LOCUS       NC_013656              20252 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Lactococcus lactis subsp. lactis KF147, complete sequence.
ACCESSION   NC_013656
VERSION     NC_013656.1
KEYWORDS    RefSeq.
SOURCE      Lactococcus lactis subsp. lactis KF147
  ORGANISM  Lactococcus lactis subsp. lactis KF147
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B., Wels,M., van Hijum,S.A.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Complete genome sequence of Lactococcus lactis subsp. lactis KF147,
            a plant-associated lactic acid bacterium
  JOURNAL   J Bacteriol 192 (10), 2649-2650 (2010)
   PUBMED   20348266
REFERENCE   2  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Starrenburg,M.J., Boekhorst,J., Renckens,B.,
            Molenaar,D. and van Hylckama Vlieg,J.E.
  TITLE     Genome-scale genotype-phenotype matching of two Lactococcus lactis
            isolates from plants identifies mechanisms of adaptation to the
            plant niche
  JOURNAL   Appl Environ Microbiol 74 (2), 424-436 (2008)
   PUBMED   18039825
REFERENCE   3  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Complete genome sequence of Lactococcus lactis ssp lactis KF147
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 2598144)
  AUTHORS   Siezen,R.J., Bayjanov,J., Renckens,B.A.M., Wels,M., van
            Hijum,S.A.F.T., Molenaar,D. and van Hylckama Vlieg,J.E.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-DEC-2009) NIZO Food Research, Kluyver Centre for
            Genomics of Industrial Fermentation, PO Box 20, Ede 6710 BA, The
            Netherlands
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000025045.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 01:08:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,639
            CDSs (total)                      :: 2,548
            Genes (coding)                    :: 2,493
            CDSs (with protein)               :: 2,493
            Genes (RNA)                       :: 91
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 25 of 55
            Pseudo Genes (incomplete)         :: 23 of 55
            Pseudo Genes (internal stop)      :: 14 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:59:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 90438
            Orig. end                         :: 110690
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001834.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria source: Dr. W.J. Kelly, Agresearch Limited, New Zealand;
            william.kelly@agresearch.co.nz.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20252
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20252
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20252
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10252](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10252
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(351..364)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    389..407
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.14"
                     /tool="antismash"
     gene            1868..2176
                     /locus_tag="LLKF_RS00460"
                     /old_locus_tag="LLKF_0086"
     CDS             1868..2176
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012896957.1"
                     /locus_tag="LLKF_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0086"
                     /product="hypothetical protein"
                     /protein_id="WP_012896957.1"
                     /transl_table=11
                     /translation="MTKLNFFDYWLVGEEGYSLILILILPSQININFWLVLTSKQTSGS
                     VFNIIALPILMALPNLIQRVMTSNSIYWTKQKYIILILNCILLSVTTFWLLTLPFGQ"
     gene            complement(2218..2517)
                     /locus_tag="LLKF_RS00465"
                     /old_locus_tag="LLKF_0087"
     CDS             complement(2218..2517)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011675168.1"
                     /locus_tag="LLKF_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0087"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_010905131.1"
                     /transl_table=11
                     /translation="MMNMQSMMKQAQKLQKQMQVSQEEIANTTFVGKSAQDLVTVEFSG
                     DRTLKSLDIKPDVIDPEDPETLQDMVTDAVNDALSQIEKVTEQKLGKFTKGLPF"
     misc_feature    complement(2709..2729)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.95"
                     /tool="antismash"
     tRNA            complement(2736..2821)
                     /anticodon=(pos:complement(93223..93225),aa:Leu,seq:aag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LLKF_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Leu"
     gene            complement(2736..2821)
                     /locus_tag="LLKF_RS00470"
     gene            complement(2906..3841)
                     /locus_tag="LLKF_RS00475"
                     /old_locus_tag="LLKF_0088"
     CDS             complement(2906..3841)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (89-208). E-value: 2e-13.
                     Score: 42.4. Matches aSDomain:
                     nrpspksdomains_LLKF_RS00475_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017863974.1"
                     /locus_tag="LLKF_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0088"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_012896958.1"
                     /sec_met_domain="PF00561 (E-value: 5.5e-10, bitscore: 36.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.2e-09, bitscore:
                     34.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFRKKQIWRVIIGLFALLLVINLGATLYFYQIACVRNNQQIGQ
                     VKSSSPNYSLVQKFDKLSKSTESIKNDGLKLDAWYVPAEHKTNNTVIVVHGFRQDKSAM
                     RQYGQLFHELGYNVLMPDNRGAGQSEGKFITFGYHDKFDIIAWANYLTDKNPESQISLY
                     GLSMGASTVMMASSEKSLPSSVKNIIEDCGYTNAWDEITYQAKESYNIPPFPLVYSVSL
                     ESKLRQGWFFQEASATKALTKDKLPILLIHGSNDTYVPTSMVYENYKAVKKGTPKELLV
                     IKGAAHAKSFETNPELYRQTISKFMKAYNP"
     aSDomain        complement(3218..3574)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LLKF_RS00475_Abhydrolase_1.1"
                     /evalue="2.00E-13"
                     /label="LLKF_RS00475_Abhydrolase_1.1"
                     /locus_tag="LLKF_RS00475"
                     /protein_end="208"
                     /protein_start="89"
                     /score="42.4"
                     /tool="antismash"
                     /translation="TVIVVHGFRQDKSAMRQYGQLFHELGYNVLMPDNRGAGQSEGKFI
                     TFGYHDKFDIIAWANYLTDKNPESQISLYGLSMGASTVMMASSEKSLPSSVKNIIEDCG
                     YTNAWDEITYQAKES"
     gene            4083..4403
                     /locus_tag="LLKF_RS00480"
                     /old_locus_tag="LLKF_0089"
     CDS             4083..4403
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011675173.1"
                     /locus_tag="LLKF_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0089"
                     /product="SugE family quaternary ammonium compound efflux
                     SMR transporter"
                     /protein_id="WP_021723289.1"
                     /transl_table=11
                     /translation="MTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGF
                     LALALKKLPLGIAYPIWTGIGAVGSILIGLILFKDKVPPLTWLFIACLVVGIIGIKVTS
                     GH"
     gene            4525..5688
                     /locus_tag="LLKF_RS00485"
                     /old_locus_tag="LLKF_0090"
     CDS             4525..5688
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132321.1"
                     /locus_tag="LLKF_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0090"
                     /product="MFS transporter"
                     /protein_id="WP_012896959.1"
                     /transl_table=11
                     /translation="MKNKKSMMNLAISNLFLVFLGAGLVIPVLPTLKEQMHFSGTTMGM
                     MISIFAIAQLVASPVAGALSDKIGRKKLIAIGMIIFSFSELLFGLAQAKTGFYISRALG
                     GVAAAMLMPSVTAYVADMTTIAERPKAMGLVSAAISGGFIIGPGVGGFIAHFGIRVPFY
                     VAAILAFLGFILTITILREPERTIESHQEIEKVSFLDILKNPLFGSLFIIILISSFGLQ
                     AFESIYSIMASINFGFSMSEIALVITVSGILALFFQLFLFDAIVNKIGELGLIQLTFFA
                     SAIFIAVIAFTKSNLVVALSTFVVFLAFDLFRPAVTTYLSKHAGNRQGVINGLNSAFTS
                     FGNILGPMAAGYMFDLNHLFPYYISAIILLGTGFLSLFLNRKNFSKI"
     misc_feature    complement(6046..6061)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.58"
                     /tool="antismash"
     gene            6585..7388
                     /locus_tag="LLKF_RS13095"
                     /old_locus_tag="LLKF_0092"
     CDS             6585..7388
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /locus_tag="LLKF_RS13095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0092"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_012896961.1"
                     /sec_met_domain="Abi (E-value: 2.1e-08, bitscore: 31.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYGTVICSIFYYIESIGGLKIQPLFFKKQFIAILLIILSLIFLV
                     GYDSISLLSIYYLLFVLSLTLFPYLKFKLSYSYNLQVILLGIVLYFPIFNINMNEWIGN
                     FTISQFLISAIFLLVLLYTIHWKELMQHYNTLNSYIKLTLPGMVGSLFEFFYYIIGEEI
                     FYRFFIIGYLSKSINILLCVFIGSILFVYSHYLNRWANIIFTNKSYISLFLLGVFLSLV
                     FYQTHSLLLCIILHIIYNHSELIVIYKRFKVKNIDEKSDVFDDYD"
     gene            7400..8200
                     /locus_tag="LLKF_RS00500"
                     /old_locus_tag="LLKF_0093"
     CDS             7400..8200
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773072.1"
                     /locus_tag="LLKF_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0093"
                     /product="ABC transporter permease"
                     /protein_id="WP_012896962.1"
                     /transl_table=11
                     /translation="MLQTILATYKKNRRTQLRAYPISFMFQRVLGSLMGLLLPVLLYYF
                     VFNQNLSSSFLSQTNHMSYIMYVGLGYCSYGLSIATLMNVGRAIILEIREGTLDNFLLS
                     PASRLGYFIGVYLEQWGRAFIEFIIIFSFSIILGMPFSIANLVRILFALLILSVVSLCM
                     AVLLSTVMVFTRDTFITQNTLFIIITVVAGVAFPVSYLPSVVQIISYLMPLTPAITIVR
                     LLISYQSIPLMLWLIMIVESIIYFYIGYFWFRRVEKKLIEEVLS"
     gene            8209..9180
                     /locus_tag="LLKF_RS00505"
                     /old_locus_tag="LLKF_0094"
     CDS             8209..9180
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773073.1"
                     /locus_tag="LLKF_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0094"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_148210852.1"
                     /transl_table=11
                     /translation="MRDISKSFVIKEKRNGIFKRSNKVEKTVISDLNLKIPKGKIVGLL
                     GMNGAGKTTTIKMLSTLLLPTSGYIYLDGKNILENQNEIKNKVNLISGGEKNLFWRLTG
                     RENLEYFASLYGIDRKKTKQIIKEILEIVKLESAADVVVEKYSKGMKQRLQIAKGLINN
                     PDYLFLDEPTLGLDVLIAKELREYILKLAKIENKGILLTSHYLHEVEELCDYIYILEEE
                     QVKNEGTASQIISKLNKVIKTQIRFEQRIPELYDSILSFITVNNVNWIEEGTLEIISSE
                     EIVPNILEIIGISNFKKIISITSIKPTLEDCLISEWEEKLEL"
     gene            9170..9979
                     /locus_tag="LLKF_RS00510"
                     /old_locus_tag="LLKF_0095"
     CDS             9170..9979
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773074.1"
                     /locus_tag="LLKF_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0095"
                     /product="ABC transporter permease"
                     /protein_id="WP_012896964.1"
                     /transl_table=11
                     /translation="MSFKSNLIALRGEIIKQNRNYHNSLSSILSLLIWPIMNLIYIFFL
                     YKSFNISYLSRYGITTINEFIIFLITGALVYNCFWSMVQSAFYLSFERQNGTLESVFIT
                     PVNILSYLYGRALGGIITSLWMYFSFSFIILFLTREFSIRLVMVSIIAVVIVVFSATVW
                     GGFINAIFLSSRDASYLFTICDEPMRIFSGSTVPILAFPIWGQIISYIFPATYCLYIVR
                     NIYMSTLFNLNMYIYFILSLLILVALTFIIAKVSYKNSQKNGSLQLY"
     gene            10001..10252
                     /locus_tag="LLKF_RS00515"
                     /old_locus_tag="LLKF_0096"
     CDS             10001..10252
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="LLKF_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0096"
                     /product="PqqD family protein"
                     /protein_id="WP_012896965.1"
                     /sec_met_domain="PqqD_RRE (E-value: 6.9e-10, bitscore:
                     35.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-14, bitscore: 51.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 2e-09,
                     bitscore: 34.6, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-08,
                     bitscore: 32.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKSYKSQLVKFQGKFMITDTKIVFEVNEIGARIYDLCNGKNSV
                     EDIANKLSNKYKIGYDEALKDINDYLSELEELQLIVKE"
     aSDomain        10016..10240
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LLKF_RS00515_PqqD_RRE.1"
                     /evalue="7.70E-12"
                     /identifier="RREFam006.1"
                     /label="LLKF_RS00515"
                     /locus_tag="LLKF_RS00515"
                     /protein_end="80"
                     /protein_start="5"
                     /score="35.8"
                     /tool="antismash"
                     /translation="YKSQLVKFQGKFMITDTKIVFEVNEIGARIYDLCNGKNSVEDIAN
                     KLSNKYKIGYDEALKDINDYLSELEELQLI"
     aSDomain        10064..10228
                     /aSDomain="Thurincin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a thurincin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LLKF_RS00515_Thurincin_rSAM_RRE.1"
                     /evalue="2.20E-11"
                     /identifier="RREFam019.1"
                     /label="LLKF_RS00515"
                     /locus_tag="LLKF_RS00515"
                     /protein_end="76"
                     /protein_start="21"
                     /score="34.6"
                     /tool="antismash"
                     /translation="TKIVFEVNEIGARIYDLCNGKNSVEDIANKLSNKYKIGYDEALKD
                     INDYLSELEE"
     aSDomain        10076..10246
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LLKF_RS00515_Stand_Alone_Lasso_RRE.1"
                     /evalue="1.20E-10"
                     /identifier="RREFam002.1"
                     /label="LLKF_RS00515"
                     /locus_tag="LLKF_RS00515"
                     /protein_end="82"
                     /protein_start="25"
                     /score="32.2"
                     /tool="antismash"
                     /translation="FEVNEIGARIYDLCNGKNSVEDIANKLSNKYKIGYDEALKDINDY
                     LSELEELQLIVK"
     gene            complement(10301..11332)
                     /locus_tag="LLKF_RS00520"
                     /old_locus_tag="LLKF_0097"
     CDS             complement(10301..11332)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030955 - potassium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012449.4"
                     /locus_tag="LLKF_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0097"
                     /product="pyruvate kinase"
                     /protein_id="WP_012896966.1"
                     /transl_table=11
                     /translation="MFSITQTVNYIKSEKHLRSIVATLEQNNIRSIRINLSKLSYQDTL
                     SIIPIIDTVFSEKNEYTLYLDLPFPQNKSRIKEFAISSTNNIVNEGETYTVTNQPDCYN
                     ANKQNTFLLNADNLSGQIDDIIFYADGEGMFKVTSCNIDSIKMVALNTFLIREGKAIMC
                     GYKQEPNDNIQNIVSRLEKIACSKNYLLSFVKNPKDVIDFRTYLKTSSKIIPKIETQQA
                     IENIFDIAEVSDALLVARGDLALNVSFEKLDEAIKRISSASQLNNINTIFCTDILKNMK
                     TRIIPERSELFDLIYMKNNNCSEVVLPAMIHFSYDSTLGIRDEYLASEELRNKIKVIQA
                     ILD"
     misc_feature    11371..11384
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.47"
                     /tool="antismash"
     gene            11432..12004
                     /locus_tag="LLKF_RS00525"
                     /old_locus_tag="LLKF_0098"
     CDS             11432..12004
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014038.4"
                     /locus_tag="LLKF_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0098"
                     /product="CYTH domain-containing protein"
                     /protein_id="WP_012896967.1"
                     /transl_table=11
                     /translation="MIEKEYKILLSSFQFEQIKQILEFSEFREQNNYYYETELFELVSK
                     GLTTRIRTIGDEYFFQIKNKLKNKTHGVTTKEEFEESVKEIPKVIEIEKIENIIGFKLN
                     IDSKYAYNIGVLNTKRYICYMNDCEIALDKNEYFGNTDFELEIEFHENENQALDIIDNL
                     NLDKSNNPVGKYKRFLLEKMKHQKEGY"
     gene            12009..12638
                     /locus_tag="LLKF_RS00530"
                     /old_locus_tag="LLKF_0099"
     CDS             12009..12638
                     /EC_number="3.5.4.25"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013118.4"
                     /locus_tag="LLKF_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0099"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_012896968.1"
                     /transl_table=11
                     /translation="MNNISLSSKILKVSKGQLEIKNGVFTLYAFMIYYEGRCEEHYALV
                     NSKDWKIDEAVPFRINSACVTSEVFGCEKCDCKWQLDEAIHYITEIGFGIITYHPNHEG
                     LGHGIFEKLNSFNELGADNTSYIDLNCEKEDARNFLPALIILDYFKINEVTLLGNNLKK
                     IHFLMENGVNISGIVNLIYNGNNRTTKKYILLKGRKPEHFALRKDK"
     gene            12640..13320
                     /locus_tag="LLKF_RS00535"
                     /old_locus_tag="LLKF_0100"
     CDS             12640..13320
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="LLKF_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0100"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_012896969.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-07,
                     bitscore: 27.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIYLVTGSSGDIGSDICEKILENESNSILGLDIKPSRINNTRYK
                     HIELDLGNLKEIEKVDWEKFNISTVIHTAGVYKSKLIEEYDLSSITYTVNVNVISIVVI
                     IQQLLNKSTNTKLENIIMISSTAEKLGSRDPVYSLSKSAIVGVLKSFEKTLNCRINIVS
                     PGLIDTKMSSENQTIQRKQYHVNNTLAKRMGKIEDVTNLVMFLLSDESSYIWGENIYIN
                     GGML"
     gene            13317..13916
                     /gene="tmk"
                     /locus_tag="LLKF_RS00540"
                     /old_locus_tag="LLKF_0101"
     CDS             13317..13916
                     /EC_number="2.7.4.9"
                     /GO_function="GO:0004798 - thymidylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /gene="tmk"
                     /inference="COORDINATES: protein motif:HMM:TIGR00041.1"
                     /locus_tag="LLKF_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0101"
                     /product="dTMP kinase"
                     /protein_id="WP_012896970.1"
                     /transl_table=11
                     /translation="MKNLLIVFEGLDGSGKTTQIDMLHQWFENKKLEVFTTKQPTDYYR
                     NDKRVRDYLDNGIAPNMYSIALLAAADRTYQISSEIFPKISESNIICDRYLYSSLAFFK
                     ARGIDYKEILMINKGVPIPDVTVFLDVPPERALERVRQRDGEDIKYEEKNELVFNQVRQ
                     NFLDVLPKNALIVDSTLGIDKVHQIITNFVSEVMGK"
     gene            13913..14857
                     /gene="pyrF"
                     /locus_tag="LLKF_RS00545"
                     /old_locus_tag="LLKF_0102"
     CDS             13913..14857
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: protein motif:HMM:TIGR02127.1"
                     /locus_tag="LLKF_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0102"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_012896971.1"
                     /transl_table=11
                     /translation="MMFSDRYIQKVIDTKSHLCVGLDPILEKFPRYILKNAESIYGKTP
                     RGAGYAIFEFNKMIIDIVADKVPAVKPQLAYYEKYDYYGIEAFWKTVDYAKKKKLIVIA
                     DAKRGDIGSTSQAYAETFYKNTADEWSSTLSVDAVTINPYLGSDGLDPFIKLGEENDKG
                     SIILVKTSNPSSGELQDKIEDSENKTISEVVCDYIIKKTNKVGNYGFSDIGAVIGATYP
                     EDLTKYRKLLPRTLFLIPGVGYQGGDVKLLDAAFDNNGLGAIITCSRAIDYAYKDIDLS
                     EREVKNSILEAVDYYNGLINKALVKSKKVYWER"
     gene            14863..15651
                     /locus_tag="LLKF_RS00550"
                     /old_locus_tag="LLKF_0103"
     CDS             14863..15651
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LLKF_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LLKF_0103"
                     /product="hypothetical protein"
                     /protein_id="WP_012896972.1"
                     /transl_table=11
                     /translation="MKKNILESILTKNEVALKEVITKIDYSSSNNNVGTLFYTSFFENL
                     GNKNSDIDIYIFLSSEEELGKKGLRKYSECLGVDVIRVGELELDIEYWTVASVEKILKK
                     LVDSNGLSGNYSDLKILLRIFHGYFLESNEVSSYIMGLLESHDIIKLVKNRIAIEARSL
                     FDEAVKMYEVNEKILSLDCARRCLWECASYMNAHYGKPNLKQKWISKIFIDNKAFGNSD
                     LLDDYINLQIFSNITKENLDNTLLDMFTLIQSMLNVDLFD"
     gene            complement(16118..16978)
                     /locus_tag="LLKF_RS00555"
                     /old_locus_tag="LLKF_0104"
     CDS             complement(16118..16978)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017885.4"
                     /locus_tag="LLKF_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0104"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_012896973.1"
                     /transl_table=11
                     /translation="MSKYLTLVQFSLAHELGHILLGHFDKQGGSLIKSGSPKDPFMEKE
                     ADLFAAEALAPRSLINPYRGQNEIAKCFDISTAAARISLYYKKNYSSEFFNENTTLFNH
                     FQYVERNFFLHSSPRNLLKNNDFATSLTYDFLGVIFHFCKSCHHIDIVENRNYKFCTLC
                     GSNNLLLVSKDNYFEFHETEEQIAFIDKKGNEDMHYTKLKLDADGRLEEKCPRCENEDL
                     RESYCNICGAGIINKCSGNHIGSLWRPSCTGHLLGADRFCPQCGATSTFLEEGLLEEYT
                     TTKNN"
     gene            complement(16987..18128)
                     /locus_tag="LLKF_RS00560"
                     /old_locus_tag="LLKF_0105"
                     /pseudo=""
     CDS             complement(16987..18128)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611914.1"
                     /locus_tag="LLKF_RS00560"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0105"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSGFKRYDEEFKQSLVNLYQTGKTQSELCKDYGVSVSALAKWIKQ
                     YSQVRLEDNTVLTAKQIQELQKRNAQLEEENLILKKASAIFMQNSK"
     gene            <18207..18368
                     /locus_tag="LLKF_RS13100"
                     /old_locus_tag="LLKF_0107"
                     /pseudo=""
     CDS             <18207..18368
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334292.1"
                     /locus_tag="LLKF_RS13100"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0107"
                     /product="tyrosine-type recombinase/integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RHSHASYLINNGIDPTKLSKRLGHSSITTTLDTYSHLYPDTQKSV
                     VSIFDDFE"
     tRNA            complement(18504..18590)
                     /anticodon=(pos:complement(108994..108996),aa:Ser,seq:cga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LLKF_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LLKF_t0010"
                     /product="tRNA-Ser"
     gene            complement(18504..18590)
                     /locus_tag="LLKF_RS00570"
                     /old_locus_tag="LLKF_t0010"
     gene            18750..19943
                     /locus_tag="LLKF_RS00575"
                     /old_locus_tag="LLKF_0108"
     CDS             18750..19943
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /locus_tag="LLKF_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LLKF_0108"
                     /product="argininosuccinate synthase"
                     /protein_id="WP_026138845.1"
                     /transl_table=11
                     /translation="MGNKKIVLAYSGGLDTSVAVKWLTDKGFDVIAACMDVGEGKDLNF
                     IHDKALQVGAVESVVLDCKEEFAKIFVGAALKGNLMYENKYPLVSALSRPLIAQKLVEV
                     AKEKGATAIAHGCTGKGNDQVRFEVAIHSLAPELEVIAPVREWHWAREEEIEYANQNGV
                     PIPADLDNPYSIDMNLWGRAIEAGVLENPWNTCPEDAFFMTNSVEDAPNEAEYIEVEFK
                     EGLPIALNGKSLELHEIIKEVNIIAGKHGIGRIDHIENRLVGIKSREFYECPAAITLLK
                     AHKDLEDLTFVRELAHFKPVLENELANLIYNGLWFNPATKALIAYLDETQKVVNGIVKI
                     KLYKGLATPVGRKSTNSLYSEKLATYTAADEFDQAAAVGFIKLWGLPTQVNAQVNLK"
ORIGIN
        1 cgccgcatca tcaggtgtag cagtagctaa ggcatacttg cttgtccaac cagatttgtc
       61 tttcgaaaca aagacaattg ctgatacagc taatgaagaa gctcgccttg atgcagcact
      121 tgctacatct caaagcgagc ttcaacttat taaggacaaa gcagtaacaa cccttggtga
      181 agaagcagca tctgtatttg acgctcatat gatggtcctc gctgacccag atatgactgc
      241 tcaaattaaa gcagtaatca acgacaaaaa agttaacgct gaatcagccc tcaaagaagt
      301 aactgatatg tttatcggta tctttgaagg aatgactgat aatgcttata tgcaagaacg
      361 tgcagctgac attaaagacg ttacaaaacg tgttttggct caccttcttg gtgttaaatt
      421 gccaagtcca gcgcttatcg atgaagaagt aatcatcgta gcagaagact tgacaccatc
      481 tgatacagct caattggaca agaaattcgt taaagccttt gttactaaca ttggtggacg
      541 tacttctcac tctgcaatta tggctcgtac tttggaaatt cctgctgttc ttggaacaaa
      601 taatattact gaacttgttt ctgaaggtca acttttggct gtttcaggat tgactggtga
      661 agtaattctt gatccatcta ctgaacaaca aagcgaattc cacaaagctg gtgaagctta
      721 tgctgctcaa aaagcagaat gggctgctct taaagacgct gaaactgtta cagctgatgg
      781 acgtcattat gagcttgctg ctaatatcgg aacacctaaa gacgttgaag gtgttaacga
      841 taacggtgct gaagcaattg gtctttatcg tacagaattc ttgtacatgg atgcacaaga
      901 tttccctaca gaagatgacc aatacgaagc atataaagct gtacttgaag gaatgaacgg
      961 taaaccagtt gttgtccgta caatggacat cggtggtgac aaaacattgc cttactttga
     1021 ccttcctaaa gaaatgaacc cattcctcgg atggcgtgca cttcgtatca gcctttcaac
     1081 agctggtgac ggaatgttcc gtacacaatt gcgtgcactc ttgcgtgctt ctgtacacgg
     1141 acaacttcgt atcatgttcc caatggttgc tctcgtaact gagttccgtg cagctaagaa
     1201 gatttatgac gaagaaaaag caaaattgat tgctgaaggt gttccagttg cagatggtat
     1261 cgaagtaggt atcatgattg aaattccagc agcagcaatg cttgcagacc aatttgctaa
     1321 ggaagttgat ttcttctcaa ttggtacaaa cgacctcatc caatatacaa tggctgcaga
     1381 ccgtatgaat gaacaagttt cttaccttta ccaaccttac aatccatcaa tccttcgttt
     1441 gattaacaat gtaatcaaag cagctcacgc tgaaggtaaa tgggctggta tgtgtggtga
     1501 aatggccggc gaccaaactg ctgtaccatt gcttatgggt atggggcttg acgaattctc
     1561 tatgtcagca acatcagtac tccaaactcg ttcacttatg aaacgtttgg attctaagaa
     1621 aatggaagaa ttgtctagca aagctttgag cgaatgtgca acaatggaag aagttattgc
     1681 cctcgttgaa gaatacacta aataatcttt tcaattgatt tgaataaatg aatcctgtca
     1741 gttctgacag gattttttgt aatctattta tcaacaacaa atttactgac agaaaaactt
     1801 atccacgagg ataagttttt tgtattattt taatgttaaa acgtacaata atgataagtg
     1861 gagagaaatg acaaaattaa atttttttga ttactggtta gttggagagg aaggttacag
     1921 tctcattttg atattgattt tacctagcca aattaatatt aatttctggc ttgttttgac
     1981 gagtaagcaa actagcggtt cagtttttaa tattattgcc ctaccaattt tgatggcctt
     2041 gcctaatcta attcaacggg tgatgacctc aaattctatt tattggacta aacaaaaata
     2101 tattattctg atattgaatt gtattttact ttcagtgaca actttttggt tgctaacatt
     2161 gccttttggt cagtaaaaaa gttactgaca aaaaatctgt cagtaactca tacatgctta
     2221 aaatggtaat cctttagtga attttccaag tttttgttca gtaacttttt cgatttggct
     2281 tagcgcatca ttaacagcat cagtaaccat atcttgtaaa gtttcaggat cttcagggtc
     2341 aatcacatca ggtttgatgt cgagagattt caaagtgcgg tcacctgaaa attcaacagt
     2401 tacaaggtct tgagcagatt taccaacaaa agttgtattg gcaatttctt cttgtgaaac
     2461 ttgcatttgc ttttgaagtt tttgtgcttg tttcatcatt gattgcatat tcatcatgga
     2521 aatattacct cttttagaaa ttttgttgaa agcctttcaa cacctctcta ttttaccata
     2581 aaaaaagata ataaaaaaat aggaaaataa aggagaggca aatgaaacgt atgtaaagtc
     2641 actttttatt tactgacaga agtagaaagg tttgaggagc gttctgtgag taaaaaatga
     2701 gacaaaaaaa ctcagcctta gctgagtttt attagtgcgg tgggcgggac ttgaacccgc
     2761 accaagaaaa ttcccgacag gatccttaat cctgcgcgtc tgccaattcc gccaccaccg
     2821 cgaaaacagt acctaaatat aataccattt tcattgttct ctgtcaagaa ttaactcgta
     2881 atttactgac aagattcata gtaaattatg gattataagc tttcataaat tttgaaattg
     2941 tttggcggta aagttcagga tttgtttcaa atgatttggc gtgagcagcc cctttgataa
     3001 ccaataattc ttttggcgtt ccttttttga cagctttata attttcgtaa accatcgaag
     3061 tagggacata agtatcatta cttccatgaa tcaatagaat aggaagttta tcttttgtca
     3121 gtgcttttgt agcactagct tcttggaaaa accaaccttg tcgcaattta ctttcaagag
     3181 aaacactata aacgagtggg aaaggtggaa tattataact ttcttttgct tgataagtaa
     3241 tttcatccca agcgttggta tatccacaat cttcaataat attttttact gacgaaggca
     3301 aagatttttc gctggaagcc atcattactg tagaagctcc catggacagt ccataaagac
     3361 tgatttgact ctcaggattc ttgtcagtta aatagttagc ccaagcaatg atatcaaatt
     3421 tgtcatgata gccaaaagtg atgaatttgc cttccgactg accggcccca cgattatctg
     3481 gcatgagcac attataacct aattcatgaa aaagttgacc atactgacgc atagccgact
     3541 tatcttggcg aaaaccatgt accacgatta ctgtattatt agttttgtgt tcagctggaa
     3601 cataccatgc atcaagtttc agaccatcat ttttaattga ctcagtactt tttgataatt
     3661 tatcgaattt ttgtaccaaa gaataattag gactgctact tttgacctga ccaatctgtt
     3721 gattatttcg aacacaggca atttgataaa aatataaagt tgctcctaaa ttaataacta
     3781 aaagaagagc aaaaaggcca attatcacac gccagatttg tttttttcta aattttttca
     3841 tgaattttat tatacatgaa attcaatata aaaccaaaat taaaagattc tctgttttaa
     3901 taatagattt aatcattcaa ctctaaaaaa taaatttagc ttttttaata aaagtgtgat
     3961 agaatgaaga aaatagaata aatactccac cgggagttaa atcgtacgaa cgattatttg
     4021 catttcagta ggtctgagaa gaaatgtaga tggtcgttct ttttttagct gaggaggcaa
     4081 aaatgacttg gatttattta cttatagcag gaacatttga agtggcttgg gcaacaacaa
     4141 tgaagttgag ccacggcttt tcaaatttga agtttacact actgacgatc atcggaatga
     4201 ttgctagctt tggttttctt gcgctagctc taaaaaaatt acctttaggg attgcttacc
     4261 caatttggac ggggatcgga gccgttggct caatcttaat cggacttatt ctattcaaag
     4321 ataaagtccc accattaact tggcttttca ttgcctgttt agtcgtgggt attattggaa
     4381 taaaagtaac aagcggtcac taaagatgat acagtctttt aattttttag tatatagatt
     4441 tcatgatata ataagagaat tggtaaaaaa taaaagaaat agcaatagaa taatctattt
     4501 gctattttta atgaggagga aaaaatgaaa aacaaaaaaa gcatgatgaa tttagcaatt
     4561 tctaatctct ttttagtatt tttgggtgca ggtttagtca ttcctgtttt gccaaccctt
     4621 aaagaacaaa tgcacttttc aggaacaaca atgggaatga tgatttctat ttttgcaatt
     4681 gctcaattgg ttgcttcacc agtcgctggt gctttatctg ataaaattgg gcgcaaaaaa
     4741 ctcattgcca ttggaatgat tattttttct ttttctgaac ttttatttgg tttagcacaa
     4801 gcgaaaacag gtttttatat ttcgcgagcg ctagggggtg tcgcagctgc gatgctcatg
     4861 ccttcagtta ctgcttatgt ggctgatatg accacaattg ctgaacgtcc taaagcgatg
     4921 ggacttgttt cagcagcaat cagtggtggc tttattattg gtcctggagt gggtggtttt
     4981 attgcccatt ttggaatacg tgttcctttt tatgttgcag caattttagc tttccttggt
     5041 tttattttaa ctatcacaat tttaagagaa ccagagcgca caattgaaag tcatcaagaa
     5101 atcgaaaaag tttcatttct tgatattctc aaaaatccat tatttggttc actctttatt
     5161 ataattttga tttcatcatt tggtttacag gcctttgagt caatttatag tatcatggca
     5221 agtattaact ttggttttag tatgagtgaa attgctttgg taattacagt gagtggaatt
     5281 ttagccctct ttttccaact tttcttattt gatgcaatcg tcaataaaat tggtgaactt
     5341 ggcttgattc aattaacttt ctttgccagt gcaatcttca ttgctgttat tgcctttaca
     5401 aaatcaaatt tagtcgttgc tctttctaca tttgttgttt ttctggcctt tgatttattt
     5461 agaccggctg taacaaccta tctttcaaag catgcgggca atcggcaagg ggtaatcaat
     5521 ggcttgaact cagcctttac gagttttgga aatattttag ggccaatggc cgcgggttat
     5581 atgtttgacc ttaaccattt atttccatat tatatctctg cgattattct actgggaacc
     5641 ggatttttat cactattctt aaacagaaaa aatttcagta aaatctaaat aaaactttca
     5701 attttattat atttataact actaccttgc aaaaagtggt agtttttttc ataaacaaaa
     5761 atttttttga ataaaaaaac ctcctgatgt aatcttatac agtcaggagg aaaaggagta
     5821 aacgtattgg tcactggatt ttctataatt ttttcaaata gggtagaaaa atccatttat
     5881 aaaaggagtc aaggggattt gaacccctgc gccgctttac acggttcgac ggatttcgag
     5941 aactgtgaca ctgttttttt taagagtaaa aaacagaaaa aactgataaa aacaataaat
     6001 agtgctatct catttttcta caattgttta aaaaaggata ctttggtaac tttgaggtaa
     6061 ctagtaaata tataaaacaa aagttattat ttattaaata gtaacttttg ttttatatat
     6121 tttgtcaaag cttctaattt ttgaacatta acctaagggg gattgtaaac agttattaaa
     6181 ataacagtta gactttaaga aatactctta tagaggaatt ttaatatagg taccagataa
     6241 atttcatatt ctgattaaat actaaatgtt taatatcaat gaataatttg aaattttcaa
     6301 tcttattcga tatgttggta aataaagttt tgtacttctg attaaaatag aaatctatat
     6361 aatgttcgga ttttacccaa aagcaaaact atttagaaat taactgtaaa ttatcaattg
     6421 aacttataaa ttattggtga tacaatgaaa ttgtaatgat tgtaattaca aataattaat
     6481 aggaggaaat gacaatgtac aagaaaccaa caatcaaaaa agttgtagat gctaaagtgc
     6541 ttgcacaagt tgttgcgcat gttgttgcgt aattccccat tcagatgaag tatggaacag
     6601 ttatttgttc catattttat tatattgaaa gcataggagg actaaagatt cagccattat
     6661 ttttcaaaaa acaatttata gctattttat taattatact atcattaata tttttagtag
     6721 gatatgattc tataagtcta ttatccattt attatttatt gtttgtttta tcattgacac
     6781 tatttcctta tttaaaattt aaactttctt attcctataa ccttcaagtg atactacttg
     6841 gtatagtttt gtattttcca atatttaata taaatatgaa tgagtggatt ggaaatttta
     6901 caatttccca gtttttaatt agtgctatat ttttattggt tttattatat accattcatt
     6961 ggaaagaact gatgcaacac tataataccc taaactcata tattaaatta acacttccgg
     7021 gaatggtagg ctccttgttt gaatttttct attatattat aggagaagaa attttttacc
     7081 gattctttat aataggctac ttatctaaat cgattaatat tttgttatgt gtgtttatag
     7141 gttcaatatt atttgtatat agtcactatc ttaatagatg ggctaatata atatttacta
     7201 ataaaagtta tatatcatta tttttattag gtgtttttct tagtttagta ttctatcaga
     7261 ctcattcatt attattgtgt attattttac atataattta taatcattca gaattaatag
     7321 tgatatataa gagatttaag gttaaaaata ttgatgagaa gtcagatgtg tttgatgatt
     7381 atgattagag aggagtcgga tgctacagac tattttagct acttataaaa aaaataggcg
     7441 gactcaatta agagcctatc ctatttcatt tatgttccaa agagttttag gttcattgat
     7501 ggggctcttg ctcccagtgt tgttatatta ttttgtattt aatcagaact taagtagttc
     7561 attcctaagt caaaccaacc atatgagtta tattatgtat gttggattag gctattgttc
     7621 ttatggattg tctattgcta ctttaatgaa tgttgggaga gccataatat tggaaataag
     7681 agaaggaact ttagataatt ttttactttc accagcgtct agattagggt attttatagg
     7741 tgtttatctc gaacaatggg ggagagcttt cattgaattt atcataatat ttagttttag
     7801 tattatcctt ggcatgccat tcagtattgc taatcttgta aggattttat ttgcacttct
     7861 aatattatct gtagtgagcc tttgtatggc tgtgttacta tcaacagtta tggtatttac
     7921 gagagacaca ttcattaccc aaaatacact ttttatcata attacagttg ttgcaggggt
     7981 agctttcccg gtttcttatt tacctagtgt agtacaaatt atcagttatt tgatgccatt
     8041 gactccagca attaccattg ttagattact aatttcttat cagtctattc cattgatgtt
     8101 atggttgata atgattgtgg aatcaattat ttatttttat ataggttact tctggtttag
     8161 aagagtagag aaaaaattga ttgaggaggt tctgagttag tgattgaaat gagagatatt
     8221 tctaagagtt ttgtaataaa agaaaagcgg aatggaattt ttaagcgtag taataaagtt
     8281 gagaaaactg ttatttctga tttaaattta aaaatcccaa aaggaaaaat tgttgggctg
     8341 ctgggcatga atggtgctgg aaaaacaacg acaataaaaa tgctgtccac attattactc
     8401 ccgacatctg gttatatata tctggatggg aagaatattt tagaaaatca aaatgagatt
     8461 aaaaataaag ttaatctcat ttcgggagga gaaaaaaatc ttttctggag actgacaggg
     8521 cgtgaaaatt tagaatattt tgcaagttta tacggtattg ataggaaaaa aacaaaacaa
     8581 atcattaaag aaatattaga aatcgtaaaa ttagagtcag cagcggatgt tgtagttgaa
     8641 aagtattcaa aaggaatgaa gcagcggttg caaattgcaa aaggattaat aaacaaccca
     8701 gactatcttt ttcttgatga accaacttta ggtttagatg tattaatagc aaaagaatta
     8761 cgtgagtata tattaaaatt agcaaaaata gagaataaag gtatacttct tacttcgcac
     8821 tatcttcatg aagttgaaga gttgtgtgat tatatttata tcctagaaga ggaacaagta
     8881 aaaaatgaag gaacagcaag tcaaattatt tcaaaactaa ataaagtaat aaaaacacaa
     8941 ataagatttg aacaaagaat tccagaatta tacgatagta ttttatcttt tattacggtc
     9001 aataatgtta actggattga ggaaggaaca ctagaaatta tttctagcga agaaattgta
     9061 ccaaatattc ttgaaataat cggtatttca aattttaaaa aaattatttc cataactagc
     9121 attaagccaa cattagaaga ttgtttaata tcggaatggg aggaaaaact tgagctttaa
     9181 atcaaatctt attgcactga gaggagaaat tattaagcaa aataggaatt accataattc
     9241 actatcctca attttatctc ttttaatatg gccaataatg aaccttatat atattttttt
     9301 cttatataaa tcatttaata tctcttatct ttcaagatat ggtattacta ctattaatga
     9361 attcatcata tttttgataa caggggcgct agtatacaat tgtttttggt ctatggttca
     9421 aagtgccttt tatcttagtt ttgaaagaca aaatggaaca ctagagagtg ttttcatcac
     9481 gcctgtaaat attctatcct atctatatgg tagagcttta ggaggaatta tcacaagttt
     9541 atggatgtac ttttcgtttt catttatcat tttattcctt acacgagaat tttcaataag
     9601 gttagtaatg gtaagtataa ttgcagttgt gattgtagtt ttttctgcaa cagtttgggg
     9661 aggatttata aatgcaattt ttctatcttc aagagatgcg agctatttat ttacaatttg
     9721 tgatgaacca atgcgaatat tttcaggttc tacagtacca attttagctt ttccaatttg
     9781 gggacagatt atttcctata tttttcctgc aacttattgc ttatacatag taaggaatat
     9841 ttatatgtca actttgttta atctcaatat gtatatttat tttatattat cattattaat
     9901 tcttgttgct ctaaccttta ttattgcaaa agtttcttat aaaaatagtc aaaaaaatgg
     9961 tagtttacaa ttatattagc ctaatttaaa aggagaaaaa atgttaaaaa aatcatataa
    10021 atcgcagttg gttaaatttc aaggaaaatt tatgattact gatacaaaaa ttgtatttga
    10081 agtcaatgaa attggggctc gtatctatga cctttgtaat ggtaaaaatt cagttgaaga
    10141 tattgcaaat aaacttagta ataaatataa aattggatat gatgaagctt taaaagatat
    10201 taatgactat ctatcagagt tagaagaatt gcaattaatt gttaaggaat aagaaatctc
    10261 taacagatgt aattctatta gagatttggc agtagtttaa ttaatcaagt atggcttgta
    10321 tcactttgat tttgtttcgt aattcttcac tagctaagta ttcatctcta attccgagag
    10381 tggaatcata agaaaaatga atcattgcag gtagaacaac ttcagaacaa ttattatttt
    10441 tcatgtaaat taaatcaaat aactctgaac gctctggaat tatcctagtt ttcatatttt
    10501 ttaggatatc ggtgcagaat atagtattga tattgttaag ttgtgaagcg gagcttattc
    10561 ttttgatggc ttcatctaat ttttcaaatg agacattaag tgccaaatct ccacgagcga
    10621 cgagtaaagc atcactcact tcggcaatat caaaaatatt ttcaattgct tgctgggttt
    10681 caattttagg tataattttt gatgaggttt ttaagtatgt tcgaaagtca attacatctt
    10741 ttggattttt gacaaaagag agtaaataat tttttgagca agcaattttt tccaatcgtg
    10801 atactatatt ttgaatatta tcattgggtt cttgtttata cccacacata atagctttac
    10861 cttcacgaat taaaaaggtg ttgagggcaa ccatttttat tgagtcaatg ttacaagagg
    10921 taactttaaa cattccctca ccatctgcat aaaaaattat atcgtcaatc tgtcctgata
    10981 aattatcagc atttaacaaa aaagtgtttt gtttgttagc gttataacaa tctggttgat
    11041 tagtaacagt ataagtctct ccttcattaa cgatattgtt tgttgaggaa attgcaaact
    11101 ccttaattct acttttattt tggggaaagg gtaaatcaag atagagtgta tattcatttt
    11161 tttctgagaa tacagtgtca ataatcggta ttattgaaag agtgtcttga tagcttagct
    11221 ttgagagatt gattctaatg ctacgtatgt tattctgctc taaagtagct actatgcttc
    11281 taagatgttt ttctgatttt atgtaattaa ctgtttgtgt aatagagaac attagataca
    11341 ctcctattga tttattttgt taattaaaac attttttaat aaaaaaatca attgtcattt
    11401 tgtaagaata gtataaaaag gggatgctta aatgattgaa aaagaatata aaattctttt
    11461 gagtagcttt caatttgaac aaataaaaca aatattagag ttttctgagt ttagagaaca
    11521 aaataattat tattatgaga cagagctatt tgaacttgta agtaaaggtt taactactag
    11581 aattagaacc ataggagatg aatatttttt tcagatcaaa aataaattaa aaaataaaac
    11641 tcacggtgtt acaactaaag aggagtttga agagagtgtt aaagagattc caaaagttat
    11701 tgaaattgaa aaaatagaga atattatagg atttaagctc aatatagatt caaaatacgc
    11761 ctataacatt ggtgtactta atactaagag atatatttgt tatatgaatg actgcgaaat
    11821 tgcattggat aagaatgaat attttggaaa tactgatttt gaattagaaa ttgagtttca
    11881 tgaaaatgaa aatcaagctt tagatattat agataattta aatttagata agagtaataa
    11941 tccagtcgga aagtacaaaa gatttttgtt agaaaaaatg aaacatcaaa aagaaggtta
    12001 ttgaaaatat gaataatatt agtttatctt caaaaatttt aaaagtttca aagggacaat
    12061 tagaaattaa aaatggtgtg tttaccttat atgcttttat gatttattat gaaggaaggt
    12121 gtgaagaaca ttacgcatta gtcaattcga aagattggaa aattgatgaa gcggtcccat
    12181 ttaggataaa ttcagcatgt gtcacaagtg aagtttttgg atgtgagaag tgtgactgca
    12241 agtggcaatt agatgaagct attcattaca ttacggaaat cggatttgga attataacgt
    12301 atcatccaaa ccatgaagga ttggggcatg gtatatttga aaaattaaat tcatttaatg
    12361 aattaggagc tgacaatact tcttacattg atttgaattg tgaaaaagaa gatgctagga
    12421 acttcttgcc agctttaata attttggatt attttaaaat aaatgaagtg actttacttg
    12481 gtaacaattt aaagaaaata cattttctta tggaaaatgg agtaaatatt tccgggatag
    12541 ttaatttgat ttataatgga aataatcgaa cgactaaaaa atatatttta cttaaaggaa
    12601 gaaaacctga acactttgct ttacgaaagg ataaataata tgggaattta tttggtcaca
    12661 ggaagtagtg gggatatagg tagtgatata tgtgaaaaaa tattagagaa tgaatcaaat
    12721 agtatcttag gacttgatat taaaccaagc agaataaata acacaagata taagcacatt
    12781 gaacttgatc taggaaattt aaaagaaatt gaaaaagttg attgggagaa gtttaatatt
    12841 tcgacagtaa ttcatacagc tggtgtgtac aaatctaaac tcattgaaga gtatgattta
    12901 agctctataa catacactgt aaatgttaat gtaataagta ttgttgtaat tattcagcaa
    12961 cttttaaata aatcaaccaa tactaaacta gaaaatataa taatgatttc atctactgct
    13021 gaaaaattgg gaagtaggga ccctgtttat agcctttcta aatctgctat tgtcggtgta
    13081 ttaaaatcgt ttgaaaagac tttgaattgt agaataaata tagtttctcc aggattaatt
    13141 gatacaaaaa tgtctagtga gaaccaaaca attcaaagaa aacaatatca tgttaataat
    13201 acattagcta aacgtatggg gaaaattgaa gatgtgacaa atttagttat gttcttactt
    13261 tctgatgaat caagctatat ttggggcgaa aatatttata taaatggagg aatgctatga
    13321 aaaatttatt aatagttttt gaaggacttg atggttcagg aaaaacaact caaattgata
    13381 tgttacatca atggtttgaa aataaaaaac ttgaagtttt tacaacaaaa caaccaacag
    13441 attactatag aaatgataaa agagttagag attatttgga taatggtatt gcacctaata
    13501 tgtattcgat tgctttattg gctgcagctg atagaactta tcagatatct tcagaaatct
    13561 ttcccaaaat atctgaaagc aacattatat gcgatagata cttatacagt tcactagcgt
    13621 tctttaaagc tcgtgggata gactacaaag aaattctaat gattaataaa ggtgttccta
    13681 ttccagatgt tacagtgttt ttggatgttc ctccagagcg tgctttagag agagttcgtc
    13741 aaagggatgg agaagatata aagtatgaag aaaaaaatga gttagtattt aaccaagtaa
    13801 gacaaaattt tcttgatgtt ttacctaaaa atgctttaat tgttgattca actttaggga
    13861 ttgacaaagt tcatcaaatt ataactaatt ttgtaagcga ggtaatgggt aaatgatgtt
    13921 ttctgataga tatatacaaa aagtaataga tacaaaatct catctctgtg ttggattaga
    13981 ccctattttg gagaagtttc ctagatatat tttaaaaaat gctgagagca tctatggaaa
    14041 gacccctaga ggagcaggct acgctatttt tgaatttaat aaaatgatca ttgatatagt
    14101 agcagataaa gttccagctg taaaacctca acttgcttac tatgagaagt atgattatta
    14161 tggaatagaa gctttttgga aaactgtgga ctatgctaag aaaaagaagc tgattgttat
    14221 tgcggatgct aagagaggag atatcgggag tacttctcag gcatatgcag aaacgtttta
    14281 taagaataca gctgacgagt ggagctctac tttatctgta gatgcagtaa caattaatcc
    14341 atacttggga agtgatggat tagacccatt tataaaatta ggagaagaaa atgataaagg
    14401 ctctattatt ttagtgaaaa caagcaatcc ttcttcaggt gaattacaag ataaaataga
    14461 ggattctgaa aataaaacta tctctgaagt tgtatgtgat tatattatta aaaaaacgaa
    14521 taaagttggg aattatggat tttcagatat tggagctgtt attggagcaa catatcccga
    14581 agatttaacg aagtatagga aactcttacc tagaacatta tttctaatcc caggagttgg
    14641 ttatcaagga ggagatgtga aactattaga cgcagccttt gataataatg gtttaggagc
    14701 catcataaca tgttcaagag caattgatta tgcttataaa gatatagatt tatcagagag
    14761 agaagtaaag aattctattt tagaagctgt tgactattat aatggattaa taaataaagc
    14821 tttggtgaaa tctaagaagg tttattggga gaggtagagc aattgaaaaa aaatatatta
    14881 gagtcaattt taacgaaaaa tgaagttgct cttaaagaag ttatcacaaa aatagactac
    14941 tcctcttcaa ataataatgt aggaacgctt ttttatacat cattctttga aaatttaggt
    15001 aataaaaatt ctgatattga tatttatatc tttttatcca gtgaggaaga attaggaaaa
    15061 aaaggtttaa gaaaatatag tgagtgtcta ggagtagatg ttattagagt tggggaactt
    15121 gaattagaca tcgaatactg gacagtggct tcggtagaaa aaatattaaa aaaacttgta
    15181 gatagtaatg gactttctgg gaattactct gatttgaaga tattactgag gatatttcat
    15241 ggatactttt tggaatcaaa tgaagttagt agttacatta tgggactttt ggaatcacat
    15301 gatattatta aattagtgaa gaatagaata gctattgaag ctaggtcatt atttgatgag
    15361 gctgtaaaaa tgtatgaagt caatgaaaaa atactgtctt tagattgtgc aagacgctgt
    15421 ctttgggaat gtgcttccta catgaatgca cattatggta aacctaattt gaaacaaaaa
    15481 tggatttcaa agatatttat tgataacaaa gcttttggga atagtgattt acttgatgat
    15541 tatatcaatt tacagatttt ttcaaatata actaaggaaa atttagataa tactttgctt
    15601 gatatgttca cattaataca gagtatgttg aatgtagact tatttgacta aatagtaaaa
    15661 ttaaacataa aataaagctt attatttatt atatagaggc ttttattttg tatattttta
    15721 tagtaaaaat aaattattga ttttaggata aaatatggta taatttattt aacgaaaata
    15781 atgttgccta aataggctac ctcaaaagta gaattcctgc aagagttcta cttttttttg
    15841 ctataaaaaa gacagatact gcaatatctg ccttattagc gactagtggc gctttttgtg
    15901 tttcttgcta cgtttacgag tatctagcca atacttgaaa agttcggtca agcagtttaa
    15961 tgcgagagca gaaacgaaag aaaataatgt taccatagag ctacctcctt tctaactcct
    16021 ttggagaaga taggcaagcg ccagaggtaa ttatatcata aaataataaa aaataactct
    16081 taaattttag actaatttag gagttttctt ttctatatta attattttta gttgtagtat
    16141 attcttctaa tagcccttct tctaggaaag tggaggtagc gccacattgg ggacaaaatc
    16201 tatcagcacc tagaagatga cctgtacatg aaggacgcca aaggcttcct atatggtttc
    16261 cagaacactt gtttattata ccagcaccac aaatattaca ataggattct cttaaatctt
    16321 cattttcaca tctagggcat ttttcttcaa gtcttccgtc agcgtcaagt tttaatttcg
    16381 tgtaatgcat atcttcattt ccctttttgt caataaaagc tatctgttct tctgtttcgt
    16441 gaaactcaaa gtaattatct ttagacacca ataataggtt atttgaaccg cataatgtac
    16501 aaaatttata atttctattt tcaactatat ctatatggtg gcaagatttg cagaagtgaa
    16561 aaattacacc tagaaagtca taggttaatg aggtggcgaa atcgttattt tttaataaat
    16621 ttcttggaga actgtgaaga aaaaaatttc gttcaacata ttgaaagtga ttgaataaag
    16681 ttgtgttttc gttaaagaat tctgaactgt agttcttttt atagtatagg gaaattctgg
    16741 cagctgcagt tgaaatatcg aaacatttcg caatttcatt ttgtcctcga taaggattaa
    16801 tgagggaacg tggggctagt gcttcagctg cgaataggtc tgcttctttc tccataaaag
    16861 ggtctttagg tgaaccgctt tttattaaag aaccaccttg tttatcaaaa tgtcccaaaa
    16921 gaatatgacc tagttcgtgt gcaagagaga actggactaa tgtcaaatat ttagacaaaa
    16981 aatgagctat cttttcttaa aatagttctc ttccttctga tttggagtta atccattgtt
    17041 ggctgaatga ggattatagt tgttataaaa ttgttcgatg tattcaaaac aagagagttg
    17101 cacttcctga atggagtgat aagttcttct gtttatttcc ctttgtttaa ggtacttgaa
    17161 aaacacctca gtcacggcat tatcataagg ataaccaggt ttggaataag aagcaagcaa
    17221 ctgatggtca tctaatattt tcctaaaaga agctgattta aattggcttc cttgatcgga
    17281 atgaaaaaca attggttcct taggcttcct cttatttata gccatctcta atgtgtcaca
    17341 ggcaagttta gcatcaatct tatcacttac tttccaagcg atacatttcc tagaatagag
    17401 gtcaagaata gcgcagagat aaacgtgacg cttaggatcg atagaaatat aagtaaagtc
    17461 ggttgtccac acttgatttg ggactttagg attaaattct tgtttaagca agttatcaga
    17521 agaaaacata ggagctttct ttgatttaaa ccgaggtttg agggttgaca ttttagggag
    17581 tgtcatagac ttgagaagtc gtaagatacg cccttcagaa atattaacgc cataatcacg
    17641 cagaagaatg attttaaaag ctctcgttcc aattcttttc ttagctttca tataaatctc
    17701 aaggagtaat tttctcaagc gttgattttc tatttcacgc tttgagggct tcttgtttat
    17761 gaagttatag taggtggaac gattgacatg taaaacacga cagagcataa ctgtcgtgtg
    17821 ttcaattcgg agtctataga ctgcttttaa tctcacttgg agttttgcat gaatatggca
    17881 ctcgcttttt ttaagataag attttcttct tcgagttggg cattcctttt ttgtaattct
    17941 tgaatctgtt tggcagtcaa caccgtatta tcttcaagac gaacttgaga gtactgctta
    18001 atccattttg caagagcaga gacggagacg ccatagtctt tacagagttc ggattgagtt
    18061 ttacctgttt gatagaggtt gacgagagat tgtttaaatt cctcgtcgta acgtttaaag
    18121 cctgacataa aagtcctttc gtttttgtgt cttcttagac agattataac acactaagtt
    18181 gtgtctactt ttatagtata gctccaaggc actcgcatgc ctcttatttg attaataatg
    18241 gaattgaccc aacaaaatta tcgaaacgtc tagggcattc atctataact accacattag
    18301 atacttatag tcatttgtat ccagatactc agaaatcggt tgtgtcaata tttgatgatt
    18361 ttgaataaaa aaacctccag atgtattgtt atacaaaagg aggaaaagga gtagctaaat
    18421 aaaaagtggt aacttttggt aactgttata agaaaaagtt actgtttgct atgatttgaa
    18481 atgctaaaaa actcaatgtt ttaaggagtc aaggggattt gaacccctgc gccgctttac
    18541 acggttcggc ggatttcgag tccgctgcat taccactctg ccatggctcc actcctttat
    18601 ctaaattaat tatatcacag ttgattctct tcttgaaata atatgaaatt gctagaatga
    18661 aaataaaacg catatttata caaaaatgtt gacaaatgaa taaatatgct gtacaattgc
    18721 atttatatta atttgaaaga agaaaaatga tgggaaacaa aaaaattgtc ttggcatatt
    18781 cgggtggatt ggatacaagt gttgctgtaa aatggttgac tgataaagga tttgacgtca
    18841 ttgctgcctg catggacgtt ggtgaaggaa aagacttgaa ttttattcat gataaggcgc
    18901 ttcaagtagg ggcagtggaa tctgttgttt tggattgcaa ggaagaattc gctaaaatat
    18961 ttgttggagc tgcactcaaa ggaaatttaa tgtatgaaaa taaatatcct ttagtatccg
    19021 ctttgagtcg ccctttgatt gctcaaaaat tagtagaagt agccaaagaa aaaggggcaa
    19081 cggctattgc tcatggttgt acaggaaaag gaaatgacca agtgcgtttt gaagtagcca
    19141 tccattctct tgcgcctgag cttgaagtca ttgctccagt tcgtgagtgg cattgggctc
    19201 gtgaagaaga aatcgaatat gccaatcaaa atggtgttcc tattcctgct gatttagaca
    19261 atccctactc aattgacatg aatttatggg gacgtgcgat tgaagctggt gttcttgaaa
    19321 atccttggaa tacttgtcca gaggatgctt tctttatgac taattctgtg gaggacgctc
    19381 caaacgaagc tgaatatatc gaggttgagt ttaaagaagg attaccaatc gccttaaatg
    19441 gaaaaagctt agaattgcat gaaatcatta aagaagtgaa tattattgca ggaaaacatg
    19501 gaattggtcg gattgaccat attgaaaatc gcctggttgg gattaaatcc cgtgaatttt
    19561 atgaatgtcc tgctgccatt actttattaa aagcacataa agatttggaa gatttaactt
    19621 tcgttcgaga acttgcacat tttaaaccag ttcttgaaaa tgaattagca aacttgattt
    19681 acaatggttt gtggttcaat cctgctacta aggctttgat cgcttatctt gatgaaactc
    19741 aaaaagtagt taacgggatt gtaaaaatta aattatataa aggtttagca acaccagtgg
    19801 gacgtaaatc aactaattcg ctttacagcg aaaaattagc aacatatact gctgcagatg
    19861 agtttgacca agcagcggca gttggattta ttaaattgtg gggtctgcct actcaagtca
    19921 atgctcaagt aaatctcaaa taatagctat aggaaaattt ggaaagtaag agaatggtag
    19981 aaaaactttg gggaggacgt tttgaggcgt cactagataa acaaacggaa gaatttggag
    20041 catcaattaa atttgagcaa cgacttgctc cttttgattt aaaaggctca ttagctcatg
    20101 taaagatgtt gggtgaaaca ggaattatta ctaccgagga atcccaaaaa attgccgaag
    20161 gtctgaaaaa agtagaagaa aagcttctta atggccaaat tgaattcaag atggaaaatg
    20221 aagatatcca tatgaatatg gaatcttatc tt
//
