LOCUS       NC_013947              18063 bp    DNA     circular CON 23-APR-2024
DEFINITION  Stackebrandtia nassauensis DSM 44728, complete sequence.
ACCESSION   NC_013947
VERSION     NC_013947.1
KEYWORDS    RefSeq.
SOURCE      Stackebrandtia nassauensis DSM 44728
  ORGANISM  Stackebrandtia nassauensis DSM 44728
            Bacteria; Actinomycetota; Actinomycetes; Glycomycetales;
            Glycomycetaceae; Stackebrandtia.
REFERENCE   1  (bases 1 to 6841557)
  AUTHORS   Munk,C., Lapidus,A., Copeland,A., Jando,M., Mayilraj,S., Glavina Del
            Rio,T., Nolan,M., Chen,F., Lucas,S., Tice,H., Cheng,J.F., Han,C.,
            Detter,J.C., Bruce,D., Goodwin,L., Chain,P., Pitluck,S., Goker,M.,
            Ovchinikova,G., Pati,A., Ivanova,N., Mavromatis,K., Chen,A.,
            Palaniappan,K., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D.,
            Bristow,J., Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C.
            and Klenk,H.P.
  TITLE     Complete genome sequence of Stackebrandtia nassauensis type strain
            (LLR-40K-21)
  JOURNAL   Stand Genomic Sci 1 (3), 234-241 (2009)
   PUBMED   21304662
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6841557)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Ovchinnikova,G., Munk,A.C., Brettin,T.,
            Detter,J.C., Han,C., Tapia,R., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D., Jando,M.,
            Mayilraj,S., Goker,M., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Stackebrandtia nassauensis DSM 44728
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6841557)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Ovchinnikova,G., Munk,A.C., Brettin,T.,
            Detter,J.C., Han,C., Tapia,R., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D., Jando,M.,
            Mayilraj,S., Goker,M., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (01-OCT-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024545.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 01:07:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,519
            CDSs (total)                      :: 6,464
            Genes (coding)                    :: 6,414
            CDSs (with protein)               :: 6,414
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 0 of 50
            Pseudo Genes (incomplete)         :: 50 of 50
            Pseudo Genes (internal stop)      :: 0 of 50
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name :: Stackebrandtia nassauensis LLR-40K-21, DSM
            44728
            Culture Collection ID             :: DSM 44728
            GOLD Stamp ID                     :: Gc01107
            Funding Program                   :: DOE-GEBA 2007
            Number of Reads :: 81931 Sanger, 851638 pyrosequence
            Assembly Method :: Newbler version 1.1.02.15, Phrap
            Sequencing Depth                  :: 11x Sanger; 29x 454
            Gene Calling Method               :: Prodigal 1.4, GenePRIMP
            Isolation Site                    :: Soil sample from Nassau Bahamas
            Isolation Country                 :: Bahamas
            Latitude                          :: 25.066127
            Longitude                         :: -77.339025
            Oxygen Requirement                :: Aerobe
            Motility                          :: Nonmotile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:48:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6013720
            Orig. end                         :: 6031783
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001778.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082381
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..18063
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="20"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..18063
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18063
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:13063](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..13063)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     misc_feature    complement(346..360)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    1473..1486
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.94"
                     /tool="antismash"
     gene            complement(1498..1806)
                     /locus_tag="SNAS_RS27985"
                     /old_locus_tag="Snas_5657"
     CDS             complement(1498..1806)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040018.3"
                     /locus_tag="SNAS_RS27985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5657"
                     /product="DUF6189 family protein"
                     /protein_id="WP_013020858.1"
                     /transl_table=11
                     /translation="MDLTDFITTSESVIERLVDKLGDDALMRRYADSIRGNSGAGEWQI
                     AMEDLVALLRQHKIPVTATDLRDLNAVFGYLSQSPSEEVSSRAQTSLDNDVSKLTVV"
     gene            complement(1830..2420)
                     /locus_tag="SNAS_RS33440"
                     /old_locus_tag="Snas_5658"
     CDS             complement(1830..2420)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025792.4"
                     /locus_tag="SNAS_RS33440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5658"
                     /product="EndoU domain-containing protein"
                     /protein_id="WP_013020859.1"
                     /transl_table=11
                     /translation="MIGKLLLLLTAVGMSAMAKGGGGKGPRRPKGGRGGGGKSFGLTAD
                     EVDMLLNKSTTSAPPPAPSRKSGGKNGWDDRQPNEPDPRKTMPNLGDTTQRRGHILDGD
                     KNDPTSGGHRYGTNRPGKTEFPKHWTDDQIMDMVNDVARNPDSQPLPRPNGAGYEVQGQ
                     RAGVTIRVILNADGTVWSAHPLDGGLGVKKNPR"
     gene            complement(2442..3155)
                     /locus_tag="SNAS_RS27995"
                     /old_locus_tag="Snas_5659"
     CDS             complement(2442..3155)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013020863.1"
                     /locus_tag="SNAS_RS27995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5659"
                     /product="hypothetical protein"
                     /protein_id="WP_013020860.1"
                     /transl_table=11
                     /translation="MNDSLVAPVEESTTATSGLWLVEDTQTLIDAIESGSWVDGTIGGI
                     TVGLDALSVAMDPLGALASMAIGWLIEHVKPLRDALEEVTGDADKVNSYAKTWENVSTK
                     LLDAGTKLQTAAHKDLETWQSPAANAYSIHADYTTNAVGGIGALAEVMSAATAGAGMLV
                     ATTRAIVRDLIADCVATLLVRIPEWLAEVGLTLGLGTPWVISQAASLIAKWVGRITNYL
                     NSLVSSISNLQALLA"
     gene            complement(3160..3480)
                     /locus_tag="SNAS_RS28000"
                     /old_locus_tag="Snas_5660"
     CDS             complement(3160..3480)
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022280.4"
                     /locus_tag="SNAS_RS28000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5660"
                     /product="type VII secretion target"
                     /protein_id="WP_013020861.1"
                     /transl_table=11
                     /translation="MKVVAKKLRDHADSIDDAIDAFKLSEAASKHVKAGNDAFGTLCQW
                     LPPILDAKRDRLDGLMKKAKDILTDDAKAMRTIADEYETTDKDNAVEVEKTIGDLKDVG
                     WV"
     gene            complement(3486..3902)
                     /locus_tag="SNAS_RS28005"
                     /old_locus_tag="Snas_5661"
     CDS             complement(3486..3902)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014616.4"
                     /locus_tag="SNAS_RS28005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5661"
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_013020862.1"
                     /transl_table=11
                     /translation="MSEEGPRQAEDWVSQLQLRAAKQLEETQRMQAELEKLSITSTNSD
                     KSVTVSIDASGIMTDLKLTEAVKNSSAADLAAEILAMQHKAQNQLGKAASQVVKDSVGL
                     ETATGEAVMNGYRKRFSKKAMEAREEARKKGDKS"
     gene            complement(4066..4782)
                     /locus_tag="SNAS_RS28010"
                     /old_locus_tag="Snas_5662"
     CDS             complement(4066..4782)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013020860.1"
                     /locus_tag="SNAS_RS28010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5662"
                     /product="hypothetical protein"
                     /protein_id="WP_013020863.1"
                     /transl_table=11
                     /translation="MNDNPLIADVDESTTGTSGLWLVEDTQLLIDAIESGSWVDGVIGG
                     ITVGLDVLSAVLDPLGALVSMAIGWLIEHIKPLRDALEKVTGDADKVRSYAKTWDNVSA
                     KLVGAGTDLQSAVHKDLETWQSPAANAYSIHADYTTNAVGGVGALAGVLAAATEGAGML
                     VATTRAIVRDLIAECVTTLLVRIPLWLAEIGLTLGLGTGWVIAQVDSLIAKWVARITSY
                     LNSLVASLSNLQALLA"
     gene            complement(5001..6161)
                     /locus_tag="SNAS_RS28015"
                     /old_locus_tag="Snas_5663"
     CDS             complement(5001..6161)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /locus_tag="SNAS_RS28015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5663"
                     /product="phosphonoacetaldehyde reductase"
                     /protein_id="WP_013020864.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.8e-75, bitscore: 251.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPDDRDVRFGDDAILDTWQLVSKLDGKRAVLICGQHAFDASGA
                     NRCLDELTKVAEVRRWSEFHPNTDAADLIHGLRVVEEFKPDLVLGVGGGSAMDMAKLLC
                     AYQGITDAEQLHAAIRTGAAITERRLKLVLAPTTSGSGSEATHFAVVYIGNDKYSIAGP
                     AMLPDTVILDPKLTLTASPYQRATSGIDALAQATESLWASGASDASRGFARAAIDLLVP
                     ALPEFVNNPSSEVAGRMAQGSHLAGRAIDVSKTTAAHALSYGFTKSYGVSHGHAVALTL
                     GAFIEAHAKATPDNLQPSVDPATHAEGMRTLLAAFGAADAADARARFDAIAEECGLPLK
                     LAEHGITTREQVADLASRVNVERLGNNPVVFTKEQLTELVAAGLSG"
     gene            complement(6251..7372)
                     /gene="aepY"
                     /locus_tag="SNAS_RS28020"
                     /old_locus_tag="Snas_5664"
     CDS             complement(6251..7372)
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03297.1"
                     /locus_tag="SNAS_RS28020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5664"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_013020865.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.6e-23, bitscore:
                     79.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-18, bitscore:
                     66.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDPKRFVDHLSDKGVTLYTGVPDSLLKQLGSHIQAALPRERHV
                     ITANEGAAVGLAIGHYLKTKTPAVVYMQNSGFGNTVNPLLSLADAEVYGVPMLVVVGWR
                     GQPGVKDEPQHVKQGAVQRELVEAMDLPWSILPHDPDEAEKLVDEALAEAVEKNSPYVL
                     LVEKGTFSDAAKLPKADSPLPSREEALIAAATAVGTEAAIVSTTGMLSRELFEYRVNNS
                     LDGDRDFLTVGGMGHASSIALGVAKADPDREVWCFDGDGALLMHLGSLAVIADHAPASY
                     FHVVFNNGVHDSVGGQPTSIDKVDVPAAAKALGYRYATATDSVDGIAAAVAQLREHGGP
                     SLLEIKVRPGNRADIGRPTRSPADSKTAFMNAL"
     gene            complement(7369..8682)
                     /gene="aepX"
                     /locus_tag="SNAS_RS28025"
                     /old_locus_tag="Snas_5665"
     CDS             complement(7369..8682)
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR02320.1"
                     /locus_tag="SNAS_RS28025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5665"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_013020866.1"
                     /sec_met_domain="CTP_transf_like (E-value: 1.5e-12,
                     bitscore: 46.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 3.6e-130, bitscore:
                     431.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.3e-61, bitscore:
                     204.1, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSKPTVYVGMSADLVHPGHINILQRAAELGDVTIGLLTDAAIAS
                     YKRLPHMTYEQRKAVVENIKGVAAVVPQETLDYVENLEKLKPNFVVHGDDWKTGVQQQT
                     RQRVIDALAQWNGELVEVGYTEGISSTQLNESVKEVGTTPNVRLSRLRRLIENKPIVRI
                     MESHSPLTGLIIETTTAEHNGRKVEFDGMWSSSLTDSTARGKPDIELVDPASRMQGIND
                     LFDVTTKPLIYDGDTGGKPEHFSYTVRSLERLGVSAIIIEDKEGLKRNSLFGTGAQQTQ
                     CSIEDMVHKIQVGKKAQVTKDFMVIARIESLILEQGMDDAVKRARAYIDEGGVDGIMIH
                     SRQKTPDEVFEFCELFQKFPKRVPLVVVPTSYNTVVEDEFAKRGVNVVIYANQLMRASY
                     KAMASVATSILENGRSAEVDSQIANIKEALAIIPENLA"
     gene            complement(8824..10533)
                     /locus_tag="SNAS_RS28030"
                     /old_locus_tag="Snas_5666"
     CDS             complement(8824..10533)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0047355 - CDP-glycerol
                     glycerophosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /locus_tag="SNAS_RS28030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5666"
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="WP_013020867.1"
                     /transl_table=11
                     /translation="MPKNLSRFVMRTVLPGALPTAAVVVFALTDLPWLGYGLCLATLVF
                     LTGLFTTVSAGAGRTARAVIVAAVLLGTGLFRDGELNLGLAGAGALLLGLLGVEPLVFK
                     ALRMGRLNTANLPLPRSTVARWATPRTVAMVNIGMIAAFTGCAAFQLSGWPLVAVGVLV
                     VLTQAVLVLRVWVRRRDVAYQTDTAVRAAVEAHAPKFAVHFSGPGSAVYQLLMWLPYFD
                     QLGDPYVIILREGRTAKTFAAATPAPIVVAPSIAAMESMLVPSLRSVFYVNNSMKNTHC
                     VRFGELTHIQLMHGDSEKPASRNPVSAMYDRVFVAGQAGVERYRRYGVKITDEQFRIVG
                     RPQVADVRVDREPIANKKHPTVLYAPTWTGDSADVNFSSLPLGEALVTELLARGATVLM
                     REHPFTRRNVAAGRALERVQELLATDRAKTGRPHRFGAETSGEITLADCFNDADALVSD
                     VSGVVSDWLYSEKPFAVTDMLAEGEEFAESFPLSTASYVIRHDGSNIPEVVSQLLDADP
                     RASERRALKTHYLGDFPADTYTRAFLSAARETYETPRDPRESHERDQAVTAS"
     misc_feature    complement(10506..10519)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    complement(10580..10597)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.18"
                     /tool="antismash"
     gene            complement(10684..12339)
                     /locus_tag="SNAS_RS28035"
                     /old_locus_tag="Snas_5667"
     CDS             complement(10684..12339)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0047355 - CDP-glycerol
                     glycerophosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /locus_tag="SNAS_RS28035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5667"
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="WP_013020868.1"
                     /transl_table=11
                     /translation="MAHLARRLIDVAAPNGLPLAAVAAMLLLPTPWPGYLLSLATLGYG
                     CYRYRADGLGQHLIGRILAIAAILIGLAMGSQGRVGYSWAIAGTLLIAIIAFEPRLVTA
                     LTVRKLETANLPVNRSGLERWNNPRTAFALITVLSLAFIAASAFGWGQWAVTVACGLAA
                     AGLAAGTVEKWLGRRRRAHSGDNDVLAAVKAHAPRFIVHFAAPEGSEYQLRLWLPYFDR
                     LGDDYLIVLRDREFLPDFAPRTAAPIVVAPSITDLESMLVPTVKAVFYVNQSMHNAQCV
                     RFAHLTHIQLMHGDSDKPASYNPISAMYDRIFVAGQAGIDRYHNHGIDIPTAKFRIVGH
                     PQVAKVTVGPRAKAADTPTVALYAPTWTGLSEDVNFCSLPMARDICAALIARGVTVIVR
                     PHPYTRRNPAAARQLDAVERLLAADAEASGREHKWGKTTSETMSLIDCVNAADVMVTDA
                     SGAASDWLYSEKPFAVTDPTGLGEKLAAELPLAKAAYVIRADTANLDEVCAELLDTDSL
                     AADRHKMKAYYLGGFPADAYEEAFFTAARDCYTE"
     misc_feature    12337..12355
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.5"
                     /tool="antismash"
     gene            complement(12344..13063)
                     /gene="ispD"
                     /locus_tag="SNAS_RS28040"
                     /old_locus_tag="Snas_5668"
     CDS             complement(12344..13063)
                     /EC_number="2.7.7.60"
                     /GO_function="GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013308.4"
                     /locus_tag="SNAS_RS28040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5668"
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="WP_013020869.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.6e-13, bitscore:
                     48.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPVVAVLPAGGTGTRLGSALPKQLIKIDGREILAHTLDVFEAT
                     PEVDEIFVFPPREHVAVVEELVKSYGFGKVRGVAPGGADRAASVRAGLAALSDHPSDTK
                     VLVHDAVRPLVDVATVTECVTALDELEAVTVAVPSTDTIVEVDVSGPRELISGIPDRSR
                     LRRCQTPQAFRLRTLARAHELAVADVNFTPTDDCGVVRRYLPHMAIGIVPGSEDNLKIT
                     YPGDLRVAAELLRDRTL"
     gene            complement(13060..13935)
                     /locus_tag="SNAS_RS28045"
                     /old_locus_tag="Snas_5669"
     CDS             complement(13060..13935)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013250.4"
                     /locus_tag="SNAS_RS28045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5669"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_013020870.1"
                     /transl_table=11
                     /translation="MDLRVQRVTKEQVLATYKPRDSWWTVFLVDPIAGPAVRWVSAWRF
                     VTPNLLTVLAFVLGLGSAACFALGTWPWLVAGALLFHLSFTVDCMDGKLARVRGGGNLF
                     GGWLDYICDRLRVLICTVTLFAGQYVQTGKTIYFYFAVAVVFCDMFRYLNALYLKELRR
                     EMRAKLAAAQGLTVDQLQLQDEAQLEIGGDKPAAQSTDAGVTVVDVQGSFKQKFGWFSN
                     FRDFLVRHRVRSHVFSGVEYQMAVFIIAPLTSLVLGVTIAAIVLLLLAEAAVTYKLYLS
                     AADIERQLAA"
     misc_feature    complement(13924..13939)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            14100..14861
                     /locus_tag="SNAS_RS28050"
                     /old_locus_tag="Snas_5670"
     CDS             14100..14861
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="SNAS_RS28050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5670"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013020871.1"
                     /transl_table=11
                     /translation="MTEDAIIEAHDLGVRFAKGRRRNARLREVFTRRNRSTTAAPAPEF
                     WPLRHLSFEIQPGEAVGVIGSNGTGKSTLLRLLAGVLIPDEGQVIRRGRVAPLIALSAG
                     FSGDLTGRENVQLVASLHGMDRKTLKSKFDEIVAFAEVEDHIDTPVRHYSSGMKVRLGF
                     SVISQLEHPILLVDEALAVGDKRFKKKCYKTMRNLLNEGRTLILVSHSERDLTKFCTRG
                     MFLNAGELEVDGTVDDALAAYQLSEDQKVPA"
     gene            14861..16918
                     /locus_tag="SNAS_RS33445"
                     /old_locus_tag="Snas_5671"
     CDS             14861..16918
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040266.3"
                     /locus_tag="SNAS_RS33445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5671"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_013020872.1"
                     /transl_table=11
                     /translation="MRAVLLATTPGARAAVDEETVSQRLIRQIGSFKPRDITVITRPEY
                     RAGLPAGVTVMSSEGVREDLRLLSDLAAAGEPLLLACADTVLPDTAVSAVMSDPTSRSG
                     VLVGQSDGARPLDVPVFKDRGLVLSVSTGFHKVARPNAVASGLLKVSQPFMDDLDHGLG
                     QLRDDSVADLAPGADAWTLVLLALVRGGTKMNAYAVPGLPYGRVAGEAGARALLADIKD
                     TDEDAVRLDLCVKKDDDLFATYCISSYSRHVVKLCAKLRLTPVGVTWLSILFALGAAAL
                     FFQASRPALIGGAVAMYVSFVLDCVDGQLARYKHRFTNFGGWLDMIADRGKEFILYAGL
                     AAGAASQGLTWAWPLALAAITIQTSRHMVDTWYGVLQDQATLRGAVRELTDPVDGYAAP
                     SAGGGSGGGAGALAAKMGRKLGKLSDQFAAHRRSPSYWFKRTIVFPVGERWLVMGVGAA
                     VFDGRIALAALLTWQLIALTYILAGRGLRGWAAKVAVLDDDTATYRDDGPLRSIPMPLS
                     LPPLPVVLFGLVAVTGGVVWAALDHESGWLASLLAAVGLLLSLTTARHRHDGPFDWLIP
                     GILRAAEFGLIITVGLAAEVPSPLTFGLLAVLALYHYDLAARIDKAASPMLSRAAGLGW
                     DGRSLVVLLALIPGIGTWVFAILLGYIALVFVGGALAGRRGKPKAVAVAA"
ORIGIN
        1 gcgccgccac cgacatcggg tggttgtcga ttgccaacgg gatcgcccag gtgtcagttc
       61 tggggctcgt ggtcaccttc gcggctcgca ttcgcggcag ctggttgctg ctcgtgtcgg
      121 cggcggggat ggcgctcggg cagttcgcgg tctcgcaggc gggttcgttg accgtgctca
      181 tcgccgcggt tgtcgtcact tcgctcgtga acgcgccgtt caacgtcgcc acggcgacct
      241 tgcagcaacg ctccaccggc aatcggcatc gaggcagggt cctgggcagg gtgacggcgg
      301 tgaaggccgc gatgttcgtc gtcggtgccc tcggcggcgg ctggctggcc gatctcatcg
      361 gtggtcgtgc cacgctggtg gtctccgcac tcgcctgtct ggccgccctc gtcgccgcga
      421 tcttcctgcg cacatcacat cgagtgtcgg aaatcgacca tgacacaccg ccagccgtgt
      481 ccaactcgat tcccgaggcc aagttagatc gaatcggctc gttgataggg cgcgcggagg
      541 atctcgccga tctgcttgct gtcccgggtc aggaacgccc ggtgaagcct gaatgtttcg
      601 gtcggcgggt cgaggcccag cgtctcccgg tagtgctgac ggcattgttc gaagctgcgc
      661 agtccggcag cggcaccgtt cgcgtggaac tgggcgatca tcgccagctg ccacgtccgg
      721 tccgagtcca cgcactcacc gagcagcgtt tgtatctcgg ctgtcagcag gtgccagtca
      781 ttcgcgagca gccgcgccgt gaagtagtcg cgtttcacgt cgcgataggc ggcgttgacg
      841 gcgaccgcct ggccgtcgag ccatcgactg gcgggaaggc cggttccgaa cggtcctcgc
      901 cacaaccgca tcgcctgtcg gcagagtccg atggcctggg aggcggcacc gttcctgatg
      961 ttgtgccggg catcgaccgc gagcgcgcga aactgatcga ggtccagggc gtgggcggac
     1021 aagtcgagct gatatccatc atggagaact gtcctcagct tcttggactc cccctggtga
     1081 atcatgtcga attcgcgtcg cagcgtactg atgatgctgc gcaggttcgc ggccgcggag
     1141 ctcggcgggt tgtcccacag cagatccgcc agtctgccaa ccgataccgg tgttccacga
     1201 tggagtgcca atgccgcgat cacggcgcgc cgcaaccggg accgcggcgt caccacagtc
     1261 atcggactcg cgaggtggac ttctccgaga acccgaacga aaacttccaa cttccattct
     1321 ccgtaccagc cgacccgtga cgggcggccg gtatccggga agaacccacg gctttcccgg
     1381 gaaccgtgcg ttgaccggcc gcggactcgc tacggggtcc gttctctcca cttcaccgcc
     1441 acaagtctag ggcggcaacg caaaccgctc agcgaacgcg cgttcccggg cgacggttca
     1501 gacgacggtg agtttggaga cgtcgttgtc cagggaggtc tgggctcggg agctgacctc
     1561 ttcgctgggt gattgggaga ggtagccgaa gaccgcgttg aggtcgcgca ggtcggtggc
     1621 ggtgaccggg atcttgtgct gccgtaggag ggcgaccagg tcctccatcg cgatctgcca
     1681 ttcgccggcg ccggagttgc ctcggatcga gtcggcgtag cggcgcatga gggcgtcgtc
     1741 gccgagtttg tcgacgaggc gctcgatgac ggactcgctg gtggtgatga agtcggtcag
     1801 gtccatggca ggcagtctct cttcgctcgt caccgcgggt tcttcttcac gcccaggccc
     1861 ccgtcgaggg ggtgcgccga ccagaccgtg ccgtcggcgt tgaggatcac cctaatggtg
     1921 acaccggcgc gctggccctg gacttcgtag cccgctccgt tggggcgggg tagcggttgg
     1981 gagtcggggt tgcgggcgac gtcgttgacc atgtccatga tctggtcgtc ggtccagtgc
     2041 ttggggaact cggtcttgcc cgggcggttg gtgccgtagc ggtggccgcc ggaggtgggg
     2101 tcgttcttgt caccgtccag gatgtggccc cggcgttggg tggtgtcgcc caggttcggc
     2161 atggtcttgc gcgggtcggg ttcgttgggc tggcggtcgt cccagccgtt cttgccgccc
     2221 gacttgcggg agggcgcggg cggtggggcg ctcgtcgtgg acttgttgag cagcatgtcg
     2281 acttcgtcgg ccgtcagccc gaagctcttg ccgccgccgc cccggccgcc cttggggcgt
     2341 cgggggccct tgccgccgcc gcccttggcc atcgcggaca tgccgacggc cgtcagcagg
     2401 agaaggagtt tgccgatcac aggtgcgtca tccgatcctc gtcaggccag cagcgcttgc
     2461 aggttggaga tgctggacac cagggagttg aggtagttgg tgatccgacc gacccacttg
     2521 gcgatgaggg aggcggcctg cgagatcacc cagggtgtcc ccaggcccag ggtcagaccg
     2581 acctcggcga gccattcggg gatgcggacc agcagggtgg cgacgcagtc ggcgatcagg
     2641 tcgcgcacga tggcgcgggt ggtggccacg agcatcccgg cgcccgcggt ggccgcggac
     2701 atgacctcgg cgagcgcgcc gatgccgccc accgcgttgg tggtgtagtc ggcgtggatc
     2761 gagtacgcgt tggccgccgg gctctgccag gtctccaggt ccttgtgggc cgccgtctgc
     2821 agcttggtac cggcgtccag gagtttggtg gagacgttct cccaggtctt ggcgtaggag
     2881 ttcaccttgt cggcgtcgcc ggtgacctcc tccagcgcgt cccgcagcgg tttgacgtgt
     2941 tcgatgagcc agccgatcgc catggatgcc aaggcgccca acgggtccat cgccaccgac
     3001 agcgcgtcga gaccgacggt gatgccgccg atggtgccgt ccacccagga gccggactcg
     3061 atcgcgtcga tgagggtctg ggtgtcctcc accagccaca gcccggacgt cgcggtggtc
     3121 gactcctcga cgggggctac cagagagtcg ttcacgcggt cacacccatc cgacgtcctt
     3181 gaggtcgccg atggtcttct cgacctcgac cgcgttgtcc ttgtcggtgg tctcgtactc
     3241 gtcggcgatg gtgcgcatgg ccttggcgtc gtcggtgagg atgtccttgg ccttcttcat
     3301 caggccgtcc agccggtcgc gcttcgcgtc gaggatcggc ggcagccact ggcacagggt
     3361 cccgaaggcg tcgttgcccg ccttgacgtg tttgctggcg gcttcggaca gcttgaacgc
     3421 gtcgatggcg tcgtcgatgc tgtcggcgtg gtcgcggagc ttcttggcga cgaccttcat
     3481 gctggtcacg acttgtcacc cttcttgcgc gcttcttccc ttgcctccat ggccttcttg
     3541 ctgaaccgtt tgcggtagcc gttcatgacg gcctcgccgg tggcggtctc gaggcccacc
     3601 gagtccttga cgacctggga cgcggccttg cccagctggt tctgcgcctt gtgctgcatg
     3661 gcgaggatct cggcggcgag gtcggcggcc gaggagttct tgaccgcctc ggtcagcttc
     3721 aggtcggtca tgatcccgct ggcgtcgatg gagacggtca cggacttgtc ggagttcgtc
     3781 gaggtgatgc tcagcttttc gagctcagcc tgcatccgct gggtttcctc cagctgtttg
     3841 gccgcccgca gttgcagctg cgacacccag tcctcggcct gccgagggcc ctcctccgac
     3901 atgtccgcct ccttcaggga actgtgacga gttgtggccg gatcatgcca caagtctgtt
     3961 cagccgccct ggattgtgga tcggccttca tgattttccc cagggattgt ttccagtgcc
     4021 actcagaaac tggcgtgttt ggtcacagcc ggggacggtt cccggtcagg ccagcagcgc
     4081 ctgcaggttg gagaggctgg cgaccagcga gttgaggtag ctggtgatcc gggcgaccca
     4141 cttggcgatc agcgagtcga cctgggcgat cacccatccc gtccccagcc ccagggtcag
     4201 gccgatctcg gccagccaca gcgggatccg caccagcagg gtcgtcacgc attcggcgat
     4261 caggtcgcgc acgatcgcgc gggtggtggc gaccagcatc ccggccccct cggtggccgc
     4321 ggccaggacc ccggcgagcg ctccgacgcc acccacggcg ttggtcgtgt agtcggcgtg
     4381 gatcgagtac gcgttcgcgg ccgggctctg ccaggtctcc agatccttgt ggacggcgga
     4441 ttgcaggtcg gttccggcgc cgacgagttt ggcggagacg ttgtcccagg tcttggcgta
     4501 ggacctcacc ttgtcggcgt cgccggtgac cttctccagc gcgtcacgca agggcttgat
     4561 gtgctcgatg agccagccga tcgccatgga gaccaaggcg cccaacggat ccaagactgc
     4621 cgacaggacg tccaggccga cggtgatacc gccgatcacg ccgtccaccc aggagcccga
     4681 ctcgatcgcg tcgatgagca gctgggtgtc ctccaccagc cacagcccgg acgtgccggt
     4741 ggtggactcg tcgacgtcag cgatcagcgg attgtcgttc acgaggacgc accccttcgg
     4801 cgtccaggtc cgtcgcgttt gccgtgcaca gccatgcctc cacccttcgg taatcgatta
     4861 cccacctgtg cggaatattg ccacagcggt cgatctgaac ggttgaaggc ccggtatgtc
     4921 cgacctgcgg catcaccgga ttccggtgcc gtcgccggtc tggcgcgttt ggtcaggccg
     4981 ccgggtcgac ggcgcgcggg tcagccggac aggccggccg cgaccagttc ggtgagctgt
     5041 tccttggtga acacgaccgg gttgttgccc agccgctcga cgttgacgcg cgaggccagg
     5101 tcggcgacct gttcgcgggt cgtgatgccg tgctcggcga gcttaagggg gaggccgcat
     5161 tcctcggcga tggcgtcgaa gcgggcccgg gcgtcggcgg cgtcggcggc tccgaacgcg
     5221 gccagcaggg tgcgcatgcc ctcggcgtgg gtggccgggt cgacgctggg ttgcaggttg
     5281 tcgggggtcg ccttcgcgtg ggcttcgatg aacgcgccca gggtcagggc gaccgcgtgg
     5341 ccgtggctga caccgtagga cttggtgaag ccgtaggaca gggcgtgggc ggcggtggtc
     5401 ttggagacgt cgatggcgcg gcccgcgagg tggctgccct gggccatccg gcccgcgacc
     5461 tcgctggacg ggttgttgac gaactccggc agcgccggga ccagcaggtc gatggccgcc
     5521 cgggcgaagc cgcggctcgc gtcggaggcg cccgaggccc acaggctctc ggtcgcctgg
     5581 gccagggcgt cgatgccgga ggtggcgcgc tggtagggcg aggcggtgag ggtgagcttg
     5641 ggatcgagga tgaccgtgtc gggcagcatc gcgggaccgg cgatggagta cttgtcgttg
     5701 ccgatgtaga ccacggcgaa gtgggtggcc tcggagccgg agccggacgt ggtgggcgcc
     5761 agcacgagtt tgaggcggcg ctcggtgatg gccgcgccgg tgcggatcgc cgcgtgcagc
     5821 tgctcggcgt cggtgatgcc ctggtaggcg cacagcagtt tcgccatgtc catggcactg
     5881 ccgccgccga cgcccagcac caggtcgggt ttgaactcct cgacgacacg caggccgtgg
     5941 atgaggtcgg cggcgtcggt gttggggtgg aactcgctcc agcggcggac ctcggcgacc
     6001 ttggtcagtt cgtcgaggca gcggttggcc ccggacgcgt cgaaggcgtg ctggccgcag
     6061 atgagcacgg cgcgcttacc gtccagcttg gacaccagtt gccaggtgtc gaggatcgcg
     6121 tcgtcaccga agcggacatc gcggtcgtcg ggcagtgtca cgatcgaact cctcaactcg
     6181 ccggggtttg gtcccacagt aaatgagggg cgggcgggag cgtccgctcc gcccgccccg
     6241 tcaacagttc ttacagcgcg ttcatgaacg cggtcttgct gtcggccgga ctgcgggtcg
     6301 gacggccgat gtcggcgcgg ttaccgggcc ggaccttgat ctccagcagc gacgggccgc
     6361 cgtgctcgcg cagttgcgcg accgcggcgg cgatgccgtc gacggagtcg gtcgcggtgg
     6421 cgtagcggta gcccagcgcc ttggcggcgg ccggaacgtc cactttgtcg atggacgtcg
     6481 gctggccgcc gaccgagtcg tgaacgccgt tgttgaacac gacgtggaag tagctcgccg
     6541 gtgcgtggtc ggcgatgacg gcgaggctgc ccaggtgcat cagcagggcg ccgtcaccgt
     6601 cgaagcacca cacctcgcgg tccgggtcgg ccttggcgac gcccagcgcg atcgagctgg
     6661 cgtggcccat gccgccgacg gtcaggaagt cccggtcgcc gtcgagcgag ttgttgacgc
     6721 ggtactcgaa cagttcccgc gacagcatgc cggtggtcga cacgatggcg gcctcggtgc
     6781 ccacggcggt ggccgcggcg atcagggcct cctcgcggga cggcagcggc gagtcggcct
     6841 tgggcagctt cgccgcgtcg gagaaggtgc ccttctcgac cagcagcacg tacgggctgt
     6901 tcttctcgac ggcctcggcc agcgcctcgt ccacgagctt ctcggcctcg tcggggtcgt
     6961 gcggcaggat cgaccacggc aggtccatgg cctcgaccag ctcgcgctgc accgcgccct
     7021 gtttgacgtg ctgcggttcg tccttgacgc cgggctggcc gcgccagccg acgacgacca
     7081 gcatcggcac gccgtagacc tcggcgtcgg ccaggctcag cagcgggttg acggtgttgc
     7141 cgaagcccga gttctgcatg tagaccacgg cgggcgtctt ggtcttgagg tagtggccga
     7201 tggccagccc gaccgcggcg ccctcgttgg cggtgatgac gtgccgctcg cgcggcagcg
     7261 cggcctggat gtggctgccg agctgcttga gcaggctgtc ggggacaccg gtgtagaggg
     7321 tgacgccctt gtcgctgagg tggtcgacga aacgcttggg atcgacgctc atgccaggtt
     7381 ctccgggatg atcgccaggg cttccttgat gttcgcgatc tgcgagtcga cctcggcgga
     7441 ccggccgttc tccaggatgg aggtggcgac cgaggccatg gccttgtagg aggcgcgcat
     7501 cagctggttg gcgtagatga cgacgttgac gccgcgcttg gcgaactcgt cctcgacgac
     7561 ggtgttgtag ctggtcggca cgaccaccag cggaacccgc ttggggaact tctggaacag
     7621 ctcacagaac tcgaagacct cgtcgggggt cttctgtcgc gagtggatca tgatgccgtc
     7681 gacgccgccc tcgtcgatgt aggcgcgggc acgcttcacg gcgtcgtcca tgccctgctc
     7741 caggatcagc gactcgatgc gcgcgatgac catgaagtcc ttggtgacct gggccttctt
     7801 gccgacctgg atcttgtgga ccatgtcctc gatggagcac tgggtctgct gggcgccggt
     7861 gccgaacagc gagttgcgct tcaggccctc tttgtcctcg atgatgatcg ccgagacacc
     7921 aaggcgctca agggaacgca cggtgtagct gaagtgctcc ggcttgccgc cggtgtcacc
     7981 gtcgtagatc agcggcttgg tggtgacgtc gaacaggtcg ttgatgccct gcatccggga
     8041 ggcggggtcg accagctcga tgtcgggctt gccgcgcgcg gtggagtcgg tcagcgagga
     8101 ggaccacatg ccgtcgaact cgaccttgcg tccattgtgc tcggcggtgg tggtctcgat
     8161 gatgagaccg gtcagcgggc tgtgcgattc catgatccgc acgatcggct tgttctcgat
     8221 caggcggcgc agtcgcgaca gccgtacgtt cggggtggtg ccgacctctt tgacggactc
     8281 gttgagctgg gtggacgaga tgccctcggt gtagccgacc tcgaccagtt cgccgttcca
     8341 ctgggcgagc gcgtcgatga cccgctgccg ggtctgctgc tgaacgccgg tcttccagtc
     8401 gtcaccgtgg acgacgaagt tcggcttgag cttctcgagg ttctcgacgt agtcgagggt
     8461 ctcctgtggc accaccgccg cgacgccctt gatgttctcc acgacagcct tgcgctgttc
     8521 gtaggtcatg tggggcaggc gcttgtagct ggcgatggcc gcgtcggtca gcagaccgat
     8581 ggtgacgtcg cccagctcgg cggccctttg caggatgttg atgtgcccgg gatggacgag
     8641 atcggcgctc atccccacat agacggtggg cttgctcgac aaggtttctc ctcttacttt
     8701 cacacagaga atgctcgcct cgacgtacgg gcgcgcacca tcgcgacacc accggaccgg
     8761 gtcgaggccg gaacgaccga ctgtaccgcg aatgaattct tcgtccggcg cctacccgat
     8821 aaatcagctc gccgtcactg cctggtcgcg ctcgtgtgac tcgcgcggat cacgcggggt
     8881 ctcgtaggtc tcgcgggccg ccgacaggaa cgccctggtg taggtgtcgg cggggaagtc
     8941 gcccaggtag tgggtcttca gcgcccgccg ctcgctcgcg cgcgggtcgg cgtccagcag
     9001 ctgcgagacc acctcgggga tgttggagcc gtcgtgacgg atcacatatg acgcggtcga
     9061 cagcgggaag ctctcggcga actcctcgcc ctcggcgagc atgtcggtca cggcgaacgg
     9121 cttctccgag tacagccagt cggacacgac gccgctgacg tccgacacca gcgcgtcggc
     9181 gtcgttgaag cagtcggcca gcgtgatctc gccggaggtc tcggccccga agcggtgcgg
     9241 gcgcccggtc ttggcgcggt cggtggccag cagttcctgg acccgctcca gggcccggcc
     9301 ggcggcgacg ttgcgacggg tgaaggggtg ttcgcgcatc aggacggtcg cgccccgggc
     9361 cagcagctcg gtcacgagcg cctcgcccag cggcagcgag gagaagttga cgtcggcgga
     9421 gtcgccggtc caggtcggcg cgtacagcac cgtcgggtgt ttcttgttgg cgatgggttc
     9481 gcggtcaacg cgcacgtcgg cgacctgcgg gcggccgacg atgcggaact gctcgtcggt
     9541 gatcttgacg ccgtagcggc ggtagcgttc caccccggcc tgcccggcca cgaacacccg
     9601 gtcgtacatg gcgctgaccg ggttgcggct ggcgggtttc tcgctgtcac cgtgcatcag
     9661 ctggatgtgg gtcagttcgc cgaagcggac gcagtgggtg ttcttcatgc tgttgttgac
     9721 gtagaagacg gagcgcaggc tgggcaccag catgctctcc atggccgcga tggacggggc
     9781 caccacgatc ggggccgggg tggcggcggc gaaggtcttg gcggtgcggc cctcgcgcag
     9841 gatgatcacg tacgggtcgc ccagctggtc gaagtacggc agccacatca gcagctggta
     9901 gaccgccgag cccgggccgg agaagtgcac cgcgaacttg ggcgcgtgcg cctcgacggc
     9961 ggcgcgcacc gcggtgtcgg tctggtacgc gacgtcgcgg cgccgcaccc acacccgcag
    10021 caccagcacc gcctgggtca acacgaccag cacgccgacg gcgaccagcg gccagcccga
    10081 cagctggaag gccgcgcagc cggtgaaggc ggcgatcatg ccgatgttga ccatcgcgac
    10141 ggtgcgcggc gtggcccagc gcgccacggt ggaacgcggc agcggcaggt tcgcggtgtt
    10201 gagcctgccc atccgcaatg ccttgaacac cagcggttcc acgcccagca ggcccagcag
    10261 cagcgccccg gccccggcca gtcccaggtt cagttcgccg tcgcggaaca gcccggtgcc
    10321 caaaagcacg gcggcgacga tgacggcgcg ggcggtgcgt ccggcacccg cgctgacggt
    10381 ggtgaacagg ccggtcagga agaccagcgt cgccaggcac agcccatagc ccagccaggg
    10441 caggtcagtg agcgcgaaca cgacgaccgc ggccgtcgga agtgcgccgg gcagcaccgt
    10501 gcgcatcacg aagcgcgaca aattctttgg cattgaagcg gttcagctcc cggtattcga
    10561 atacttacga cgacccaccg taacaatcgg ctaacgggat tatggcgcac ccttgcgcga
    10621 ctcccaccga ctcgcaacga atggaggttc ttctttgaga ttgagttgtt gcccgcgaag
    10681 atgttactcg gtatagcaat cccgtgcagc tgtgaagaaa gcttcttcat aagcgtcggc
    10741 ggggaagccg ccaagatagt aggccttcat cttgtgcctg tcggcggcca gggaatcggt
    10801 gtcgagcagt tcggcgcaca cctcgtcgag gttggcggtg tcggcgcgga tgacgtaggc
    10861 ggctttggcc agcggcagtt cggcggccag tttttcaccc aatccggtgg ggtcggtgac
    10921 cgcgaacggc ttctcggagt acagccagtc gctggccgcg ccggaggcgt cggtgaccat
    10981 gacgtcggcg gcgttgacgc agtcgatgag cgacatggtc tcgctggtcg tcttgcccca
    11041 cttgtgttcc cggcccgatg cctcggcgtc ggcggccagg agccgttcca cggcgtccag
    11101 ttgccgggcg gcggccgggt tgcggcgggt gtaggggtgc gggcggacga tgacggtgac
    11161 gccgcgcgcg atcagggcgg cgcagatgtc gcgggccatc ggcagcgagc agaagttgac
    11221 gtcctcggac aggccggtcc aggtgggcgc gtacagcgcc accgtcggcg tgtcggcggc
    11281 cttggcgcgg ggcccgacgg tgaccttggc gacctgcggg tgcccgacga tacggaactt
    11341 cgcggtcggg atgtcgatgc cgtggttgtg gtagcggtcg atcccggcct gtccggccac
    11401 gaagatccgg tcgtacatgg cgctgatcgg gttgtagctg gcgggtttgt cgctgtcgcc
    11461 gtgcatcagc tggatgtgcg tcaggtgcgc gaagcgcacg cactgggcgt tgtgcatgct
    11521 ctggttgacg tagaacaccg ctttgacggt ggggaccagc atgctctcca ggtcggtgat
    11581 cgacggcgcc accacgatgg gggcggcggt gcggggcgcg aagtcgggca ggaactcccg
    11641 gtcgcgcagc acgatcaggt agtcgtcgcc gagccggtcg aagtacggca gccacagtcg
    11701 cagctggtat tccgagccct cgggagcggc gaagtggacg atgaaccgcg gcgcgtgcgc
    11761 cttgacggcg gccagcacgt cgttgtcgcc ggagtgggcg cgacggcgtc ggccaagcca
    11821 tttctcgacg gttccagcgg cgagtccggc ggcggccagg ccgcaggcga cggtcacggc
    11881 ccactgtccc cagccgaagg cgctcgcggc gatgaacgcc agtgacagaa cggtgatcag
    11941 ggcgaaggcg gtgcgggggt tgttccagcg ttccaggccg gagcggttga ccggcaggtt
    12001 ggcggtctcg agcttgcgga cggtcagcgc ggtgaccagg cgcggttcga aggcgatgat
    12061 cgcgatgagc agcgtgcccg cgatcgccca ggagtagccg acgcggccct gcgagcccat
    12121 cgcgaggccg atcaggatcg cggcgatggc gaggatccgg ccgatgaggt gctggccgag
    12181 gccgtcggcg cggtaccggt agcagccgta gcccagcgtg gccaagctca gcaggtagcc
    12241 gggccacggc gtcggcagca gcagcatcgc cgccacggcc gccaacggga gtccgttggg
    12301 ggcggccacg tcgatgagcc tgcgcgcgag gtgagccatt cgtctacagt gtcctgtcgc
    12361 ggagcagctc ggccgcgacc cgcagatcgc cggggtaggt gatcttcagg ttgtcctcgc
    12421 tgccgggcac gattccgatc gccatgtgtg gaagatagcg gcgcaccact ccgcagtcgt
    12481 cggtgggagt gaagttgacg tcggcgacgg ccagctcgtg ggcccgggcg agcgtccgca
    12541 gccgaaacgc ctgcggggtc tggcagcgcc gcagccggga gcggtccggg atgccgctga
    12601 tgagttcgcg cggccccgaa acgtcgacct ccacaatggt gtcggtggag ggcacggcga
    12661 cggtgaccgc ctccagttcg tccagcgcgg tgacgcattc ggtgacggtg gcgacgtcga
    12721 cgagcggacg caccgcgtcg tgcaccagca ccttcgtgtc actcggatgg tccgacagcg
    12781 ccgccagtcc ggcccgcacc gaggcggccc ggtcggcgcc gccgggcgcg accccgcgca
    12841 ccttgccgaa accgtaggac ttcaccagtt cctccacgac ggcgacgtgt tcgcggggcg
    12901 ggaacacgaa gatctcgtcc acctccggcg tggcctcgaa gacgtcgagg gtgtgcgcca
    12961 ggatctcgcg gccgtcgatc ttgatcagct gtttgggaag cgccgaaccc agccgtgttc
    13021 cggtgccacc ggcgggcaac accgccacga caggcgaact cacgccgcca gctgccgctc
    13081 gatgtcggcc gcggacaggt agagcttgta ggtgaccgcg gcctcggcca gcagcagcag
    13141 cacgatcgcc gcgatggtca cgcccagcac cagactcgtc aacggcgcga tgatgaacac
    13201 cgccatctgg tactccacac cggagaagac gtgcgagcgg acccggtgcc ggaccaggaa
    13261 gtcccggaag ttggagaacc agccgaactt ctgcttgaag gagccctgga cgtcgacgac
    13321 cgtgacgccg gcgtcggtgg actgcgccgc gggcttgtcg ccgccgatct ccagctgcgc
    13381 ctcgtcctgc aactggagct ggtcgaccgt gagcccctgc gccgcggcca gcttcgcgcg
    13441 catctcgcgc cgcagttcct tgaggtacaa ggcgttgagg tagcggaaca tgtcacagaa
    13501 cacgacggcc accgcgaagt agaagtagat cgtcttcccg gtctggacgt actgcccggc
    13561 gaacagcgtc acggtgcaga tcagcacccg cagccggtcg cagatgtagt ccagccagcc
    13621 gccgaacagg ttgccgccgc cgcgaacccg cgccagcttg ccgtccatgc agtccacagt
    13681 gaagctgagg tggaacagca gcgcaccggc caccagccac ggccaggtgc cgagggcgaa
    13741 acaggccgcc gagcccagtc ccagcacgaa ggccagcacc gtcaacaggt tcggagtgac
    13801 gaaccgccag gccgagaccc accgcaccgc cggaccggcg atagggtcga cgaggaacac
    13861 cgtccaccac gagtcccgtg gcttgtaggt ggcaagcacc tgctctttag ttacgcgctg
    13921 cactcgaaga tccattcgcc gtgacctgac gcacgagatt accaaagcct gcctcggtga
    13981 ctcgggcgcg agaaacggca ccgataatat gtccaatacc gcgcgaatgc tcactggtgg
    14041 agggcaccgc gtaggctcaa gctttccttt ccgttcatgt aaggcgtttc aagcaaacga
    14101 tgactgaaga cgcgatcatt gaggcccacg acctgggagt ccgcttcgcc aagggacgca
    14161 ggcgcaatgc ccggctccgc gaagtgttca cccggcgcaa ccgaagcacg accgccgctc
    14221 cggcccccga gttctggccg ctgcggcacc tgagcttcga gatccaaccc ggggaggccg
    14281 tcggggtcat cggctccaac ggcaccggga agtcgacgct gttgcggctg ttggccggag
    14341 tgctgatccc cgacgaggga caggtcatcc ggcgcggccg ggtggcgccg ctgatcgcgc
    14401 tgtcggcggg gttctccggc gacctgaccg gccgggagaa cgtccagctg gtggcgtcgc
    14461 tgcacggcat ggaccgcaag accctcaagt ccaagttcga cgagatcgtc gccttcgccg
    14521 aggtcgagga ccacatcgac accccggtgc ggcactactc gtccggcatg aaggtgcggc
    14581 tgggcttctc ggtgatctcg cagctggagc acccgatcct gctggtcgac gaggcccttg
    14641 ccgtgggcga caagcgcttc aagaagaagt gctacaagac gatgcgcaac ctcctcaacg
    14701 agggccgcac cctgatcctg gtgtcgcaca gcgaaagaga cctcaccaag ttctgcaccc
    14761 ggggcatgtt cctcaacgcc ggggaactcg aggtcgacgg caccgtcgac gacgccctgg
    14821 ccgcctacca gctctccgag gaccagaagg tgcccgcctg atgcgggcgg tcctgctcgc
    14881 caccacaccc ggcgcccggg cggcggtgga cgaagagacg gtctcgcagc gactcatccg
    14941 gcagatcggg agcttcaagc cccgcgacat cacggtcatc acccgcccgg agtaccgggc
    15001 cgggctgccc gccggtgtca ccgtcatgag ttcggagggc gtgcgcgagg acctgcggct
    15061 gctgtcggac ctggccgcgg ccggggaacc gctgctgttg gcctgcgccg acacggtgct
    15121 gcccgacacc gcggtgtcgg cggtgatgtc cgacccgacc tcccgcagtg gcgtcctggt
    15181 aggacagtcc gatggggctc gtccgctgga cgtcccggtg ttcaaggacc gcgggctggt
    15241 gctgtcggtg tcgaccggct tccacaaggt cgcgcgcccc aacgccgtcg ccagtggact
    15301 gctcaaggtc tcgcagccct tcatggacga cctcgaccac ggcctgggac agcttcgcga
    15361 cgacagcgtc gccgacctgg cgcccggcgc cgacgcctgg acgctggtgc tgctggcgct
    15421 ggtacggggc ggcaccaaga tgaacgccta cgcggttccc ggtctgccct acggccgggt
    15481 cgccggtgag gcgggcgcgc gggcactgct ggccgacatc aaggacaccg acgaggacgc
    15541 cgtccggctc gacctgtgcg tcaagaagga cgacgacctc ttcgcgacct actgcatcag
    15601 ctcgtactcc cggcacgtgg tgaagctgtg cgccaagctg cggctcaccc cggtgggggt
    15661 gacctggctg tcgatcctgt tcgcgctggg ggccgcggca ctgttcttcc aggcttcgcg
    15721 accggcgctc atcggcggcg cggtggccat gtacgtcagc tttgtcctgg actgtgtgga
    15781 cggacagctg gcccgctaca agcatcgctt caccaacttc ggcggctggc tcgacatgat
    15841 cgccgaccgg ggcaaggagt tcatcctcta cgccggtctg gccgcgggcg ccgcctccca
    15901 gggcctgacc tgggcgtggc cgctggcgct ggccgccatc acgatccaga cctcccgcca
    15961 catggtcgac acctggtacg gcgtgctcca ggaccaggcg acgctgcgcg gcgcggtccg
    16021 cgaactgacc gacccggtcg acggctacgc cgccccgtcc gccggtggcg gttccggcgg
    16081 cggcgcgggc gcgctggcgg ccaagatggg ccgcaaactc ggcaagctgt ccgaccagtt
    16141 cgccgcccac cgccgctcgc cgtcctactg gttcaagcgc accatcgtgt tcccggtcgg
    16201 ggaacgctgg ctggtcatgg gtgtcggcgc cgccgtcttc gacggccgga tcgcgctggc
    16261 ggccctgctg acctggcagc tgatcgccct gacctacatc ctggccggac gcggcctgcg
    16321 cggctgggcc gccaaggtcg ccgtcctgga cgacgacacc gcgacctacc gcgacgacgg
    16381 accgctgcgg tccatcccca tgccgctgag cctgccgccg ctgccggtgg tgctgttcgg
    16441 cctggtggcc gtcacgggcg gcgtcgtgtg ggcggccctg gaccacgagt ccggctggct
    16501 ggcctcgctg ctggccgccg tcgggctgct gttgtcgctg acgacggcgc gccaccgcca
    16561 cgacggcccc ttcgactggc tgatccccgg catcctgcgg gcggccgagt tcgggctcat
    16621 catcaccgtc gggctggccg ccgaggtccc gtcgccgctg accttcgggc tgctggcggt
    16681 gctggcgctg taccactacg acctggccgc ccggatcgac aaggccgcct cgccgatgct
    16741 gtcgcgcgcg gcgggcctgg gctgggacgg ccgcagcctc gtggtgctgc tggcgctgat
    16801 ccccggcatc ggcacctggg tgttcgcgat cctgctgggc tacatcgcgc tggtgttcgt
    16861 cggcggcgcg ctggccggac ggcgcggcaa acccaaggcc gtcgcggtgg ccgcgtagcg
    16921 tccgacttcg agggcgcgaa gcggccaacc ggcgccgatc cggcaaccgt tggcccgtct
    16981 caaacgtgca tcaatgggac gctgtgcaca ctcccgtcga tgacggtcgt cagtggcgag
    17041 tgggcattac cattggatgc gcattcgcct ttgtccggcc gcggttacgg gagcacgagg
    17101 gcggtggccc accgtgagtt tcgtgtgtca ctggtttctc ggaacctggc ctgcccgggc
    17161 caggcgctga tacggaggca ccgccccctc agaaaagtga gtcgacgctg tgaacacgac
    17221 gccccctccc agacccttgt gtgtcaccga cagccggtga tggcccgatg acccgcgcct
    17281 cttccggcac gccccgtccc tcgccgagcg tggtgcgcgg agcgcgttcc gacaacgtgg
    17341 tgaagcggct gtacgagcgg tcgctgccgg agtcggcgcg cgggctgatc cgtcggcggg
    17401 tgcccgtcgg cgcgcggttg tgggtgcggc gccggctcgc cgacctcggg gcggccgtca
    17461 tgggcgtgtt ccagctggcc cggcgcgcgg tcacgggctg ggcccggtcg aacaatccgg
    17521 acgagcggat cgtgaccttc gacggtcgca gcgtggtcgc ggtgaccacc gccgccctgg
    17581 cgccgctgtc ggtgcagcgc tcgacgctga agctcgtgtg cgacgcgctc gacgcggtcg
    17641 gggccgagta cttccgggtg cgggggacgg cccggctggc ctcccagatc ggggtcccgg
    17701 agccgcagcg ccgcctggtc gccgccgcga tcgcggggct ggcccgttcg cacgcgatct
    17761 acgtcgccga cccggaacag ccgcagcggt tgcggcggct gcgcggatcc cggccgctgt
    17821 cacgggacca gaacctgctg cggctggtgc ggttccacgc cgacgcctcc ggcggcgtcg
    17881 tcttcggtcc cgaacaccac tgcgacatcg agctgtggca acccgagccc ggcgaccagc
    17941 tgcgggcgcc gcgccccaac cggtgcgtcg agttcgtcgg ccggagcggg gaaaccgtcg
    18001 aggccggtga gtccaccttc acctcgctga ccgggcacgg cgacgagtcc cagccccgct
    18061 atc
//
