LOCUS       NC_013656              21937 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Lactococcus lactis subsp. lactis KF147, complete sequence.
ACCESSION   NC_013656
VERSION     NC_013656.1
KEYWORDS    RefSeq.
SOURCE      Lactococcus lactis subsp. lactis KF147
  ORGANISM  Lactococcus lactis subsp. lactis KF147
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B., Wels,M., van Hijum,S.A.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Complete genome sequence of Lactococcus lactis subsp. lactis KF147,
            a plant-associated lactic acid bacterium
  JOURNAL   J Bacteriol 192 (10), 2649-2650 (2010)
   PUBMED   20348266
REFERENCE   2  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Starrenburg,M.J., Boekhorst,J., Renckens,B.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Genome-scale genotype-phenotype matching of two Lactococcus lactis
            isolates from plants identifies mechanisms of adaptation to the
            plant niche
  JOURNAL   Appl Environ Microbiol 74 (2), 424-436 (2008)
   PUBMED   18039825
REFERENCE   3  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Complete genome sequence of Lactococcus lactis ssp lactis KF147
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-DEC-2009) NIZO Food Research, Kluyver Centre for
            Genomics of Industrial Fermentation, PO Box 20, Ede 6710 BA, The
            Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000025045.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 01:08:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,639
            CDSs (total)                      :: 2,548
            Genes (coding)                    :: 2,493
            CDSs (with protein)               :: 2,493
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 25 of 55
            Pseudo Genes (incomplete)         :: 23 of 55
            Pseudo Genes (internal stop)      :: 14 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:59:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1342969
            Orig. end                         :: 1364906
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001834.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria source: Dr. W.J. Kelly, Agresearch Limited, New Zealand;
            william.kelly@agresearch.co.nz.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21937
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="5"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21937
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21937
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11937](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11937)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    427..443
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.04"
                     /tool="antismash"
     gene            complement(1000..1236)
                     /locus_tag="LLKF_RS06540"
                     /old_locus_tag="LLKF_1294"
     CDS             complement(1000..1236)
                     /NRPS_PKS="Domain: PP-binding (4-69). E-value: 3.6e-14.
                     Score: 44.8. Matches aSDomain:
                     nrpspksdomains_LLKF_RS06540_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="LLKF_RS06540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1294"
                     /product="acyl carrier protein"
                     /protein_id="WP_012897841.1"
                     /sec_met_domain="PP-binding (E-value: 2.3e-11, bitscore:
                     41.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLEAIKEIVARLSPLSVSEIKDNDKLADIGVDSLSTVEIIVGL
                     EEKFNLEFEDSTLDLGKLSSIQGILKLVNETLG"
     aSDomain        complement(1030..1224)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LLKF_RS06540_PP-binding.1"
                     /evalue="3.60E-14"
                     /label="LLKF_RS06540_PP-binding.1"
                     /locus_tag="LLKF_RS06540"
                     /protein_end="69"
                     /protein_start="4"
                     /score="44.8"
                     /tool="antismash"
                     /translation="EAIKEIVARLSPLSVSEIKDNDKLADIGVDSLSTVEIIVGLEEKF
                     NLEFEDSTLDLGKLSSIQGI"
     gene            complement(1267..2334)
                     /locus_tag="LLKF_RS06545"
                     /old_locus_tag="LLKF_1295"
     CDS             complement(1267..2334)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="LLKF_RS06545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1295"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_012897842.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 3e-25, bitscore:
                     86.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKLLLIADATYSGEKIKIEPTDSQEFLMGWIIMNRCSSIAYKN
                     LDLETIHRDNLMALNVLKSSDEKRAKIFQKNLFSISKLLETVDFNYSFLKGAFLSTALY
                     KLGDRTSKDFDILIESKNVSALQKILLADGFVQGWPGADDQSIIAATRRQIIESRMNFG
                     ETVPFIKIVDGVPVSVDVNFSVDFKPDEGVGLVPKLLNNVEEVSGEGFEFKSLSKVDFL
                     IHLCCHLYKEATTYDWVKSRRDLDIYKFSDINVFLQKFGGADFFENLAQHIKEYGVEKE
                     CYYTFKNASMIFPKINDIENFGKCLIEIEPENLDYMKEIIYPREKKMYYYNESFLDWLM
                     SNDRTSLLKEKIQHD"
     gene            complement(2974..3618)
                     /locus_tag="LLKF_RS06550"
                     /old_locus_tag="LLKF_1296"
     CDS             complement(2974..3618)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570415.1"
                     /locus_tag="LLKF_RS06550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1296"
                     /product="transporter"
                     /protein_id="WP_012897843.1"
                     /transl_table=11
                     /translation="MIRSECLKLKNSSGFYLVFLFTLLEILTIPIYLSFGRSHVSMTDL
                     SLMIFLFFPLLVTILSILIFEQESLANHFQEINVNKKSSRIWLSKLIVVDFLLFFPSAM
                     IWIITGVSQGIGQQGMMIATASWLMAIFLNHFHLLLTFIINRGGSMIIAIIEILFIIFA
                     SNKVLLAAYWCPIALPVNFIITGRCAYLIAAVGWIVLSTIILVALSKKKIR"
     gene            complement(3605..4333)
                     /locus_tag="LLKF_RS06555"
                     /old_locus_tag="LLKF_1297"
     CDS             complement(3605..4333)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864241.1"
                     /locus_tag="LLKF_RS06555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1297"
                     /product="lantibiotic ABC transporter permease"
                     /protein_id="WP_012897844.1"
                     /transl_table=11
                     /translation="MKRIIASESIKLKKSGTLRLVLIIPFVTLFIAFLMGGIQIFSVFS
                     IYWWEAGFLFLLMCLLFLYDKKSEEQAGNFQNVKWKNLSWKIHLAKMLLIWLRGILASI
                     VLIVLLYLVAFVFQGIVVVDFMKVSVALIAILLATSWNLPFIYLIFKWINTYVLLAANI
                     LICLIIAPFVAQTPVWFLLPYTYHYKVTESLLNIKPSGDLLTGKINFSIWEVLLPVGLS
                     IVVTIGVSYLLKGVIEHDKK"
     gene            complement(4335..5012)
                     /locus_tag="LLKF_RS06560"
                     /old_locus_tag="LLKF_1298"
     CDS             complement(4335..5012)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897845.1"
                     /locus_tag="LLKF_RS06560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1298"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012897845.1"
                     /transl_table=11
                     /translation="MQVKIQNLSKTYKEKQVLQDISFDIKSGTVCGLLGVNGAGKSTLM
                     KILFGLISADTGKIFFDGQEKTNNQLGALIEAPAIYMNLSAFDNLKTKALLFGISDKRI
                     HETLEVIGLAETGKKRAGKFSLGMKQRLGIGMAILTEPQFLILDEPTNGLDPDGIAELL
                     NLILKLKAKGVTILISSHQLHEISKVASQIIILNKGKICYNHANNKEDDIEQLFFKIVH
                     GGM"
     gene            complement(5111..6454)
                     /locus_tag="LLKF_RS06565"
                     /old_locus_tag="LLKF_1299"
     CDS             complement(5111..6454)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864239.1"
                     /locus_tag="LLKF_RS06565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1299"
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="WP_012897846.1"
                     /transl_table=11
                     /translation="MGKKYSMRRRIWQAVIEIIIGTCLLILLLLGLTFFLRQIGQISGS
                     ETIRLSLDSDNLTISDIERDMKHYPYDYIIFDNDTSKILGGHYVKSDVPSFVASKQSSH
                     NITEGEITYTYSSNKHFSVVLRQNSMPEFTNHTLRSISYNQFTYLFFFLGEIILIIFSV
                     YHLIREFSKNFQAVQKIALKMGEITTFPEQEESKIIEFDQVLNNLYSKSKELAFLIEAE
                     RHEKHDLSFQVAALSHDVKTPLTVLKGNIELLEMTEVNEQQADFIESMKNSLTVFDKYF
                     NTMISYTKLLNDENDYKARISLEDFLIDLSVELEELSTTYQVDYQLVKKTDLTTFYGNT
                     LALSRALINIFVNACQYAKEGEKIVSLSIYDDEKYLYFEIWNNGHPFSEQAKKNAGKLF
                     FTEDTGRSGKHYGIGLSFAQGVALKHQGNLILSNPQKGGAEVILKIKK"
     gene            complement(6447..7133)
                     /locus_tag="LLKF_RS06570"
                     /old_locus_tag="LLKF_1300"
     CDS             complement(6447..7133)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014734918.1"
                     /locus_tag="LLKF_RS06570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1300"
                     /product="response regulator transcription factor"
                     /protein_id="WP_038603442.1"
                     /transl_table=11
                     /translation="MYKILIVDDDQEILKLMKTVLEMRNYEVVTHQNISLPLDITDFQG
                     FDLILLDIMMSNIEGTEICKRIRREISTPIIFVSAKDTEEDIINGLGIGGDDYITKPFS
                     LKQLVAKVEANIKREERNKHAVHVFSEIRRDLGPITFYLEERRVCVNGQTIPLTCREYD
                     ILELLSQRTSKVYTREDIYDDVYDEYSNALFRSISEYIYQIRSKFAPYDINPIKTVRGL
                     GYQWHG"
     gene            complement(7202..8560)
                     /locus_tag="LLKF_RS13755"
                     /pseudo=""
     CDS             complement(7202..8560)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="LLKF_RS13755"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="S8 family serine peptidase"
                     /pseudo=""
                     /sec_met_domain="Peptidase_S8 (E-value: 2.8e-25, bitscore:
                     86.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYVTNNGESYVLYQPSKKISVGIIDSGIMEEHPDLSNSLGNYFK
                     NLVPKGGFDNEEPDETGNPSDIVDKMGYGTEVAGQITTNGNILGVAPGITVNIYRVFGE
                     NLSKSEWVARAIRRAADDGNKVINISAGQYLMISGSYDDGTNDYQEYLNYKSAVNYATT
                     KGSIVVAALGNDSLNIQDN"
     gene            complement(8657..9265)
                     /locus_tag="LLKF_RS13760"
                     /old_locus_tag="LLKF_1303"
     CDS             complement(8657..9265)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LLKF_RS13760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LLKF_1303"
                     /product="hypothetical protein"
                     /protein_id="WP_038603445.1"
                     /transl_table=11
                     /translation="MKKILGFLFIVGSLGLSATVHEETTNSQQLPSNNINTELINHNSN
                     AILSSTEGSTTDSINLGEQSPAVKSTTRTELDVSKTGADKILLQTSAAQKETKVSLEET
                     QVSSELSKRDSITNKEAVPVSKDELLEQSEVAASTSSIQKNKIIKNEKNRANFVTSSQL
                     IKEKLSNSKDASGVTDNSTSPLYYFKAKEGVPLRQHLKN"
     misc_feature    9250..9265
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.31"
                     /tool="antismash"
     gene            complement(9267..10004)
                     /locus_tag="LLKF_RS06585"
                     /old_locus_tag="LLKF_1304"
     CDS             complement(9267..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570409.1"
                     /locus_tag="LLKF_RS06585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1304"
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="WP_012897848.1"
                     /transl_table=11
                     /translation="MRKYLILIVTLLGITGLTGCYQTSLKKVRFDEGSYNNFIYDNKSY
                     FVTDKEIPQENVNNSKAKFYKLLIVDMKSEKILSSSNKNSVTLVLNNIYEASDKSLCMG
                     INDRYYKILPKSEKGEVKALRLQNFDVTSDISDDNFVIDKNDSRKIDYMGNIYSISDTT
                     VSDEELGEYQDILAEVRVFDSVSGKSIPRSEWGRIDKDGSNSKQSRTEWDYGEIHSIRG
                     KSLTEAFAVEINDDFKLATKVGN"
     gene            complement(10001..10834)
                     /locus_tag="LLKF_RS06590"
                     /old_locus_tag="LLKF_1305"
     CDS             complement(10001..10834)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="LLKF_RS06590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1305"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_235187778.1"
                     /sec_met_domain="LANC_like (E-value: 2.5e-46, bitscore:
                     155.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEGLSGILSYLLLINDEQYDDLKMLIINFLSNLTKENKGLISLY
                     IKSENQMSQSESEMYPLGCLNMGFAHGLAGMGSILAYAHKKGYSNVASLSALRNIIFIY
                     EKFELERKNKFLWKDGLVVDELKKEKVIREACFIRDAWCYGGPGISLLYLYGGLALDND
                     YFVDKAEKILESAMQRKLGINSYMICHGYSGLIEICSLFKRLLNTKKFDSYIEEFNVNS
                     EQILKEYGDESGMGFLEGISGCILVISKFEYSINITYWRQALLLFDDFFKGGKWK"
     gene            complement(10831..11937)
                     /locus_tag="LLKF_RS06595"
                     /old_locus_tag="LLKF_1306"
     CDS             complement(10831..11937)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="LLKF_RS06595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1306"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_235187779.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.3e-47, bitscore:
                     157.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.7e-06,
                     bitscore: 25.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKSSFKAQQFLVRNTILSPNDKRSFTEYTQVIETVSKNKVFLEQ
                     LLLANPKLYDVMQKYNAGLLKKKRAKKLFESIYKYYKRSYLRSTPIGLFSETSIGVFSE
                     SSQYDLTGKTTKSISLDTQWLIRLVHQMEIDFSKKLSFIRNNANYEFGDRVFQVYTINS
                     SELEEVNIKYTNVYQMISKFCENAYQRYEDICETVTVCYGEKYRELSEQYLDSLIVNHY
                     LISNLQKDLLSDFSWDTFLIKVEAIDDDKKYIITLKKIQKFIQEYSEIEIGEGIEKLKE
                     IYQEMSKILKNDNYVQIDLISDSEINFDVKQKQQLEHLAEFLGNTTKSVRRTYLDDYRD
                     KFIEKYGVDQEVQITELFDSTLLLLIMT"
     aSDomain        complement(11251..11508)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LLKF_RS06595_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="1.90E-08"
                     /identifier="RREFam001.1"
                     /label="LLKF_RS06595"
                     /locus_tag="LLKF_RS06595"
                     /protein_end="229"
                     /protein_start="143"
                     /score="25.9"
                     /tool="antismash"
                     /translation="RNNANYEFGDRVFQVYTINSSELEEVNIKYTNVYQMISKFCENAY
                     QRYEDICETVTVCYGEKYRELSEQYLDSLIVNHYLISNLQK"
     gene            complement(12069..12266)
                     /locus_tag="LLKF_RS13210"
                     /old_locus_tag="LLKF_1307"
     CDS             complement(12069..12266)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570405.1"
                     /locus_tag="LLKF_RS13210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1307"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_080513130.1"
                     /sec_met_domain="TIGR03731 (E-value: 3.1e-21, bitscore:
                     72.3, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 1.9e-05, bitscore:
                     21.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYKEALETSTKDFNLDLISVSKKDSGVSPRITSISLCTPGCKTG
                     ALMGCNMKTATCNCSIHVSK"
     CDS_motif       complement(12174..12266)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNYKEALETSTKDFNLDLISVSKKDSGVSPR"
                     /locus_tag="LLKF_RS13210_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12069..12173)
                     /prepeptide="core"
                     /locus_tag="LLKF_RS13210_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="23.80"
                     /molecular_weight="3313.0"
                     /monoisotopic_mass="3310.6"
                     /core_sequence="ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNYKEALETSTKDFNLDLISVSKKDSGVSPR"
                     /leader_location="[12173:12266](-)"
                     /alternative_weights="3331.0"
                     /alternative_weights="3349.0"
                     /alternative_weights="3367.0"
                     /alternative_weights="3385.1"
     gene            <12411..12491
                     /locus_tag="LLKF_RS13765"
                     /pseudo=""
     CDS             <12411..12491
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634700.1"
                     /locus_tag="LLKF_RS13765"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VSIASVVIKLGHSSMSKAQETYLHVI"
     gene            complement(13002..13175)
                     /locus_tag="LLKF_RS13770"
                     /old_locus_tag="LLKF_1308"
     CDS             complement(13002..13175)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LLKF_RS13770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LLKF_1308"
                     /product="hypothetical protein"
                     /protein_id="WP_012897850.1"
                     /transl_table=11
                     /translation="MLDEPQIKKRGRNLDKKHSDNYNLESIIERIKTNEISLTVDEVVE
                     CYEKNRRSKAIF"
     misc_feature    13332..13346
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.78"
                     /tool="antismash"
     gene            complement(13737..14474)
                     /locus_tag="LLKF_RS06600"
                     /old_locus_tag="LLKF_1309"
     CDS             complement(13737..14474)
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003136374.1"
                     /locus_tag="LLKF_RS06600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1309"
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_012897851.1"
                     /transl_table=11
                     /translation="MHSEMVQLLGEFLGTFILILLGNGVVSGVVLNKTKATGAGWVAIT
                     LGWGFAVMMGVYISGFMSPAHLNPAVTIAMAMIGSFSWSLVLPYIIAQMLGAMVASIIL
                     YLMFYPHYAETKNPADILGTFSTGPALRHTGSNLISEIVGTAVLTTGILAFGQYTITQT
                     SGVSPLLVGAIITAIGLSLGATTGYSLNPARDLGPRIMHAILPIKGKGDSDWSYAWIPV
                     LGPIIGGSLGALLFNMVIQFASK"
     gene            complement(14527..16356)
                     /gene="glpO"
                     /locus_tag="LLKF_RS06605"
                     /old_locus_tag="LLKF_1310"
     CDS             complement(14527..16356)
                     /GO_function="GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA]"
                     /GO_process="GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glpO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014024630.1"
                     /locus_tag="LLKF_RS06605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1310"
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="WP_012897852.1"
                     /sec_met_domain="DAO (E-value: 1e-54, bitscore: 183.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFSKKTRQEAITKVQNEEMDLLIIGGGITGAGLALQAAATGMKV
                     SVLEMQDFSEGTSSRSTKLVHGGIRYLKNFDVEVVSDTVSERAVVQSIAPHIPKPDPML
                     LPIYNDEGKTTFDMFSVKIAMDLYDRLAGIDEGSPYANYTISPEEVLRREPLIKKKGLQ
                     GAGVYLDYRNNDSRLVIDNIKKAVEDGAKAISKMKVIDFIYTDGQISGVRARDLLTDEV
                     IEVKSKLVINTSGPWVDKIRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGK
                     HDKRMVFAIPRENKTYFGTTDTDYHGDFTDPKVTQEDVDYLLDVINFRYPGANITINDI
                     EASWAGLRPLLGGNSGSDYNGGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNM
                     ESSLSEKGDAPSSVSRGSSLERESDGLITLAGGKITDYRKMAAGAMELICQLLVEDFDL
                     KYEPIDSKKYQISGGEFDPTKVEEVVAENMKIGVVAGLTEEEAKYIADFYGMNALQVFA
                     YASEMKPYEGLSLAESARLRYALEDEMILTPVDYFLRRTNHILFMRESVDTIKVHVVNV
                     IAGFLGWSVEEKAEQEKALEKALRESDLSDLKK"
     gene            complement(16392..17888)
                     /gene="glpK"
                     /locus_tag="LLKF_RS06610"
                     /old_locus_tag="LLKF_1311"
     CDS             complement(16392..17888)
                     /EC_number="2.7.1.30"
                     /GO_function="GO:0004370 - glycerol kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glpK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /locus_tag="LLKF_RS06610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1311"
                     /product="glycerol kinase GlpK"
                     /protein_id="WP_012897853.1"
                     /transl_table=11
                     /translation="MTETSYIMAIDQGTTSSRAIIFDKHGKHIGSSQKEFTQYFPKEGW
                     VEHDANEIWNSVQSVIAGAFIESGIKPVQVAGIGITNQRETTIIWDKKTGIPIYHAIVW
                     QSRQSSNIANGLKDAGHDELFHKKTGLIVDSYFSATKIRWILDHVEGAQERAERGELLF
                     GTIDTWLLWKLTDGDVHYTDYSNASRTMLYNIHELKWDEEILKILNIPASMLPEVKSNS
                     EVYGVTKGFHFFGSEVPISGMAGDQQAALFGQMAFEPGMIKNTYGTGSFIVMNTGEKPH
                     ISKNNMLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLKMLDRASDSEEVALQSMSQ
                     DEVYVVPAFVGLGAPYWDQEARGAMFGLTRGTTKEDIVKATLQGIAYQVRDVVSTMKED
                     TGIDMSVLKVDGGAANNEYLMQFQADILNIPIQRAGDLETTALGAAFLAGLAVGFWKDL
                     EELKESYEPGKIFQTQMQKERREELYAGWKKAVNATRAFK"
     misc_feature    complement(17903..17914)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            complement(18256..19722)
                     /locus_tag="LLKF_RS06615"
                     /old_locus_tag="LLKF_1312"
     CDS             complement(18256..19722)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019292762.1"
                     /locus_tag="LLKF_RS06615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1312"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_012897854.1"
                     /transl_table=11
                     /translation="MNIEVLLEKKEQIQVKILRQLFLKHDKLTAQELCDWVNLSRPSVQ
                     SYLEDISYIGRMLGKPMEVIRQNNKLVLNMPESQTLDEVISFLIQDSIKYRLILLFLEQ
                     KNYMIFELAELLLLSESTLFRKIKELNKLLLEFDIQIKNNKLIGEESQIRYFYYLLFDS
                     LHPKFRPDLLQVTKFQVEFVRQLEETLKVNFSESSKDKLYRWLAITERRRKLTDIQITK
                     SLEMKIIYQDDHLYQLLDSLFYQHIYDNQSKDNCETIFFYSFLQSFFILDKESYYRFDI
                     YRSKKIPTVLLNISLRERMLNHYRPHRLGFEEEKSISYQLAQVNNKFTFFQGSLFTKIQ
                     EDLMLHKQNWVDKSFQDLLDNLKDIALSYIPKEQDLPELIFGYRNALMLLELLSAQQLT
                     VAYDLSDTPAYQIPMEHYLKNHLRPVEKIKLEHYQESQSYDLLISSKRNDSRKFVYILS
                     EFSSDYDFEELLSRIENLKKEKFQKKAILN"
     gene            complement(19992..20699)
                     /locus_tag="LLKF_RS06620"
                     /old_locus_tag="LLKF_1313"
     CDS             complement(19992..20699)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897855.1"
                     /locus_tag="LLKF_RS06620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_1313"
                     /product="hypothetical protein"
                     /protein_id="WP_012897855.1"
                     /transl_table=11
                     /translation="MKLILSSILLGFGGFDPVGAVLIMAALANGTKKKQVYLFSLMALL
                     STVVFGLIFSYGTSISLNYFINIMNHIPDMAYVFTGFLISIVCVAWFIRSTLLKGNKER
                     VDDQKEAKFMKFAKRSMPLAGFIFGFWAMSDPTFWAVVALSAKEGNILLTILCLTIWML
                     LGQIPLYTLVVSLIFNVYEKLIKIASRYLDKNNRRKKLSNVTRIIISLFILGIGIYFFI
                     DSLVYLLKGIWLY"
ORIGIN
        1 tgaattgtca gacacttctt cgtctgtatc tttatcacaa atttttattt gagttgattt
       61 tagtagaatc cctactgact caggaaactc atcgaaatat tggggcggta ggtatgagat
      121 tcgaggggaa gcttctgttt gcccataaac attgaaaatt tttgtttctt taaaaacatc
      181 tctaattatt acagcagatt ctttagtcaa gcactcgcca ctaatcgcaa tttttttaag
      241 aggcaatatc ctctttgtcc ttccaagaag tttagccatt tgtttgaaga gtgtcggagt
      301 cccaccacaa atagaaatat tatgactttc aatttgtgaa atcagtttca tcggattaaa
      361 atcgctattg aaaaattcaa tatttcctcc ttggctcaaa gcgactagaa attctcccgt
      421 aaaagctgca caatgataga gcggtcgtac aattattatt ttatctgact gagtaatatt
      481 aaaataatta gccgtttcaa caatattcat caaaagtcct tgctctgtca ataggatacc
      541 tttaggttct cctgtagtac cagatgtata aagaatagct gcaatatctg ataatacctt
      601 ttcttgaact acagaaggag aacttccaat acaaatgcca cttgtaattt caaaccttgg
      661 aatactttct tcaacatcag gtttgtttaa atcagtaata agcaaatctg gtaagcaatg
      721 taacagaact tttttatagt gccttttacc ataattgtga gaaagtggta ttggaacaac
      781 acctgcaaac caacaaatca aaatagaaag tgcagtgttc atttcatcac cacataaaat
      841 ggcacatttt gaatgtttgg gaacaatttt cttaagttgt ctccctctga gctgaatgaa
      901 agataatgca ctcccataag taagcttttg attagcacta ctaattaccg aacatggggt
      961 tttcttcaat gtatcttcaa taaatttcca cataaatttt taacctaatg tttcgtttac
     1021 aagtttcaat attccttgaa tgcttgaaag ttttccaaga tctagcgtag aatcttcaaa
     1081 ctcgaggtta aacttttctt ctaacccaac gatgatttca accgttgaaa gtgaatctac
     1141 accaatatca gctaacttat cattatcctt aatctcggag actgacaatg gagacagtct
     1201 agctacaatt tcttttatcg cttctaaatt ttccaattca tttcctctct ctttcctcag
     1261 tagaagtcaa tcgtgttgaa ttttttcttt caataaagat gttctatcat tactcattag
     1321 ccaatccaag aatgattcgt tgtagtaata catctttttc tctcttggat aaatgatttc
     1381 tttcatatag tcaaggtttt caggctcaat ctctatcaaa catttcccaa aattctcaat
     1441 atcattaatt ttaggaaaaa tcattgaagc attcttgaac gtatagtagc attccttttc
     1501 aaccccatat tctttaatat gttgtgctaa attctcaaag aaatcagccc ctccgaactt
     1561 ttgtaaaaat acattaatat cactaaattt gtaaatatca aggtctcgtc ggctcttgac
     1621 ccaatcgtag gtcgtcgctt ctttatacaa atgacaacac agatggatca aaaaatccac
     1681 tttgctcaag ctcttgaact caaacccttc tcctgatact tcttcaacgt tatttaagag
     1741 cttaggaact aacccgactc cctcatctgg cttaaaatca acggagaagt tcacatcaac
     1801 agaaactgga acgccatcca caattttaat aaatggaaca gtttctccaa aattcattcg
     1861 agattcgata atttggcgac gtgttgcagc tataattgat tgatcatctg ctcctggcca
     1921 accttgaaca aatccatcag caagcaaaat cttttgcaaa gcagatacat tcttagattc
     1981 aatcaagata tcaaagtctt tagatgttct gtcaccgagt ttatataatg cggttgatag
     2041 aaaggcccct ttcaaaaaag aataattgaa atcaacggtt tcaagtaatt ttgaaattga
     2101 aaataaattt ttttgaaaaa tttttgctcg tttttcatcg ctgcttttta aaacgttcaa
     2161 agccataaga ttatctctgt gaattgtttc taaatctagg tttttgtagg caattgaaga
     2221 acaccgattc ataattatcc accccataag gaactcttga ctatcagttg gctcaatttt
     2281 tattttttct cctgaataag ttgcatcagc aattaacaat aatttttctt tcatttcttt
     2341 ctcacacttt cttttaccta caaacaattt ggatttatct tgatacataa gccgataatt
     2401 tgttccttgt tactcatatt tttcctttct cgtacaaatt tactctgctc cccccaatgc
     2461 aatcgattgc gtaccgaagc aactgaaagc tttgagtaat tttctcaaag cactttaagt
     2521 atttctggag catccaatca ttacttttgt gtaacaaata ataatcgacg cgcttccatt
     2581 ttttattata cttttttttt ataactttag ttaaataaac attgtcaaat attatttact
     2641 ttttcgtgtc tatttatttg acattagtcc actctttaag aatataattt ggtaaaacaa
     2701 ctatctgatg aatattgctc caggtttggg acaaaagtca aaggcaaaaa cgattaataa
     2761 aacagtaaca attagtttaa agaggagcta ttcaatcttt tgtttgtgtt attttataag
     2821 gggacataaa agaccagaga aaaaaacttc ttaaaagaag tttaaattat tatttatata
     2881 actacttgat agatatatat caagaaaatc cccgaacata ggagataaat aacaaaaatc
     2941 atattatatc gaattatcac aagaaaaaat actttatcta atcttttttt tagataatgc
     3001 cacaagaatt attgtggata aaacaatcca ccctacggca gctatcagat aagcacaccg
     3061 cccagttatt ataaaattaa caggtaaagc aataggacac caataagctg ctaataaaac
     3121 tttattactg gcaaaaataa tgaataatat ttcaataatc gcgataatca tactacctcc
     3181 tcgattgatt ataaaggtca ataaaagatg aaaatgatta agaaaaattg ccatcaacca
     3241 gctagctgtt gcgatcatca ttccttgttg ccctattccc tgtgagactc ccgtaattat
     3301 ccaaatcatt gctgatggaa agaacaaaag gaaatccact actattagct ttgataacca
     3361 aattctgcta ctttttttat ttacatttat ttcttggaaa tgattggcca aactctcctg
     3421 ttcaaagatt agaatagaca aaattgtaac cagtaacgga aaaaacaaaa aaatcatgag
     3481 cgacaaatca gtcattgaaa catgacttct tccaaaagat aaataaatag gaatcgttaa
     3541 aatctctaat aatgtaaaga gaaaaactaa atagaaccct gaactatttt ttaatttaag
     3601 acattcactt cttatcatgt tctatcactc cttttagtaa atacgaaact cctatcgtta
     3661 cgactatgga aagtccaact ggtaataaaa cttcccaaat actaaaattt atcttccctg
     3721 ttaacaaatc tcctgagggt ttgatattta acaaactttc tgtaacttta tagtgataag
     3781 tgtatggtag caagaaccat actggagttt gtgcaacaaa aggggcaata attaaacaaa
     3841 tcaagatatt tgcagctaac aatacgtagg tattaatcca cttgaaaatc aaatatataa
     3901 agggtaaatt ccaagaagtt gctagtaata tagcaatcaa tgccacactt actttcatga
     3961 aatctaccac tacaatacct tgaaacacaa acgcaaccaa ataaagcaaa acaatcaaga
     4021 ctatgcttgc tagtatccct cttagccaaa tcaacaacat tttggccaaa tgaattttcc
     4081 aactcagatt tttccatttc acattttgaa aatttccagc ttgctcctct gattttttat
     4141 catagagaaa aagcaaacac atcaaaagga ataaaaaacc ggcttcccac caataaattg
     4201 aaaaaacact aaaaatctgt attcctccca taagaaatgc tataaataga gtcacaaaag
     4261 ggataattaa taccaatcta agagttcctg atttttttaa ttttattgat tctgatgcta
     4321 ttattctttt catatcacat tcctccatgc acaatcttaa agaataactg ttcaatgtcg
     4381 tcttctttat tgttcgcatg attataacaa atcttacctt tgttcaaaat aataatttga
     4441 ctagctactt tacttatttc gtgcaactga tgactagaaa tcaagattgt cacaccttta
     4501 gctttaagtt ttaagattaa gtttaacaac tccgcaatac catcaggatc caaaccatta
     4561 gtaggttcat caagaattaa aaattgaggt tctgtaagaa tagccatacc aattcccaaa
     4621 cgttgtttca tccctaaaga gaattttcct gctcttttct ttcctgtttc tgccaaacca
     4681 atcacttcta gagtttcatg aattctctta tctgaaattc caaaaagcaa agccttagtt
     4741 ttaagattat cgaaagcaga taaattcata tatattgctg gagcctcgat taaggctcca
     4801 agttgattat ttgtcttttc ttgtccatca aaaaaaattt ttccagtatc tgcagaaatt
     4861 aaaccaaaca aaattttcat caaagttgat tttcctgcac cgttaactcc taataaacca
     4921 cagactgttc cagatttaat atcaaaactg atatcttgta gcacctgctt ttctttatat
     4981 gttttagaaa gattttgaat ttttacctgc attatatttc ctcactttat tttatgttta
     5041 aaaaaagtat ataaaacaat tttcagaatc tattcagaaa caaaaaaagt aatccttaga
     5101 gattactaaa ttactttttt atttttagga taacttctgc cccacctttt tgaggattac
     5161 tgagaattaa gtttccttga tgttttaaag ctacaccttg agcaaaagat agtccaatcc
     5221 catagtgttt cccactacgt ccagtatctt ctgtgaaaaa tagttttcca gcattttttt
     5281 ttgcttgttc agaaaaagga tgaccattat tccagatttc aaaatagaga tatttttcat
     5341 catcataaat actcaaacta actatttttt ccccctcttt agcatactga caggcattaa
     5401 caaagatatt gataagtgct cgacttaaag ctaatgtatt tccgtaaaaa gtggttaaat
     5461 ctgttttttt aactagctga taatccactt gataagttgt tgacaactct tccaactcaa
     5521 ctgataaatc tatcaaaaaa tcctccaggg agattctcgc tttgtaatca ttttcatcat
     5581 tcaaaagttt tgtataacta atcattgtgt taaaatactt gtcaaaaaca gttaaactat
     5641 ttttcattga ctcaataaaa tcagcttgtt gttcatttac ttcagtcatc tctagcagtt
     5701 caatatttcc ttttaatact gttaaaggtg tcttaacatc atgtgaaagt gcagcaacct
     5761 ggaaggataa atcatgcttt tcatgacgct ccgcttcaat aaggaaagct aactccttac
     5821 ttttcgaata taagttattc agaacctgat caaattcaat aatttttgat tcctcttgtt
     5881 caggaaaagt agttatttcc cccatcttca atgcaatctt ttgaacggct tgaaaattct
     5941 tagaaaattc tctaatgaga tgatagacag aaaaaataat gagtattatt tcaccaagaa
     6001 aaaagaaaag gtaagtaaat tgattataag aaattgaacg aagcgtatga tttgtaaatt
     6061 ctggcatact gttttgtctt aaaacaactg aaaaatgctt attgcttgaa taagtataag
     6121 taatttctcc ttctgtaata ttatgtgaag actgttttga agctacaaaa ctaggtacat
     6181 ccgacttgac ataatgtcct cccaaaattt tacttgtatc attgtcaaaa ataatataat
     6241 catatgggta gtgtttcata tcacgttcga tatcagaaat agttaaatta tctgaatcta
     6301 aagataaacg aatagtttct gaaccactga tttgtccaat ttgtcgtaga aagaaagtca
     6361 agcccagtaa caacaggata agtagacaag tacctatgat aatttcaatg acagcttgcc
     6421 atatccgtcg acgcattgaa tattttttac ccatgccact gatacccaag tccccgaacc
     6481 gtttttatcg gattaatatc gtatggtgca aacttactcc taatctgata aatatactcc
     6541 gagattgacc gaaaaagtgc attagaatat tcatcatata cgtcatcata aatatcctct
     6601 ctcgtataaa ctttagaagt tcgttgtgat agtaattcaa gaatatcgta ttcacgacaa
     6661 gtcagtggaa ttgtttgacc attgacacag actcgccttt cttctaaata aaatgtaatt
     6721 ggtcctaaat ctctacgaat ctctgaaaaa acatgaactg catgtttatt gcgttcctct
     6781 cgctttatat ttgcttccac ttttgcaacc aactgtttaa ggctaaaagg cttagtaata
     6841 tagtcatccc caccaatacc taagccgttt ataatatcct cttctgtatc tttcgcacta
     6901 acaaagataa ttggagttga tatttctctg cgaattcttt tacaaatttc tgtcccttca
     6961 atatttgaca tcatgatatc taacaaaatc aaatcaaagc cctgaaaatc agtaatatcc
     7021 aagggaagtg aaatgttttg atgcgtcaca acttcatagt ttctcatttc taatactgtc
     7081 ttcattaact ttaaaatttc ctgatcatca tcaactatta aaattttata caccacttta
     7141 cctccgattg tttagtactc attacttcat tataccattc attctgaaga aatataatct
     7201 atcaattttt agtctttctt ttcaatatac caaggattga gatacacact atacctaaaa
     7261 caggtaaaaa gtcttctcca actccagtaa caggtaaaat ttcttgattt cgtacagaaa
     7321 cagcacctct cgaatttcga ttattagcca ttttttgatt aatattataa tcaactgaaa
     7381 ttacttcttt tgaaatgtta tgaaaatcat ttttgataga aaaattgtta tttgtatttc
     7441 tttgaatttc tttatcttgt tcctgtttca ttctatccct tctaaggtag gactctttaa
     7501 gatttttcat tgatttatga ttaatagaat cattctgacc tttagccgta tctaagctaa
     7561 aagctttatt tttcccattc aataaatcaa caatattcag cactctattc ccattaactt
     7621 ctggagaatt cattaaaaga aaccttttta gttggttagg attctttatt ccatatttat
     7681 caactactaa tgccagtgcc ccagatactt taggaacagc aaatgagttg ccataaacat
     7741 attggtacca gccagtatta gtagttgtaa aaagccaatc tttcaaataa taaccctgac
     7801 tgacaaattt atcttgccca tattttttaa aattggccgt tgtaccagca ggagcataaa
     7861 ttgcatccac cccaatatta ctaaaatcag aaatattacc ataaccatct attccaccta
     7921 ctgctattac atcctcaaat acactcggtg catctacaac ttttccagga acctttatac
     7981 ttctgaaacg cttaagaaag tttatcattg tttagttatc ttgtatgttt aaactatcat
     8041 taccaagggc tgcgacaact atacttcctt ttgttgttgc ataatttact gctgacttat
     8101 aattaagata ctcctgataa tcatttgttc catcatcata cgatcctgaa atcataagat
     8161 actgtccagc acttatattg atgaccttgt tcccatcatc cgcagctctt cttattgctc
     8221 tagctaccca ttccgatttc gaaagatttt caccaaatac tctgtatata tttacagtaa
     8281 tccctggtgc tactcctaaa atgttcccat ttgttgtaat ctgacctgcg acttccgtcc
     8341 cgtatcccat tttgtccaca atatcacttg gatttccagt ttcatcaggt tcttcattat
     8401 caaaccctcc cttaggaacg agatttttga aataatttcc taaactattt gacaaatcag
     8461 gatgttcttc catgattcct gaatcaataa ttccaacaga aattttcttt gagggctggt
     8521 agagcacgta gctttctcca ttatttgtca catatttcat atcccactga taatcccaaa
     8581 aatcaggtaa atttgtataa acacttgctt tcttttcaga agaattgttt gtcaatagag
     8641 gttgtgtttc tactttttaa ttttttaaat gttgtctaag aggtacccct tccttagctt
     8701 taaaataata cagaggagaa gtagaattat cagttacacc agatgcatct ttagaatttg
     8761 atagtttttc cttaataagc tgagaggaag taacaaagtt agctctattt ttctcattct
     8821 tgatgatttt atttttttga atcgatgatg ttgaagcggc tacttcactt tgctcaagta
     8881 gctcatcctt agatactgga accgcttctt tatttgtaat gctatctctc ttgcttaatt
     8941 cagaactaac ttgagtttct tccaacgaaa cttttgtttc tttttgagca gctgatgtct
     9001 gtaataaaat tttatcagca ccagttttac ttacatccaa ttcagtcctt gtagtcgatt
     9061 ttactgcagg tgactgctcc cctagattaa tcgaatcagt cgttgatccc tctgttgaag
     9121 ataaaattgc attagaattg tgattaatta attccgtatt aatattattt gagggtaact
     9181 gttgtgaatt tgttgtctcc tcatgtacag ttgctgataa acccaacgaa ccaacgataa
     9241 aaaggaaacc taatattttt ttcactctag tttcctacct tcgttgcaag cttaaaatca
     9301 tcatttatct caacggcaaa cgcttcagta agagattttc ctctaataga atggatttcg
     9361 ccataatccc attccgtcct actctgtttg gaatttgaac catccttatc aattctcccc
     9421 cattcagacc taggaatact tttgccacta actgaatcaa acacacgtac ttcagctaaa
     9481 atatcctgat attctcccaa ttcttcatca gatacggtgg tgtccgatat actgtaaata
     9541 tttcccatat agtcaatttt tcgtgaatca tttttatcaa taacaaaatt atcatcagaa
     9601 atatcgcttg tcacatcaaa attttgtaat ctcaaagctt tgacctcccc cttctcactt
     9661 tttggaagta tcttatagta tctgtcgtta atacccatac atagcgactt gtcagaagct
     9721 tcataaatat tatttaagac caaagtcaca ctatttttgt tgctacttga taaaattttc
     9781 tcacttttca tgtcaacaat caacagctta taaaattttg ctttggaatt gttaacgttc
     9841 tcctgaggaa tctccttatc ggttacgaaa tacgatttat tatcataaat aaaattatta
     9901 taacttcctt cgtcaaacct tacctttttt agacttgttt gatagcatcc tgttaaacct
     9961 gttatcccta gtagggtcac aataagtatt aaatattttc tcatttccac ttccctcctt
    10021 taaaaaaatc gtcaaaaagt aacagtgctt gtctccaata agtaatattg attgaatatt
    10081 caaatttcga tattaccaat atacagccac ttatgccttc aagaaaaccc atgccactct
    10141 catccccgta ttctttaaga atttgctcac tattgacatt aaattcttct atgtatgaat
    10201 caaacttttt tgtatttaat agccgcttaa ataaagaaca aatttctatt aaaccagaat
    10261 atccatggca aatcatatat gaattaatac caagttttct ttgcatagct gactctaata
    10321 ttttttctgc tttgtctaca aaatagtcat tatccaaagc taatcctccg tataaatata
    10381 gtagactaat acctggacct ccatagcacc atgcatctct aatgaaacat gcttccctaa
    10441 tcactttctc tttttttaat tcatctacta caagcccatc tttccatagg aacttatttt
    10501 tcctttcaag ttcaaacttt tcataaataa aaataatgtt tcgcaaagct gacaacgatg
    10561 ctacattact atatcctttt ttgtgggcat aagctaagat actgcccatt ccagcaagtc
    10621 catgtgcgaa tcccatattc aaacagccta atggatacat ctcactttct gattgagaca
    10681 tctgattctc cgatttgatg taaagcgata tgagtccttt gttttcttta gtcagatttg
    10741 ataaaaaatt gataatgagc attttcaaat catcatattg ctcgtcgttg attaacaata
    10801 gataggaaag aattccagat aaaccttcaa tcacgtcata atcaggagga gtaatgtaga
    10861 atcaaataat tctgttatct gtacttcttg atctacacca tatttttcga taaatttatc
    10921 tctatagtca tccaaatatg ttcttcttac agattttgtc gtatttccta aaaactcagc
    10981 taaatgttct aattgttgct tctgtttgac atcaaaattg atttcactat cactaatcaa
    11041 atcaatttga acatagttat cattcttaag aatttttgac atttcctgat atatttcttt
    11101 gagtttctca ataccttcac caatttctat ttctgagtat tcttgaataa acttttgaat
    11161 ttttttcaga gtaattatat attttttatc atcatctatt gcttcaactt taatcaaaaa
    11221 agtatcccaa gaaaagtctg ataacaaatc tttttgtaaa ttggaaatca aataatgatt
    11281 aactatgaga ctgtcaagat actgttccga tagttctctg tatttttctc cataacatac
    11341 cgttacggtt tcacaaatat cttcatatct ttgataagca ttttcacaaa atttagaaat
    11401 catttggtaa acattcgtat atttaatatt tacttcttca agctcactac tattaatagt
    11461 ataaacttga aaaactcgat ctccaaactc ataatttgca ttatttctaa taaatgataa
    11521 tttttttgag aaatctattt ccatttgatg aaccaggcga atcaaccact gagtatccaa
    11581 gcttatactc tttgtagtct ttcccgttaa gtcatactgt gagctttccg aaaaaacacc
    11641 aattgaagtc tcactaaata atccgattgg cgttgaacgt aaataacttc tcttataata
    11701 cttgtagata gactcaaata attttttagc ccttttcttc tttaacaaac ctgcattata
    11761 tttctgcata acatcgtaga gtttaggatt agctagtagt aactgttcca aaaaaacttt
    11821 atttttactt acagtctcaa tgacttgagt atattcagta aaactccgtt tatcgttagg
    11881 agatagtatt gtatttctta ctaaaaactg ttgagcttta aatgaacttt ttatcatgtt
    11941 ttttcctctc tttattttta taagctattt agcaacccta aataacttat aaaaatagga
    12001 tagtatccat gtctgaacta acaaaatact atcctttgat ttggttattt ggttatttgg
    12061 ttatttggtt atttgcttac gtgaatacta caattacaag ttgctgtttt catgttacaa
    12121 cccatcagag ctcctgtttt acaaccgggt gtacatagcg aaatacttgt aatgcgtggt
    12181 gatacacctg aatctttctt tgaaacagat atcaaatcca agttaaaatc ttttgtactc
    12241 gtttcgagtg cctccttata atttattatc tagttccttc gaacgaaact attgtatcta
    12301 acaaacttca gaatttattc agagccattt attattcccg cattatcgac aataatatta
    12361 ttgccaatac tttctcaata tagaattaaa actgttttag atttgttgat gtttctattg
    12421 ccagtgtagt tataaaacta ggtcattcaa gtatgtctaa ggctcaagaa acctatctcc
    12481 atgttattta ggaactagag aatcaagata atgataaaat tattagatat ttgtaaactt
    12541 tagcttaaat aaatattttt ttaaagagat tgttttaatg attttaactt gtcaagttta
    12601 gactaatgaa gagtgatggt attcatcgag gtgtctaaag aataatccaa ctttctgttg
    12661 ttcctcataa tttggaacat tcagaactca atcatttaca attgctcacg ataggttcac
    12721 ttgtcctccc tgtaaatatt tgtttgtttt tgtcgtttta aagattggat aatagcaaga
    12781 atcaccaaag tagtaaatgc tatcatgaga cccaatgact gaaatacatt caaaaattct
    12841 cccctttaat gttttgtgag gtcttgaaca gtaaaatact tgctgaagga ggcatctttt
    12901 ttcacttaaa agatgaaagg tttcattttc ttaaagtcaa cattaagtta taaaccttta
    12961 cttgtcatgt ggtcaacttg ccatttttct actgttgata atcaaaatat tgctttacta
    13021 cgtcgatttt tttcatagca ctctactact tcatcaacag ttagtgaaat ttcattcgtt
    13081 tttatccgtt caatgataga ctctaaatta tagttatctg aatgtttctt atcaagattt
    13141 cgtccacgtt tttttatttg tggctcatca agcaacagat aagtggccca ctttccataa
    13201 aaatcaaaag ataaatttat ttttctgaaa cagttagctt tttctcacta cattagtaac
    13261 atttttagat acaatattaa gattgataac tgaatctaat actgacccta aaacaacacc
    13321 tcatatggtg tttttttctg aaaatatata tttttattta acatccttct tcgataataa
    13381 gcgtaaagcg tttaatgtaa caaatattgc cattcctgta tcgcttaata ctgttaacca
    13441 aataggtaat actccaccaa atacggatat tctaaataat atatcccccc ttacagaaca
    13501 tttatattgt catcatcaaa catatctatg gaatggcctt agataaccaa taccaggttg
    13561 tataatctaa caacagaaat caagtacaag taggaaacac ttaaacatgc tggacagact
    13621 ttccataatc atcaataatt atatttgaat taaatttttt ctcaattgat tatgtgactt
    13681 tgattataga aaattttttc ttatggctca tttattttta tgtatattat ttcagtttat
    13741 ttacttgcaa attgaataac catattaaag agaagggcac ctaagctacc gccaatgatt
    13801 ggacctaaaa caggtatcca tgcgtaagac cagtctgaat ctcctttacc tttgataggt
    13861 aagatggcat gcatgatgcg aggacctaag tcacgtgcgg gatttagaga gtaacctgtc
    13921 gttgcaccaa gtgataaacc aatggctgtg ataatggcac ctactaaaag gggtgagaca
    13981 cccgaagttt gcgtaatagt gtattgaccg aaggcgagaa ttcctgtcgt caatactgca
    14041 gtaccaacaa tttcactaat caaattcgag cctgtatgac gaagagcagg gcctgtagaa
    14101 aacgtgccca agatatctgc tggatttttt gtttcagcat agtgagggta aaacattagg
    14161 tagaggataa tgctggcgac cattgcacca agcatttgcg caataatata aggaagaacc
    14221 aaactccagc taaagctccc aatcattgcc attgcaattg ttactgctgg attcaaatgg
    14281 gctggcgaca taaatccaga aatgtaaacc cccatcatta ctgcaaatcc ccaaccgaga
    14341 gtgatagcaa cccaaccagc tcctgttgct ttcgttttgt tcaggacaac gcctgaaacg
    14401 accccgttac caagaagtat taagataaat gttcctaaaa attcaccaag tagctgtacc
    14461 atttctgagt gcatattgac cccttatttc tattttttat ttgtttcaat tatcttcaaa
    14521 ctatttttat ttcttcaaat ctgataagtc agattcacga agcgcttttt ccaaagcttt
    14581 ttcttgttct gctttttctt ctacagacca accgagaaag cctgcaatga cgttgacaac
    14641 atgaactttg attgtatcta cactttctcg cataaataaa atatggttag tacgacgaag
    14701 gaagtagtct accggtgtca agatcatttc atcctcaagc gcataacgca gacgggctga
    14761 ttctgccaaa gataagcctt cataaggttt catttcagaa gcataggcaa atacttggag
    14821 cgcgttcatt ccataaaagt ctgctatgta tttcgcctcc tcttctgtaa gacctgcaac
    14881 aacaccgatt ttcatatttt cagcaacgac ttcttcaacc ttagttggat caaattcacc
    14941 accagagatc tggtattttt tagagtcgat tggttcatat ttcaaatcaa agtcctcaac
    15001 aagcagctgg cagataagct ccatcgcacc tgctgccatt ttacggtagt cagtgatttt
    15061 cccaccagct aaagtaatca aaccatcact ctcacgttca agtgaactcc cacgagaaac
    15121 tgaagatggc gcgtcccctt tttctgaaag acttgattcc atattgttca ataaatgctc
    15181 tacttcggct ttagttgctg ttttattttt atagcgaagc acggcctcta cgacagcgtt
    15241 aaagctagtt tcagaaactg caccgttatc acctccgtta tagtctgaac ccgaattccc
    15301 acctagcaat ggacgcaatc cagcccatga agcttcaatg tcattaatcg tgatatttgc
    15361 tccaggataa cggaaattga tgacatctaa aaggtagtcc acatcttctt gagtaacctt
    15421 tggatcggta aagtccccat gataatccgt atctgtcgta ccaaaatatg ttttattttc
    15481 acgtggaatg gcaaaaacca tacgtttatc atgttttcct gtatcaaaat atgttggttg
    15541 aggcacaggt aatttggcag catcaaccac aagatggaca ccttttgtcg gacgcatttt
    15601 tggcacaatc ggacgagtga agttcaagta acgtatctta tctacccaag gaccacttgt
    15661 gttaatcaca agtttagatt ttacttcaat gacttcatct gtcaataagt cacgcgcccg
    15721 aacaccagag atttgcccat cagtatagat aaaatcaatc actttcatct tgctgatggc
    15781 ttttgcgccg tcttctacag cttttttaat attgtcaatc accaaacgtg aatcgttgtt
    15841 acggtagtca agataaaccc ctgcaccttg caaacccttt ttcttgatca gtggctcacg
    15901 gcgtagcact tcttctggtg agatggtata gttggcatat ggagaacctt catcaatacc
    15961 tgccaaccga tcatacaaat ccatggcgat tttcacagaa aacatatcaa aagtcgtttt
    16021 gccttcatca ttgtaaatag gaagtaacat cgggtctggc ttaggaatat gtggcgcaat
    16081 actttgaaca acagcacgtt ctgaaacagt gtcggaaacg acttcgacat caaagttttt
    16141 tagataacgg atacccccat gcacgagttt cgttgaacgt gacgatgttc cttctgaaaa
    16201 gtcctgcatt tcaagcacag aaactttcat accagtggct gccgcttgta aagccaatcc
    16261 agcaccagta ataccacctc cgataatgag taaatccatt tcttcattct gaacttttgt
    16321 gattgcttct tgtcttgttt ttttagaaaa agccatttct attctccttt atgttactgt
    16381 ctgattgatt attatttgaa agcgcgtgtt gcattcacag cttttttcca accggcatag
    16441 agttcttctc tacgttcttt ttgcatctgc gtttggaaaa ttttgccagg ctcataagat
    16501 tctttgagtt cttctaaatc tttccaaaaa ccaactgcaa gacctgctag gaaggctgca
    16561 ccgagtgctg tcgtttccaa atctcccgca cgttgaatag ggatattcaa gatatcggct
    16621 tggaactgca tcaagtattc gttatttgct gcgccaccat ctactttgag tacagacata
    16681 tcgattcctg tatcttcttt catggtgctg actacatcac ggacttgata agctatccct
    16741 tgtaaggttg ctttcacaat atcttctttt gttgttccac gtgttaatcc aaacattgcc
    16801 ccacgcgctt cttggtccca atatggtgcg ccaaggccga caaaagctgg aaccacataa
    16861 acttcatctt gactcataga ctggagtgca acttcttcag aatcactggc acgatccaac
    16921 atcttcaaac catcacgtaa ccattggatt gatgaacctg caacaaagat acttccttct
    16981 aaggcataat aaacttttcc attaataccg tagccaattg ttgtgagcat gttatttttg
    17041 gaaatatgtg gtttttcacc cgtattcatc acgataaatg aacctgtacc ataagtattt
    17101 ttaatcatgc ctggttcaaa ggccatttga ccaaataatg cggcttgctg gtcaccagcc
    17161 atacctgaga ttggtacttc agatccgaag aaatgaaatc ctttagtcac accataaact
    17221 tctgagtttg atttaacctc tggaagcatt gaagccggga tattcagaat tttcaggatt
    17281 tcttcatccc atttcaactc gtgaatgttg tagagcatag tacgactggc attagagtag
    17341 tctgtataat gtacatcgcc atctgtcaac ttccataaaa gccatgtatc aattgttcca
    17401 aagagcagct cgcctcgttc cgcccgctct tgtgctcctt caacatggtc aagaatccaa
    17461 cgaatttttg tagctgaaaa gtatgagtcg acaatgagtc ctgtcttttt gtggaagagt
    17521 tcatcatgcc ctgcatcttt aagaccattt gcaatattgg aagattgacg tgattgccaa
    17581 acgatggcat ggtagattgg tatacctgtt tttttatccc agataatggt tgtttcacgt
    17641 tggttagtaa taccaatacc agcaacctgc acaggcttaa taccagattc gataaatgct
    17701 cctgcgataa cagattgaac agagttccaa atttcgttgg catcatgttc cacccaacct
    17761 tctttaggaa agtactgtgt aaattccttt tgggagctgc cgatatgttt accatgttta
    17821 tcaaatataa tagctcttga gcttgttgta ccttggtcaa ttgccataat gtaagaagtt
    17881 tctgtcatgt tgtttctcct ttgtaaacgc tttctataat ttatattata gcattttaaa
    17941 acgaatagaa actttcattt tttatcaaat gcaaaaaaaa attggcagtc gaaaataaac
    18001 aacagattcg aatagaaaaa ttacttgaat ttgggcagtt tgtgcttact aagaaataat
    18061 gagagaggga gtctctaccc caatttaatt ttaaccttat ttgagttgct attcttaatt
    18121 cttcttctat tacgtaataa attcagtgaa aaaatgctaa ataatgggac cgtagtaata
    18181 tctccataaa tgtaaaataa tattcacgtg aaaacataaa aaaagaggag agcacccctc
    18241 tttcgtgttt tatttttaat tcaaaattgc ttttttttga aatttttctt tttttaagtt
    18301 ttcaatacgc gacaataact cttcaaaatc ataatcactg gaaaactcgg aaagtatata
    18361 gacaaacttt cgactgtcat ttcttttact tgagataagt agatcataac tctggctttc
    18421 ttggtaatgc tctaatttta tcttttcaac aggtctgagg tgatttttca gatagtgttc
    18481 catcgggatt tgataggcag gtgtatcaga caaatcataa gccaccgtca attgttgagc
    18541 agataagagc tccagcagca tcaaggcatt gcgataacca aagatgagtt ctggtaaatc
    18601 ctgctctttg ggtatataac ttaaagcaat atctttgagg ttatcgagta aatcttgaaa
    18661 actcttatcg acccagtttt gtttatgtag catcaaatct tcttgaattt tggtaaagag
    18721 actaccttgg aaaaaggtga atttattgtt tacttgagct aactgataac tgatggattt
    18781 ctcctcttcg aaacctaaac gatggggacg atagtggttt aacattcgct ctcttagaga
    18841 aatattcaag agaacagttg gaattttttt actgcggtaa atatcaaaac ggtaataact
    18901 ttctttatct agaatgaaaa aagattggag aaaactgtag aaaaaaattg tctcacagtt
    18961 atccttgctc tgattatcat aaatatgttg ataaaaaaga gagtccaata gttgatagag
    19021 atgatcatct tggtatatta tcttcatttc taaagattta gtaatttgga tatctgtaag
    19081 tttccgcctt ctttctgtga ttgccaacca ccgataaagt ttatctttgc tactttcgga
    19141 aaaatttact tttaatgttt cttcaagttg ccgtacaaat tcaacctgaa atttagtgac
    19201 ttgcagcaaa tctggtcgaa atttaggatg aagtgaatca aatagcaaat agtaaaaata
    19261 gcgaatttga ctttcttctc cgatcaattt attatttttg atttgaatat caaattccaa
    19321 taaaagttta ttgagttctt tgattttgcg aaacaaagta gattcactga gtagcaagag
    19381 ttctgctaat tcaaaaatca tgtaattttt ttgttctaaa aataagagaa tcaggcgata
    19441 tttgatacta tcttggatta aaaaactgat gacttcatct aaggtttgtg attccggcat
    19501 gtttagaacg agtttattgt tctgacgaat aacttccatg ggtttcccaa gcatccgtcc
    19561 tatataagat atatcctcca aataactctg aaccgaaggt cgagagaggt ttacccaatc
    19621 acacagttcc tgcgcagtta gcttatcatg tttgaggaac aactgacgta aaatcttaac
    19681 ctgtatttgt tctttctttt caagtaaaac ttcaatattc acagctgttc ctctttttct
    19741 aaattaatat tttttgtagg agttttcata ttctcattct attttatcac tcccctatat
    19801 tttgttatta aaaattgctc agtatgaaca tagtaaattg gacactaaaa agaatatgac
    19861 caaaagcctt attcttcttt taaacttcta tattttgcga ctaaactata aaagtgatta
    19921 gataaactta gattataatc tgtttatcaa acactaaaca tgttttatat taattcacga
    19981 taatatataa actaatataa ccaaatccct tttagtaaat ataccaatga atcaataaaa
    20041 aaataaatac caatacctaa tataaataat gatattatta ttctagtgac attacttaat
    20101 ttttttcttc ggttattttt atctaaatac ctacttgcta ttttaatcaa tttttcatag
    20161 acattaaata ttaatgatac tactaaagta tataaaggaa tctgtcctaa caacatccaa
    20221 attgttaaac ataatattgt taatagtata ttcccctctt ttgcacttag tgcaaccact
    20281 gcccaaaaag tcggatctga catagcccaa aacccaaaaa taaaacctgc aagtggcata
    20341 cttctctttg caaatttcat aaatttcgct tctttctgat catctactct ttctttattt
    20401 ccttttagta aggtagatct tataaaccaa gctacacata caatggatat caaaaaaccg
    20461 gtaaatacat aagccatatc tggaatatga ttcattatat ttataaaata attcaagctt
    20521 atactagtac cgtatgaaaa tattaatccg aaaacgaccg tggaaagtag agccattaaa
    20581 gaaaataaat atacttgttt tttctttgtt ccatttgcta gtgcagccat tataagcact
    20641 gctcccactg gatcaaatcc accgaatcct aacaaaattg atgatagtat taatttcatc
    20701 tatcattacc tccatgtatc aatttctcta gcaacaatct tttaaatttt tgtaaattca
    20761 ttaggcatcc attacttgtt ttagaatatc gttataaaga acagactgat tttattatta
    20821 tcaatgaaat aataaagaca ctccaacatc ataagctctt gtccaacaca ggcatattct
    20881 agcaaataga attgataatt accagtaatc aactgagttc taataaagag ggtaatgatc
    20941 ctacgactgt ttgatggaac ataatcgttt atcgttgcta tgaaccatgc gaatcaactt
    21001 tattggtaat atatttagtt acttacttta gaaaaagcct caataggctt tttattgttt
    21061 ctgtaattgt aaaacttgag cattatttat ctctttaaaa agtttattac ttgtttcttt
    21121 agaaattaca tcagttttta cctggttcaa tacaaattga tattcaagtt gaaaagcctc
    21181 tatgagtaat tcgtttggaa taattgtatc ttcttgaatt tcgttacgaa tacggtaatg
    21241 tctattttcc aaaatatgtt ttacttcttc aatatcacta aagtcagtta tcttattttc
    21301 taatcgctct ttttcaagag aacttaattt ttcgattgtt tgttgatata aactgctttc
    21361 tagtcggctt atatcagttc ttattgtcgc aaattcttgc atttctactg aatctactct
    21421 tctgccacgt cgtcttttgg agaataatcg tcttattttc ttactagttg aatgtttact
    21481 actgttttct agataaattc taaaatagtc aataacttta gatgaaaatt gtgcttttat
    21541 agttgttgta tcaagtaatg tttcctgcca acttattatc tcgtccatta atttactact
    21601 cttagtgtgg tcaggaattt gtaatccttt ttgtgattgt agttgtttgg taagactact
    21661 acgaacttta ctatcctcaa tttcttctac catatgaaga atcgcataat caaccatatc
    21721 gttacgaacc tgatttatat tatcagtact ttcacctcca agtgccggta ataattttgg
    21781 cagaatcagt gttggtacaa taagacttaa aagaataaca atagcggcca ttgtaataat
    21841 aatttcccta ttctcgttgc tcaaaatact agtattcaaa ggtaaagaga aagccattgc
    21901 taatgtcatt gttccatggg ctcctgacaa agcaaaa
//
