LOCUS       NC_013729              24961 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Kribbella flavida DSM 17836, complete sequence.
ACCESSION   NC_013729
VERSION     NC_013729.1
KEYWORDS    RefSeq.
SOURCE      Kribbella flavida DSM 17836
  ORGANISM  Kribbella flavida DSM 17836
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 7579488)
  AUTHORS   Pukall,R., Lapidus,A., Glavina Del Rio,T., Copeland,A., Tice,H.,
            Cheng,J.F., Lucas,S., Chen,F., Nolan,M., Labutti,K., Pati,A.,
            Ivanova,N., Mavromatis,K., Mikhailova,N., Pitluck,S., Bruce,D.,
            Goodwin,L., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D., Chen,A.,
            Palaniappan,K., Chain,P., Rohde,M., Goker,M., Bristow,J.,
            Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C., Klenk,H.P.
            and Brettin,T.
  TITLE     Complete genome sequence of Kribbella flavida type strain (IFO
            14399)
  JOURNAL   Stand Genomic Sci 2 (2), 186-193 (2010)
   PUBMED   21304701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Kribbella flavida DSM 17836
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024345.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,131
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 7,033
            CDSs (with protein)               :: 7,033
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 8 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 4 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name             :: Kribbella flavida DSM 17836
            Culture Collection ID :: DSM 17836, JCM 10339, KCTC 9580, NBRC 14399
            GOLD Stamp ID                     :: Gi02235
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: GeneMark
            Isolation Site                    :: Soil from China
            Isolation Country                 :: China
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:11:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4552957
            Orig. end                         :: 4577918
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001736.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082793
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24961
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24961
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24961
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14961](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14961)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            801..1283
                     /locus_tag="KFLA_RS21025"
                     /old_locus_tag="Kfla_4238"
     CDS             801..1283
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KFLA_RS21025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Kfla_4238"
                     /product="hypothetical protein"
                     /protein_id="WP_041289421.1"
                     /transl_table=11
                     /translation="MRRGRVAVAGRVRTMAVLEVVNVAVIGWFVFGALDAPVSAANAAG
                     FLASAGLLLVGAAYWMAKLGQVRSALRRPRHLEAFRLVRIACLVGLLAAGVVVAAAVGD
                     PARRFVPGLTLFLLAVAEYVNYFHWQLMYDNRADLQRLFRTRRLARAHLHRDLHPG"
     gene            complement(1284..2117)
                     /locus_tag="KFLA_RS21030"
                     /old_locus_tag="Kfla_4239"
     CDS             complement(1284..2117)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084228.1"
                     /locus_tag="KFLA_RS21030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4239"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_237706550.1"
                     /transl_table=11
                     /translation="MSTSIGFFTRLTITCKNADEQGGMWMLAAQRRDLLLERLVADGRV
                     VAKDLATELGISEDSIRRDLRELAAAGLCQRVYGGALPISPAVADYSTRETVAVDSKTV
                     VAGLAASLVRPGSAVILDGGTTARAVVAALPLTLEATVITHSPTIAAALVEHRGIEIFL
                     IGGRVFRHSMVASGAAAVEAAQAVSADLFLLGVTGVHPEAGLTTGDADEAAMKRALSRR
                     AAETYVLASAEKLGTASRFSVLPLHEVAGVVTDAPAGHRTVRELHGAGVPVIGPS"
     misc_feature    complement(2037..2039)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            2092..2466
                     /locus_tag="KFLA_RS21035"
                     /old_locus_tag="Kfla_4240"
     CDS             2092..2466
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KFLA_RS21035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Kfla_4240"
                     /product="DUF4406 domain-containing protein"
                     /protein_id="WP_237706551.1"
                     /transl_table=11
                     /translation="MKKPMLVLIAGPYRSGTDGDPDRIAANLRRLEGAAWPIHAKGHIP
                     MIGEWVALPVLRGAPQVESPDGPEGDVMYDVAGRLLQHCDAVLRLPGESHGADRDVEIA
                     ETRGLPIYRDAADIPAFVPQ"
     gene            complement(2984..6397)
                     /locus_tag="KFLA_RS39395"
                     /old_locus_tag="Kfla_4241"
     CDS             complement(2984..6397)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="KFLA_RS39395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4241"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_158307293.1"
                     /transl_table=11
                     /translation="MTTPRMIGRERETRLLRTAVTAAPSLVLVVGEAGTGKSRLVAEVA
                     RDHPARWLTGQCHPVQDETPLTPVLEALAPVSDQQPGAGTPWRGALVPGMRHSVFARTR
                     ELLASLGPTVLVVEDLHWADPGTLQLLRFLASRLPREVRVVATYRPEDTLVAGEITALA
                     GCVPPGTRTTEVRLHPLAPHAVREFAAQMLGVDELPDGLARELFERTGGLPFVLEEFLR
                     DVAIGADGSLAPVARALAETRAPVALRAAVAIKLEQLPEACRRVVWATAVLDAPSPDAL
                     IGAVAEVGAAELADAVDAALARALLGESRPGLYDLRHALGQRAVYETIPADELRRLHRR
                     AAEAVGSRDPGAHARIAAHARRGGLVGTWLTEAELAAAQLVECGKADRAVEQLLEMLRF
                     EGLAWADRARLATRLGHAAVESAQWDEAVVAMRMVLDELVVASGDRGSLRLALGLVLHD
                     RAGEFAAARRELAAAVEELGGDPIAAALAMSTLAVPTSGAEEIAEHRAWMHRALRLLGE
                     PTQSAWPAAAGASPLAVRRSGASARRDGVGYADVREGGRSGIAGVRDGSTDDAASGRTR
                     VVGGSVAGDVVRPRDGAGESAGVGIEGPPGVTGVRGGGAPGASGGRSGGAVGTSSARRA
                     GEAGGVAGVADARRSRRVDAVAGGGVRRDAAAGDAGRRQIASVGGVDVPVAGSAGDGDV
                     RGSRSAGDGDVRSKGLAGGGSGRDGGAAVRGVWRNRGRLLLAAGDLAGDDGTADAARGL
                     LWLGHDRRSRELPAGVGTRLWQAWLAGQWEELPERLLRARSETASAPLVRAEVELVTGR
                     LHLVRGDLSAAMEVLESVRGELPVRAAALATIGRMQLALGQTDAAVEAVEDFVSVVRRK
                     DGWAWAGELVATTCVAWDRSERRPDALGLLQEFDAGLVGRDAPASVAASKLARAFLSIG
                     DTADRERTAHRGDREPGGECGGGRGEGRGSGQAGSGNASRASTGLHPSTTSPRPTSPSG
                     AGEAAVRPSADWFEMAAAAYRAIGRPYDECCALEGRARRALELGDAQELVALEARYEKL
                     GARWDARRCREALREAGVAVTSRRGRRGYGNALSPREHEVARLAARGLSNNRIAAELSL
                     SVSTVEDHLSRAMRKLKIRSRRDLGPLIAP"
     misc_feature    6515..6528
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.53"
                     /tool="antismash"
     gene            complement(6893..8083)
                     /locus_tag="KFLA_RS21045"
                     /old_locus_tag="Kfla_4242"
     CDS             complement(6893..8083)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391260.1"
                     /locus_tag="KFLA_RS21045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4242"
                     /product="hypothetical protein"
                     /protein_id="WP_237706552.1"
                     /transl_table=11
                     /translation="MSLSRLRRVELPSGRVTELGKLDYLVDAMGYARSQDLVYGIASRD
                     RHGWLHRRPHLVTINRQGLVRDLGEVRRGVGGVAAPTAGAVAGHRLYLRDGLRLFTMDI
                     DPDSTTYKSVLRVVRLKPVLGALTVDDLAADPVSGFLYGISTVGAGPAKVVSVDPGSGT
                     VRAVADVRGVPSTASYTSVVLSGRALYAVHTRPGSRSRAVRIALSGEVREVTSWEPVWT
                     GDAAGCLQQVPTPPPPPPTPTPRPPTASPPPSPTQTPRPPSPPPTVRPPSPPPPGVRPP
                     SPRPPNARPPSSTPPNRRPVSPGPSPRPTATTPLPTPTEAAELPVRPTPSPTPRPTSRP
                     LPPLVTPPVVSVAPRMAAVPEEPDDTVLVLRRWSLATLLMILTGAAAMAAQRRMRR"
     gene            complement(8220..8987)
                     /locus_tag="KFLA_RS21050"
                     /old_locus_tag="Kfla_4243"
     CDS             complement(8220..8987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391259.1"
                     /locus_tag="KFLA_RS21050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4243"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_012921833.1"
                     /transl_table=11
                     /translation="MSLFFSGLFWVLGLMMVTAVLAVILRKARQRFGREANNEVAGQVF
                     TIVGGVNVVIAAFVLISLFDATDKADENTYQEANALVAVRWASESLAEPARSRVEELTQ
                     SYANEVVQVEWPALRAGGPVGGQGWELLSELQGEVERVPTRTDREENSRIEASTQLWNV
                     YQARQDRLNASGNGVSAIVWFAILVGSAMSVGLMFMFGGPGVYSYAVIVSMLSGAIALM
                     LFAIYQLQDPFSGGASVGPDAYVAALTRLARSG"
     gene            complement(8984..9988)
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /locus_tag="KFLA_RS21055"
                     /old_locus_tag="Kfla_4244"
     CDS             complement(8984..9988)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /gene_synonym="lytB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391257.1"
                     /locus_tag="KFLA_RS21055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4244"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_012921834.1"
                     /transl_table=11
                     /translation="MTRRTILLASPRSFCAGVERAIEIVEQLLARRRSPVYVRKQIVHN
                     THVVADLESRGAVFVDELDEVPADATVVFSAHGVAPAVRAEAERRGLDVVDATCPLVTK
                     VHAEARRYAGRGDTVVLIGHAGHEEVEGTMGEAPDRTVLVETVDDVAALEVEDAGRVSY
                     LTQTTLAVDETAAVLDALRAKFGALRGPDSADICYATTNRQEALGALSDDADLVLVVGS
                     DNSSNSRRLVELARRRGTPAYLIDDGSGLRPEWLDGVRVIGLTAGASAPPRLVDGVVAA
                     LAAFGPVDVVEREITRETVHFTLPVAVRSGAVRDRGCVGPGEFRVQSGRGSQG"
     gene            complement(10001..11107)
                     /locus_tag="KFLA_RS21060"
                     /old_locus_tag="Kfla_4245"
     CDS             complement(10001..11107)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073756.1"
                     /locus_tag="KFLA_RS21060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4245"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_012921835.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.8e-58, bitscore:
                     195.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLERLDPADSPPSGTTDGTGATTSGDAMNRVLAQRALGWSRDQ
                     VEPALRAAVGKLPLATQRITNYHFGWEDEDGTPTRADGGKALRPALALLASQAVGGTTA
                     AAVPAAVAVELVHNFSLLHDDVMDCDTTRRHRATAWTVFGLGPAILAGDALLSLAFDVL
                     VSSGEPAADDGAKVLGQAVQELVEGQLADAHFEIRNDVTLSECLRMAQLKTGALLGCST
                     ALGAMFGGGRSEQVDHLRLFGEDLGLAYQYVDDLLGIWGDPRVTGKPVHSDLRRRKKSL
                     PVIAALTSGTAAGQELAALYQGSRDLTDAELVRAAGLIDEAGAKAQSQAQADALLTAAL
                     GELRSASGAVGAADDLERLARWATRRDR"
     gene            complement(11117..12520)
                     /locus_tag="KFLA_RS21065"
                     /old_locus_tag="Kfla_4246"
     CDS             complement(11117..12520)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391255.1"
                     /locus_tag="KFLA_RS21065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4246"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_012921836.1"
                     /transl_table=11
                     /translation="MTTSETETETQTRPQLSLGTAAARQLASTTKSVPQMQGISPRWLL
                     RILPWVETKGGAYRVNRRTSYAIGDGRLTFSATGADVRVIPQELTELPPLRELQDPEVL
                     QELANRFGQEEYEAGQVLTEFGSRIDDVLLIAHGKISKIGIGRYGDGTDLGTAADGDYL
                     GEQLFTDPPESIWEYTARTTTRCTVLRLTRQALEQLRDRSEVLREHLDELRSRPRPAQN
                     KNGEAEIALSSGHAGEADLPGTYVDYDPAPREYELSVAQTILRVHTRVADLYNHPMDQT
                     EQQLRLTIEALRERQEHEMVNNREFGLLHNADFKQCIYPRTGPPTPDDFDELLTRRRKP
                     RALLAHPRAIAAFGRECSKAGVYPESALVEGRRVQAWRGVPILPCNKIPIAADNTTSVI
                     VLRTGLEDEGVVGLRQTGLPDEIEPGLNARFMEINEKAVTSYLVSTYYSVAVLVPDALG
                     VLENVELGG"
     gene            complement(12517..14961)
                     /locus_tag="KFLA_RS21070"
                     /old_locus_tag="Kfla_4247"
     CDS             complement(12517..14961)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391254.1"
                     /locus_tag="KFLA_RS21070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4247"
                     /product="Terpene synthase metal-binding domain-containing
                     protein"
                     /protein_id="WP_012921837.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-84, bitscore: 283.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAPQPPGAAARLVSHVGRDATDEPGGLTKGGSPPTGRPTPSTGQ
                     STLRTGQPTSNARQPAPSRERAAPSGGQPYQLPEFYVPYPARINPHLEQAREHSRAWAY
                     AFDMIDVPQQGKAIWDLRDFDSHDYALLCAYTHPDAGAAALDLVTDWYVWVFYFDDHFL
                     ELYKKTQDTAGAKAYLNRLAAFMPVDGAITETPENPVERGLADLWARTVPSMSEGWRRR
                     FAATTESLLAESLWELSNISAGRLPNPIEYVEMRRKVGGAPWSANLVEYAVQAEVPEEV
                     AHARPLKVLSDTFSDAVHLRNDLFSYQREVEAEGELNNGVLVVERFLGCSPQRAADLVN
                     DILTSRLHQFENTALTEVPPLLAEHRISPQGRLDVLSYVKGLQDWQSGGHEWHLRSSRY
                     MNDGGQAATLGPSALLDGPKGLGTAASRILQSMVTSAPYRIRSYTHRLYDVVEPFERPE
                     LYMPYRAKLSPHLDRARANVLEWGQRMGLTDGVIWDARMLLANDLPLCAAGIHPDADPD
                     ALDLSSQWLAWGTYADDYYPVAFGRSRDLVGAKATNKRLSALMPLELDAAGPPVPGNAL
                     ERSLADLWSRTAGPMAPDARRAFKDAVETMIDSWLWELANQFQHRIPDPVDYLEMRRRT
                     FGSDLTMSLCRIGHGRTVPPEIYRTRPIRALESAAADYACLLNDVFSYRKEIQYEGELH
                     NGVLVVRNFLDCDLSTAFAVVNELMTARMRQFEQLVAVDLPVLFDDYELGDDVRRVLTG
                     YAEELQNWMSGILVWHAGCRRYDEGAQLHLPRKLLGGATGLGTSAESIGRSLAMKRLEG
                     AL"
     gene            complement(14971..16380)
                     /locus_tag="KFLA_RS21075"
                     /old_locus_tag="Kfla_4248"
     CDS             complement(14971..16380)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391253.1"
                     /locus_tag="KFLA_RS21075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4248"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_012921838.1"
                     /transl_table=11
                     /translation="MTQPASSDAQVQRPQLSLGTAAARNLATTTKSEPQMQGITSRWLL
                     KMLPWVQVNGGAYRVNRRLSYAVGDGRVTFTTTGAEVRVIPQELCELALLRSFDDVEVL
                     TELAGRFEQQEYQPGDVLVERGRPADRICLIAHGKVNKIGAGKYGDETVLSTLTDGDHF
                     AYQALLESEDHWQYTVKAITPCTVLSLSQDAFEDLVARSDSLRAHVEAFRANPAPAQDE
                     YGEAAIALASGHEQEAELPGTYVDYETTPREYELSVAQTVLRVHTRVADLYNHPMDQTE
                     QQLRLTIEALRERQEHEMVNNREFGLLHNADLSMRIPTRTGPPTPGDLDELLGMVWKEP
                     AFFLAHPRSIAAFGRECTKAGVYPDSVDLGGHRVPAWRGVPIFPCNKIGISETRTSSIM
                     LLRTGEDSQGVVGLHQTGLPDEYEPGLSVRFMNINEKAIINYLVSAYYSAAVLVPDALG
                     ILEDVEIGRES"
     gene            complement(16798..17685)
                     /locus_tag="KFLA_RS21080"
                     /old_locus_tag="Kfla_4249"
     CDS             complement(16798..17685)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391252.1"
                     /locus_tag="KFLA_RS21080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4249"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012921839.1"
                     /transl_table=11
                     /translation="MTKTIELSGVQQRFHARGAVGGYLTAVQDATFTLAPEPPQVVSLV
                     GQSGSGKSTIARNVLGLQKPTSGTVRYGGKDIFKLTRAEYDDYRRNVQPVFQDPYAIFN
                     PFYRVDRVLWKAVKKFGLASSRSEGLALIERSLEAVKLEPERVLGRYPHQLSGGQRQRV
                     MLARIHMLRPAFVIADEPVSMLDAQVRRLFLDILLDFQREYGMTTLFITHDLSTVYYLG
                     GSVMVINRGVIVERGPVDTVMHEPSHPYTRLLLDSIPQPDPDLRWTGRIEVDELSGTAE
                     AGTPKATAPETPII"
     gene            complement(17682..18500)
                     /locus_tag="KFLA_RS21085"
                     /old_locus_tag="Kfla_4250"
     CDS             complement(17682..18500)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391251.1"
                     /locus_tag="KFLA_RS21085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4250"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012921840.1"
                     /transl_table=11
                     /translation="MSDDEIVLEISGLEVGYSTNRGEVKAVRGLDLAVRRGEILGIAGE
                     SGSGKSTLAVALLRLLKPPGKVMAGSALFRPRGRSPVDLLKVSGEELRVLRWSALSYLP
                     QGSMSSLNPVMRIGDQFRDVILEHAPERKDTLSELIPRLLGQVGLEPAVARMYPHELSG
                     GMKQRVLMAICVALEPDLVIADEPTTALDVTIQRVILQSLVDLQRDFGVTLMVISHDMG
                     VHAQLADRVAVMYEGSLVEVGDVRQVYKQPRHEYTRQLIESIPLVGRRAS"
     gene            complement(18493..19368)
                     /locus_tag="KFLA_RS21090"
                     /old_locus_tag="Kfla_4251"
     CDS             complement(18493..19368)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391250.1"
                     /locus_tag="KFLA_RS21090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4251"
                     /product="ABC transporter permease"
                     /protein_id="WP_012921841.1"
                     /transl_table=11
                     /translation="MRLLTATVKTVRQSHRLAAGLVILTLMVLLAVLSPVLVDAIGKGT
                     DPIELAAYEKWLVPSADHLLGTDQYGRDVLAMVISALSVSLQIGAIAGVISTVVGVVVA
                     FVAGYKGGWVDGVLSTFTGILLVIPTFPLLIALSAYAKNVSLFQVGVMISIFSWPFAAK
                     TIRSQVLSLRSRPYVDLARVSKARDLEIIATELLPNLLPFIGVGFASSALGAIFGLVGL
                     EVIGLGPGGVIDLGQIIFNAINTGALTLGAWPMFVVPIVLLTLLFAALNMINIGLEEVY
                     NPRLRGVAGE"
     gene            complement(19374..20471)
                     /locus_tag="KFLA_RS21095"
                     /old_locus_tag="Kfla_4252"
     CDS             complement(19374..20471)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020574863.1"
                     /locus_tag="KFLA_RS21095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4252"
                     /product="ABC transporter permease"
                     /protein_id="WP_012921842.1"
                     /transl_table=11
                     /translation="MTATAPPAETVVGESAESAPSRGGRAWLARHPLAAYALRRFGLYL
                     VELWGALTIAFFFFRMIPGDPIQTLIQTLQQNYVYNQQASEEIIERYRHEFGLDGNIFS
                     QYLKYMENLILHGDLGPSLLNYPTPAQDVIMHSLPWTIGLLGVAAVMSWILGLVIGAIA
                     GWRRGKLGSTITTNLSIALAHVPFFFVALILVYVFAYTLGMLPARSAYDSAISPGISAD
                     FIGSVLKHALLPGFSIMLIGTFGWILSTRMLMVPVLGEDYLVYAEAKGLKPWRILTRYA
                     LRNCYLPQVTAFGISLGFIFNGNVLVEQLFNYPGLGTTLVTAIQQLDFNTIIGVTDIAI
                     FSVLTAVLLLDLLLPLLDPRVKYWK"
     gene            complement(20468..22303)
                     /locus_tag="KFLA_RS21100"
                     /old_locus_tag="Kfla_4253"
     CDS             complement(20468..22303)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391248.1"
                     /locus_tag="KFLA_RS21100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4253"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_012921843.1"
                     /transl_table=11
                     /translation="MNDAPRPQFEDVADVLRYQLSRRSLVGGGAAAGLAGLLAACSGSG
                     GSYSDKPANKPAATKSVQIGKANIPTPRDQTVVVGQVEYNVFDSFNTMIPNGWQSGAGF
                     ESVCREAMFYLNLATGELKPWLATGYKYNDSHTQLTFTFDPKAKWSDGKPLTANDFRFT
                     VMLLKDRKDLFGGGGDLGEFVQDVEVPDQHTAVIKMKKATPRLHYTFVAAIASGFDILP
                     EHVWKGQDPTKFKENPPTRTGPYKLKQAIRSQKMFVWEKNPDYWAKDQLDPAPQYVVYQ
                     STSKQADSASLAFERAEFDVGSIDEQHAKQLRNGGYPHLVTTQFHDPNPRVLWLNCDPA
                     RGVIAEPKMRWAINHCLDREKIGKSIWQVEVPAAIYPWADYPSNDKWKNDELAERYKFE
                     YNLDKANALLDEIAPKNAAGRRTYKGKEINLEIITPAPVNKDEYAIADVLKTDLAKVGV
                     PATLRSLTGSVHDEKFQRGEYDIDSNWAGFAFDPQQLYTDWESSKAQPIGKNAAGKNKM
                     RLRNPKLDELSLKLSQLDPTTPEAKPLLDEALELYFQQLPLLPVIQTGYPSFFNTAFWT
                     GWPTDDDLYQVPLNWWSHFIFVLGRLKATGQKGPA"
     misc_feature    22547..22560
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    22677..22691
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.77"
                     /tool="antismash"
     gene            22701..23516
                     /locus_tag="KFLA_RS21105"
                     /old_locus_tag="Kfla_4254"
     CDS             22701..23516
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (35-146). E-value: 1.6e-13. Score:
                     41.4. Matches aSDomain: nrpspksdomains_KFLA_RS21105_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020391247.1"
                     /locus_tag="KFLA_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_4254"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_012921844.1"
                     /sec_met_domain="PCMT (E-value: 8.1e-05, bitscore: 21.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTAVDFAAIKDKQRAGWQTGDYPRVGNTLQIIAELLVEAADVR
                     AGQRALDVACGQGNAAIAAARRFAEATGVDYAANLLAQGRERAAAEHLDVTFTEGDAEN
                     LPVPDASFDLVLSTVGVMFAPNHQQAADELIRVTAPGGKIALSSWTPTGMVGQMFKVVG
                     KWTPPPAGVKPAVLWGTEEHLTELFGDRVQWIALNKREYVFRYHSPEHFSEWFRQFYGP
                     ITKLAGSLSEQDRATFAAELADVPRSFNQADDGTVAARAEYLEAVGVRR"
     aSDomain        22806..23138
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KFLA_RS21105_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.60E-13"
                     /label="KFLA_RS21105_oMT.1"
                     /locus_tag="KFLA_RS21105"
                     /protein_end="146"
                     /protein_start="35"
                     /score="41.4"
                     /tool="antismash"
                     /translation="ELLVEAADVRAGQRALDVACGQGNAAIAAARRFAEATGVDYAANL
                     LAQGRERAAAEHLDVTFTEGDAENLPVPDASFDLVLSTVGVMFAPNHQQAADELIRVTA
                     PGGKIAL"
     gene            23595..23897
                     /locus_tag="KFLA_RS21110"
     CDS             23595..23897
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KFLA_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148256688.1"
                     /transl_table=11
                     /translation="MRFRGVRGVLTFASFASFASFASFAVCTACAAFAVGAACAVCAVC
                     AVCALAACAAFAPFTLFVPFAAFALFAPFPVCAARAVCAACAVCAVCARSRRRGG"
     misc_feature    23742..23744
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    24255..24270
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.23"
                     /tool="antismash"
     misc_feature    complement(24256..24269)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.29"
                     /tool="antismash"
ORIGIN
        1 gccggccgcg cgtccggatc agcggccgcg acgtcgccgg ggtggtcgag gcggtcggcg
       61 ccggcgtcac cgagctgaag gtcggcgacg aggtgtacgg aacgtgcgag agcggttcct
      121 tcgccgagta cgccgtcggc cgcgcggacc ggctgacccg caagccggcg aacctcacct
      181 tcgagcaggc ggccgccgtc ccgatctcgg ccgggaccgc gcttcaaggg ctgcgcgacg
      241 ttcgccccgg cgatcacgtc ctggtcctcg gcgcggccgg cggcgtcggc tcgtacgccg
      301 tccagctcgc caaggccgcc tgcgctcacg tcaccggcgt gtgcagtacg gccaagctcg
      361 acctggtccg cgagctcggc gccgacgaag cgctcgacta cacccgcgac gaactccccg
      421 ccgcggcgta cgacctgatc ctggacgccg gcgggaaccg ctctctgcga actcttcgcc
      481 gttctctgac gccgaaaggc accctcgtgc tcgtcggagc cgaaaccggt ggcgccctcg
      541 gcggcctcga ccgcgccctg cgcgcgacgc tgctctcccc cttcatcggc caacgcctcc
      601 gcggcctgat cagcaccgaa cgcgccgacg actacgccca cctgcgcacg ctcatcgagt
      661 tcggcaaggt gaccccggcg atcgaccgca cctatcccct ggccgaagcg cccgccgcca
      721 tccaccatct ccgcgagcgg cacccccgcg gcaaactcgt catcaccgtc tgaccggctg
      781 cagcggtgca caatggccgg atgcgtcggg gacgggtcgc ggtggccggc agggtgcgca
      841 ccatggcggt gctcgaagtc gtgaacgtgg cagtgatcgg ctggttcgtc ttcggggcgt
      901 tggacgctcc agtgagcgcg gccaacgccg ccggctttct ggcctcggcg gggctgctgc
      961 tggttggcgc ggcgtactgg atggcgaagc tcggccaggt tcgttccgcg ctgcgacggc
     1021 ctcggcacct ggaggccttc cggctcgtac gaatcgcctg cctggtcggg ctactggccg
     1081 ccggcgtcgt cgtcgcggcc gcagtcggcg atccggcgcg gcggttcgtc ccggggctga
     1141 ccctgttcct gctcgcggtg gcggagtacg tgaactactt ccactggcag ctcatgtacg
     1201 acaaccgcgc cgacctccaa agactgttcc gcacccgccg cctggcgcgg gctcacctgc
     1261 accgcgatct ccacccgggc tgatcaggac ggaccgatca ccggtacgcc ggcgccgtgg
     1321 agctcacgga cggtgcggtg gccggccggc gcgtcggtga caactccggc gacctcatgc
     1381 agaggaagta cggaaaaacg tgaagccgtg ccgagtttct ccgcgctcgc cagcacgtag
     1441 gtctcggccg cccggcggga cagcgcacgc ttcatcgccg cctcgtcggc gtcgccggtg
     1501 gtgagtccgg cctccggatg caccccggta acgcccagca ggaacaagtc ggcactcacc
     1561 gcctgcgccg cctcgactgc cgccgcaccg ctggccacca tcgagtgccg gaacacccgg
     1621 ccgccgatca ggaagatctc gatcccccgg tgctcgacca gcgccgccgc gatggtcggg
     1681 ctgtgcgtga tcacggtcgc ctcgagcgtc agcggcaacg cggccaccac ggcacgggcc
     1741 gtcgtcccgc cgtccaggat caccgcgctg cccggccgca ccaagctcgc cgcgagccct
     1801 gcgaccaccg tcttgctgtc gactgccacg gtttcccggg ttgagtagtc agccacggcc
     1861 ggcgagatcg gcagagcgcc cccgtacacc cgctggcaca gcccggccgc cgcgagctcg
     1921 cgcagatctc ggcggatgct gtcctcggag atgccgagct cggtcgccag gtccttcgcg
     1981 acgacccgcc cgtcggccac gagccgttcg agcagcaggt ctcgacgctg tgccgctaac
     2041 atccacattc ctccttgttc gtccgcattc ttgcacgtta tggtcaatcg cgtgaagaag
     2101 ccgatgctcg tactcatcgc cggtccctac cgctccggca ccgacggcga tcccgaccgg
     2161 atcgccgcca acctccgccg actggaaggc gccgcctggc cgatccacgc caaagggcac
     2221 atcccgatga tcggcgagtg ggtggccctg cccgttctcc gcggcgcccc gcaggtcgaa
     2281 tcgccggacg gccctgaagg cgacgtgatg tacgacgtgg cgggccgcct gctccagcac
     2341 tgcgacgccg tactgcgtct ccccggcgag tcccacggcg ccgaccgtga cgtagagatc
     2401 gcggagacgc gcggtctccc gatctaccgc gacgcagccg atatcccggc gttcgttccg
     2461 cagtaggaga ctcaccgccg actgcgcctg tcggcaccca gcacagcggc ccgcgcggga
     2521 gccgcgagag ttcgtcgatg gccgccgccg ggccgcccaa cgacgcgccg cgctggcggt
     2581 gaccgccgaa cagcgggcga gtactgctgc tcgaaggaca agttgaggac ggcgccgact
     2641 ggcagcgccg acgtcgccga cgggggcgcg gccgtcatgt cagggaggcc gtacgggggg
     2701 ccacctcgga ggtggccagg gcgacgcgga ggtggcccgg ggcgacgcgg tgtgcgccgc
     2761 agcgggctcg gcggaggcag agtccgccac agcgggcccg acgaacgcag agtccgccgc
     2821 tgcaggccca gggaaagcag agtccagcgg caggctcgag cgtacgcagc gtccaccgcg
     2881 gcaggctcga gcgtacgcag cgtccaccgc ggcaggcccc ggcgggcgcg gagtccaccg
     2941 ccgcaggccg ggcggacgca gtgtccggca gtgcgtccgc ccgtcaggga gcgatcagcg
     3001 gcccaagatc gcggcgggaa cggatcttca gcttccgcat cgcccgggag agatggtcct
     3061 ccaccgtgct caccgacagg gacaactcag cggcgatccg gttgttgctc aacccacgag
     3121 ccgcgagcct ggcgacttcg tgttctcgcg gagagagcgc gttcccgtat ccccggcgtc
     3181 cccgccgcga cgtcaccgcg actccggcct ctcgcaacgc ctcccggcac cgccgagcat
     3241 cccaccgggc gcccagcttc tcgtaccgcg cctccaacgc aaccaactcc tgcgcatccc
     3301 cgagttccaa cgcccgccga gccctgccct ccaacgcaca acactcgtcg tacggtcgcc
     3361 cgatcgcccg ataggccgcc gcagccatct cgaaccagtc agccgacggt cgaactgccg
     3421 cctccccggc ccccgaaggc gacgtcggac ggggcgaggt cgtcgagggg tgcaacccgg
     3481 tcgacgcccg tgatgcgttc cccgagccgg cttggccgct cccccggcct tcgcctcgcc
     3541 cgccaccaca ctcgccgcct ggttcacggt ctccccggtg tgcggttcgt tcccgatcgg
     3601 cagtgtcgcc aatgctcaga aacgcacgcg cgagcttgct cgcggcaacc gaagcaggcg
     3661 catcccgtcc aaccaagccc gcgtcgaact cctgcaacaa gcccaacgcg tccggtcgtc
     3721 gctcactgcg atcccaagcg acacacgtcg tagcaaccaa ctcccccgcc cacgcccacc
     3781 cgtccttacg ccgtaccacc gagacgaagt cctccaccgc ctccacggcc gcatccgtct
     3841 gccccagcgc cagctgcatc cgcccgatcg tcgccagtgc cgccgcccgt accggcaact
     3901 cgccacgcac cgactccagc acctccatcg ccgccgaaag gtccccccgc accaagtgaa
     3961 gtcgcccggt caccagctca acctcagccc gcacaagcgg agccgaagca gtctcactcc
     4021 ttgccctcag caaccgttcc ggcaactcct cccactgccc cgccaaccac gcctgccaca
     4081 accgggtccc aacccccgcc ggcaactccc ggctccgccg atcgtgcccc agccacaaca
     4141 acccccgcgc cgcatccgcc gtcccgtcgt cccccgccag atcacccgcc gccagcaaca
     4201 accgcccccg attccgccaa actccccgaa cagccgcacc cccatcacgc cctgaaccac
     4261 cacccgccaa gcccttcgac cgcacatcgc cgtcacccgc ggacctgctc cctcgcacat
     4321 cgccgtcacc cgcggagccg gccaccggca catcaacgcc gcccactgag gcgatctgcc
     4381 gcctacctgc gtcacccgca gcagcatccc gccgcacgcc gccgcctgcg acagcgtcga
     4441 cccggcggga tctccgagca tccgcaacgc ccgcaacccc acccgcctcc ccggcccgcc
     4501 gcgcactcga agtacccacc gccccacccg accgcccacc ggaagccccc ggcgcgccgc
     4561 cgccacgcac ccccgtgaca ccgggcggcc cctctatccc caccccagct gactccccag
     4621 caccatcccg cggccgaacc acatcaccag caacgctgcc tcccaccacg cgagtcctcc
     4681 ccgacgcggc atcgtcggtc gagccatccc gcacaccggc aatcccactg cgcccgcctt
     4741 cccgtacgtc ggcgtacccg accccgtctc gacgcgccga agcaccagag cgccgtacgg
     4801 cgagcggact ggcaccagcc gcggcaggcc acgcgctctg agtcggctcg ccaagcaacc
     4861 ggagagcccg gtgcatccac gctctgtgct cggcaatctc ctccgcgccc gacgtcggaa
     4921 ccgccaacgt cgacatcgcc aacgcagccg cgatcggatc cccgcccaac tcctcgaccg
     4981 ccgccgccag ctcccgtcgc gcggcggcga actccccagc ccggtcgtgc agcaccaggc
     5041 ccaacgccaa ccgcaggctg ccccgatcac cgctcgccac caccaactcg tccagcacca
     5101 tccgcatcgc gaccacggcc tcgtcccact gcgccgattc caccgccgcg tgccccagcc
     5161 gcgtcgccag ccgcgcccga tccgcccacg ccaacccttc gaaccgcagc atctccagca
     5221 gttgctcgac cgcccggtcc gccttcccgc actcgacgag ttgagcggca gccaactccg
     5281 cctcggtcag ccaagtgccg accaagccgc cccgccgagc gtgcgccgcg atccgcgcgt
     5341 gcgcgccggg atcgcgcgat cccacggcct cggccgctcg ccgatgcaac cggcgcagtt
     5401 cgtccgccgg gatcgtctcg tacaccgcgc gctgccccag cgcatgccgc aagtcgtaca
     5461 accccggccg cgactccccc agcaacgccc gcgccaacgc cgcatccacg gcatcggcca
     5521 actccgctgc accaacctcc gcgacagcgc cgatcagcgc atcgggcgag ggtgcgtcga
     5581 gcaccgcagt ggcccagacc acccgtctgc atgcctctgg caactgttcc agcttgatcg
     5641 cgaccgccgc tcgcaacgcc accggcgcgc gggtttccgc cagcgcccgg gcgaccggtg
     5701 ccagcgatcc gtcagccccg atcgccacgt cccgcaagaa ctcctccagc acgaacggca
     5761 gaccgcccgt ccgctcgaac aactccctcg ccaatccatc cggcagctcg tcgacaccga
     5821 gcatctgcgc agcgaactcc cgtaccgcgt gcggcgcgag cgggtggagc cgtacttcgg
     5881 tcgtccgagt ccccggcggg acgcagccgg ccaatgccgt gatctcgccg gcgaccaggg
     5941 tgtcctcggg ccggtaggtg gcgaccacgc ggacctcccg cggcaaccgg ctcgccagga
     6001 accgcagcag ttgcagcgtc cccggatccg cccagtgcag atcctcgacg accagcaccg
     6061 tcggcccgag cgaggccagc aactccctcg tccgcgcgaa cactgagtgc cgcatccccg
     6121 gaaccagcgc cccgcgccac ggcgtaccgg ctcctggttg ctggtccgag accggagcca
     6181 acgcctccag caccggcgtc agtggcgtct cgtcctgcac cggatggcat tgacccgtca
     6241 gccatcgcgc tggatggtcc cgagccacct cggcgaccag cctgctcttg cctgttcccg
     6301 cctctcccac caccagcacc agactcggcg ccgctgtcac cgcggtcctg agcaaccgcg
     6361 tttcgcgctc tctgccgatc atccgcggcg tcgtcaaccg accgcccgct cccccgctcg
     6421 tctttcgcac cgcagcctgc ctagtacgtc ccgactgggc ggcggcgagc ccacccccac
     6481 ctgacgacgc cagcccaatg gctgtccgtc ttcttcgaat tactctcagt cagcaacttc
     6541 acgcacatag tgtgaccgct cccctcgtcc ttcgacctgc cgaccccaag caaggtgagc
     6601 cgcactcacc ccgccgtcct ggcgctgacg gcagtggagg cggcggcata gttcgactgg
     6661 accgccctag gctcgaccgt gcgggcatag acccgacgag cgtcgcctcc cagagcatca
     6721 gcccgacctt gcggcatctt gatgcgcagg tgcggcgccc cactcggcca ccgacagcga
     6781 ggtcgcgggt ggcccggctg tccgactggg catgccggcg cgcggatgat cggccagagg
     6841 ggccggttct ggacgccaac cgaggccacc ctcgactgac ccgcacggca gttcatcggc
     6901 gcatccggcg ttgggcggcc atcgcggcgg cgccggtcag gatcatcagc agggtcgcga
     6961 gcgaccaccg tcgcagaacg agcacagtgt cgtccggctc ctcaggaacc gccgccatcc
     7021 gcggcgccac gctgaccacc ggcggggtca cgagcggcgg aagcggccga ctcgtcgggc
     7081 gaggggtggg cgacggagtc ggacggaccg gcaactcagc agcctccgtc ggcgtcggca
     7141 ggggcgtggt tgcggtcggg cgcgggctcg gccccggaga caccggccga cgattcggcg
     7201 gcgtcgagct aggcggacga gcattaggcg gacgtggact gggcggacgt acaccaggcg
     7261 gcggggggct cggaggacgg actgtcggcg gaggcgacgg cggcctcggc gtctgcgtcg
     7321 gcgaaggcgg cggcgacgca gtcggcggcc gcggtgtcgg cgtcggtgga ggtggcggcg
     7381 gagtgggcac ttgctgcagg caaccagctg catccccggt ccacaccggt tcccacgacg
     7441 tcacctcccg cacttctcca gagagcgcga tccgaacggc ccggctccga gagcccggac
     7501 gggtgtgaac ggcatagagc gctctcccgg acagcaccac cgaggtgtac gacgccgtcg
     7561 acggcacccc gcgcacatcg gcgacagcac ggactgtccc gctgcccggg tcgacgctga
     7621 ccaccttggc cggccccgca ccgactgtgg agatcccgta caggaacccg ctcaccggat
     7681 ccgccgccag gtcgtccacg gtcaacgccc cgagcaccgg cttcagccga accacccgca
     7741 gcacactctt gtacgtcgta ctgtccgggt cgatgtccat cgtgaagagc cggagtccgt
     7801 cgcgcaggta gagccgatgt ccagccaccg cgccggccgt cggagcggcg accccgccga
     7861 cgccacggcg tacctcgccc aggtccctga cgaggccctg gcggttgatc gtcaccagat
     7921 gcgggcgccg gtgcagccag ccgtgccggt cccgcgaggc gatgccgtag acgagatcct
     7981 gcgatcgcgc gtaccccatg gcgtcgacca ggtagtccag cttgcccagt tccgtgaccc
     8041 ggcccgacgg cagctcgacc cgccgcaatc gcgacaacga cacgggccca ctcgaatcca
     8101 cctgcagcac gacgcatccg gcgtctgccg atgacacctg ggacatcagc accaccggca
     8161 gcaccgccag tcccgatgcc agcccgatca cccccacgcg ttgacgacgt gggaccgtcc
     8221 tagccactgc gggccagccg ggtcagcgca gcgacgtacg catccggtcc cacacttgct
     8281 ccaccgctga acggatcctg cagctggtag atcgcgaaca gcatcagcgc gatcgccccc
     8341 gacaacatcg acacgatcac ggcgtacgag tagacgcccg gtccgccgaa catgaacatc
     8401 agcccgaccg acatcgcgct tcccaccaga atcgcgaacc acacgatcgc gctcaccccg
     8461 ttcccgctgg cattcaggcg gtcctgccgg gcctggtaca cgttccacag ctgcgtcgac
     8521 gcctcgatcc ggctgttctc ctcccggtcg gtcctcgtcg gaacgcgctc cacctcgccc
     8581 tgcaactccg acagcagctc ccagccctgc cctcccaccg gccctccggc ccgcagcgcc
     8641 ggccactcca cctggaccac ctcgttcgcg tacgactggg tcagttcctc gacccgcgac
     8701 cgggccggct cggccagcga ctcgctggcc cagcggaccg cgaccagcgc gttcgcctcc
     8761 tggtaggtgt tctcgtccgc cttgtcggtg gcgtcgaaca gcgagatcag cacgaacgcg
     8821 gcgatcacga cgttgacgcc gccgacgatg gtgaacacct gcccggcgac ctcgttgttc
     8881 gcctcccgcc cgaaccgctg ccgggccttg cgcaggatca cggccagaac cgcggtcacc
     8941 atcatcaacc cgagcaccca gaacagaccg ctgaagaaca ggctcatccc tggctccccc
     9001 tcccgctctg gacgcgaaac tcaccaggac cgacgcagcc ccggtcgcgc acagccccgc
     9061 tgcgcaccgc cactgggaga gtgaagtgca cggtctcccg cgtgatctcc cgctcgacca
     9121 catccaccgg accgaaggca gccagagcag cgaccacacc gtccaccaac cgtggcggcg
     9181 ccgacgcgcc ggcagtcagg ccgatcaccc tgaccccgtc gagccactcc ggccggagac
     9241 cggacccgtc gtcgatcagg tacgccggag tgccgcgtcg cctggcgagc tcgaccaggc
     9301 ggcgcgaatt cgacgagttg tccgagccga ccacgagaac caggtcggcg tcatcggaga
     9361 gcgctcccag tgcctcttgc cggttggtgg tggcgtagca gatgtcagcc gagtcggggc
     9421 cgcgcagcgc gccgaatttg gcgcggagcg catcgagaac ggcggcggtc tcgtccaccg
     9481 ccaaagtcgt ctgagtcagg taggagaccc gccctgcatc ctccacctcc agcgccgcca
     9541 cgtcgtcgac ggtctcgacc agaacggtcc ggtccggcgc ctcccccatc gtgccttcga
     9601 cttcctcgtg ccccgcgtgc ccgatcagga cgacggtgtc gccgcggccg gcgtaccggc
     9661 gggcctcggc gtgcaccttg gtcaccaacg ggcaggtcgc gtcgaccacg tcgagcccgc
     9721 gccgctccgc ctccgctcgg actgccgggg cgacaccatg agcggagaac accacggtcg
     9781 cgtccgccgg cacttcgtcg agctcgtcca cgaacaccgc gccacggctc tcgaggtcgg
     9841 ccacgacgtg agtgttgtgc acgatctgct tgcggacgta gaccggcgaa cgccgccggg
     9901 ccagcaactg ctccacgatc tcgatggctc gctcgacgcc ggcgcagaac gaccgcggcg
     9961 aagccagcag gatggtgcgt ctggtcatca gtccccctcc tcaacggtcg cgacgggtcg
    10021 cccatcgcgc cagccgctcc aggtcgtccg cggcgcccac tgcaccgctc gccgagcgca
    10081 gttcgccgag cgccgcagtc agcaacgcgt cggcctgtgc ctggctctgc gccttcgccc
    10141 cggcctcgtc gatcaacccg gccgcccgca ccagctcggc gtcggtcaga tcgcgcgatc
    10201 cctggtagag cgcggccagt tcctggccgg cagcggtccc cgacgtgagc gcggcgatca
    10261 ccggcagcga cttcttccgc cgccgcaggt ccgagtgcac cggcttgccc gtgactcgcg
    10321 gatcgcccca gatcccgagc aggtcgtcga cgtactggta cgcgagaccg agatcctcgc
    10381 cgaacagccg caggtgatcg acctgctcgg accggccacc accgaacatc gccccgagcg
    10441 ccgtcgaaca gccgagcagc gccccggtct tgagctgcgc catccggagg cactcgctca
    10501 gcgtcacgtc gttgcggatc tcgaagtgcg cgtcggcgag ctgcccttcg accagctcct
    10561 ggaccgcctg cccgagcacc ttcgccccgt cgtcggccgc cggctcacca ctgctcacga
    10621 ggacgtcgaa cgccagactg agcagggcat cgcccgccag gatggccggc ccgagaccga
    10681 acaccgtcca cgcggtcgcg cggtgccgcc gggtcgtgtc gcagtccatc acgtcgtcgt
    10741 gcagcaggga gaagttgtgc accagctcga ccgccaccgc ggcgggcacc gcggcggccg
    10801 tcgtaccgcc gaccgcttgc gacgccagca aagccagcgc cgggcgaagc gccttgccgc
    10861 cgtcggcgcg ggtcggcgtg ccgtcctcgt cctcccagcc gaagtggtag ttggtgatcc
    10921 gctgcgttgc cagcggcaac ttgccgaccg cggcccgcag cgccggctcg acctggtccc
    10981 gggaccagcc gagtgcccgc tgcgcgagga ccctgttcat cgcgtcacct gacgtggtcg
    11041 ctcccgtgcc gtccgtcgta ccgctcggtg gactgtccgc gggatcgagt cgttcgagtg
    11101 tcgtcatcgt ctctcctcat ccaccgagct cgacgttctc cagcacaccg agagcgtccg
    11161 ggaccagcac cgccaccgag tagtaggtgc tgaccaggta cgacgtgacg gccttctcgt
    11221 tgatttccat gaaccgggcg ttgagtccgg gctcgatctc gtccggcaac ccggtctgcc
    11281 gcagaccgac gacaccttcg tcctccaggc cggtccgcag cacgatcacc gacgtggtgt
    11341 tgtcggcggc gatcgggatc ttgttgcagg gcaggatcgg tacgccgcgc cacgcctgca
    11401 cccgccggcc ctcgacgaga gcgctttccg ggtagacccc ggccttgctg cactcccggc
    11461 cgaaggcggc gatcgcccgc gggtgggcca gcagcgcccg gggcttgcgg cgccgggtca
    11521 gcagctcgtc gaagtcgtcg ggggtcggcg gaccggtgcg cgggtagatg cactgcttga
    11581 agtccgcgtt gtgcagcagg ccgaactcgc ggttgttcac catctcgtgc tcctggcgtt
    11641 cccgcagcgc ctcgatggtc agccgcaact gctgctcggt ctggtccatc gggtggttgt
    11701 agagatccgc gacccgggtg tggacccgca ggatcgtttg cgcgacgctc agctcgtact
    11761 cccgcggtgc cgggtcgtag tcgacgtagg tgccgggcag gtccgcctcg cccgcgtgac
    11821 ccgaagagag cgcgatctcg gcctctccgt tcttgttctg ggccggacgc ggccgggacc
    11881 ggagctcgtc caggtgctcg cgcagtacct cggaccggtc cctcaactgc tcgagcgcct
    11941 gacgagtcag ccgcagcacg gtgcaccggg tggtcgtgcg ggcggtgtac tcccagatac
    12001 tttccggtgg atcggtgaac aactgctcgc cgaggtagtc gccgtccgcg gccgtgccca
    12061 gatcggtccc gtcaccgtag cgcccgatgc cgatcttgct gatcttgccg tgggcaatca
    12121 gaagcacgtc gtcgatccgg ctgccgaact cggtcagcac ctggcccgcc tcgtactcct
    12181 cctgcccgaa gcggttcgcc agttcctgca gtacctccgg atcctgcagc tcgcgcagcg
    12241 gcggcagctc ggtcaactcc tgcgggatca cccgtacgtc ggccccggtg gcggagaagg
    12301 tcagccggcc gtcgccgatc gcgtagctgg tccgccggtt cacccggtag gccccgccct
    12361 tggtctccac ccagggcagg atccgcagca gccagcgcgg cgagatgcct tgcatctgcg
    12421 gcaccgactt ggtggtggac gccagttgcc gcgccgccgc ggtccccagg ctgagctgcg
    12481 gcctggtctg ggtttcggtc tcggtctccg aggtggtcac agtgcaccct ccagtcgctt
    12541 catggccaag gaccgtccga tggattcggc agatgtgccg aggccggtcg cgccgccgag
    12601 cagcttgcgc ggcagatgca gctgcgcgcc ttcgtcgtac cggcggcagc cggcgtgcca
    12661 gacgagaatt cccgacatcc agttctgcag ctcctcggcg tacccggtga gcacccgtcg
    12721 gacgtcgtcg ccgagctcgt agtcgtcgaa cagcaccggc aggtccaccg cgaccagctg
    12781 ctcgaactgc cgcatccgcg cggtcatcag ctcgttcacc accgcgaacg ccgtgctcag
    12841 gtcacagtcg agaaagttcc gcacaaccag gaccccgttg tgcagctcgc cctcgtactg
    12901 gatttccttg cggtacgaga acacgtcgtt gagcaggcac gcatagtccg cggccgcgct
    12961 ctccagcgcc cggatcgggc gggtccggta gatctccggc ggtaccgtgc ggccgtggcc
    13021 gatccggcac aggctcatgg tgagatcgga gccgaacgtc cgccggcgca tttccaggta
    13081 gtcgaccgga tccgggatcc ggtgctggaa ctggttcgcc agctcccaca gccagctgtc
    13141 gatcatcgtc tcgaccgcgt ccttgaatgc ccgccgcgcg tccggtgcca tcggccccgc
    13201 ggtccggctc cagagatcgg ccagagagcg ctccagcgcg ttcccgggca ccggcggccc
    13261 ggcagcgtcc agctccaacg gcatcagcgc cgacaaccgc ttgtttgtcg ccttcgcacc
    13321 gaccaggtcc cgcgaccggc cgaacgccac cgggtagtag tcgtcggcat aggtgcccca
    13381 agcgagccac tggctggaca ggtccaacgc atccgggtcg gcatccgggt ggatccccgc
    13441 cgcgcacaac ggcaggtcgt tggcgagcaa catgcgcgcg tcccagatga ccccgtcggt
    13501 gagtcccatc cgctgacccc actcgagcac gttcgcccgt gcccggtcga ggtggggact
    13561 gagcttcgcc cggtacggca tgtacagctc cggccgctcg aacggctcga ccacgtcgta
    13621 caggcgatgg gtgtagctgc gaatccggta cggcgccgac gtcaccatcg actgcaggat
    13681 tcggctcgcg gccgtgccga gccctttcgg cccgtcgagc aacgcgctcg gtccgagcgt
    13741 ggccgcttgg ccgccgtcgt tcatgtagcg gctcgaccgc aggtgccact cgtgcccacc
    13801 cgactgccag tcctgcagac ccttcacata gctcagaaca tcgagccggc cctgcggact
    13861 gattcggtgc tccgccagca gcggcggcac ctcggtgagc gcagtgttct cgaactggtg
    13921 cagtcgcgag gtgaggatgt cgttcaccag atccgccgcc cgctgcggag aacagccgag
    13981 aaagcgctcc accaccagca cgccgttgtt cagctcgccc tcggcctcca cctcgcgctg
    14041 gtacgagaac aggtcgttgc gcaggtgcac cgcgtcggag aacgtgtcgc tgagcacctt
    14101 cagcggccgg gcgtgcgcga cctcctccgg cacctccgcc tggacggcgt actcgaccag
    14161 gttcgccgac cagggcgcgc cgccgacctt gcggcgcatc tcgacgtact cgatggggtt
    14221 cggcaaccgg ccggcgctga tgttggacag ctcccacagc gactccgcca gcaggctttc
    14281 cgtggtcgcc gcgaaccggc gccgccagcc ctccgacatc gacggcacgg tccgggccca
    14341 gagatcggcg agaccgcgct ccaccgggtt ctcgggcgtt tccgtgatcg cgccgtcgac
    14401 cggcatgaac gccgccagcc ggttcaggta cgccttggcg ccggcggtgt cctgggtctt
    14461 cttgtagagc tccaagaagt gatcgtcgaa gtagaagacc cagacgtacc agtcggtcac
    14521 caggtcgagc gccgcggcgc cggcgtccgg gtgcgtgtaa gcgcagagca gggcgtagtc
    14581 gtgggagtcg aaatcgcgca ggtcccagat cgccttgccc tgctggggaa cgtcgatcat
    14641 gtcgaacgcg tacgcccagg cccggctgtg ctcgcgcgcc tgctccaggt gcgggttgat
    14701 ccgcgccggg tacggcacgt agaactccgg caactggtac ggctgtccgc cgctcggcgc
    14761 cgcgcgttcg cggctcgggg ctggctgtcg ggcgttggac gtgggctgtc cggtcctgag
    14821 ggtcgattgt ccggtgctcg gggtcggccg gcccgtgggc ggcgaaccgc ccttggtcag
    14881 gccgcccggc tcgtctgtcg cgtcccgccc gacgtgggag acgagccggg cggcggctcc
    14941 cggcggttgt ggcgctctca cctcccggtc ctagctctcg cgcccgatct cgacgtcctc
    15001 gagaatgccg agagcgtcgg ggaccaggac ggcggccgag tagtacgcgc tgaccaggta
    15061 gttgatgatc gccttctcgt tgatgttcat gaaccgcacc gacagccccg gctcgtactc
    15121 gtccggcagc ccggtctggt gcaggccgac caccccctgg ctgtcctcgc cggtgcgcag
    15181 cagcatgatc gagctggtcc gggtctcgct gatgccgatc ttgttgcacg ggaagatcgg
    15241 tacgccgcgc caggccggga cccggtggcc gccgaggtcc acgctgtccg ggtagacgcc
    15301 ggccttcgtg cactcccgcc cgaacgccgc gatcgagcgg ggatgggcca ggaagaaggc
    15361 cggctccttc cagaccatgc cgagcaactc gtccaggtca ccgggcgtcg gcgggccggt
    15421 ccgggtcggg atccgcatgc tcaggtcagc gttgtgcagc aggccgaact cgcggttgtt
    15481 caccatctcg tgctcctggc gttcccgcag cgcctcgatg gtcagccgca actgctgctc
    15541 ggtctggtcc atcgggtggt tgtagagatc cgccacccgc gtgtggaccc gcagtacggt
    15601 ctgggcgacg ctcaactcgt actcgcgcgg cgtggtctcg tagtcgacgt acgtaccggg
    15661 cagctcggcc tcctgctcgt gcccggacgc cagcgcgatc gccgcctcgc cgtactcgtc
    15721 ctgtgccggc gccgggttcg cgcggaacgc ttcgacatgt gcgcgcaggc tgtcggatcg
    15781 cgcgaccagg tcctcgaacg cgtcctgcga cagcgacagc accgtgcacg gggtgatcgc
    15841 cttgacggtg tactgccagt ggtcctcgga ctcgagaagc gcctggtagg cgaagtggtc
    15901 cccgtcggtc agcgtcgaca gcacggtctc gtcgccgtac ttgccggcgc cgatcttgtt
    15961 caccttgccg tgcgcgatca ggcagatccg gtccgcgggc cggccgcgct cgaccagcac
    16021 gtcgcccggc tggtactcct gctgctcgaa ccggccggcc agctcggtca gcacctcgac
    16081 gtcgtcgaag ctgcgcagca gggccagctc acacagctcc tgcgggatca cccgcacctc
    16141 ggcgccggtc gtggtgaagg tgacccggcc gtcgccgacg gcgtaactca gccgccggtt
    16201 cacccggtac gcgcccccgt tcacctgcac ccagggcagc atcttgagca accaccggga
    16261 ggtgatgccc tgcatctgcg gctcggactt ggtcgtggtc gccaggttcc gcgcggccgc
    16321 ggttccgagg ctcagttgcg ggcgctgcac ttgggcgtcc gaggacgccg gttgggtcat
    16381 ggtcacgcgg taagcaccac ctgtcggttc ggaccgccca ggcgcagcac gcaccgcacc
    16441 ccgggacgcg gggtgtgggt tcttcggtgg gtggaggcgc gcgggcaggc aggaaggaac
    16501 ggctcgtcga ctgcgtggac gctccagccg gcactgttcc cgtcgtcggc ggcaacaccg
    16561 gcgcgggacc ggacaggccg ggctgcgacc gctcagggct cccagttcgc cctgcccggc
    16621 cagtccggct ggaaacgcaa cacaccgtaa ccggaccatc accgtgtgcg tcaaggggcg
    16681 cacacagtga caatcttgcc aagtcctggc gaccacgtat taattgctca cggcacccct
    16741 ggtcaatgcc ctcggccccg atctgcaccg cggccgatgc accgggcaac cgaccggtca
    16801 gatgatcggc gtctccggag cggttgcctt cggcgtcccg gcctcggcgg ttccggacag
    16861 ctcgtcgacc tcgatccggc cggtccagcg caggtcgggg tcgggctgcg ggatggagtc
    16921 gagcagcagc cgggtgtacg ggtgggacgg ctcgtgcatc acggtgtcga ccgggccgcg
    16981 ttccacgatg acgccgcggt tgatcaccat cacggacccg cccaggtagt acacggtcga
    17041 caggtcgtgg gtgatgaaca gggtcgtcat gccgtactcg cgctggaagt cgagcaggat
    17101 gtcgaggaac agccggcgga cctgggcgtc gagcatcgag accggctcgt cggcgatcac
    17161 gaaggccggt cgcagcatgt ggatccgggc cagcatgacc cgttgccgct ggccaccgga
    17221 gagctggtgc gggtaccggc cgagcacgcg ctccggctcg agcttcaccg cttcgagtga
    17281 ccgctcgata agagccagcc cttcggaccg gctggaggcc aggccgaact tcttcaccgc
    17341 cttccacagc acccggtcga cccggtagaa cgggttgaag atcgcgtacg ggtcctggaa
    17401 gaccggctgc acgttgcgcc ggtagtcgtc gtactcggcg cgggtgagct tgaagatgtc
    17461 cttgccgccg taccgcacgg tgccgctggt cggcttctgc aggccgagca cgttgcgggc
    17521 gatcgtgctc ttgccgctgc cgctctggcc gaccaggctg accacctgcg gcggctccgg
    17581 ggcgagcgtg aaggtggcgt cctggaccgc ggtcaggtag ccgccgaccg cgccccgggc
    17641 gtggaatcgt tgctggacgc cactgagctc gatggtcttg gtcacgatgc cctccggccc
    17701 actagcggaa tcgattcgat cagctgccgg gtgtactcgt gccgcggctg cttgtagacc
    17761 tgccgtacgt caccgacctc gaccaggctg ccttcgtaca tcaccgcgac ccggtcggcc
    17821 agctgagcgt gcacgcccat gtcgtgcgag atcaccatca gggtcacgcc gaagtcgcgt
    17881 tgcaggtcca ccaggctctg caggatcacc cgctggatcg tgacgtcgag cgcggtggtc
    17941 ggctcgtcgg cgatcaccag gtcgggttcg agcgcgacgc agatcgccat cagcacacgc
    18001 tgcttcatgc cgccggacag ctcgtgcggg tacatccggg cgaccgccgg ctccagcccg
    18061 acctggccga gcaaccgtgg gatcagctcg gagagcgtgt ccttgcgttc cggggcgtgt
    18121 tccaggatca cgtcccggaa ctggtcacca attcgcatca ccgggttgag cgagctcatc
    18181 gagccctgcg gcaggtagga cagcgcgctc cagcgcagta cccgcagctc ctcgccggag
    18241 accttcagca gatcaacggg agaacgtccg cggggacgga agagagcgct ccccgccatc
    18301 accttgccgg gtggtttgag caaccgcagc agcgccacgg cgagcgtgct cttgccgctg
    18361 cccgactccc ccgcgatgcc gaggatctcg ccgcggcgga ccgcgaggtc caggccgcgc
    18421 accgccttca cctcgccccg gttggtcgag tagccgacct ccaggccgga gatctccagc
    18481 acgatctcgt cgtcactcac cggcaactcc tctcagccgc gggttgtaga cctcttccag
    18541 tccgatgtta atcatgttca acgccgcgaa cagcaacgtc agcagcacga tcggcaccac
    18601 gaacatcggc caggcaccga gcgtcagcgc accggtgttg atcgcgttga agatgatctg
    18661 gccgagatcg atcacgccgc ccggcccgag tccgatcacc tccagcccga ccagcccgaa
    18721 gatcgcgccg agcgccgagg aggcgaaccc gacgccgatg aacggcagca gattgggcag
    18781 cagctcggtg gcgatgatct ccaggtcccg ggccttgctc acccgggcca ggtcgacgta
    18841 cgggcgcgac cgcaggctga gcacctgcga gcggatcgtc ttggccgcga acggccagct
    18901 gaagatcgag atcatcacgc cgacctggaa caggctgacg ttcttggcgt acgcggagag
    18961 cgcgatcagc agcgggaacg tcgggatcac cagcaggatc ccggtgaagg tggacagcac
    19021 accgtccacc cagccgccct tgtagccggc gacgaaggcg accaccacgc cgaccacggt
    19081 ggagatcacc ccggcgatcg caccgatctg gagcgacacc gacagcgcgc tgatcaccat
    19141 cgccagcacg tcgcggccgt actggtcggt gcccagcagg tggtcggccg aaggcaccag
    19201 ccacttctcg tacgccgcca gctcgatcgg gtccgtgccc ttgccgatgg catcgaccag
    19261 caccgggctg agcacggcca gcagcaccat cagggtcagg atcaccagtc ccgcggcgag
    19321 ccggtgactc tgccgcacgg ttttcactgt cgcggtgagg agacgcatcg cgatcacttc
    19381 cagtacttga cccgagggtc aagcagcggt aggaggaggt ccagcaggag aacggcggtg
    19441 agcaccgaga agatcgcgat gtcggtcacg ccgatgatcg tgttgaagtc gagctgctgg
    19501 atcgccgtca ccagggtggt cccgagcccc gggtagttga acagctgctc gaccagcacg
    19561 ttgccgttga agatgaagcc gagcgagatg ccgaacgcgg tcacctgcgg caggtagcag
    19621 ttgcgcagcg cgtaccgggt caggatccgc cacggcttca ggcccttggc ttcggcgtac
    19681 accaggtagt cctcgccgag caccgggacc atcagcatcc gggtggacag gatccagccg
    19741 aaggttccga tcagcatgat cgagaatccg ggcagcagcg cgtgcttgag cacactcccg
    19801 atgaagtcgg cgctgatccc gggactgatc gcggagtcgt acgccgaccg ggccggcagc
    19861 atgccgaggg tgtaggcgaa gacgtagacc aggatcagcg cgacgaagaa gaacgggacg
    19921 tgggccagcg cgatcgacag gttcgtggtg atcgtcgatc ccagcttgcc gcgccgccag
    19981 ccggcgatcg cgccgatgac gaggccgagg atccacgaca tcaccgcggc gacaccgagc
    20041 agaccgatgg tccacggcaa cgagtgcatg atgacgtcct gcgccggcgt cgggtagttc
    20101 agcagcgacg gacccaggtc gccgtgcagg atcaggttct ccatgtactt caggtactgc
    20161 gagaagatgt tgccgtccag cccgaactcg tgccggtacc gctcgatgat ctcctcgctg
    20221 gcctgctggt tgtagacgta gttctgctgc agggtctgga tcagcgtctg gatcgggtcg
    20281 cccgggatca tccggaagaa gaagaacgcg atcgtcagcg ctccccacag ctcgaccagg
    20341 tagagcccga accggcgcag cgcgtacgcc gccagcgggt gccgcgccag ccaggcccgg
    20401 ccgccccggg agggagcgct ctccgcgctc tctcccacca cggtctcggc cggcggcgcg
    20461 gtggcggtca cgccgggccc ttctgcccgg tcgccttcag ccggccgagc acgaagatga
    20521 agtgcgacca ccagttcagc ggcacctggt acaggtcgtc gtcggtcggc catccggtcc
    20581 agaaggcggt gttgaagaac gacgggtacc cggtctggat caccggcagc aacggcaact
    20641 gctggaagta gagctccagc gcctcgtcca gcagcggctt cgcctcgggc gtggtcgggt
    20701 ccagctggga cagcttgagc gacagctcgt ccagcttggg gttcctcagc cgcatcttgt
    20761 tcttgccggc cgcgttcttg ccgatcggct gcgccttgct gctctcccag tcggtgtaga
    20821 gctgttgcgg gtcgaaggcg aagccggccc agttcgagtc gatgtcgtac tcgccgcgct
    20881 ggaacttctc gtcgtgcaca ctgccggtca ggctgcgcag cgtggccggg acgccgacct
    20941 tggcgaggtc ggtcttgagc acgtccgcga tcgcgtactc gtccttgttc accggggccg
    21001 gggtgatgat ctcgagattg atctccttgc ccttgtacgt ccgtctgccg gccgcgttct
    21061 tcggcgcgat ctcgtccagc agcgcgttcg ccttgtccag gttgtactcg aacttgtacc
    21121 tctccgcgag ctcgtcgttc ttccacttgt cgttgctcgg gtagtccgcc cacgggtaga
    21181 tcgcggccgg gacctcgacc tgccagatcg acttgccgat cttctcccgg tccaggcagt
    21241 ggttgatggc ccagcgcatc ttcggctcgg cgatgacacc gcgggccggg tcgcagttca
    21301 gccacagcac ccgggggttc gggtcgtgga actgagtggt gaccaggtgc gggtagccgc
    21361 cgttgcgcag ctgcttggcg tgctgctcgt cgatcgagcc gacgtcgaac tcggcccgct
    21421 cgaacgccag cgacgccgag tccgcctgct tggaggtgct ctggtagacc acgtactgcg
    21481 gtgccgggtc cagctggtcc ttggcccagt agtccgggtt cttctcccag acgaacatct
    21541 tctggctccg gatcgcctgc ttcagcttgt acggccccgt ccgggtcggc gggttctcct
    21601 tgaacttggt ggggtcctgc cccttccaga cgtgctcggg caggatgtcg aacccgctgg
    21661 cgatcgcggc gacgaaggtg tagtgcagcc gcggcgtcgc cttcttcatc ttgatcaccg
    21721 cggtgtgctg gtccggcacc tcgacgtcct gaacgaactc gcccaggtcg ccaccgccac
    21781 cgaacaggtc cttgcggtcc ttgagcagca tcacggtgaa ccggaagtcg ttcgcggtga
    21841 gcggcttgcc gtcgctccac ttcgccttcg ggtcgaacgt gaacgtcagc tgggtgtgcg
    21901 agtcgttgta cttgtagccg gtggccagcc acggcttcag ctcgccggtg gccaggttga
    21961 ggtagaacat cgcctcgcgg cagaccgact cgaacccggc gccggactgc cagccgttcg
    22021 ggatcatcgt gttgaagctg tcgaacacgt tgtactcgac ctggccgacg accacggtct
    22081 ggtcacgcgg cgtggggatg ttcgccttgc cgatctgcac ggacttggtg gcggcgggct
    22141 tgttcgccgg cttgtcggag tacgagccgc cgctcccgga gcaggcggcc agcaagccgg
    22201 ccagaccggc cgcggcacct cctccgacca ggctgcgacg gctgagctgg tagcgcagga
    22261 catcggcgac gtcctcgaac tgcgggcgcg gggcatcgtt cactttcgga actccttcgg
    22321 tccggagagg gctcggcctg gccgcggcgc gggccggttc gacggcggca cggcgtccgg
    22381 gggccgctgt gacgcaagca cctccgtttc gcttgcccag gggcggggga tgactgcccg
    22441 aaacgtttcc aggactatag gtagcgatga caacgatggc aatacttcgt tggcaggttg
    22501 gccgttgtgc tcggattacg actgcgcaac ggcgaagcgg ggactgacaa cgaaagttcg
    22561 cgttgcgtga tcgtcggcgt cacacggtcc gtcacacggc gagcgcgttg catcggcatc
    22621 gtcgccggac cgggcgacgt cccgggacgg tcccgggcca cgtgtcaccg ggggacgcac
    22681 cagttctagg gggaacacgc atgacgagta ccgctgtcga tttcgcggcg atcaaggaca
    22741 agcagcgcgc gggctggcag accggtgact acccgcgggt cggcaacacg ctgcagatca
    22801 tcgccgaact gctggtcgag gcagccgacg tccgggccgg gcaacgcgct ctcgacgtcg
    22861 cctgcggcca gggcaacgcg gcgatcgcgg cggcccgccg attcgctgag gccaccggcg
    22921 tcgactacgc cgccaacctg cttgcccagg gccgggaacg cgcggccgcc gagcacctgg
    22981 acgtcacatt caccgaaggt gacgcggaga acctgccggt gccggacgct tcgttcgacc
    23041 tggtgctcag cacagtcggc gtgatgttcg ccccgaacca tcagcaggcg gccgacgagc
    23101 tcatccgggt gaccgcgccc ggcggcaaga tcgcgctctc cagctggacc ccgaccggca
    23161 tggtcgggca gatgttcaag gtggtcggca agtggactcc gccgccggcc ggggtgaagc
    23221 ccgccgtgtt gtggggtacc gaggagcacc tgaccgagct cttcggcgac cgggtgcagt
    23281 ggatcgcgct gaacaagcgc gagtacgtct tccgctacca ctcgccggag cacttctcgg
    23341 agtggttccg ccagttctac ggcccgatca ccaagctcgc cgggtccctg tcggagcaag
    23401 accgcgccac gttcgcggcg gagctcgccg acgtgccgcg ctccttcaac caggccgatg
    23461 acggaacggt ggccgcccgc gcggagtacc tggaagccgt gggcgtacgc cgctgaggct
    23521 cgccgggaac gcgcgatccg ggcgatcccg gcgtgcgcgg ggtgcggggt gcgcggggtg
    23581 cgcggggtgc gggggtgcgc tttcgcggcg tacgcggtgt gctgacgttc gcgtcgttcg
    23641 cgtcgttcgc gtcgttcgcg tcgttcgcgg tctgcacggc gtgcgcggcg ttcgcggtcg
    23701 gtgcggcgtg cgcggtctgt gcagtctgcg cggtgtgcgc gttagcggca tgcgcggcgt
    23761 ttgcgccgtt cacgctgttc gtgccgttcg cggcgttcgc gctcttcgcg ccgttcccgg
    23821 tctgcgcggc gcgcgcagtc tgcgcggcgt gcgcggtctg cgcggtgtgc gcgcgttcgc
    23881 ggcgtcgagg agggtgaggt acgacaaccc gcttccgcgc tgccggcaga tctcccggca
    23941 gcagcagcgc gtcggcgtgg ccgcgatcgt gctgccgctg cccggcgtac gggtcgacga
    24001 ttgcttgccc ctggcggatg cggggcgcgt ggagatgagg ccggccaggg gcggagttgg
    24061 cggtgacatc accggggtgg tgggtccaca ctgaagggcg ggggtgggac tcatgatggg
    24121 cacgatccgg ctgctcgggc ggccgacgat cgagtacgac ggggtggcgg tccggtcgcc
    24181 gcgcggccgg aagagctggg ccctgctcgc ttacctgctg ctcaccgaac gcccaccgac
    24241 ccgcaagcgc ctggccgaac tgctgttcgc ggacgccgcc gaccccctcg gcgccctgcg
    24301 ctggagcttg gcggaactgc gccgcgccct cggcgtaccc gacatcctga ccggcgaccc
    24361 gatcgtcgca tcccttgaaa acaagctgat cgtcgacgtg ctggaagtgg ttgacgcgtc
    24421 cgacgccgcc aggttgctga ccgtcaacgg tgagctgctc gaaggcgtcg acctggccgc
    24481 gtgcccggag ttcgagtcct ggctcctggt cgaacgccac cgagtagcag ccgccctgga
    24541 agcccgcctc cgtgaggtcg ccatgcgact tgtggcggcc ggccgcggac acgacgcgat
    24601 cgccttcgcc gcccgcgcag tcgacttgaa ccctttcgat cagggcaacc acgagctcct
    24661 ggtccgcagc ctcgcggtcg ccggagatcg ccgggcagcg ctccaccagg tggcagtctg
    24721 tgacgacatg ctcaaccgcg aactgggcat cgagccatcc gccgccctcc gagaggcagc
    24781 aaccgcacca gaagaccgac tagacgcatc acggcacagc gcggacgcac cacaaccgtg
    24841 gtcggccgga gcacagtcgt cgtgcgatac atcgcccgca tctcccaaga cgccccgcgc
    24901 acggtcgccg atcaacgagt tgccagcggg gccggctgtg gcgccagggc gcgacacggc
    24961 a
//
