LOCUS       NC_013729              12936 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Kribbella flavida DSM 17836, complete sequence.
ACCESSION   NC_013729
VERSION     NC_013729.1
KEYWORDS    RefSeq.
SOURCE      Kribbella flavida DSM 17836
  ORGANISM  Kribbella flavida DSM 17836
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 7579488)
  AUTHORS   Pukall,R., Lapidus,A., Glavina Del Rio,T., Copeland,A., Tice,H.,
            Cheng,J.F., Lucas,S., Chen,F., Nolan,M., Labutti,K., Pati,A.,
            Ivanova,N., Mavromatis,K., Mikhailova,N., Pitluck,S., Bruce,D.,
            Goodwin,L., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D., Chen,A.,
            Palaniappan,K., Chain,P., Rohde,M., Goker,M., Bristow,J.,
            Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C., Klenk,H.P.
            and Brettin,T.
  TITLE     Complete genome sequence of Kribbella flavida type strain (IFO
            14399)
  JOURNAL   Stand Genomic Sci 2 (2), 186-193 (2010)
   PUBMED   21304701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Kribbella flavida DSM 17836
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024345.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,131
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 7,033
            CDSs (with protein)               :: 7,033
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 8 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 4 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name             :: Kribbella flavida DSM 17836
            Culture Collection ID :: DSM 17836, JCM 10339, KCTC 9580, NBRC 14399
            GOLD Stamp ID                     :: Gi02235
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: GeneMark
            Isolation Site                    :: Soil from China
            Isolation Country                 :: China
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:11:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7018982
            Orig. end                         :: 7031918
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001736.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082793
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12936
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="15"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12936
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12936
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7936](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7936)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    878..892
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            878..1639
                     /locus_tag="KFLA_RS32535"
                     /old_locus_tag="Kfla_6551"
     CDS             878..1639
                     /EC_number="3.5.2.9"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_function="GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002529034.1"
                     /locus_tag="KFLA_RS32535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6551"
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="WP_012924098.1"
                     /transl_table=11
                     /translation="MNTVDLNADLGEGYGSWAMGDDNALLDVVTSANVACGFHAGDPSI
                     MRAVCRRAADRDVAIGAHVGYADKPGFGRRFIDIEPAALRDEVLYQIAALDAFARVAGS
                     EVSYVKPHGALYNTIGHHEEQAAAVVAAVADYDRALPVLGLPGAVWLKLAEEAGLTVVH
                     EAFADRAYTPEGTLVSRRLPGAVLHDGREIAKRCVAMATGAPIKDVEGGELKLQPGSIC
                     VHGDTPGAVQIAQRVRKSLTDAGVELTPFAA"
     gene            1639..2268
                     /locus_tag="KFLA_RS32540"
                     /old_locus_tag="Kfla_6552"
     CDS             1639..2268
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385462.1"
                     /locus_tag="KFLA_RS32540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6552"
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="WP_012924099.1"
                     /transl_table=11
                     /translation="MRLLPCGSSALLVELADLDEVLGYYAALRAAPPAGVVDIVPAART
                     VMVAIDPAVTGLAALERSLRDTVAREDRRAGGDLVEIPVVYDGQDLADVAELLGCDVAE
                     VVRRHTSDEWTVAFCGFAPGFGYLTGQSEWNVPRRSSPRTKVPAGSVALAGEFSGVYPR
                     ESPGGWQLLGRTEVAVFDLDRDPAALLSPGRRVRFVDVRDTSRGAR"
     gene            2265..3152
                     /locus_tag="KFLA_RS32545"
                     /old_locus_tag="Kfla_6553"
     CDS             2265..3152
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011753588.1"
                     /locus_tag="KFLA_RS32545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6553"
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="WP_012924100.1"
                     /transl_table=11
                     /translation="MSGGFEVLETGPLTTVQDAGRLGQGALGIGRSGACDRTSYRLANR
                     LVGNAEDAAALEVTFGGLELVASSDLVYAVTGAPCAGIALNAPTVLRTGEVLRLGVPRT
                     GLRTYVAIRGGVNVAPVLGSRSTDLLSGLGPAPLSAGDVLAVGKECGPMPGVDLAPVAD
                     PPGGEVSVRVLPGPRRDWFTDADWDSLTGQSYTVSSNSNRIGVRLEGTPLERAREGELP
                     SEGMDLGALQIPPSGLPVLFLADHPVTGGYPVIGYVDGADLDLCAQLRPGQSLRFRSAQ
                     RTNPVGNGSVGSSR"
     misc_feature    2328..2330
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3104..4105)
                     /locus_tag="KFLA_RS32550"
                     /old_locus_tag="Kfla_6554"
     CDS             complement(3104..4105)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924101.1"
                     /locus_tag="KFLA_RS32550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6554"
                     /product="proline racemase family protein"
                     /protein_id="WP_012924101.1"
                     /transl_table=11
                     /translation="MRSVRTLSAIDSHTEGMPTRVITGGVGVIPGATMEERRQYFLADL
                     DDLRLFLMNEPRGHSAMSGAILQPPTRPDADWGVLYVEVSGCLPMCGHGTIGVATVLVE
                     SGMVPVSEPVTQVRLDTPAGLVVVDVAVRDGRAEHVTLRNVPAYSHALDATVEVKGLGT
                     VTYDLAYGGNFYAILPLEQLGIPFDRAEKDRILQAGLDIMDAINATDRPVHPVDPGIHS
                     CKHVQFTAPGQNGSHSRNAMAIHPGWFDRSPCGTGTCARMAQLHARGELGLGEDFVNES
                     FIGTSFTGRLLEETTVGDRPGVVPTVTGRAWITGMGNYLLDPTDPFPTGFVL"
     gene            complement(4102..5004)
                     /locus_tag="KFLA_RS32555"
                     /old_locus_tag="Kfla_6555"
     CDS             complement(4102..5004)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385459.1"
                     /locus_tag="KFLA_RS32555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6555"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_012924102.1"
                     /transl_table=11
                     /translation="MTEKLDGVIVATALPYAEDTAAPAGLRPDYDRYAEHCRWLIDNGC
                     RGVGPNGSLGEYSSLSDEERRRVARTAIEAVGDDGIVVVGVHGVGAHQARSWAEKAAED
                     GAHGVLCLPPTMYRANRSEVVHHFTEVAKAGLPVMAYNNPHDTKVDLTPGLLGELAQIE
                     NVVAVKEFTGDVRRILEIREQAPELTVVAGADDLTLEALLMGATGWFAGFPNVFPKESV
                     RLFDLALEGRLAEARALYEPLVAAFRWDSRVEFVQAIKWSMDYVGRYGGPCRPPRGPLV
                     PEHVAQLEQDMKRAVESLA"
     gene            complement(5001..6764)
                     /locus_tag="KFLA_RS32560"
                     /old_locus_tag="Kfla_6556"
     CDS             complement(5001..6764)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385458.1"
                     /locus_tag="KFLA_RS32560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6556"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_012924103.1"
                     /sec_met_domain="Fer2_4 (E-value: 3.9e-23, bitscore: 80.0,
                     seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.5e-21, bitscore:
                     74.8, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5.3e-06, bitscore:
                     25.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPFSRSAPGDPSEPRFGEPVEISVDGVPVAAVPGQTVAAALMAT
                     GRDSWRTTRGAERPRGVFCGIGACFDCLVVVNGTPDVRACQRTIQPGDAITTQAGAQLP
                     TRTGAAQPTQHSEALSFEVVVVGAGPAGLTAALAAAETGVSVGLVDAGRAVGGQFHRQL
                     PTEFAARRPERLQHGWARFVQLRDRVARHHRITQLAETSVWAIEEIEHGHRLWAQTGPA
                     DAGRRGVRAVDGRALVLAPGAYDRVLPFKGWDLPGVYSAGAAQALAKGQRIAVGQRVVL
                     AGTGPFLLPVAESLVGVGAEVAGMFEANSARTIARGWSSDPLVARGKIGEAAGYAGLLA
                     RHRIRPRTGWTVVAAHGDRRVEAVTVAKLDHDWRPIRGTEQQLEADAVCVGFGFTAQLE
                     LAVSTRCELTAGPDGGPAVRVDEHQQTSTPGVFAAGELTGIGGADLAAAEGRVAGAAAA
                     RFVTGSEAVLSQAHEEVAKGKRFAAALAAAHPVRPGWVEWSDDETLICRCEEVSRGELR
                     RAAADRELLPGRSLKLSSRVGLGMCQGRICSRNATCLTSPDQNAVVRNEFNRPIAVPVR
                     LKDLANPQEDQ"
     gene            complement(6761..7936)
                     /locus_tag="KFLA_RS32565"
                     /old_locus_tag="Kfla_6557"
     CDS             complement(6761..7936)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385457.1"
                     /locus_tag="KFLA_RS32565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6557"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_237706645.1"
                     /sec_met_domain="DAO (E-value: 2e-65, bitscore: 220.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDERSGRMPDVVVVGAGMIGAACAEALSAAGVDVLVLDRGTPAG
                     GTTAAGEGNVLVSDKEPGPELQLAIASRQEWPKVLARLPEQVADVEWEPKGGLVVATTD
                     PAPLEKFAAQQREAGVDAQLITPAEAFELEPLLTRAVTTAAYYPEDAQLQPVLATTALL
                     AAVRSRGGEVRSGVTAVSVRRAATGRVIGVETDAGLIDCVAVVNACGPWAGAFGAAVGG
                     PIEVLPRRGMILVTAPLPECVRHKVYDADYVGAVGSGDADLQTSTVVESTRSGTVLIGS
                     SRERIGFDDTVKVHVLRELARKAVGLFPFLADVAVIRTYGGFRPYAPDHLPVLGPDPRV
                     PGLWHATGHEGAGIGLAASTGRLVTELFIGVPPHVDPEPFRVDRPAVVGLP"
     gene            complement(7996..8598)
                     /locus_tag="KFLA_RS32570"
                     /old_locus_tag="Kfla_6558"
     CDS             complement(7996..8598)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385456.1"
                     /locus_tag="KFLA_RS32570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6558"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_012924105.1"
                     /transl_table=11
                     /translation="MLPAVGGQGAGRVLGVNLRARRDEQGISLSELARRSGIAKGTLSQ
                     LESGAGNPTIETVFSLSNALGVPVSALLSEPPASDLVLVRSADTDVLSGAAVDLRMLRR
                     LENPGSLFEIYDQRIRPGKVQHSTGHPGTEHHVVLTGRVRITARDRSQELGPGDYLAFR
                     ADAPHEYEALDGEVRSVLLLEYPPDTSPGVLETLHLD"
     misc_feature    8549..8562
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            complement(8612..9649)
                     /locus_tag="KFLA_RS32575"
                     /old_locus_tag="Kfla_6559"
     CDS             complement(8612..9649)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385455.1"
                     /locus_tag="KFLA_RS32575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6559"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_012924106.1"
                     /transl_table=11
                     /translation="MTKQQALVVGANGVIGSNLIAQLNGLPDWDVVGLSRRGGPGQLAV
                     DLLDIDDTRAKLAGLTDVTHVFYAAYQDRPTWAELVAPNLAMLVHVVEAVEPVARGLRH
                     VSLMQGYKVYGAHLGPFKTPAREDDPPHLPPEFNVDQQRFLEDRQQGKSWAWSALRPSV
                     VGGTALGNPMNLAVAIAGYASISKELGVPLRFPGKPGAYDALLELTDADLLAKATVWAA
                     TSPAAANQAFNITNGDLFRWNELWPRLAAWFGMDVAPPLQLSLQDVMADKEPVWKELQV
                     RHGLAGTPYAEVSSWGFADFVFGWDYDFFADGSKARRAGFHEYVETEQMFYRLFEDLRH
                     RRIIP"
     misc_feature    complement(9687..9705)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.23"
                     /tool="antismash"
     misc_feature    complement(9697..9709)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.58"
                     /tool="antismash"
     gene            9721..10623
                     /locus_tag="KFLA_RS32580"
                     /old_locus_tag="Kfla_6560"
     CDS             9721..10623
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385454.1"
                     /locus_tag="KFLA_RS32580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6560"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_012924107.1"
                     /transl_table=11
                     /translation="MATLRQLEYLVTVVDQGSFTRAAELLHVTQPALSHQIRALERSAG
                     GPLLERLPKNLRLTPTGRAMLPHARAALADAERARCAARQAAGLETGELQIATLYSVSL
                     GILPAALKAWRRQYADVGIRLFEHRHTDELAEAMTTGQADLAIGPSPAAWTGSTHRLGI
                     EEFVVVLASDDALASSDGEQAISLTELAERAWVHYTPGHGLADLLDQACAQAGFQPRIA
                     VRTEQTAAAPALAAAGLGPALVPANILPAGFDGLVLRPDPPICRTLTAYTRGTPDSLSA
                     AFIEVIQAAWPTIPGTKPG"
     gene            complement(10630..11085)
                     /locus_tag="KFLA_RS32585"
                     /old_locus_tag="Kfla_6561"
     CDS             complement(10630..11085)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012924108.1"
                     /locus_tag="KFLA_RS32585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6561"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_012924108.1"
                     /transl_table=11
                     /translation="MGLPDDAAEARAQGWRTLAALHARIEDELERALQKHYALSVSEYS
                     VLDVLARQDDYHLRMNQLSNAVVLSQSATTRLVNRLEDRKLLERYLCPTDRRGIYTEVT
                     KAGRDLLDEAQPTHDAVLTAALEAAAELPELAPLVKALAQLSLPAKV"
     misc_feature    11322..11337
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.63"
                     /tool="antismash"
     misc_feature    complement(11328..11341)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.91"
                     /tool="antismash"
     misc_feature    complement(11397..11412)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.23"
                     /tool="antismash"
     gene            11459..12259
                     /locus_tag="KFLA_RS32590"
                     /old_locus_tag="Kfla_6562"
     CDS             11459..12259
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020385445.1"
                     /locus_tag="KFLA_RS32590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6562"
                     /product="serine protease"
                     /protein_id="WP_012924109.1"
                     /transl_table=11
                     /translation="MTGKLTFARAALAAAVVALASTGAVGAAQAKPPAPPVTNIVGGSL
                     ASTAQAPWAIALNNSQSPSPSGQWCGATLVKANKIVTAAHCVTKARSTYTAIQGRDSLS
                     STTGRTSKIASIWKDPQYGRAPGHDVAVLTLATPFTGVPTLPLETSLAADAVGAQPTVY
                     GWGNTEGTGPADRFQKVLVPVLGDAYCGQVYANYDYVANGEICAGYKEGGKDSCQGDSG
                     GPLVLNGRLFGVVSWGIGCADAGNPGVYAEVATYAAALTAQINS"
ORIGIN
        1 cccgaagctc ggcggcgcgc tgtccgcact cgttgccatc ggcatcttca tctcgaagcg
       61 cgcggggctg gcgatggacc ggatcgtggt cgtgctcggc gcgctgatga tcgtgctgac
      121 cacctacatc gcgatcacct ccggcccgcc ggtcggccgc gcgctgaaga acgtcgtact
      181 gcccgagcag gtcgacttcc tggccatcac caccctgatc ggcggcacca tcggcggcta
      241 catcgtgtac gccggtgcgc accgcctgct ggactccggc atctcgggcc ccgagcacct
      301 ccgcgacatc acccgcggct cggtgaccgg catcctgatc accggcgtga tgcggatcgt
      361 gctgttcctg gcgatcctcg gcgtggtggc cggcggcgcg aagctcgacc cggccagccc
      421 ggccgcttcg gcgttccagc aggccgccgg tgaggtgggc ctgcgggtct tcggcatcgt
      481 gctgtgggcc gccgcgatca ccagtgtgat cggcgcgtcg tacacgacgg tctcgttcat
      541 cacctcgcgg acgaggacca gcgagcggct gcggaccgcg ctggtggtcg gcttcatcgc
      601 cgtcaccacc atcatctacc tgtcggtcgg taccgcaccg accacgctgc tggtgttcgc
      661 cggcgcgttc aacggcttgc tgctgccggt cgggatcggt gtgctgctct gggtggcctg
      721 gcggcgcaag gacctgctga acgggtaccg gtacccggcc tggctgctcg gcatcggtgg
      781 cgcggcctgg ctgctcacca tctacctggc ggtgcgctcg gtgcgtcccg tcatcgacct
      841 gttcaactga tccagccgga cgcctgaagg aggacccatg aacaccgtcg atctgaacgc
      901 cgatctcggc gagggctacg gcagctgggc gatgggcgac gacaacgccc tgctcgacgt
      961 cgtcaccagc gcgaacgtcg cctgcggctt ccacgccggc gatccctcca tcatgcgggc
     1021 ggtctgccgg cgggccgccg atcgcgacgt ggcgatcggc gcgcacgtcg ggtacgccga
     1081 caagcccggc ttcggccgcc ggttcatcga catcgagccg gccgcactgc gcgacgaggt
     1141 gctgtaccag atcgccgccc tggacgcctt cgcccgggtt gccgggtcgg aggtcagcta
     1201 tgtcaagccg cacggcgcgc tctacaacac gatcgggcac cacgaggagc aggccgcggc
     1261 cgtggtcgcg gccgtcgccg actacgaccg cgcgctgccg gtgctcggtc tgcccggcgc
     1321 ggtctggctg aagctggccg aggaggccgg tctgaccgtc gtgcacgagg cgttcgccga
     1381 ccgggcctac acgcccgaag gcacgctggt gtctcgccgg ctgcccggtg cggtgctgca
     1441 cgacggccgc gagattgcca agcggtgcgt ggcgatggcc accggcgcgc cgatcaagga
     1501 cgtcgagggc ggcgagctga agctgcagcc cggttcgatc tgcgtgcacg gggacacccc
     1561 gggcgcggtt cagatcgcgc agcgggtccg caagagcctc accgacgccg gggtcgaact
     1621 gaccccgttc gccgcctgat gcgcctgctt ccctgcggca gttccgcgct gctggtggag
     1681 ctcgcggacc tcgacgaggt gctcgggtac tacgcggcgc tgcgggccgc gccgccggcc
     1741 ggtgtcgtgg acatcgtgcc ggcggcccgg accgtgatgg tggcgatcga cccggccgtc
     1801 accggcctgg ccgcgctcga gcggtccttg cgcgacacgg tggcgcgcga ggaccgccgg
     1861 gccggcggcg acctggtcga gatcccggtc gtgtacgacg gacaggatct ggccgacgtc
     1921 gccgagctgc tcggctgcga cgtggccgag gtggtccggc ggcacacgtc cgacgagtgg
     1981 acggtcgcct tctgcgggtt cgctccgggc ttcggctacc tgaccggcca gtcggagtgg
     2041 aacgtgccgc ggcggtcgtc gccgcggacg aaggtgccgg ccggttcggt cgcgctggcc
     2101 ggtgagttca gcggggtcta cccgcgcgag tcgcccggcg gctggcagct gctcggccgg
     2161 acggaggtcg ccgtcttcga cctcgaccgc gatccggcgg cgctgctgag ccctggtcga
     2221 cgggtgcgct tcgtcgacgt tcgggacacg tcgcggggag cccggtgagc gggggcttcg
     2281 aggttctgga gaccggtccg ctgacgaccg tgcaggacgc cgggcggtta ggtcagggcg
     2341 cgctcggcat cggccggtcc ggcgcctgcg accgtacgtc gtaccggctg gcgaaccggc
     2401 tggtcggcaa cgccgaggac gcggcggcgc tggaggtgac cttcggcggg ctcgagctgg
     2461 tcgcgtcgtc cgacctggtc tacgcggtga ccggtgcgcc gtgcgccggc atcgccctga
     2521 acgcgccgac ggtgctgcgc acgggcgagg tgctacggct cggcgtgccc cggaccgggc
     2581 tgcgcacgta cgtcgcgatt cgcggcggcg tgaacgtcgc gccggtgctc ggctcccggt
     2641 cgaccgatct gctgtccggc ctgggcccgg ctccgttgtc ggccggagat gtgcttgctg
     2701 tcggcaagga gtgtggcccg atgccggggg tcgacctggc tccggtcgcg gatccgccgg
     2761 ggggtgaggt gtccgtgcgc gtgctgcccg gtccgcgccg cgactggttc accgacgccg
     2821 actgggactc gttgaccggc cagtcctaca ccgtcagcag caacagcaac cggatcggcg
     2881 tacgcctgga aggcaccccg ctggaacgcg cccgcgaagg cgagctgccc agcgagggca
     2941 tggacctggg cgccctgcag atcccaccct ccggtctgcc cgtgctcttc ctcgccgacc
     3001 accccgtcac cggcggctat cccgtcatcg gctacgtgga cggcgccgat ctggacctct
     3061 gcgcccaact ccgccccggc cagtccctgc gcttccgcag tgctcagagg acgaatccgg
     3121 tggggaacgg gtcggtcgga tccagcaggt agttgcccat gccggtgatc cacgcgcggc
     3181 cggtcaccgt cggcaccacc cccggccggt cgccgaccgt cgtctcttcc agcagccgcc
     3241 cggtgaagct cgtgccgatg aacgactcgt tgacgaagtc ctcccccagc cccagctcac
     3301 cgcgcgcgtg cagctgcgcc atccgtgcac acgtcccggt cccgcacggc gaccggtcga
     3361 accaccccgg gtgaatcgcc atcgcgttgc gcgagtggct cccgttctgc ccaggtgcgg
     3421 tgaactgcac gtgcttgcag ctgtggatgc ccggatccac cgggtgcacc ggccggtcgg
     3481 tcgcgttgat cgcgtccatg atgtccagcc cggcctgcag gatgcggtcc ttctcggccc
     3541 ggtcgaacgg aattcccagc tgctccagcg gcaggatcgc gtagaagttg ccgccgtagg
     3601 ccaggtcgta ggtgaccgtg cccagcccct tcacctcgac cgtcgcgtcc agcgcgtgcg
     3661 agtacgccgg gacgttgcgc agcgtcacgt gctcggcccg cccgtcgcgt accgcgacgt
     3721 cgaccacgac cagcccggcc ggcgtgtcca gccgcacctg cgtgaccggt tcgctgaccg
     3781 gcaccatgcc ggactcgacc agcacggtgg cgaccccgat cgtgccgtgc ccgcacatcg
     3841 gcagacagcc ggacacctcg acgtagagca caccccagtc cgcgtcgggc cgggtcggcg
     3901 gctgcaggat cgcgccgctc atcgccgagt ggccgcgcgg ctcgttcatc aggaacagcc
     3961 gcaggtcgtc gaggtcggcc aggaagtact gccgccgctc ctccatggtc gcgcccggga
     4021 tcaccccgac gccgccggtg atcacccggg tcggcatgcc ctcggtgtgc gagtcgatcg
     4081 cgctcagcgt gcggacggat ctcatgccaa cgactctacg gcgcgcttca tgtcctgctc
     4141 gagctgtgcg acgtgctcgg gcaccagcgg tccgcgcggc ggccggcagg gaccgccgta
     4201 ccggccgacg tagtccatcg accacttgat cgcctgcacg aactcgaccc gcgagtccca
     4261 gcggaaggcg gcgaccagcg gctcgtacag cgcccgggcc tcggccagcc ggccttccag
     4321 cgcgaggtcg aacagccgga ccgactcctt cgggaagacg ttcgggaagc cggcgaacca
     4381 gccggtggcg cccatcagca gcgcttccag ggtcaggtcg tcggcgcccg cgaccacggt
     4441 cagctccggc gcctgctcgc ggatctccag gatccgccgc acgtcaccgg tgaactcctt
     4501 caccgcgacc acgttctcga tctgcgcgag ctcgcccagc aggccgggcg tcaggtcgac
     4561 cttggtgtcg tgcgggttgt tgtaggccat caccggcagc ccggccttcg cgacctcggt
     4621 gaagtggtgc accacctcgg accggttcgc ccggtacatc gtcggcggca ggcacaggac
     4681 gccgtgcgcg ccgtcctcgg ccgccttctc cgcccagctg cgcgcctggt gcgccccgac
     4741 cccgtgcacg ccgaccacca cgatcccgtc gtcgccgacc gcctcgatcg cggtccgcgc
     4801 gacccggcgc cgctcctcgt cgctgagcga ggagtactcc ccgagcgacc cgttggggcc
     4861 gacaccgcgg cagccgttgt cgatcaacca ccggcagtgc tcggcgtacc ggtcgtagtc
     4921 gggccgcaac ccggccggcg cggccgtgtc ctcggcgtac ggcagcgcgg tggcgacgat
     4981 cacgccgtcg agcttctcgg tcactggtcc tcctgggggt tggctaggtc cttcaggcgt
     5041 acggggacgg cgatcgggcg gttgaactcg ttccgtacga cggcgttctg gtcgggtgag
     5101 gtgaggcagg tcgcgttccg ggagcagatc cgcccctggc acatgcccag gcccacccgg
     5161 ctcgacaact tgaggctgcg ccccgggagc agctcccgat cggccgccgc ccgccgcaac
     5221 tcaccgcggg agacctcctc acaccggcag atcagcgtct cgtcgtcgct ccactccacc
     5281 caccccggcc ggaccggatg agcagccgcc agggccgcgg caaatcgctt gcccttagca
     5341 acctcttcgt gggcctggga cagcacggct tccgagccgg tgacgaagcg ggctgccgcc
     5401 gcaccggcga cccgtccctc ggcggcggcc aggtcggcgc cgccgatgcc ggtgagttcg
     5461 ccggcggcga agactccggg cgtactggtc tgctggtgct cgtcgacccg gacggcggga
     5521 ccgccgtcgg gcccggcggt gagttcgcag cgggtggaga cggccagttc cagctgtgcg
     5581 gtgaagccga agcccacgca gaccgcgtcg gcttcgagct gctgctcggt cccgcggatc
     5641 gggcgccagt cgtggtccag cttcgccacc gtgacggcct cgacccgtcg gtcaccgtgc
     5701 gcggcgacga ccgtccatcc cgtccgaggg cggatccggt gccgcgccag cagtccggcg
     5761 tacccggctg cttcgccgat cttgccccgg gcaaccaggg ggtcgctcga ccagccgcgc
     5821 gcgatcgtcc gggccgagtt ggcctcgaac atgccggcca cctcggcccc gacgccgacc
     5881 agcgactccg ccaccggtag caggaacggc cctgtgcccg ccaagaccac ccgctgcccg
     5941 accgcgatcc gctgcccctt cgccagcgct tgcgcggccc ccgcgctgta gaccccgggc
     6001 aggtcccacc ccttgaacgg cagcacccgg tcgtacgcac ccggcgccag caccagagcc
     6061 cgcccgtcca cagcccgtac gccgcgccgc cccgcgtcgg ccggtccggt ctgtgcccac
     6121 agtcgatgtc cgtgctcgat ctcctcgatc gcccacaccg acgtctccgc caactgggtg
     6181 atccggtggt gccgagccac ccggtcccgc aactgcacga accgggccca tccgtgctgc
     6241 aaccgctccg gccgccgcgc cgcgaactcg gtcggcaact gccggtggaa ctgtccgccc
     6301 acggcccgtc ccgcgtccac cagcccaacc gagactcccg tctccgcagc tgccagtgcc
     6361 gcggtcaaac cagcaggccc cgcgcccacg accaccacct cgaacgacag tgcctccgag
     6421 tgctgcgtgg gctgcgcagc gccggtccgg gtcggcagct gcgcgccggc ctgcgtcgtg
     6481 atggcgtcgc ccggctggat cgttcgttgg caggcgcgga cgtcgggggt tccgttgacg
     6541 accaccaggc agtcgaagca ggcgccgatg ccgcagaaca ctccgcgcgg acgctcggcc
     6601 ccgcgggtgg ttcgccacga gtcccgcccg gtggccatca gcgcggcggc caccgtctgc
     6661 ccgggaaccg cggcgaccgg gaccccgtcc accgagatct cgaccggctc tccgaagcgc
     6721 ggctcggacg gatcgcccgg tgcggaccgc gaaaaggggc tcatggcaac cccactacgg
     6781 ccggtcggtc gacccggaag ggctccgggt cgacgtgcgg cggcacaccg atgaagagct
     6841 ccgtcaccag gcggccggtc gacgccgcga ggccgatgcc ggcaccttcg tggccggtcg
     6901 cgtgccaaag gcccggcacc cgcggatccg gcccgaggac cgggaggtgg tccggggcgt
     6961 agggccggaa accgccgtac gtccgtatca ccgcgacgtc ggcgagaaac gggaacaggc
     7021 cgaccgcctt gcgcgccagt tcccgcagga cgtgcacctt gaccgtgtcg tcgaagccga
     7081 tccgctcccg gctggaaccg atcaggaccg tgccactccg ggtcgactcg accaccgtcg
     7141 aggtctgcag gtccgcgtcg ccgctgccga ccgcgccgac gtagtccgcg tcgtacacct
     7201 tgtgccgtac gcactccggc agcggcgcgg tgaccaggat catgccgcgg cgtggcagca
     7261 cctcgatcgg tccgccgacc gccgcgccga aggctcccgc ccaggggccg caggcgttga
     7321 cgacggccac gcagtcgatc aggcccgcgt ccgtctccac accgatcacc cggccggtgg
     7381 ctgcgcgtcg tacggacaca gcggtgacgc cggaccggac ctcgccgcct cgggagcgaa
     7441 cggcggccag cagggccgtg gtggcgagga ccggctgcag ctgcgcgtcc tcggggtagt
     7501 aggcggccgt cgtcaccgcg cgggtcaaca gcggctcgag ctcgaacgcc tcggccggcg
     7561 tgatcagctg cgcgtcgacg cccgcctcgc gctgctgggc cgcgaacttc tccagcggtg
     7621 cgggatccgt ggtcgcgacc accaggccgc ccttcggctc ccactcgacg tcggcgacct
     7681 gctccggcag ccgggcgagc accttcggcc actcctggcg cgacgcgatc gccaactgca
     7741 gctcgggccc gggctccttg tcggagacca gcacgttgcc ttcgccggcc gccgtcgtac
     7801 caccggccgg ggtgccacgg tcgagcacga gcacgtcgac gccggccgcc gagagggctt
     7861 cggcgcaggc ggcaccgatc attcccgccc cgaccaccac cacgtccggc atccgcccac
     7921 tccgctcatc gttcacttta atgaacgctg cgagcgtacg gcgcgcgccc gggtcaggtc
     7981 aacggccgag cggcctcagt ccaggtgcag ggtttccagc acacccgggc tggtgtccgg
     8041 cgggtactcc aggagcagga ccgagcgcac ttcgccgtcc agcgcctcgt actcgtgcgg
     8101 cgcatcggcc cggaaggcca ggtagtcgcc gggtcccagc tcctggctgc ggtcccgtgc
     8161 ggtgatgcga acccgtcccg tgagaacgac gtggtgctcg gtgccgggat ggccggtcga
     8221 gtgctgcacc ttgccggggc ggatgcgctg gtcgtagatc tcgaacaggc tgccgggatt
     8281 ctcgagccgc cgcagcatcc gcaggtcgac cgccgcgccg ctgagcacgt cggtgtcggc
     8341 ggagcggacc aggaccaggt cggacgccgg cggctcgctc agcagggccg acaccgggac
     8401 gccgagagcg ttcgacagac tgaacaccgt ttcgatggtg ggattgcccg cgccggactc
     8461 cagctgcgac agcgtgccct tcgcgatgcc ggaccggcgg gcgagctcgg acagggagat
     8521 gccctgctcg tcccggcgcg cccgcaggtt gaccccgagc acgcgccccg ctccctgacc
     8581 gcccacagcc gggagcatgc cacaccctgg ctcaggggat gatccggcgg tgccgcaggt
     8641 cctcgaacag gcggtagaac atctgctcgg tctccacgta ctcgtggaaa ccggcccggc
     8701 gggccttcga cccgtcggcg aagaagtcgt agtcccagcc gaagacgaag tcggcgaacc
     8761 cccacgacga cacctcggcg tacggcgtac cggcgaggcc gtgacggacc tgcagctcct
     8821 tccagaccgg ctccttgtcg gccatcacgt cctgcagcga cagctgcagc ggcggcgcca
     8881 cgtccatccc gaaccacgcg gccagcctcg gccacagctc gttccagcgg aacaggtcgc
     8941 cgttcgtgat gttgaacgcc tggttcgccg cggccgggct ggttgccgcc cagacggttg
     9001 ctttggccaa caagtcggcg tcggtcagct ccagcagcgc gtcgtacgcg ccgggcttgc
     9061 cggggaaccg cagcggaacg cccagctcct tcgagatcga cgcgtagccg gcgatcgcga
     9121 cggccaggtt catcgggttg ccgagcgcgg tgccgccgac cacggagggc cgcagcgccg
     9181 accaggccca gctcttgccc tgctgccggt cctccaggaa ccgctgctgg tcgacgttga
     9241 actccggcgg caggtgcggc ggatcgtcct cccgcgccgg cgtcttgaac gggccgagat
     9301 gtgcgccgta caccttgtag ccctgcatca ggctgacgtg ccgcagcccg cgcgcgaccg
     9361 gctcgacggc ttcgaccacg tgcaccagca tcgcgaggtt cggcgcgacc agctcggccc
     9421 aggtcggccg gtcctggtac gccgcgtaga acacgtgggt cacgtcggtc agcccggcca
     9481 gcttcgctcg ggtgtcgtcg atgtccagca ggtcgacggc gagctgcccc ggcccaccgc
     9541 gccgggagag tccgaccacg tcccagtcgg gtaggccgtt cagctgcgcg atcaggttgc
     9601 tgccgatcac gccgttcgct ccgaccacca gggcctgctg tttcgtcatg tccccagcct
     9661 gtgggagaac ctgtggataa gtccaaggca tcctttttac aatgtgcata aactcagctc
     9721 atggctacgc tgcgtcagct ggagtacctg gtgaccgtgg tcgaccaggg ctccttcact
     9781 cgcgccgccg agttgctgca cgtcacccag cccgcgctgt cccaccagat ccgggcgctc
     9841 gaacgctccg cgggcggacc gctgctggag cgcctgccga agaacctgcg cctcaccccg
     9901 accggccgcg cgatgctgcc ccacgcccgg gccgcgctgg ccgatgccga acgcgcccgg
     9961 tgcgccgccc ggcaggcggc cggcctggag accggtgagc tgcagatcgc gacgctctac
    10021 tcggtcagcc tcggcatcct tccggccgcg ttgaaggcct ggcggcgcca gtacgcggac
    10081 gtaggcatcc gcctcttcga gcaccggcac accgacgagc tcgccgaggc gatgaccacc
    10141 ggccaggccg acctggccat cggcccgtca ccggccgcgt ggaccggctc cacccaccgc
    10201 ctgggcatcg aggagttcgt cgtcgtcctg gcctcggacg acgcgctcgc gtcctcggac
    10261 ggggagcagg ccatctcgct gaccgagttg gccgagcgcg catgggttca ctacaccccc
    10321 ggccacggcc tggccgatct gctcgaccag gcttgcgcgc aggcgggatt ccagccccgg
    10381 atcgcggtcc gtaccgaaca gaccgccgct gctccagccc tcgccgcggc agggctcggc
    10441 cccgccctgg tcccggccaa catcctgccg gccggcttcg acgggctggt cctgcgcccc
    10501 gatccgccga tctgccgcac cctcacggcg tacacgcgcg gcacgccgga ctcgctctcc
    10561 gccgccttca tcgaggtgat ccaggcggcc tggccgacca ttcccggtac caagccgggg
    10621 tgaccggctt cagaccttgg cgggcaggga gagctgagcc agcgccttca ccaggggcgc
    10681 cagctcgggg agttcggcgg cggcctcgag cgcggccgtc aggactgcgt cgtgcgtggg
    10741 ctgggcctcg tcgagcaggt cacggccggc cttggtgacc tccgtgtaga tgccgcgacg
    10801 gtcggtcggg cacaggtagc gctcgagcag cttgcgatcc tccagccggt tcaccaggcg
    10861 ggtggtcgcc gactggctga gcaccacggc gttcgacagc tggttcatcc gcaggtggta
    10921 gtcgtcctgc cgcgccagca cgtcgagcac gctgtactcg ctgaccgaca gcgcgtagtg
    10981 cttctgcaaa gcgcgctcga gctcgtcctc gatccgcgcg tgcaaggccg cgagggtgcg
    11041 ccacccctgg gcccgcgcct ccgcggcgtc gtccggtagt cccacagctc ctcctcacac
    11101 cccgcgtcca cagccggccc agcactgcgg ttacctgtgc aataaccggc gcgtgcaact
    11161 atcgcgcacg ctggtattac tcacagatta ccgtccgaag caatagtccc cacgatcaag
    11221 cggttcgacc gagcgcccac agcagccccg ccgcgcccgc tgggagaact tgtggttgcg
    11281 acctccccga ccgcgccggt cggaggtttt cccttgccct gcgcaccttt ttgtgacaca
    11341 gcgctgaccc gacaccgatg tgcccggtga atcgcttgct tcacggacgg tgaagcgatg
    11401 actcttctca gtcagaggcc gcaccgccca cgcggccgat gacacctgga gtgtggacat
    11461 gaccggaaag ctcaccttcg cccgtgcggc cctggccgcc gctgtggtcg ctctcgcttc
    11521 gaccggagcg gtcggtgcgg cgcaggccaa gccgccggcc ccgccggtga ccaacatcgt
    11581 cggcggctcc ctggcgagca ccgcgcaggc gccctgggcg atcgcgctga acaacagcca
    11641 gtccccgtcc ccgagcggcc agtggtgcgg tgccaccctg gtgaaggcga acaagatcgt
    11701 gaccgccgcg cactgcgtga ccaaggcgcg cagcacctac accgcgatcc agggccgcga
    11761 cagcctgagc agcacgaccg gccggacctc gaagatcgcg tcgatctgga aggacccgca
    11821 gtacggccgg gcgccgggcc acgacgtcgc cgtcctgacc ctggccacgc cgttcaccgg
    11881 cgtaccgacg ctgccgctgg agaccagcct cgcggcggac gccgtcggtg cgcagccgac
    11941 ggtgtacggc tggggcaaca ccgagggcac cggtccggca gaccgcttcc agaaggtgct
    12001 cgtgccggtc ctgggtgacg cgtactgcgg tcaggtctac gcgaactacg actacgtcgc
    12061 caacggtgag atctgcgccg gctacaagga aggcggcaag gattcctgcc agggcgactc
    12121 cggcggcccg ctcgtgctca acggccggct cttcggcgtc gtctcctggg gcatcggctg
    12181 cgccgatgcc ggcaacccgg gcgtgtacgc cgaggtcgcg acgtacgccg cggcgctgac
    12241 cgcccagatc aacagctgat cgccctgctc gcaggctgac cgactactca gccggcaggc
    12301 tgcaccgacg gccgttccct ttcccgggag cggccgtcgt cgggtcagcc gatcggccgg
    12361 gcgatgacga cggcattgct ctcgtagtcc gtgccgttcc agtcctcgca ggtgacaagc
    12421 accagccggc cgggcacggt ctggtcgaag agccggccgg cctgcttggc cagggcccgt
    12481 ttgcggtagg tggtgaccga gacgacggag taccgcagcg ttcgccggcc ggtggcgacg
    12541 ctgaccgcgt cccccggtcg caacgtgccg aggtcgtcga acgcgccgcc gccggtgtgc
    12601 acggtgtgcc cggtgatgat ggccgatccc cgggcggctc ccggccgcgc cccgtcggac
    12661 caccagccga ccagccgggg attcgccggc gggatcaacg tgctgccgtt ggcccggatc
    12721 ccgagaaccc gcgccgagac cttgagtcgc ggtacgacga tccgctgcgg accgcccgct
    12781 gccggccggt gcgtgccggt ggcctcgggc agggccgtgg acggcgtgct cggctggttc
    12841 gccggtttgc ccggcgtcgt cggccggccc ggggctggag tcgagggttt ggccggtgac
    12901 ttggccgggg acgacggggc ggcagacggc acaagg
//
