHVLLSYLGSSGVVFAETLSDRVLDADVDRTIGPFISVVPMP"
     CDS_motif       complement(8269..8355)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0003"
                     /evalue="3.90E-03"
                     /label="C5_DCL_263-294"
                     /locus_tag="FOXG_22940"
                     /protein_end="280"
                     /protein_start="251"
                     /score="9.7"
                     /tool="antismash"
                     /translation="VVFAETLSDRVLDADVDRTIGPFISVVPM"
     CDS_motif       complement(8689..8751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0002"
                     /evalue="3.40E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="FOXG_22940"
                     /protein_end="140"
                     /protein_start="119"
                     /score="13.3"
                     /tool="antismash"
                     /translation="IHHVLYDGTSLGYIMNDVCCA"
     CDS_motif       complement(8995..9087)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FOXG_22940_0001"
                     /evalue="2.90E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="FOXG_22940"
                     /protein_end="38"
                     /protein_start="7"
                     /score="22.8"
                     /tool="antismash"
                     /translation="FSLHSDVDIDKLEQAWATVCRGNEALRTCFI"
ORIGIN
        1 ctgagacgct cccataagac atcccacctc ctgcaagtta aggttgtttt cgccaagttt
       61 taaccatccc aaacatgata aaactcttgg cttttggccg aacggtgggg tcccctactg
      121 taaacaaacg agtctgatta actgcattat taggtctggg agttttgcag gggcgggtca
      181 gcaaccccgc ctaacctcac aacacataca ttttaagtcc aagctcagca atcgcatctc
      241 gacgcaatta tgcagacgct gcacgctgtc atgcttttat gacgacacga ttagtggctc
      301 gtgttcgaca cttcagctgc acatttcatt cttgactatc gaaagtcttc ttccatgatc
      361 agaatggcga tggttttgat gcaaaaaccg aacaagaagt tgatatgaag actgggggta
      421 actattacgc cgagtctcct ttactttctg cattacttaa ctattcatta ctgggattta
      481 ttcaagccgt cttttacagt cattatgact tgaaatgaca acagactacc acactcggca
      541 ggctcttctt gaggatttct atagcattgt ggatccagga agaggcttgt gtaatggtcg
      601 caactaacca ctacgccaca aggcaaaaga ctgggctata actgctattg tagcaattaa
      661 tggctggcac agactgacgc gacgcgaaat tacgcccgtt ttgcaatgcg tgtaaaaagt
      721 caaatttaag aacgggcctt gttttagatc ctaagcccta agtgctattg ttaagtttaa
      781 accttatact gttcgcaggc ggaaagagaa gaggaagcaa gtcgactagt tggaatatcg
      841 cacggccagg taagcagctt gcgcggccct ttaagacctg ggccggtttt acccatgcca
      901 tctaggtatc gccagataaa ggcgtcaatg tctcaacttt atatcttgaa acctgtcacg
      961 ttgtatttat ttctaagagc cccatgcggg aatgatgtcc tggagtagaa gtgtcttgat
     1021 taccgcccca aaccaccacg catacaagcc gggacgccac gtaccctgtc aagggttatc
     1081 ttgattggca ctggctaacc aatcccctat tccagtccct gcacaagtgc tgtaatctcc
     1141 tttcctatac gctctaccaa atttcgggct tcctccttat ccattagtcg tccttgcacg
     1201 cgaacaccaa acccaattgt gtctgttagg ctatcaggtg caacatcaat gtaaacattc
     1261 tctttaggca agtaggatat atcgagctta gatatcgacg tgcccgagct atccttatcg
     1321 taaaagggct ctgatggtat aaagtcggta ggcacaccta tcgggagatg ctccaacaag
     1381 cccttcagtt gctttgattc tggattggtt tccgcagctt gggatatggg ttgcatccaa
     1441 agtaggttca accacacatt aaacaaatgc aaagatgtat actcagtgcc ttccctccaa
     1501 gattttagaa tatcacgtaa tgaactttgc cctcgtacgg tactcgttct gctagtgtag
     1561 cctggatcaa tcgggccttt tcaccaactt gaagagactc agcctccccc ttagggaaga
     1621 catttttaat ggtgagagga gtgacgttca gacaagggcc cgtcatatga tcgatattgt
     1681 taaaagcagc tgatcggcca gtctagtata gacccagtgt tgggcttggc agaccagtat
     1741 ctcgagcaag aatacgaaag actgcgagga tgacaatgct ttgaaaagag acatttgagg
     1801 atcggcagac tctgtccaaa tgagcaaaat ccttgacggc ctcccaagca ccaacaaaca
     1861 actgactgtt cttttgagac atctcatatt taaccttgac gctgtcagaa ggtttaatga
     1921 gggtgggaac gctgtggcca attgccaagc gccaatagcc tcatccaggt cctccaatga
     1981 ctgtaatgtg aactcaataa atgaggcaaa atcgggcctg gatgtcggct ttactctgcg
     2041 gtaatgactg gtaagttcat tgataaaaag aggcatcgtc catgcatcat atatggcatg
     2101 atttatgaga acatggattc catctctgtc ggcgcccttg agaaggagaa gacgtacagg
     2161 cggtgtcttc aaggatgacg gcttcaacgc agcctctcgt gcctgagtta tggcgagatt
     2221 ctctagactt tccgtagagg ttatgacctg aaatgtcccg tcgttgcggc cacattcgct
     2281 caagacgatc tgaacgactt cagaaggcga gatagcatag aagcaagtcc tcaaaatggg
     2341 attattgtcg cgcaataaga accaagcgtc tttcatagtt tccaagttga tgcgctctga
     2401 gcattaaaat ggccaggcgg gctcgaagag tgtccgccct gtctggagcc atgaagcaag
     2461 atgatacatt tgaccactga ggcagggaag gattttctca atcgcatttt gcttcattcc
     2521 caactgtaca atcacatcct tcttgacact gctatagtcc ttgataagtg actgcttact
     2581 ggtattctcc tgtggcatat cgtgtatgcg tagacaagtg ccacggagag tgtttccctg
     2641 aaggatgtca gaaacaccag ctttaaaacc ggccgcgcgg cacatagacg caacccgaat
     2701 cgcagaaagt gagtccaagc caatgctgaa gatgcttgta tctggttgaa tagcctcaat
     2761 ggacactttg gaaactttcg acaatatgtc tcggatgaca ggctcatgag acggccctgg
     2821 tgtgctgatc accgagacag cactatcaga aggcgatcca aagctgaggg gtaagctctg
     2881 aagctcgtct ggaaatattg tcacacatcg taagggatgc tgaataatat cgcagaatgc
     2941 ttgactgaag tccttgagag tccggtcgag atccctttta gccatgaatt ctccttggca
     3001 cgaggcgcga actgtgattg ctttgtctgt ttgttcaacc tcggtattca tcctgtactc
     3061 ggatttagga atgtagtcat ccgtgacata aggcatccaa atcttgctat ccatcgggtc
     3121 atcttgcaat gcccgcacac tcttctggac cacaaacaat gtgtcgacta atgtagccgc
     3181 acttagaaca cccttgcatc tcagagactt ctgtacctcg tgcaaaggag catgctcatg
     3241 agtctgtgcc tcagtagtga acttttgtat catctgaact tttttgcgat tactgatgaa
     3301 tttgggatca agcgtcaccc tcttcgccac tatgttgaac agaggtccaa ctacgtgctc
     3361 agcctcgagt cccaacgacg agcacccagc gaggacctga ccaaatgcta cgtctcgttt
     3421 ctctgtcaac gtggcgagaa ccttggcata ggcaagattt gtaacactct gcaccgtcac
     3481 ttccatctct ttgcatctct cgagtatttc cgtcatatca aggtcaacct tggcttcaga
     3541 atagaacatc tctgagcata attgttgatg agaggataat ggcagcggtt tggcttcata
     3601 gccttcgaaa gtgctggtcc agaattgaca agcctcagtc tggtcttgtg atagggaacg
     3661 gactgcggtc gcaaatggtg gtcgcattgg tagcgagatg ccttggtaga ctgaagctag
     3721 gtcgttgaag ataaagggca gcgaggcacc accataaagt gcgtgatgca tgataataac
     3781 cagaaggttt tcttcatcct cactgataat cacaggttga attggtggtg ttgaaaaggc
     3841 cgattgtgta tccaatctca ccagttgcat gaccgcctga gcgatgttgg tacccggtgg
     3901 aacagatatt tcctgccaac taggtggaga gtcgctgtga acgtgccaac ccagtaatag
     3961 tccatctcca actcgggaac aggatggaat gatgtgcgca ggatatcctt ggccattgcc
     4021 ataagtcgat aagcttcttt caatcgatca acaacagtcg actccgtgag tcttacgatg
     4081 tgaagatgaa cataaacaat ccctttggat tcaatggttt gagtgatcat agcagtctgt
     4141 agtggactgc atttgaagac tgactcaact gtgtcgtctg aactgagccg ttccacttga
     4201 catgtaaatt catcgagcag gatatcgtca tcataattgg accggggtgg gctcggaacc
     4261 tcagctgcgg ttttctcaaa aacactgtga gccaatgctc caatgctaga gaaacgcatc
     4321 acttcagccg gcgaggcaga gacccccgca tcacgaagct ggctggagaa ttgtatggcg
     4381 gttacggaat ccagtccaag actcaagaat gatgtgttcc tcgatatctg ctgcccttcc
     4441 agaccactga aacgcttgac aagatcgcaa atctcaacct ctaggttcga ccacggacga
     4501 ccctcccagt ctttcttggt ttccattatg gcggtagcac ttggccaaga aagattgaga
     4561 gaattaagag aaatatatgg attcgatacc agggcggata gaatcaggtt cagcttttcc
     4621 ataatatctt gggcatcgtc tgtctggcca aaagatgatg tgaaaccaca tgtcaggaga
     4681 acgcgcttgt tcttctcatc cgcctccacc tctagggcaa gaggatactc tgaaggcatg
     4741 ctgctttcca tcccttccca taacccatga ctctgacccg gggcagattt ggtgaacgag
     4801 aagaggcagt caaagatggg gccctctgcc ttgatccacc gctggatatg tcgcagagag
     4861 ttatgttgat aatctagggc ctcagaatta cccttgtgca catgttttac aacatcttcc
     4921 acggaagaca ggttttccat gttgagtcgg gcagggatag tggcaatgca tggtagaaga
     4981 acagagtttg ctcctgcgac tggtaacacc cttccagaaa gtacaacacc gtaggtcaca
     5041 tcagatgcgc ttactgaatc ggccaaggtc agagcaaaga ccgcctgagc cagtgaagat
     5101 agtgtggatt tcaagcgggc tgcgcagctc tcgagctcag ggagagatgg ccacaacatc
     5161 gtggagtgga catgccgagt agggtctgat acgggtttct tgaaagtcgt tggtctgcaa
     5221 ccagcaagtg tcaggcgcca gtacgactcg gacctttcga tattctggga atagacatgc
     5281 ttgatgaaag cctcaggtga tcctcgcttg ggcggcgcca tatctggtag atatcgcgcg
     5341 gcaaagtctt gaagcaacat attaaatgat acgccgtcat acagaccgtg atgtatcgag
     5401 ataaataacg ccagtggttg ccttgaaacc gttgtaacca cgtgctcgat gcgaagaggt
     5461 ggaatagaca tcatgttgtt cgtaatatcc cgaccaatta cgttctggcg actctggaag
     5521 tgtgccatgg ccacctccag gtcatcgtat tgcccctcag tccagtcgcc gctgtagtta
     5581 ggcttaagta cgacctgtac aattcctgac tgcaatggaa caaaagccgt tctcaatatt
     5641 tcagtttcct tgatagtatc ctgccatgcg ttttgaagac ggactggatc agcagaaggg
     5701 ttcatcttca acacgatatg gttgacgtag agacctgaat tgctattgat ggatcgagcc
     5761 acaagaccct cttgaagggg caaacaaggt ctcacggatg ccacgggtaa ctcattcatg
     5821 ttgggtgttt gactttccaa gagctgggat tccagattcg agagtctact ctgcacttct
     5881 gaagatgaaa ctactactga cggtgggttt gtggtccatg gaaggcgagc gagttgttcc
     5941 acaacagggt tgctcataac atgtgccacg gaagcggaca agccgatatg tcgaaggcgg
     6001 acagagagat cgattgcact taagctgtcg atgccaatct cgaagatgtt ggtttgtggg
     6061 tagatcacgg actggtcgat tgcaagtgtt tggcagatgg catcagcgac agcctcttca
     6121 tttgctgtca attctctgtc cttgttcaga ccatcgtgcg ccgcctcgtt tccacggaaa
     6181 acgtcagaca aggggagact tgcaaacagc tcttgcagca gcttgctgtt taccttgtcc
     6241 gacatggcag cgaagggtat gcggtttaca ggaagtacaa tttccggcac catgtaactg
     6301 ggcaacttct ggcgacaggt gtcttggaga cccttgcata gtgtgccgat gtcagctggg
     6361 atgatggaga ggggattctt tgcgttaaat ctctgagatc ccaggcgcgc gatgaaggag
     6421 acaagctgct ggcgcgcaag gccagggtgt ttcgcaataa gagtgacaac gtcgatcgag
     6481 gccctggaag acgtcctcag aacctcggag acttcgccca actcgagccg ttggccacga
     6541 atcttggtct gatcatcacc acgcctaagg tactcaatgc tgccatctgc cattcttctt
     6601 cccacatcac cagtccggta aattttctct tggtcaggcc ctataacaaa ctctttggca
     6661 tcgggcctgt tcaaatatcc tttcccgaca agatctccgg tgaagcaaag ctcacctgtc
     6721 tgcccatgga gagcatagtc gggggtatct ggaagaagaa catgacaagc acatgaggtc
     6781 aaaggaagtc caatgttgcg cagggtgatg tgtttatgga ccggtgcaaa tgaacatcca
     6841 atcgtcagct cagtaggccc gtaagcattc atgattacca cttgacttga agagccccat
     6901 gtatctaaga ctctctggga gatcttttct ccccccgaca ctcaagagtc taagacttgg
     6961 gcaatgttca gggtgaatat cggcctgatc gagcagggta ggaatgaaac tggcatgggt
     7021 gatctccaac ttgtcaagcg ttaatctcag gtcgtccatc cgcagtggcc gtgcatcagt
     7081 agatgttgcc atgccgtggc gccatgggaa gaacatctca actatatggg gatcaaaggc
     7141 tcggctggac tggcctaacc agcgtccctt gccacccagc tcgaccgtag caggcgcaat
     7201 ccggcagact aactcggaaa gagactcgat gaaagaagac agattggctc gagaaatcat
     7261 tacccccttg ggctttccgg tcgatccaga agtgtaaaga atgtatgcag tatcttcagg
     7321 attggcaaca taggtactgt tctcggacga gaaagcaaga aactcttgtt ggactgatgg
     7381 ctcatcgatg catacgattc ggcattcgct aggtgcgccc tgaaaggtgg aagcaaaagc
     7441 cgtttcagtg aacaaaatag gagcatcacc atcctcgatc agaaatgctt tgcgatcatc
     7501 tggaagtcct tcgtcaatag gaaggtaaga gttgccagat ttcatgattc cgactagtac
     7561 agggtaggag gcaaggtttt gttgagagca aagagcaacc gcccgttttt tgatcccaca
     7621 gtggttaaga taagctgcaa cgggatttgc agaagcgttt tgctcaccgt agctcatcaa
     7681 aagctgctca gctccggctg ctgtgattga caatgtctcc tccactgctg tccactcagg
     7741 atgctgtcca gcggtagtct caacccagtc tacgggactc atatttgctg actccttcac
     7801 ggcatcgctt gggctggggg ccgagattga caacaggccc ttctcgatgt aactaggaag
     7861 agatttgaga ggcacatccg ggttgtagag catcgcgcca acaagggcat cgatctggcg
     7921 ggtgaagatg gctaattgct tcaaacccat aatggtgttc aaggacgatg cttcaaggat
     7981 aaccgtacca tcgggttccc ggaacacgtt caaagccatg gggtgttcaa cagacagccc
     8041 aaagttatct atcttggtat cccagatagt tctagctgag gcagccatga gatctacttc
     8101 gttggtagca tggaatgtaa atacagcggg gtacagagac tcccctcatt ctttcttcaa
     8161 gagcttacgg atgacttgtg cgtggatatg acgatgcttc ttggccttcg ttgacaagcg
     8221 atgctgttct gctagaacct ccctcactgt gccatttgag ttgaagggca tgggcacaac
     8281 tgaaatgaaa ggtcctatgg tacgatcgac atctgcatcc aacacacgat ccgatagcgt
     8341 ctctgcaaat actacgcctg agcttcccag gtaactcaat agcacatgtc caaaggctgc
     8401 ctgcacaaca gatgcaacgg ataagacacc aagttcagcg ttcttggcct cgagttgagc
     8461 agtgggaacc gacaatggaa ctgtctccgt gataaatctg cgaatattgt cccgctcggg
     8521 gctagttctc tctccagaga ggtccggcca tgaaggtaca tcaaagtcgg cataatctga
     8581 gagttcctgt tcccagaatt cctgcgcatc gagagacgct ttcttgcttg ggagcaggag
     8641 ggagagagca ttccggagtt gaggtctgtt gggtgcatca gcgccgtatg cacagcagac
     8701 atcattcatg atgtacccaa gcgacgtgcc gtcatacaag acatgatgaa tagaaaatat
     8761 catagttctc tcctgaaaat cgtccatgat cgtgatggcc catggtggat tctggaagtg
     8821 gcttgactga tgtcggtcct ggagtgcgac aattcttcga cgcaagttct gttgatagct
     8881 cttgcttttg cattcaatat attcccagtc aacttcatgt tgctctaaaa taacctggag
     8941 gataccggaa tcattttcgc aaccatggat cggcttctga agggcggcaa ctggaataaa
     9001 acaggtccta agggcctcat ttccccgaca gacagttgcc catgcctgct ccaatttgtc
     9061 aatgtcgaca tctgagtgaa gactaaagaa gtgatggctc caatacatct ccgaagtagt
     9121 cagtgtttca ccgagaaagc tttgttgaat tgcccttgtg gggcagacga agaagctccc
     9181 tggtatcaag gccgatactt ctcgttgcca ttcccgattg aattgctcga gatcaagcaa
     9241 gttctgcctg tgaa
//
