LOCUS       NC_013928              20870 bp    DNA     linear   CON 11-FEB-2024
DEFINITION  Streptococcus mutans NN2025, complete sequence.
ACCESSION   NC_013928
VERSION     NC_013928.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus mutans NN2025
  ORGANISM  Streptococcus mutans NN2025
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Maruyama,F., Kobata,M., Kurokawa,K., Nishida,K., Sakurai,A.,
            Nakano,K., Nomura,R., Kawabata,S., Ooshima,T., Nakai,K., Hattori,M.,
            Hamada,S. and Nakagawa,I.
  TITLE     Comparative genomic analyses of Streptococcus mutans provide
            insights into chromosomal shuffling and species-specific content
  JOURNAL   BMC Genomics 10, 358 (2009)
   PUBMED   19656368
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2013587)
  AUTHORS   Nakagawa,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2008) Contact:Ichiro Nakagawa Tokyo Medical and
            Dental University, Graduate School of Medical and Dental Science,
            Section of Bacterial Pathogenesis; 1-5-45 Yushima, Bunkyo-ku, Tokyo
            113-8510, Japan
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 00:52:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,974
            CDSs (total)                      :: 1,890
            Genes (coding)                    :: 1,830
            CDSs (with protein)               :: 1,830
            Genes (RNA)                       :: 84
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 34 of 60
            Pseudo Genes (incomplete)         :: 21 of 60
            Pseudo Genes (internal stop)      :: 25 of 60
            Pseudo Genes (multiple problems)  :: 16 of 60
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:57:33
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1466250
            Orig. end                         :: 1487120
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP010655.1.
            The complete genome sequence of S. mutans NN2025 was performed by
            Dr. M. Hattori and Dr. A. Yamashita, Department of Computational
            Biology, Graduate School of Frontier Sciences, The University of
            Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan This work
            was done in collaboration with Ichiro Nakagawa, Fumito Maruyama
            (Tokyo Univiersity), Mitsuhiro Kobata (Osaka University), Ken
            Kurokawa (Nara Institute of Science and Technology), Keishin
            Nishida , Atsuo Sakurai (Tokyo University), Kazuhiko Nakano, Ryota
            Nomura, Shigetada Kawabata, Takashi Ooshima (Osaka University),
            Kenta Nakai (Tokyo University), Shigeyuki Hamada (Nihon
            University), and supported by KAKENHI (Grant-in-Aid for Scientific
            Research) on Priority Areas Applied Genomics from the Ministry of
            Education, Culture, Sports, Science and Technology of Japan. This
            clone was isolated from a Japanese patient with dental caries in
            Osaka University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20870
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10870](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10870)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            56..991
                     /locus_tag="SMUNN2025_RS07100"
                     /old_locus_tag="SmuNN2025_1383"
     CDS             56..991
                     /EC_number="1.3.98.1"
                     /GO_function="GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803938.1"
                     /locus_tag="SMUNN2025_RS07100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1383"
                     /product="dihydroorotate oxidase"
                     /protein_id="WP_002263253.1"
                     /transl_table=11
                     /translation="MVSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSEAGSFVTK
                     TGTLEERAGNPQPRYADTKLGSINSMGLPNLGINYYLDYVTELQKQPDSKNHFLSLVGM
                     SPEETHTILKMVEASKYQGLVELNLSCPNVPGKPQIAYDFETTDQILSEVFTYFTKPLG
                     IKLPPYFDIVHFDQAAAIFNKYPLTFVNCINSIGNGLVIEDETVVIKPKNGFGGIGGDY
                     VKPTALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGTALHQEGPQIF
                     KRITKELKAIMTEKGYETLEDFRGKLNAMA"
     gene            complement(1054..1209)
                     /locus_tag="SMUNN2025_RS10560"
                     /old_locus_tag="SmuNN2025_1384"
     CDS             complement(1054..1209)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321497.1"
                     /locus_tag="SMUNN2025_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1384"
                     /product="hypothetical protein"
                     /protein_id="WP_002263254.1"
                     /transl_table=11
                     /translation="MKFIIIVLIVFSIVKIISIIWVSKIMKPKPMTPKEIEEYDRKEDQ
                     KDGFDF"
     misc_feature    1192..1207
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.49"
                     /tool="antismash"
     misc_feature    complement(1195..1210)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.33"
                     /tool="antismash"
     gene            complement(1272..1748)
                     /locus_tag="SMUNN2025_RS07110"
                     /old_locus_tag="SmuNN2025_1385"
     CDS             complement(1272..1748)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834882.1"
                     /locus_tag="SMUNN2025_RS07110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1385"
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_002263255.1"
                     /transl_table=11
                     /translation="MGLHSHNNDPNKDVYDHVLTHLKEKHIRITKTREAVISYMINSRR
                     HPSAEQIHKDLLPQYPSMSLATVYNNLKVLIDEGFVVELKLSNDNTAYFDFMGHQHLHV
                     VCESCGKITDFVDTDISHIKQEAYKQTNYVITRAQLLIYGICPDCQSKKTKKAD"
     gene            2011..2652
                     /locus_tag="SMUNN2025_RS07115"
                     /old_locus_tag="SmuNN2025_1386"
     CDS             2011..2652
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283232.1"
                     /locus_tag="SMUNN2025_RS07115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1386"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_002263256.1"
                     /transl_table=11
                     /translation="MARRKKEPARIHRKNISDAANTLFISKGITDTTMDNIAKLAGYSK
                     ATLYVYFENKEEIFFSLVYKHAKWLYETIEKIIQIQPSTQEEWQKNYLKICFALQKLCE
                     TYPIYFDGMIGHINVDMTSKETPQVYRDIYQLGLDINQLINTLIEDGVHLNYLQTELDF
                     NQSTLFFWSALSGIIRMAENKKEYYRLLGLDNKTFLEEEFLTLLACYKKG"
     gene            2659..3777
                     /locus_tag="SMUNN2025_RS07120"
                     /old_locus_tag="SmuNN2025_1387"
     CDS             2659..3777
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803937.1"
                     /locus_tag="SMUNN2025_RS07120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1387"
                     /product="hypothetical protein"
                     /protein_id="WP_002264652.1"
                     /transl_table=11
                     /translation="MKKKVIITTIAAFLFILFSVGAIIFTIGKTANTQTNIQLERTSSD
                     IEHALYYASFAANSHNTQSWKVNLDPKQKRLGVFLNNKRSLNVVDPNNRELYISIGCYI
                     QSLKKSFEAYGYNVSISNIAPSKENKYQVVLINYQKLKNNKINNKQLDIIQKRHTDKRK
                     FQKKPINRTVVSSLIKKYDNVYYYAKGSKTFKYLQKGSLAAAAKQYKSQDFLKEQGKWL
                     RFSNQEAKKKQDGISGDMLGLNPIIKTFYYLTSNHKNATSNNFVKQSKNTLINQVENCA
                     GFFVITGEQNISKWIAVGEKSQAFWYDCVRNNIAVQPISAMIEIPSYNQKFQQNLGKSQ
                     PVQLILRVGYVNSYGKNVGPRRNLKDYITVKK"
     misc_feature    3815..3824
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.51"
                     /tool="antismash"
     misc_feature    3945..3954
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            <3968..4105
                     /locus_tag="SMUNN2025_RS10165"
                     /pseudo=""
     CDS             <3968..4105
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_254231480.1"
                     /locus_tag="SMUNN2025_RS10165"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YEKSFKSLDKLEKAITNYIFDYNKKRIKTKLKGLSPVQYRTESLQ
                     "
     gene            complement(4198..4473)
                     /locus_tag="SMUNN2025_RS07125"
                     /old_locus_tag="SmuNN2025_1388"
     CDS             complement(4198..4473)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="SMUNN2025_RS07125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1388"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_002262099.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQL
                     IGFGNFEVRERAARKGRNPQTGEEIKIKASKVPAFKAGKALKDAVK"
     gene            complement(4570..5169)
                     /locus_tag="SMUNN2025_RS07130"
                     /old_locus_tag="SmuNN2025_1389"
     CDS             complement(4570..5169)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002266412.1"
                     /locus_tag="SMUNN2025_RS07130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1389"
                     /product="YpmS family protein"
                     /protein_id="WP_002278066.1"
                     /transl_table=11
                     /translation="MKQRRTGNKKNWWKWAFLLLLALNIAFWGVIISRVLSGYHSNTIT
                     SQTVKNPVKVGTITTTKEQLNQTLASYLNDYQYKGMTYSVQLTSTNIEFQGTYKLLGYN
                     VPLYIYFEPYQLKSGSVQLKVTSFSVGNLPLPASEVLSYIKSSYKLPNFVDVIPEKSVV
                     NINLQKIDNDAGIYLKSTAINLVSDEINFDILKKKR"
     gene            complement(5144..6001)
                     /locus_tag="SMUNN2025_RS07135"
                     /old_locus_tag="SmuNN2025_1390"
     CDS             complement(5144..6001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312511.1"
                     /locus_tag="SMUNN2025_RS07135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1390"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_002283295.1"
                     /transl_table=11
                     /translation="MSKRIPKGPAFFLANLLIFSLLFYFFIPTAKLSFKNSDQKSSLNK
                     SKATSFHYIAIGDSLTQGVGDTTDQGGFIPLLSQELKSNYHYNVLSSNYGVSGNTSQQI
                     LIRMRKERKIQKSLNKANLMTLTVGGNDVMTVVRKGLTNLKVSSFRQPAKTYQKHLRKI
                     IQMARRRNKNLPIYIIGIYNPYYLNFPNMTQMQDIIDNWNKGTQKVVAEYRNVYFVPIN
                     DLLYKGVNGEQKAVGTSDSEAESGEVTNDALSEGDRFHPNNVGYQIMSKAIMEKISETK
                     KNWK"
     gene            complement(5994..6833)
                     /locus_tag="SMUNN2025_RS07140"
                     /old_locus_tag="SmuNN2025_1391"
     CDS             complement(5994..6833)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="SMUNN2025_RS07140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1391"
                     /product="DegV family protein"
                     /protein_id="WP_002283296.1"
                     /transl_table=11
                     /translation="MSKIKIVTDSSITIEPDLVEALDITVVPLTVMVDGIVYSDNDLKE
                     DGKFLSLMRNSKSLPKTSQPPVGLFAETYEKLIKEGAEQIVAIHITHSLSGTLEASRQG
                     ANIAGADVTVLDSAFTDQAMKFQVIAAAKLAQKGSSLEEILARVEEVKKKTELFIGVST
                     LENLVKGGRIGRVTGLISSLLNIRVVMELKNHDLNPIAKGRGNKTFNKWLDNLIATIKD
                     RKIAEIGISYAGASDFANGLKDKLQAYVEKDIAVLETGSIIQTHTGEGAFAVMVHYE"
     misc_feature    6875..6891
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.4"
                     /tool="antismash"
     gene            complement(7055..8713)
                     /gene="recN"
                     /locus_tag="SMUNN2025_RS07145"
                     /old_locus_tag="SmuNN2025_1392"
     CDS             complement(7055..8713)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312509.1"
                     /locus_tag="SMUNN2025_RS07145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1392"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_002283297.1"
                     /transl_table=11
                     /translation="MLLEIAIKNFAIIEEISLNFERGMTVLTGETGAGKSIVIDAMNMM
                     LGSRASIDVIRHGSPKAEIEGFFSVDKNPSLEQLLADQGIAFSDELIIRREILQNGRSI
                     SRINGQMVNLATLRAVGQYLVDIHGQHDQEELMRPQKHIQLLDEFGDEVFQVSKQHYQD
                     LFDRYRDLRKRVLNKRKNEQEHQARIEMLEYQIGEIEAANLQSGEDTKLLKQRDKLMNH
                     KLIVDTLTNAYVLLDNEDFSSLTNVRSAMNDLQSLEEYDAEYKELSNNLSESYYILEDV
                     SKRLETILDHMDFDANTLVKLEARLDVINTITRKYGGSVDDVLAYFDNISKEYNHLTGN
                     DLAFDDMERELKVLERSLLEAAAQLSQKRHAIAETLSQEIKQELKDLYMDKADFKVVFT
                     KGKFNREGNETVAFHISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRREDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGNHGQVLAISHIPQVIAISDYQYFIEKQSSKATTVSTV
                     RLLNQEERIEEIAKMLAGDNVTQAARQQAKELLKK"
     misc_feature    8726..8740
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(8730..9194)
                     /locus_tag="SMUNN2025_RS07150"
                     /old_locus_tag="SmuNN2025_1393"
     CDS             complement(8730..9194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002278192.1"
                     /locus_tag="SMUNN2025_RS07150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1393"
                     /product="ArgR family transcriptional regulator"
                     /protein_id="WP_002266416.1"
                     /transl_table=11
                     /translation="MKKRERLELIKKIVLENEIETQKELVKLLKNEGLQATQATISRDI
                     NEVGIIKVPASNGRYIYGLSKEISKKEESTPKPAEKAVKFISDQVAGLEHLIHIDVVPG
                     NSYLLKRFLLERFEGLIFSLLADDDSLLLIVKNAKDSDRIRQEIKSWMAN"
     gene            complement(9181..10008)
                     /locus_tag="SMUNN2025_RS07155"
                     /old_locus_tag="SmuNN2025_1394"
     CDS             complement(9181..10008)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834880.1"
                     /locus_tag="SMUNN2025_RS07155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1394"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_002287749.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFNTREQAKRGVMAGLVVNVINGERYDKPGE
                     KIDEATELKLKGDKLKYVSRGGLKLEKALKVFAISVDGQITLDIGASTGGFTDVMLQNG
                     AQLVYAVDVGTNQLVWKLRQDERVCSMEQYNFRYAEPSDFEQGQPTFASIDVSFISLNL
                     ILPALAKILTDSGQVVALIKPQFEAGREQIGKHGIVKDKSVHETVLETVTTFATNYGFT
                     VKELDFSPIQGGHGNIEFLAYLEKSAQAQNQVLTKIKSIVEQAHKEFKKNEET"
     gene            complement(10001..10870)
                     /locus_tag="SMUNN2025_RS07160"
                     /old_locus_tag="SmuNN2025_1395"
     CDS             complement(10001..10870)
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002279431.1"
                     /locus_tag="SMUNN2025_RS07160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1395"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_002266418.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.6e-51, bitscore:
                     170.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKIKYINQAIKHYYAQTHVSQDLVEAVLYSVAAGGKRIRPLLL
                     LEILQGFGLVLTEAHYQVAASLEMIHTGSLVHDDLPAMDNDDYRRGQLTNHKKFGETTA
                     ILAGDSLFLDPFGLLAKADLRADIKIKLVAELSDAAGSYGMVGGQMLDIKGEHVQLNLD
                     QLAQIHANKTGKLLTFPFVAAGIIAELSEKALARLRQVGELVGLAFQVRDDILDVTASF
                     SELGKTPQKDIEADKSTYPSLLGLDKSYAILEDSLNQAQAIFQKLALEEQFNATGIETI
                     IERLRLHA"
     gene            complement(10867..11088)
                     /locus_tag="SMUNN2025_RS07165"
                     /old_locus_tag="SmuNN2025_1396"
     CDS             complement(10867..11088)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262107.1"
                     /locus_tag="SMUNN2025_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1396"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_002262107.1"
                     /transl_table=11
                     /translation="MSNKKKTFEENLQDLEEIVNQLETGEIPLEEAITQFQKGMALSKD
                     LQKTLESAEKTLVKVMQADGSEAEMDEL"
     gene            complement(11063..12406)
                     /gene="xseA"
                     /locus_tag="SMUNN2025_RS07170"
                     /old_locus_tag="SmuNN2025_1397"
     CDS             complement(11063..12406)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678150.1"
                     /locus_tag="SMUNN2025_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1397"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_002266419.1"
                     /transl_table=11
                     /translation="MSDYLSVSSLTKYLKLKFDRDPYLERVYLTGQVSNFRRRPNHQYF
                     SLKDEKAVIQATMWSGIYRKLGFELEEGMKINVIGRVQLYEPSGSYSIIIEKAEPDGIG
                     ALAVQFEQLKKKLAEAGYFDDRHKQRLSQFVKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     DILLFPTKVQGEGAAQEVADNIRLANERTDLDLLIVGRGGGSIEDLWAFNEEIVVQAIF
                     ESHLPIISSVGHETDTTLADFAADRRAATPTAAAELATPVTKADLLAFLKERQMRSYQA
                     VMRLIRQKDEQVKKLQRSVIFRQPERLYDAYVQKLDHLRTHLLTKVRQVYDVYDSKEHL
                     LRQRLLSLNLSGCIQRYQAQLKQDQRLLLSHMSSQYDSKLARFEKAQDALLSLDTTRIV
                     ARGYAIVQKDNHIIQSTQQIKKGDRLHLEMKDGQVQVEVENVKQEENI"
     misc_feature    complement(12736..12751)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.6"
                     /tool="antismash"
     gene            12850..14592
                     /gene="lytS"
                     /locus_tag="SMUNN2025_RS07175"
                     /old_locus_tag="SmuNN2025_1398"
     CDS             12850..14592
                     /codon_start=1
                     /gene="lytS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262109.1"
                     /locus_tag="SMUNN2025_RS07175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1398"
                     /product="two-component system sensor histidine kinase
                     LytS"
                     /protein_id="WP_002267218.1"
                     /transl_table=11
                     /translation="MLMILLFQRLGIIMILAFLLVNNSYFRQLIEERSKREKLVLIIIF
                     GIFVIISNMTGIEITSDKSLVERPILTTISHSDSLANTRTLVITTASLVGGPLVGTVVG
                     FIGGVHRFFQGNFSGAFYIVSSALVGYISGRLGDQLKTNNLYPSTSQVIVISIIAESIQ
                     MLFVGFFTGWDLVKLIFIPMMLLNSLGSTLFLAILKTYLSNERQLRAVQTRDVLDLTQQ
                     TLPYLRQGLSQQSATKVCNIIKQHTNFDAVGLTDRTNVLAHIGVGQDHHIAGQAVKTDL
                     SKSVILNGQPQIALDKTAIACPDQSCLLNSAIVVPLKINNETVGALKMYFSGDKKMTEV
                     EENLALGLAQIFSGQLAIGIAEEQNKLANIAEIKALQSQINPHFFFNAINTISALIRLD
                     ANKARYALMQLSTFFRTSLQGGQDREITLEQEKAHVDAYMNLEKLRFPDKYQLNYHITV
                     STKMTLPPFGLQVLVENAVRHAFKERKKDNHICISITDQGEFYKVAVSDNGQGISPNMI
                     DKLGQETVSESKGTGTALVNLNNRLNLLYGSASQLHFDSTDQGTTVWYEIPYQKGDKDE
                     HFNS"
     gene            14573..15307
                     /gene="lytR"
                     /locus_tag="SMUNN2025_RS07180"
                     /old_locus_tag="SmuNN2025_1399"
     CDS             14573..15307
                     /codon_start=1
                     /gene="lytR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262110.1"
                     /locus_tag="SMUNN2025_RS07180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1399"
                     /product="two-component system response regulator LytR"
                     /protein_id="WP_002266421.1"
                     /transl_table=11
                     /translation="MNILILDDEMLARQELTFLIQQSKELDHPDIFEAEDISSAEKILF
                     RQQIDLIFLDISLSEENGFTLANQLEQLAHPPLVVFATAYDHYAVKAFESNAADYILKP
                     FEQGRVDKALAKVKKIQHLSTIDETATTEKKGMELLTLTLADRSIVLKMPDIVAASIED
                     GELTVSTKSTSYTIKKTLNWFKTRAKTNYFLQIHRNTVVNLEMIQEIQPWFNHTLLLVM
                     VNGEKFPVGRSYMKELNAHLTL"
     misc_feature    15371..15383
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    15419..15430
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.05"
                     /tool="antismash"
     gene            15483..15950
                     /gene="lrgA"
                     /locus_tag="SMUNN2025_RS07185"
                     /old_locus_tag="SmuNN2025_1400"
     CDS             15483..15950
                     /codon_start=1
                     /gene="lrgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262111.1"
                     /locus_tag="SMUNN2025_RS07185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1400"
                     /product="holin-like protein LrgA"
                     /protein_id="WP_002264708.1"
                     /transl_table=11
                     /translation="MKHTSKVTQSKSAPMFIQMSIYAAILLVSQLISELLPKALPIPTT
                     VIGLILMYVLLCSHIIKIEWVDSLGSLLISMIGFMFVPSGISLAANLNILKAEGLQLVA
                     VISLSTILMLVIVTYITSIILSIKKVNVASLWEKWTAHSFEKKFSKKVEGK"
     gene            15952..16683
                     /gene="lrgB"
                     /locus_tag="SMUNN2025_RS07190"
                     /old_locus_tag="SmuNN2025_1401"
     CDS             15952..16683
                     /codon_start=1
                     /gene="lrgB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271503.1"
                     /locus_tag="SMUNN2025_RS07190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1401"
                     /product="antiholin-like protein LrgB"
                     /protein_id="WP_002278065.1"
                     /transl_table=11
                     /translation="MALLKSPIFGICFSLILYTIGQDLFKKSKGFFLLQPLFFAMVAGI
                     IVLVLLAKGLGTDVKTLYTQAYKPGGDLIFWFLNPATIAFAVPLYKKNDAVKKYWKEII
                     SSLIIGMVVSLVIIVAISKAIGLSQASTASMLPQAATTAIALPIAHAIGGNTAITAMAC
                     ILNAVIIYALGKKLVAFFHLNKSEIGVGLGLGTSGHTVGAAFALELGELQGAMAAIAVV
                     VIGLVVDLVIPIFSYIIGLVH"
     gene            complement(17008..17841)
                     /locus_tag="SMUNN2025_RS07195"
                     /old_locus_tag="SmuNN2025_1402"
     CDS             complement(17008..17841)
                     /GO_function="GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322331.1"
                     /locus_tag="SMUNN2025_RS07195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1402"
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="WP_002278064.1"
                     /transl_table=11
                     /translation="MIIDDLLTKKIIKPRPLNSHKGTFGRVLLIGGNYPYGGAIIMAAL
                     ACVNSGAGLVTVATHKDNITALHSHLPEAMAFDMVEKDRLSEQITAADVVLMGPGLAED
                     DLAQTTFDVVWQAIKPKQTLIIDGSAINLLAKRKPAIWPTKQIILTPHQKEWERLSGLT
                     IPEQIEAATQTALAHFPKETILVAKSHQTKIYQGQKIGHIQVGGPYQATGGMGDTLAGM
                     IAGFVAQFHTDRFEVAAAAVFLHSYIADQLSKEAYVVLPTRISAEITRVMKEMSE"
     gene            complement(17838..18692)
                     /locus_tag="SMUNN2025_RS07200"
                     /old_locus_tag="SmuNN2025_1403"
     CDS             complement(17838..18692)
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263561.1"
                     /locus_tag="SMUNN2025_RS07200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1403"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_002278063.1"
                     /transl_table=11
                     /translation="MTEIIDGKALAQKLQLHLANKVEQMKEKHGLVPGLVVILVGDNPA
                     SQVYVRNKERSATKAGFKSETIRLSDSISEEELIEIIEGYNQDPSFHGILVQLPLPAHI
                     NDKKIILAIDPHKDVDGFHPMNTGHLWSGRSMMVPCTPAGIMEMLSAYHVDLEGKHAVI
                     IGRSNIVGKPMAQLLLEKNATVTLTHSRTKHLSEVTRCADVLIVAIGQGNFVTEEFVKE
                     GAVVIDVGMNRDKNGKLIGDVNFDHVAQKASLITPVPGGVGPMTITMLLEQTYQAALRS
                     VTK"
     gene            complement(18813..18959)
                     /locus_tag="SMUNN2025_RS07205"
                     /old_locus_tag="SmuNN2025_1404"
     CDS             complement(18813..18959)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299875.1"
                     /locus_tag="SMUNN2025_RS07205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SmuNN2025_1404"
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_002264704.1"
                     /transl_table=11
                     /translation="MSTFIIAILIAAGAFLGIRHYIKQKGSCGDCDCACPVKDEMKKSS
                     KTH"
ORIGIN
        1 gcggttgacc ttatctagtg ttacaataga aaaaattcat tattttggag gttccatggt
       61 ttcaactcat acaacaattg gctcttttga ctttgataat tgtctcatga atgctgcagg
      121 ggtttattgc atgacacgtg aagaattagc agctattgat cattcggaag caggttcttt
      181 tgttaccaag actggtacgc tagaagaacg tgcaggaaac cctcaacccc gctatgctga
      241 cacaaaatta ggctctatta attcaatggg cctgcctaat ctaggtatta actattattt
      301 agactatgtc acagaattgc aaaaacagcc cgatagcaaa aatcactttt tatccctagt
      361 tggcatgtcg ccagaagaaa cccataccat tcttaagatg gttgaagcca gcaaatatca
      421 aggtttggtg gaactcaatc tttcctgtcc aaatgttccc ggtaaaccac aaatcgccta
      481 tgattttgaa acaacggacc aaatcctttc agaagttttc acttacttca ctaaaccact
      541 aggtatcaag ttaccacctt attttgacat tgtacacttt gatcaagcag ctgctatttt
      601 caataaatac cctctgacat ttgttaattg tattaattct attggaaacg gcttagttat
      661 tgaagatgaa acggtcgtca ttaaaccaaa aaatggcttt ggaggcattg gtggcgatta
      721 cgtcaaacca acagcgctag ccaatgttca tgctttttac aagcgcctca acccttccat
      781 ccaaattatc ggaaccggcg gtgtcaaaac aggtcgcgat gctttcgaac atattctctg
      841 tggcgccagc atggttcaaa tcgggacagc tcttcatcaa gaaggtcctc aaattttcaa
      901 acgtattact aaagagttaa aagccatcat gacggaaaaa ggttatgaaa ccttggaaga
      961 ctttcgtggt aagctgaatg ctatggctta aagaaatctt tttatttctg tataccaaaa
     1021 gacctgactg agaatctcct cagtcaggtc tttttaaaaa tcaaaaccat ctttttgatc
     1081 ttccttgcga tcatactcct caatttcttt tggagtcatc ggctttggct tcattatttt
     1141 acttacccaa ataatactaa tgattttaac aatagaaaac actattaaaa caatgataat
     1201 aaatttcatt taatgactca cctcctattt cccatatgat aagttttctc tctagataat
     1261 caataagcaa attaatcggc ttttttagtt ttcttgcttt gacagtctgg acaaatacca
     1321 taaatcaaaa gctgtgctct cgtaatcaca taatttgtct gcttatatgc ttcttgcttg
     1381 atatgagaaa tatcagtgtc tacaaaatca gtaatcttac cacaagactc acaaacaaca
     1441 tgcaaatgct gatgccccat aaaatcaaaa taagctgtat tatcattgct tagctttaat
     1501 tcaacaacaa agccttcatc aatcaggact ttcaaattat tatagaccgt tgctaaactc
     1561 atacttggat actgaggaag aagatcctta tgaatttgtt ctgcactcgg atgacggcgg
     1621 gagttaatca tataagaaat aacagcttct cgtgttttag taatacgaat atgcttttct
     1681 tttaaatgcg ttaatacatg atcataaaca tccttattcg gatcattatt atgagaatgc
     1741 agtcccattt ttgactcctt cgttattctt tttttctatt atacactatt tttaaagata
     1801 cagaaaaatt agtgcctagc atcatcaagt agcctttact tttcctaaat gataaaaaat
     1861 atgcaaaaaa ctgtctatca attttatctc taaaaatcat tcaaacaatc tctaggataa
     1921 ttaatacaaa gatgtttaaa attgacaaaa gaaagaaata tactataatt aattaaaccg
     1981 ctagtttaat taattatagg aggatctctt atggcgagac gaaaaaagga acctgctcgt
     2041 attcatcgta aaaatatttc agatgctgct aacacactct ttatcagtaa aggtattact
     2101 gatacaacaa tggataatat tgctaaatta gctggatata gtaaagcaac tttatatgtt
     2161 tattttgaaa ataaagaaga aatctttttc tcattagttt ataaacatgc caaatggctt
     2221 tacgagacta ttgaaaaaat tattcagatt caaccaagca ctcaagaaga gtggcagaaa
     2281 aattatttaa aaatttgttt tgcattgcaa aaactatgtg aaacctatcc aatatatttt
     2341 gacggaatga ttggtcatat caatgttgat atgacctcta aagaaacacc tcaagtatat
     2401 agagatattt accaattagg gttagatata aatcagttaa ttaacacact tattgaagat
     2461 ggtgttcact taaactatct tcagacagaa ttagatttta accaatcaac tctttttttc
     2521 tggagtgcac tatcgggtat cattcgtatg gcagaaaaca aaaaagaata ttatcgctta
     2581 cttggtcttg ataacaaaac ctttttagaa gaagaatttc taactttatt agcatgttac
     2641 aagaaaggat aaaggaacat gaagaaaaaa gttattatta caacaatagc agccttttta
     2701 tttattcttt ttagtgtagg agccattatt tttactattg gaaaaaccgc taatacccaa
     2761 actaatattc aattagaaag aacttcttca gacatcgaac acgcgttata ctatgcttct
     2821 ttcgcagcta attcccataa tactcagagt tggaaagtta atttagatcc taagcaaaag
     2881 agattagggg tttttctgaa taataagcgt tccttaaatg tcgttgaccc aaataatcga
     2941 gaactttata tttcaattgg ttgttatatt caatctctaa aaaaatcatt cgaagcttat
     3001 ggatataatg ttagcatttc taatattgct ccttctaaag aaaacaaata tcaagttgta
     3061 ttgataaatt atcaaaaact aaaaaataat aaaattaaca ataaacaatt ggatatcatc
     3121 caaaaacgtc atactgataa aagaaaattc cagaaaaaac caattaatag aacagtcgtt
     3181 tcaagtttaa ttaaaaaata tgataatgtt tactactatg ctaagggaag taaaacattt
     3241 aaatatctac aaaaagggag tctcgcggct gctgctaaac agtataaaag tcaagatttt
     3301 ttaaaagaac agggaaaatg gttgcgtttt tctaatcagg aagctaagaa aaaacaagat
     3361 ggtatctctg gtgatatgtt agggttaaat cctataatta aaacctttta ttatctaaca
     3421 agtaatcata agaatgccac gagtaataat tttgtcaaac agagtaagaa cactttaatt
     3481 aatcaagtag agaactgcgc aggttttttt gtaattacag gtgaacagaa tatttctaaa
     3541 tggattgctg ttggtgaaaa atcgcaagct ttctggtatg attgtgttag aaataacatt
     3601 gcagttcaac cgattagtgc catgattgaa attccctcct ataatcaaaa gtttcagcaa
     3661 aatttaggta aatcacaacc tgttcaatta attttacgag taggttatgt taacagttat
     3721 ggtaaaaatg ttggtcctcg tcgaaattta aaagattata ttactgtgaa aaaataatct
     3781 gctattatta taacttagct atatgacaca gctagaacgg gaagtagcaa acaagtatta
     3841 tggtagcact cactgtaaaa gaaaacatgc taatagaaca ttaaaaagac catagcaaac
     3901 tgacctgcac cctaaaagtt gggcagaaaa tctaacaatt ggggtgtttt ttgatgaaat
     3961 taacgtatat gaaaagtctt tcaaatcgct cgacaaactt gaaaaagcca tcactaacta
     4021 catttttgac tacaacaaga aacgaatcaa gacaaaacta aaaggactca gccctgtgca
     4081 atacaggact gaatcccttc aataatttct tgtccaactt tttggggtca gtacagaaac
     4141 gtttgtacac tctaaaatct aaagattaaa ttttagaaaa gtacatttgc caaaatctta
     4201 ttttacagcg tctttaagag ctttaccagc tttgaatgct ggaactttag aagctttgat
     4261 tttgatttct tcacctgttt gagggttgcg acctttgcgt gctgcacgtt cgcgaacttc
     4321 aaagttacca aaaccaataa gttgtacttt ttcacccttt gcaaggtaag atgatactgc
     4381 tgagaagaca gcgtctactg ctgcagctga atctttctta gtcaattcag tagcttctgc
     4441 tacttttgca atcaaatctt gtttgttagc catttaacaa atcctccaat atttttataa
     4501 gcctttatag gctttaacag gttctatctt acctaaaaaa cttagatagg tcaagtattt
     4561 aatgccattt taacgttttt tctttaaaat atcaaagttt atttcatcac taaccaaatt
     4621 tatagctgtt gactttaaat aaatgcctgc atcattgtct attttttgca aattgatatt
     4681 aacaacagac ttctctggaa taacatcaac aaaatttggc agtttgtaac ttgatttaat
     4741 ataactaaga acctctgatg ctggcagagg aagattgcct actgaaaagg aagtcacttt
     4801 aagctggaca gatccgcttt ttaactgata aggttcaaaa tagatataaa gaggtacgtt
     4861 ataacctaga agtttataag ttccttgaaa ttcaatgttt gttgaagtta gttgaacact
     4921 gtaggtcata cccttatact gataatcatt caaataactt gccaaggtct gattcaattg
     4981 ttctttagtt gtcgtaattg ttccaacctt aacaggattt tttactgttt gacttgttat
     5041 tgtattagaa tggtaaccgc tcaaaacacg actgataatc actccccaaa aagcaatatt
     5101 gagtgctaat aaaagcagaa aagcccattt ccaccaattt tttttatttc cagttcttct
     5161 ttgtttcact gattttctcc attattgctt ttgacatgat ttgataacca acattattag
     5221 gatggaaacg atctccttca gaaagggcat cattggttac ttctcctgac tctgcctcac
     5281 tgtcagatgt tccaacagcc ttttgctctc cattaacacc tttataaagt aaatcgttta
     5341 tgggaacaaa ataaacgttt ctatactctg cgacaacctt ttgcgttccc ttattccaat
     5401 tgtcaataat atcctgcatt tgcgtcatat tagggaaatt taaataataa ggattgtaaa
     5461 taccaatgat ataaatgggg agattcttat tccttcttct agccatctgg ataatttttc
     5521 gcaaatgctt ctgataagtt ttagctggct gcctaaaaga agatactttt aagtttgtta
     5581 atccctttcg aacaacagtc ataacatcat ttccaccaac tgttaaggtc attaaattag
     5641 ccttattcaa acttttttga atttttctct cttttcgcat ccgtatcaaa atttgctggc
     5701 ttgtattgcc cgaaacacca taattactgc ttaaaacatt atagtgataa tttgatttca
     5761 actcttgcga taaaagggga ataaagccgc cttgatcagt cgtatcaccg actccttgtg
     5821 tcaaagagtc accgatagca atatagtgaa aagatgtcgc tttggatttg tttaatgaag
     5881 atttctgatc gctattttta aaagataact tcgctgttgg aataaaaaaa taaaataata
     5941 agctaaaaat aagaagattt gcaagaaaga aagcaggtcc tttaggaatt cttttactca
     6001 taatgcacca ttactgcaaa agcaccttca cctgtatgag tctgaataat tgaccccgtt
     6061 tctaaaacag caatatcttt ctcaacataa gcttgtaact tgtctttaag accattagca
     6121 aaatctgaag ccccagcata ggaaatgccg atctcagcaa ttttgcggtc tttgatagtc
     6181 gcaatcaaat tatccagcca cttgttaaac gttttattac cgcgtccttt cgcaatagga
     6241 ttaagatcat ggtttttcag ttccataaca actctgatat tgagaagaga actgattaag
     6301 cctgtcacac ggccaattcg tccaccttta accagatttt ctaaggttga gacaccaata
     6361 aaaagttcgg ttttcttttt tacttcttca acccttgcca aaatttcttc tagactgcta
     6421 cccttttgag ctagtttagc agccgcaata acttgaaatt tcatggcttg atctgtaaag
     6481 gcagagtcta atacagtgac atctgctcca gcaatattag ctccttgacg tgaggcctca
     6541 agtgttccag ataaggaatg ggtaatatga atagcaacaa tttgttccgc cccctcttta
     6601 ataagctttt cataagtttc tgcgaacaga ccaacaggtg gttggcttgt tttagggagt
     6661 gacttactgt ttcgcattaa agaaagaaat ttcccatctt ccttaagatc gttatcagaa
     6721 taaacaatgc cgtcaaccat aacggttaaa ggaacaacag tgatatccaa tgcttcaact
     6781 aaatcgggct cgattgtaat agaagaatca gttacaattt taattttact catttcttat
     6841 cctgcttcat ttcttttcta aatttatatt agtattgtta ttatatcaaa taatcaagat
     6901 ttagggaaaa ttttaaaaga cagaaaggat taaaattact ttgctgttaa actttaagat
     6961 agtttaaaat agttctctac aagcaatagt ccaaatcaaa acaaaaagat tgaagtaaga
     7021 gcatatttat taaaatactt tctataccaa tctcttattt ttttaatagt tctttagctt
     7081 gctggcgcgc agcttgggtc acattatccc ctgccaacat cttagcgatt tcttcaattc
     7141 tttcctcttg atttaaaagg cgaaccgttg agacagttgt ggctttgctg ctttgttttt
     7201 caataaagta ctgataatca ctgatggcaa tgacttgcgg gatatgggaa atagctaaaa
     7261 cttgaccgtg attgcctatt ttgtaaattt tttgagcaat agcctgcgcg acacgtcctg
     7321 aaacacctgt atcaacttca tcaaaaacaa tgctagtctt atcttcacga cgtgaaaaag
     7381 ctgacttaat ggctaacatg agacgagaca gctctccacc agaagcgact ttgaccaaag
     7441 gcttaaagtc ttcgccagga ttagtcgaaa tatgaaaagc gactgtttca tttccctcgc
     7501 gattaaattt tcctttagta aaaacaactt taaaatcagc cttatccatg tagagatctt
     7561 ttagttcctg cttaatctcc tgagacaagg tttccgcaat ggcatggcgt ttttgactca
     7621 attgagctgc tgcttctaat agtgagcgct ccaaaacttt tagttctctt tccatatcat
     7681 caaaagcaag gtcatttccc gtcaaatgat tatattcctt actgatattg tcaaaataag
     7741 ccaaaacatc atcaactgaa ccaccatact tacgcgtgat ggtgttgata acatcaagac
     7801 gtgcttcaag tttaaccaaa gtattggcat caaaatccat atgatccagt atggtctcta
     7861 gacgtttgct aacatcttct aaaatatagt aagattcact gagattattg gacaattcct
     7921 tgtactcagc atcatattct tccaaactct gcaaatcatt catagctgaa cgaacattgg
     7981 tcaaactcga aaaatcttca ttatcaagta aaacataagc attggttaag gtatcaacaa
     8041 taagcttatg attcataagt ttatcacgtt gttttaagag cttggtatcc tcaccagatt
     8101 gtaagtttgc tgcttcaatc tctcctatct gatactccag catttcaata cgtgcttgat
     8161 gttcttgctc attcttacgt ttattcaaga cgcgcttacg taagtcccga tagcgatcaa
     8221 ataagtcctg ataatgctgc ttgcttacct gaaatacctc atcaccaaat tcatccaaca
     8281 actgaatatg cttttgcggc cgcatcagtt cttcttgatc atgctgtcca tgaatatcaa
     8341 ctaaatactg cccaacggca cgcagagttg ccagattaac catttgacca ttgatacgac
     8401 taatactgcg cccattttgt aaaatctcac ggcgaatgat tagctcatct gaaaaagcaa
     8461 ttccctgatc agccagtaac tgctctaaag aaggattttt atccacagag aaaaaaccct
     8521 caatctctgc tttaggacta ccatgacgaa tgacatctat gctggctcta ctgcctagca
     8581 tcatattcat ggcatcaatg acaatagact tccctgcacc tgtttcaccg gtcagaacag
     8641 tcattcccct ttcaaaattg agtgagattt cttcaataat agcaaaattt ttaatggcaa
     8701 tttctaaaag catactcact ccttatgatt taattggcca tccaagattt gatttcttga
     8761 cgaattctat cactgtcttt agcattttta acaatcaaaa gcaaactgtc atcatctgcc
     8821 agcaagctaa aaataagtcc ttcaaatctc tctagtaaaa aacgtttcaa taaatagcta
     8881 tttccaggaa caacatcaat atgaatgaga tgctctaaac ctgccacctg atctgaaata
     8941 aacttaactg ctttttcagc tggttttggt gttgactctt cttttttgct tatttcctta
     9001 gaaaggccat aaatatagcg accatttgaa gctggtactt taatgatacc gacctcatta
     9061 atatcacggg aaattgtcgc ttgcgttgct tgtaagcctt cgttctttaa aagtttgacc
     9121 aattcttttt gtgtttcaat ttcattttct aaaacaattt ttttaattaa ttctaatcgt
     9181 tcacgtttct tcattctttt taaattcctt atgtgcttgt tcaacaatcg atttaatctt
     9241 agtcaagact tgattttggg cttgagctga tttttctaaa taggctaaaa attcaatatt
     9301 gccatgaccg ccctgaatgg gagaaaaatc aagttcttta actgtgaatc cgtaatttgt
     9361 cgcaaaagtt gttactgtct ccaaaacagt ttcgtggact gacttgtcct taacaatacc
     9421 atgtttacca atctgttcac gacctgcctc aaattgcggt ttaattaaag caacaacttg
     9481 accactatct gttaaaatct tagctaaggc tggtaatatt aaattgagtg aaataaaact
     9541 cacatcaatg gaagcaaaag ttggctgtcc ttgttcaaaa tcgctaggct ctgcatagcg
     9601 gaaattgtat tgctccatgc tgcagacgcg ttcgtcttga cgtaatttcc acaccaactg
     9661 attggttcca acatcaacag catagactaa ttgagcacca ttttgcagca tgacgtctgt
     9721 aaaaccaccc gttgaagcgc caatgtccaa agttatctgt ccatctactg aaatggcaaa
     9781 aacttttaat gctttttcca atttcaaacc gccgcgactg acatatttta atttgtctcc
     9841 ctttaacttt aactcagtcg cttcatcaat tttctcgccg ggtttatcat aacgttctcc
     9901 attgatgaca ttgacaacca aacctgccat aacacctcgc ttggcttgtt ctcttgtgtt
     9961 aaacagtcct tgtttatagg ctagaacatc cactctttcc ttaggcatgg agacgcaacc
    10021 tttctattat tgtttcaatt ccagtagcat taaattgttc ctctaaagct aatttttgga
    10081 aaatagcttg cgcttgattg agagaatctt ccaaaatggc ataggacttg tccaagccca
    10141 aaagactggg ataggttgat ttatcagctt cgatatcctt ttgtggggtc ttaccaagtt
    10201 ctgaaaaact agctgtcaca tctaaaatat catcacgtac ttgaaaagcc aaaccaacta
    10261 attcacccac ctgacggagc cgagcaaggg ctttttctga taattctgct attattcctg
    10321 cggctacaaa aggaaaagtc aagagttttc ctgtcttatt ggcatgaatt tgagctagtt
    10381 ggtctaaatt gagttgaaca tgttcaccct taatatccaa catttgccca ccgaccatac
    10441 catagcttcc tgcagcatct gacaattctg ctactaattt tatcttgata tcagccctta
    10501 agtccgcctt ggctagcaaa ccaaaagggt ctagaaaaag actgtcacct gccaagatgg
    10561 ctgtcgtttc accaaatttc ttatgattgg tcagctgtcc ccgcctataa tcatcattat
    10621 ccatagcagg caggtcatca tgaacgaggc tgccggtatg aatcatctct agacttgctg
    10681 ccacctgata gtgagcttct gtaagtacca aaccaaagcc ttgcaagatt tccaatagta
    10741 agagaggacg aatccgttta ccgcctgcag caacagaata caagaccgct tcaaccaaat
    10801 cctgagacac atgagtttgc gcataataat gcttaatagc ctgattaatg tatttaatct
    10861 tatctttcac aactcgtcca tttctgcttc actgccatca gcctgcatga ctttgaccaa
    10921 ggtcttttca gcagactcca aggttttctg caaatcttta gaaagcgcca ttcctttttg
    10981 gaattgagta atagcttctt caagaggaat ttcaccggtt tctaactggt tcacaatttc
    11041 ttctaaatcc tgtaaatttt cttcaaatgt tttcttcttg tttgacattt tctacctcca
    11101 cttggacctg cccatctttc atttcaagat gcaagcgatc tccttttttg atctgttggg
    11161 ttgattgaat aatgtgatta tctttttgaa caatagcata gccacgcgcc acaatccgag
    11221 tcgtatccag tgacaaaagc gcatcttgtg ctttttcaaa acgggctaat ttactatcat
    11281 attgactgct catgtggctt aacaataaac gctgatcttg ttttaattgt gcttgatagc
    11341 gctgaataca ccctgataaa ttaagggaca acaatctttg tctcagcaaa tgttccttgc
    11401 tatcataaac atcataaacc tgccgcacct tggtcaacaa atgtgttctt aaatgatcca
    11461 atttttgaac ataagcatca tagagtcttt caggctgtct gaaaataact gatctttgca
    11521 gtttcttaac ttgttcatcc ttttgtctaa tcagacgcat aacagcctga taagatctca
    11581 tctgtctttc tttaagaaaa gctaataaat cagccttggt cacaggtgtt gccaattcag
    11641 ctgctgctgt tggcgttgct gctctgcgat ctgccgcaaa atcagccaag gttgtatccg
    11701 tctcatgtcc aacgctggaa ataatgggca gatgcgattc aaaaatggcc tgcactacaa
    11761 tctcctcatt aaaagcccag agatcttcaa tagaaccccc accacgacca acaatgagca
    11821 ggtctaaatc agtacgttca ttagccaaac gaatgttgtc agccacttcc tgtgctgctc
    11881 cttcaccttg aactttggtt ggaaaaagta aaatatctac accgggaaaa cgacgcgaga
    11941 ctgttgtgat aatatctcta ataaccgctc cactaggact ggtgacaaca ccaatctttt
    12001 taacaaactg cgacagtctt tgtttatgcc tatcgtcaaa ataaccagcc tcagccagtt
    12061 ttttcttaag ttgttcaaac tgaacagcca gtgcaccgat accatctggc tctgcctttt
    12121 caatgatgat ggaataagaa ccactaggtt catacagttg cacacgacca ataacattga
    12181 ttttcatgcc ttcttcgagc tcaaagccca atttcctata aataccgctc cacatggttg
    12241 cctgaatgac agctttctca tctttaaggg aaaaatactg atgattggga cgtcttctga
    12301 aattagaaac ctgacctgtc agataaactc gttccaaata aggatcgcga tcaaatttta
    12361 attttaaata tttggttaaa gaggatactg ataaataatc tgacataaat ctcatctaaa
    12421 gaccaaagac aaaggaaaaa ggtattcttg gaatcctgtt ccaaagtcta aaacaaatga
    12481 ccgtttttct tgatctttcg cctgtcttta tcttggctcc ttttccgtta atatagctgt
    12541 tattattata ccaaaaaatg aaaatttata cttccttttg aaatagaaaa atgagagcag
    12601 cagttcattt atctcctcat aagaatggag aatgacagaa aaatataaat tgatgatata
    12661 tacaacctaa ccttttcatg gcaatctaac cagtaacttt taaaaataag caagcttgaa
    12721 aatctaaaat aaaacgttta caatagaaaa ctagaaacag acgtcatcaa aaaaatattt
    12781 cgaaaaagag ctttttttgc taataagtaa ctgtccgtat tagatttcaa taataggaga
    12841 aagcgcaata tgttaatgat attattattt cagagacttg gtattatcat gattctggca
    12901 tttttactag tcaataacag ctattttcga cagttgattg aagaacgttc taagcgtgaa
    12961 aagctggttc ttattatcat ttttggtatt ttcgtcatca tttccaatat gacaggaatt
    13021 gaaatcacta gcgataaaag tttggtggaa cgtcctattt taacgactat ttctcattca
    13081 gattctctag ctaatacgag aactttggtt atcacaacgg ctagcttagt cggcggtcct
    13141 ttagttggaa ctgttgtggg tttcattggt ggtgtccatc gtttctttca agggaatttt
    13201 tctggtgctt tttacattgt cagttctgct ttggtaggat atattagtgg tcgactgggt
    13261 gatcaattaa aaactaataa cctttatcca tctacttcgc aggtcattgt tatcagcatt
    13321 attgctgaaa gtattcaaat gctctttgtc ggtttcttta ctggctggga tttggttaaa
    13381 ctgattttca ttcctatgat gttgcttaac agtctaggtt cgaccttatt tctagctatt
    13441 ctcaagacct acttatccaa tgaaagacag ctgagagctg ttcagactcg ggatgtttta
    13501 gatttgacgc agcaaaccct gccttattta agacagggac tgagtcagca atcagctact
    13561 aaagtgtgta atatcattaa gcagcatact aattttgatg ccgttggtct gactgatcga
    13621 accaatgtcc tagctcatat cggcgttggt caagatcatc atattgccgg acaagcggtc
    13681 aaaacagatc tctcaaaaag tgttatttta aacggtcagc cacaaattgc cttagataaa
    13741 acagccattg cctgtccaga ccaaagctgt ctcctcaatt cagccatcgt cgttccgctc
    13801 aagatcaata atgagacagt tggggcttta aaaatgtact tttctggtga taagaagatg
    13861 accgaagtcg aagaaaatct tgccctaggt ctcgcacaaa ttttttctgg acaattggcc
    13921 atcggtattg ccgaggaaca aaataagctg gctaatattg cagaaatcaa ggccttgcag
    13981 tcccagatta atcctcattt cttcttcaat gccataaaca ccatcagtgc tttgattcgt
    14041 cttgatgcca acaaagctcg atatgctctc atgcaattaa gtactttttt ccgaaccagt
    14101 ttacaaggcg gacaagatag agaaatcact ttagaacagg aaaaagcgca cgttgatgct
    14161 tatatgaatc ttgaaaagct gcgctttcct gataaatatc aactgaatta tcatattact
    14221 gtttcaacta aaatgaccct gcctcctttt ggtttgcagg ttttggttga aaatgcagtg
    14281 cgtcatgctt ttaaagaacg caagaaagac aatcatattt gtatttccat aacagatcag
    14341 ggagagtttt acaaggtggc cgttagcgat aatggtcagg gtatttctcc taatatgatt
    14401 gacaaattag gacaggaaac tgtatctgaa agcaagggaa caggaacagc ccttgttaat
    14461 ttaaacaatc gcctaaattt actttatggc agtgctagtc agttacactt tgacagtaca
    14521 gatcaaggaa caaccgtctg gtatgagatt ccttatcaaa aaggagataa agatgaacat
    14581 tttaattctt gatgatgaaa tgttggcaag acaagagtta acttttttaa ttcagcagag
    14641 taaggaactt gatcatcctg atatttttga agctgaagat attagcagtg ctgaaaaaat
    14701 tctctttcgc cagcagattg atttaatttt tcttgatatt tcactcagcg aggaaaatgg
    14761 ttttaccttg gccaaccaat tagagcaatt ggcacatcct ccacttgtcg tctttgcgac
    14821 agcctatgat cattatgccg ttaaagcttt tgaaagcaat gctgctgact atattttgaa
    14881 gccttttgag caggggcgtg tggataaagc tttggctaaa gttaagaaaa tacaacactt
    14941 atctacaata gatgaaacag ctacgacaga aaagaaaggt atggaactgt taacactgac
    15001 tttagcagat agaagcattg tccttaagat gccagatatt gtggccgcta gcattgaaga
    15061 tggggaacta actgtcagta ccaaaagcac gagctacacc atcaagaaaa cattgaattg
    15121 gtttaaaact cgcgccaaga ccaattattt tctgcagatt caccgcaata cggttgttaa
    15181 tctggaaatg attcaggaaa ttcagccttg gtttaaccat acgctcttac tggtgatggt
    15241 caatggtgaa aaattcccag tcgggcgttc ctatatgaaa gagttgaatg ctcatttgac
    15301 cttataaatg aattagtttc attaactcct caaaattttc atttgacgat tttacattgg
    15361 cattaagaag ttggatattg caattcagct tctttttttt gcaatcgggg acaattttga
    15421 aaacgtttta cacaaaatga gctacaataa cattgtcaag aaaggaagga gtcgttcgta
    15481 ttatgaaaca cactagtaaa gtaacacaat caaaatcagc acctatgttt attcaaatgt
    15541 ctatctatgc tgctattctg ctcgtttctc agcttatttc agaattattg cctaaagcct
    15601 taccgattcc aaccaccgtt attggtttaa ttctcatgta tgtcctcttg tgcagccata
    15661 ttatcaaaat tgaatgggtt gattccttgg gttccttatt aattagtatg attggcttta
    15721 tgtttgtccc atcaggtatt tccctagcag ccaatttaaa tattctcaaa gctgaaggat
    15781 tgcagttggt cgctgttatt agcctatcga ccattctcat gctagtcatt gtcacctata
    15841 tcacttctat cattctgtcc attaaaaagg tgaatgtggc aagtctgtgg gaaaaatgga
    15901 ctgctcatag ctttgaaaag aaatttagca agaaagtaga gggaaaataa gatggcactg
    15961 ttaaaatcac ctatttttgg tatttgtttt tcattaatcc tttatacgat cgggcaagat
    16021 ttattcaaaa agagtaaagg cttctttctc ttacaacccc ttttctttgc tatggttgca
    16081 ggcattatcg tacttgtttt attggcaaaa ggattgggaa ctgatgttaa aaccttatat
    16141 actcaagctt ataaacccgg cggagatttg attttctggt tccttaatcc cgcaaccatt
    16201 gcctttgccg ttccacttta taagaaaaat gacgctgtca aaaaatattg gaaggaaatc
    16261 atcagcagtt tgattatcgg tatggtcgtt tccttagtca tcattgttgc tatttcaaaa
    16321 gctattggtt taagccaagc tagcactgct tctatgctgc cgcaggcagc aacaacagcc
    16381 attgccctcc ctattgctca cgctatcggc ggcaatactg ccatcactgc catggcttgt
    16441 atcctaaacg ccgttatcat ctatgcttta ggcaaaaaat tagttgcttt cttccacctc
    16501 aataagagtg aaatcggtgt tggcttaggt ttaggaacat ctggtcatac agttggtgca
    16561 gcctttgctc tagaattagg agaactacaa ggtgccatgg ctgccatcgc agttgttgtc
    16621 atcggcctcg tcgttgactt ggttattcct atctttagct acataatagg attagtgcac
    16681 taaaaattaa aactgctatc gataagacaa aagcctctca cggatgattc cgcgaaaggc
    16741 tttttaaaag taggggtatg aaaggaaaac aaaaaaattc atttaattaa taaaattcta
    16801 cctcacataa ttgtcaatta agcttataaa tcgtattcag caaagacctc tttagcatct
    16861 atcatattac catctaaaat atcttgatat cctttgtcta atttagcttt taagcttgat
    16921 agattacttc ttgttctgaa gatttaatag gtgaggaaag gcaattcatc aaatttaaaa
    16981 atatcgttta atactatttt cgtcatatca ctcactcatc tccttcatca ctcttgttat
    17041 ctccgcactg attctggttg gtaggacgac gtaggcctct ttgctcaatt ggtctgctat
    17101 gtaggagtgg aggaagacag cggctgcggc aacctcaaag cggtctgtgt gaaattgagc
    17161 aacaaagcct gcaatcattc cagccaaggt atctcccata ccgccagtcg cttgataggg
    17221 accgccaact tggatatgtc cgattttttg tccttgataa atcttggtct gatgggattt
    17281 tgcgactagg atggtttctt ttggaaaatg agctagtgct gtttgtgttg ctgcttctat
    17341 ctgttctgga atagtcagtc cagacaatct ttcccattct ttttgatggg gtgttaggat
    17401 tatttgcttg gttggccaaa tagctggttt tcttttagct aatagattta tagcagagcc
    17461 atcaataatc aaagtctgtt ttggtttgat agcctgccaa accacatcaa aggttgtttg
    17521 agccaagtca tcttctgcca agcccggtcc cataagaacc acatctgctg ctgttatttg
    17581 ctctgacaaa cgatcttttt caaccatatc aaaagccata gcttcgggta aatggctgtg
    17641 cagagctgtg atattgtcct tatgggtcgc aaccgtcacc aaaccagctc cgctattgac
    17701 acaagcaagg gcagccatga tgatagcacc accgtaaggg tagttgccgc caatcaaaag
    17761 gacacggcca aaagtcccct tatgactgtt aagaggacgt ggtttaatta tttttttcgt
    17821 taaaagatca tcaataatca tttggtcaca cttcttaaag ctgcttgata ggtttgttcc
    17881 aaaagcatgg tgatggtcat aggaccgaca ccacccggaa caggagtaat gaggctggct
    17941 ttttgagcga cgtggtcaaa gttaacatcg ccgataagtt ttccattttt gtcacggttc
    18001 atgccaacat caatgacaac agcaccttct ttgacaaatt cctcagtgac aaaatttcct
    18061 tgaccaatag caacaataag cacatccgca cagcgtgtga cttctgataa atgtttcgtt
    18121 ctagaatggg tcagggtaac tgttgcattt ttttcgagca ataactgcgc cattggcttc
    18181 ccaacgatat tggaacgacc aataataact gcatgcttcc cttcaagatc aacgtgatag
    18241 gcactcagca tttccataat accagcgggg gtacaaggta ccatcatgga acgaccgctc
    18301 cacaaatgac cagtattcat aggatgaaag ccatctacat ccttatgagg atcaatggct
    18361 aaaatgattt tcttatcatt aatgtgagcc ggcagcggca attgaaccag aataccatgg
    18421 aaggaaggat cttgattata accttcaata atctcaatta attcttcttc actaatagag
    18481 tcagataggc gtatggtttc acttttaaat cccgccttgg tagctgagcg ctctttatta
    18541 cgcacataga cttgactggc aggattatca cctactaaaa tcaccacaag accgggaaca
    18601 agcccatgtt tttctttcat ctgttcaact ttattggcta aatgcaactg cagcttttgt
    18661 gccaaggctt taccatcaat aatttctgtc attctcatct cctgaaaaaa tactgctttt
    18721 attataccaa aaaaggcgag cagataacac gctgctacac ctttttttct atatttaaat
    18781 attataatca gttcaaaata tgaagctttg tcttaatgtg tcttgcttga ttttttcatc
    18841 tcatctttaa cagggcaggc acagtcacaa tcgccacaag aacctttctg cttaatataa
    18901 tgacgaattc ctaagaaagc tccagctgca attaagatag caataataaa ggttgacata
    18961 gtcattcttc ctttctatta gttatgactt aaacttaaat tatctaaggt aatcactttt
    19021 tctttgacct gacgtggttt tctaataata aagtaaagca tcacaagcaa taaaacaaga
    19081 gctaaacctg tccaaagcgt cactggcttg ccataaaaag caactaaacc aagctggtaa
    19141 ataattaagc taacaagata agccagaccc gtttgataag caatagccac taaagtccac
    19201 ttcagatttc ccatttcgcg tttgatagct ccgattgagg caaaacaagg cgcacaaagc
    19261 aaattgaagg tcaaaaatga ataggctgcc aaagctgtat aatccccctg aaggctaacc
    19321 catagtgaat gcgttgtttc tgttgcatcg ggattattgt agagaattcc aaaagttgca
    19381 actactgttt ccttagctgc aagaccagtc agagcagcta cagtcgcctt ccaatttcca
    19441 aaaccaagcg gtgtaaagat ccaagccaag agacgaccaa gactagccag aatactgttt
    19501 tccgtatcaa ctgaatgcaa agtaaaatta taggaactca taaaccagat taaaacggtt
    19561 aaactaaaga taatcgttcc agcacgttta acaaaactca tagccttacc aaaagcatag
    19621 cgcaaaacag catcaacctt tggtagatga taacttggta attccatgat aaaaggactc
    19681 gtataaccgc ctaaaaaact agttttctta agggcaatac ctgataaaat aatagcaatc
    19741 attcccatga aataagcact tggagctatc caaggattat gagggaaaaa ggctcccgca
    19801 attaaggcaa tgacggacag cttagctgaa caaggcataa aagtcgttgt cataatggta
    19861 atacggcgat cacgttcatt ctcaatggtt cgactggcca taattcccgg aacaccacac
    19921 cccgttgaaa taagcatagg aataaaggat tttcctgaaa gtccgaaacg tctgaaaatc
    19981 cgatccataa caaaagcaat tcgactcata taaccaatat cttctagaat tcccagacag
    20041 ataaagagga caaaaatttg cggtaaaaag ccaagaactg ttccaacacc agcaacaacc
    20101 ccatcaataa tcaacgattg tagccaagcc tgcactttca atgcttctaa aacacctgta
    20161 acaaattcag gtacgtattt accaaaaaga acatcattaa cccaatccgt ccccattgtt
    20221 cccactgttt gaatggacaa gtaataaact aagaacataa cgaccgcaaa aatgggcaga
    20281 gccaaaacgc gattagtcac aattttatca attttatcag aagcagacat cttaaaatca
    20341 ttatcttgac tttgtgccat ttggctcaca cgttcaatga aagcataacg ctgattaatc
    20401 acgatggact ctgaatcttc tgtgaagact tcctcggtga tttgaatgat gtctttaatt
    20461 tccttctttt gaaagggaga taaatctaat tcctcttcaa ccaaacggtc gcgctcaaat
    20521 aatttgatgg cataaaaacg gctagaacgt tctggtactg tctgaccgag aacctcaata
    20581 atttgggcaa tcgccgcttc aaatttggca tcgtaagttg ggtattgaac actatcaaca
    20641 ctgcccttag ttgtttgact ggctttttta acagccttgt caacgcctgt atttttcaaa
    20701 gcactggtcg caacaactgg cactcccatc tgataagcca atttatcact attaatagat
    20761 tttccttgat tttttaacac atcgctcata ttaagcgcaa tcgttacagg aattcctgtc
    20821 tcaattaact gcgtcgttag gtaaaggttg cgttccagat tcgtggcatc
//
