LOCUS       NC_013947              24115 bp    DNA     circular CON 23-APR-2024
DEFINITION  Stackebrandtia nassauensis DSM 44728, complete sequence.
ACCESSION   NC_013947
VERSION     NC_013947.1
KEYWORDS    RefSeq.
SOURCE      Stackebrandtia nassauensis DSM 44728
  ORGANISM  Stackebrandtia nassauensis DSM 44728
            Bacteria; Actinomycetota; Actinomycetes; Glycomycetales;
            Glycomycetaceae; Stackebrandtia.
REFERENCE   1  (bases 1 to 6841557)
  AUTHORS   Munk,C., Lapidus,A., Copeland,A., Jando,M., Mayilraj,S., Glavina Del
            Rio,T., Nolan,M., Chen,F., Lucas,S., Tice,H., Cheng,J.F., Han,C.,
            Detter,J.C., Bruce,D., Goodwin,L., Chain,P., Pitluck,S., Goker,M.,
            Ovchinikova,G., Pati,A., Ivanova,N., Mavromatis,K., Chen,A.,
            Palaniappan,K., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D.,
            Bristow,J., Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C.
            and Klenk,H.P.
  TITLE     Complete genome sequence of Stackebrandtia nassauensis type strain
            (LLR-40K-21)
  JOURNAL   Stand Genomic Sci 1 (3), 234-241 (2009)
   PUBMED   21304662
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6841557)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Ovchinnikova,G., Munk,A.C., Brettin,T.,
            Detter,J.C., Han,C., Tapia,R., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D., Jando,M.,
            Mayilraj,S., Goker,M., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Stackebrandtia nassauensis DSM 44728
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 6841557)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Ovchinnikova,G., Munk,A.C., Brettin,T.,
            Detter,J.C., Han,C., Tapia,R., Larimer,F., Land,M., Hauser,L.,
            Markowitz,V., Cheng,J.-F., Hugenholtz,P., Woyke,T., Wu,D., Jando,M.,
            Mayilraj,S., Goker,M., Klenk,H.-P. and Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (01-OCT-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024545.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 01:07:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,519
            CDSs (total)                      :: 6,464
            Genes (coding)                    :: 6,414
            CDSs (with protein)               :: 6,414
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 0 of 50
            Pseudo Genes (incomplete)         :: 50 of 50
            Pseudo Genes (internal stop)      :: 0 of 50
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name :: Stackebrandtia nassauensis LLR-40K-21, DSM
            44728
            Culture Collection ID             :: DSM 44728
            GOLD Stamp ID                     :: Gc01107
            Funding Program                   :: DOE-GEBA 2007
            Number of Reads :: 81931 Sanger, 851638 pyrosequence
            Assembly Method :: Newbler version 1.1.02.15, Phrap
            Sequencing Depth                  :: 11x Sanger; 29x 454
            Gene Calling Method               :: Prodigal 1.4, GenePRIMP
            Isolation Site                    :: Soil sample from Nassau Bahamas
            Isolation Country                 :: Bahamas
            Latitude                          :: 25.066127
            Longitude                         :: -77.339025
            Oxygen Requirement                :: Aerobe
            Motility                          :: Nonmotile
            Sporulation                       :: Nonsporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:48:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5738773
            Orig. end                         :: 5762888
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001778.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082381
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24115
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="19"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24115
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24115
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14115](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14115
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(28..43)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.01"
                     /tool="antismash"
     misc_feature    complement(48..62)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 26.27"
                     /tool="antismash"
     gene            312..1133
                     /locus_tag="SNAS_RS26720"
                     /old_locus_tag="Snas_5403"
     CDS             312..1133
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022022.4"
                     /locus_tag="SNAS_RS26720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5403"
                     /product="phage antirepressor N-terminal domain-containing
                     protein"
                     /protein_id="WP_013020606.1"
                     /transl_table=11
                     /translation="MSYDAPGPYQPRNNPHEIVHIPFHGRVIHTALSADGEPVVILKPT
                     VEEIGLDFSAQLEKLKTRSWAVVTETLISGADGKIYPMVSVNLETWSMLLANVDENKVI
                     LAARPIVIAYQRESAKALRDYWTRGVAANPRYSPREKAEMLAALKGIVDSGFLEAKGRQ
                     LVGRTLGEVPEFDEQTKPLTVAMYLNSLGLKSSAIRRVQSQFGKQLKARYRDQYGCEPP
                     QMEDLVNRHMIKVAQYQEQHRPLFDAVWRSMNRDDGGTTRPKNRPDKNRPK"
     gene            complement(1219..1827)
                     /locus_tag="SNAS_RS33370"
                     /old_locus_tag="Snas_5404"
     CDS             complement(1219..1827)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS33370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5404"
                     /product="hypothetical protein"
                     /protein_id="WP_013020607.1"
                     /transl_table=11
                     /translation="MFRIGDLIMCAYSEGDWCLGHYAGTVGGRIHATVTNPLNAPARVG
                     DLVSVLPGFARAAQGENDVMPVDIHRKLRGHRFYPTMAQLAKLPDLYAQESVPAEDSTV
                     HYRYFAPWGTWWITEFGRDLDAGQAYGYARLADDPAMAEWGTIWLPEIERHLATTPLRS
                     PGGRPIAAVPLLVESDCHFRPGKARDVIPDLADNEQDAQ"
     gene            complement(1945..3378)
                     /locus_tag="SNAS_RS26730"
                     /old_locus_tag="Snas_5405"
     CDS             complement(1945..3378)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000910 - cytokinesis [Evidence IEA]"
                     /GO_process="GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00180.1"
                     /locus_tag="SNAS_RS26730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5405"
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="WP_013020608.1"
                     /transl_table=11
                     /translation="MEIVELDIEQLIPNPDNRPSDAEPDISDLLDSIPIVGLLQPIVAV
                     PTEEPGQHMVVAGHRRRLALIALKHATAPCVIAADADAAQLVASRLAENLNREAMRPTD
                     EARDYEQLALFGWKPERIAKVAGRSKKHVAGALALSKLPEAAQQAADDGTLDLALAAEV
                     AEFAADDPKAMERILKGASSHWGARHAIDEEKRKRDKKDTAEKLKAQLVLDGVRVTTIP
                     KGFPWTSKEAEASTLRDADGNALDPEVVKTQPGFRAFVDPLNPAKPVVYCTDPEAWGFT
                     RTKYTSYVSEAEAQQRAEAEAEDAARAEAHTAARAIRHEFLKQRYATAKAAKPLFPDAL
                     RTVIARPSSMDWSYGFDDLADALAGASIAEAVETAGIDRLTRMLVARWLVLQEANLKAV
                     TSGKRLSDERRALAYLDLLVDDGYTLSDIEQHTHERLTAAIAAEEAELAAQDQAEQDQA
                     DSTHDDAADGDAAVETAAA"
     gene            complement(3785..3982)
                     /locus_tag="SNAS_RS26735"
                     /old_locus_tag="Snas_5406"
     CDS             complement(3785..3982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013015916.1"
                     /locus_tag="SNAS_RS26735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5406"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_013020609.1"
                     /transl_table=11
                     /translation="MVDPRWRKSSRSSGSNSSQCVEVANLIPAIGVRDSKHLDSGVLTV
                     PHNDWIGLVASVKSNQFDSR"
     gene            complement(3975..4793)
                     /locus_tag="SNAS_RS26740"
                     /old_locus_tag="Snas_5407"
     CDS             complement(3975..4793)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="SNAS_RS26740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5407"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_013020610.1"
                     /transl_table=11
                     /translation="MSSNLNPNLAKIQLGRFLKEYRLRAGLKPGDAEVVKIAKASKLKA
                     IEAGRVQSFRYADILAFGSIYDVTRDELDNLTELQEASEKPGWYHQFDVLEAFTTFLTM
                     ESVASKLLIVEIEFITGLFQIPEYTNALREFNLENKGGADKGVKSERQELVLDGEQPPE
                     IVYITSEAALKRQVGGRKVMKAQLEHLVTMSERPGIDILVLPFSLGPHHAMFGPFTIMY
                     FDGGEFPTTVYLESIDGSRYEEGERFIKLYESVSDKTRKQAIPIKDYAHG"
     misc_feature    4835..4844
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            5015..5200
                     /locus_tag="SNAS_RS35420"
                     /old_locus_tag="Snas_5408"
     CDS             5015..5200
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS35420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5408"
                     /product="hypothetical protein"
                     /protein_id="WP_013020611.1"
                     /transl_table=11
                     /translation="MTKQSTAPTPRSSGPVTIPCRSQDCKNGFVAKEVDGQLRAEMCES
                     CDGTGNKTVVAKECDG"
     gene            complement(5221..5979)
                     /locus_tag="SNAS_RS26745"
                     /old_locus_tag="Snas_5409"
     CDS             complement(5221..5979)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5409"
                     /product="transcriptional regulator"
                     /protein_id="WP_013020612.1"
                     /transl_table=11
                     /translation="MTNSTLQAIRKGLLLSQDEFARALREAGQRAGVPNDASKRLVQRW
                     ESGESASPRPVYARALESVTGLPITELGFAVPVPAARVTPNGQGGHDVAASGPDFEVIA
                     PVAHAGKNATSTNYSGIWLSRYEYYSSGRGDTFIGVHYVLVLQHGDRLTARSLPGSSDS
                     PLTMDLTVDGSVVTGTWVEQTHKDGYYRGARYHGAIQMIAEPTGRKISGKWLGFGKEME
                     VNSGPWALIFQDASTNKSTMNKYNKRPPVE"
     gene            6871..7386
                     /locus_tag="SNAS_RS26755"
                     /old_locus_tag="Snas_5411"
     CDS             6871..7386
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5411"
                     /product="hypothetical protein"
                     /protein_id="WP_041625200.1"
                     /transl_table=11
                     /translation="MYDELTLPSDYVLYQRVSLLSDIAVMVECGHPIDCAFDGRHFYYH
                     CTGTEPTGADRIEWYCGRHRLGYADDIDRAVWTQTFRLLPKARRARTAYQRRSLLLATH
                     ALVKVSLSDPRCPVVEWIGHKRLGDRSFHTDHDRALAHRLKDRRVEAAASRHPLRRAAN
                     SLVNPFEM"
     gene            7400..7867
                     /locus_tag="SNAS_RS37285"
                     /old_locus_tag="Snas_5412"
     CDS             7400..7867
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013677394.1"
                     /locus_tag="SNAS_RS37285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5412"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_013020615.1"
                     /transl_table=11
                     /translation="MTTVNAPVPTYALAKRQPAATDPKVWTRLGVHITDLHNEAQGLRR
                     PERLTRAALGAVTLLRSLGVRIELPSGELPTRDLPSALSRPKPSGTLTLTDREREVLGG
                     MAEGKSNAEIGRELFVTEDTIKTHARRLFRKLDARDRAHAVSQGFRLELLT"
     gene            7864..8079
                     /locus_tag="SNAS_RS26765"
                     /old_locus_tag="Snas_5413"
     CDS             7864..8079
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5413"
                     /product="hypothetical protein"
                     /protein_id="WP_013020616.1"
                     /transl_table=11
                     /translation="MNGIAVLAVILFVVIGGPSWILSIFSPAYRKRRRESRAKTANKAW
                     GLLALAGTIALIGLAGLDYIGLIEIK"
     gene            8100..8474
                     /locus_tag="SNAS_RS35990"
                     /old_locus_tag="Snas_5414"
     CDS             8100..8474
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS35990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5414"
                     /product="hypothetical protein"
                     /protein_id="WP_169313926.1"
                     /transl_table=11
                     /translation="MGRIVWRGYRWCGHTDMLRRSRDFPPLHPRHWTRFSATCIGQWAD
                     ERRALDWLWNQMAEAHDHIVAEFPQRAVAIRSEYDDAAQRLCDSDDCACSWSIALPASI
                     RLYVGIVAVYEHPSTIQGDT"
     gene            8612..9778
                     /gene="fxlM"
                     /locus_tag="SNAS_RS26770"
                     /old_locus_tag="Snas_5415"
     CDS             8612..9778
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="SNAS_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5415"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_013020618.1"
                     /sec_met_domain="PCMT (E-value: 3.1e-44, bitscore: 149.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNAMVDGIVKWAKLSDATAAAMRKVERHRFVPAATLKEAYTDDT
                     VVTRRDEAGIATSSASAPWLQGMMLDQLELRPGMTVLEIGAGTGVNAGYVTELVGPSGH
                     VTTIDIQPDVAEDARTALALTGATNVEVICGDGEYGYPANAPYDRVIATAGAWDIPEHW
                     VEQLKPDGLMVVPLRMNGLTRSVAFTRDEHGVWHSKSAVNCGFMPVRGDGEVIETNVQI
                     AKDVVVRIDDGQDLDVEALKDAIADSGEVEWTGILIDAPLDLLDFYMADMDGFCRILAP
                     PSIAERGLAEPMNGWGSMGAATPDAVGYLTKRYGPLHPKLYELGTCAYGPQAQAMVDEL
                     TKRVYAWDRARKSVTGVHIEIHPSGQGDTADALMTIDKRHSRVIVRPA"
     gene            9837..10001
                     /locus_tag="SNAS_RS34480"
                     /old_locus_tag="Snas_5416"
     CDS             9837..10001
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013018832.1"
                     /locus_tag="SNAS_RS34480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5416"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_013020619.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 9.2e-13, bitscore:
                     46.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPTLEATTDIEAFEDLFKLDVRIEAEGPSLSRCNPTNDGCSNSC
                     TSVGCSANC"
     CDS_motif       9837..9947
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKPTLEATTDIEAFEDLFKLDVRIEAEGPSLSRCNPT"
                     /locus_tag="SNAS_RS34480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9948..10001
                     /prepeptide="core"
                     /locus_tag="SNAS_RS34480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-5.10"
                     /molecular_weight="1531.6"
                     /monoisotopic_mass="1530.5"
                     /core_sequence="NDGCSNSCTSVGCSANC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKPTLEATTDIEAFEDLFKLDVRIEAEGPSLSRCNPT"
                     /leader_location="[9836:9947](+)"
                     /alternative_weights="1549.6"
     gene            10001..12889
                     /locus_tag="SNAS_RS26775"
                     /old_locus_tag="Snas_5417"
     CDS             10001..12889
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013018833.1"
                     /locus_tag="SNAS_RS26775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5417"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_244409074.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.2e-159,
                     bitscore: 529.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-11,
                     bitscore: 43.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2e-19, bitscore:
                     68.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSHSTRRGTAFTTPFRVADPRSGLARLPLLHNDPSPNTSIDPVV
                     AEGMFLCSEIHADVSPDSAEQRRATERAFDIRARRRTTPQGVFAGVTELDINVAASTLS
                     VRTEHKVRSYPNPVWVHEIGDRVLDSAAVLHALTYTTNNLAARRGDRLDVQRPSSDPRT
                     GPQRMSVRRTEAVEVVLDVARSGASWKQITTALTQRWPSIQDTTVEVVMRQLTRSGFLL
                     TDLDPVDTCTDPLGHLLAKLPASEPVREPLSWLRAALAEADAHPPGHPARMAALKTARN
                     IADDLFATWRPICTDTAMNAHISIPARVAEEAAQAANVLWRMPPRHDPLAEWHERFLHR
                     YGTGRLVPLLEVCDPVTGLGCDPGNTEVVPPPESTEALARLINVALTSNKMEVQLDAAT
                     ITALDQRRPSDACEPSAELYATVVARDEHDRDAGKFVLAVTNMASPAGSTRARFAGLLP
                     DASVASDPGHGTMTAELAFRPTSHTVAALTGRADNAPWRIPIGTIPQSGDLALDDLAVV
                     SDGARLRLWSTQNNRPVRPVHHNQVGHHLMPPVAAFLCLLGQHGNTGLSPWTWGPFERA
                     PFTPRVRFRDVILSPARWRLPEEVRDAATDRSTWATALRRWRTSARPAPPATVVIDTSD
                     RKLPLDLDRGDDRELLRRYVNRDVTAVTEPPGGPDAVQAVALGERGHHVLEIVVPVSAS
                     HTEETAPPAPALARQSRHSVFTPGSEWLSLAIDAPPSTQDAVLARLADAAHHATGLWHR
                     WFWIRYHTPARGPHLRVRFRGDPRPLGGQLLPLLGDTCANLTTDGLSGGFGIEEYRQEI
                     ERYGGEHAIEYVEDTFHHDANLVAHLLAESSDPDERLALTAASAAEIVRIVADGNRAAL
                     VPHRLERADRRTHARVRPRARSIDDGTPAHRPLWYERTAALTAYRAVLPPDRRIDCASS
                     LIHMHANRLLGDNHRERIARALAVDLIAREAP"
     aSDomain        10415..10681
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SNAS_RS26775_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="5.50E-14"
                     /identifier="RREFam001.1"
                     /label="SNAS_RS26775"
                     /locus_tag="SNAS_RS26775"
                     /protein_end="227"
                     /protein_start="138"
                     /score="43.6"
                     /tool="antismash"
                     /translation="YTTNNLAARRGDRLDVQRPSSDPRTGPQRMSVRRTEAVEVVLDVA
                     RSGASWKQITTALTQRWPSIQDTTVEVVMRQLTRSGFLLTDLDP"
     gene            12886..14115
                     /locus_tag="SNAS_RS33385"
                     /old_locus_tag="Snas_5418"
     CDS             12886..14115
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013018834.1"
                     /locus_tag="SNAS_RS33385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5418"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_013020621.1"
                     /sec_met_domain="LANC_like (E-value: 5.4e-40, bitscore:
                     135.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIEEQVLTVADRLLKPEAVLNAVGRADAASLTRGLAGTALLHA
                     RLAHIDPRFARAAQQHWTAAAAHLKNHRHGFSGIAGGQGGLAASLIIGTGYLPEGNRHH
                     AAAAGASWLAVCARDAADLYQRTDLLTWDVYDAITGLSGIGRVLLAAQSSGYDDVESGL
                     MAALTALTAILEPRDTGRPGWWMPAENHPNLARIHPSGAATTGLAHGVAGPLALLATAH
                     VAGWSVPGQAEGIDHAADWLLDWRRDDGTWPPSVTGDELDTAQPPSTPGRADAWCYGTP
                     GISRSLHLAGLALDDPHLQAAAISAVDTMGSRKPAEWDVEGPTLCHGYAGFLQSAPDNH
                     PVAGAVVEAISAYFDSSHRFGFQHRDQGQTHVEPGLLTGAAGVALALAEHQDLPTPGTP
                     ASWECLLNLS"
     gene            14140..14529
                     /locus_tag="SNAS_RS26785"
                     /old_locus_tag="Snas_5419"
     CDS             14140..14529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013018835.1"
                     /locus_tag="SNAS_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5419"
                     /product="hypothetical protein"
                     /protein_id="WP_013020622.1"
                     /transl_table=11
                     /translation="MSEPTTATEPSAPTPKSDGGQAGDLCRRILAVHDRVSTASTDLNR
                     LFAQTAIELSGLLADGYQLHHKTLTAGFDDAAFQLHHMLVALSNVQIDVSTVTDTAAKL
                     PTLTKAFAHERHIDLNATPPDEPAP"
     gene            14539..15381
                     /locus_tag="SNAS_RS33390"
                     /old_locus_tag="Snas_5420"
     CDS             14539..15381
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025784.4"
                     /locus_tag="SNAS_RS33390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5420"
                     /product="DddA-like double-stranded DNA deaminase toxin"
                     /protein_id="WP_013020623.1"
                     /transl_table=11
                     /translation="MTTFEQLVAAVNNAVAEVGEARTLAAQGIQHVARSSTRMENIACG
                     SSSYRLRDVLAALTAAITAIEHSNTAAASASAQLNTYLAAIGNSTTTVEAQPEAAPPPA
                     AAESLDSTPRLPDGGIDFHALAKRLGLLEARPTEQPPFDPRRFNPACWQGLKPYDQAGT
                     AEGNLFIAPGKRWNTRPMQASKLEVGPQSDLHPQWRSRKAPWHIEGKIAAYMRQKGFTD
                     GCVYLNARPCSGPDGCARNLPDLLPVGSTLHVHARYIDRTGETRFYYREYRGTGKALT"
     misc_feature    14608..14610
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15378..15617
                     /locus_tag="SNAS_RS26795"
                     /old_locus_tag="Snas_5421"
     CDS             15378..15617
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5421"
                     /product="hypothetical protein"
                     /protein_id="WP_013020624.1"
                     /transl_table=11
                     /translation="MTDTYDLHPEPEEFDDIPVTDDPELNRELLRAVLDGTDPAQIMQR
                     VSKAGIVPPEPGRDDWAFAIIHEGNPETGTVIWD"
     gene            complement(15646..16263)
                     /locus_tag="SNAS_RS33395"
                     /old_locus_tag="Snas_5422"
     CDS             complement(15646..16263)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="SNAS_RS33395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5422"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_013020625.1"
                     /transl_table=11
                     /translation="MTGIEGEGHTPPSSVARHRLRQLRDRLGLTVDDVVERCRRLGATD
                     VTDNIIWNIESGRRKLSLDVTVTLAAALGVPFMSLLVPDDPDATIHATPAVPVSPNRFA
                     AWSTGTAPLPGADAGAFAEAAADLPLPGREPEDVDWQSRVRWAITHIDDHAETAAQKLN
                     QSARDFLTAFEVVATESPSAKDALSLLQRRLGSTPDASKDDP"
     gene            16635..17219
                     /locus_tag="SNAS_RS35430"
                     /old_locus_tag="Snas_5424"
     CDS             16635..17219
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS35430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5424"
                     /product="hypothetical protein"
                     /protein_id="WP_013020627.1"
                     /transl_table=11
                     /translation="MTYDDAHHPAAAEALEEYCQHAIETMTTHGGMMPAPTVYMFSGDG
                     EHLDSLQGYVIARPSHSGGDAGDAIRQLGLLPGVLRCDRIVIAWEHRTTATLLGRGGDH
                     QTGIAAVEAARDHRVVTWRPFTVHHGDYGIHGTRSMIATWGRAQELRTRLPVPIADAVR
                     VWTNASCASITSTVAKLEAAGYLVSLFHEGW"
     gene            17288..18580
                     /locus_tag="SNAS_RS34490"
                     /old_locus_tag="Snas_5425"
     CDS             17288..18580
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018381.4"
                     /locus_tag="SNAS_RS34490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5425"
                     /product="DUF1173 family protein"
                     /protein_id="WP_244409182.1"
                     /transl_table=11
                     /translation="MSLDDLYRDRARCARILASARAEDGHAWCECNCPQSKLVIRCRQG
                     VWHLARWPGDRIGHAANCPFRGIDPGLTGRAAFSESAIQESRDGVHLRIATSLTTDLGT
                     RSKPGLGDHHRGGGSNRHRLTLLGLLEYLWEESRLNEYRSGSRLWWGRCHHALVSQVEN
                     SFLGDQPLSEVMYVVPPFRKESAANNEATWNAFAAGLGSKNRRSRLGIVLGEFKDAAAT
                     SRGYRIRLRNFRKPIFVTRKLWDTLTMRFQSAFTSQMTAQGRQVGLWVVDKATRGYLRL
                     STAGIMATTQSWIPVDSGYELTMANALADANRSFLKPLRYQHCDVVLPDFVITDTNPRT
                     YIEVWGIVGRESYERRKQEKQDYYKQRGLQLIEWNVSESIPEVPRLLSCRVSSRLSTED
                     AVTSSSGQFVAGLSSSDSHGNEQFPQATPAL"
     misc_feature    18446..18448
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18679..19218)
                     /locus_tag="SNAS_RS26810"
                     /old_locus_tag="Snas_5426"
     CDS             complement(18679..19218)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5426"
                     /product="hypothetical protein"
                     /protein_id="WP_013020629.1"
                     /transl_table=11
                     /translation="MVAFLTNRSLHRSGAKERASGRSLDACIDFVGISLHYLTVTQEYI
                     VELASVPNTPGGEEGAGLTDDIPTMRRNISSLDKEYLIAAVRAESFAPTQSVFSFIHTA
                     QECQSEMKDLLNKSWSRNPPVDWDATRRGVAMRHDAAAQDMTEQLRLYGAQHTYLDSFP
                     GKSSRPESEIERTPPT"
     gene            19533..19967
                     /locus_tag="SNAS_RS26815"
                     /old_locus_tag="Snas_5427"
     CDS             19533..19967
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5427"
                     /product="hypothetical protein"
                     /protein_id="WP_013020630.1"
                     /transl_table=11
                     /translation="MQKNNGHRIEVPPYIAEQISKFAKQNRLSRNEAVEEIFAAGLEAL
                     GANPTDFSGNGPYWLESTSVRHNADGEPELDPSWVPTESALTLEDARRQLVYHVIRGSK
                     DHMSYQGHGELLESTPLGLPVKYDNQYWRIVKRTKPTPQL"
     gene            complement(20099..21148)
                     /locus_tag="SNAS_RS26820"
                     /old_locus_tag="Snas_5428"
     CDS             complement(20099..21148)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013700.4"
                     /locus_tag="SNAS_RS26820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Snas_5428"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_013020631.1"
                     /transl_table=11
                     /translation="MSESHPLTLKIGLAIAAVMVLPLVAVVALAIVAVSTDDAAESGGV
                     TCSITKKTATALGLSKTQLGHAATIYEVALDKSMGRRAAIIGIATAIQESTLHNYGHLG
                     DRNDHDSLGLFQQRPSAGWGSPTQITNPKYAAGKFFDSLKKVSGWQSLPLTVAAQTVQG
                     SAFPDAYAKHEPKAKKIVNTLENPRICAAGTGSGKWAKPVNAGIVSGYRTSERPDHHGI
                     DFGAARGTTIKAVGAGTVKTVTCNASTGAGQPYSCNIDGGVHIMGCGWYVEIQHADKTV
                     TRYCHMVSRPSVNEGQKVNAGQKLGKVGNSGNSSGPHLHFEAHGDYPADPGNAIDPRKY
                     LKDRGISVS"
     misc_feature    21310..21326
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            complement(21323..21673)
                     /locus_tag="SNAS_RS26825"
                     /old_locus_tag="Snas_5429"
     CDS             complement(21323..21673)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5429"
                     /product="hypothetical protein"
                     /protein_id="WP_144300650.1"
                     /transl_table=11
                     /translation="MTQRLGLPPNAGLDDLVAAISRIRGRVFEIRRMTVRLPPTRHGVW
                     IATDVADHLVVTAVATPTCLLHDLAHVILGHTITHSEIPQTITYTSYQEKAATHLADHL
                     AQTYPRLTAAKK"
     gene            complement(21808..22317)
                     /locus_tag="SNAS_RS26830"
                     /old_locus_tag="Snas_5430"
     CDS             complement(21808..22317)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5430"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_013020633.1"
                     /transl_table=11
                     /translation="MNDPRNHSSNSDHDDAHSGRGRLARRLDALFVNQGVSNSKVADDL
                     TNAGVKVSHGYLSLLRRDQRDDPSYRLLQALADYFGVTTEYFSGPDPDYQDNEVAAVME
                     IANAERVRAIAHHASGLSPESVELIQLMIAKARAAEGLPPIEAKAPRSENAGNDPDVSS
                     SENPAT"
     misc_feature    22388..22402
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            22520..22858
                     /locus_tag="SNAS_RS26835"
                     /old_locus_tag="Snas_5431"
     CDS             22520..22858
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5431"
                     /product="hypothetical protein"
                     /protein_id="WP_013020634.1"
                     /transl_table=11
                     /translation="MSTTMHVINASSDALAALAGLADLGDIPNPKPKDPTGGSKGLNQL
                     ISYSKWGVLITCAICAVASGAFMAAGSMSNRPNAVDKGKVSLLWSLAGVIVSAMAIPVV
                     NSVFGAAS"
     gene            22887..23606
                     /locus_tag="SNAS_RS26840"
                     /old_locus_tag="Snas_5432"
     CDS             22887..23606
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SNAS_RS26840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Snas_5432"
                     /product="hypothetical protein"
                     /protein_id="WP_013020635.1"
                     /transl_table=11
                     /translation="MSQSEFFAKPPRRGRIVVAVITGLVLVAAGITVGVIVTGDDSSQT
                     ETASPGSSASPSASTDGAESSLPIVAGEDTEAGVGVGYPHSKVGAVSAAVEFTSQVLST
                     LDPDRAVEVAEVANDPDNGFDPADAANTVTAMREQMGLPPTGDVPEGASIVTAPVAYQL
                     RDETTDSMVVLLLCYVTKDTGSGEPQEDVGVFTMPMAWNGDDWKLVRSDDDTDYTDLNT
                     TPGSDEARAKGWIGVTR"
     misc_feature    complement(23919..23933)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 atgcaatttc gccgcaatca tgtgaccggg cacacgcgtt cgaagacccc tacatcttgt
       61 ggtgtcacgt cacagtgacg tactagaatt agcgtaggga ggcaagggtg tcaggcaggt
      121 atccgagttg aacagcttag aaatctgact gtcctttccc gccgcttcac accttgaagt
      181 gctttacggc tcgccattat tagtatgtat atgtcggggc tatgcgggcg ttcacaagac
      241 gctgacacgc aaaacccgcc tggtgctaag cccaccaggc gggtgaaatc actagcttta
      301 agaaggatcg tatgtcctac gatgcccctg gtccatacca accccgcaac aatcctcatg
      361 agattgtgca catcccgttc cacggccgtg tcatccacac cgcgctcagc gcggacggtg
      421 agccggtggt catcctgaaa ccgaccgtcg aagagatcgg gctggacttc tcggctcagc
      481 tcgaaaagct caagaccaga tcgtgggccg tcgtgaccga aacactcata agcggcgcag
      541 acggcaagat ctacccgatg gtcagcgtca acctcgaaac ctggtcgatg ctgttggcca
      601 acgtcgacga gaacaaggtc atcctcgccg cgcggcccat cgtgatcgcc tatcaacgcg
      661 aaagcgccaa ggcactgcgg gattactgga cccgaggcgt agcggccaat ccgcgctaca
      721 gcccccgcga gaaggcggaa atgctggcag cactgaaggg aatcgtggat tcagggttcc
      781 tggaggccaa gggacggcaa ctggtgggac ggactcttgg cgaggtccca gagttcgacg
      841 agcaaaccaa gccgttgaca gtggcgatgt acctgaacag cctcgggctg aaaagctcgg
      901 cgatccgcag ggtacaaagt cagttcggta agcagctcaa ggcccgctac cgcgaccagt
      961 acggttgcga gccaccacag atggaagatc tcgtgaaccg ccacatgatc aaggttgccc
     1021 agtaccagga gcagcaccgg cccttgttcg acgctgtgtg gcggtcgatg aaccgcgacg
     1081 acggcggaac caccaggccg aagaaccgac ccgacaaaaa ccgaccaaag tagaaccctt
     1141 gcagggttgg ctcggtcatt ctcggccggg ccaacccgaa tctggcacgc tagcggccat
     1201 cgttgatgtg gaggttcgtc actgtgcatc ttgttcgttg tcggcaaggt cgggaatgac
     1261 gtctcgggct ttgccggggc ggaagtggca gtcgctttcg acgaggagcg ggactgcggc
     1321 gatggggcgg cctccagggc tgcgcagtgg ggtggtggcg aggtggcgtt cgatttcggg
     1381 tagccagatt gtgccccact cggccatggc ggggtcgtcg gcaagtcggg cgtacccgta
     1441 agcctggccc gcatcgaggt cgcggccgaa ttcggtgatc caccaggttc cccacggcgc
     1501 gaagtaccgg tagtggacgg tgctgtcttc tgcgggaacg gactcttggg cgtacaggtc
     1561 gggcaatttc gccaactgcg ccatcgtggg gtagaaccgg tggccgcgca gcttgcggtg
     1621 gatgtccacc ggcatcacgt cgttctcgcc ttgcgcggcg cgggcgaaac ccggaagtac
     1681 cgacaccaga tctccgacgc gggctggcgc gttgagtggg ttggtgaccg tggcgtggat
     1741 ccggccgccg accgtcccgg catagtggcc caggcaccag tcgccttcgc tgtaggcgca
     1801 catgatcaga tctccgatac gaaacatggg actctcctca aaggagtaga tgaaggagcg
     1861 cctcaacccc gtgatgggtt gaggcgctat gaggaccggt ggcgggccgc gatgcgctgc
     1921 ccgccaccgg caggaacgaa ttggtcaggc ggcggcggtc tcgactgcgg cgtcaccgtc
     1981 agcggcatcg tcgtgagtgc tgtcggcctg gtcctgttcg gcctggtctt gtgctgccag
     2041 ctcggcctct tcggcggcaa tcgccgccgt aaggcgctcg tgggtgtgct gctcgatgtc
     2101 ggacagggtg tagccgtcgt ccacgagcag gtccaggtag gccagggcac ggcgttcgtc
     2161 ggagaggcgt ttgcccgagg tgacggcctt gaggttggct tcttgaagta ccagccaccg
     2221 ggcgacgagc atgcgcgtca ggcgatcgat ccccgccgtt tccacggctt cggcaatcga
     2281 ggcgccggcg agggcatcgg ccaggtcatc gaagccatac gaccaatcca tcgacgacgg
     2341 gcgcgcgatg acggtccgca gcgcgtccgg gaacagcggc ttggcggcct tggcggtggc
     2401 gtagcgctgc ttgaggaact cgtgccggat agctcgggcc gcggtgtgtg cctcggcgcg
     2461 ggcggcgtct tcagcttcgg cctcggcgcg ttgctgggct tcggcttcgg agacgtagga
     2521 ggtgtacttc gtgcgcgtga acccccaggc ttcggggtcg gtgcagtaca cgaccggctt
     2581 cgccgggttg agcggatcga cgaaggctcg aaaccccggc tgagtcttca cgacttcggg
     2641 gtcgagggcg ttgccgtcgg cgtcccgcag ggtgctggct tcggcttcct tcgaagtcca
     2701 cggaaacccc ttcgggatcg tggtgacccg gacaccatcc agcaccagct gcgccttcag
     2761 cttctcggcg gtgtccttct tgtcccgctt gcgtttttcc tcgtcgatgg cgtgccgggc
     2821 tccccagtgc gagctggcgc ctttgaggat gcgctccatg gccttggggt catcggcggc
     2881 gaattcggcg acctcggccg ccagggcgag atcgagggtc ccgtcatcgg cggcctgctg
     2941 cgcggcttcg ggcagcttcg acagcgccag cgctccggcc acgtgtttct tgctgcgccc
     3001 ggcgaccttg gcgatccgtt cgggtttcca cccgaacagg gccaactgct cgtagtcgcg
     3061 ggcctcgtca gtgggacgca tcgcctcacg gttgaggttt tcggccaacc gcgaggccac
     3121 cagttgcgcg gcgtcggcgt cagcggcgat gacgcacggt gcggtggcgt gcttcagcgc
     3181 gatcagggcg agccggcgtc ggtgcccggc caccaccatg tgctgacccg gctcctcggt
     3241 cgggaccgcg acgatcggtt gcagcagccc gacgatcggg atcgagtcca gcaggtccga
     3301 gatatcgggt tcggcgtcgc tggggcggtt gtcgggattg ggaatcagct gctcgatgtc
     3361 gagctcgacg atttccatga ccgtgtcctt tccagacgtg gaagacgcga cccgcggaca
     3421 gcgggccgct ttctgacagc ggtgccgcca gccgcctgga aagcggggcc gacaaggaac
     3481 aagcccgaaa accccgaccg aacccgaaaa ccccggcggg gttttcgggc gccttgcgac
     3541 cccgcgacag gcggctacac tccaccgcca gaaagcggaa cgcatggacg gtgcgactct
     3601 gaatctggaa aggacagtcg cgtcgatgtt cgacgcccgg cattgccagt gcagacgccg
     3661 atggccccct gcctgccagc agagggccct tcgttgggat gcgcaaagtt cgcgactggt
     3721 agttagtctg gagaccgatt cagtagcacc gtcggggccg gctcacacgc tagggcctga
     3781 cgcgtcatcg tgaatcgaac tggttggact tgaccgaagc gacaagaccg atccagtcgt
     3841 tgtgggggac agtgaggacg ccgctgtcga ggtgcttgga atcccggaca ccgatggccg
     3901 gaatcaggtt cgctacctca acgcattggc tgctgttgct gccgctgctg cggctcgact
     3961 tgcgccaccg tgggtcaacc atgtgcgtaa tccttaatcg gtatcgcttg cttgcgggtc
     4021 ttgtcggaga cgctttcgta gagcttgatg aacctctcgc cctcctcgta gcggcttcca
     4081 tcgatggatt ctagatacac cgtggtgggg aactccccgc cgtcgaagta catgatggtg
     4141 aacggtccaa acatggcgtg gtgcggtccc aggctgaacg ggagcacgag gatgtcgatg
     4201 cccggccgtt cggacatcgt cactaggtgc tcaagctgcg ctttcatcac tttccgtccg
     4261 ccaacttgac gcttcagggc cgcctcgctg gtgatgtaga cgatctcagg tggctgctcc
     4321 ccgtccagga ccagttcctg acgttcggat ttgacacctt tgtcggcgcc acccttgttc
     4381 tccaagttga actcgcgcaa cgcatttgtg tactcaggga tctggaacag gccggtgatg
     4441 aactcgatct cgacgatgag caacttcgac gccacgctct ccatcgtcag gaacgtcgtg
     4501 aatgcctcca agacgtcaaa ttggtggtac cacccaggtt tctcgctggc ttcttgaagc
     4561 tcggtgaggt tgtccagttc atcgcgggtg acgtcataga tggacccgaa agcgagaatg
     4621 tcggcatacc tgaacgactg aacgcgtccg gcctcgatcg ctttgagctt gctggctttg
     4681 gcgatcttga cgacctcagc gtctcctggt ttgagcccgg cacggagccg gtactccttg
     4741 aggaaccgac caagttgaat cttcgcgaga tttgggttca ggttgctact catagtcaca
     4801 tggtctcata catgacccct cccatggagt tggtcgtttt ttgaccggtt ttttacgacc
     4861 ggttattcat ggccccgttt cgcacctagt caattactga ctgttccttt agcgtcgatt
     4921 ctatcggtgg gttcaatcac acaccgagtc gcatcacagc aggacgcccc gccggtgggg
     4981 acggggcgtc cgtgagatcg aggagctgac ggccatgacc aaacaatcga cggcaccgac
     5041 gccgagatcg tcgggtccgg tcacgattcc atgtcgaagc caagactgca agaacggttt
     5101 cgtggccaag gaagtcgacg gtcaacttcg cgcggagatg tgcgaaagct gtgacggcac
     5161 cggcaacaag accgtcgtcg cgaaagagtg cgacggatga gcgcgccgat gcgggcggct
     5221 tcactccacg ggcgggcgct tgttgtactt gttcatcgtg gacttgttag tcgaagcgtc
     5281 ctggaagatc aacgcccatg gtccactgtt gacttccatt tccttgccga agccgagcca
     5341 ttttccactg atcttgcggc cggttggttc ggcgatcatc tggatcgcac cgtggtaccg
     5401 ggctccccgg tagtacccgt ccttgtgggt ctgctccacc caggttcccg tcacaacgga
     5461 accgtccacg gtgaggtcca tcgtcagcgg cgagtcggag gatccgggga ggctgcgggc
     5521 ggtcagtcgg tcgccgtgtt gcagcaccag gacgtagtgg acgccgatga aggtgtcgcc
     5581 gcgcccggag gagtagtact cgtaacgcga cagccagatg cccgaatagt tcgtcgaggt
     5641 cgcgttcttg ccggcatgcg caacgggcgc gatgacctcg aagtcgggcc cgctcgcggc
     5701 tacgtcgtgt cccccttgac cgttgggggt cacccgagcg gccggaaccg gtacagcgaa
     5761 tccgagctcg gtgatcggca ggccggtcac ggattcgagc gctcgggcat agaccggacg
     5821 tggcgacgcg ctctcgccgg attcccatcg ctgcaccagg cgtttcgacg cgtcgttggg
     5881 gactcccgcg cgctgtccgg cttcccggag cgcacgcgcg aattcgtctt gagacagcag
     5941 cagccccttc cggattgctt gcaacgtcga gttcgtcatg cgctccacgt taccaccgtc
     6001 aacgtcaccg aaatgacgcc ttttatgtcg ccggaacgac gcctcaaacg tcgtcgcgga
     6061 cagctacaga gtcgcgtcac agtgtcgaca gttccctatt ccgcgcgacc ggcgaaagag
     6121 gcggtccaat gaggtcccac cagtccccga tcgagcccga accggtattg ccagaggttc
     6181 agttcgatgc cgcccccagt ccggaggcgc ccctcatcgc cccatgtgga ttcccggtgg
     6241 aggcggtacg cctgtccccg gaccagtacg tcatggtctg tggccccgag tgcggcgatc
     6301 accaatggcc gatcccacag cagcgccgcg ccgaaacctc gtcgcagccc gcactcgtgg
     6361 ccgcgcttcg gaccagggca ccgcagcgcg gccacccaca cccagacacc gaacaggaga
     6421 aacctcatgc tcgcagcacc cgtacctgct agacatgccg ccgcgaccca accgccgcgc
     6481 aacatgtgga ggttcaaact cgttcgatac gaggacgtct ccggcgtgtc agggaccggg
     6541 gttgtcgcgg tcggggtcgt ctgctcggac ggcagcgcgt ggatgcgctg ggactcttcg
     6601 gatccttcca gcgccatgtt cgacaactgg cgaacgatcg aacgcaagca cggccatcgt
     6661 ggggcgaccg agctccagtg gattgatatg ccccccaaca cgttcctcca ccacgagacc
     6721 tgacctcctc ttcccccggg gccgccgcgt tcggacagcc aaccgacgag cgcggcggcc
     6781 accacacaac aagccgccca ccacgacacc gacaggaggg ttcgggtgtt cttctcccat
     6841 cgatcgaccc gacatcatcg actccccgcg atgtatgacg agctgacgct tcccagcgac
     6901 tacgtcttgt accagcgggt gtcgcttctg tcggacattg cggtgatggt cgagtgcggc
     6961 cacccgatcg actgtgcttt cgacgggagg cacttctact accactgcac cggcacggag
     7021 ccaaccggcg ccgaccgtat cgagtggtac tgcggacgac accgactggg ctacgccgat
     7081 gacatcgacc gagcggtatg gacgcagaca ttccggctcc tgcccaaggc ccgccgagca
     7141 cgcaccgcct accaacgacg gtcgctcctg ctggctacgc acgctctggt gaaggtgagc
     7201 ctcagcgacc cgcgatgccc cgtcgtcgag tggatcggac acaagcgact cggcgaccgc
     7261 agcttccaca ccgaccatga ccgcgccctc gcgcaccgac tcaaggaccg gcgcgtcgag
     7321 gccgccgcca gccgtcaccc actacgccgt gcggcaaaca gcttggtgaa tcccttcgag
     7381 atgtaaagga aacccatcca tgacaactgt caacgcacct gtccctacat acgccttggc
     7441 caaacgtcag ccggccgcca ccgaccccaa ggtgtggaca cggctcggtg tccacatcac
     7501 cgacctgcac aacgaggctc agggactgcg ccgccccgaa cgactaacgc gggcggccct
     7561 cggcgccgtc acgctgctgc gctcgctcgg tgtccgcatt gaactgccca gcggagaatt
     7621 gccgacacgg gatctgccca gcgcactgtc gcggccgaaa ccctcaggga cgttgacgct
     7681 gaccgaccgc gaacgtgaag tgctcggtgg catggccgaa ggcaagagca acgccgagat
     7741 cggacgcgaa ctgttcgtca ccgaggacac catcaagacc cacgcgcggc ggctgtttcg
     7801 caagctcgac gcccgcgacc gcgcccacgc cgtcagccag ggcttccgtc tggagctgct
     7861 gacatgaacg gcatcgccgt cctggccgtc atcctgttcg tcgtcatcgg cgggccgagc
     7921 tggattctca gcatcttcag tcccgcctac cgcaagcgac gccgcgagtc gcgcgcgaag
     7981 accgcgaaca aggcatgggg cctgctcgcc ctcgcgggga cgatcgcgtt gatcggcctg
     8041 gccggtttgg actacatcgg actcatcgag atcaagtaaa cacaatggag gcgaaagtct
     8101 tgggacgcat cgtatggcgc ggctaccgct ggtgcgggca caccgacatg ctgcgccgat
     8161 cccgggactt cccgccattg caccctcgac actggacccg cttctccgcg acatgcatcg
     8221 ggcaatgggc cgacgaacgc cgggcactgg attggttgtg gaaccagatg gccgaagcac
     8281 acgaccatat cgttgccgag ttcccgcagc gcgctgtcgc gatccgaagc gagtacgacg
     8341 acgccgcgca gcgcttgtgc gacagcgacg actgtgcctg ttcctggtcg attgccctcc
     8401 ccgcctcgat ccgtctgtac gtcggcatcg tcgccgtcta cgaacatcct tcaaccatcc
     8461 agggggacac gtgaggctgg ttgtctcaga cacgccgaca tcgcggggtg gccgcttacg
     8521 gtcgctcgcg cacgatgaac cgataacacc aaccgcaacg agaaggggaa gtccaatttc
     8581 tactgtcaat gtcaccgagg atgccgcgca gatgcgcaac gcgatggtcg acggcatcgt
     8641 caagtgggcg aaactgtcgg acgcgaccgc ggcggcaatg cgcaaagtcg agcggcaccg
     8701 attcgttccg gccgccacgc ttaaagaggc gtacaccgac gacacggtgg tgacgcgtcg
     8761 cgacgaggcc gggatcgcca ctagctcggc gtccgcgccg tggctgcaag ggatgatgct
     8821 cgaccagctt gagctgcggc ccggcatgac ggtgctggag atcggggccg ggaccggcgt
     8881 caacgctggc tacgtgaccg aattggtcgg gcccagcggt cacgtcacca ccatcgatat
     8941 tcagcctgat gtcgccgaag acgcccgcac cgcgctcgcg ctcaccgggg ctacgaacgt
     9001 cgaggtcatc tgcggcgacg gcgaatacgg atatcccgcg aacgctccgt acgaccgggt
     9061 catcgctacg gccggggcct gggacatccc ggagcactgg gtcgagcagc tcaaaccgga
     9121 cgggctcatg gtcgtcccgc tgcgcatgaa cggcttgacc cgttcggtcg cgttcacccg
     9181 ggacgaacac ggcgtgtggc actcgaagag cgcggtcaac tgcgggttca tgccagtcag
     9241 gggcgacggc gaagtcatcg agaccaacgt ccagatcgcc aaggacgtgg tggtccgtat
     9301 cgatgacggt caagacctcg acgtcgaagc gctcaaggac gcgattgccg attccgggga
     9361 agtcgaatgg acgggcattc tcatcgacgc gccactagac ctgctggact tttacatggc
     9421 cgatatggac ggtttctgcc gcatcctggc cccaccgtcc atcgccgagc gcgggctggc
     9481 cgaacccatg aacggctggg gaagcatggg cgccgcgacc ccggacgcgg tggggtactt
     9541 gacgaagcgt tacggcccgc tgcacccgaa gctgtacgaa ctgggcacct gcgcgtacgg
     9601 gccgcaagcg caagccatgg tcgatgagct gaccaaacgg gtctacgcct gggaccgggc
     9661 gcgcaagtcg gtcaccggcg tccacattga gatccaccca tcggggcaag gcgacaccgc
     9721 cgacgcgctc atgaccatcg acaagcggca ctcccgggtc atcgtccgac ccgcgtaaaa
     9781 gctgagctct gcctcagaac ctcaggaaat cccaaccaca acgataggag aacaccatga
     9841 agcccactct cgaagccaca acggacatcg aagcctttga ggacctgttc aaactcgacg
     9901 tacgcatcga ggccgagggc ccgagcttga gccgctgcaa cccgaccaac gacggctgct
     9961 ccaactcctg cacgtccgtc ggatgctcgg ccaactgctg atgaccagcc acagcacgcg
    10021 acgcgggacg gcattcacta cgccgttccg cgtcgcggat ccccggtccg ggctggcccg
    10081 gcttccgctg ttgcacaacg atcccagccc gaacacctcg atagatcctg tcgtggccga
    10141 ggggatgttc ctttgctccg agatccacgc cgatgtctcc cccgacagcg ccgagcagcg
    10201 ccgcgccacc gaacgggcat ttgacatccg cgcacggcga cgcaccaccc cgcaaggcgt
    10261 gttcgcgggc gtcaccgaac tggacatcaa cgtcgcggcg tcgaccctgt ccgtccgcac
    10321 cgagcacaaa gtccggtcgt accccaatcc cgtgtgggtc catgagatcg gtgatcgcgt
    10381 gctggacagc gccgccgtgt tgcacgcgct gacctatacg accaacaatc tcgcggcgcg
    10441 gcgcggtgac cgcctggatg tccaacgccc ctccagcgac ccgcgaaccg gaccgcagcg
    10501 catgagcgtt cgccgcaccg aggccgtcga agtcgtcctg gacgtcgctc ggtccggtgc
    10561 gtcgtggaag cagatcacca ccgcgctgac acaacggtgg ccgagcatcc aggacaccac
    10621 ggttgaggtg gtcatgcggc agctgacccg cagcggtttc ttgttgaccg acctggatcc
    10681 cgtcgatacc tgcactgacc cgctcggtca cctcctggcc aaactcccgg cgtccgaacc
    10741 ggtacgcgaa ccgctgtcgt ggctgcgcgc cgcgctggcc gaagccgatg cacacccgcc
    10801 cggccaccca gcacgtatgg ccgcgctcaa gaccgcgcgc aatatcgccg acgacctgtt
    10861 cgcgacctgg cgacccatct gcaccgacac cgcgatgaac gcccacatct ccatcccggc
    10921 acgcgtggcc gaagaggccg ctcaagccgc caacgtcttg tggcgcatgc cgcctcggca
    10981 tgatccgctg gccgaatggc acgaacgctt cctccaccgc tacggcaccg gccgtctcgt
    11041 gcccctgctg gaggtgtgcg accccgtcac cggattgggt tgcgaccccg gcaacaccga
    11101 agtagtgccc cctccggaat ccactgaagc cttggcccgg ctgatcaacg ttgcgttgac
    11161 ctccaacaag atggaggtac agctggacgc ggcaacgatc accgcgctcg accagcgccg
    11221 ccccagtgac gcttgcgaac cttcggctga gctgtacgcg acggtcgttg cccgtgacga
    11281 acacgaccgc gacgccggga agttcgtcct ggccgtcacc aacatggctt caccggccgg
    11341 gtcaactcgc gcccggttcg ccggcctgct ccccgacgcc tccgttgcga gcgacccagg
    11401 gcacggcacc atgaccgccg aactggcatt ccggcccacg tcccacaccg tcgcggcgct
    11461 gaccggccgc gcggacaacg cgccgtggcg catcccgatc ggcacgatcc cccagtccgg
    11521 cgacctcgcg ctggacgacc tcgctgtggt ctctgacggc gcccgcctga ggctttggtc
    11581 cacacagaac aaccggccgg ttcggcccgt ccaccacaac caggtaggcc accacctgat
    11641 gccacccgtg gccgcgttct tgtgcctgct gggccagcac ggcaacaccg ggttgagccc
    11701 gtggacatgg ggaccattcg agcgtgcccc cttcacccca cgggtgcgct tccgcgacgt
    11761 catcctgtcc ccggcccgct ggcgactccc cgaagaggtc cgagacgccg ccaccgaccg
    11821 gtcgacatgg gccacggcac tgcgacgctg gcgcaccagc gcccggcccg ctccaccggc
    11881 caccgtcgtc atcgacacca gcgaccgaaa acttcccctt gacctcgatc gtggcgacga
    11941 ccgcgaactc ctgcgccgct acgtcaaccg agacgtgacc gcggtgaccg aaccgcctgg
    12001 cggccccgac gcggttcagg ccgtggccct cggagaaaga gggcaccacg tcttggagat
    12061 tgtcgtgccg gtctccgctt cgcacaccga ggagaccgca ccaccggcgc cggcgctggc
    12121 acgccaatcc agacacagcg tgttcacgcc ggggagcgaa tggctgtcgc tggccatcga
    12181 tgctccaccg tcgactcaag acgccgtgct ggctcgcctc gccgacgccg cgcaccacgc
    12241 gaccgggctg tggcaccgat ggttctggat tcgctaccac actcccgcgc gcggacccca
    12301 ccttcgagtc cggttccgcg gcgacccgag gcccctgggc gggcaactac tcccgctgtt
    12361 gggcgacacc tgtgcgaacc tgaccactga tggtctgtcc ggtggattcg ggatcgagga
    12421 gtaccgccaa gagatcgaac gctacggcgg cgagcacgcg atcgaatacg tcgaagacac
    12481 cttccaccac gacgccaacc ttgtcgcaca tctcctggcc gaaagctccg acccggatga
    12541 gcgcctggcg ttgaccgccg cctcggccgc cgagatcgtc cgcatcgtcg ccgacgggaa
    12601 ccgcgcggct ctggttccgc accgtctgga gagggcagac cgtcgcaccc atgcccgtgt
    12661 ccggcctcgc gcccgctcca tcgatgacgg cacgcccgct catcggccac tgtggtatga
    12721 gcgcaccgct gccctgacgg cataccgcgc ggtcctgcca ccggaccgcc gcatcgactg
    12781 cgcttcatcg ctgattcata tgcacgccaa ccgtctcctg ggcgacaacc atcgtgagcg
    12841 catcgcacgc gcactcgccg tagatctcat cgcgcgggag gccccatgac caccatcgag
    12901 gaacaagttc tgacggttgc cgatcggctt cttaaacccg aagcggtcct caacgcggta
    12961 ggcagagccg atgcggcttc gctgactcgt ggattggcgg ggaccgcgct gctgcacgcc
    13021 cgcctcgcgc acattgatcc gcgcttcgct cgcgctgccc agcagcactg gactgccgcc
    13081 gccgctcacc ttaaaaatca ccgacacggg ttcagcggta tcgctggcgg gcaaggcggc
    13141 ctggctgctt ccctcatcat cggcaccggc tacctccccg aaggcaaccg tcaccacgct
    13201 gccgctgcgg gtgcttcctg gctggctgtg tgcgcccgcg atgcggccga cctgtaccag
    13261 cgcaccgacc tactcacctg ggacgtctac gatgcgatca ccggcctatc aggaatcggg
    13321 cgcgtactgc tggcggctca aagctcggga tacgacgacg tcgaatcggg ccttatggca
    13381 gcgctgacgg cgctgaccgc gatcctcgaa ccccgcgaca ccggacgtcc aggatggtgg
    13441 atgcctgccg agaaccatcc gaatctcgca cgaatccacc cgtcgggagc agcaaccacc
    13501 ggcctggccc acggcgtcgc cggtcccctg gctctccttg ccaccgcaca cgtcgccgga
    13561 tggtccgtac ccggccaggc cgaagggatc gaccacgccg ccgactggct cctggactgg
    13621 cgccgagatg acggcacctg gccgccgtcg gtcactggcg acgaactcga caccgcccaa
    13681 ccaccgtcga ctccgggccg cgccgacgca tggtgctacg gcacccccgg catcagccgc
    13741 tccctacacc tcgccgggct cgcactcgac gacccacacc tacaggctgc cgcgatctcc
    13801 gcggtggaca ccatgggttc ccggaaacca gccgagtggg acgtggaggg accgacgctg
    13861 tgccacggtt acgccgggtt ccttcaatcg gctcccgaca accaccctgt tgccggggcc
    13921 gtcgtcgaag ccatcagcgc ttacttcgac tcgagccacc gattcggatt ccagcatcgc
    13981 gaccagggcc aaacccacgt tgaacccggc ctcttgaccg gcgcggccgg tgtcgccctc
    14041 gcgctggccg aacaccaaga cctccccaca ccaggcaccc cagccagctg ggaatgcctg
    14101 ctcaacctgt cataaccaac accgaaggag gcaccaacct tgtccgaacc caccactgca
    14161 accgaaccgt ccgcgccgac tcccaagtcc gacggaggcc aggccggcga cctgtgccgc
    14221 aggattctgg cggtccacga tcgggtcagc acggccagca cggacctcaa tcgcctgttc
    14281 gcccagaccg ccattgagct gtctggcctg ttggccgacg gctaccagct ccaccacaaa
    14341 acgctcactg cgggcttcga cgatgccgcc ttccagctcc accacatgct cgtcgcgctg
    14401 tccaacgtcc aaatcgacgt ctccaccgtc accgacaccg cagcgaagct ccccactttg
    14461 accaaagcct tcgcgcacga acggcacatc gacctcaacg cgacaccacc cgacgaaccc
    14521 gcaccgtagg ttggcgatat gaccacgttt gaacagctcg tcgctgccgt gaacaacgcg
    14581 gtcgccgaag tgggcgaagc tcgaacttta gcggctcaag gcatccagca cgtcgcgcgg
    14641 tcgtcgaccc ggatggagaa cattgcctgc ggctcctcct cctaccggct gcgtgacgtg
    14701 ctggccgcac tgactgccgc catcacggcg atcgagcaca gcaacacggc agcagcatcc
    14761 gcctcggccc agctcaatac atacctggcg gcgatcggca actcgaccac aaccgttgag
    14821 gctcaaccag aagcagcacc accgccagca gccgccgaga gcctcgacag caccccacgt
    14881 ctcccagatg gcggcatcga cttccacgcg ctcgccaagc ggctcgggct tctcgaagcc
    14941 cgtccgacgg agcagccgcc gttcgacccc cggcgattca acccggcctg ctggcaaggg
    15001 ctcaaaccct acgaccaggc cggaaccgcc gaggggaacc tgttcatcgc gcccggcaag
    15061 cgatggaaca cccgcccgat gcaggccagc aagctcgaag tcggacccca aagcgatctt
    15121 cacccgcagt ggcgatcccg aaaagctccc tggcacatcg aaggcaagat tgccgcgtac
    15181 atgcggcaga agggattcac cgacgggtgc gtctacctca atgctcgccc ctgttctgga
    15241 ccagacggct gcgcgcgaaa cctccccgac ttgctgcctg tgggatctac gctgcacgta
    15301 cacgcccgat acatcgaccg caccggcgag acccgtttct attacaggga gtatcgggga
    15361 accggaaagg cactgacttg accgacacct atgacctgca tcctgagccc gaagagttcg
    15421 acgacattcc cgtcaccgat gatcccgaac tcaatcggga gctgctgcgc gccgtcctgg
    15481 acggtaccga ccccgcccag atcatgcagc gcgtcagcaa ggcaggcatc gtcccgcctg
    15541 aaccgggccg agacgactgg gccttcgcga tcatccacga gggcaaccca gaaaccggca
    15601 ctgtcatctg ggattgagcc tggctctccc acgcttgaca cgccactaag gatcatcctt
    15661 actggcatct ggagtagatc caagacgtcg ctgcaaaaga ctcaacgcgt ccttcgcgga
    15721 aggcgattct gtagccacaa cctcgaaggc agtgaggaag tcgcgggcac tctggttgag
    15781 tttctgggcc gcggtctcgg catggtcatc aatgtgagtg atggcccatc gaacacgcga
    15841 ctgccagtcg acatcctcgg gctcgcggcc aggcaggggc aggtcggccg cggcttcggc
    15901 gaaggcgccg gcgtcagctc ccggaagtgg tgcggtgccg gttgaccatg cggcgaaccg
    15961 attcggcgac acgggcaccg ctggagtcgc gtggatggtg gcgtcgggat cgtcgggaac
    16021 gagcaacgac atgaagggca caccgagcgc cgccgccaac gtcacggtta catccagtga
    16081 aagcttgcgc ctgccggact cgatgttcca gatgatgttg tcggtgacgt ccgtggcacc
    16141 aagccggcgg catcgctcca cgacgtcgtc gacggtgagg ccgagtcgat cgcgcagctg
    16201 tcgcaggcga tgccgcgcga cgctgctggg cggagtatga ccttcgcctt caattcctgt
    16261 catatcgaca gatcctagag gattcgttga cgatttacct gcggttttgc aggattgctt
    16321 ccatcagtac gacagcttgt ctgtcgattc gacaggaagg aaacgacaat gtcaaccaca
    16381 cgaatccccc ggaaagctct ggtgtggaca cgggaacgag tgctcagtct cggatcaacg
    16441 acaaccgtgg agacggcggg cgcggtcctg ggcattggcc gaacactggc ataccaactc
    16501 gcggccaacg gcaacttccc ggtgacggtc tttcgcgcag ggcacctgta ccgagtaccg
    16561 gtcggccccc tggtagctct gctgtggccg gacgcgacac cggcttcaaa cgacgtgaat
    16621 ggtgggggcg agtgatgacg tacgacgatg cgcaccaccc cgcagcggcc gaggcgctgg
    16681 aagagtactg ccagcacgca atcgaaacca tgaccacgca cggcggcatg atgcccgctc
    16741 cgaccgtcta catgttctcc ggggacggtg agcacctcga cagccttcag ggatacgtca
    16801 tcgcgcggcc gtcgcattcg ggcggagacg ccggcgacgc gatacgccag ctcgggctat
    16861 tgccgggggt gctgcgctgc gatcggatcg tcatcgcctg ggaacaccga acgaccgcga
    16921 cgctgctggg ccgcggaggc gatcatcaaa ccgggatcgc cgctgtcgaa gcggcgcggg
    16981 accatcgcgt tgtcacgtgg cgaccattca ccgtccatca tggcgattac ggcatccacg
    17041 ggaccaggtc gatgatcgcc acgtggggcc gagcccaaga actacgaacg cgcctgcctg
    17101 tgccgatcgc cgacgcggtt cgagtatgga cgaatgcctc ctgcgcatcg attacctcca
    17161 ctgtggcaaa actcgaagct gcggggtacc tcgtgtcgct gttccacgag ggatggtgag
    17221 gagaatgcac ttcggaacga cggacggatc caacacttcg ccgaacgtgc gcgtgggcaa
    17281 ccggtcgatg agtctggacg acttgtaccg cgaccgcgca cgatgcgcgc gcatcctggc
    17341 gagcgcaaga gccgaagacg ggcacgcctg gtgcgaatgc aactgcccac aatcgaaact
    17401 ggtcatccga tgccgccaag gcgtctggca cctggctcgg tggcccggcg accgaatcgg
    17461 ccatgcggca aattgtccct tccgaggcat agaccccggg ttgaccggcc gcgctgcctt
    17521 cagcgaatcc gcgatccagg aatcacgcga tggggtccat ctcaggatcg ccaccagctt
    17581 gacgacggat cttggtaccc gaagtaagcc ggggctcggt gaccatcacc gtggtggtgg
    17641 ttcgaatcga caccgtctga cgctgctggg actactggaa tatctctggg aggaaagccg
    17701 cctcaacgaa taccggagtg ggtcacggct atggtgggga aggtgccacc acgcgctcgt
    17761 aagccaagtg gaaaacagct tcctcggcga ccagcctttg agcgaagtga tgtatgtggt
    17821 tccgccgttt cggaaagaaa gcgcggccaa taacgaagcc acatggaacg catttgcggc
    17881 gggacttggt tcaaagaatc gtcgctcgcg cctggggatc gtcctaggtg aattcaagga
    17941 cgcggcggcg acttcacgcg ggtaccggat tcgactgcgc aacttccgaa agcccatatt
    18001 cgtgacgcga aaactgtggg acacactcac catgaggttt caatctgcgt tcacctctca
    18061 gatgactgca cagggcaggc aagttggctt gtgggttgtc gacaaggcga cgcgagggta
    18121 tctgcgattg tcaacagctg gcatcatggc gacgacacag tcatggatcc ctgtagattc
    18181 gggatacgaa ttgacgatgg ccaatgcact tgccgatgcc aaccggagct tcctgaaacc
    18241 attgcgatat cagcattgtg acgtggtact gccagacttc gttattaccg acaccaaccc
    18301 aagaacatat attgaagttt ggggaatcgt cggtcgagag tcttacgaac gacgtaaaca
    18361 ggagaagcag gactactaca aacagcgcgg actccagctc atcgagtgga acgtttctga
    18421 atcgatccca gaagtaccgc gactgttatc gtgtagggtc tcatcgaggt tgagcaccga
    18481 ggacgccgtg accagtagct cgggtcaatt tgtcgccggt ttgagcagct cggattctca
    18541 cgggaatgag caattccctc aggccacccc agcgttgtga ctgcgtcgcc gtcagttctg
    18601 actggctgcc aagcctgagc gcgttgaaat gtaactgcgt tgagcccgct gaccaccagc
    18661 caccgagatt ggcgaccgtc aggttggcgg cgttctttcg atttcgctct ctggccggga
    18721 actcttgccc gggaacgagt cgaggtaggt atgttgcgca ccgtagagcc ggagctgttc
    18781 ggtcatgtcc tgggctgccg cgtcatgcct cattgctacg ccccggcgcg tggcgtccca
    18841 gtcgacagga ggattccttg accacgattt gttcagcaga tccttcattt cggattggca
    18901 ttcctgagcg gtatggatga aactgaagac agattgggtg ggcgcgaagc tctctgctct
    18961 gaccgcggcg atgagatact ccttgtcgag ggaactgatg ttccgccgca tggtggggat
    19021 gtcgtccgta agccccgccc cctcctcgcc tccgggcgtg ttcggaacgc tggcgagctc
    19081 aacgatgtac tcctgtgtga ccgtgaggta atggagtgag atcccgacga agtcgatgca
    19141 cgcatcgagg gagcgtccgc tggctcgttc cttggcgccg gaccggtgga ggctccggtt
    19201 ggtcaggaac gcgaccaccg cgccgaggag tcatcctaca agagtgaaga caccggtcgc
    19261 gatgacaagt tgtagtttcg cgctcatgct gctgattctc ccaagaagtc ctcgtggcca
    19321 ctgctgaacc catgaggtca cgagtcggtt gtttaccttc cttgcattca agcctcgcct
    19381 cgttccgtca acactgtctg cccggaactc aagtcggcaa ccttgaaccg ggatggatat
    19441 gacctgaccc gacatcatga actggcgcta tgtcacaggg acctgcgaaa atcgggttct
    19501 actcgggacc gcacacacca acaaggagag ccatgcaaaa gaacaatggc caccgcatcg
    19561 aggtgccccc atacattgct gaacagataa gcaagttcgc gaaacagaac cggctcagcc
    19621 gaaacgaagc ggtcgaggag atcttcgctg ctggactcga agccctaggc gccaacccca
    19681 ccgacttctc gggcaacggc ccctactggc tggaatccac ctccgtccga cacaacgccg
    19741 acggcgaacc cgaacttgac ccgagctggg ttccaaccga gtcggcattg acgcttgaag
    19801 atgctcgacg acaacttgtc taccacgtaa tacgcggctc aaaggaccac atgtcctatc
    19861 aaggccacgg cgaactgctc gaatccacgc cgctaggtct tccggtcaaa tacgacaacc
    19921 agtactggag aattgtcaag cgcaccaaac caacgcctca actctgataa ccccctcgct
    19981 ccgtcgttgg cgacgtgatc gacgagcgct gccgtctacc cgacagattc tcacccgatt
    20041 gagcaactgc tcagatcggc gataattgct taagggaaat gagaacctac atatcgagtt
    20101 aactgacaga aattccgcga tccttcaggt atttcctggg gtcgatcgcg tttccagggt
    20161 ctgccggata gtcgccgtgc gcctcgaagt ggaggtgtgg gccgctggag tttcctgagt
    20221 tgccgacctt tccgagcttc tggccagcgt tgaccttttg gccttcgttg accgatgggc
    20281 gggaaaccat gtggcagtaa cgggtgacgg tcttgtcggc gtgttggatc tcgacgtacc
    20341 agccgcaccc catgatgtgg actcctccgt cgatgttgca gctgtatggt tgcccggctc
    20401 ccgtggatgc gttgcacgta acggtcttga cggttccggc tccgacggcc ttgatggtgg
    20461 ttccgcgggc ggcgccgaag tcaatgccgt gatggtcggg gcgttccgag gtccgatatc
    20521 cggagacgat cccagcgttc actggtttcg cccatttgcc tgatccggtg ccggcggcgc
    20581 agattcgcgg attctccagc gtgttcacga tcttcttggc cttgggttcg tgtttcgcgt
    20641 aggcgtcggg gaatgctgag ccctgcacgg tttgggccgc gacggtcaac ggaagggact
    20701 gccagccgct caccttcttc aacgaatcga agaatttgcc cgcggcgtac ttcgggttcg
    20761 tgatctgagt gggcgagccc cagccagccg aggggcgctg ttgaaacagg ccgagggagt
    20821 cgtggtcgtt gcggtcgccg aggtggccgt agttgtggag ggtgctttcc tgaatggcgg
    20881 tggcgatgcc gatgatggct gcgcggcggc ccatgctctt gtcgagcgcg acttcgtaga
    20941 tggtggcggc gtggcccaat tgggtcttgc tgagtcccag ggcggtggct gtcttcttcg
    21001 tgatcgaaca ggtcacgcca ccggattctg ccgcgtcgtc ggttgaaacg gcgacgatgg
    21061 ctagggcgac gacagctacg aggggcagaa ccatcaccgc cgcaatagcg aggccgattt
    21121 tgagagtgag ggggtgagac tcagacatgg aggcgccttc gagggttgac gaaacgcggc
    21181 ggcaggggcc ggacgtcatg gtgagtgtcc gtcacccggc aacacgtgat cttttactgt
    21241 ggtaaagatt tcggtgggtg acgaaggtta cgccctaggt tcgcttaggt gtcaagtagc
    21301 gttgcgaact tgttaccaag tgtcatttct tggccgcggt gaggcggggg taggtctgtg
    21361 ccaggtggtc ggccaggtgc gtggcggcct tttcctggta gctggtgtag gtgatcgtct
    21421 gcgggatttc gctgtgggtg atggtgtgcc cgaggatgac gtgggcgagg tcgtgcagca
    21481 agcatgtcgg cgtggccacg gcagtgacga cgagatgatc ggcaacgtcg gtggcgatcc
    21541 acacgccgtg ccgagtgggg ggcagccgga cggtcattcg gcgaatctcg aatacgcgtc
    21601 ctcggattcg cgagatagcc gcgacaagat catcaaggcc ggcattaggc ggcaggccca
    21661 gtcgctgagt cacggcgtca gcgtctggca aggcggtgga cataactccc ccaaggaggg
    21721 tcgtcgaccg gtaacggtcg gtgcgttccg ccaggataat caggggatgc aaaggcgacc
    21781 gctgcgttgt cgcctgcgtc ggtggggtca agtcgcgggg ttttcagatg atgaaacatc
    21841 tgggtcattc cccgcgtttt cggatcgcgg tgccttggct tcgatgggtg gaagtccttc
    21901 cgcggcgcgg gccttggcga tcatcagctg aatcagttcg acggattcgg gcgacagccc
    21961 ggaggcgtgg tgggcgatgg cgcggacgcg ttcggcgttg gcaatctcca tgaccgcggc
    22021 gacttcgttg tcctgatagt cggggtcggg gccgctgaag tactcggtgg tgaccccgaa
    22081 gtagtccgcc agagcctgaa gtaggcggta gctggggtcg tcgcgttggt cgcgtcgcag
    22141 tagagacagg tagccgtggg aaaccttgac tccggcgttg gtcaaatcgt cggcgacctt
    22201 cgagttcgac acaccctggt tgacgaacag ggcgtccagg cggcgcgcga gccgcccccg
    22261 ccctgaatgg gcgtcgtcgt ggtcgctgtt gctggagtgg ttcctggggt cgttcattct
    22321 tcagtttgcc ctgtctgtcg gcttgtgcca gctagtatca ccgtttgcaa cgggaacgtc
    22381 accaaatgtc tcaagttgat aacgctctac gcctgcggcg gacatcaccg gttgtcgtca
    22441 tgtgattgcg gtcctagtgt ggccggacac tgtccaccct tcgactgtag tcgaagctcc
    22501 tgagtacggg agaccccaca tgtccacgac aatgcacgtc atcaacgcaa gctccgacgc
    22561 cctggccgcg ctggctggcc tggccgatct cggcgacatt cccaatccga aaccgaaaga
    22621 ccccacgggc ggtagcaagg ggctcaacca gctcatcagc tactcgaaat ggggcgtact
    22681 catcacctgc gcgatctgcg cggttgcctc gggcgccttc atggccgcgg gcagcatgag
    22741 caaccggccc aacgccgtcg acaaaggcaa ggtctctctg ctgtggagct tggcgggtgt
    22801 gatcgtgtcg gcgatggcga tcccggtcgt caactcggtc ttcggcgcag cgtcctaatc
    22861 gcactgatga aatcacggga gatgccatgt cgcagtcaga attcttcgcc aagcccccgc
    22921 gccgcggacg cattgtcgta gccgtcatca cggggctggt gttggtggcc gccgggataa
    22981 ccgtcggagt catcgtcacc ggagacgact ccagccagac cgaaaccgca tcgcctggct
    23041 cctcggccag cccatcggcg tcaaccgacg gtgccgaatc gtcactgccg attgtggcgg
    23101 gcgaggacac cgaagccggt gtcggcgtcg gctatccgca cagcaaggtc ggcgcggtat
    23161 ccgcggccgt ggagttcacc tcgcaggtgc tttccaccct ggaccctgac cgggcggttg
    23221 aagtcgctga ggtcgccaac gaccccgata acgggttcga tcccgccgat gcggccaaca
    23281 ccgtgaccgc gatgcgcgaa cagatggggc tgcctcctac cggggacgtc cctgagggag
    23341 cgtccatcgt gacggcaccc gttgcctacc agctgcgtga cgaaaccacc gacagcatgg
    23401 tggtgctgtt gctgtgttac gtcaccaaag acaccggaag cggggaacct caggaagacg
    23461 tcggcgtgtt cacgatgccg atggcctgga acggcgacga ctggaagttg gtgcgatcag
    23521 acgacgacac cgactacacc gatctgaaca ccacaccggg tagcgatgaa gctcgcgcga
    23581 agggctggat cggggtaacc cgatgagtgc cttctgcaac ccgttctcca cgaaccccgc
    23641 cgatatcgcc gagtgtgtcg cagagggaca gaaagccggc ggggcgatcg acgcggctct
    23701 caatcccttc gaagccatct gccaagcgtt cgccgaggcc gcggccgaca tgctcaaaga
    23761 gttcgccaag gcgttcgcga agttcccgaa catcgatgtg accgatcccg gtgtcaccga
    23821 cgtctattcg ctgtcgatgg gtatcggcat cttcgccgcg gtgatcctcc tgctgctcca
    23881 aaccgcgcga acggccatca cccacgaagg caaagccctg gccgaagggc tcgtcggcgt
    23941 cggcaaagcc gcactggcga tgatgctgac gctcagcttg acgaccgccg ggctattggc
    24001 cgccgacgaa ctgacaaagt ggatcatcaa ggaatccttc ggctcggtgg agaagctgac
    24061 caaacgcctg tcgagtttct tggtaatcga gaccgtcgcc aaccttccac aaatg
//
