LOCUS       NC_009480              23162 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Clavibacter michiganensis subsp. michiganensis NCPPB 382, complete
            sequence.
ACCESSION   NC_009480
VERSION     NC_009480.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Clavibacter michiganensis subsp. michiganensis NCPPB 382
  ORGANISM  Clavibacter michiganensis subsp. michiganensis NCPPB 382
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Microbacteriaceae; Clavibacter.
REFERENCE   1
  AUTHORS   Gartemann,K.H., Abt,B., Bekel,T., Burger,A., Engemann,J., Flugel,M.,
            Gaigalat,L., Goesmann,A., Grafen,I., Kalinowski,J., Kaup,O.,
            Kirchner,O., Krause,L., Linke,B., McHardy,A., Meyer,F., Pohle,S.,
            Ruckert,C., Schneiker,S., Zellermann,E.M., Puhler,A., Eichenlaub,R.,
            Kaiser,O. and Bartels,D.
  TITLE     The genome sequence of the tomato-pathogenic actinomycete
            Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a
            large island involved in pathogenicity
  JOURNAL   J Bacteriol 190 (6), 2138-2149 (2008)
   PUBMED   18192381
REFERENCE   2  (bases 1 to 3297891)
  AUTHORS   Linke,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAY-2007) Linke B., Center For Biotechnology,
            Bielefeld University, Universitaetsstrasse 25, 33501 Bielefeld,
            GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 01:14:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,224
            CDSs (total)                      :: 3,169
            Genes (coding)                    :: 3,147
            CDSs (with protein)               :: 3,147
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 22
            CDSs (without protein)            :: 22
            Pseudo Genes (ambiguous residues) :: 0 of 22
            Pseudo Genes (frameshifted)       :: 4 of 22
            Pseudo Genes (incomplete)         :: 18 of 22
            Pseudo Genes (internal stop)      :: 4 of 22
            Pseudo Genes (multiple problems)  :: 3 of 22
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:51:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2211400
            Orig. end                         :: 2234562
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AM711867.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23162
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="8"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23162
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23162
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13162](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13162
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(765..1613)
                     /locus_tag="CMM_RS10530"
                     /old_locus_tag="CMM_1958"
     CDS             complement(765..1613)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type dipeptide/oligopeptide/nickel transport
                     systems permease components"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038645.1"
                     /locus_tag="CMM_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1958"
                     /product="ABC transporter permease"
                     /protein_id="WP_012038645.1"
                     /transl_table=11
                     /translation="MSATLATIDAPRARPRSRARLAGGLVIPVLVVLVMLLWALVPGLF
                     ASGSPTASVAPSLQAPSAAHWFGTDSTGRDLYTRVVFGASQSVVGAVVAVLVGLVVGTL
                     LGVVAGTVGGIVDDVLMRLVDVLLAIPGLLLSLSIVILLGFGTTNAAIAVGVTSIAVFA
                     RLSRAEVVRVRISEYVEAAYGSGGTLVQVLRRHVLPNSLTPVIALAALQFGSAILQIST
                     LGFLGYGAPPPTPEWGLLVAEGRDYVATAWWLTVLPGAVVVAVVLATNRISQSIRGGQL
                     A"
     gene            complement(1610..2545)
                     /locus_tag="CMM_RS10535"
                     /old_locus_tag="CMM_1959"
     CDS             complement(1610..2545)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="ABC-type dipeptide/oligopeptide/nickel transport
                     systems permease components"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010155979.1"
                     /locus_tag="CMM_RS10535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1959"
                     /product="ABC transporter permease"
                     /protein_id="WP_012038646.1"
                     /transl_table=11
                     /translation="MSYAIRRAGQAVIVLVLAYVVAYVLLAALPGDAVLARYGGPELGL
                     SPEQLAAIRESYGADRPLIVRLGESAAAFAQGQLGYSVQSGAAVSTLLATAIPSTLVLA
                     VLGLLVAVVLAVPIAFLATYGGARWIRRVFRDLPPLLVSLPVFWVGIILIQVLSFRLGL
                     VPIIGASPGEALILPVLTIAVPIAAPLAQVLIRSIDDVSAMPFVEVVRARGADTPWLLL
                     HGVGRNALLPTLTMAGLLFGELVGGAVVTEAVFGRAGVGQLTVQAVASRDSPVLLAVVV
                     LSTVAYVVINLAVDLLYPVLDARLRRGGAR"
     gene            complement(2586..4238)
                     /locus_tag="CMM_RS10540"
                     /old_locus_tag="CMM_1960"
     CDS             complement(2586..4238)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="ABC-type dipeptide transport system periplasmic
                     component"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012298662.1"
                     /locus_tag="CMM_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1960"
                     /product="TIGR04028 family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_012038647.1"
                     /transl_table=11
                     /translation="MPRPPRPVIALTALVAATGLMAGCSAGGGGDQAASGEPKAGGTLT
                     YLEPQTWTTLYPPAAGFYPNGAVVNNITDRLLWQDPETLELEPWIATALPEVNAAATEY
                     TFDIRTDVTYSDGTPLTAQNVVANFDLYGKGDVDRALTVSEAINNYDRGEVVDADTVRF
                     HFTAPAPGFAQATSTINSGLVSDSTLAKADDGFGPGQAETVIGSGPFTVSGESVGTQIQ
                     LAAREDYDWAPPEAAHQGRPLVDGVDLIVAAEDSVRVGTVVAGQADVARQIEAPDEAQF
                     RTGDLQLVAAATNGVDNGINLRFRTPQLEDVRVRQAIIAGVDRQAILDTLFSDSYPLAT
                     GVLAKSALGYVDTSSYYAHDADKAAALLDEAGWVPGSDGIRQKDGRKLELVVNEALPQP
                     RSKEVVTLIQSQLAEIGVEVELFSGDQAAQTKASQDPDALEAYHSMVGRSDYDVLKSQY
                     SSTNRNVLLNRNPADGSIADPELDALLTRIASEPTTEGRQAASAATQQRIADQAYVLPL
                     FEEPQVYGLRGDVRGFATESVGRPVFAGVWLDR"
     gene            4452..4943
                     /locus_tag="CMM_RS10545"
                     /old_locus_tag="CMM_1961"
     CDS             4452..4943
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490607.1"
                     /locus_tag="CMM_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1961"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_012038648.1"
                     /transl_table=11
                     /translation="MTTHPTVRPAVPDDADGIAEVHIRTWQETYAHLLPAVYLDGLDVA
                     ARAEQWRGSLGDASGAPTVVALDDDRIVGFALAGPARDEDPPRPFQLYAINVVASAHGT
                     GAGQALFDAAVGDSPAYLWAADDNPRAAAFYRRNGFARDGGVERQTYQGAEMVTVRMVR
                     "
     gene            complement(4980..5726)
                     /locus_tag="CMM_RS10550"
                     /old_locus_tag="CMM_1962"
     CDS             complement(4980..5726)
                     /codon_start=1
                     /function="Uncharacterized protein conserved in bacteria"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780271.1"
                     /locus_tag="CMM_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1962"
                     /product="ABC transporter permease"
                     /protein_id="WP_012038649.1"
                     /transl_table=11
                     /translation="MFRAEAVKLKRSSIWIIAVLLPLLAVVTGTINLANNTQTLDSGWA
                     SFTSQVVLFYGLLFYSMGISLLAAAIWRVEHRGTNWNALLTATARPIRLVLAKIVAILV
                     PVALMQAVLVGGTAVSGLFVLRLDGPFPVAFLLVGLIATVAALPLIAVQSLLSLLLRSF
                     AAPVALCLVGCVAGVAAVTSAALRPLAEVLPQAINTRALNLGSTAIAGSGGLTTADTLP
                     LLATSVGLGALVVLLTLAAIRVVKLR"
     gene            complement(5732..6472)
                     /locus_tag="CMM_RS10555"
                     /old_locus_tag="CMM_1963"
     CDS             complement(5732..6472)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005885337.1"
                     /locus_tag="CMM_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1963"
                     /product="ABC transporter permease"
                     /protein_id="WP_231840595.1"
                     /transl_table=11
                     /translation="MAIEFRKMHRLRSLPLLIGMVVAVAALSSASQFAGSTRAGFDDPG
                     AHPWAALLLGYTLMAAMTSPILTAVIASRQTDIEHQAGGWILAAGAGRTAGELCRAKLV
                     ALAVLLVPAVLIQSLLVIAAGYAAGIRVPVEVGPWALYTLLLYLVDVAFCALHVWLAAR
                     VENQLISVGVGMLGAFLAVFSLLLPSVASRAIPWGYYAVISQAGQSDAGVGYVASPLGW
                     IAGFLVVVAAAFALATIRLDRVER"
     gene            complement(6481..7380)
                     /locus_tag="CMM_RS10560"
                     /old_locus_tag="CMM_1964"
     CDS             complement(6481..7380)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type multidrug transport system ATPase
                     component"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015780269.1"
                     /locus_tag="CMM_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1964"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012038651.1"
                     /transl_table=11
                     /translation="MSAVIATRGLTKRFRDHVAVDALDIEVPQGSVYGFLGPNGSGKST
                     TMKMLLGLTQPTSGEIHLFGQRLTPATRGGLLPSIGSMIEAPAGYGHLTGWENMRIVRD
                     MLGLAEAQVERAFATVRLTQHRDKLVRRYSLGMKQRLGIAMALARDPSLLVLDEPTNGL
                     DPAGIEEVRSLLMDLAGQGITVMVSSHLLDEIEKMAGVLGILADGRMIFQGTRAELFEH
                     SIPDLVIETSAPDRAMAEVAGAARSPEGIRLSARSKDETADIVRRLVAADVPVHEVRRL
                     PQSLEDVFMDITGRGGQL"
     gene            complement(7534..8208)
                     /locus_tag="CMM_RS10565"
                     /old_locus_tag="CMM_1965"
     CDS             complement(7534..8208)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011775166.1"
                     /locus_tag="CMM_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1965"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012038652.1"
                     /transl_table=11
                     /translation="MTDAPAPIRVVVVDDQSLVRDGFARIVDAQPDMAAVGVCADGEQA
                     VARVVELRPDVVLMDVRMPVLDGIEATRRLVEGGRAEGTRILGLTTHDTDSYAIRMLRA
                     GAVGFLLKDSTAVQLVDAIRSVHNGTFAASMSTTQRLLERLAVERTAPPDPDTAALDVL
                     TDRERVVFTRLVTGASNPEIARDLSIAEVTVKTHVGHILTKLAVRDRVHLVIWAHRRGL
                     AA"
     gene            complement(8205..9341)
                     /locus_tag="CMM_RS17005"
                     /old_locus_tag="CMM_1966"
     CDS             complement(8205..9341)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Signal transduction histidine kinase"
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="CMM_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1966"
                     /product="histidine kinase"
                     /protein_id="WP_012038653.1"
                     /transl_table=11
                     /translation="MRRGSLRAQGDQVVAGAAVVLCAIMGVLGQPDWIWSSLMALTLAV
                     RHARPVTAALLATAISSAHMLATSSLLFPGDVVLLVAAYSVAAHAADRLRHVGLALGAC
                     FVVVLAARTLTGGELGSTGSVGMVIALVSVSFAVAWAAGLLERRRSEAVRTAELRTTLS
                     ERDADARTRLAAYEERERISDDMHDVLAHTLTSVIVQAESGRATAPSPEASRMFRTISE
                     TSRAALHEVRGLLAPTDADADVRPIPGWDDVDALVEGFRGSGLGIDRQDAGSPRPLLPG
                     VGFAVYRVVQESLTNAMRHGAGGTARLRVEWSPDALAITVANAVVRDKRGCPVQEHRGL
                     AAIRRRCALYGGQARYACDDEFVLQARWPTAPLGGSTP"
     gene            9703..9909
                     /gene="micA"
                     /locus_tag="CMM_RS10575"
                     /old_locus_tag="CMM_1967"
     CDS             9703..9909
                     /codon_start=1
                     /function="Lantibiotic precursor"
                     /gene="micA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038654.1"
                     /locus_tag="CMM_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1967"
                     /product="lantibiotic michiganin-A"
                     /protein_id="WP_012038654.1"
                     /transl_table=11
                     /translation="MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRRVVSP
                     YMSSSGWLCTLTIECGTIICACR"
     CDS_motif       9703..9843
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRRVVSPYM"
                     /locus_tag="CMM_RS10575_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9844..9909
                     /prepeptide="core"
                     /locus_tag="CMM_RS10575_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="2109.5"
                     /monoisotopic_mass="2108.0"
                     /core_sequence="SSSGWLCTLTIECGTIICACR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNDILETETPVMVSPRWDMLLDAGEDTSPSVQTQIDAEFRR
                     VVSPYM"
                     /leader_location="[9702:9843](+)"
                     /alternative_weights="2127.5"
                     /alternative_weights="2145.5"
     gene            10001..13162
                     /locus_tag="CMM_RS10580"
                     /old_locus_tag="CMM_1968"
     CDS             10001..13162
                     /codon_start=1
                     /function="Lantibiotic modifying enzyme"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CMM_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1968"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_012038655.1"
                     /sec_met_domain="DUF4135 (E-value: 6e-90, bitscore: 299.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.3e-44, bitscore:
                     148.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITAAELSLLQASRLRERRAATRADARPVPELTRAWRDDALVDD
                     GTHAAYLAGQLLDGDDLVALLAGDAWTPRAASADWLARVDPWLVHPPVSAEAYATANGH
                     LVVEDTRVAGLPFAALLGPMVGAQRAHLDGRPWLSRTATADLLDGLAERLATLSLRALL
                     AELARDPAPGRHARLDARLADPEHRAELLSRHPVLARDLVTAIGSWRAHVARILDRLHA
                     DHGDLVRMGLATERLDALEAVDLSSGDPHDGGQSVATLRFSDGSLLVYKPRDCRVFALY
                     RDLVDALAPALPGEIRLRAAAVLPRDGYGWVEFVAHAEDAASAIPLSRHLGRLGSLLAV
                     AHVLGASDLHLENVIASADGPVPIDLETLIQNRSEVDGEDGTALRRASRMLNASVLGSG
                     ILPVQLTTGEGTSIDVSVSTGGLHGAGTTATVHQVVDAATDRMRIEAREMPVGRSRNQP
                     PGATLARIRSGRAALADGYERTFRAIVERRAEVRAILSAAPDISSRHIVRATRSYSLLL
                     TEMRRPRPLRSGIDRDHLLRHLWTRVEEHPADAALVEAEERALWRLDVPLFSTRMDARA
                     LIADDEEAGPQRFARSTREDVLDRLARLTLDDLPESLRLVDESVLAATATPDGDDDARD
                     DARGRQAADATASLARAPRVDDDALREAARGQARILLASAVLGRDDATWIGVSSSLDSS
                     GLEYRPAGPTLYDGLAGIAFAATHAHGVLPGLGLDDLAGRAMHAVTAILDDWTRGLIDL
                     PVGAYSGATGLLHALAHHDARVGGDGHRDLRAAAVRRLGEVAHEDPHLDVMAGVAGACA
                     VVAGLPEGATEAGRHALRALAGRLMSTAVEVEGGALVWETGAERARLGGFSHGASGVGW
                     ALARTAGVLGDDAIADAAVRALRFDDALFDPSRRRWRDARPEARSAAGSFPAHWCHGTA
                     GIAMARADAAATLDRPDLLELALVGARETASDALPSDDSLCHGTLGNLIAVRGATRRTG
                     VDTGLAEFRDRALQRVLRAGPRSGLPQGVTSVRGLMLGTAGALYALCRELEPGIPDALL
                     LEGPR"
     gene            complement(13227..14543)
                     /locus_tag="CMM_RS10585"
                     /old_locus_tag="CMM_1969"
     CDS             complement(13227..14543)
                     /codon_start=1
                     /function="FOG: Glucan-binding domain (YG repeat)"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490609.1"
                     /locus_tag="CMM_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1969"
                     /product="DUF2510 domain-containing protein"
                     /protein_id="WP_012038656.1"
                     /transl_table=11
                     /translation="MPDVPSAAPAGWFPDGSGQLRYWDGSTWTSHVAPMVQPAAASAFA
                     PSAAATAAVAASQQADAVRNAQAAEAAHDKAMRAAEAAQAKAVRAAEAEQQRVAKVAQR
                     EAAMQAKAAERDAVARDKSARAAAATAATPVPLPTRQRATAAPVAPAAPTAVITDTRPS
                     RHPATTWVITSVVALTVLIITALGGFGGMFVSLGLVGIATALYPYATGRRSWIPILTTR
                     SRNGVAALGAAVLIVIGATVPVAASAPAPRQADAISATASPIPAASPTPSATPTPVVHV
                     VEDVNTKSATDARALLREAGYVVQYVLESGEATAVTDGMTVKSQSPVAGSRTDAGSTVT
                     LTLLAPAPTPTPTPEPTVAPTVAPAPQPAAPAPAPVAPAPAPAPAAPAPAPAPAPGRTI
                     TPGAFCKKTEVGSVEKSDTGKSYRCGPDADGQRNRWYPM"
     gene            complement(14673..15137)
                     /locus_tag="CMM_RS10590"
                     /old_locus_tag="CMM_1970"
     CDS             complement(14673..15137)
                     /codon_start=1
                     /function="DNA G:T-mismatch repair endonuclease"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013583337.1"
                     /locus_tag="CMM_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1970"
                     /product="very short patch repair endonuclease"
                     /protein_id="WP_012038657.1"
                     /transl_table=11
                     /translation="MSRASSDTSRRVMRSNMRRDTAPELAVRRILHAKGMRYRVDFRVV
                     RETRSRADIAFTRQRIAVFIDGCFWHSCPEHLHLPKANADYWIPKLARNVERDAEVAAV
                     LRGLGWTVLRFWEHVPAQDTADRIIVAVERARESASRAGHPRHADVDGSQ"
     CDS             complement(15192..15332)
                     /gene="allorf_2226592_2226732"
                     /locus_tag="allorf_2226592_2226732"
                     /protein_id="allorf_2226592_2226732"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRERNPLHTGCSALRTSVARSAELEGRPARRNAVSRATATGYWSS
                     A"
     CDS_motif       complement(15303..15332)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRERNPLHTG"
                     /locus_tag="allorf_2226592_2226732_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15192..15302)
                     /prepeptide="core"
                     /locus_tag="allorf_2226592_2226732_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="3648.0"
                     /monoisotopic_mass="3645.9"
                     /core_sequence="CSALRTSVARSAELEGRPARRNAVSRATATGYWSSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRERNPLHTG"
                     /leader_location="[15302:15332](-)"
                     /alternative_weights="3666.0"
                     /alternative_weights="3684.0"
                     /alternative_weights="3702.1"
                     /alternative_weights="3720.1"
                     /alternative_weights="3738.1"
                     /alternative_weights="3756.1"
                     /alternative_weights="3774.1"
                     /alternative_weights="3792.2"
     misc_feature    complement(15193..15208)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    15245..15259
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 27.18"
                     /tool="antismash"
     gene            complement(15347..16612)
                     /locus_tag="CMM_RS16290"
                     /old_locus_tag="CMM_1971"
     CDS             complement(15347..16612)
                     /codon_start=1
                     /function="putative hydrolase"
                     /inference="COORDINATES: protein motif:HMM:NF012955.4"
                     /locus_tag="CMM_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1971"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_012038658.1"
                     /transl_table=11
                     /translation="MSTKIEFSRTQWASGQGFFHSGRVAIAGASFLYVYDCGSFDLSAM
                     SREIDAFLNRYHAPIDVLFVSHFHYDHVSGLPYLLRAGVVRSLVLPLIPESDKVIALCH
                     ALASGVTPEAWYLRFLANPRLGIQELDPECEIYELQPQLPSDDPDDDDDASDVEDAHVD
                     SDNLVYGDLLDAPPEGRSREEVHEAPRFDRGESPSVVASSQAGAEVPVWIFKPLLTSFA
                     AKRTETFLSCLAKTLGVTPKKLSRMLASSSELEELVATRADDMIDAYLAVFPDLNLTSM
                     LLYSGPSSHFSSQGVNYRSRSTVERGEVNAWSMRPAWLGTGDQKIGSRRSTEVAKFYGQ
                     LLGRVGTLALPHHGSSGSFHPRLMRYLDMSRIVSVVSVGAKNGYGHPHSEVMRHVSSAG
                     SHIVIVTDDEASRWTEAAVCYL"
     misc_feature    16634..16652
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     CDS             complement(16655..16747)
                     /gene="allorf_2228055_2228147"
                     /locus_tag="allorf_2228055_2228147"
                     /protein_id="allorf_2228055_2228147"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPRSRRLAPSGDLVGDTVMFASMGICASRS"
     CDS_motif       complement(16685..16747)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPRSRRLAPSGDLVGDTVMFA"
                     /locus_tag="allorf_2228055_2228147_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16655..16684)
                     /prepeptide="core"
                     /locus_tag="allorf_2228055_2228147_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="857.0"
                     /monoisotopic_mass="856.4"
                     /core_sequence="SMGICASRS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPRSRRLAPSGDLVGDTVMFA"
                     /leader_location="[16684:16747](-)"
                     /alternative_weights="875.0"
                     /alternative_weights="893.0"
     tRNA            complement(17046..17119)
                     /anticodon=(pos:complement(2228483..2228485),aa:Pro,
                     seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CMM_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CMM_tRNA_0033"
                     /product="tRNA-Pro"
     gene            complement(17046..17119)
                     /locus_tag="CMM_RS10600"
                     /old_locus_tag="CMM_tRNA_0033"
     gene            complement(17193..17732)
                     /locus_tag="CMM_RS10605"
                     /old_locus_tag="CMM_1972"
     CDS             complement(17193..17732)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490611.1"
                     /locus_tag="CMM_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1972"
                     /product="hypothetical protein"
                     /protein_id="WP_012038659.1"
                     /transl_table=11
                     /translation="MDQLLSRLDRIAAGREAGHVIAEDMRDHPWTARAFRWIRWILIAE
                     TIVGATAVAIALTLAEDGVAIAPAVWFRSFVVLAMTLTLYYFAWRASAGYWWAYSRLRL
                     FSQIFPIVTLVIAAIPGLYPLWMVIEQIVFSLLLIGVADILRSDHMRDAFPKPGRVAAP
                     AAPDPSAPGHPGGAPA"
     misc_feature    complement(17706..17720)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    complement(17716..17731)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.44"
                     /tool="antismash"
     gene            18019..19350
                     /locus_tag="CMM_RS10610"
                     /old_locus_tag="CMM_1973"
     CDS             18019..19350
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /function="Acyl-CoA dehydrogenases"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490612.1"
                     /locus_tag="CMM_RS10610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1973"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_012038660.1"
                     /transl_table=11
                     /translation="MTLIDREPRPASGSPAPAHGTANANAPADRPRPAPLGDAPVDRWK
                     GAPRPTTPAAWIARAREVADILAVDQVERDRAGASPQQEVALLKHAGLVTLLGPAEHGG
                     GGQTWDTAYKVIRAVARGDGSIGQLLGYHYLWAWAARLVGTDAQIEAVEKLATTGNLLF
                     GGAVNPRDSDLVIREDGDDLIFSGRKSFSTGGVVSDLTVLEGVIEGTETHVFAIVPTDQ
                     PGIVFGHDWDSLGQRLTESGSVEIRDVRVPWTDAAGFVDKVFQPLVYGTLNVPAIQLVF
                     ANFYQGIAEGALETAAAYTRNTTRSWPYGGDDKERATDEWYVLEGYGQLQSKVWASEAL
                     LDRVGAEISAVLHAPREKLTERKRGEIAVRVAAAKARIAEDGLEVGTRILELTGARASS
                     SKAGLDIFWRNLRTHTLHDPIPYKRREVGRHVLLGEIPEPTWYT"
     gene            complement(19464..20972)
                     /gene="der"
                     /locus_tag="CMM_RS10615"
                     /old_locus_tag="CMM_1974"
     CDS             complement(19464..20972)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /function="Predicted GTPases"
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012038661.1"
                     /locus_tag="CMM_RS10615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1974"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_012038661.1"
                     /transl_table=11
                     /translation="MADHDDDFPELDSGLHERLSSIDEELASQRAQTLRAGLEDYELDD
                     EDLEVLESATDDPDQVTYLPALPVLAVVGRPNVGKSALINRILGRREAVVEDTPGVTRD
                     RVSYKAEHAGRWFTLVDTGGWEPDAKGINASVAMQAEIAMDLADAVLFVVDANVGATST
                     DEHVVRLLRKTKKTVILAANKVDDARQEPNAASLWSLGLGEPHPVSALHGRGVADLLDL
                     VLKTLPLVSKVAKEEVGGPRRVAILGRPNVGKSSLLNKAAGEERVVVNELAGTTRDPVD
                     EQVEIAGKVWRFVDTAGIRRRMHLAQGADFYASLRTSAALEKAEVAVVMIDVSEVISEQ
                     DIRIIELVLESGRALVLAFNKWDLLDDERRRYLEREIETDLAHVSWAPRVNISARTGRH
                     MEKLVPALETALESWDTRIATGKFNAFLAELTAAHPHPVRGGKQPRILFGTQASSRPPT
                     FVLFTTGYLDPQYRRYIQRRLREIYGFEGSPIIVNMRVREKRKR"
     gene            complement(21012..21740)
                     /gene="cmk"
                     /locus_tag="CMM_RS10620"
                     /old_locus_tag="CMM_1975"
     CDS             complement(21012..21740)
                     /EC_number="2.7.4.25"
                     /GO_function="GO:0004127 - cytidylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /function="Cytidylate kinase"
                     /gene="cmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015490614.1"
                     /locus_tag="CMM_RS10620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1975"
                     /product="(d)CMP kinase"
                     /protein_id="WP_012038662.1"
                     /transl_table=11
                     /translation="MTGDTTPAPDPLEDTLLVDATLNRTVVAVDGPAGSGKSSVSRAAA
                     RALGFDYQDTGAAYRALSWFALESGVDTEDPATVTSLIEGFDYDIAIDPSETRVSVRGT
                     DVTEAIREPRVSAVVSRVARVPEVRHYMVELFRSLMASSDKPGIVVEGRDITTVVAPDA
                     QVRILLTASPEARMSRRSAETSTQSAAAVGESLASRDRADSQVVDFMNAADGVTTIDST
                     DIDFDQTVQAVVDLVHARTD"
     gene            complement(21737..22855)
                     /locus_tag="CMM_RS10625"
                     /old_locus_tag="CMM_1976"
     CDS             complement(21737..22855)
                     /EC_number="1.3.1.12"
                     /GO_function="GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012298649.1"
                     /locus_tag="CMM_RS10625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CMM_1976"
                     /product="prephenate dehydrogenase"
                     /protein_id="WP_043560877.1"
                     /transl_table=11
                     /translation="MSEAAGAAAATDTRVQGTVRIVGTGLLGTSIALGLRARGVDVVLA
                     DASPTTLRLAADMGAGRIADIGAAPDRPSLVVVCVPPDVTARVVAAELAAHPDALVTDV
                     ASVKAAPLAELAAMGADLSRYLGSHPLAGRERGGPVSATGDLFLGRPWVIAGHDGITYA
                     AGAPVEQLILDLGAVPIEMTAEEHDASVALVSHVPQVVASLLASRLADGDAAALGLSGQ
                     GLRDTTRIASSDAALWVQILGANASRVVPILRAMRRDLDDVIDALDDVDAQGARLRVAE
                     RIHAGNAGVARIPGKHGQDRRFAAVTVMIDDRPGQLAALIDDVGAADVNIEDLRLEHSQ
                     GAQVGLVEIAVLPEARDRLVARLEERNWRIAG"
     misc_feature    complement(22964..22978)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(23063..23077)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 ccgcgtgtag gcggaggccg gcgacgcgag cacgcgcgcg gccggtcccg tctcctgcac
       61 gcggccgcgc tgcatcacga ccacctcgtc ggcgcgctcg gcggcgaccg ccaggtcgtg
      121 cgtgatcatc agcagccccg cgccggtctc ctcgcggagc cggtcgagca ggtcgagcac
      181 gcggcgctgc acggtcacgt cgagggcgct cgtgggctcg tcggcgatga tcagctccgg
      241 ctcgagcgcg atcgccgcgg cgatgagcac gcgctggcgc atgccgccgg agagctcgtg
      301 cgggtgctgc cgggcgcgcg tctccgggtc gtcgatgccg acgcgctcga ggaggtcgag
      361 cacgcgggcg cggttccgac ggcggtcgcg ggatccgtgg atccgcagcc cctcggcgac
      421 gctcgccccg atggtggcca cggggtcgag ggagctgccc ggatcctgcg gcacgagccc
      481 gatgcggcgc ccgcggatgc cgcgcagccg cgactccccg atgccgacca gctccgtgcc
      541 gccgagcgcg atgccccctc ccgcgatggt gccgttgcgg gcgaggagcc cgaccacggc
      601 ctgcgcgacg gacgacttgc cggacccgga ctcgccgacg agcgccgtga cacgccccgc
      661 ggtgatctcg aaggagacgc cgtcgaccgc gcggcgggtg cccgccgccg tccggtagtc
      721 cacctgcagg tcgcgcacgg cgaggagcgg atgcgtggga tcggtcatgc gagctgccct
      781 ccgcggatcg actggctgat gcggttggtc gcgagcacga cggccacgac cacggcgccc
      841 gggagcaccg tgagccacca cgcggtggcc acgtagtcgc ggccctccgc gacgagcagg
      901 ccccactcgg gcgtgggcgg cggggcgccg tagccgagga agccgagcgt ggagatctgc
      961 aggatcgcgg atccgaactg gagggccgcg agcgcgatca cgggcgtgag cgagttcggc
     1021 agcacgtgcc ggcgcagcac ctgcacgagg gtgccgccgg atccgtacgc cgcctcgacg
     1081 tactcgctga tccgcacgcg caccacctcc gcccgcgaca gccgcgcgaa cacggcgatg
     1141 gacgtgacac ccaccgcgat cgcggcgttc gtggtgccga agcccagcag gatcacgatg
     1201 ctcaagctga gcagcaggcc cgggatcgcg agcagcacgt cgacgagccg catgagcacg
     1261 tcgtcgacga tgccgccgac cgtgcccgcg accacgccga ggagcgtgcc gacgacgaga
     1321 ccgacgagca ccgcgacgac cgcgccgacg accgactgcg acgccccgaa cacgacgcgc
     1381 gtgtagaggt cgcggccggt ggagtcggtg ccgaaccagt gcgcggcgct cggcgcctgc
     1441 agcgacggcg ccacggacgc ggtcgggctg ccggacgcga agaggccggg gacgagcgcc
     1501 cacagcagca tcacgagcac gacgaggaca gggatcacga ggccgcctgc gaggcgcgcc
     1561 cggctgcggg gacgcgcgcg gggcgcgtcg atggtggcga gcgtggcgct catcgcgcac
     1621 ctcctctgcg caggcgcgcg tcgagaacgg ggtagagcag gtcgaccgcg aggttgatca
     1681 cgacgtaggc gaccgtggag agcacgacga ccgcgagcag caccgggctg tcgcggctcg
     1741 cgaccgcctg cacggtgagc tggccgacgc ccgcgcggcc gaagacggcc tcggtgacga
     1801 ccgccccgcc gacgagctcg ccgaacagca gcccggccat cgtcagcgtg ggcagcagcg
     1861 cgttccggcc gacgccgtgc agcagcagcc acggcgtgtc ggcgccgcgg gcccgcacca
     1921 cctcgacgaa cggcatggcc gacacgtcgt cgatgctgcg gatgagcacc tgcgcgagcg
     1981 gcgccgcgat cggcacggcg atcgtgagca ccggcaggat cagcgcctcg ccggggctcg
     2041 cgccgatgat cggcaccagc ccgagccgga acgacagcac ctggatgagg atgatcccca
     2101 cccagaacac gggcagcgag acgagcagcg gcggcaggtc gcggaagacc cgacggatcc
     2161 acctggcacc gccgtacgtc gcgaggaacg cgatcggcac ggccagcacc acggcgacca
     2221 ggaggccgag caccgcgagc acgagcgtcg acgggatcgc ggtggcgagc agcgtcgaca
     2281 cggccgcgcc gctctgcacc gagtacccga gctgcccctg cgcgaacgcg gcggcggact
     2341 cgccgagccg cacgatgagc gggcggtcgg cgccgtacga ctcgcggatc gccgcgagct
     2401 gctcgggcga gaggccgagc tcggggccgc cgtagcgggc gagcaccgcg tcgccgggca
     2461 gcgcggcgag cagcacgtag gccacgacgt aggcgaggac gagcacgatg acggcctgcc
     2521 cggcgcgccg gatggcgtag ctcatcgcgg tcccccgccc gtcgacaggg gaaggacgcc
     2581 ccgcatcagc ggtcgagcca gacgcccgcg aacactgggc ggccgaccga ctcggtggcg
     2641 aagccccgca cgtcgccgcg gaggccgtag acctggggct cctcgaacag cggcagcacg
     2701 taggcctggt cggcgatgcg ctgctgggta gcggcggacg cggcctggcg gccctccgtc
     2761 gtgggctccg acgcgatgcg ggtgaggagc gcgtccagct ccgggtcggc gatgctgccg
     2821 tccgcggggt tccggttgag cagcacgttg cggttggtgg aggagtactg cgacttgagg
     2881 acgtcgtagt ccgagcggcc gaccatcgag tggtacgcct cgagcgcgtc cgggtcctgc
     2941 gaggccttcg tctgcgcggc ctggtcgccc gagaacagct ccacctccac gccgatctcc
     3001 gcgagctgcg actggatcag cgtcacgacc tccttggagc gcggctgcgg gagcgcctcg
     3061 ttgacgacga gctccagctt ccgtccgtcc ttctggcgga tgccgtcgga tccggggacc
     3121 cagccagcct cgtcgaggag cgcggcggcc ttgtcggcgt catgcgcgta gtacgaggag
     3181 gtgtcgacgt agccgagcgc gctcttcgcg agcacgccgg tcgcgagcgg gtagctgtcg
     3241 ctgaagaggg tgtcgaggat cgcctgccgg tcgacgcccg cgatgatcgc ctgccggacg
     3301 cgcacgtcct cgagctgcgg cgtgcggaag cggaggttga tgccgttgtc gacgccgttg
     3361 gtcgccgccg cgacgagctg gaggtcgccc gtgcggaact gcgcctcgtc gggcgcctcg
     3421 atctgccggg cgacgtcggc ctgcccggcc acgaccgtgc cgacccgcac gctgtcctcg
     3481 gcggcgacga tgaggtccac cccgtcgacg agcggccggc cctggtgggc ggcctcgggc
     3541 ggcgcccagt cgtagtcctc gcgggcggcg agctggatct gcgtgcccac cgactccccg
     3601 gacaccgtga acggcccgct gccgatgacc gtctccgcct gcccgggccc gaaaccgtcg
     3661 tcggccttgg cgagcgtcga gtcggacacg agccccgagt tgatggtcga ggtggcctgc
     3721 gcgaagccgg gcgcgggagc cgtgaagtgg aacctgacgg tgtccgcgtc gacgacctcg
     3781 ccgcggtcgt agttgttgat cgcctcgctg acggtgagcg ctcggtcgac gtcgcccttg
     3841 ccgtagaggt cgaagttcgc gacgacgttc tgggcggtga gcggggtgcc gtcggagtag
     3901 gtcacgtcgg tgcggatgtc gaacgtgtac tcggtcgcgg cggcgttcac ctcgggcagc
     3961 gccgtcgcga tccacggctc gagctcgagc gtctccgggt cctgccagag cagccggtcg
     4021 gtgatgttgt tgacgacggc gccgttcggg tagaagccgg cggccggcgg gtagagcgtc
     4081 gtccaggtct gcggctcgag gtaggtgagc gtgccgccgg ccttcggttc gccgctcgcc
     4141 gcttgatccc ctccgccgcc cgccgagcac ccggccatca gaccggtcgc cgcgacgagg
     4201 gcggtgaggg cgatgacggg gcggggagga cgaggcatgg ttctgctcct gcgtgtgctg
     4261 tgcgtggatg ggtgagacga ctccaacacg catgcagggt cttcgcaggg ccgcggaaca
     4321 tgcggcgtaa cggggtgcaa cgcggcgtca cgcggggaat gccacccgcg tgctcgccgt
     4381 tgcggcgccg gcgtgacgcc tcgccgccgt cggctccgct gccggatgcc gacgccctct
     4441 agggttccgg gatgaccacg caccccaccg tccgtcccgc cgtgcccgac gacgccgacg
     4501 ggatcgccga ggtccacatc cgcacctggc aggagacgta cgcgcacctg ctgccggccg
     4561 tgtacctcga cggtctggac gtcgcggcgc gcgccgagca gtggcggggc tcgctgggtg
     4621 acgcttccgg ggctccgacc gtcgtcgccc tcgacgacga ccgcatcgtc ggcttcgcgc
     4681 tcgcgggacc ggcgcgcgac gaggatccgc cgcgcccctt ccagctctac gcgatcaacg
     4741 tggtcgcgtc cgcgcacggc acgggcgccg gccaggccct gttcgacgcg gccgtcggcg
     4801 actcccccgc ctacctctgg gccgccgacg acaacccgcg cgcggcggcg ttctaccgcc
     4861 gcaacgggtt cgcgcgcgac gggggcgtcg agcggcagac gtaccagggg gcggagatgg
     4921 tcacggtgcg gatggtgcgg tgaggatgcg ggcgcgaggc ccgcggaccg acgcgccgct
     4981 cagcggagct tgaccacgcg gatagccgcg agggtgagga ggacgacgag cgcgccgagg
     5041 cccacgctcg tcgcgaggag cggcagggtg tccgccgtcg tgaggccccc ggatcccgcg
     5101 atcgccgtcg accccaggtt cagcgcccgg gtgttgatcg cctgcgggag cacctccgcc
     5161 agcggacgca gggccgccga ggtcacggcg gcgacgcccg cgacgcaccc gacgaggcac
     5221 agcgcgaccg gcgccgcgaa ggaccgcagg agcagcgaca gcagggactg gacggcgatg
     5281 aggggcagcg ccgccacggt cgcgatcagc cccacgagga ggaacgcgac ggggaacggg
     5341 ccgtccagcc ggagcacgaa cagcccggac accgccgtgc cgccgacgag caccgcctgc
     5401 atcagcgcca ccggcacgag gatcgccacg atcttcgcca gcacgagtcg gatcggtcgc
     5461 gcggtcgccg tcagcagggc gttccagttg gtgccgcggt gctcgacgcg ccagatggcc
     5521 gccgcgagca ggctgatgcc catcgagtag aagagcaggc cgtagaacag caccacctgc
     5581 gaggtgaagg acgcccaccc ggagtccagg gtctgcgtgt tgttcgccag gttgatggtg
     5641 ccggtgacga cggccaggag cggcagcagc accgcgatga tccagatgct ggagcgcttg
     5701 agcttcacgg cctcggctcg gaacacgccc gtcacctctc cacgcggtcg agccggatcg
     5761 tcgcgagcgc gaaggccgcc gcgaccacga cgaggaagcc ggcgatccac ccgagcggcg
     5821 aggcgacgta gcccacgccc gcgtccgact ggccggcctg cgagatgacg gcgtagtacc
     5881 cccacgggat ggcccggctc gcgacggacg ggagcaggag ggagaagacg gccaggaagg
     5941 cgcccagcat ccccacgccc acgctgatga gctggttctc gacgcgcgcc gcgagccaga
     6001 cgtgcagcgc gcagaacgcc acgtcgacca ggtagagcag gagcgtgtac agcgcccacg
     6061 gccccacctc gacgggcacc cggatcccgg cggcgtaccc ggcggcgatc acgagcagcg
     6121 attggatcag cacggcgggc acgaggagca ccgcgagggc cacgagcttg gcccggcaca
     6181 gctcccccgc cgtgcgtccc gcgcccgccg cgaggatcca cccgcccgcc tggtgctcga
     6241 tgtcggtctg gcggctcgcg atcaccgcgg tgaggatcgg cgaggtcatc gccgccatga
     6301 gcgtgtagcc gagcaggagc gcggcccagg ggtgcgcgcc cggatcgtcg aagcccgcac
     6361 gcgtgctgcc cgcgaactgc gacgccgagc tcagggcggc gacggccacc accatgccga
     6421 tgagcagcgg gagcgagcgg agccggtgca tcttgcggaa ctcgatcgcc acggcgcgcc
     6481 tcacagctgc cccccgcgcc cggtgatgtc catgaacacg tcctccaggc tctgcggcag
     6541 ccgccgcacc tcgtgcacgg gcacgtcggc cgccacgagc cggcgcacga tgtccgcggt
     6601 ctcgtccttg gagcgggcgc tgagccggat cccctccggg ctcctggccg ccccggcgac
     6661 ctccgccatg gcccggtccg gcgcggacgt ctcgatgacg aggtcgggga tggagtgctc
     6721 gaacagctcg gcgcgcgtgc cctggaagat catccggccg tcggccagga tgccgagcac
     6781 gcccgccatc ttctcgatct cgtcgaggag gtggctggag accatcacgg tgatgccctg
     6841 gccggccagg tccatgagga gggagcggac ctcctcgatg cccgccggat ccagcccgtt
     6901 ggtgggctcg tcgaggacga gcagcgaggg gtcgcgggcg agggccatgg cgatccccag
     6961 ccgctgcttc attccgagcg agtaccggcg caccagcttg tcgcggtgct gcgtgagccg
     7021 cacggtcgcg aacgcccgct ccacctgggc ctccgcgagc ccgagcatgt cgcgcacgat
     7081 ccgcatgttc tcccaccccg tgaggtggcc gtagccggcg ggcgcctcga tcatggagcc
     7141 gatggacggc aggagcccgc cgcgcgtcgc cggcgtgagc cgctggccga acaggtggat
     7201 ctcgcccgac gtgggctgcg tgagcccgag cagcatcttc atggtcgtgg acttgccgga
     7261 gccgttgggc ccgaggaacc cgtacacgga cccctgcggc acctcgatgt cgagcgcgtc
     7321 gacggcgacg tgatcccgga accgcttggt gagcccgcgg gtggcgatga cggcgctcat
     7381 cggcgcgggg gtgtcgtggt cggcatgccc ccatactcgg ccggccgccg cgcgggcgca
     7441 tcgtgccgtg ggccggtccc gcccggtccc ctctcctgcg atgggaggag cgggtggcag
     7501 gtcggcggga ccgcgcccca tgcgccgcag cggtcaggcg gcgaggcccc gccggtgcgc
     7561 ccagatcacc aggtggacgc ggtcgcgcac ggcgagcttg gtgaggatgt gcccgacgtg
     7621 cgtcttcacc gtgacctccg cgatggacag gtcgcgggcg atctccgggt tggacgcgcc
     7681 cgtgacgagg cgcgtgaaca cgacccgctc ccggtcggtc aggacgtcga gcgctgcggt
     7741 gtccgggtcg ggcggcgccg tcctctcgac ggccagccgc tcgaggagcc gctgcgtggt
     7801 gctcatcgag gcggcgaacg tgccgttgtg cacggaccgg atcgcgtcga ccagctgcac
     7861 ggcggtgctg tccttcagca ggaagccgac ggcgccggcg cgcagcatcc ggatggcgta
     7921 ggagtccgtg tcgtgggtgg tgagccccag gatccgcgtc ccctcggcgc gcccgccctc
     7981 cacgagccgg cgggtcgcct cgatgccgtc gaggaccggc atgcggacgt ccatgagcac
     8041 cacgtccggg cggagctcga cgacgcgggc gacggcctgc tcgccgtccg cgcagacgcc
     8101 gaccgcggcc atgtccggct gcgcgtccac gatgcgggcg aagccgtccc gcacgaggga
     8161 ctggtcgtcg accacgacga cccggatcgg cgcgggcgcg tcggtcacgg ggtgctcccg
     8221 ccgagcggcg cggtcggcca ccgcgcctgg aggacgaact cgtcgtcgca cgcgtaccgg
     8281 gcctgccctc cgtagagcgc gcagcgacgg cggatcgcgg cgaggccccg gtgctcctgc
     8341 acggggcatc cccgcttgtc gcgaaccacg gcattggcga cggtgatcgc cagcgcgtcg
     8401 ggcgaccact cgacgcggag gcgcgcggtg ccgcccgcgc cgtgccgcat ggcgttcgtg
     8461 agggactcct gcacgacccg gtagacggcg aagcccacgc ccggcaggag gggtcgcggc
     8521 gagcccgcgt cctgcctgtc gatgccgagg ccggagccgc ggaagccctc gacgagggcg
     8581 tcgacgtcgt cccagccggg gatgggacgc acgtccgcgt cggcgtcggt gggcgcgagg
     8641 agcccccgca cctcgtgcag ggcggcccgg ctggtctcgg agatggtgcg gaacatgcgc
     8701 gacgcctcgg ggctcggcgc ggtcgcccgg ccgctctccg cctggacgat gacgctggtc
     8761 agagtgtgcg ccagcacgtc gtgcatgtcg tcgctgatgc gctcgcgctc ctcgtaggcg
     8821 gcgagccgcg tccgggcgtc cgcgtcgcgt tcggacagcg tcgtccggag ctcggcggtg
     8881 cggacggcct cgctgcggcg ccgttcgagc agaccggccg cccatgcgac cgcgaagctc
     8941 acggacacga gcgcgatgac catgccgacg gatcccgtgg agcccagctc cccgccggtg
     9001 agggtgcgcg cggcgaggac gaccacgaag cacgcgccga gggcgaggcc gacgtgccgg
     9061 agccggtccg cggcgtgggc ggcgacggag taggccgcca ccaggagcac gacgtcaccc
     9121 gggaacagga gcgagctcgt ggcgagcatg tgcgccgacg agatcgccgt ggccagcagc
     9181 gcggcggtga cgggccgcgc gtggcgcacc gcgagcgtga gcgccatgag ggacgaccag
     9241 atccagtcgg gctggcccag gacgcccatg atggcgcaca ggacgacggc agcgcccgcg
     9301 acgacctggt cgccttgcgc gcgcagactc ccccgtcgca tcacgtcctc aggctagcgg
     9361 ggaggacacg cccggccgcc ggcggacgcc ctccccccgg ccccccgtcc gcggggcatc
     9421 ccggtcgcgg cctccgacga tgggcggagg gcacggccgc ggatgtcatc gggtcgcacg
     9481 atgcgctcgg acggaagccg ctgggaacgt gaacaccagg gatcgcgcat gggctgcgcg
     9541 tcgacgccgc accggccgag gcgcacggat ccgcgatccc cacggggcaa gtcggacctg
     9601 tgacggccca tgggccatcg ggatgggtgc ggctcgcacc acgacggtct gggccgaccg
     9661 gccgggatcc atgcgcgaca acaggaacac aggtggaaca cgatgaacga catcctcgag
     9721 acggagaccc ccgtcatggt cagcccccgg tgggacatgc tgctcgacgc gggcgaggac
     9781 accagcccgt ccgtccagac ccagatcgac gcggagttcc gtcgcgtcgt gagcccgtac
     9841 atgtccagca gcggctggct ctgcacgctc accatcgaat gcgggacgat catctgcgcg
     9901 tgtcgctgac ggacgccctc gacggacggg ctgcgctcgg cgcgcggtcc gtccgctccg
     9961 cgtcgggccc cgcccgccgg agcggcgagg gggatccgac gtgacgatca ccgcggccga
    10021 gctctcgctg ctgcaggcgt cccggctgcg cgaacggcgc gcggcgacgc gggccgatgc
    10081 ccgaccggtc cccgagctga cgcgcgcctg gcgcgacgac gccctcgtcg acgacgggac
    10141 gcacgccgcc tacctcgccg ggcagctgct ggacggcgac gacctcgtgg cgctcctggc
    10201 gggcgacgcg tggaccccgc gggccgcgag cgcggactgg ctcgcccggg tcgacccctg
    10261 gctcgtgcat ccgcctgtct ccgcggaggc ctacgcgacg gcgaacggcc acctcgtcgt
    10321 cgaggacacc cgcgtggccg ggctcccctt cgccgccctg ctcggcccga tggtcggcgc
    10381 gcagcgcgcg cacctggacg gtcgcccgtg gctctcgcgc accgcgaccg cggatctcct
    10441 cgacggcctc gcggagcgcc tcgcgaccct ctccctccgg gccctcctcg cggagctcgc
    10501 ccgggatccg gcaccgggtc ggcacgcgcg gctggatgcg cggctcgccg accccgagca
    10561 ccgcgccgag ctcctctccc gccaccccgt cctcgcgcgc gacctcgtca cggcgatcgg
    10621 cagctggcgc gcgcacgtcg cgcgcatcct cgaccgcctg cacgccgacc acggcgacct
    10681 cgtccggatg ggcctcgcga ccgagcggct cgacgccctg gaggccgtgg acctgagctc
    10741 gggcgacccc cacgacggcg ggcagtccgt cgcgacgctg cgcttctccg acggcagcct
    10801 gctcgtctac aagccgcgcg actgccgggt gttcgcgctg taccgcgacc tcgtcgacgc
    10861 gctcgcgccc gccctccccg gcgagatccg cctgcgcgcg gccgcggtgc tgccgcgcga
    10921 cgggtacggc tgggtcgagt tcgtggccca cgccgaggac gccgcctccg cgatccccct
    10981 gtcccggcac ctcggccggc tcggctcgct gctcgccgtc gcgcacgtgc tcggcgcgtc
    11041 cgacctccac ctcgagaacg tcatcgcctc cgcggacggt cccgtgccca tcgacctgga
    11101 gacgctgatc cagaaccgca gcgaggtcga cggcgaggac gggacggccc tgcgccgggc
    11161 gtcgcggatg ctcaacgcgt cggtgctggg cagcggcatc ctcccggtcc agctcaccac
    11221 cggggagggc acgagcatcg acgtcagcgt cagcaccggg ggcctgcacg gcgcggggac
    11281 cacggcgacc gtccaccagg tggtggacgc ggccacggac cgcatgcgca tcgaggcgcg
    11341 cgagatgccg gtcggccggt cgcgcaacca gccgccggga gcgacgctcg cgcgcatccg
    11401 ctccggtcgc gccgccctcg cggacgggta cgagcgcacc ttccgcgcca tcgtcgagcg
    11461 ccgggcggag gtccgcgcga tcctgtcggc cgcgcccgac atctcgtcgc ggcacatcgt
    11521 gcgcgccacc cgctcctact ccctgctcct cacggagatg cgccgacccc gcccgctccg
    11581 cagcggcatc gaccgggacc acctcctccg ccacctctgg acgcgcgtcg aggagcatcc
    11641 cgcggatgcc gcgctggtcg aggcggagga gcgcgccctc tggcggctcg acgtgcccct
    11701 gttctccacg cgcatggacg cacgcgccct catcgccgac gacgaggagg ccgggccgca
    11761 gcgcttcgcg cggagcacgc gcgaggacgt gctcgaccgg ctcgcgcggc tcaccctcga
    11821 cgacctcccc gagtccctcc ggctggtcga cgagtccgtg ctggcggcga ccgcgacgcc
    11881 cgacggagac gacgacgccc gcgacgacgc gcgaggacgg caggccgcgg acgccaccgc
    11941 ctcgctggcc cgcgcaccgc gggtggacga cgacgccctg cgggaggcgg cacgcggaca
    12001 ggcccggatc ctcctcgcct ccgccgtcct cggccgggac gacgcgacct ggatcggcgt
    12061 gagcagcagc ctcgacagca gcggcctcga gtaccgcccc gcggggccca ccctgtacga
    12121 cgggctggcc gggatcgcgt tcgccgcgac ccacgcgcac ggcgtgctgc ccggcctcgg
    12181 gctcgacgac ctggccggcc gggcgatgca cgcggtcacg gcgatcctcg acgactggac
    12241 gcgcggcctg atcgacctgc cggtgggcgc ctacagcggc gcgaccgggc tcctccacgc
    12301 gctcgcccac cacgacgcgc gagtcggcgg agacgggcac cgcgacctcc gggcggcggc
    12361 cgtccgacgg ctcggcgagg tggcccacga ggatccgcac ctggacgtga tggcgggcgt
    12421 cgccggcgcg tgcgccgtcg tcgcggggct gcccgagggc gcgaccgagg cgggccgcca
    12481 tgcgctgcgc gcgctcgcgg ggcggctgat gagcacggcg gtcgaggtgg agggcggcgc
    12541 cctcgtctgg gagaccggtg ccgagcgggc gcggttgggc gggttctcgc acggcgcatc
    12601 cggcgtcggc tgggcgctcg cccgcaccgc cggcgtgctg ggcgacgatg ccatcgccga
    12661 tgcggccgtc cgcgccctgc gcttcgacga cgcgctgttc gacccgtccc gccgccgctg
    12721 gcgcgacgcg agaccggagg cgcgatccgc ggccggatcc ttccccgcgc actggtgcca
    12781 cggcaccgcc ggcatcgcga tggcacgcgc ggacgcggcc gcgacgctcg accggccgga
    12841 cctcctcgag ctcgccctcg tcggcgcgcg cgagacggcg tcggacgcgc tcccctccga
    12901 cgactccctg tgccacggga ccctcggcaa cctcatcgcc gtgcgcggcg cgacccgacg
    12961 caccggcgtc gacaccgggc tcgcggagtt ccgcgaccgc gcgctgcagc gcgtcctccg
    13021 cgccggcccg cgcagcggtc tgccccaagg ggtgaccagc gtgcgggggc tcatgctcgg
    13081 cacggccggc gcgctctacg cgctgtgccg ggaactggag ccggggatcc cggacgcgct
    13141 gctgctggag gggccgcgct gacggtcgcc ccggttgttc gcgcggggtg gcccgggcag
    13201 ccgtcgtggg gccgcccggg agtcggtcac atcgggtacc agcggttgcg ctgaccgtcg
    13261 gcgtccgggc cgcatcggta gctcttgccc gtgtcggact tctcgacgct gccgacctcg
    13321 gtcttcttgc agaaggcacc gggcgtgatc gtccggcccg gggccggggc aggggcggga
    13381 gccggggcgg caggagcagg cgcgggagca ggcgcgacgg gcgccggagc aggagccgcc
    13441 ggctgcggcg cgggcgccac cgtcggcgcg accgtgggct caggcgtcgg cgtcggcgtc
    13501 ggcgcgggcg ccagcagcgt gagcgtcacg gtggatccgg cgtcggtacg cgatcccgcg
    13561 accgggctct gcgacttcac ggtcatgccg tcggtgacgg cggtcgcctc acccgactcg
    13621 agcacgtact ggacgacgta gccggcttcc cggaggagcg cgcgggcgtc cgtcgcggac
    13681 ttggtgttga cgtcctcgac gacgtggacc acaggcgtcg gcgtcgcgct gggcgtcggg
    13741 ctcgcagccg ggatcgggct cgcggtggcg gagatcgcat ccgcctggcg cggagcgggc
    13801 gcggacgccg cgaccggcac cgtggcaccg atgacgatga gcacggcagc gcccagggcg
    13861 gcgacgccgt tgcgcgaacg ggtcgtcagg atcgggatcc agctgcggcg acccgtggcg
    13921 taggggtaca gagcggtggc gatcccgacg aggccgagcg agacgaacat gccgccgaag
    13981 ccgccgaggg cggtgatgat cagcaccgtc agcgcgacga cggacgtgat gacccacgtg
    14041 gtcgccgggt ggcggctcgg ccgggtgtcg gtgatcacgg cagtcggagc cgcaggagcg
    14101 accggcgctg ctgtagcgcg ctgtcgcgtc ggcaacggca ccggcgtcgc ggcggtcgct
    14161 gcggccgccc gggcgctctt gtcccgagcc actgcatcgc gctccgccgc cttcgcctgc
    14221 atggccgcct cgcgctgcgc gaccttcgcg acgcgctgct gctccgcctc cgcggcgcgc
    14281 acggccttcg cctgcgcggc ctcggctgcc cgcatcgcct tgtcgtgcgc ggcctcagcc
    14341 gcctgggcgt tccgcacggc gtcggcctgc tgcgatgcgg cgaccgccgc cgtcgctgcc
    14401 gcgctcggag cgaacgccga cgctgcggcg ggctgcacca tcggcgcgac gtgcgacgtc
    14461 cacgtggatc cgtcccagta gcggagctgc ccggatccgt cagggaacca gccggcagga
    14521 gcggcggagg ggacgtcggg catggtgctc ctcgggtgcg tgccgcgacg aaggggtagg
    14581 cggcaggtgg tgccgtcgag tgacgacgcc tgaggctatg agcgcgatcc gccggccgta
    14641 agccctcgca tgggggtgaa agaggcatgg cactactggg atccgtcgac gtcagcgtgg
    14701 cgcggatgcc ctgccctcga ggccgattct cgcgccctct cgaccgcgac gatgatccgg
    14761 tccgccgtgt cctgagccgg cacgtgctcc cagaaccgca gcacggtcca tccgaggccc
    14821 cgaagcacgg cggccacctc ggcgtcgcgc tcgacgttcc gcgcgagctt cgggatccag
    14881 tagtcggcgt tcgccttcgg caggtgcagg tgctccgggc agctgtgcca gaagcacccg
    14941 tcgatgaaga cggcgatgcg ctgccgggtg aacgcgatgt cggcacggct ccgggtctcg
    15001 cgcaccactc ggaagtcgac gcggtacctc atgcccttcg catgcaggat ccgccggacg
    15061 gccagctcgg gagcggtgtc ccgccgcatg ttcgaccgca tgacgcgtcg ggatgtgtcg
    15121 gaggaggccc tggacatgcg ggcacatcac cacgagctac cgacatcacc ttttcatcga
    15181 ccgatgccgg cctaagcact agaccagtag ccagtcgcgg tcgcgcggct gacagcattt
    15241 cggcgggccg gccggccctc gagctcagca gagcgcgcga ctgaagtgcg cagcgctgag
    15301 caccctgtat gcagcgggtt gcgttcacgc aagagcgtaa atgttgctag agataacaca
    15361 cggcagcttc cgtccagcga gatgcttcgt cgtcagtgac aatgactata tgacttccgg
    15421 cggatgacac atgccgcatc acttcactgt gcggatgccc gtaaccattt ttcgcaccca
    15481 cgctgaccac agaaacaatt cttgacatat ccaagtatcg catcaaccgc gggtggaagc
    15541 tcccgctcga accatggtgc ggcaacgcaa gggtccccac ccgccccagt agctgcccgt
    15601 agaatttggc gacttccgtg gatctcctgg acccgatctt ctgatctccc gttcccaacc
    15661 aggccggacg cattgaccaa gcgttgacct cgccgcgctc tacggttgat ctgcttctgt
    15721 agttgacacc ctgtgaagag aagtgactcg aaggcccact gtaaagaagc atgctagtca
    15781 aattcagatc tggaaacact gccagatatg catcaatcat gtcatcagcc ctagtggcaa
    15841 ccagttcttc aagttcacta ctggaagcca acatgcgaga cagctttttc ggtgtcactc
    15901 ccaaggtctt ggcgagacat gacaaaaagg tctctgtccg cttggccgcg aagcttgtga
    15961 gcaaaggctt gaatatccat acgggaacct cggcgccggc ctgactgctc gcaacaacgg
    16021 acggtgattc tcctcggtcg aacctcggcg cctcgtggac ttcctcacgg gatctacctt
    16081 caggcggtgc gtccaagagg tcaccgtaga cgaggttgtc agagtcgacg tgcgcgtctt
    16141 caacgtcaga ggcatcgtca tcatcgtcgg gatcgtcaga cggcaactgt ggttgcaatt
    16201 cataaatctc acactcgggg tcaagttcct ggatgcctag gcgcggattg gctagaaacc
    16261 gtagatacca agcttcaggg gtcacgcctg acgcaagagc atgacacaac gcgattacct
    16321 tgtcagattc ggggatcagg ggaagcacca gcgagcgcac cacccccgcc ctcaagagat
    16381 acggcaaacc actgacatga tcgtagtgga aatgtgagac aaacaatacg tcaataggtg
    16441 cgtggtagcg attcaggaaa gcgtcaattt cgcgagacat ggccgataga tcaaaggagc
    16501 cgcaatcgta cacatacaga aaagaagcac ccgcgatagc cactcttccc gagtgaaaga
    16561 aaccttgacc actagcccac tgagtccgtg aaaactcgat ctttgtcgac accaatcacc
    16621 cctgattaca gccagatatt atacagtcgg agaactatga gcgtgacgcg caaatcccca
    16681 tcgaggcgaa catcacggta tcgccgacca agtcgccact gggcgctaac cgacgagatc
    16741 gcggcacgta tccatcgatg actagccaaa gatgcgccga atggcactcg cgaaaatcaa
    16801 tgtctcatag acctcgactc ctagccacac ccaatcaggg gggtagggtc cacgacatcc
    16861 actcaccgcc gtcgacgcaa ccgaaaaaca cccatcggtc tgtacgctcg atgtaaccaa
    16921 cggtgtgatg aaatgcgggg aaataatcga cccggtctcc cactgaaggc gaacgcgggc
    16981 atgacggcaa tccggatacg acgaatgccc cggccggacc cataggtcct tccgaggcat
    17041 gtccgtcggg ctgacaggat ttgaacctgc gaccccttga cccccagtca agtgcgctac
    17101 caagctgcgc cacagcccgc tgtcccatcg ctgggcaact cgtagagcct accgcatcgg
    17161 cggcactgct ccggcacgca cgaggccccg gatcaggctg gcgcaccacc cgggtgaccc
    17221 ggagcggagg ggtcaggcgc agcgggagca gccacccgcc ccggcttcgg gaacgcgtcc
    17281 cgcatgtggt cgctccgcag gatgtcggcc acgccgatga gcagcagcga gaagacgatc
    17341 tgctcgatga ccatccagag cgggtagagg cccgggatcg cggcgatcac cagggtcact
    17401 atggggaaga tctggctgaa caggcgcagg cgcgagtacg cccaccagta gccggccgag
    17461 gcgcgccagg cgaagtagta gagcgtgagg gtcatcgcga gtaccacgaa ggagcggaac
    17521 cagacggcgg gggcgatcgc gacgccgtcc tcggcgaggg tcagggcgat ggcaacggcg
    17581 gtcgcgccca cgatggtctc ggcgatgagg atccaccgga tccagcggaa ggcccgcgcc
    17641 gtccacgggt ggtcgcgcat gtcctcggcg atgacgtggc ccgcctcgcg cccggcggcg
    17701 atccgatcga gacggctgag cagctggtcc accggtgcga tcctccgtct ctcgtgagcg
    17761 ggcgtcggat gcgcccggat cagggtacga cgtgacgcct ggagccgccc gcgaacgtgg
    17821 ggagcggcgc gatccggaca ggcgacgcgg gcgccagccg gcggtcggcg gatcccccgc
    17881 atgacggccc gtgacgcccc gcgtcgtcac gcggggacac ccgccgtcac acccctcgcc
    17941 accccgcgcg acccgcccct accgttgccc caccgcgagg cgcggcaccg gtcgcgcccc
    18001 ttcacgagag gacaggacat gaccctgatc gaccgcgagc cccgacccgc atccggctcc
    18061 cccgcgcccg cccatggcac cgcgaacgcg aacgcgcccg ccgaccgccc gcgccccgct
    18121 cccctcggcg acgcgcccgt cgaccgctgg aagggcgcac cgcgtcccac gacgcccgcc
    18181 gcgtggatcg cccgcgcccg cgaggtcgcc gacatcctcg ccgtcgacca ggtcgagcgc
    18241 gaccgcgccg gcgcgagccc gcaacaggag gtcgcgctgc tcaagcacgc cggcctcgtc
    18301 acgctgctcg ggcccgcgga gcacggcggc ggcgggcaga cctgggacac cgcgtacaag
    18361 gtgatccgcg cggtcgcccg cggcgacgga tccatcggcc agctcctcgg ctaccactac
    18421 ctctgggcat gggccgcgcg gctcgtcggc acggacgcgc agatcgaggc cgtggagaag
    18481 ctcgccacga caggcaacct gctcttcggc ggcgccgtga acccgcgcga ctccgacctc
    18541 gtcatccgcg aggacggcga cgacctcatc ttctccggcc ggaagtcgtt cagcacgggc
    18601 ggcgtcgtgt ccgacctcac ggtgctcgag ggcgtcatcg agggcacgga gacccacgtg
    18661 ttcgcgatcg tgccgacgga ccagcccggc atcgtcttcg gccacgactg ggacagcctc
    18721 gggcagcggc tcacggagtc cggctcggtc gagatccgcg acgtgcgcgt gccgtggacg
    18781 gatgccgccg gcttcgtcga caaggtgttc cagccgctcg tctacggcac gctcaacgtg
    18841 ccggcgatcc agctcgtgtt cgcgaacttc taccagggca tcgcggaggg cgcgctcgag
    18901 acggccgccg cgtacacgcg caacaccacg cgctcatggc cgtacggcgg cgacgacaag
    18961 gagcgcgcga ccgacgagtg gtacgtgctc gagggctacg gacagctgca gtcgaaggtg
    19021 tgggcgtcgg aggcgctgct cgatcgggtg ggcgccgaga tcagcgccgt gctgcacgcg
    19081 ccgcgcgaga agctcacgga gcggaagcgc ggcgagatcg ccgtgcgcgt cgcggcggcg
    19141 aaggcgcgca tcgcggaaga cgggctggag gtcggcacgc ggatcctcga gctcaccggt
    19201 gcccgcgcct cctcctcgaa ggccgggctc gacatcttct ggcggaacct gcggacgcac
    19261 accctgcacg acccgatccc ctacaagcgc cgcgaggtcg gccggcacgt gctgctcggc
    19321 gagatcccgg agccgacctg gtacacgtga tccgcagcca gcccccgacg acggacggcg
    19381 ccgaccccgc gagggatcga cgccgtccgt cgtgctgcac gcggcagcgg agagggagcg
    19441 ctagcgcttc cgcgctgtgc cagctagcgc ttccgcttct cccgcacgcg catgttgacg
    19501 atgatcgggc tgccctcgaa gccgtagatc tcgcgcaggc gacgctggat gtagcggcgg
    19561 tactgcgggt cgaggtaccc ggtcgtgaag agcacgaatg tcggcggccg gctcgaggcc
    19621 tgcgtgccga acaggatgcg cggctgcttg ccgccgcgca cggggtgcgg gtgggcggcg
    19681 gtgagctcgg cgaggaacgc gttgaacttg cccgtcgcga tgcgggtgtc ccacgactcc
    19741 agcgccgtct cgagcgccgg cacgagcttc tccatgtggc gtccggtgcg cgccgagatg
    19801 ttgacgcgcg gcgcccacga cacgtgcgcg aggtcggtct cgatctcgcg ctcgaggtag
    19861 cggcggcgct cgtcgtcgag gaggtcccac ttgttgaacg cgagcacgag cgcgcggccc
    19921 gactcgagca ccagctcgat gatgcggatg tcctgctcgc tgatgacctc ggagacgtcg
    19981 atcatgacga ccgcgacctc cgccttctcc agcgccgcgc tcgtgcggag cgacgcgtag
    20041 aagtcggcgc cctgggcgag gtgcatgcgg cggcggatgc cggcggtgtc gacgaagcgc
    20101 cacaccttgc cggcgatctc gacctgctcg tcgaccgggt cgcgcgtggt gccggcgagc
    20161 tcgttgacga ccacgcgctc ctcgcccgct gccttgttga gcaggctcga cttgccgacg
    20221 ttcgggcggc cgaggatggc gacgcggcgg ggtccgccga cctcctcctt ggcgaccttg
    20281 gagacgagcg gcagggtctt cagcacgagg tcgagcagat ccgcgacgcc gcggccgtgc
    20341 agcgcggaga cggggtgcgg ctcgccgagg ccgagcgacc acagcgaggc ggcgttcggc
    20401 tcctggcgcg cgtcgtcgac cttgttggcc gcgaggatca ccgtcttctt ggtcttgcgg
    20461 agcaggcgga cgacgtgctc gtccgtgctc gtggcgccga cgttggcgtc gacgacgaac
    20521 agcacggcgt cggcgaggtc catcgcgatc tcggcctgca tggccacgga ggcgttgatg
    20581 cccttcgcgt cgggctccca gccgccggtg tcgacgagcg tgaaccagcg gcccgcgtgc
    20641 tcggccttgt aggagacgcg gtcgcgcgtg acgccggggg tgtcctcgac gacggcctcg
    20701 cggcggccga ggatgcggtt gatgagcgcc gacttgccga cgttcgggcg gccgacgacc
    20761 gcgagcacgg gcagcgccgg caggtacgtg acctggtcgg ggtcgtccgt ggcggactcg
    20821 aggacctcga ggtcctcgtc gtccagctcg tagtcctcga gcccggcgcg gagcgtctgc
    20881 gcgcgctggg aagcgagctc ctcgtcgatg ctcgacaggc gctcgtggag cccgctgtcg
    20941 agctcgggga agtcgtcgtc gtgatcagcc atgttgtcct ctggcgtgtc ggcccgtcac
    21001 cgggtcgcgc ctcaatctgt tcgtgcgtga acgagatcga ccaccgcctg gacggtctgg
    21061 tcgaagtcga tgtccgtgga gtcgatggtg gtcacaccat ctgcggcgtt catgaaatcg
    21121 acgacctgcg agtcggcccg atcccgggag gcgagtgatt cgccgaccgc ggctgccgac
    21181 tgggtcgacg tctccgcgga acgcctgctc atcctagctt ccggggaggc cgtcagcaga
    21241 atgcgcacct gggcgtcggg cgcgacgacc gtcgtgatgt cgcgaccctc gaccacgatg
    21301 ccgggcttgt cgctcgacgc catgagcgag cggaacagct ccaccatgta gtgccgcacc
    21361 tcgggcacgc gggccacgcg gctcacgacg gcggacacgc ggggctcgcg gatcgcctcg
    21421 gtgacgtcgg tgccgcggac gctcacgcgc gtctcggacg gatcgatcgc gatgtcgtag
    21481 tcgaagccct cgatcaggct cgtgacggtg gcgggatcct ccgtgtcgac gccgctctcc
    21541 agcgcgaacc agctgagcgc gcggtacgcg gcgcccgtgt cctggtagtc gaagccgagg
    21601 gcgcgcgcgg cggcgcggct cacgctcgac ttgccgctgc cggcggggcc gtcgacggcg
    21661 acgaccgtgc ggttgagcgt ggcgtccacc agcagggtgt cctccagggg gtcgggtgcg
    21721 ggcgtcgtgt ctccggtcat ccggcgatcc tccagttccg ttcttcgagc cgcgcgacca
    21781 ggcggtcgcg ggcctcgggc agcacggcga tctccacgag acccacctgc gcgccctgcg
    21841 agtgctcgag gcgcaggtcc tcgatgttga cgtcggcggc gcccacgtcg tcgatcagcg
    21901 cagccagctg gccggggcgg tcgtcgatca tcacggtgac ggcggcgaag cggcggtcct
    21961 ggccgtgctt gccggggatg cgcgcgacgc cggcgttgcc cgcgtggatc cgctcggcca
    22021 cccgcagccg ggccccctgc gcgtcaacgt cgtcgagcgc gtcgatgacg tcgtcgaggt
    22081 cgcggcgcat ggcgcggagg atcggcacga cgcgggaggc gttcgcgccg aggatctgca
    22141 cccacagcgc cgcgtcgctc gacgcgatgc gcgtggtgtc gcggagcccc tggccggaga
    22201 ggccgagcgc cgccgcgtcg ccgtcggcca gtcgcgacgc caggaggctc gcgacgacct
    22261 gcggcacgtg cgagaccagc gccaccgagg cgtcgtgctc ctcggcggtc atctcgatgg
    22321 gcacggcgcc gaggtcgagg atcagctgct cgacgggcgc gcccgcggcg taggtgatgc
    22381 cgtcgtggcc cgcgatgacc cagggccggc cgaggaagag gtcgccggtc gcggagacgg
    22441 ggccgccgcg ctcgcgcccg gcgagcgggt gcgatccgag gtagcgggag aggtcggcgc
    22501 ccatcgcggc gagctccgcg agcggcgcgg ccttcacgct cgcgacgtcc gtgacgagcg
    22561 cgtccgggtg cgcggcgagc tcggcggcga ccacgcgcgc ggtcacgtcc ggcggcacgc
    22621 agaccacgac gagcgacggc cgatcggggg ccgcgccgat gtcggcgatg cgtcccgccc
    22681 ccatgtccgc ggcgaggcgg agcgtggtcg gcgacgcgtc ggcgagcacg acgtcgacgc
    22741 cgcgcgcgcg gaggccgagg gcgatgctcg tgccgaggag tcccgtgccg acgatgcgga
    22801 cggtgccctg cacgcgcgtg tcggtcgcgg cggccgcgcc cgcggcctcg ctcactcgcc
    22861 gtcctcgcgg tccacgtccc cctgcgcctc ggcggccgcg ccggcgccct gcggcgtcgc
    22921 gggtccggcc tgcgcgcggg cctcgcgcga gatggtgagg agctggccga gctcgtcgga
    22981 ggtgaggtcg cgcacgcggc cgacgcccag ggatccgagg tgcagcggcc cgaactggcg
    23041 acgcacgagc tcctccaccg ggtggccgac ctcgtcgagc atgcggcgca cgatgcggtt
    23101 gcggcccgag tgcagcgtga tctccacgag cgtctggtcg ccgccgcccg agaggatgcg
    23161 cg
//
