LOCUS       NC_013729              22892 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Kribbella flavida DSM 17836, complete sequence.
ACCESSION   NC_013729
VERSION     NC_013729.1
KEYWORDS    RefSeq.
SOURCE      Kribbella flavida DSM 17836
  ORGANISM  Kribbella flavida DSM 17836
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 7579488)
  AUTHORS   Pukall,R., Lapidus,A., Glavina Del Rio,T., Copeland,A., Tice,H.,
            Cheng,J.F., Lucas,S., Chen,F., Nolan,M., Labutti,K., Pati,A.,
            Ivanova,N., Mavromatis,K., Mikhailova,N., Pitluck,S., Bruce,D.,
            Goodwin,L., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D., Chen,A.,
            Palaniappan,K., Chain,P., Rohde,M., Goker,M., Bristow,J.,
            Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C., Klenk,H.P.
            and Brettin,T.
  TITLE     Complete genome sequence of Kribbella flavida type strain (IFO
            14399)
  JOURNAL   Stand Genomic Sci 2 (2), 186-193 (2010)
   PUBMED   21304701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Kribbella flavida DSM 17836
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024345.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,131
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 7,033
            CDSs (with protein)               :: 7,033
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 8 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 4 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name             :: Kribbella flavida DSM 17836
            Culture Collection ID :: DSM 17836, JCM 10339, KCTC 9580, NBRC 14399
            GOLD Stamp ID                     :: Gi02235
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: GeneMark
            Isolation Site                    :: Soil from China
            Isolation Country                 :: China
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:11:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6982598
            Orig. end                         :: 7005490
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001736.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082793
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22892
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="14"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22892
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22892
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12892](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12892
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    50..68
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.35"
                     /tool="antismash"
     gene            complement(339..1172)
                     /locus_tag="KFLA_RS32370"
                     /old_locus_tag="Kfla_6517"
     CDS             complement(339..1172)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021214.4"
                     /locus_tag="KFLA_RS32370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6517"
                     /product="cytochrome c oxidase assembly protein"
                     /protein_id="WP_012924066.1"
                     /transl_table=11
                     /translation="MTHSHDHQATGLATFAALLTALVLVIVYAWAVQRLQRRGDTWSVG
                     RFLCFAGGVLGLTAAFALPLPGRAFTAHMTQHLLIGMLAPLLIVLARPLTLALRVLRPG
                     RARQSLLALAHSRWSSFVQLLPVVAVLEVGGLWALYRTPLFAASQERPWLHAVVHGHVI
                     VSGLLFAFVICQLDPVRRRYGLVPRAATVVLAGAAHAVLAKSLYASPPPGTTFAAADLA
                     VGAKVMYYGGDVVEILLAVVLALQWYSAEGRRFTRGLRPGTSSGRALGRLGRASR"
     gene            complement(1169..1627)
                     /locus_tag="KFLA_RS32375"
                     /old_locus_tag="Kfla_6518"
     CDS             complement(1169..1627)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021516.4"
                     /locus_tag="KFLA_RS32375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6518"
                     /product="DUF2243 domain-containing protein"
                     /protein_id="WP_041289582.1"
                     /transl_table=11
                     /translation="MQPPPEYGVLLPTRSVWAGVLIGIGIAAFVDETVFHQLLHWHHFY
                     DRSTPAAGLVSDGLFHAFGWFAVVIGLVMVADLRRRAGLVGRSLAGGILLGAGAFQLYD
                     GTVQHKLLDLHQIRYQVDLTLYDWTWNVLAVLMVVAGVLLIRAGRTRP"
     CDS             1637..1747
                     /gene="allorf_6984235_6984345"
                     /locus_tag="allorf_6984235_6984345"
                     /protein_id="allorf_6984235_6984345"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGRWAGGGHRNTLHAGTVDRRYPDPRALSEPAACRR"
     CDS_motif       1637..1684
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGRWAGGGHRNTLHAG"
                     /locus_tag="allorf_6984235_6984345_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1685..1747
                     /prepeptide="core"
                     /locus_tag="allorf_6984235_6984345_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="2293.6"
                     /monoisotopic_mass="2292.2"
                     /core_sequence="TVDRRYPDPRALSEPAACRR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGRWAGGGHRNTLHAG"
                     /leader_location="[1636:1684](+)"
                     /alternative_weights="2311.6"
     gene            complement(1761..2333)
                     /locus_tag="KFLA_RS32380"
                     /old_locus_tag="Kfla_6519"
     CDS             complement(1761..2333)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391559.1"
                     /locus_tag="KFLA_RS32380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6519"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_012924068.1"
                     /transl_table=11
                     /translation="MPAKTDHDARRRDVSAAVWKVVAADGFGGLTLRAVAAAMGGSTGL
                     VTHYFPSKQALVLHALEVAEQRTQALVPDTTDLRTALIAVLPLTAETTELNRVWVSSWD
                     VALADPQLAALEQARYRRWRTRLKPLVIQAQNDGDLITGDAMDLAAGLAAFTHGLVVQA
                     LVDPRTFGRKRLELLLDAHLTALRPRR"
     gene            2409..2963
                     /locus_tag="KFLA_RS32385"
                     /old_locus_tag="Kfla_6520"
     CDS             2409..2963
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391558.1"
                     /locus_tag="KFLA_RS32385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6520"
                     /product="GNAT family protein"
                     /protein_id="WP_012924069.1"
                     /transl_table=11
                     /translation="MFAATIADNAELRPLEPWQAAEFQAHVDKARTNLSPYLPWAVTVV
                     DDRTAREFLQRYAERQAADEGRIYGIWLADELVGGLLFRTFDTDDGSCEIGVWLAGHAE
                     GRGLVTRSAQLLIDWALGVRGLSRVEWRCVPSNTRSIAVARRLGMTHEGTLRQAFPYRG
                     EAHDVQTWSLLRTEWEDRSRE"
     gene            2991..3863
                     /locus_tag="KFLA_RS32390"
                     /old_locus_tag="Kfla_6521"
     CDS             2991..3863
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013672.4"
                     /locus_tag="KFLA_RS32390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6521"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_012924070.1"
                     /transl_table=11
                     /translation="MTGARGWTLAAFCAVVAVLLGSCGGSSAPPSVQDSPTPTVSASTP
                     AQPSSKPSTTPVRRPGESRARTLMPIVQHGPRDKPRIALTFDADLTTAMRRRLHSGQVK
                     SYYNEALIQHLRDLRVPATLFLTGLWMEQYPDRTRELAADPLFELATHSYDHRAFTKRC
                     YTLGTVPRAGMLTDVRRAVTILDELDPQATRWFRFPGGCYDGTALHELAPAAVTAVGLD
                     VPGADGFAKSSESIVGQVLQNARNGSIVVLHMHGGDNAPLTDEAIPSIVKSLRLRGYEL
                     VTVTELMAG"
     gene            3979..5337
                     /locus_tag="KFLA_RS32395"
                     /old_locus_tag="Kfla_6522"
     CDS             3979..5337
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391555.1"
                     /locus_tag="KFLA_RS32395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6522"
                     /product="APC family permease"
                     /protein_id="WP_012924071.1"
                     /transl_table=11
                     /translation="MTTTESRSRGRSLRGNALGVGAGTAIGVASTAPAYSLAVSVGLLA
                     VYTGAAAPLVLAVSAIPVVLVALCFRELNRAEPDCGTTFPWTEKAFGLSVGRMVGWTTV
                     MACVLVMSNLAQVAAVYTYALLGLETAEESRLAQAGLGTVFILGMALLAYRGIRVAAGT
                     QLLLLSVELVALIWFVVGAFREAGTVSIPAFSDTGDGAWAAGVLVAVFLYWGWDSSFSV
                     NEESRNPRSTPAIAALVANGILVVLYVVVAWAAVAYAGTGQLAEIADDDFLAVLGADLL
                     GTAGGKLLIAAVLVSALASTQTTILPTARTMLSMARRDAFPGQFARISARYQTPSVSTW
                     TFATASVLVYVVLVLTSDAVLADSVAAVSILVSLYYLATALAVPVYFSGELRGRMVQRL
                     VVPVLATVSFATVLVLAVADVGTGPLVVVGVTMVVGAAVMFSMKPPAEGEGRR"
     gene            5334..5750
                     /locus_tag="KFLA_RS32400"
                     /old_locus_tag="Kfla_6523"
     CDS             5334..5750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391554.1"
                     /locus_tag="KFLA_RS32400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6523"
                     /product="lipoprotein"
                     /protein_id="WP_012924072.1"
                     /transl_table=11
                     /translation="MSDRRMRSVGITLGLTALVAASLTGCSSDDEDQPDYAAICVDPET
                     EQRTSDENCKDEREYNGSGAGFFWFYMATRSGVLVPPIGGRYPAGSGTYTVPRTGTGGA
                     APSVRRGGLNPGGGDIGTITRGGFGKSGKGSSGG"
     gene            5750..6973
                     /locus_tag="KFLA_RS32405"
                     /old_locus_tag="Kfla_6524"
     CDS             5750..6973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391553.1"
                     /locus_tag="KFLA_RS32405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6524"
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="WP_012924073.1"
                     /transl_table=11
                     /translation="MWRHAIKPRPDWRDKVVEQGLVYPMTELPDGTERPYWNESAWYEV
                     TMEEVLHLERVTEELYEMCKHAASVMAAGDRFSDAQLGLAPGTLPLVQQSLKRDDLSVY
                     ARFDLVWNGVEPKMLEINGDTPTGLLESAVIQWNWLEDVFPDADQWNSVHDRLVKWWSE
                     QLAAGRLPGNEAHFFNSGAETTGEEAMTVAYLRDTAAMAGLATYGHEIEDLGWESAQRA
                     FVDWGGRKIRTAFKLYPWEDMLDDEFGRYLLAGVEREPVQWIEPIWKTMLSTKAILPVL
                     WELYPDHPNLLPAYFDHPGDLLEWVAKPLHGREGGNIRIHTIGGDDHVHDGPYDTGTMV
                     YQEWSPLPSYEGNRAVIGSWIVDGAAAGMMVRESDGPITDYYARFVPHAIGTAPRPDEE
                     TIKQWLTE"
     gene            complement(6974..8434)
                     /locus_tag="KFLA_RS32410"
                     /old_locus_tag="Kfla_6525"
     CDS             complement(6974..8434)
                     /EC_number="1.2.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391551.1"
                     /locus_tag="KFLA_RS32410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6525"
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_012924074.1"
                     /sec_met_domain="Aldedh (E-value: 2.7e-168, bitscore:
                     559.0, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSREQEVVQECPTELFVGGKWRAAESGRTLAVEDPATGTTLCEVA
                     DAGPADGVAALDAAVAAQADWAATAPRERGEILRRTYELMTERADELALLMTLEMGKPV
                     AESKGEIAYAAEFFRWFAEEAVRIDGGYQVAPNGKGRFLVTRQPVGPCLLITPWNFPAA
                     MGARKIGPAVAAGCTMVIKPAAQTPLSMLKLAELMTEAGLPAGVLNVVTTSDSGGVMEP
                     LIRDPRARKLSFTGSTQVGRKLIEQSAEQVLRTSMELGGNAPFLVFPDADLDKAVEGAL
                     QAKMRNGGEACTAANRIYVHSSVLDDFATRLTERMSALRVGRGTEDGVEVGPLIDAEQR
                     DKVKELVDDAVQQGARVLTGAEVAEGKGYFYPPTVLTDVPRSARLQKEEIFGPVAPLTA
                     FDTEDEAVAMANDTEFGLVSYLFTNDLSRALRVCEKLETGMIGLNQGIVSNPAAPFGGV
                     KQSGLGREGGSVGIDEYLEVKYVAITVD"
     gene            complement(8515..9582)
                     /locus_tag="KFLA_RS32415"
                     /old_locus_tag="Kfla_6526"
     CDS             complement(8515..9582)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391550.1"
                     /locus_tag="KFLA_RS32415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6526"
                     /product="MsnO8 family LLM class oxidoreductase"
                     /protein_id="WP_012924075.1"
                     /transl_table=11
                     /translation="MFSPAPGLPVSAHSVLDVVPQPAGQSAAAALRETVEVAQAADDLG
                     FRRFWLAEHHGVRGFGSASPAVLAAVLAARTDRIRLGSGGILLGNHQPLLVAEQFAALA
                     AAYPSRVDLGVSEGAVSAPCTAAALGWSGDARETFPQRLDELCRFLRDGLPGRVPVGDV
                     RLTLAGLPPPVFVLANRPATAQLAAVRGLPVFLTASEATVAAAAAYRDTFEPTGPTGKP
                     YLGVSVGIVAADTDEEALNRLAEYVRVKHRLSTASLRATPAELLELLAPPLTGRERGRA
                     ERLLDDPGHIVGSRSTVASGLATLAASTGADEIMLTPLAYDGLVRSSILRTVAAALTRA
                     IRTVPRSAPHFVATA"
     CDS             complement(9595..9795)
                     /gene="allorf_6992193_6992393"
                     /locus_tag="allorf_6992193_6992393"
                     /protein_id="allorf_6992193_6992393"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MARDRDGSRWSWSSWPASRCRVELLERRERCLRRQRPGKSRRPPS
                     FGAGWGCGTWGWIPHVRSADR"
     CDS_motif       complement(9652..9795)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MARDRDGSRWSWSSWPASRCRVELLERRERCLRRQRPGKSRRPPSFGA"
                     /locus_tag="allorf_6992193_6992393_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9595..9651)
                     /prepeptide="core"
                     /locus_tag="allorf_6992193_6992393_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="2005.2"
                     /monoisotopic_mass="2004.0"
                     /core_sequence="GWGCGTWGWIPHVRSADR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MARDRDGSRWSWSSWPASRCRVELLERRERCLRRQRPGKSR
                     RPPSFGA"
                     /leader_location="[9651:9795](-)"
                     /alternative_weights="2023.2"
     CDS             complement(9699..9920)
                     /gene="allorf_6992297_6992518"
                     /locus_tag="allorf_6992297_6992518"
                     /protein_id="allorf_6992297_6992518"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSGKRLFCCCPRDGDWGLTAPRQQDLSRAASGGRLSGSGIQVWRE
                     TVTVPAGRGRRGRPPAVGSNCWNAENDA"
     CDS_motif       complement(9765..9920)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSGKRLFCCCPRDGDWGLTAPRQQDLSRAASGGRLSGSGIQVWRETVTVPAG"
                     /locus_tag="allorf_6992297_6992518_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9699..9764)
                     /prepeptide="core"
                     /locus_tag="allorf_6992297_6992518_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.70"
                     /molecular_weight="2265.4"
                     /monoisotopic_mass="2264.1"
                     /core_sequence="RGRRGRPPAVGSNCWNAENDA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSGKRLFCCCPRDGDWGLTAPRQQDLSRAASGGRLSGSGIQ
                     VWRETVTVPAG"
                     /leader_location="[9764:9920](-)"
     misc_feature    9899..9912
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.05"
                     /tool="antismash"
     misc_feature    complement(9899..9912)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: strong, score: 23.38"
                     /tool="antismash"
     gene            10001..12892
                     /locus_tag="KFLA_RS32420"
                     /old_locus_tag="Kfla_6527"
     CDS             10001..12892
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391549.1"
                     /locus_tag="KFLA_RS32420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6527"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_012924076.1"
                     /sec_met_domain="DUF4135 (E-value: 4.4e-105, bitscore:
                     350.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.4e-25, bitscore:
                     86.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSATAATAHPTAWWSAGLAPHESGAQRPAWAEYIERSTATTHE
                     PEAATGDWQHDLLRCLAPLLATARNDLLAAGHTGPVTDQFLQRLGHRLLKLSARTLVLE
                     LHRARVRGDLTGATPNERFLDFTHRLAGGSELADLLAEYPVLARILGEACRQSVAAHHE
                     LLTRLAEDRELLVTTLFHGRDPGELAGVDPGGDPHRGGRCTTVLTFADGRKVVYKPRPL
                     DLHEHFNQIVDWLNSRTAAALRTVRIVRRPGYGWMEFIEHAPCDDLAAVRRFYHRQGAL
                     LALLYVLDGTDMHHENLIAGGDQPVLVDVETLFHPAMASTGPLGQDPAHTALLSSVSRT
                     ALLPLMVVGEHGAADLSGIGGDDGVAPHEVVDWADAGLDSMHLVRRAGKNQYRDNRPTL
                     RGSVTEPRDHEVSLLAGFRSAYEAIARHRAELLGPAGLLTRCSADEIRYVPRPSRIYAT
                     LLDESTHPTALHDADGHSSLLDLLWDANQELRQVVPSELADLWSGNIPLFTTRPQTRDV
                     WASDGTRVPGLLRTEGLAAVEAKVAAMGEVDQDRQCWVISASLATRPAPVLHSSTATRP
                     GLGTAEADPEQLLAAATDIADEVMAQVLGDNGSQANWLGLELLDDHHWTILPMGAGLTN
                     GYLGTALFLAQTGVLTGATKYCELAYDAIRPIPQVLEVLAASPDAGQTVGAGLHGLGGI
                     SYGLSRLAELLDDSSLLSWLDLSLQLMENAASRSEGVPSYVEGAAGGLTAVQAIGSGPR
                     TTKLAAQYADELLAAVNLHLQQAEPAGFARGYAGIAWALGHYAAADSQYHHAARVAVER
                     AEQTTAANPGWCSGQAGTLLAGLRAGGPVDLDAYLRHATERPMLADLSLCHGELGAVEP
                     LLWLTERDHPAVAAVRRRRAGLVLAAVQQHGPQCGTPRAVPSPGLLTGLAGIGYGLLRL
                     GFHGQIPSVLLQEPARPAPITAPAGHQPTGETS"
     gene            12889..13101
                     /locus_tag="KFLA_RS32425"
                     /old_locus_tag="Kfla_6528"
     CDS             12889..13101
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KFLA_RS32425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Kfla_6528"
                     /product="hypothetical protein"
                     /protein_id="WP_012924077.1"
                     /transl_table=11
                     /translation="MTAQHPHDENLAQPATDLEGTDPLGPVTLPKRSKIGRRALALVGT
                     TSMAALAVQTLADGCSTFTTVGHEL"
     CDS_motif       12889..13023
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTAQHPHDENLAQPATDLEGTDPLGPVTLPKRSKIGRRALALVGT"
                     /locus_tag="KFLA_RS32425_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13024..13101
                     /prepeptide="core"
                     /locus_tag="KFLA_RS32425_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="2398.7"
                     /monoisotopic_mass="2397.2"
                     /core_sequence="TSMAALAVQTLADGCSTFTTVGHEL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTAQHPHDENLAQPATDLEGTDPLGPVTLPKRSKIGRRALA
                     LVGT"
                     /leader_location="[12888:13023](+)"
                     /alternative_weights="2416.7"
                     /alternative_weights="2434.7"
                     /alternative_weights="2452.7"
                     /alternative_weights="2470.8"
                     /alternative_weights="2488.8"
                     /alternative_weights="2506.8"
     gene            13220..16138
                     /locus_tag="KFLA_RS32430"
                     /old_locus_tag="Kfla_6529"
     CDS             13220..16138
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391546.1"
                     /locus_tag="KFLA_RS32430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6529"
                     /product="AAA family ATPase"
                     /protein_id="WP_012924078.1"
                     /transl_table=11
                     /translation="MRTHAPKVVGRDGEIEQLHDLLAAARSGHGGAVFLTGEPGIGKSR
                     LAAVGTTEALDHGMVTLRGRVVAIGTTVAFRPFSEALLSLIRRGEMPDPEVLGPYRRVL
                     ARLIPDWDDGTAETAVSAVVLGEAILRLLGTAGRDRGCLLVLEDLQGADPETLAVVEYL
                     LDNLEDQPIALIATVRSERCPAEVVAQLADQRGTATLTELRPLDRDQVRELAANRLEVG
                     PEAVPDQLADRLWTDSAGIPFIAEELLQEASRSGQLLAGGDGVVQVADDLRMTIPAAVV
                     HSINSRTDQLGPQSRELLVLAAVIGHRFPLSVVRQASAIDERQLLATLRAGLAAQLVGP
                     DEPVPDWYAFRHPLTAEALLAGLNPTERATLAGRCADAIELLHPGLPGEWSLMVAELAE
                     TGGNPARAARLFAEAGRRAFDEGSLGSAARLLDRAFTLLADDPDVEYRADVLGSLLLAL
                     GETGQFEHPAARPELVDHLASRGLDSRNVARLHVRLAEFNYSASRWSAAISHIGSARAL
                     LGPEAGDADLAPLEAIAAAVEMTRTSPGRLKSATELATRAAEAAQRANLPTVEADAWQL
                     LGILAREHDLEQSIRYFQRARQVATDNNMGLQRVVAHIFQAGTIYLADGDGTELETARQ
                     QALKIGAIPSAYDVDRILAQQAVLRAEYDVAAVKIEECLEVTRRLKLGRGAPYVLVTKA
                     MLAGHQCRRAAMEQTLAELAEYGERASHELPVSFGLARTFCALLEENRELAENEMAQAL
                     AYDAQNPSMFHLAGKNGVGLLLGVLAGRNSWEHLEAVMATAASRMRWNRQFVQLAHAVL
                     LGRDGRAEEASAMVDEALQTAEIYPMARHLGLRLVAEQAAADGWGDPVLWLRLAEEHFH
                     RADVPAVASACRSMLRQLGATVSQRRSGSDQVPAHLRQLGITTREYEVCLLLVDRIGNK
                     SIASRLHISPRTVEKHVASLMTKTRQPDREALSSFARTVLQD"
     misc_feature    16250..16259
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.18"
                     /tool="antismash"
     misc_feature    complement(16262..16280)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.58"
                     /tool="antismash"
     misc_feature    complement(16268..16281)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.69"
                     /tool="antismash"
     gene            16288..17538
                     /locus_tag="KFLA_RS32435"
                     /old_locus_tag="Kfla_6530"
     CDS             16288..17538
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391545.1"
                     /locus_tag="KFLA_RS32435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6530"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_012924079.1"
                     /transl_table=11
                     /translation="MAGKGSDMGKGTVGGGGTTMLRRINVAAVLDAVRRSAPAPLRVAE
                     LVERTGLARPTVAQAVDELLDNGWLQQHGPDSADRSLGRPAIRVSLRGRAAPVLGLDVG
                     PHRVTVGVSDLAGRKLSLVRRSGPGWTAQELLGVISEVITEALDEAEVPAEDIAAAVAA
                     SPGIVDEHTGRVQLAPSVPGWSSVDLVKHVRSLLDCPVMLDNDANLAALAIAAARGGTG
                     TLLAVQWGERLGAGIVIDGRLHRGTGAAGEIGFIATATDDVINPEDSRGPLERAVGSEA
                     IAALGRQAVLDHPDSRLAELGRDQLDTADVFAAAAERDPVAQAVVQQVARDFARALAPA
                     VLVLDPTAVVIGGGVARAGAVLLDAISDQLRLLTLNHPKLELSALAEDAVVTGAMRMAL
                     DEVWQRKLPTPALTTTA"
     gene            17585..18070
                     /locus_tag="KFLA_RS32440"
                     /old_locus_tag="Kfla_6531"
     CDS             17585..18070
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015060.4"
                     /locus_tag="KFLA_RS32440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6531"
                     /product="TspO/MBR family protein"
                     /protein_id="WP_012924080.1"
                     /transl_table=11
                     /translation="MSTWTESRPVRSAGVLVLLVAAVAAAALIGVLGVDGTAERYQQLQ
                     QPSWAPPSWLFGPVWTVLYAMIAVSGWLVWRRVGWSRALVPYAVQLLLNAAWTPLFFGA
                     GAIGPALVEIVLLWATIAWTVLTFARVRRSAAALLVPYWAWTTFATALNASIWWLNR"
     misc_feature    complement(18093..18103)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            18120..21473
                     /gene="lysX"
                     /locus_tag="KFLA_RS32445"
                     /old_locus_tag="Kfla_6532"
     CDS             18120..21473
                     /EC_number="2.3.2.3"
                     /EC_number="6.1.1.6"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: LPG_synthase_C (259-559). E-value:
                     6e-103. Score: 335.9. Matches aSDomain:
                     nrpspksdomains_KFLA_RS32445_LPG_synthase_C.1"
                     /codon_start=1
                     /gene="lysX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LPG_synthase_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391542.1"
                     /locus_tag="KFLA_RS32445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6532"
                     /product="bifunctional lysylphosphatidylglycerol
                     synthetase/lysine--tRNA ligase LysX"
                     /protein_id="WP_012924081.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 7e-101, bitscore:
                     335.9, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGQQAIPKWQQSAAGWVGLAVVSAAIWSFVAVPLHLVAPEVVKR
                     VEGVIDFTGIPAGHTFLSAVYLAVVGSALLRGKRAALLWVLWVFEGLTLVTQIAALGFI
                     SVRIANPNDPDLIAEFGRASIEDLEVGIVRVLVPALLIVLLWRIRDSFPARLAPGSRRV
                     AIGVLVTGLLISIAVSIALTQVVPNTLQGQKEKIGWAVFSAFGQSRARMGSGHEGHAWV
                     GLTVGFLSAASLVIAFWIFLRSVRRVRYLSQAEELQVRRLLLQYGERDSLGYFATRRDK
                     AVVFAPGNDAAIAYRVVNGVSLASGDPLGDPAAWPGAIEQWLAEARIYGWSPAVLSASE
                     EAARAYVDAGLRALAMGDEAIIDVADFSLEGRTMRPVRQAVTRVQRAGYHAQVVRHGDL
                     APDDLAQYVELAERWRGARTERGFSMALGRLGDAADARCVMVIARDAGGAVRGLLSFVP
                     WGVRGVSLDLMRRDPESVNGLMEFMVTALVDACGDLGVHRISLNFAMFREIFSDAERVG
                     AGPVLRLTNALLTAASRFWQLESLYQSNEKYLPRWSPRLICYSRGASLAQVLLAAGTAE
                     GFLPAPRPWTRVDARSTADRNAIAVGDDGRFAITVQEQEDELLRPALPDRRLTEQERIR
                     RAKSSAMVAEGIDPYPVSVPRTETLERILALHQNLPPDHHTGHHVSVTGRVMRLRDHGN
                     LAFAQLQDGLDQLQVMLAAGTCPAEDLRNWDRFVDIGDHVSVTGEVVTSRRGELSVAVT
                     GWTMAAKCLHPLPDKRKGFTDPEARVRQRHLDLVTNPDALRMLRHRSTAVRALRHGFEA
                     RGFVEVETPMLQAVHGGANARPFVTHINAYDTDLFLRIAPELFLKRLGVGGLGKVFELN
                     RNFRNEGADATHNPEFTSVEAYQPYADYHVMRELTRELLLETAVAVFGKAVVQRDGAEL
                     DISGDWPVVTVHDAVSRAAGVTIDPGTPVSRLREICAQHGVRAGFDLSAGELVLELYDE
                     LVEPRTTLPTFYTDFPLETSPLPRGHRTDPRLAERWDLVAFGAEIGTAYSELVDPVEQR
                     RRLTEQSLKAAAGDPEAMSLDEDFLAALEYALPPTGGLGLGVDRILMMLTGQNIRATLA
                     FPFVRPTPRS"
     aSDomain        18897..19796
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KFLA_RS32445_LPG_synthase_C.1"
                     /evalue="6.00E-103"
                     /label="KFLA_RS32445_LPG_synthase_C.1"
                     /locus_tag="KFLA_RS32445"
                     /protein_end="559"
                     /protein_start="259"
                     /score="335.9"
                     /tool="antismash"
                     /translation="RRLLLQYGERDSLGYFATRRDKAVVFAPGNDAAIAYRVVNGVSLA
                     SGDPLGDPAAWPGAIEQWLAEARIYGWSPAVLSASEEAARAYVDAGLRALAMGDEAIID
                     VADFSLEGRTMRPVRQAVTRVQRAGYHAQVVRHGDLAPDDLAQYVELAERWRGARTERG
                     FSMALGRLGDAADARCVMVIARDAGGAVRGLLSFVPWGVRGVSLDLMRRDPESVNGLME
                     FMVTALVDACGDLGVHRISLNFAMFREIFSDAERVGAGPVLRLTNALLTAASRFWQLES
                     LYQSNEKYLPRWSPRLICY"
     misc_feature    complement(21537..21552)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            21567..22517
                     /locus_tag="KFLA_RS32450"
                     /old_locus_tag="Kfla_6533"
     CDS             21567..22517
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391541.1"
                     /locus_tag="KFLA_RS32450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_6533"
                     /product="hypothetical protein"
                     /protein_id="WP_012924082.1"
                     /transl_table=11
                     /translation="MRKMVSVALGVALLGLATGCGNGDDAADDAPTSSATTTSVPTASA
                     PASAPSAPASTPAGPVTGAQYQAQLAEADRRIAAEVRGLTGANSATNLQNAILSLSERL
                     TTEATMLGALQVQPHVAAAHKTLQTRLRAAATALSAHDTVGTDAKCGGVVYTSQTVQRK
                     LTADLTAAVTPLAKLGLRFGTSLPKVEPEPADQRPSNGDVLVRSGPRGSGRLQVKNGTA
                     QDVAVAVVTDGKPPAKPHLLVYVQAKKTATISRIGGQYHLYAKSGTDWNPKRRQFSKDC
                     SFLKFDQGFGRNEGWRVDLQPSALGNASTSDVAPF"
ORIGIN
        1 gccctcgctc gcggccgccc ggcagaccat gcgccctgcg ctgccggaca atgcgaccgt
       61 ccagcaactg gaagcctggt tggagctggg ctcgctctgc caggactccg acttccggga
      121 ccttctgcgg cagctcgtga agaatgtgcc ggccgacggc gtgccgcgtc ccgatgccgt
      181 cgctgtcgtc cgcgaccgag tggcacagct cgacggcctc tcgcccgact cccctgccgc
      241 agccgcgatc gtcgtcgagc tcggtccact ggacatcgac cacctccggc tggcatcgga
      301 cccgcgcagg cagcgctacg tcgagctctt ggcagtcctc aacgactggc ccgccccaac
      361 cgacccaacg cccgccctga actggtacct ggccgcagcc cgcgcgtgaa cctccggcct
      421 tcggcggagt accactgcag ggccaggacg acagccagca agatctcgac cacgtcgccg
      481 ccgtagtaca tgaccttcgc gccgacagcc aggtcagcag cagcgaacgt ggtgcccggc
      541 ggcggagaag cgtacagcga cttcgccagt acggcgtgcg ccgcgccggc cagaacgacc
      601 gtcgcggcgc gcggcacgag gccgtagcgg cgccgaacgg gatccagctg gcagatgacg
      661 aaggcgaaca gcagtccgct cacgatgacg tgcccgtgaa ccaccgcgtg cagccagggg
      721 cgttcctgcg acgcagcgaa cagcggagtc cggtagagcg cccagagacc gccaacctcg
      781 aggacagcga ccactggaag aagctgcacg aagctcgacc acctggagtg cgcgagagcg
      841 agcaaggatt gccgagcccg gccagggcgg agtacgcgga gagcgagggt cagcgggcgg
      901 gccagcacaa tcagcagcgg cgcaagcatg ccgatgagca ggtgctgggt catgtgagcc
      961 gtgaacgctc gacccggcag cggcaaggcg aaggccgcag tgagtccgag cactccaccg
     1021 gcgaagcaca ggaaccgccc gacggaccag gtgtccccgc gccgctgcag ccgctgcacc
     1081 gcccacgcgt acacgatcac caggaccaac gccgtcagca gggcagcgaa ggtcgccagc
     1141 ccggtcgcct gatggtcgtg cgagtgggtc atggccgagt gcgcccggcg cggatcagca
     1201 ggacgccggc cacgaccatc aggaccgcca gcacgttcca ggtccagtcg tacagcgtga
     1261 ggtcgacctg gtagcggatc tgatgcagat cgagcagctt gtgctggacg gtgccgtcgt
     1321 acaactggaa ggcgcccgcg cccagcagga tgccgccagc cagactgcgg ccgaccaggc
     1381 ccgcacgccg gcgcagatcg gccaccatga ccagcccgat gaccaccgcg aaccacccga
     1441 aggcatggaa cagcccgtcc gagacgagcc cggctgcggg cgtcgaccgg tcgtagaagt
     1501 ggtgccagtg cagcaactgg tgaaacacgg tctcgtcgac gaacgccgcg atcccgatgc
     1561 cgatcagcac cccggcccag acggaccgag tcggcagcag cacgccgtac tccggtggag
     1621 gctgcacctg ggaacgttgg gccggtgggc gggcggtgga catcggaaca cccttcacgc
     1681 ggggacggtt gatcgccggt acccagatcc ccgggcgcta tccgagccag ctgcctgccg
     1741 gcgctagagg atgcgcaggg tcagcggcgt gggcggaggg cggtgaggtg ggcgtcgagc
     1801 agcaactcca gccgtttgcg gccgaaggtt cgcggatcca ccagggcttg caccacgaga
     1861 ccgtgggtga aggcggccag accggcggcc aggtccatgg catcgcccgt gatcaggtcg
     1921 ccatcgttct gcgcctgaat gaccagcggc ttcagccgcg ttcgccagcg gcggtagcga
     1981 gcttgctcca gcgcagccaa ctgagggtcg gccagcgcga catcccagga gctgacccag
     2041 acccggttca gttcggtcgt ttccgcagtt agcggcagca ccgcgatcag agcagtccgc
     2101 agatcggtgg tgtccgggac cagggcctgc gtccgctgct cggcaacctc cagggcgtgc
     2161 agtaccagcg cctgcttgga cggaaagtag tgggtgacca atccggtgga cccgcccatc
     2221 gccgccgcca ccgcgcgcag cgtcaggccg ccgaacccgt ccgcggcaac gactttccac
     2281 accgccgccg acacgtcacg gcggcgcgcg tcgtgatccg ttttcgccgg catgcgtcca
     2341 gtgtacgtac caaacaattg ttatgtatgg tggggcggtc cagcactccc gggtcctgag
     2401 gagacacgat gttcgctgca acgatcgccg acaacgccga gttgcggccg ctcgagccct
     2461 ggcaggccgc cgagttccag gcccatgtcg acaaggctcg aacgaacctc tccccctact
     2521 tgccgtgggc ggtgactgtc gtcgacgacc gaacagcacg tgagttcctg cagcgctatg
     2581 ccgagcgcca ggctgcggac gagggtcgca tctacggcat ctggctggcg gacgaactcg
     2641 tcggcggact gctgttccgc accttcgaca ccgatgacgg cagttgcgag atcggcgtct
     2701 ggctggccgg ccacgccgag gggcgcggtc tggtcacccg ctcggcgcag ctcctgatcg
     2761 attgggcgct cggcgtccgg ggcctgagcc gggtcgagtg gcggtgtgtc ccgtcgaaca
     2821 cccgcagcat cgccgtcgcg cgccgcctgg gaatgacaca cgagggcacc ctccggcagg
     2881 cctttcccta ccgcggggaa gcgcacgacg tacagacctg gtcgctcctg cgcaccgaat
     2941 gggaggaccg ctcgcgggag tagcccggtt cggaggcata ctcgacttcc gtgactgggg
     3001 cacggggatg gacgttggct gcgttctgcg cggtggtggc agtactgctc ggcagctgtg
     3061 gcggctcctc ggctccgccc agcgtccagg actcgcccac gccgaccgtc tcggcgagca
     3121 caccggctca gccgtcgtcg aagcccagca ccaccccggt gcgccggcct ggtgagtccc
     3181 gggcgcgaac gctgatgccg atcgtgcagc acggtccccg ggacaagccg cggatcgcac
     3241 tgaccttcga cgccgacctc acgaccgcaa tgcgccgccg gctgcacagc ggtcaggtga
     3301 agtcgtacta caacgaggca ctgatccagc acctgcgcga cctgagggtc ccggccacct
     3361 tgttcctcac cggcctgtgg atggagcagt acccggaccg gacccgcgag ctggccgcgg
     3421 acccgctctt cgagctcgcg acccacagct acgaccaccg tgccttcacc aagcgctgct
     3481 acacgctcgg caccgtcccc cgcgccggca tgctcaccga cgtacgccgg gccgtcacca
     3541 tcctggacga gctggacccg caggcgaccc gctggttccg gttccccggc ggctgctacg
     3601 acggcaccgc cctgcacgag ttggctccgg ccgctgtcac cgcggtcggc ctggacgttc
     3661 cgggcgccga cggcttcgcc aagtcgtccg agtcgatcgt cggccaggtc ctgcagaacg
     3721 cgcgcaacgg ctcgatcgtc gtcctgcaca tgcacggcgg cgacaacgcg ccgctgaccg
     3781 acgaggcgat tccctcgatc gtgaaatcgc tgcgtttgcg gggctacgag ttggtcaccg
     3841 tgacggaact gatggccggc tgaagccgtc acaacctgcg gtccggcgag tggcggtggc
     3901 gcgacgcccc gtccggggtg gcagtctggg ctgacgacgg gccaacggtc cggcgctacg
     3961 agacagggac ggtgggcttt gacgacgacc gagtcgcggt cacggggccg gagcctgcgt
     4021 ggcaacgcgc tgggagttgg tgcgggcacg gcgatcggcg tcgcctccac cgccccggcg
     4081 tactcgctgg cagtgtcggt gggactgctg gctgtgtaca ccggcgccgc ggcaccgctg
     4141 gtgctggcgg tcagcgcgat accggtcgta ctggtcgcgc tctgcttccg ggagctgaac
     4201 cgggccgagc cggactgcgg tacgacgttc ccgtggaccg agaaggcgtt cggcctgagc
     4261 gtcggccgga tggtcggctg gaccacggtg atggcctgcg tcctggtgat gagcaatctc
     4321 gcccaggtcg ccgccgtcta cacctacgca ctgctcggcc tggaaaccgc tgaggagtcc
     4381 cggctggcac aggccgggct gggcacggtg ttcatcctcg gcatggccct gctcgcgtac
     4441 cgcggcatcc gggtcgccgc aggcacccag ctgttgctgc tgtcggtcga gctggtcgcg
     4501 ctgatctggt tcgtcgtcgg cgcgttccgg gaggccggca ccgtcagcat ccccgcgttc
     4561 tcggacaccg gtgacggagc gtgggcggcc ggcgtactgg tcgctgtctt cctctactgg
     4621 ggctgggact cgtcgttcag cgtcaacgag gagtcccgca acccacgcag tactccggcc
     4681 atcgccgccc tcgtcgcgaa cggcatcctc gtcgtcctgt acgtcgtggt cgcctgggcc
     4741 gccgtcgcgt acgccgggac cggccagctg gcggagatcg ccgacgacga cttcctggcg
     4801 gtgctcggcg ccgacctgct cggcacggcc ggcggcaagc tgctgatcgc cgcggtcctg
     4861 gtgtcggcgc tggcctcgac gcagaccacg atcctgccga ccgcccggac gatgctgtcg
     4921 atggcccggc gggacgcgtt cccgggccag ttcgcgcgga tctcggcccg ctaccagacc
     4981 ccgagcgtgt cgacctggac gttcgcgacc gccagcgtgc tggtgtacgt cgtgctggtg
     5041 ctcacgtcgg acgccgtact ggccgactcc gtggccgcgg tgtccatcct ggtctcgctg
     5101 tactacctgg ccacggctct ggccgtcccg gtgtacttca gcggcgagct ccgcggccgg
     5161 atggtccagc ggctggtggt gccggtgctg gcgaccgtgt cgttcgcgac ggtgctcgtg
     5221 ctggcggtgg ccgacgtcgg caccggcccg ctggttgtgg tcggtgtgac catggtggtg
     5281 ggcgcggcgg tgatgttctc gatgaagccg ccggccgaag gggagggacg acgatgagcg
     5341 accgccggat gcgcagtgtg gggatcacgc tcggtctgac cgcgctggtc gccgcctcac
     5401 tgaccgggtg ctccagcgac gacgaggacc agccggacta cgcggcgatc tgcgtcgacc
     5461 cggagaccga gcagcggacc agcgacgaga actgcaagga cgagcgcgag tacaacggct
     5521 ccggcgcggg attcttctgg ttctacatgg ccacccgcag cggagtgctc gtaccgccga
     5581 tcggtggccg ctacccggcc ggctccggca cctacaccgt cccgcgcacc ggcaccggcg
     5641 gcgcggcgcc ctcggtccgg cgcggcgggc tgaacccggg cggcggtgac atcggcacca
     5701 tcacccgggg cgggttcggc aagtccggca aggggagctc tggcggctga tgtggcgaca
     5761 cgcgatcaag ccgcggccgg actggcgcga caaggtcgtc gagcagggcc tggtctaccc
     5821 gatgaccgag ctgcccgacg gcaccgagcg cccgtactgg aacgagagcg cgtggtacga
     5881 ggtgaccatg gaggaggtgc tgcacctcga gcgggtcacc gaggagctgt acgagatgtg
     5941 caagcacgcc gcgtcggtga tggcggccgg tgaccggttc agcgacgccc agctcgggct
     6001 cgccccgggc acgttgccgc tggtgcagca gtcgctgaaa cgcgacgacc tgtccgtgta
     6061 cgcccggttc gacctggtct ggaacggcgt cgagccgaag atgctggaga tcaacgggga
     6121 caccccgacc gggctgctgg agtccgcggt gatccagtgg aactggctgg aggacgtctt
     6181 ccccgacgcc gaccagtgga actcggtgca cgaccgcctg gtcaagtggt ggagcgagca
     6241 gctcgccgcc ggccggttgc cgggcaacga ggcgcacttc ttcaactccg gcgccgagac
     6301 caccggcgag gaggcgatga cggtggccta cctgcgcgac acggcggcga tggccgggct
     6361 ggcgacgtac gggcacgaga tcgaggacct gggctgggag tcggcgcagc gggcgttcgt
     6421 cgactggggc gggcggaaga tccggaccgc gttcaagctg tacccgtggg aggacatgct
     6481 cgacgacgag ttcggccgct acctgctggc cggcgtcgaa cgcgagccgg tgcagtggat
     6541 cgagccgatc tggaagacga tgctgtccac caaggcgatc ctgccggtgc tgtgggagct
     6601 ctacccggac cacccgaacc tgctgccggc gtacttcgac caccccggcg acctgctcga
     6661 gtgggtggcc aaaccgctgc acggccggga gggcggcaac atccggatcc acaccatcgg
     6721 cggcgacgac cacgtgcacg acggcccgta cgacaccggc acgatggtct accaggagtg
     6781 gagcccgctg ccgtcgtacg aggggaaccg ggccgtgatc ggcagctgga tcgtcgacgg
     6841 ggcggccgcc ggcatgatgg tgcgcgagtc cgacgggccg atcaccgact actacgcccg
     6901 cttcgtcccg cacgccatcg gcaccgcgcc gcgccccgac gaggagacga tcaagcagtg
     6961 gctgacggag tgatcagtcg acggtgatcg cgacgtactt gacctccagg tactcgtcga
     7021 tgccgacgct gccgccctcg cggccgaggc cggactgctt gacgccgccg aacggcgccg
     7081 cgggattgga gacgatgccc tggttgagcc cgatcatgcc ggtctccagc ttctcgcaga
     7141 cccgcagcgc gcggctgagg tcgttggtga acaggtagga gaccaggccg aactcggtgt
     7201 cgttcgccat cgcgaccgcc tcgtcctcgg tgtcgaaggc ggtcagcggt gcgaccgggc
     7261 cgaagatctc ctccttctgc agccgggccg accgtggtac gtcggtgagc acggtcggcg
     7321 ggtagaaata acccttgccc tcggcaactt cggcgccggt gagcacgcgg gcgccctgct
     7381 gcaccgcgtc gtcgaccagc tccttcacct tgtcgcgctg ctcggcgtcg atcagcgggc
     7441 ccacctcgac gccgtcctcg gtgccgcggc cgaccctcag cgccgacatc cgctcggtca
     7501 gcctggtcgc gaagtcgtcc agcaccgacg agtgcacgta gatccggttg gccgcggtgc
     7561 acgcctcgcc gccgttgcgc atcttggcct gcagcgcgcc ctcgaccgcc ttgtccaggt
     7621 ccgcgtcggg gaagaccagg aacggcgcat tgccacccag ctccatgctc gtgcgcagca
     7681 cctgttcggc cgactgctcg atcagcttcc ggccgacctg cgtggagccg gtgaacgaga
     7741 gcttgcgggc ccgcgggtcg cggatcagcg gctccatcac gccgccggag tcgctggtgg
     7801 tgaccacgtt gagcacgccg gccggcaacc cggcctcggt catcagctcg gccagcttca
     7861 gcatcgacag cggcgtctgc gcggccggct tgatcaccat cgtgcagccg gccgcgaccg
     7921 ccggcccgat cttgcgggcg cccatcgcgg ccgggaagtt ccacggcgtg atcagcaggc
     7981 acggcccgac cggctgccgc gtcaccagga accggccctt gccgttcggc gcgacctggt
     8041 agccgccgtc gatccgcacc gcctcctcgg cgaaccagcg gaagaactcc gcggcgtacg
     8101 cgatctcgcc cttggactcc gcgaccggct tgcccatctc cagcgtcatc agcagcgcca
     8161 gctcgtcggc gcgctcggtc atcagctcgt acgtccggcg caggatctcg ccgcgctcgc
     8221 gcggagcggt ggcagcccag tccgcctgtg cggcgacggc cgcgtccagt gcggccacac
     8281 cgtcggccgg accggcgtcg gcaacctcgc acaacgtcgt accggtggct gggtcctcga
     8341 cggcgagagt cctaccgctc tccgccgctc gccacttgcc accgacgaac agctcggtcg
     8401 ggcactcctg gacgacttcc tgctcgcgcg acatcagctc tgcctttccg tagtggggca
     8461 gtacccacct taggtcgggg cggtcgagcg ttgggcgcga tcaggcggtg gcgatcaggc
     8521 ggtggcgacg aagtgcgggg ccgagcgcgg cacggtgcgg atcgcccggg tcagagccgc
     8581 cgcgaccgtg cggaggatcg aggagcgcac cagaccgtcg tacgcgagtg gggtgagcat
     8641 gatctcgtcc gcgccggtgc tggcggccag ggtcgccagc ccggaggcca ccgtcgagcg
     8701 tgaaccgacg atgtgccccg ggtcgtccag cagccgctct gcccgcccac gctcgcggcc
     8761 ggtgagcggc ggcgccagca gttcgagcag ctcggccgga gtggcccgca gcgaggccgt
     8821 gctcagccgg tgcttcaccc ggacgtactc cgccagccgg ttcagcgcct cctcgtcggt
     8881 gtccgcggca acgatcccga cggacacccc gaggtacggc ttgccggtcg gcccggtcgg
     8941 ctcgaacgtg tcccggtacg ccgccgcggc cgccaccgtc gcctccgacg cggtgaggaa
     9001 caccggcagc cctcgtaccg cggccagctg cgccgtcgcc ggccggttcg ccaggacgaa
     9061 caccggtggt ggcagcccgg ccagcgtgag gcggacgtct ccgacgggaa cccgtccggg
     9121 cagaccgtca cgcaggaacc ggcagagctc gtccagccgc tgcgggaagg tctcccgcgc
     9181 gtcaccggac cagcccagag cggccgcggt acaaggtgcg gagacggcgc cctcgctgac
     9241 gccgagatcg acccggctcg ggtacgccgc cgcgagcgcc gcgaactgct cggcgaccag
     9301 cagcggctgg tggttgccca gcaagatccc gccggacccg agccggatcc ggtcggtccg
     9361 ggccgccagc accgcggcga gcaccgccgg cgacgcgctg ccgaagccgc gcaccccgtg
     9421 gtgctccgcg agccagaacc ggcggaagcc gagatcgtcg gccgcctggg cgacctccac
     9481 ggtctcccgc aacgcggcgg cggcggactg gccggccggt tgcggcacca cgtcgagcac
     9541 cgagtgggcg gagaccggga gtccgggagc tgggctgaac acctgcccac cgtgtcacct
     9601 gtccgccgat cgcacatggg ggatccaccc ccatgttccg cacccccacc cggcgccgaa
     9661 agatgggggc cgacggctct tgccgggccg ttgacgcctc aggcatcgtt ctcggcgttc
     9721 cagcagttcg acccgacagc gggaggccgg ccacgacgac cacgaccagc gggaaccgtc
     9781 acggtctctc gccacacctg gattcctgac ccggaaagcc ttccaccaga ggcggcccgg
     9841 gacaggtcct gctgccgcgg ggcggtcaac ccccagtcac cgtcccgcgg acagcagcaa
     9901 aacaagcgtt tgccggacac gtacgtcgaa gcgaacgctt gcgggaatat gggggttcca
     9961 tacccatgtc ttctcgcgcg cctgctgcca cgctgtcggc gtgctcgact cagcgacggc
    10021 ggcaaccgcc catcccacgg cctggtggtc cgctgggctg gctccgcacg agtccggcgc
    10081 gcagcgcccg gcctgggcgg agtacatcga gcgcagtacc gccaccaccc acgagccgga
    10141 ggcggcaacc ggggattggc aacacgattt gctccgctgc ctcgctcccc tgctcgccac
    10201 cgcccgcaac gacctgctcg ccgccggaca caccggcccg gtcaccgacc agttcctgca
    10261 acgcctgggc caccgcctgc tcaagctgtc cgcccgcacc ctggtcctgg aactgcaccg
    10321 cgctcgggtc cgcggcgacc tgaccggcgc caccccgaac gaacgtttcc tggatttcac
    10381 ccaccggctc gcaggaggga gcgagctggc ggacctcctg gccgagtacc ccgtcctggc
    10441 ccgcatcctg ggcgaggcgt gccggcagtc cgtagccgcc caccacgaac tgctgacccg
    10501 cctcgccgag gaccgcgaac tgctggtcac cacgctcttc cacggccgcg acccgggcga
    10561 gctcgccggt gtggatccag gcggcgaccc tcaccggggc ggtcgctgca cgaccgtcct
    10621 cactttcgcc gacggtcgca aggtcgtcta caagcctcgg cccctggatc tgcacgagca
    10681 cttcaaccaa atcgtcgact ggctgaacag caggaccgcc gcggccttgc gcaccgtacg
    10741 gatcgtccgc cgccccggct acgggtggat ggagttcatc gagcacgcgc cgtgcgacga
    10801 cctggccgcc gtacgccgct tctaccaccg ccaaggcgct ctgctggctc tgctgtacgt
    10861 gctcgacggc accgacatgc accacgagaa cctcatcgcc ggcggcgacc agccggttct
    10921 cgtcgacgtc gagacgctgt tccatccggc catggcgagc accggtccgc tcggtcagga
    10981 tccagcccac accgccttgc tcagctcggt ctcccggacc gcactgctgc cattgatggt
    11041 ggtcggagag cacggtgccg cggatctgtc cggcatcggc ggcgacgacg gcgtagctcc
    11101 ccacgaggtc gtcgactggg cggatgccgg actcgactcg atgcacctcg tacgccgcgc
    11161 cggcaagaac cagtaccgcg acaaccgacc tactctgcgc gggtcggtga ccgagcccag
    11221 ggaccacgaa gtctctttgc tcgcaggctt tcgcagcgcg tacgaagcca tcgcccggca
    11281 ccgcgccgag ttgctcggtc cagctggcct gctcacccgg tgctcggcag acgagatccg
    11341 ctacgtcccg cgtccttcgc ggatctacgc caccctgctc gacgagtcga cccatcccac
    11401 tgcgttgcac gatgccgacg gccacagctc actgctcgac ctgctgtggg atgccaacca
    11461 ggagctgcgc caggtggtgc cgtccgagct cgcggatctc tggtcgggca acatcccgct
    11521 cttcaccacg cgcccgcaaa cccgtgacgt ctgggcttcc gacggcaccc gggtcccggg
    11581 cctgctgagg acggaaggcc tggcagccgt cgaggcgaag gtcgcggcga tgggcgaggt
    11641 cgaccaggac cgccagtgct gggtgatctc cgcgagcctc gccactcgcc ccgcaccggt
    11701 gctgcactcg agcaccgcca cccggccggg actcgggacc gccgaagcgg atccggagca
    11761 gctgctcgcc gccgccaccg acatcgcgga cgaggtgatg gcccaggtcc tcggcgacaa
    11821 cggcagccag gcgaactggc tcggcctcga actgctcgac gaccaccact ggacgatcct
    11881 tcccatgggc gccgggctca ccaacggcta cctcggaacc gcgttgtttc tggcccagac
    11941 cggagttctc accggcgcga ccaagtactg cgaactggcg tacgacgcga tccgcccgat
    12001 cccccaggtg ctcgaggtct tggcagcgag tcccgacgcc gggcagaccg tcggcgccgg
    12061 cctgcacgga ctgggcggga tcagctacgg cctcagcagg ctggccgaac tgctcgacga
    12121 ctccagcctg ctcagctggc tggacctgtc gctccagctg atggagaacg cagcgtcccg
    12181 ttccgaaggc gttccgagct atgtcgaagg cgccgccggg ggcctcaccg ctgtgcaggc
    12241 gatcggcagc ggtccacgga cgacgaagct tgccgcccag tacgccgacg aactgctcgc
    12301 cgctgtcaac cttcacctcc agcaggccga gccggccggc ttcgcgcgcg gctacgcggg
    12361 aatcgcttgg gcgctgggcc attacgccgc ggcagattcg cagtaccacc acgctgcccg
    12421 agtcgcggtt gagcgagccg agcagaccac cgcagcgaat ccgggctggt gctccggcca
    12481 ggccgggacg ttgctcgccg gtctgcgcgc cggtggaccg gtcgacctcg acgcctacct
    12541 gcgccacgcc accgaacgtc cgatgctcgc cgacctgagt ctgtgtcacg gcgagctcgg
    12601 cgcggtcgag ccactgttgt ggctgaccga acgcgatcac ccagccgttg cggccgtccg
    12661 gcgccgccgg gccgggctgg tgctcgccgc agtacagcag cacggaccgc agtgcggcac
    12721 gccgcgcgcc gttccctccc ccggtctgct gaccggcctg gcgggaatcg gctacggcct
    12781 gctgcgcctc ggcttccacg ggcagatccc gtccgtgctg ctgcaagaac cggcccggcc
    12841 ggcgcccatc acagcgccgg cgggccacca accgacaggg gagacatcat gaccgcccag
    12901 cacccgcacg acgagaacct cgcccagccc gccaccgacc tcgaaggcac cgacccgctc
    12961 ggtcccgtca ccttgccgaa gcgcagcaag atcggtcgcc gcgcgctcgc actcgtcggc
    13021 accaccagca tggcggcgct ggcggttcag actctcgccg acggctgctc gaccttcacg
    13081 actgtcgggc acgagcttta gcgcctgccg ggcggccgga tggatggatc gggcaacgat
    13141 ccgatcaaac gtctgatgca cttccagccg accagccgat ccgcctgcga tccgacctgt
    13201 ccacgattag agtgcaggga tgcggaccca tgcgcccaag gtggtcggca gggatgggga
    13261 gatcgaacag ctccacgacc ttttggcggc tgcccgttcc ggccatggcg gtgctgtctt
    13321 cctgaccggc gagcctggca tcggcaagag ccggctcgcc gcggtaggca ccaccgaggc
    13381 gctggatcac ggcatggtca ctctccgggg ccgggtcgtc gccatcggta cgacggtcgc
    13441 cttccggccg ttcagcgaag cgctgctgtc gttgattcgc cggggagaga tgcccgatcc
    13501 cgaagtgctc gggccgtacc gacgggtact cgcccggctg atcccggact gggacgacgg
    13561 aaccgccgag accgctgtct cggcggtcgt gctcggcgag gcgatccttc ggctgctcgg
    13621 cacggccggt cgcgatcgcg gctgcctgct cgtcctggaa gacctgcagg gcgcggatcc
    13681 ggaaacgcta gccgtcgtcg agtacctgct ggacaatctc gaggaccagc cgatcgcgct
    13741 gatcgcgacc gttcgctccg aacgctgccc cgccgaggtc gtggcgcaac tggccgatca
    13801 gcgaggcact gccacgctga cagaactccg tcctctcgac cgggaccagg tccgcgagct
    13861 cgcggccaac cggctcgagg tcgggccgga agccgtcccg gaccagctcg ccgatcgcct
    13921 ctggaccgac agcgccggca tccccttcat cgccgaggag ttgctgcagg aagccagcag
    13981 gtcgggccaa ctgctggccg gtggcgacgg tgtggtgcag gttgccgacg acctccggat
    14041 gaccattccg gccgctgtgg tgcacagcat caacagccgg accgaccagt tgggtccaca
    14101 gtcccgagag ctgcttgtcc tggcagcggt gatcgggcac cgtttcccgc tgagcgtggt
    14161 ccggcaagcc agtgcgatcg acgaacggca actgctcgcc accctgcggg ccggcctggc
    14221 cgcacagctg gtcgggccgg acgaaccggt tcccgactgg tacgcgtttc gccatccgtt
    14281 gaccgccgag gcactgctcg ccgggctgaa cccgaccgag cgtgcgacgt tggccggccg
    14341 gtgcgccgac gcaatcgagt tgctccaccc cgggctgccg ggcgagtggt cgttgatggt
    14401 cgcggaactg gccgagaccg gcgggaaccc ggcacgtgcg gcacggttgt tcgccgaggc
    14461 agggcggagg gccttcgacg agggttcgct cggcagtgcg gcgcggctgc tcgatcgcgc
    14521 tttcaccttg ctggccgacg atccagatgt cgagtaccgt gcggacgtgc tgggctccct
    14581 gctgctcgcg ctcggcgaga cagggcagtt cgagcacccg gccgcccggc cggagcttgt
    14641 cgaccacctg gcaagtcgcg gtctggacag tcgcaacgtg gcccggcttc acgtccgtct
    14701 cgcggagttc aactactccg ccagtcgctg gtccgctgcg atttcgcaca tcggctccgc
    14761 ccgagccctg ctcggaccgg aggccggcga cgccgacctc gccccgctgg aggcgatcgc
    14821 ggcggcggtc gaaatgacca ggaccagtcc gggccggctc aagtcggcca ccgagctggc
    14881 cacccgggcc gcggaggccg cgcaacgcgc gaacctgccg acggtcgaag ccgatgcgtg
    14941 gcaactgctc ggcatcctcg ctcgggaaca cgatctcgag cagtcgatca ggtacttcca
    15001 gcgcgctcgg caggtagcca ccgacaacaa catggggctg cagcgcgtcg tcgcgcacat
    15061 cttccaggcg ggcaccatct acctcgccga cggtgacggc accgagctgg agacggccag
    15121 gcagcaggcg ctgaagatcg gggcgatccc gagcgcttac gacgtcgacc gaatccttgc
    15181 ccagcaagcc gtgctcagag ccgagtacga cgtggccgcg gtgaagatcg aggagtgcct
    15241 ggaggtcacc cggcggctca agctcggccg cggcgcgccg tacgtgctgg tgaccaaggc
    15301 gatgctggcc ggccatcagt gccggcgcgc cgcgatggag cagaccctcg ccgaacttgc
    15361 cgagtacggc gagagagcgt cgcacgagct gccggtgtcc ttcggactgg cgcggacctt
    15421 ctgtgcgctg ctcgaggaga accgcgagct cgccgagaac gagatggccc aggcgctggc
    15481 ctacgacgcc cagaacccga gcatgttcca tctggcgggc aagaacggtg tcgggctcct
    15541 gctcggcgta ctcgccggcc gaaacagctg ggaacacctt gaagcggtga tggccaccgc
    15601 ggccagccgg atgcgctgga accggcaatt tgtccagttg gcgcacgctg tcctgctggg
    15661 acgggacgga cgcgccgagg aagcctcggc gatggtcgac gaggcgctgc aaaccgccga
    15721 gatctatccg atggcacgcc acctcggtct gcggctggtg gccgagcagg cggcggccga
    15781 cggatggggc gatcccgtgc tctggctccg gctggcggag gagcacttcc accgcgccga
    15841 cgtaccggct gtcgccagtg cctgccggag catgttgcgg cagctcgggg cgaccgtgtc
    15901 gcagcggcgg tcgggcagtg atcaggtgcc ggcgcatctg cggcagttgg ggatcaccac
    15961 ccgggagtac gaggtctgcc tgttgctggt ggatcggatc gggaacaagt cgatcgcgtc
    16021 gcggttgcac atctctcccc gtaccgtgga gaagcacgtg gcgagtttga tgaccaagac
    16081 gcggcagccg gatcgtgagg cgttgagcag cttcgcgcgg acggtgttgc aggactgatc
    16141 ccggggtccg cgcgtgtgct caggcggtgg gtgcccggtc ggtgataggt gtcgacgcac
    16201 ggacctcagg gggtggccgc ccaccccgcg gcgcgcgtcg ttccgtcgat aatttatgaa
    16261 cgctcgcttt atatatagga tgggcgagtg gcaggcaagg ggtcggacat gggcaaggga
    16321 acggtcggcg gcggcggtac gacgatgctg cggcggatca acgtggcggc ggtgctggac
    16381 gcggtccggc ggtccgcccc ggcgccgctg cgggtcgcgg agctggtcga gcggaccggt
    16441 ctggccagac cgaccgtcgc gcaggccgtc gacgagctgc tggacaacgg ctggttgcag
    16501 cagcacggtc ccgactccgc cgaccgctcg ctgggccggc cggccatccg ggtctcgctg
    16561 cgcggccgcg cggcgccggt gctcgggctg gacgtcggcc cgcaccgggt gaccgtcggt
    16621 gtctccgacc tggccggtcg caagctgtcc ctcgtccgcc ggtccggccc gggctggacc
    16681 gcccaggagc tgctcggcgt gatcagcgag gtgatcaccg aggcgctgga cgaggcggag
    16741 gtcccggccg aggacatcgc cgcggcggtc gccgccagcc cgggcatcgt cgacgagcac
    16801 accggccggg tccagctggc cccgagcgtg ccgggctggt cctcggtcga cctggtcaag
    16861 cacgtacgca gcctgctcga ctgcccggtg atgctcgaca acgacgccaa cctggctgcc
    16921 ctggcgatcg ccgccgcccg gggcgggacc ggcacgctgc tggccgtcca gtggggtgag
    16981 cggctcggtg ccggcatcgt gatcgacggc cggctgcacc gcggcaccgg cgccgccggc
    17041 gagatcggct tcatcgcgac cgcgacggac gacgtgatca atcccgagga cagtcgcgga
    17101 ccgttggagc gtgccgtcgg ttccgaggcg atcgccgcgc tcggccggca ggccgtgctc
    17161 gaccacccgg actcccggct cgccgagctc ggccgcgacc agctggacac ggccgacgtg
    17221 ttcgccgcgg ccgccgagcg tgatccggtg gctcaggccg tcgtgcagca ggtcgcccgc
    17281 gacttcgccc gcgcgctggc ccccgctgtc ctggtgctcg acccgacggc cgtggtgatc
    17341 ggtggcggcg tcgcccgcgc cggcgccgta ctgctcgacg ccatctccga ccagctgcgg
    17401 ctgctcacgc tcaaccaccc gaagctggaa ctgtccgcgc tcgccgagga cgctgtcgtc
    17461 accggcgcga tgcggatggc gctggacgag gtgtggcagc gcaagctccc gactccggcg
    17521 ctgaccacca ccgcataatt tctgcagcgg tttgctcgtc ctgaccggcg ggcaccgcgc
    17581 acccatgagc acctggaccg agagccgccc ggttcgcagc gccggcgtac tggttctgct
    17641 ggtcgccgcg gtcgccgccg cggcgctgat cggcgtcctc ggggtggacg gcaccgccga
    17701 gcgctaccag cagctgcagc agccgtcctg ggcgccgccg agctggctgt tcggcccggt
    17761 gtggacagtc ctgtacgcca tgatcgccgt cagcggctgg ctcgtctggc gccgcgtcgg
    17821 ctggagccgc gcactcgtcc cgtacgccgt ccaactgctc ctcaacgccg cctggactcc
    17881 gctgttcttc ggcgccggag cgatcggacc ggccctggtg gagatcgtgc tgctctgggc
    17941 caccatcgcg tggaccgtgc tcaccttcgc ccgggtccgc cggtccgccg cggccctgct
    18001 ggttccgtac tgggcctgga ccaccttcgc caccgcgctg aacgcctcga tctggtggct
    18061 caaccgctga gctgaccact cggcacacgg ctgtgacact gcagtgggat gatcactgcg
    18121 tgtcagggca acaggccatc ccgaagtggc agcagtcggc agccggctgg gtaggtctgg
    18181 cggtcgtcag cgcggccatc tggtcgttcg tcgcggtccc gctgcacctg gtcgctcccg
    18241 aggtggtgaa gcgggtcgag ggagtcatcg acttcaccgg catcccggcc gggcacacgt
    18301 ttctctccgc ggtctacctg gctgtcgtcg gcagcgcgct gctgcgcggc aaacgagctg
    18361 ccctgctctg ggtgctgtgg gttttcgagg gcctgacgct ggtcacccag atcgccgcgc
    18421 tcggcttcat cagcgtgcgg atcgcgaacc cgaacgaccc cgacctgatc gccgagttcg
    18481 gccgcgcctc gatcgaggac ctggaggtcg gcatcgtccg ggtgctcgtg ccggcgctgc
    18541 tgatcgtgct gctgtggcgg atccgggaca gcttccccgc ccggctcgcc ccgggcagcc
    18601 ggcgggtggc gatcggcgta ctggtcaccg gcctgctgat ctcgatcgcg gtcagcatcg
    18661 cgctgaccca ggtcgtcccg aacacgctgc agggccagaa ggagaagatc ggctgggcgg
    18721 tgttctccgc cttcggccag agccgggcgc ggatgggttc cgggcacgag gggcatgcct
    18781 gggtcgggct gaccgtcggc ttcctgtccg ccgcttcgct ggtgatcgcg ttctggatct
    18841 tcctgcgctc ggtccgccgg gtccgctacc tcagccaggc cgaggagctg caggtccgtc
    18901 gcctgctgct ccagtacggc gaacgcgaca gcctcggcta cttcgccacc cggcgcgaca
    18961 aggccgtcgt cttcgcgccc ggcaacgacg ccgcgatcgc gtaccgggtg gtgaacgggg
    19021 tcagcctggc cagcggcgac ccgctcggcg acccggcggc ttggcccggc gcgatcgagc
    19081 agtggctcgc cgaggcccgc atctacggct ggtccccggc cgttctgtcg gccagcgagg
    19141 aggccgcccg cgcgtacgtc gacgccgggc tgcgggcgct cgcgatgggg gacgaggcga
    19201 tcatcgacgt cgccgacttc agcctcgagg gccggacgat gcggccggtc cggcaggccg
    19261 tcacccgggt ccagcgagcc ggctaccacg ctcaggtcgt ccggcacggc gacctcgcgc
    19321 cggacgacct cgcgcagtac gtcgagctgg cggagcggtg gcgcggggcg cggaccgagc
    19381 gcgggttctc gatggcgctc ggccggctcg gggacgccgc cgacgcgcgc tgcgtgatgg
    19441 tgatcgcgcg ggacgccggc ggcgccgtgc gcggcctgct ctcgttcgtg ccgtggggcg
    19501 tgcgcggtgt ctcgctggac ctgatgcgcc gcgacccgga gtcggtgaac gggttgatgg
    19561 agttcatggt caccgcgctg gtggacgcct gcggcgatct cggcgtgcac cggatctcgc
    19621 tgaacttcgc gatgttccgg gagatcttca gcgacgccga gcgggtcggc gccgggccgg
    19681 tgctgcggct gacgaacgcg ctgctcaccg cggcctcgcg gttctggcag ctggagagcc
    19741 tctaccagtc gaacgagaag tacctgcccc gctggtcccc gcggctgatc tgctactcgc
    19801 ggggcgcttc gctcgcgcag gtgctgctcg cggccgggac cgccgagggg ttcctgccgg
    19861 cgccgcggcc gtggacccgg gtcgacgccc gcagtaccgc ggaccgcaac gccatcgcgg
    19921 tcggcgacga cggccggttc gcgatcaccg tgcaggagca ggaggacgag ctgctccggc
    19981 ccgcgctgcc ggaccgccgg ctcaccgagc aggaacgcat ccggcgggcc aagtcgtccg
    20041 cgatggttgc tgagggcatc gatccgtacc cggtctcggt gccgaggacc gaaaccctgg
    20101 agcggatcct cgcgctgcac cagaacctgc cgcccgacca ccacaccggt caccacgtct
    20161 cggtcaccgg gcgggtgatg cggctgcgcg accacggcaa cctggcgttc gcccagctgc
    20221 aggacggcct cgaccagctg caggtgatgc tcgcggccgg cacctgcccg gccgaggacc
    20281 tgcggaactg ggaccggttc gtggacatcg gcgaccacgt cagcgtcacc ggcgaggtgg
    20341 tgacgagtcg ccggggcgag ctgtcggtcg cggtgaccgg ctggacgatg gcggccaagt
    20401 gcctgcaccc gttgccggac aaacgcaagg gtttcaccga tcccgaggcc cgggtccggc
    20461 agcgccacct cgacctggtg acgaacccgg acgcgctgcg gatgctgcgg caccgcagca
    20521 ccgcggtacg ggccctgcgg cacgggttcg aggcgcgcgg attcgtcgag gtggagacgc
    20581 cgatgctgca ggcggtgcac ggcggggcga acgcgcggcc gttcgtcacc cacatcaacg
    20641 cctacgacac cgacctgttc ctgcggatcg cgccggagct gttcctcaag cggctcggcg
    20701 tcggcggact cggcaaggtc ttcgagctga accgcaactt ccgcaacgag ggcgccgacg
    20761 ccacccacaa ccccgagttc acctcggtcg aggcgtacca gccgtacgcc gactaccacg
    20821 tgatgcgcga gctgacccgg gagctgctgc tggagacggc cgtcgcggtg ttcggcaaag
    20881 cggtggtcca gcgcgacggt gcggagctcg acatctccgg cgactggccg gtcgtcaccg
    20941 tgcacgacgc ggtcagccgc gccgccgggg tcacgatcga ccccggtacg ccggtcagcc
    21001 ggctgcggga gatctgcgcg cagcacggcg tccgggccgg cttcgacctg tcggccggcg
    21061 agctcgtcct cgagctgtac gacgagctgg tggagccgcg gaccacgcta ccgacgttct
    21121 acaccgactt cccgctggag acgtcgccgc tgccccgggg ccaccgcacc gatccgcggc
    21181 tggccgaacg ctgggacctg gtcgccttcg gcgcggagat cggtacggcg tactcggagc
    21241 tggtggaccc ggtcgagcag cgccggcggt tgaccgagca gtcgctgaag gcggccgcgg
    21301 gcgacccgga ggcgatgtcg ctggacgagg acttcctggc cgcgctggag tacgcgctgc
    21361 cgccgaccgg tgggctcggg ctgggcgtcg accggatcct gatgatgctg accggccaga
    21421 acatccgggc cacgctggcc ttcccgttcg tccgtcccac cccccggagc tgagctcgcg
    21481 ccgcagcccg tgcacgtccg ggtcgcgggt gcaccggacg agccttacgc tttgccgaca
    21541 aggattttcc atcctggggg gcagcgatgc ggaagatggt ctcggtggcg ctgggggtgg
    21601 cgctgctcgg tctggcgacc ggctgtggga acggcgacga cgccgcggac gacgcgccga
    21661 cgagctcggc gacgacgacg tcggtcccga cagcgagcgc gccggccagc gcgcccagtg
    21721 cgccggcgtc cacaccggcg gggccggtga ccggagcgca gtaccaggca cagctggccg
    21781 aggcggaccg acgcatcgcc gccgaggtac gcggcctcac cggcgccaac tccgcgacca
    21841 atctgcagaa cgcgatcctg agcctgtcgg agcgactgac gaccgaagcg acaatgctgg
    21901 gcgccctcca ggttcagccg cacgtcgccg ctgcgcacaa aacgctgcag acccggcttc
    21961 gcgcggcagc cacggcgttg tcggcgcacg acacggtcgg gaccgacgcc aagtgcggcg
    22021 gcgtcgtcta cacctcccag accgtgcagc ggaagctgac cgcggacctg accgcggcgg
    22081 tcaccccgtt ggccaagctc gggctgaggt tcggcacctc gctgccgaag gtcgagccgg
    22141 agcccgccga ccagcgcccg tcgaacggcg acgtcctggt ccgttcgggt ccgcgcggct
    22201 cgggccggct gcaggtgaag aacgggaccg cccaggacgt cgcggtggcc gtggtcaccg
    22261 acggcaagcc gccggccaag ccgcacctgc tggtctacgt gcaggcgaag aagaccgcga
    22321 cgatcagccg gatcggcggc cagtaccacc tctacgccaa gagcggcacc gactggaacc
    22381 cgaagcgccg gcagttcagc aaggactgca gcttcctgaa gttcgaccag ggcttcggcc
    22441 gcaacgaggg ctggcgggtc gacctgcaac cgtccgccct cggcaacgcc tccaccagcg
    22501 acgtcgcccc gttctgaccg cgagcgcggc ggctagaaat cgtccggcag caagcggtac
    22561 gccgcgtgtg gcgtcagcgg ccggaccgca cggaagtccc gccggtcgag cgtcaggagg
    22621 gtgtcggtcc ggtactccgc cgccagggcg accgtgacgg cgtccgcgag atccaggtcc
    22681 agatcggcgt agcggcgcat cacggccgtg gcggtttgca ggatcggcgt gctgatttcc
    22741 ggcacctgaa agcgcatcct ctgcacctgg gcgaagagca ggtcgagaat cgccgtccgt
    22801 gccgccgcac cgagacgtgc cctggcaagg tggtcgacct ccgccagaac cagcggagac
    22861 aggatcaccg tgccggcgtc ttgcagcgcc tg
//
