LOCUS       NC_013656              26442 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Lactococcus lactis subsp. lactis KF147, complete sequence.
ACCESSION   NC_013656
VERSION     NC_013656.1
KEYWORDS    RefSeq.
SOURCE      Lactococcus lactis subsp. lactis KF147
  ORGANISM  Lactococcus lactis subsp. lactis KF147
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B., Wels,M., van Hijum,S.A.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Complete genome sequence of Lactococcus lactis subsp. lactis KF147,
            a plant-associated lactic acid bacterium
  JOURNAL   J Bacteriol 192 (10), 2649-2650 (2010)
   PUBMED   20348266
REFERENCE   2  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Starrenburg,M.J., Boekhorst,J., Renckens,B.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Genome-scale genotype-phenotype matching of two Lactococcus lactis
            isolates from plants identifies mechanisms of adaptation to the
            plant niche
  JOURNAL   Appl Environ Microbiol 74 (2), 424-436 (2008)
   PUBMED   18039825
REFERENCE   3  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Complete genome sequence of Lactococcus lactis ssp lactis KF147
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-DEC-2009) NIZO Food Research, Kluyver Centre for
            Genomics of Industrial Fermentation, PO Box 20, Ede 6710 BA, The
            Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000025045.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 01:08:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,639
            CDSs (total)                      :: 2,548
            Genes (coding)                    :: 2,493
            CDSs (with protein)               :: 2,493
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 25 of 55
            Pseudo Genes (incomplete)         :: 23 of 55
            Pseudo Genes (internal stop)      :: 14 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:59:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2446357
            Orig. end                         :: 2472799
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001834.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria source: Dr. W.J. Kelly, Agresearch Limited, New Zealand;
            william.kelly@agresearch.co.nz.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26442
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="7"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..26442
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26442
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16442](-)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16442)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     gene            complement(45..536)
                     /locus_tag="LLKF_RS12010"
                     /old_locus_tag="LLKF_2393"
     CDS             complement(45..536)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865170.1"
                     /locus_tag="LLKF_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2393"
                     /product="hypothetical protein"
                     /protein_id="WP_012898637.1"
                     /transl_table=11
                     /translation="MTYYLEEEDFENLFSEMKPIVMKLMKQIRIRTWKIEDYLQEGMII
                     LHLLLEEQSDGQKLHTKFKVKYHQRLIDELRRSYAKKRSHDHFIGLDVYECSDWINSGD
                     TSPDNEVVFNHLLAEVYEGLSAHYQDLLLRQMRGEELTRMQRYRLREKIKAILFSEDEE
                     "
     misc_feature    589..598
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(793..2523)
                     /gene="ezrA"
                     /locus_tag="LLKF_RS12015"
                     /old_locus_tag="LLKF_2394"
     CDS             complement(793..2523)
                     /codon_start=1
                     /gene="ezrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132670.1"
                     /locus_tag="LLKF_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2394"
                     /product="septation ring formation regulator EzrA"
                     /protein_id="WP_003132670.1"
                     /transl_table=11
                     /translation="MSSTVIILIVVLLVILVAFYAFAILMRKKTEDRILALEERKESLF
                     DLPVQEEIDSVKKMHLVGQSQTIFREWNQKWLDLSSNSFADLEEHIFEAEQLNDSFHFF
                     RARESVADSEAQIELMEGDVEGIRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNA
                     DLYGTVITELEKHLANIETEFSQFVTLNSTGDPIEAAEVLETAEEHTIALRAITEQIPS
                     FIKTIEKDVPKRLEELQEASDKFVAEEYILPDNVNIKERMDDLHDHLVESSSLLEQFEL
                     DRVEAELGLIQEKVEELYAIFEREYSARRNVEKRSSVLKEYIEHIRANNKNLLLEIDHV
                     TQAYILSGNEKGYVRGYQEHLESLDSDVDEILGNIQAKTMPYSILSRRVNSVVNALEDI
                     EKNQIKISDTLTGLRDEERAAQEIAERFDSELRTIKRYVEKCNLPGLPKDYLDLFFTTG
                     DRVQNLFKELGRVRINIDTINHLVDVSTEDMHVLKEATTNLTDHAVLAEQLIQYANRYK
                     AANEQVAQGISRALQLFENSRDYDGSFDEISKTLELVEPGAASRISGVYFKNKPTPDYL
                     "
     gene            complement(2728..3756)
                     /gene="tsf"
                     /locus_tag="LLKF_RS12020"
                     /old_locus_tag="LLKF_2395"
     CDS             complement(2728..3756)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tsf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906339.1"
                     /locus_tag="LLKF_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2395"
                     /product="translation elongation factor Ts"
                     /protein_id="WP_010906339.1"
                     /transl_table=11
                     /translation="MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGI
                     AKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETDFVAKNDQFVALVKETAELIASKKP
                     ATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIG
                     VVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLV
                     NKPELPHHEFGSKSQLTEEVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTK
                     VDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKA
                     GL"
     misc_feature    complement(3802..3815)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            complement(3879..4646)
                     /gene="rpsB"
                     /locus_tag="LLKF_RS12025"
                     /old_locus_tag="LLKF_2396"
     CDS             complement(3879..4646)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /function="Ribosomal protein S2"
                     /gene="rpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906340.1"
                     /locus_tag="LLKF_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2396"
                     /product="30S ribosomal protein S2"
                     /protein_id="WP_011836067.1"
                     /transl_table=11
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMKPYIFTERNGIHVIDLQK
                     TVKLVDDAYNYVKNASQEGAVVLFVGTKKQAAEAVKEEALRAGQYYVNHRWLGGMLTNW
                     NTIQTRVTRLKEINKMEEEGTFEVLPKKEVVLLNKERERLEKFIGGIADMPRIPDVMYI
                     VDPHAEQIAVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDAIRAVKLITAKMADAII
                     EGRQGEDAAEDFVAEEAASEESLEELAEIVEGK"
     gene            5005..6030
                     /locus_tag="LLKF_RS12030"
                     /old_locus_tag="LLKF_2397"
     CDS             5005..6030
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865172.1"
                     /locus_tag="LLKF_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2397"
                     /product="lactonase family protein"
                     /protein_id="WP_012898638.1"
                     /transl_table=11
                     /translation="MKEKILLGGYTKRVSKGVYSVLLDTKAAELSSLNEVAAIQNPTYI
                     TLDEKGHLYTCAADSNGGGIAAFDFDGETATHLGNVTTTGAPLCYVAVDEARQLVYGAN
                     YHLGEVRVYKIQANGSLRLTDTVKHTGSGPRPEQASSHVHYSDLTPDGRLVTCDLGTDE
                     VTVYDVIGEGKLNIATIYRAEKGMGARHITFHPNGKIAYLVGELNSTIEVLSYNEEKGR
                     FARLQTISTLPEDYHGANGVAAIRISSDGKFLYTSNRGHDSLTTYKVSPLGTKLETIGW
                     TNTEGHIPRDFNFNKTEDYIIVAHQESDNLSLFLRDKKTGTLTLEQKDFYAPEITCVLP
                     L"
     misc_feature    6162..6177
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(6229..6244)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            6262..8973
                     /gene="adhE"
                     /gene_synonym="adhC"
                     /locus_tag="LLKF_RS12035"
                     /old_locus_tag="LLKF_2398"
     CDS             6262..8973
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006066 - alcohol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="adhE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="adhC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132664.1"
                     /locus_tag="LLKF_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2398"
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="WP_012898639.1"
                     /sec_met_domain="Aldedh (E-value: 4.7e-18, bitscore: 62.2,
                     seeds: 89, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 5.4e-107, bitscore:
                     354.9, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKKAAPAAKKVLSAEEKAAKFQEAVAYTDKLVKKAQAAVLKFE
                     GYTQTQVDTIVAAMALAASKHSLELAHEAVNETGRGVVEDKDTKNHFASESVYNAIKND
                     KTVGVISENKVAGSVEIASPLGVLAGIVPTTNPTSTAIFKSLLTAKTRNSIVFAFHPQA
                     QKCSSHAAKIVYDAAIEAGAPEDFIQWIEVPSLDMTTALIQNRGLATILATGGPGMVNA
                     ALKSGNPSLGVGAGNGAVYVDATANIERAVEDLLLSKRFDNGMICATENSAVIDASVYD
                     EFIAKMQEQGAYMVPKKDYKAIESFVFVERAGEGFGVTGPVAGRSGQWIAEQAGVKVPK
                     DKDVLLFELDKKNIGEALSSEKLSPLLSIYKAETREEGIEIVRSLLAYQGAGHNAAIQI
                     GAMDDPFVKEYGEKVEASRILVNQPDSIGGVGDIYTDAMRPSLTLGTGSWGKNSLSHNL
                     STYDLLNVKTVAKRRNRPQWVRLPKEIYYEKNAISYLQELPHVHKAFIVADPGMVKFGF
                     VDKVLEQLAIRPTQVETSIYGSVQPDPTLSEAIAIARQMKQFEPDTVICLGGGSALDAG
                     KIGRLIYEYDARGEADLSDDASLKELFQELAQKFVDIRKRIIKFYHPHKAQMVAIPTTS
                     GTGSEVTPFAVITDDETHVKYPLADYQLTPQVAIVDPEFVMTVPKRTVSWSGIDAMSHA
                     LESYVSVMSSDYTKPISLQAIKLIFENLTESYHYDPAHPTKEGQKARENMHNAATLAGM
                     AFANAFLGINHSLAHKIGGEFGLPHGLAIAIAMPHVIKFNAVTGNVKRTPYPRYETYRA
                     QEDYAEISRFMGFAGKDDSDEKAVQALVAELKKLTDSIDINITLSGNGVDKAHLERELD
                     KLADLVYDDQCTPANPRQPRIDEIKQLLLDQY"
     gene            complement(9311..9808)
                     /locus_tag="LLKF_RS12040"
                     /old_locus_tag="LLKF_2399"
     CDS             complement(9311..9808)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012898640.1"
                     /locus_tag="LLKF_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2399"
                     /product="nitroreductase family protein"
                     /protein_id="WP_012898640.1"
                     /sec_met_domain="PF00881 (E-value: 2.6e-07, bitscore: 28.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLEELIQLRKSNKFHNIGVNVESVIEVVKKSYYNFEKHSVPSA
                     GAIYGLKVLLFYKNNKKIFNSKGEISTEKFEINQIKKTCFYDDKYFSSSSILVAVAYDY
                     DKYFGKYGNCGIRYASIECSAFLQNFQLLLSEKEIYGCPLGFVDNDALLGIEEPLIYFI
                     IN"
     gene            complement(9795..10004)
                     /locus_tag="LLKF_RS12045"
                     /old_locus_tag="LLKF_2400"
     CDS             complement(9795..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011677212.1"
                     /locus_tag="LLKF_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2400"
                     /product="hypothetical protein"
                     /protein_id="WP_003132661.1"
                     /transl_table=11
                     /translation="MKYKLNPLFTLRKTDKAVFNFSRAELTQFNDTGFDILLAVLEQES
                     DREWTDDEDEFLKELIKEKIVEES"
     gene            complement(10001..10828)
                     /locus_tag="LLKF_RS12050"
                     /old_locus_tag="LLKF_2401"
     CDS             complement(10001..10828)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427187.1"
                     /locus_tag="LLKF_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2401"
                     /product="radical SAM protein"
                     /protein_id="WP_012898641.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.2e-10, bitscore: 38.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.1e-16, bitscore: 55.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.8e-08, bitscore: 29.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRDDELFLPIKVYIYLTNHCHYECDYCFLKEMKMLNTKEISKED
                     LEKIAYYLEKYKVPLVAICGGDPILHPKLIDFVQLLSEHKNYPTIATNAVDVSYKYLYQ
                     LKSAGIRYLQIGIDSLRYSKLDNYKENGHLRKVEKTVKYLKELGILYGFATCVTRKNIG
                     ELSKIASYAKETGAELLKLSTYDGENQVYKLTEIQKEELKIFVRQYNTDGIYVRYSPVQ
                     ETLNYVSEYPSLTIYANGDLAIEETGDVIGNISTSEPAVEYKKYILEKWRTNK"
     gene            complement(10821..12944)
                     /locus_tag="LLKF_RS12055"
                     /old_locus_tag="LLKF_2402"
     CDS             complement(10821..12944)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012898642.1"
                     /locus_tag="LLKF_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2402"
                     /product="radical SAM protein"
                     /protein_id="WP_012898642.1"
                     /sec_met_domain="PTHR43273 (E-value: 3.3e-35, bitscore:
                     119.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.3e-08, bitscore: 29.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.9e-20, bitscore: 69.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINYLKNPLFLTWMLTNKCNLRCKFCYLEDYQGKELELDEINQVL
                     DIIQDKEFTHVSLLGGEPTECEYFEYIIIQLEKLRISYSFSTNGQKLFRNEELIRILSK
                     SKYLKEVQISLESPQKLINDAVRGKGTFESAIKSVALLVKENVPTRLAMVVTKENNSTI
                     QQMIDTCATLGCRELRLMPFMPMGTGLLEKERLFMDYEGLVRACSDLKIPDNLIVTTYL
                     KEENTAETLGCGAGTAACVINSDLTLSACPVVSQTQKSIEKLGNDGSSFDYIWGTSSIF
                     NIWRAGKYRKSTSCNLCPLFEECGGVPMTQFFNGQKILFINRILFDDSFITVVEVIFFS
                     VYLKLSFSDFSSIMGLCLLISLLVQIPTGYLSDKFDRKLMLVLGNGAEIVCLITLLFLP
                     SLIKGSLFIPVLIIEIIRTGMLALASGNFEVLIFNMFKREGKTEKDFMEKSASYFSIGA
                     IIAAISGFVSTVLFSYLVILPLILDLSIKIIKLLSAIFMCSEARYKEMTKIKMKVKSLN
                     HKLLFLLFSLALLFCISRGTFSLYQPVMTSLGIPLYYYGLLIMIVNLSIFVLLRVLKKK
                     VSLLKLSTLLLVSFAVLTFQGVLVIEHFIPGNLFRFLIVAIIFSSMQIIRLFSEGLSSY
                     FINTAIKDRDDKTTIFSLYSTMAQLLLSASFFLMGVVQGGVDNYLMTYLYISAIFVLII
                     MALGIFGKGKKYV"
     gene            complement(13019..13876)
                     /locus_tag="LLKF_RS12060"
                     /old_locus_tag="LLKF_2403"
     CDS             complement(13019..13876)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865177.1"
                     /locus_tag="LLKF_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2403"
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_012898643.1"
                     /sec_met_domain="TIGR01716 (E-value: 4.7e-30, bitscore:
                     102.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNLKTGIIIAFIRETKHLKLKEMTGDDFSESQLAKFEKGETEI
                     TVGKLFTVLENSNVYLDEFQNLYNEYEQSDEYNYRHELAVAYAQKNIKVIKEIQNFWEE
                     KCQQKPDNKFYQINKIVVKINLAMAKGSTVFKEDTDFLMNYLESISEWGRYELWIFGNC
                     LRHFDDNALEYYGMQILGKANYYHSIHLNQQIVIRTFLNLIDTWLRRENLIQAFKYINH
                     LKEIGISINFFYEKILFEYHKAHYKVLQKQNGAIEEMKKNAQTLADYGFPLEAKVLFEE
                     IEKL"
     gene            complement(13987..15126)
                     /locus_tag="LLKF_RS12065"
                     /old_locus_tag="LLKF_2404"
     CDS             complement(13987..15126)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836074.1"
                     /locus_tag="LLKF_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2404"
                     /product="MFS transporter"
                     /protein_id="WP_012898644.1"
                     /transl_table=11
                     /translation="MKIIIKYKQLFLFKLFLSLLPYFFISILIMNALGYRYSEIMIISA
                     MTQIIGVILNLPLGIYAEQKNRKKVLLLNNILSIIAFTLFLFEKFYLAILAAVILGISE
                     ALSSGVMQTFSYEQFPDDVTYRKYLEGSSSIQYLAISVMTIITPAILHFNRFLPIIISV
                     AFIVFSTIFLCFIKLEKREEKQEEKITINIRTLRKGLKVSSKLNLFILLGITVTTLIMS
                     VNSWSSILLKYHYFPLKYLGLVLFTFNVCMAIGSRIKWKKLSIVMLLPLISILLFFTKS
                     VFTTIVLFSIFRLINGGYNNFFIGEFNKLIKNNRVVFWSIYDTFLSLFFIFADLSSGLI
                     AQNLTVEFIYLIFGLISLLILLIYLLARKNIYFRKIKNY"
     gene            complement(15123..16442)
                     /gene="kwcM"
                     /locus_tag="LLKF_RS12070"
                     /old_locus_tag="LLKF_2405"
     CDS             complement(15123..16442)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="kwcM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573366.1"
                     /locus_tag="LLKF_RS12070"
                     /note="This protein, a peptide-modifying radical SAM/SPASM
                     domain protein, cyclizes KxxxW-containing RiPP precursor
                     peptides by creating a Lys-to-Trp crosslink; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="LLKF_2405"
                     /product="KxxxW cyclic peptide radical SAM maturase"
                     /protein_id="WP_012898645.1"
                     /sec_met_domain="Fer4_12 (E-value: 7.3e-06, bitscore: 23.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.8e-14, bitscore: 49.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3e-13, bitscore: 47.2,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.6e-09, bitscore: 33.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVLSNELLFRVEKNGGILINKNNFSRLELSESESIFLSLVKEMG
                     KEKAFNEYIKYFNADSLTKILREKIYKKGEIEEKEVSSFSIINKIQSKIKELKKLNQMS
                     FPLELVIYPSMYCNLHCGFCFLANREDENVHLADDWKKILSQAKENGILSFSILGGEPT
                     KYKDIDNLLKIIDSLKVVTTITTNGQEIKKSTIDIICQSDYITPVISLESIDDFKNFEL
                     MGTRAKRGIELIKLFHERKKKVRLNTVYSNQSEEDIMELLKFAIKNEIDRFSIADYSEV
                     TGFTKITKIYNISDLRKLEEKVRRYLLDNKIDNFNFSVEGCFYFTAFPELIEEGKNLSE
                     FENMYFGCRAKHTKMEILSNGDVLPCIAFLGEKHTSNAFHQTLAEIWKNDSNYTEVREF
                     KTENKDCLKCSMLRICEGGCYPKLQRTLNPNFTKDKTCQL"
     gene            complement(16510..16623)
                     /locus_tag="LLKF_RS13310"
                     /old_locus_tag="LLKF_2406"
     CDS             complement(16510..16623)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836076.1"
                     /locus_tag="LLKF_RS13310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2406"
                     /product="KxxxW-cyclized peptide pheromone"
                     /protein_id="WP_011836076.1"
                     /transl_table=11
                     /translation="MQKELKEQSTKPELLAMLKNVLENSSMAKGDGWAASK"
     misc_feature    16852..16865
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     gene            complement(16945..17973)
                     /locus_tag="LLKF_RS12075"
                     /old_locus_tag="LLKF_2407"
     CDS             complement(16945..17973)
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427190.1"
                     /locus_tag="LLKF_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2407"
                     /product="SepM family pheromone-processing serine protease"
                     /protein_id="WP_003132657.1"
                     /transl_table=11
                     /translation="MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLG
                     KMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSHFNSFTSIYSEQEMTGGLNDAQFNR
                     VNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAVNGQ
                     QFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEV
                     VTTPKVTVNAGSIGGPSAGMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGV
                     DKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKKLKTKMKIVPVKTIQDALDYL
                     EK"
     gene            complement(17960..18457)
                     /gene="coaD"
                     /locus_tag="LLKF_RS12080"
                     /old_locus_tag="LLKF_2408"
     CDS             complement(17960..18457)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906348.1"
                     /locus_tag="LLKF_RS12080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2408"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_010906348.1"
                     /sec_met_domain="CTP_transf_like (E-value: 3.6e-19,
                     bitscore: 66.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNP
                     LFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTVNIAKKLGVTALVRSLRNSQDLEYE
                     KNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKLDE
                     KK"
     gene            complement(18505..19044)
                     /gene="rsmD"
                     /locus_tag="LLKF_RS12085"
                     /old_locus_tag="LLKF_2409"
     CDS             complement(18505..19044)
                     /EC_number="2.1.1.171"
                     /GO_function="GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427191.1"
                     /locus_tag="LLKF_RS12085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2409"
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="WP_003132655.1"
                     /transl_table=11
                     /translation="MRVVSGNYGGRPLKTLAGKTTRPTTDKVKGAIFNMIGPYFEGGRV
                     LDLFAGSGSLAIEAISRGMDHAILVEKDRAAQQVILENIKMTKEPEKFQLLKMSAERVL
                     SNLSETFDLVLLDPPYAKEQIVENLELLQEKKRLTENVIVVCETDKEVELPDLIGKLEL
                     TRQKTYGISKISIYEF"
     misc_feature    complement(19044..19057)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.19"
                     /tool="antismash"
     gene            complement(19215..20435)
                     /locus_tag="LLKF_RS12090"
                     /old_locus_tag="LLKF_2410"
     CDS             complement(19215..20435)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427192.1"
                     /locus_tag="LLKF_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2410"
                     /product="MFS transporter"
                     /protein_id="WP_012898647.1"
                     /transl_table=11
                     /translation="MKDFFGLHPTLKIRLIMNFFGTLCFSTVGGSMTIYYNKYMGAGIT
                     GLLLVISSVMVFLVGLYAGHLSDVQGRRPVMIFSTAITGFGGALATFANSSFYFNPWVT
                     FLGFLIINFGFGFFNTASQAMIVDLTTSGNRRVVYSIQYWIINFAIMIGSGLSGWFFRD
                     YLVWLLLAITIEEIVSCLVVIFWIDESFNPDTQQHKQESNIIKAYFTVAKDRIFMYYLF
                     ASVFIAMIFNQIDYYLPVHLSDSFRTARIFGIEVYGQRMLTIFLMVNTLVIVLFMGRVN
                     KLTKNWSRSSGISIGIILQGLGFMIAFLGRDLTWELIAALIATIGEMILVPFSQALRAD
                     LMDGDQVGTYTGAFSVTQPIASVLSGILVSLSSLYGNIGMTIFMFFIIVLGVLPSLRAI
                     RMHESHS"
     misc_feature    20452..20465
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.11"
                     /tool="antismash"
     gene            complement(20519..21745)
                     /gene="lmrP"
                     /locus_tag="LLKF_RS12095"
                     /old_locus_tag="LLKF_2411"
     CDS             complement(20519..21745)
                     /codon_start=1
                     /gene="lmrP"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836081.1"
                     /locus_tag="LLKF_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2411"
                     /product="multidrug efflux MFS transporter LmrP"
                     /protein_id="WP_012898648.1"
                     /transl_table=11
                     /translation="MKEFWNLDKNLQLRLGIVFLGAFSYGTVFSSMTIYYNQHLGSAIT
                     GILLALSAVATFVAGILAGFFADRNGRKPVMVFGTVIQLLGALLAIASNLPGHVNPWST
                     FIAFLLISFGYNLVITAGNAMIIDASNAENRKVVFMLDYWAQNLSVILGAALGAWLFRP
                     AFEALLVILLLTVLVSFFLTTFVMTETFRPIVKAKEEAENIFQAYKTVLQDKTYMIFMG
                     ANIATTFIIMQFDNFLPVHLSNSFKTITFFGFEIYGQRMLTIYLILACVLVVLLMTTLN
                     RLTKDWSHQKGFIWGSLFMAIGMIFSFLTTTFTPIFIAGIVYTLGEIVYTPSVQTLGAD
                     LMNPEKIGSYNGVAAIKMPIASILAGLLVSISPMIKATGVSLVLALTEVLAIILVLIAV
                     NRHQKTKIN"
     gene            21933..22427
                     /locus_tag="LLKF_RS12100"
                     /old_locus_tag="LLKF_2412"
     CDS             21933..22427
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906351.1"
                     /locus_tag="LLKF_RS12100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2412"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_012898649.1"
                     /transl_table=11
                     /translation="MVNLKEYENDVNDYAIEITKYLISRGSQLVDAEDAVQDTLVKILS
                     LDIFIEPDKLRAFMYRTSIRTYINSYNRSKHYQKIIKNLEKELETAAFLVESSPLPKII
                     EQLPPYYKKLLNAYYYENSSTKQLAEYFECSLSKIKIDLYRARKKLKKQLEKAGYDQWL
                     L"
     gene            22451..23557
                     /locus_tag="LLKF_RS12105"
                     /old_locus_tag="LLKF_2413"
     CDS             22451..23557
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836082.1"
                     /locus_tag="LLKF_RS12105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2413"
                     /product="anti-sigma factor"
                     /protein_id="WP_012898650.1"
                     /transl_table=11
                     /translation="MHTLLIFPYLVLAITLFFGLIRLFIFAINKTRHKLQTTESISNLN
                     KDFHNFALKTKIKRWGLTTWIALTVFSAFIVVGWRVNSAIMEKNFFKTFDYSTAIFTAS
                     APNVAYNNQIIDNYGVFSSNLHSDTYKDIDGYPVPWESYNFSFNVSNVGGLNLNTLSPS
                     VNSNAYFTQTTNQKIASFFSTNTNYKSKDYYGILPTHDADKISQLSNHVAEVAVTFDKA
                     YSYNEIQKMIPKNLLINWYWIGYNDSKSLDAAGQTNWFGLMSNSNYAENGNNSQLTGKL
                     DNTTYQDFKKSVTAIAKKNQITINDFSPSKDALKQVKKYPTLKSAKFSGVILTGQTKNF
                     ANFDKNSWVYASNVGLTVELRPDIKPLK"
     gene            complement(23653..24999)
                     /locus_tag="LLKF_RS12110"
                     /old_locus_tag="LLKF_2414"
     CDS             complement(23653..24999)
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /locus_tag="LLKF_RS12110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2414"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_010906353.1"
                     /transl_table=11
                     /translation="MAHIKFDYSKLTPFVAENELDEIQWQIDGAAKLLHEGKGAGSDYI
                     GWLDLPEDYDKEEFARIQKAAKKIQSDSEVLIVIGIGGSYLGARAAIDFLSNSFVNLQT
                     AEERKAPRILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFEEMLV
                     KKYGREEANKRIYATTDKEKGAVKVNADANNWETFVVPDSVGGRFSVLTAVGLLPIAAS
                     GADITALMEGANAARKEYTSTNVHENDAYAYAALRNILYRKGKFSEILINYEPSLQYFS
                     EWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQWIQEGTRTVFETAIRIEKPRKNINI
                     PELDADLDGLGYLQGKDVDFVNKKAADGVLLAHTDGNVPNMIVTLPEQDEFTLGYAIYF
                     FELAIGVSGYLNGINPFNQPGVEAYKKNMFALLGKPGFEELSKELNDRL"
     misc_feature    complement(25191..25204)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(25192..25205)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     gene            25343..25849
                     /locus_tag="LLKF_RS12115"
                     /old_locus_tag="LLKF_2415"
     CDS             25343..25849
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427194.1"
                     /locus_tag="LLKF_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_2415"
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="WP_012898651.1"
                     /transl_table=11
                     /translation="MMKYTFEIDLDRYKNLAQQKQKTHKKFLAGLAKKPPKQLDKIVKE
                     VHEEVFLEIDCTKCANCCKTLGPLWTEADIERVAKHLKMKVSDFEVAYLRTDEDGDKVF
                     QTMPCPFLGSDNLCSIYEVRPKACREFPHTDRKKIYQINNLTIKNTLYCPAAYEFVEKL
                     SYRLK"
     misc_feature    26166..26180
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
ORIGIN
        1 ttatcaaaaa actccctatt tttattaaaa tagggaattc ctcttcactc ttcgtcttct
       61 gaaaataaga tggcctttat tttttcacga aggcgatacc gttgcatgcg agttagttct
      121 tctcctcgca tttgtcgaag tagtaagtct tgataatgtg cgctcaagcc ttcatatact
      181 tctgccagca aatgattgaa gaccacttca ttatctggac tagtatcacc tgaatttatc
      241 cagtctgagc attcataaac atctaaacct ataaaatggt catggcttcg tttctttgca
      301 taacttcgtc ttaattcatc tattaatctt tgatgatact ttaccttaaa ttttgtatgc
      361 agcttttgac catcgctctg ctcttctaat agaagatgta aaataatcat cccctcttga
      421 agataatcct ctattttcca tgttctaatg cgaatttgtt tcattaattt cataactata
      481 ggtttcattt ctgaaaacag attttcaaaa tcctcttctt ccaagtaata tgtcattgga
      541 aagttctcct tttatattat ctttatttga ttaattagta agatgataga aggcggcgag
      601 tgtatatcta ataaacagtc agggagcatc ttattataat gagctatttt catatctatc
      661 cttccaagac atttttatgg cttttattac attataataa tttttgcgtg ttttacctaa
      721 cgatattatg cgaatattca gaatttataa cccaataaat aaaagcaagg ctatttacct
      781 tgctttttta ttttataagt aatcaggagt aggtttattt ttaaaataaa ctcctgaaat
      841 tctagaagct gcacctggtt ctacaagttc tagcgttttt gaaatttcat caaatgaacc
      901 atcatagtca cggctgtttt caaataattg aagcgctctt gagatccctt gtgctacttg
      961 ttcatttgca gctttatacc gattagcata ttgaatcaat tgttcagcta ataccgcatg
     1021 gtcagtcaaa ttagtcgttg cttcttttaa aacgtgcata tcttcagtgc ttacgtcaac
     1081 aagatgatta attgtatcaa tgttgattct aactcgtcct aattctttga acagattttg
     1141 tactcgatct cctgttgtga agaacaagtc gagataatct ttaggaagtc cagggagatt
     1201 acatttttca acataacgtt ttattgtacg aagttcagaa tcaaagcgtt ctgcaatttc
     1261 ttgagctgct ctttcttcat ctctgagtcc tgtaagggta tcactaatct taatttgatt
     1321 cttctcaata tcttcaagcg cattgactac tgaatttact ctacgtgaaa gaattgagta
     1381 aggcattgtt ttagcttgaa tatttcctag aatttcatca acatctgagt caagagattc
     1441 taaatgttct tgataacctc taacatatcc tttttcgttc ccagaaagga tataggcttg
     1501 tgtaacatgg tcaatttcaa ggagaagatt tttattattt gctctgatat gttcaatata
     1561 ttctttgaga actgatgaac gtttttcaac atttcgacgt gcgctatatt ctctttcaaa
     1621 aatagcataa agttcttcaa ctttttcttg aattaaacca agttcagctt ctactcgatc
     1681 tagttcaaat tgttctaata atgaactact ttcaacgaga tgatcatgta aatcatccat
     1741 tctttcttta atgttgacat tatcgggaag aatgtattct tctgcaacga atttatcact
     1801 cgcttcttgc aattcttcaa gtcgtttagg aacatctttt tcaattgttt taataaatga
     1861 tggaatttgc tctgtaattg cacgtaaagc aatcgtatgt tcttcagcag tctccaaaac
     1921 ttcagccgct tcaatcggat cacctgttga gtttagcgtt acaaactgag aaaattctgt
     1981 ttcgatattg gctaaatgtt tttcaagttc agtaataact gttccataca aatctgcatt
     2041 gtcagcaata tcgctacgta agttatcata taaatcaagg gactcttgaa ttttatttga
     2101 attacgcttt tcttgttcaa caagttgagc aacaccttga cgaattcctt cgacatcacc
     2161 ttccattaat tcaatttggg cctcactatc cgctacagat tcacgagcac ggaaaaaatg
     2221 gaatgaatcg tttaattgtt cagcttcaaa aatatgttct tccaaatcag caaaagaatt
     2281 tgatgataag tcaagccatt tttggttcca ttcacggaaa atcgtttgcg attgtccgac
     2341 gagatgcatt tttttaacag aatcaatttc ttcttgaaca ggcaaatcga aaagcgattc
     2401 ctttcgctct tctaaggcta gtatacggtc ttctgttttc tttcgcatta atattgcaaa
     2461 agcataaaag gctacgagaa taactaataa gacaacaatg aggataatga cagtacttga
     2521 catgctttac tccataaaat gatttaatta cttaaaaata gtttaattac ttaggttaga
     2581 tagattttaa atagatagaa aatctcaaat ataattatag cataatgcgt caaagaaata
     2641 cactattttc ttagttttct aaccgaaaag ccctttttta ttttcaaaat aaaaaaagca
     2701 acctctagag gctgcttttt aattaaatta aagtcctgct tttgctgctt caacttctgc
     2761 tgcgaagtct gtttcagctt tttcaattcc ttcaccaact tcaaaacgtg tgaatgcaat
     2821 tgctttagct ccttttgatt caaggaaagc ttcgacagtt ttgctgtcat ccatgatgta
     2881 aagttgtgca agaagagcaa attgttggtc aacttttgta ttgtcaacga tgaatttagc
     2941 cattttacct ggaagaattt tgtcccagat tttttctggt tttccttcag ctttgagttc
     3001 ttcttcaaat gaagctttcg ctgctgcaag aacttcttct gttaattggc tcttagaacc
     3061 aaattcatgg tgtggaagtt ctggtttgtt aacaagtaca cggctagcgt tgtcttcatc
     3121 aattttgtgg ttcatttgtg ctaattcagc ttttacaaat tctgaatcaa gttcatcagc
     3181 tgaaagaaca gtagggttca ttgcagcgat atgcattgat acttgtttag caagtgtttc
     3241 atctgcacct tcaacgacag aaacaacccc aattttacca ccgttatgtt ggtaagctcc
     3301 aaagtgttga gcatcagttt tttcaattac tgcaaaacga cggaaagtaa ttttttctcc
     3361 gattgtagca gtcgcttgaa caagttctgc ttcaagagta atacctgaag ctgtttcaag
     3421 tgccaatgct tcttcgttag ttgctggttt tttagacgca ataagttctg ctgtttcttt
     3481 aaccaaggca acaaattgat catttttagc tacgaagtct gtttctgagt tcaattcaac
     3541 aatcgctgca acatttccgt ttacagcaat tcctgtaagt ccttcagcgg ctacacgatc
     3601 agctttttta gctgctttcg caatcccttt ttcacgaaga agttctgctg ccgcttccat
     3661 atttccgtca gtttcaacaa gagcgcgttt agcgtccatg attcctgcac cagttttttc
     3721 acgtaattct tttacttgag ctgctgttac tgccattttg taaatctcct atgtgttttt
     3781 ttctgtcagt attgacagta gttttatttt aaaaaaacag gcgaggcgta aggcctcgcc
     3841 tgttgtagtt acttaattag tataagttga agttaaaatt atttaccttc aacgatttca
     3901 gcaagttctt caagtgattc ttctgaagct gcttcttctg ctacgaaatc ttccgctgca
     3961 tcttcacctt gacgtccttc gataatagcg tctgccattt tagctgtaat caatttaaca
     4021 gcacggatag catcatcatt tgcaggaata actacgtcga ttggttctgg atctgcgttt
     4081 gtgtcaacca ttgctacaac tgggattccc aaagttttag cttctttaac tgcgatttgt
     4141 tcagcatgtg ggtcaacgat gtacataaca tctggaatac gaggcatatc agcgatacca
     4201 ccgatgaatt tttcaaggcg ttcgcgttct ttgttaagaa gaactacttc tttcttaggt
     4261 aaaacttcga aagttccttc ttcttccatt ttgttgattt ctttaaggcg tgtcacacgt
     4321 gtttggatag tgttccagtt agtgagcata ccacccaacc aacggtggtt tacgtagtat
     4381 tgaccagcgc ggagagcttc ttctttaact gcttctgcag cttgtttttt agtaccaaca
     4441 aaaaggacta ctgcaccttc ttgtgaagcg ttttttacat agttgtaagc atcgtcaaca
     4501 agttttacag ttttttgaag gtcgataacg tggataccat tacgttctgt gaagatgtat
     4561 ggtttcattt ttgggttcca acgacgagtt tggtgaccga agtgaacacc agcttcaaga
     4621 agttgtttca ttgaaataac tgacatgtta atgtctcctt ttaaaatagt ttttcctctt
     4681 tcatctgtca tccgcagccg caatacttgc gtacactacg actttgtcga gacgaaatgc
     4741 gagatggttg catagcaact ctatcattat acattgtttg acctattttt gcaagtatct
     4801 attcatgctt ctattgttca ataaatctat ttttctagcc actcctattg tctgacaaat
     4861 ttaattgtta atttaggctc tataatcact aaaagagtaa gtttttaaat ttttttctaa
     4921 gaaaaaaatt aatatttttg ctgaaaccgc tttttttgtg ataaaataat tatagtaaat
     4981 aaattagttt gtgaggagag aaatatgaaa gaaaaaatcc ttttaggcgg ctatacaaaa
     5041 cgtgtatcta aaggcgtata tagtgttctt ttggacacta aagctgctga attatcatca
     5101 ttaaatgaag tcgctgcgat tcaaaaccct acttatatca ctctcgatga aaagggacac
     5161 ctctatactt gtgcagcaga tagtaatggt ggaggaatcg ccgcctttga ttttgatggc
     5221 gaaactgcta ctcatctcgg aaatgtcaca accacgggag ctccactctg ctatgttgcc
     5281 gtggacgaag cgcgacaatt agtttacgga gcgaactatc atcttggaga agttcgtgtt
     5341 tataagattc aagctaatgg ctcactccga ttaacggata cagtaaaaca taccggttct
     5401 ggaccacgtc ctgaacaagc tagctcacac gttcattatt cggatttgac tcctgacgga
     5461 cgacttgtca cctgtgattt gggaacagat gaagtcactg tttatgatgt cattggtgaa
     5521 ggtaaactca atattgctac aatttatcgg gcagaaaaag gaatgggtgc tcgtcatatt
     5581 actttccatc caaatggtaa aatcgcttat ttggttggag agttaaattc aacaattgaa
     5641 gttttaagtt acaatgaaga aaaaggacgc tttgctcgtc ttcaaacaat tagcacccta
     5701 cctgaagatt atcatggagc aaatggtgtt gctgccatcc gtatttcatc tgacggtaaa
     5761 ttcctctata cttctaatcg tggacatgat tctttgacaa cttacaaagt aagtcctctt
     5821 ggtacaaaac ttgaaactat tggctggaca aatactgaag gtcatatccc tcgtgatttt
     5881 aatttcaaca aaactgaaga ttatatcatt gtcgctcatc aagaatctga taatttatct
     5941 cttttcttgc gagataaaaa aaccggtact ttaactttgg aacaaaaaga tttttacgct
     6001 cctgaaatca cttgtgtttt accactataa aaatttattt tttcacaaag tttgactgat
     6061 aaactaaaaa agattgctaa ttcctatcaa agaattagca atcttttttt cttcagtaaa
     6121 gcttgttata aaccgttttc taaacttttg atgagtattt ttgtaaaaat tatcacaata
     6181 ttgcttgaca tctataaaaa actttgttaa actattcacg taaaagaaag tgaatgaaat
     6241 cacaaaggag aacctacaaa tatggcaact aaaaaagccg ctccagctgc aaagaaagtt
     6301 ttaagcgctg aagaaaaagc cgcaaaattc caagaagctg ttgcttatac tgacaaatta
     6361 gtcaaaaaag cacaagctgc tgttcttaaa tttgaaggat atacacaaac tcaagtcgat
     6421 actattgtcg ctgcaatggc tcttgcagca agcaaacatt ctctagaact cgctcatgaa
     6481 gccgttaacg aaactggtcg tggtgttgtc gaagacaaag ataccaaaaa ccactttgct
     6541 tctgaatctg tttataacgc aattaaaaat gacaaaactg ttggtgtcat ttctgaaaac
     6601 aaggttgctg gatctgttga aatcgcaagc cctctcggtg tacttgctgg tatcgttcca
     6661 acaactaatc caacatcaac agcaatcttt aaatctttat tgactgcaaa aacacgtaat
     6721 tctattgttt tcgctttcca ccctcaagct caaaaatgtt caagccatgc agcaaaaatt
     6781 gtttacgatg ctgcaattga agctggtgca ccggaagact ttattcaatg gattgaagta
     6841 ccaagccttg acatgactac cgccttgatt caaaaccgtg gacttgcaac aatccttgca
     6901 actggtggcc caggaatggt aaacgccgca ctcaaatctg gtaacccttc actcggtgtt
     6961 ggagctggta atggtgctgt ttatgttgat gcaactgcaa atattgaacg tgccgttgaa
     7021 gaccttttgc tttcaaaacg ttttgataat gggatgattt gtgccactga aaattcagct
     7081 gttattgatg cttcagttta tgatgaattt attgctaaaa tgcaagaaca aggcgcttat
     7141 atggttccta aaaaagacta caaagctatt gaaagtttcg tttttgttga acgtgctggt
     7201 gaaggctttg gagtaactgg tcctgttgcc ggtcgttctg gtcaatggat tgctgaacaa
     7261 gctggtgtca aagttcctaa agataaagat gtccttcttt ttgaacttga taagaaaaat
     7321 attggtgaag cactttcttc tgaaaaactt tctcctttgc tttcaatcta caaagctgaa
     7381 acacgtgaag aaggaattga gattgtacgt agcttacttg cttatcaagg tgctggacat
     7441 aatgctgcaa ttcaaatcgg tgcaatggat gatccattcg ttaaagaata tggcgaaaaa
     7501 gttgaagctt ctcgtatcct cgttaaccaa ccagattcta ttggtggggt cggagatatc
     7561 tatactgatg caatgcgtcc atcacttaca cttggaactg gttcatgggg gaaaaattca
     7621 ctttcacaca atttgagtac atacgatcta ttgaatgtta aaacagtggc taaacgtcgt
     7681 aatcgcccac aatgggttcg tttgccaaaa gaaatttact acgaaaaaaa tgcaatttct
     7741 tacttacaag aattgccaca cgtccacaaa gctttcattg ttgctgaccc tggtatggtt
     7801 aaatttggtt tcgttgataa agttttggaa caacttgcta tccgcccaac tcaagttgaa
     7861 acaagcattt atggctctgt tcaacctgac ccaactttga gcgaagctat tgcaatcgcg
     7921 cgtcaaatga aacaatttga acctgacact gtcatctgtc ttggtggtgg ttctgctctt
     7981 gatgctggta agattggtcg tttgatttat gaatatgatg ctcgtggtga agctgacctt
     8041 tctgatgatg caagtttgaa agaacttttc caagaattag ctcaaaaatt tgtcgatatt
     8101 cgtaaacgta ttattaaatt ctaccatcca cataaagcac aaatggttgc aattcctact
     8161 acttctggta ctggttctga agtgactcca tttgcagtta tcactgatga tgaaactcat
     8221 gttaagtacc cacttgctga ctaccaatta acaccacaag ttgccattgt tgaccctgag
     8281 tttgttatga ctgtaccaaa acgtactgtt tcttggtctg gtattgatgc gatgtcacac
     8341 gcgcttgaat cttatgtttc tgttatgtct tctgactata caaaaccaat ttcacttcaa
     8401 gcgatcaaac tcatctttga aaacttgact gagtcttatc attatgaccc agcgcatcca
     8461 actaaagaag gacaaaaagc ccgcgaaaac atgcacaatg ctgcaacact cgctggtatg
     8521 gccttcgcta atgctttcct tggaattaac cactcacttg ctcataaaat tggtggtgaa
     8581 tttggacttc ctcatggtct tgccatcgcc attgctatgc cacatgtcat taaatttaac
     8641 gctgtaacag gaaacgttaa acgtacccct tacccacgtt atgaaacata tcgtgctcaa
     8701 gaggactacg ctgaaatttc acgcttcatg ggatttgctg gtaaagatga ttcagatgaa
     8761 aaagctgtgc aagctctggt tgctgaactt aagaaactga ctgatagcat tgatattaat
     8821 atcacccttt caggaaatgg tgtcgataaa gctcaccttg aacgtgaact tgataaattg
     8881 gctgaccttg tttatgatga tcaatgtact cctgctaatc ctcgtcaacc aagaattgat
     8941 gagattaaac aactcttgtt agaccaatac taataatctg ttgataaaaa taataaaaac
     9001 gctctgatga attcgtcaga gcatttttta ttatagctta tacaactatc aaaaggtata
     9061 aatcaatttc gatataggct cttttcactc cattgattta tatttctata aaaatcaata
     9121 attaattagc gatagaagtc gagttcatgc atgctaataa tgaaattgtt ttaaattctg
     9181 gtttttcttt atgttctttg cgaacatctt tcacagtttc tttgttcatg aaaattcctc
     9241 cttattatgg tactatattg agcccaaata gttatataag aatcctaaac ttcggatatc
     9301 ttatcaaaga ttaattaata ataaaataaa ttaggggttc ttctattccc aacagagcat
     9361 cattatctac gaatcctaat ggacaaccgt atatctcttt ttctgaaagt agtagctgaa
     9421 aattttgcag aaaagcacta cattcgattg aagcatacct tatcccacaa ttaccatatt
     9481 taccaaaata tttatcgtaa tcatatgcca cagcaacaag aattgaactt gaagaaaaat
     9541 atttatcatc ataaaaacaa gtttttttaa tttgatttat ctcgaatttc tctgtactta
     9601 tctccccttt agagttaaat atttttttat tgttcttata aaaaagtaaa actttcaaac
     9661 catatatagc tccggcagaa ggaacgctat gtttctcaaa attatagtag gattttttta
     9721 ctacttctat tacactttca acatttacac caatattatg aaatttattt gattttctta
     9781 gttgaataag ctcttcaaga ttcttcaacg attttctcct tgattaactc tttcagaaat
     9841 tcatcttcat catctgtcca ctctctatca ctttcttgtt caagaactgc caataaaata
     9901 tcaaaacctg tatcgttgaa ttgtgttaat tccgcccttg agaaattgaa gactgcttta
     9961 tctgtttttc tgagcgtaaa taatgggttt aatttatact tcatttattt gttctccatt
    10021 tttctaatat atatttttta tattctacag ctggttcaga agtggaaata tttccaataa
    10081 catctcctgt ttcttcaatt gctaaatccc cgtttgcata tattgtcagg gagggatatt
    10141 ccgatacata atttaatgtt tcttgaacag gcgagtagcg tacataaatc ccatcagtat
    10201 tatattgtct tacaaagatt tttaactctt ctttttgaat ttctgttaat ttatatactt
    10261 gattttctcc atcataagtt gaaagtttca acagttcggc tcctgtttct ttagcataac
    10321 tcgcaatttt actaagctct ccaatatttt ttcgagtgac acaagttgca aaaccataca
    10381 atatccccaa ttcttttaaa tatttcacag ttttttcaac ttttctaaga tgcccgtttt
    10441 ctttgtaatt atccaatttt gaatatcgca aactatcaat gcctatctgt aaatatcgaa
    10501 ttcctgctga ttttaactga tataaatact tataggatac gtcaactgca ttagtcgcta
    10561 tagttggata attcttatgt tctgatagta attggacaaa atcaataagt tttgggtgga
    10621 gaattggatc tcccccacaa atagcaacta atggtacttt atatttttct aaataataag
    10681 ctattttttc taaatcttct tttgagatct cctttgtatt taacatcttc atttctttaa
    10741 gaaagcagta atcacattcg taatgacaat gattagttaa atatatatac accttaattg
    10801 gtaaaaaaag ttcgtcatct ctaaacatat tttttcccct ttccaaagat acctaaagcc
    10861 ataataatta ggacaaaaat tgcactaata tataaatagg tcatcaaata gttatcaact
    10921 cccccttgaa caacacccat caggaagaaa gaagcagata gtaaaagctg ggccattgta
    10981 gaataaagag aaaaaatagt tgttttatcg tctctatcct taatcgcggt gttgataaaa
    11041 taagaggaga gcccttctga aaatagtctg ataatctgca tacttgaaaa tattatcgct
    11101 acaatcaaaa aacgaaaaag atttcctggt ataaaatgtt caattaccaa aactccttga
    11161 aaagtaagaa ccgcaaaaga aacaaggagt aatgttgaaa gttttaacag cgatactttc
    11221 tttttcaaaa ctctcaaaag aacgaatatc gacaggttca ctatcataat aagtaggcca
    11281 taataataaa gaggaatacc taatgaagtc ataactggtt ggtataaaga aaatgtcccc
    11341 cttgaaatac aaaacaaaag ggcaagcgag aacaagagaa ataacaattt atgatttaag
    11401 gactttactt tcatttttat ttttgtcatt tctttatatc tcgcttcaga acacatgaaa
    11461 atagcagata ataatttgat gatttttatc gataaatcca atataagtgg caaaatcact
    11521 agataggaaa atagaaccgt ggaaacaaat ccagaaattg ctgctataat cgctcctatg
    11581 gaaaaatatg aggcggattt ctccataaaa tctttttcag tttttccttc tctcttaaac
    11641 atattaaata ttaacacttc aaaattacca ctcgctaaag ccaacatgcc tgttcttata
    11701 atttctataa ttaaaactgg aataaataaa gagcctttta tcaaactagg aagaaaaagt
    11761 aaagttataa gacacacaat ttccgcacca tttcctaata ctaacattaa tttcctatcg
    11821 aacttatcgg ataagtaacc tgttggaatc tgaactaaca acgaaattaa caaacataag
    11881 cccataatac ttgaaaaatc tgaaaaagaa agctttaaat acacactgaa aaatataacc
    11941 tctacaaccg ttataaatga atcatcaaaa agtattctat ttatgaataa aattttctga
    12001 ccattgaaaa attgagtcat tggtaccccc ccacattcct caaatagcgg acataagtta
    12061 cacgaggttg attttcgata ttttcccgct ctccatatat taaaaatcga acttgttccc
    12121 catatgtaat caaaacttga accatcgtta cctaattttt cgatagattt ttgggtttga
    12181 gatactacag gacaggctga aagtgtcaag tcactattta taacgcaggc agctgttcca
    12241 gcaccacaac ctaaagtttc agcggtattc tcttctttta ggtaagttgt gacaattaga
    12301 ttatctggta tttttaaatc tgagcatgct cgaactaaac cttcataatc catgaatagg
    12361 cgttcttttt ctaataatcc cgttcccatg ggcataaatg gcattaatcg caattctcta
    12421 caccctaatg tggcacacgt atcaatcatt tgttgaatgg tagaattatt ttcttttgtc
    12481 acgaccatag caagccgtgt aggaacattc tcttttacta atagtgctac actttttatt
    12541 gcactttcaa atgttccttt ccctctgact gcgtcattga ttaacttttg gggagactct
    12601 aaagaaattt gaacctcttt taaatatttg gatttagaaa gtattctaat taactcttca
    12661 tttctaaata gtttttgacc attagttgaa aatgagtatg aaattctcaa tttttctagt
    12721 tgaataataa tatattcaaa gtactcacat tctgtcggtt caccgcccaa tagagaaaca
    12781 tgggtaaatt ctttatcttg tataatatct aggacctgat ttatttcatc aagctccaac
    12841 tcttttcctt gataatcttc caaataacaa aatttacacc ttaaattaca tttgttggta
    12901 agcatccaag tcaggaacag tggatttttt aggtaattaa tcatcttact tctccaatct
    12961 ataaaaaaat acagataaaa ttgggtggaa attttctttt ggaatatatg ccaaagccct
    13021 ataatttttc aatttcttca aaaaggacct ttgcttctag tgggaaacca taatctgcaa
    13081 gagtttgcgc gttttttttc atttcttcta tcgctccgtt ttgtttttgc aataccttat
    13141 aatgagcttt gtgatattca aagagaattt tttcatagaa aaaattgata cttattccta
    13201 tttcttttaa atggttgata tatttaaaag cttgtattaa gttttctcga cgtaaccaag
    13261 tatcaatgag atttaaaaat gttcttatta cgatctgctg attgagatga attgagtgat
    13321 aataatttgc ttttcctaaa atttgcattc cataatactc taaagcatta tcatcaaaat
    13381 gtcgaagaca attcccaaaa atccatagtt catagcgtcc ccattcgctg atagattcaa
    13441 ggtagttcat caaaaagtca gtatcttcct taaaaacagt agaacctttt gccattgcta
    13501 agttgatttt aaccactatt ttattaatct gataaaattt attatcaggt ttctgttggc
    13561 atttttcttc ccaaaaattt tgaatttcct ttattacttt gatatttttt tgcgcataag
    13621 ccacagccaa ctcgtgacgg tagttgtatt catctgattg ttcatattcg ttataaaggt
    13681 tttgaaattc atctaaatag acatttgagt tttctaaaac ggtaaatagt ttacccaccg
    13741 taatctctgt ttctcctttt tcaaattttg cgagctgaga ttctgaaaaa tcgtcaccag
    13801 tcatttcttt taatttcaga tgcttcgttt ctctgataaa agcaattatt attccggttt
    13861 ttaaattttt ttccatttca ttttcccttt gtcatatatt ccaaatttat taaattattt
    13921 gaaattatta tacaactttg cttttagctt gtaaactaga taaaaaaact actgacagct
    13981 tttctgtcag tagtttttta tttttctaaa ataaatattt tttctagcta aaagataaat
    14041 taggagaata agtaaggaaa tcagaccaaa tattaaataa ataaattcta cagttaaatt
    14101 ttgggcaatt agaccgcttg ataaatcagc aaaaataaaa aacagagata aaaatgtatc
    14161 atatattgac cagaaaacta ctcgattatt ttttattagt ttattaaatt ccccaatgaa
    14221 aaagttatta tagccaccat ttattaatct aaaaatagaa aataaaacaa tagtagtaaa
    14281 taccgatttt gtaaaaaata aaagaattga tattaatggt aatagcataa ctatcgataa
    14341 ttttttccac tttattcgac tcccaattgc catacataca ttaaaagtaa acaaaacaag
    14401 ccctaaatac ttaagtggaa aataatgata tttcaataaa atactactcc aactattgac
    14461 agacatgatg agtgttgtga cagttattcc taataaaatg aataagttta gcttagacga
    14521 tacttttaat ccctttcgta atgtccttat attaatagtt attttttctt cttgtttttc
    14581 ttctcttttt tctaatttta taaaacataa aaaaatggtt gaaaaaacaa taaatgctac
    14641 tgatattatg attggtaaaa aacgattgaa atgtagtatg gctggtgtga taattgtcat
    14701 cactgatatt gcaagatatt gtattgaact gctgccttca agatatttgc gatatgtaac
    14761 atcatctgga aattgttcat aagaaaaagt ttgcattact ccagaagata gagcttctga
    14821 tatcccaagt atgaccgctg ctaagattgc taaataaaat ttttcaaata aaaatagggt
    14881 aaaagcaata attgacaaaa tattattaag taataatact ttttttctat ttttttgttc
    14941 agcataaata cctagcggta gatttaaaat cactcctatt atttgcgtca ttgcactaat
    15001 aatcataatc tcagaatatc tataacccaa agcattcata attaatatgc taataaaaaa
    15061 atagggaagg agggacaaaa agagtttaaa tagaaaaagt tgtttatatt tgattatgat
    15121 tttcatagct gacaagtttt atctttcgta aagttaggat ttaatgttct ttgtaatttg
    15181 ggatagcatc ccccctcgca aattcttaac attgagcact ttaaacaatc tttattttct
    15241 gttttaaatt ctctaacttc tgtataattt gaatcgtttt tccatatttc agccaatgtt
    15301 tgatgaaaag cattggaagt atgcttttca cctaaaaatg caatacaagg taagacatcc
    15361 ccgttagata aaatctccat tttcgtatgc ttcgctctac aaccaaaata catattttca
    15421 aattccgata gattttttcc ctcctcaatt aactctggaa aagccgtaaa ataaaaacat
    15481 ccttcaactg aaaaattgaa attatctatt ttattatcta gtagatatct tctaactttt
    15541 tcttctaatt ttctcaggtc tgatatattg tatatttttg ttatttttgt aaaaccagtc
    15601 acttcggagt agtccgcaat agaaaaacgg tcaatttcgt ttttaatcgc aaacttcaag
    15661 agctccataa tatcctcttc actttgatta gaataaaccg tatttaatct gactttcttt
    15721 tttctttcat gaaaaagctt tattaattct attcctcttt ttgcccttgt acccatgagt
    15781 tcaaaatttt taaaatcatc tattgattca agagatataa ctggggtaat ataatcagat
    15841 tggcaaataa tatctattgt tgattttttt atctcttgac catttgttgt tattgttgtc
    15901 actactttca atgaatcaat aatttttaaa agattatcta tgtctttata tttcgttggc
    15961 tccccaccta atatagaaaa tgataaaatt ccattttctt ttgcttgact taaaatcttt
    16021 ttccaatcat ctgcaagatg aacattttcg tcttctctgt ttgcaagaaa gcaaaagcca
    16081 caatgaagat tgcaatacat actaggataa atcactaact ctagcggaaa actcatttga
    16141 tttaattttt tcagctcttt aatcttactt tgtattttat taataattga gaaagaagat
    16201 acctcttttt cttctatctc tcctttttta taaatttttt ctcgtaaaat ttttgttaga
    16261 gaatcagcat taaaatattt tatgtattcg ttaaatgctt tttcttttcc catttctttt
    16321 actaaagata aaaaaataga ctcactttct gacaattcta atctgctaaa attattttta
    16381 tttattaaaa ttccgccgtt tttctcaact ctaaataata attcatttga taaaacgtac
    16441 atattaacat cctttctaaa tattactcaa aaaaaggcga ctaaacgtcg ccaattctgc
    16501 tatcaaattt tatttgctag cagcccatcc atctccctta gccattgaac tattttccaa
    16561 tacattttta agcattgcca aaagctctgg tttggttgat tgttctttaa gttctttttg
    16621 cataataaat ctccttttaa tatagacaga taccaatttt gattcaattg gtatctgtta
    16681 ttttatcaaa attattgata gtataaattt tatttggaat atatgccaaa actctattaa
    16741 ttgttaagtt catgagaaaa cccacgttgt tactatattg gctctctttt tttcttcttt
    16801 atttttatta ctctatctcc agtttttact ttcaaaaccc caattctaaa ctttttataa
    16861 aaaaatttat tttatttatc ttttgtcata tattccaaaa atatccaatg aaaaaactac
    16921 tgacagaaaa gctgtcagta gtttttattt ttctaaataa tctaaagcgt cctgaatagt
    16981 tttgacggga acgattttca tcttcgtttt tagtttttta gcggcggctt tggctccaag
    17041 gtaattgttg ctactttctt ttttggtgcc tgagtcaggc actaagaaga cttttgcccc
    17101 ttctttgctc gctgtggcta cttttttatc aacaccgccg atttggccaa tgcttccgtc
    17161 atgttcaatc gtcccagttc cagcaatttc gcgaccgttt cgcaaatctt ttcctgtcaa
    17221 ctgactgtaa atttctagtg taaacatcat ccccgcagag ggaccaccga ttgaacccgc
    17281 gttgacagta acttttggag tcgtcacgac ttcagtatgg tcaactaggc tgatcccaat
    17341 tcctgttttt ccattagcaa ttttgatgta tttgccagtt gacttgtgct ttgtgccgtc
    17401 aattctcgtg tattcaatcg ttactgaatc accgactttt tgtttggaaa cataagcaat
    17461 catgtcggca cttgatgtaa actgttgacc attgactgct gtaatcgtat ctgcaagttc
    17521 tagcttattt ttaaaggtcg aatttttggc aatatcaagg acataaacgc cttcatattt
    17581 aagttcataa ggtttattag ctaatttaaa agcttgataa atcgctgtat tctgtgccgt
    17641 ttccatgtaa aactggttga cacggttgaa ctgtgcgtcg ttaagtccac cagtcatttc
    17701 ttgctcactg taaatgcttg taaaactatt aaaatggctg taaatcattg tagcaagatt
    17761 tgctcgtgca atttggacag tcgtcagaaa aaaatcacct ttatgttcat cttttttgcc
    17821 ttcaactttg accattttcc ctaaaggctc ggttgttccg ggcatttcca catagtaact
    17881 cgttggataa aataaagcta aaagggcaac aacaattaga ccaatcgaga ttccccattt
    17941 taatttggga ttaatttttt tatttttttt catctaattt ccttaattca cgactcacat
    18001 tttctggaac ccaagcactg acatcttgac caaaggcatg taattctcgc atccgtgttg
    18061 aatttaatgg ttcaagttct ggttttgcta agaaaaagat ggtttcaatg cctgtcattt
    18121 ccatattaaa atagaacata tttttttcat attctaaatc ttggctatta cgcaaagaac
    18181 gaaccagagc tgtcacgcca agttttttag caatattcac tgtcaaatca cgttcatgtt
    18241 tgatgacttt gactttatga gttactgaca gacttgtcag tgcttcttct agcatttcca
    18301 ctcgtttatc agttggaaaa agtggatttt tttggtcatt tttaaaaatt ccaacataaa
    18361 gttgatcaaa atgttgactg gcacgtttga taacgtctaa atgaccattt gtcagtgggt
    18421 caaaagttcc tgtaaagagt ccaatttttt ctgtcattac ttttttcttt cttaatttac
    18481 tgacagaatt tctgtcagta aaagtcaaaa ttcataaatt gaaattttag aaattccgta
    18541 agttttttgt ctggtcagct ctaatttccc aattaggtca gggagttcaa cttccttgtc
    18601 tgtttcacag acgacaatta cattttctgt cagtcgtttt ttctcttgca aaagttctaa
    18661 gttttcaaca atttgttctt tagcataagg tgggtctaag aggactaaat caaaagtctc
    18721 tgacaagttt gataagactc gttctgctga catttttaat aattgaaatt tttcaggctc
    18781 tttggtcatc ttgatatttt ccaaaatgac ttgttgagct gctctgtctt tttcgacgag
    18841 aatggcgtga tccattcctc ttgaaatggc ttcaattgcc aaactgcctg agcctgcaaa
    18901 taaatcaaga acacgtcccc cttcaaaata agggccaatc atattaaaaa tggctccttt
    18961 aactttatcg gtggttggtc ttgttgtttt tcctgccaat gttttcagcg gtcttccgcc
    19021 ataatttcct gatactactc tcatgaaaat aattatatca caaaatttca aatggagagc
    19081 cgaatctccc tgtaagcctt ggtctaaagg ttctgtcagt aaaaattttc ttattatttt
    19141 actgacaaaa aaataagttt ctcaaatcag aattttattc taacttttga aacttatttt
    19201 tacctatatt taactcatga atgactttca tgcatccgaa ttgctcgtag tgagggcagc
    19261 acacctaata caataatgaa aaacatgaag atggtcattc caatatttcc ataaagactt
    19321 gagagagaca caaggattcc tgacaagacc gaagcgatag gctgagtcac tgaaaaagct
    19381 cctgtataag ttcccacttg gtctccatcc attaaatcgg ctcgcagagc ctgtgaaaat
    19441 ggaaccaaaa tcatttcacc gattgttgct atcaatgctg caatcagttc ccaagttaaa
    19501 tcacgaccaa gaaatgcaat catgaagccc aaaccttgca aaataattcc aatggatatt
    19561 ccactacttc gtgaccagtt tttggttagt ttgttgactc tccccataaa taatacgatg
    19621 actaaggtat tgaccattag gaaaattgtc agcatccgtt gtccataaac ttcaattcca
    19681 aaaatccttg ctgttctaaa actatcactc aaatggactg gaagataata atcaatttga
    19741 ttaaaaatca tcgcaataaa gaccgaagca aataaataat acatgaaaat acggtcttta
    19801 gcaactgtga aataggcttt aataatgttt gattcttgct tatgctgctg agtatctgga
    19861 ttgaaggatt catcaatcca aaaaattaca accaaacaac taacgatttc ttcaattgtg
    19921 atagctaaaa gtaaccaaac caaataatct cggaaaaacc aacctgaaag tcctgaacca
    19981 atcatgattg caaaattgat aatccaatat tgaatactat aaacgactcg ccgatttcca
    20041 cttgttgtca aatctacaat catcgcttga cttgcggtgt taaaaaagcc aaaaccaaaa
    20101 ttaataataa gaaatcctaa aaaagtgacc caaggattga agtaaaaaga tgagtttgca
    20161 aatgttgcta aagctccacc aaaaccagta atggcagttg agaaaatcat cacaggtctt
    20221 cgtccctgaa cgtcggacaa atgaccagca taaagcccaa ccaagaaaac catgactgaa
    20281 ctaatgacta aaagtaatcc cgtgattccc gctcccatat atttattgta gtaaattgtc
    20341 attgagccac ccactgtact aaagcaaagc gtcccaaaaa aattcatgat taaacgaatt
    20401 ttaagtgttg gatgtaatcc aaaaaaatct ttcattttat ttctttctgt tttttttcaa
    20461 taaaaaacct accttgactc cttttcaaga taaattcttt tttttagagg tcattttttt
    20521 aattaatttt tgttttctgg tgtctattta cagcaataag cactaaaata atcgctagaa
    20581 cttcagttaa tgctaagact aaagaaactc ctgttgcttt aatcattggt gaaatcgaaa
    20641 caagtaaacc ggcaagaatg gaggcaatcg gcatcttaat tgcggcaacg ccattgtaag
    20701 aaccaatttt ttctggattc atcaaatctg cacctaaagt ttgaacactt ggtgtataaa
    20761 caatttcacc taaagtataa acaataccgg caatgaaaat aggcgtaaac gtcgttgtca
    20821 aaaatgaaaa aatcatccca attgccataa ataaacttcc ccaaataaat cctttttggt
    20881 gtgaccagtc cttggtcaat cgatttaggg tggtcattaa taggacgact aatacacaag
    20941 ctaaaatcaa ataaatcgta agcatccgtt gtccatagat ttcaaaacca aaaaaagtga
    21001 ttgttttaaa actatttgat aaatgaacag gtaaaaaatt atcaaattgc atgataataa
    21061 aagtggtcgc aatattagca cccataaaaa tcatgtaagt tttatcttgt agcactgtct
    21121 tataggcctg aaaaatattt tctgcttctt ctttggcctt tacaatcggt ctaaaagtct
    21181 cagtcattac aaaagtggtt aagaaaaatg agactaagac agttaaaagt aatatcacta
    21241 aaagtgcttc aaatgctggt ctaaaaagcc aagcacctaa tgctgctcct aaaataactg
    21301 acaagttttg cgcccaataa tccaacataa aaacaacttt acgattttca gcatttgatg
    21361 catcaataat catggcattt cctgcagtaa tcacaagatt ataaccaaaa ctaatcagca
    21421 aaaaagcaat aaaagttgac caaggattca cgtgacctgg taagtttgag gcaatggcta
    21481 aaagagctcc caaaagttga atcactgtcc caaaaaccat cactggtttt cgaccatttc
    21541 ggtcagcaaa aaaacctgca agaattcctg cgacaaaagt ggctactgca gataaggcaa
    21601 gcaaaatccc tgtaattgca cttcccaaat gttgattata ataaatggtc attgaagaaa
    21661 aaacggtgcc atatgaaaag gcacctaaaa aaacaattcc taaacggagt tgcaaatttt
    21721 tgtctaaatt ccaaaactct ttcatattat tccttaaatt cttttaaatt ttctaaattt
    21781 attaatttat ctataattgt agcatattta tacttctaaa actagatgaa ttacagcttt
    21841 atcaaaataa ttcttctact tatatcaatt tttgttaaaa taaactgtaa ccaaacttaa
    21901 tttgatttgt tatatatatg agagaggagg agatggtgaa tttaaaagaa tatgaaaatg
    21961 acgtcaatga ttatgcgata gaaatcacta aataccttat ctctcgtgga agtcagttgg
    22021 ttgatgccga agatgccgta caggatactc tggttaaaat tttaagtctg gatattttca
    22081 ttgaacctga caaattacgg gcttttatgt atcgaacatc tatccgaact tatattaata
    22141 gttataatcg gagtaaacat tatcaaaaaa ttattaaaaa tttggaaaaa gaattggaaa
    22201 cagcagcttt tttagttgag tctagcccac ttccaaaaat cattgaacaa cttccacctt
    22261 attataaaaa gcttttaaat gcatactatt acgaaaatag ttcgactaaa cagcttgcag
    22321 aatattttga atgtagttta agcaaaatca aaatcgacct ttatcgagct cgaaaaaagc
    22381 ttaaaaaaca acttgaaaaa gctggttatg accagtggct cctctaatcg tctcatgaaa
    22441 ggatttaaaa atgcatactc tcttaatttt cccttacctt gttttagcta tcactttatt
    22501 tttcggactg attcgtctgt ttatttttgc gatcaataaa acacggcaca aacttcaaac
    22561 aactgaatct atttctaatc tcaacaaaga ttttcataat tttgccctaa aaacaaaaat
    22621 aaaacgttgg gggttaacta cttggattgc tttgactgta ttttcagcat ttatagttgt
    22681 tggttggcga gtgaactccg ctatcatgga aaaaaatttc tttaaaactt ttgattactc
    22741 taccgctatt ttcaccgctt ccgccccaaa tgttgcttat aataatcaga ttatcgataa
    22801 ttatggcgtg tttagttcta atcttcattc agatacttat aaagatattg atggttatcc
    22861 tgtgccctgg gaatcttata atttttcctt taatgtttcg aatgttgggg gcttaaatct
    22921 taataccttg agtccgtcag taaattcaaa tgcctatttt acccaaacaa ctaatcaaaa
    22981 aattgctagt tttttctcta caaataccaa ctacaaatcg aaagattatt atggaattct
    23041 gcctacccat gatgcagaca aaatttcaca actttcaaac cacgtggcgg aagttgctgt
    23101 cacctttgat aaagcttata gttacaacga aatccaaaaa atgattccca aaaatctttt
    23161 aattaattgg tattggattg gttacaatga ttcgaaatct cttgatgctg ctggacaaac
    23221 aaactggttt ggcttgatga gtaacagcaa ttatgctgaa aatggtaata attcacagct
    23281 cactggaaaa ttagacaata ctacttatca agattttaaa aagtcagtaa ctgctattgc
    23341 gaaaaagaac caaatcacaa ttaacgactt tagcccaagt aaagatgcac ttaaacaagt
    23401 taaaaaatat cctactctta aatcagctaa attttcgggg gtcattttaa caggacaaac
    23461 taagaatttt gcgaattttg ataaaaattc ttgggtttat gcaagtaatg ttggcctcac
    23521 agtagaactt cgccctgata ttaagccact taaataataa ttttactgac aggatttatc
    23581 agtaagaaat gaatacaaaa aatcactgac agaaatcttg tcagtgattt ttatgacact
    23641 tttaatcaaa gattaaaggc ggtcattcaa ttctttgctg agttcttcaa atcctggttt
    23701 accaagaaga gcgaacatat ttttcttgta agcttcaaca cctggttggt tgaatgggtt
    23761 aattccgttc aagtaaccag aaacaccgat agcaagttca aagaagtaaa ttgcatatcc
    23821 aagtgtgaat tcgtcttgtt caggcaatgt cacgatcatg tttggaacat ttccgtcagt
    23881 gtgagcaaga agcacgccgt cagctgcttt tttgttaacg aagtcaacat ctttaccttg
    23941 caagtatcca agtccatcaa gatcagcgtc aagttctgga atgttgatgt ttttacgtgg
    24001 tttttcaata cggattgctg tttcaaaaac agtacgtgtt ccttcttgaa tccattgtcc
    24061 taatgagtga aggtctgttg agaagttagc tgaagttggg taaattcctt tttggtcttt
    24121 cccttctgat tcaccagcca attgtttcca ccattctgag aaatattgaa ggcttggttc
    24181 gtaattgatc aagatttctg agaatttacc tttacggtaa aggatattgc gaagtgcagc
    24241 ataggcgtaa gcatcatttt catgaacatt tgtagaagtg tattctttac gcgcagcgtt
    24301 agcaccttcc atcaaagctg tgatatcagc acctgaagct gcaattggca aaagtccaac
    24361 agctgtcaat actgagaagc gtccaccaac tgaatctgga acaacaaaag tttcccagtt
    24421 gtttgcgtca gcattaactt ttacagcacc tttttcttta tcagttgttg cgtaaatacg
    24481 tttgtttgct tcttcacgac cgtatttttt aactaacatt tcttcgaaga cacggaaagc
    24541 aatcgctggt tctgttgttg tacctgattt agagattaca tttacagaga aatctttgtc
    24601 agcaacgtaa tctacaaggt cagccaagta tgatgaagaa attgagttac cagcataaag
    24661 aatacgtggt gctttacgtt cttcggcagt ttgcaagtta acaaagctgt tgctcaaaaa
    24721 gtcaattgct gcacgtgcac cgaggtatga accaccgata ccgataacaa taagaacttc
    24781 tgaatcagat tgaatttttt tagctgcttt ttgaatacga gcaaattctt ctttgtcgta
    24841 atcttcagga aggtcaagcc atccgatata atcgctccca gcaccttttc cttcgtggag
    24901 caatttagct gccccgtcga tttgccattg gatttcgtct aattcatttt cagctacaaa
    24961 tggagtgagt tttgaatagt caaatttaat atgagccatt ttaattcctt tcaatttctc
    25021 gctttttacg agaatttagc tattgaagaa cgacaacttt tgcattgttt tatcttcgaa
    25081 ttttctagtt cattttatca ctttttcggc tttttaacaa tactaaaggt tatgtaagcg
    25141 cttatttgtt tagctttcta tctgtgaaac ttttccagct ttgggacagc tttttttata
    25201 aaaatttagt ttaagatttc aatgaatatt tattgttatt aaaagattta ctgataagct
    25261 aactcctaac acttttaagg gtgtcaaatc tctttgacga ctgacaaatc agtctttcat
    25321 gtaaattttt gctaaaatat taatgatgaa atatacattt gaaattgacc ttgaccgtta
    25381 taaaaatcta gcccaacaaa aacaaaagac acataagaaa tttttagctg gacttgccaa
    25441 aaaaccacca aagcaattag ataaaatcgt taaagaagtt catgaagagg tttttttaga
    25501 aattgattgc accaaatgtg ctaattgttg caaaacctta ggccctcttt ggacagaggc
    25561 cgatattgaa cgcgtcgcca aacatttaaa aatgaaagtg agtgactttg aagtcgcata
    25621 tctccgaact gacgaagatg gtgacaaagt ttttcaaacc atgccttgtc cgtttcttgg
    25681 ttctgacaat ctctgtagca tttacgaagt tcggcctaaa gcttgtcgcg aatttcccca
    25741 tactgaccgt aaaaagattt atcaaatcaa taatttaacg ataaaaaata cactttactg
    25801 tccagctgct tatgaatttg ttgagaaatt atcttataga ctcaaataaa aattactgac
    25861 aggtctgtca gtaatttttt tattatgcca aaagttcttt caaagcttct tttgtatctg
    25921 tcagtgaatg ccccaaggct ttttcaaaat ctttagattc cacatctaaa tcttttgctt
    25981 caatatcttt ttggaagccg aggaaaagtt ccgctacaaa atctggaagt ccagtttcaa
    26041 ctaaatgact gacaaaagtt ttgtcatcag cagcgactac ttcaaattcc ttatcagaaa
    26101 ctgcttttag tgcttgagca agttcggcgt aagtcaatat ttttcctgaa agctccaaaa
    26161 cttctggaaa atctgctcca gcaagtgctt ttgctccaac ttctgcatat tcgcgtttca
    26221 aagcccagcc cactttacct gttggtgcat tgtatacaaa ttttccagtt gaaagtgcgg
    26281 cagcaataat tggcatttca ttttcaaagt accagttatt acgtaaaaat gtgtgagcaa
    26341 ttcctgattt tttaatcgcc ttttcagtat agatgtggtc agcagctaag tcacttgttg
    26401 ccctttctgc ttgaggaaaa cttgtataag caatataaga aa
//
