LOCUS       NC_013729              24280 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Kribbella flavida DSM 17836, complete sequence.
ACCESSION   NC_013729
VERSION     NC_013729.1
KEYWORDS    RefSeq.
SOURCE      Kribbella flavida DSM 17836
  ORGANISM  Kribbella flavida DSM 17836
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 7579488)
  AUTHORS   Pukall,R., Lapidus,A., Glavina Del Rio,T., Copeland,A., Tice,H.,
            Cheng,J.F., Lucas,S., Chen,F., Nolan,M., Labutti,K., Pati,A.,
            Ivanova,N., Mavromatis,K., Mikhailova,N., Pitluck,S., Bruce,D.,
            Goodwin,L., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D., Chen,A.,
            Palaniappan,K., Chain,P., Rohde,M., Goker,M., Bristow,J.,
            Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C., Klenk,H.P.
            and Brettin,T.
  TITLE     Complete genome sequence of Kribbella flavida type strain (IFO
            14399)
  JOURNAL   Stand Genomic Sci 2 (2), 186-193 (2010)
   PUBMED   21304701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Kribbella flavida DSM 17836
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024345.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,131
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 7,033
            CDSs (with protein)               :: 7,033
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 8 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 4 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name             :: Kribbella flavida DSM 17836
            Culture Collection ID :: DSM 17836, JCM 10339, KCTC 9580, NBRC 14399
            GOLD Stamp ID                     :: Gi02235
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: GeneMark
            Isolation Site                    :: Soil from China
            Isolation Country                 :: China
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:11:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4135553
            Orig. end                         :: 4159833
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001736.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082793
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24280
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24280
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24280
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14280](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14280)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    129..143
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            371..2221
                     /locus_tag="KFLA_RS19130"
                     /old_locus_tag="Kfla_3851"
     CDS             371..2221
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1214:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="KFLA_RS19130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3851"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_012921460.1"
                     /transl_table=11
                     /translation="MVITDARPPTVPPPDAGPPRRRGRWRYRLSVARHEPTLLIGLVLI
                     LLLLYLVIAPLVAVLSDAVRVQFGDQPKTGQQPGELTGYYLWRVFRSQVSSIVFWQPLV
                     NTLVVAVGVTVLALLLGGICAFLLTRTNIAGRKWLSTALVVPYMLPSWTFALAWLALFK
                     NDRSGGQVGILEARGVQTPDWLAYGAVPIIVCLGLHYFPFVLLLFGNALRRLDAQLEDS
                     ARILGAGRGTVLGRITLPLMLPSLSSSTLLVFGRILGTFGTPYVLGLPVDYTLLSTSLF
                     SAVRNHEPGITAVIATVIVVIGVAVVVADARLLREQRRFVTVGGKGAMDRIIELGRWRW
                     PAGGVALGVFALSVVVPVVTLALTTVTTTPGVFSAENFTLKYWLAEDLPGAPGFPHGIL
                     RGTELLDAAWNSLRIVGLASLVCGVVGLLVGYVVVRSDGSRIASVLRQVSFLPYLVPGI
                     AFAAAFLSLFAVRRGPVPALYGSVTLLVIVLAVTHLPYASRSGISAMTQLGREPEEAAQ
                     VTGAGWLTRVRAVVVPIQRGSLVTGIVLPFISGIKELSIVIMLTTTGTQLLTTLSINLI
                     DFAYDQMANAVVLVIALVAFLATYLTQRLTRTSLASGLGG"
     gene            2226..3371
                     /locus_tag="KFLA_RS19135"
                     /old_locus_tag="Kfla_3852"
     CDS             2226..3371
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="KFLA_RS19135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3852"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012921461.1"
                     /transl_table=11
                     /translation="MPTIALQSISKSYGVGPLAVQDLDLTIPDGSFTCLLGPSGCGKTT
                     TLRMIAGLEHPTAGSITVGGRVLDSVEQGTFVPTERRGMGLVFQNYALWPHLTVRRNVE
                     FGLRVQKVPAAERRTRVDAALAMMQIATVAERYPSQLSGGQQQRVSLARMLAVNPSVLL
                     LDEPLSNLDATLRLEMRAELKRLHEETGHTIVFVTHDQLEAMTMATQVAVMKDGVLQQL
                     APPMDVYHRPANVFVAAFVGSPPMNLAPCDAEGDGLGGLARQYLQLAQVGPVDRVATVG
                     VRPEAVRVVDAGHPGSERELAFDGQVRAVLPTGAAWTVSLTVGSTELYLVSTDEVDATT
                     GNTIRCAVQRKALHVFGPDGDRLNLGSGRDAEREEVAQWVS"
     gene            3359..4129
                     /locus_tag="KFLA_RS19140"
                     /old_locus_tag="Kfla_3853"
     CDS             3359..4129
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012905.4"
                     /locus_tag="KFLA_RS19140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3853"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_012921462.1"
                     /sec_met_domain="HAD_2 (E-value: 2.2e-16, bitscore: 59.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQLITPEALLLDFGGVLVATTGRPGWAGELAAELSDQLSRAGTP
                     ELTVDEIRTDLEAGAAADSYWKNAMSRPPTPRELTHREFWTDFVAADWPPGPRAWVTAH
                     ASVLCRRMGELRQHRAHREGIPELLDTAAAAGIPVGVVSNALSGAVHRDYLERTGLVKQ
                     LAVQIYSDEMGIRKPHPELILLAARALGVPVGRTWYVGDNFDRDVLCARRAGAGAAVLM
                     EAPGTYQRPYAVRAVPDAIVPDPVALRTLLLEAL"
     gene            4152..5012
                     /locus_tag="KFLA_RS19145"
                     /old_locus_tag="Kfla_3854"
     CDS             4152..5012
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006020 - inositol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0046855 - obsolete inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020387140.1"
                     /locus_tag="KFLA_RS19145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3854"
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_012921463.1"
                     /transl_table=11
                     /translation="MTTTPGTDARPDPELTASSRELRELAGQAVRLVADDLRAAFRGAI
                     AVQYKRDRHDPVTEHDRRAEKAIAELLTGRAPGSTVVGEEDGTSAGNGAVTWYVDPIDG
                     TANFAHGLAFFCTSIGAVVHGRIVAGAVLDPVADHLFTADLTGAWLNGRPLRSRGVIEE
                     AQALLITSYPNARALESDGTEGLAWFGELVAGYGTVRRPGSAALSLCHVAAGWADAALG
                     TSVSAWDICAARLIVEQSGGRYHGFGGSGWDQPGYAAHTADLEPTVLRGFVDAFPARPD
                     GEAQA"
     gene            5009..5809
                     /locus_tag="KFLA_RS19150"
                     /old_locus_tag="Kfla_3855"
     CDS             5009..5809
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179: hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /locus_tag="KFLA_RS19150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3855"
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="WP_012921464.1"
                     /transl_table=11
                     /translation="MTPQLRYPWLVTDLDGTLVDRDLEIPARNLEAVDRYRAAGGTVTI
                     ATGRNERSAGRYHAQLGLDTPLILYNGARIVDLASGRRLLDLTLGEAWPLVAARALPRL
                     PSAVGAVGFHDLDAYVLKPAPALTQYAGRDQIQLVETAPPGSPTKLMLIAESPGELDQV
                     AELIASVTIAVRLVRSEKTYLEILPANADKGSALRALVASAGVSLDQVAAVGDNPNDLE
                     LIQTAGLGAAVADGHAEVVRTADVVVAACSDAAVADLIDRYLLC"
     gene            complement(5819..6562)
                     /locus_tag="KFLA_RS19155"
                     /old_locus_tag="Kfla_3856"
     CDS             complement(5819..6562)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024583.4"
                     /locus_tag="KFLA_RS19155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3856"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_012921465.1"
                     /transl_table=11
                     /translation="MEIPQQRQRSDRPPHRPTAGSTEFAADLGKLARTLQETEEPDAVL
                     KEAVRGAIELLPPVVAGSVTLPAGPERVDVKAASSELAMRIGAVLTDLGEGPSLDALAS
                     RQTVRAARLADDERWPRFAVPVLELGVTGVLCLPLYVDDRTLGVLNLYTLDPDGFTAED
                     EQAGQALAIQAAVAYAWAQRTEQLLTAVETRDLIGEAVGLLMERYSIGADRALGMLRQC
                     AHQSDRDVVDAAHELIRDAETGFRH"
     gene            complement(6665..7690)
                     /locus_tag="KFLA_RS19160"
                     /old_locus_tag="Kfla_3857"
     CDS             complement(6665..7690)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040247.3"
                     /locus_tag="KFLA_RS19160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3857"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_012921466.1"
                     /transl_table=11
                     /translation="MGRTHEVSTAIGRRWPDRWPLQWLPRQPWARQQPTYRDASPALIE
                     AAVKRASVRPSGNWFVFAASRDVGTKTPFGAEVGGTELVAWRCPDGTLRVGPGACPHLG
                     APLALGKVECGRVVCRWHGLSVGDDDDRTGWLAYPSHDDGVLCWVRLDRVGGEEPTDLP
                     LVPERPAGACLDAVATMSGQCEPIDIVANRLDPWHGAWFHPYSFSDLRVRELPQGGDDA
                     GDDKFVVDVTFRLGGPIGVPVRAEFTCPGPRTVVMRIAEGEGAGSVVETHATPLGPGPD
                     GRPRTAVIEATVAASDRPGFAVARHAAPALRPAMRWAAGRLWRDDLAYAERRYHLRTRG
                     R"
     gene            complement(7693..9261)
                     /locus_tag="KFLA_RS19165"
                     /old_locus_tag="Kfla_3858"
     CDS             complement(7693..9261)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580020.1"
                     /locus_tag="KFLA_RS19165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3858"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_012921467.1"
                     /sec_met_domain="DAO (E-value: 1.7e-08, bitscore: 33.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGRPPWAGSDRRIVRHPVPAATGPRGARQPRVVVVGGGIAGLS
                     AATVLAERGVGVVLVEREPYLGGRVGAWPDQLGDGSTVTMSRGFHAFFRQYYNLRRLLA
                     RTDPALERLTPVADYPLMDPEGRTDTFRGIPRRPPWNALAFAVKSPTFSVPDLLRLNAR
                     AALPLATVRVPRIYEQLDGTTAEELLDAINFPPAARHLAFEVFSRSFFASPKELSAAEL
                     AVMFHLYFLGSSEGLLFDVPTDTFAISLWDPLGGHLAELGVDVRTGTSVHTVEPGGERK
                     YRVHTGDGAVDADGVVLATDPRALRDVVQASPELGDPGWRENVARLRTAPPFLVHRLWL
                     DRPLAPHRPSFLGTGGWGPLDNISVLDRYESEALHWALERRGAVVELHAYAAAAPGADR
                     DAVVPALSRELERQLHLIYPESEAAEVVDSRSLWREDCPLFAPGSFAERPTVRTPDDGL
                     VLAGDGIRIDLPVALMERAATTGTHAANLLLAGFGLPGQELFTVPDYGRLNPLHWFSRP
                     RSEKE"
     gene            complement(9258..10004)
                     /locus_tag="KFLA_RS19170"
                     /old_locus_tag="Kfla_3859"
     CDS             complement(9258..10004)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="KFLA_RS19170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3859"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_012921468.1"
                     /transl_table=11
                     /translation="MSAAQRSDGLPRAEVPAAFDGAAHSYDRLVGANPGYHGQLRLSAA
                     RLRLPGAGAGLRLLDAGCGTGASTAAVLAVAPLAEIVAFDASRQMLAQAEAKGFPTSVR
                     FVHSTVEDLDPAELGGPFDACLAAYLIRNLADPDAGLAKLRGLLKPGARLAIHEYSVAD
                     SRLARAVWNAVCWGIVIPAGRLGSGDAALYRHLRSSVNHFDGARSFQQRLVRAGFTEVS
                     VAPMGGWQRGVAHTFLGTAPSAGEPT"
     gene            complement(10001..10345)
                     /locus_tag="KFLA_RS19175"
                     /old_locus_tag="Kfla_3860"
     CDS             complement(10001..10345)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013862679.1"
                     /locus_tag="KFLA_RS19175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3860"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_012921469.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2.2e-18,
                     bitscore: 65.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLGYTLPAVVAAIAVVVLELRWLRTGLFRRPAYWISMVIVFGF
                     QIPVDGWLTRLDAPIVLYDDNHITGLRFPWDIPVEDFVFGFALVTGALLAWERLGPAAR
                     HHPERDEADR"
     gene            complement(10342..10692)
                     /locus_tag="KFLA_RS19180"
                     /old_locus_tag="Kfla_3861"
     CDS             complement(10342..10692)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013862680.1"
                     /locus_tag="KFLA_RS19180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3861"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_012921470.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.4e-21,
                     bitscore: 75.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRWHYLLVMAACVAITLPLELLGARVYRRPRRWLLALLPVVTIF
                     LVWDAIAIAGGVWGYNPQYLTGWSLPFRIPVEEFVFFVVVPTCGLLTYETVGLMLERIG
                     RYRRTRREQVRP"
     gene            complement(10741..11694)
                     /locus_tag="KFLA_RS19185"
                     /old_locus_tag="Kfla_3862"
     CDS             complement(10741..11694)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="KFLA_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3862"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_012921471.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.2e-116,
                     bitscore: 386.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.1e-61,
                     bitscore: 205.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGELDAAGIKEPRLREAYARCRQLNAEHGKTYFLATRMLAPAQR
                     PAVHALYGFARFADDVVDVPPAGATPADVAASLEQVAQALGHGLDDGRSQDPIIAAVVD
                     CAGRFGIGRDLFDDFLTSMRMDLTVERYPTRADLYRYTRGSAEVIGLQVLPVLGTVTSR
                     AEAAPAAAALGLAFQLTNFLRDVAEDYERGRVYLPLDELAAHGVDDELIGWCVANRRTE
                     PRMTEALRAQIAATRAVYAQARPGIAMLSPISRPCVRTAYVLYSEILDRIEAAGHDVFS
                     RRAHVHGFRKATVAGAALAKGIVARRLYRGSPAGAR"
     gene            complement(11691..13208)
                     /gene="crtI"
                     /locus_tag="KFLA_RS19190"
                     /old_locus_tag="Kfla_3863"
     CDS             complement(11691..13208)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657744.1"
                     /locus_tag="KFLA_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3863"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_012921472.1"
                     /sec_met_domain="DAO (E-value: 1.6e-20, bitscore: 72.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVTGPTDHVVVVGAGFSGLAAALQLAGRGRRVTVVERDDVPGG
                     RAGRRQVDGHHFDTGPSVLTMPELIEETLAAVGASTTGLLRLTELDPAYDARFADGSNL
                     LVHRDADAMAAAIEAFAGPEQAAGFRRLRRWLETLYRVEFDRFIGANFDSPLSMLSPQL
                     AHLVALGGFRRLEPMIGRFITDERLRRVFTFQSLYVGQAPRSALALYGVITYMDTVNGV
                     YFPAGGMSALPDALADAAEKAGVEFHYGATVDHLEGSGRRVSAVRTTDGRRFACDAVVL
                     TTELPTTYRLLGGGPRRVVALQAAPSAVVLHAGLSQRRPELAHHTISFGDAWQSTFHQL
                     IRTGELMKDPSLLITRPTATDPGLAPPGRDTLSILAPVPNLGTGQVRDWDRHGEAYADQ
                     LVELVEQRLAPGLGATISARALITPADWARADMVDGTPFAYAHSFRQTGPFRPGNFPRR
                     TENVVLAGGGTVPGVGVPTALISGRLAADRVTGPVRNRNDRRTGAGR"
     gene            complement(13240..14280)
                     /locus_tag="KFLA_RS19195"
                     /old_locus_tag="Kfla_3864"
     CDS             complement(13240..14280)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="KFLA_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3864"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_202796990.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-43, bitscore:
                     147.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATRALVCTYAAQRCDEHFTVADTGILRAVLTGFVGQGKFVRST
                     FAYLGWLCGRPESDAAARAAASLELLHAFALIQDDVMDDSATRRGSATVHVQLAHWAER
                     QRRPVGAQFGRSAAVLLSDLCLVWAERMLRESGLPAESLAKALPVYDLLRSELAVGQFS
                     DLLNENSAAPSLNAVLDIARRKSGNYTVLRPLELGAVAAGCSPQVLAALRQYGTAIGEA
                     FQLRDDLLGVFGDPLVTGKPLGDDLYQAKATTIVVAAGELAGDTERRELRRLTAGRPLP
                     GVIDERWIQAWQRLIVDTGADELVEKMIAERVEAAVTTLADEPGVPSAPRAALTVLADR
                     CTQRTR"
     misc_feature    complement(14484..14501)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.99"
                     /tool="antismash"
     gene            14542..16020
                     /locus_tag="KFLA_RS19200"
                     /old_locus_tag="Kfla_3865"
     CDS             14542..16020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920407.1"
                     /locus_tag="KFLA_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3865"
                     /product="ubiquinol-cytochrome c reductase cytochrome b
                     subunit"
                     /protein_id="WP_012921474.1"
                     /transl_table=11
                     /translation="MAQPQLPPAAAWLDDRLGIAKLGKKNLRKVFPDHWSFMLGEIALY
                     SFVILILTGVFLALWFTPSMAEVEYQGSYSLLKGLAMSEAYESTLRISFDVRGGLLMRQ
                     IHHWAAVLFVAAMSVHLLRVFFTGAYRKPRELNWLIGIAMLFFGIVEGFIGYSLPDDLL
                     SGTGLRISQGLVQATPVAGSWLAFFIFGGQFPGDDFVARFYTVHVLLLPGIILALVTVH
                     LILVVYHKHTQFPGPGRTEKNVVGYPLLPVYAAKAGGFFFVVFGVLALMGALLQINPVW
                     LYGPYNPAEVTAGSQPDWYMAWLDGAVRLMPGVESEFWGVTISWNIVVPALVMPPLFIG
                     FVALFPFIEQRFTGDRREHHLLDRPRNAPTRTGIGVAIMVFYGILWLNSGNDLIAIHFG
                     LSINAIMWFCRIAVFVGPVLGLVITRRIAISLQRADEQRLEHGLETGVIVRSPDGAYSE
                     KHSPISTYEAYALTAHRQPPAADETTDDLPAKKA"
     gene            complement(16036..16617)
                     /locus_tag="KFLA_RS19205"
                     /old_locus_tag="Kfla_3866"
     CDS             complement(16036..16617)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020387888.1"
                     /locus_tag="KFLA_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3866"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_012921475.1"
                     /transl_table=11
                     /translation="MTAAPTRMSKQARREQLLDAGLGIVRARGTDGLTLVTLAEAAGVS
                     RPIVYDHFGSRTGLLLELYRRLDERHRSALAEALAAADPAAGAVAHVMSTAYFACATDM
                     PEFAAVSAALKGNPEAEAMQHDLLDDYVELMAGAMAPYSSLSVDALKLRCVGVLGAAEA
                     IAAELNHDRATTDDAVTALSDLIVGNLAAG"
     gene            16700..17716
                     /locus_tag="KFLA_RS19210"
                     /old_locus_tag="Kfla_3867"
     CDS             16700..17716
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020387889.1"
                     /locus_tag="KFLA_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3867"
                     /product="saccharopine dehydrogenase"
                     /protein_id="WP_012921476.1"
                     /transl_table=11
                     /translation="METEPVLILGGSGQAGASTGELLRQWHPNLPLTIAGRSLDRAQRV
                     ADELGAANAVTIDLARADLGLPAGHSHSAVVATLWDNHLNGLRYAQDHGVPYVSISNGL
                     VEIAPEVVAGGQRPNTAPILLASHFCAGSVLLATVHLARKFARVDSIRVGALLDEVDAG
                     GPAGLADLERLATASSAGLVRRDGVFTWIPEADARVDVRSIDGTMVPGQQIAVLDVPGL
                     ALATGAADVQLAFAVGESAGRRRGEHPSIEIRIDLDGADETGAPLSTSQYLVHPAGQRP
                     LTALGIALGVERLIGLRGEPVAPGIYTPEALTDPAFAVERLTELGASFVSADTPALK"
     gene            17795..18595
                     /locus_tag="KFLA_RS19215"
                     /old_locus_tag="Kfla_3868"
     CDS             17795..18595
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390644.1"
                     /locus_tag="KFLA_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3868"
                     /product="DUF899 domain-containing protein"
                     /protein_id="WP_012921477.1"
                     /transl_table=11
                     /translation="MTTPENLPKVVSREQWLAARKELLVKEKEVTRLAAAVNAERRRLP
                     MVRIDKPYTFDGPNGRVSLLDLFEGRPQLVMHHFMWTYDIDADGTEHPRDTGCSSCSSA
                     ADQIPARLSQLHARNTSLVAVSRAPYEKIAAFRSRMGWTFPWYSSAGGDFNYDFHATVD
                     DRVAPVQIYLRGEAELAAAGMPFDRTMRGDWPGISAFLRVGDEVFHTYSTFGRGIEQFH
                     NGYPYLDLTALGRQEHWEEPKGRAVPLGRQVGGPGMRLPDEYDV"
     misc_feature    complement(18652..18667)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            18672..19004
                     /locus_tag="KFLA_RS19220"
                     /old_locus_tag="Kfla_3869"
     CDS             18672..19004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020578334.1"
                     /locus_tag="KFLA_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3869"
                     /product="YciI family protein"
                     /protein_id="WP_012921478.1"
                     /transl_table=11
                     /translation="MRYVLLIWHGEEHSEPPEEIGAWPEHQAWLADLETRGLRQGGARL
                     RPAATTKVQVRDGEILVSDGPYAETKDLIGGFVLIDCEHLDEALEVAAGHPFAKFGTVE
                     VRPVWE"
     gene            19001..20218
                     /locus_tag="KFLA_RS19225"
                     /old_locus_tag="Kfla_3870"
     CDS             19001..20218
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020578333.1"
                     /locus_tag="KFLA_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3870"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_041289390.1"
                     /transl_table=11
                     /translation="MSDAVQAAVAEAFAAEWGQVVATLIRVTGDWDLAEDCAADAFAVA
                     LERWRRDGVPRSPGAWLTTTARNRAIDLLRREATGAAKAREAAVLSRAVDAPVEPDEVP
                     DDRLRLIFTCSHPALPFEARIALTLRTLAGLTTAEIARAFLVPEPTMYQRITRAKKKIR
                     EAGIPYRVPPAHLLAQRLNAVLAVIYLLFNEGYTASEGADLVRHNLSAEAIRLGRLLVR
                     LLPEPEAQSLLALMLLHDARRPTRVDAAGGLITLDQQDRSRWDAAKIAEGLRLLPATPG
                     PYQLQAAIAACHTTARSVETTDWPRIVRLYDDLLAIAPSPVVRLNRAVAVAMVEGPAAG
                     LALVDELAASGQLAGYHLLPATRAELLRRQGSYEPAAAAYRDAVELASTDAERDYLRAR
                     LAEIEP"
     misc_feature    19817..19819
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20186..21745)
                     /locus_tag="KFLA_RS19230"
                     /old_locus_tag="Kfla_3871"
     CDS             complement(20186..21745)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="KFLA_RS19230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3871"
                     /product="MFS transporter"
                     /protein_id="WP_012921480.1"
                     /transl_table=11
                     /translation="MTREVVVSMRAGYREWCGLAVLALPCAVVSMDATVLNLAVPELTA
                     DLRPTGAQQLWIVDSYVFVVAGLLMTMGMVGDRIGRRRLLLAGAALFAIASAVAAFAPS
                     PELLIAARVLLGVAGATLMPSTLALIRTMFADPGQRRIALGVWTGSFALGGLAGPLVGG
                     LLLAQYWWGSVFLIALPVMVLLLATATFVLPEFRGGERPRVDLVSAGLSLAAVLAFVSG
                     MKRIAESGPRPEYGVVMAVGVGLAYGFVRRQRRLAHPVIDLALFRSAAFSLPLVVLALT
                     FFVLYGTQFVTAQYLQLVLGLTPLEAGLASLPGTVAYLVTSVSAPLITRRVSTAYGMSG
                     SLLISAIGFGLLTQVQAGGVWIVVIGFVVLSVGLAGVYLQATDLTVSAAPPERAGATSA
                     LVETSADLGGALGIAVLGSIVLAVYRGSLPESRPPGVSAELWTSAHHTLAGITNSPTDD
                     ASRAFLDAARTAFVQGYRLAELVGTIALLLAAATTAITLRRPRTTAVAKVSSGLDLREP
                     GS"
     gene            21829..22341
                     /locus_tag="KFLA_RS19235"
                     /old_locus_tag="Kfla_3872"
     CDS             21829..22341
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023134.4"
                     /locus_tag="KFLA_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3872"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_012921481.1"
                     /transl_table=11
                     /translation="MFIEGLPPATVVAVVNGWGSEPRRAGHRQELPPLPDALLPPWAEA
                     DDAGLEWAADRLFPIFASTDLTERAESLAAVLDRTKVRPTVRYDAEGFASPWLVEPRHA
                     VLAAAALTLRTQFAEHDPARVGLCSAGNCADVYIDVSARAHRRFCSVTCQNRTRTAAYR
                     RRRSATP"
     gene            complement(22327..23460)
                     /locus_tag="KFLA_RS39360"
                     /old_locus_tag="Kfla_3873"
     CDS             complement(22327..23460)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012427.4"
                     /locus_tag="KFLA_RS39360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_3873"
                     /product="glycosyltransferase"
                     /protein_id="WP_012921482.1"
                     /sec_met_domain="MGT (E-value: 2.3e-93, bitscore: 312.2,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTFIGGSGHFRPLVAVARAVEAAGHTVAVAGSGKVTPVVEA
                     AGFVAFPTSGPRVADAPPAAPEPLVAVDPAAEERHFAAAFGRSGARRHAAALLELAGEW
                     RPDVIVRDEADFGSAIAAERLGIPCATVLVLAAGSLVRKELLAEPLGQLRAEYGLPPDP
                     GLAMLDRELVLSPFPPSFRSPDFPLPQTAFSYRTADVVPIAAVRETPTVYFTLGTVFRP
                     DTDDLFSRVLAGLREVPAKVVVTVGERNDPAALGPQPGHVRVERFVPQEELLPYCDLVV
                     SHGGSGSLLGALAHGLPSVLLPLGADQPHNAQRCLELGLGRVLDAVTVGPDEVAATVTE
                     VLADQDHRRAAQRIQTEINGLPDVTRTVALLEASGRR"
ORIGIN
        1 cgacgtcaag ggcaaggggt accagatgaa ggtctgcgac accctcaagc cgtacgtcgg
       61 ctaccagtac ccgaagttcg gcgcgatcgc gaccggcagc aagcacccga acgcggccaa
      121 gctgttcatg cacttcgtgc tcaccgccga aggcatcacc ccggagatgg gctccggcgg
      181 catctccggc aacaaggcgg tgccgcccag ctcgaacaac ccgccggggc tgaccgactg
      241 gagcacccag ctgatgaaat tcgactcggc caagctgctg aaggacttcc aggacgcgca
      301 ggcgatgcag gaccactggc gcctcaacca ccgctgatcc cgtaccgact gccccggagg
      361 aatcgtcccg atggtcatca ccgatgcccg cccaccgaca gtgccgccgc ccgacgccgg
      421 accgccccgc cggcgcgggc ggtggcgcta ccggctgagc gtcgcccggc atgagccgac
      481 cctgctgatc ggcttggtgc tcatcctgct gctgctctac ctggtgatcg cgccgctggt
      541 cgccgtgctg tccgacgcgg tccgggtcca gttcggcgac cagccgaaga ccggtcagca
      601 acctggtgaa ctgaccggct actacctgtg gcgggtcttc cgctcccagg tcagctcgat
      661 cgtgttctgg cagccactgg tgaacacgct ggtcgtcgca gtcggtgtca ccgtgctggc
      721 gctgctgctc ggcgggatct gcgcgttctt gctcacccgc acgaatatcg ccggccgcaa
      781 gtggctgtcc accgcgctgg tggtgccgta catgctgccg tcctggacgt tcgcgctggc
      841 ctggctcgcc ctgttcaaga acgaccgctc gggtggccag gtcggcatcc tggaggcccg
      901 cggggtccag acgccggact ggctggccta cggcgctgtg ccgatcatcg tctgcctcgg
      961 gctgcactac ttcccgttcg tgctgctgct gttcggcaac gcgctgcgcc ggctcgacgc
     1021 gcaactggag gactccgccc ggatcctcgg cgccggtcgg ggcacggtgc tgggccggat
     1081 cacgctgccg ttgatgctgc cgtcgctgtc gtcgtccacg ctgctcgtgt tcggccggat
     1141 cctcggcacc ttcggtacgc cgtacgtcct cgggctgccg gtcgactaca cgctgctctc
     1201 gacgtcgctg ttctccgcgg tccgcaacca cgagcccggc atcaccgcgg tgatcgcgac
     1261 ggtgatcgtg gtgatcggcg tcgcggtcgt cgtcgcggac gcccggctgc tgcgcgagca
     1321 gcgccggttc gtcaccgtcg gcggcaaggg ggcgatggac cggatcatcg agctcggccg
     1381 ctggcggtgg cccgccggtg gcgtggcact gggcgtcttc gcgctcagcg tcgtcgtccc
     1441 ggtggtcacg ctggcgctga ccacggtcac cacgaccccc ggtgttttca gcgcggagaa
     1501 cttcaccctc aagtactggc tggccgagga tctgccgggc gcgcccggct tcccgcacgg
     1561 catcctgcgc ggcaccgaac tgctcgacgc ggcctggaac agcctgcgga tcgtcggtct
     1621 cgcgtcgctc gtgtgtggcg tcgtgggact gctggtcggt tacgtggtgg tccgctcgga
     1681 cggctcgcgg atcgcgtcgg tgctgcgcca ggtcagcttc ctgccctacc tggtgccggg
     1741 catcgcgttc gcggccgcct tcctgtccct gttcgccgta cgccggggtc cggtgccggc
     1801 gttgtacggc tcggtcaccc tgctggtgat cgtgctcgcg gtgacccacc tgccgtacgc
     1861 gtcgaggtcc ggcatcagcg cgatgaccca gctcggccgg gaacccgagg aggccgccca
     1921 ggtcaccggc gccggctggc tcaccagggt ccgggccgtc gtcgtgccga tccagcgcgg
     1981 ctcgctggtc accgggatcg tgctgccgtt catctcgggg atcaaggagc tgagcatcgt
     2041 gatcatgctg accaccaccg ggacgcagct gctcaccacg ctgtcgatca acctgatcga
     2101 cttcgcctac gaccagatgg ccaacgccgt cgtgctggtg atcgcgctcg tcgcgttcct
     2161 ggccacctat ctcacccagc gactgaccag gaccagcctg gcgtccggac tcggaggcta
     2221 gacccgtgcc gaccatcgcc ctgcaatcca tcagcaagtc gtacggcgtg ggcccgctcg
     2281 ccgtgcagga cctcgacctg accattcccg acggctcgtt cacctgtctg ctcggcccgt
     2341 cgggctgcgg caagaccacc acgctgcgga tgatcgccgg actcgagcac cccaccgccg
     2401 gttccatcac ggtcggcggc cgggtgctcg actcggtcga gcagggcacc ttcgtgccga
     2461 ccgagcggcg cggcatgggc ctggtgttcc agaactacgc gctctggccg cacctgacgg
     2521 tgcgccgcaa cgtcgagttc ggcctgcggg tacagaaggt gccggccgcc gaacggcgga
     2581 cccgggtcga cgcggcgctg gcgatgatgc agatcgccac cgtcgccgag cgctacccgt
     2641 cccagctgtc cggcgggcag cagcagcggg tgtctctggc ccggatgctc gcggtcaacc
     2701 cttcggtcct gctgctggac gaaccactct cgaacctgga cgccacgctg cggctggaga
     2761 tgcgggccga gctgaagcgg ctgcacgagg agaccggcca cacgatcgtc ttcgtcaccc
     2821 acgaccagct ggaggcaatg acgatggcga cccaggtcgc ggtgatgaag gacggcgtcc
     2881 tgcagcagct cgctcccccg atggacgtgt accaccgccc ggccaacgtg ttcgtcgccg
     2941 ccttcgtcgg cagtccgccg atgaacctcg cgccctgcga tgcggagggc gacggcctcg
     3001 gcggtcttgc ccgccagtac ctgcaactgg cccaggtcgg gccggtcgac cgggtcgcca
     3061 cggtcggcgt ccgccccgag gcggtccgcg tcgtcgatgc cggccacccc ggcagtgagc
     3121 gggagttggc gttcgacggc caggtccggg cggtgctgcc gaccggggcg gcctggacgg
     3181 tctcgctgac ggtcgggtcc accgagctgt acctggtctc caccgacgaa gtcgacgcga
     3241 ccacgggcaa cacgatccgc tgcgcggtgc aacgcaaggc cctgcatgtc ttcggccctg
     3301 acggcgaccg cctcaacctg ggcagtggcc gggacgccga gcgcgaggag gtggcccagt
     3361 gggtcagctg atcacgcccg aggccctgct gctcgacttc ggtggcgtgc tggtcgcgac
     3421 caccgggcgc ccgggctggg ccggcgagct ggctgccgag ctgtccgacc agctgagccg
     3481 cgccggcacc ccggagctga ccgtcgacga gatccgcacc gacctggagg ccggcgccgc
     3541 cgcggactcg tactggaaga acgcgatgtc ccggccgccc acaccccgcg agctgaccca
     3601 tcgggagttc tggaccgact tcgtcgccgc cgactggcca cccggtccgc gggcctgggt
     3661 gaccgcgcac gcctcggtgc tctgccggcg gatgggcgaa ctgcgccagc accgggccca
     3721 ccgcgagggc atcccggaac tgctggacac cgcggccgcc gccggcatcc cggtcggggt
     3781 cgtgagcaac gcgctcagcg gggccgtgca ccgcgactac ctggagcgga ccgggctggt
     3841 gaagcagctc gcggtgcaga tctacagcga cgagatgggg atccggaaac cccatcccga
     3901 gctgatcctg ctcgccgccc gcgcgctcgg cgtaccggtc ggccggacct ggtacgtcgg
     3961 ggacaacttc gaccgcgacg tgctctgcgc ccggcgggcc ggcgccggcg cggccgtcct
     4021 gatggaggcc ccgggcacct atcagcgccc gtacgccgtg cgggcggtgc ccgacgcgat
     4081 cgtcccggac cccgtcgccc ttcgcacgct gctgctcgaa gccctctgac cactactgcc
     4141 cagggagtcc gatgacgacc acaccaggta ctgacgcacg ccccgatccg gagctcacgg
     4201 cgtcctcgcg cgagctgcgg gagctggccg gccaggccgt ccggctggtc gccgacgacc
     4261 tgcgcgccgc ctttcgcggt gccatcgccg tgcagtacaa acgcgaccgg cacgacccgg
     4321 tcaccgagca cgaccggcgg gccgagaagg cgatcgccga gctgctcacc ggtcgcgccc
     4381 cgggcagcac cgtcgtcggc gaggaggacg gaacgtcggc cgggaacggc gcggtcacct
     4441 ggtacgtcga cccgatcgac ggtacggcga acttcgccca cggactcgcc ttcttctgca
     4501 cctcgatcgg cgcggtcgtg cacggccgga tcgtggccgg tgcggttctc gacccggtcg
     4561 cggaccacct gttcaccgcc gacctgacgg gcgcgtggct caacggccgg ccactgcgct
     4621 cccgcggggt catcgaggag gcgcaggctc tgctgatcac cagctacccg aacgcgcgcg
     4681 cactcgagtc cgacggcacc gaaggtctgg cctggttcgg ggagctcgtt gccggctacg
     4741 gcacggtccg gcgcccgggc agtgcggccc tcagcctgtg ccacgtcgcc gccggctggg
     4801 ccgacgccgc cctcgggacg tcggtcagcg cctgggacat ctgcgccgcc cggctgatcg
     4861 tcgagcagtc cggcggccgg taccacggct tcggcggatc gggctgggac cagccgggct
     4921 acgccgcgca caccgccgac ctggaaccga cggtgctgcg cggattcgtc gacgccttcc
     4981 cggcgcgtcc ggacggcgag gcccaggcat gacgccgcag ctgcgctacc cgtggctggt
     5041 gaccgatctc gacggcaccc tggtcgaccg ggacctggag atcccggccc gcaacctgga
     5101 ggcagtggac cggtaccgcg cggccggcgg cacggtcacg atcgcgaccg ggcgcaacga
     5161 gcgatcggcc ggccggtacc acgcccagct cggtctggac accccgctga tcctctacaa
     5221 cggcgcccgg atcgtggatc tcgcctcggg ccggcgtctg ctggatctga ccctgggcga
     5281 ggcgtggccg ctggtcgcgg cccgagcgct gccccggctg ccgagcgcgg tcggcgccgt
     5341 cggcttccac gacctcgacg cctacgtgct caagccggcg ccggccctga cccagtacgc
     5401 cggccgcgac cagatccagc tggtcgaaac cgcaccgccg gggtccccca ccaagctgat
     5461 gctgatcgcc gagtcaccgg gtgagctgga tcaggtcgcc gagctgatcg cgtcggtgac
     5521 catcgccgtg cgactggtca ggtccgagaa gacctacctg gagatcctgc ccgcgaacgc
     5581 cgacaagggc agcgcactgc gggcgctggt ggcgtcggcc ggcgtgtccc tggaccaggt
     5641 tgccgcggtc ggcgacaacc ccaacgacct ggagctcatc cagaccgcgg gtctcggtgc
     5701 ggccgtggcc gacggccatg cggaggtggt ccggaccgcc gacgtcgtcg tcgccgcgtg
     5761 ctccgacgcg gccgtcgccg acctgattga ccgctacctt ctgtgctgac gacccggctc
     5821 agtggcggaa gccggtttcg gcgtcgcgga tcagttcgtg ggccgcgtcg acgacgtccc
     5881 ggtcggactg gtgggcgcac tgccggagca tgccgagcgc tcggtcggcg ccgatcgagt
     5941 agcgctccat cagcaggccg accgcctcgc cgatcaggtc gcgggtctcg acggcggtca
     6001 gcagctgttc ggtccgctgg gcccaggcgt acgcgaccgc cgcctggatg gccagcgctt
     6061 ggccggcctg ctcgtcctcg gcggtgaagc cgtcggggtc gagcgtgtac agattgagga
     6121 caccgagcgt gcggtcgtcg acgtacagcg ggaggcacag cacgccggtg acgcccagct
     6181 ccagcaccgg tacggcgaaa cgcggccagc gctcgtcatc ggcgagccgg gcggcccgga
     6241 cggtctggcg ggaagccaac gcgtccagcg acgggccctc cccgaggtcc gtcagcaccg
     6301 cgccgatccg catcgccagc tcgctcgacg cggccttgac gtcgacgcgc tcggggccgg
     6361 ccggaagggt caccgagccg gcgacgacgg gcggtagcag ctcgatcgcc ccgcgcaccg
     6421 cctccttcag gacggcgtcg ggctcctcgg tctcctgcag cgtgcgggcg agcttgccca
     6481 ggtcagcggc gaactccgtc gaaccggccg tcggccggtg cggcggtcga tccgaccgtt
     6541 gccgctgctg cgggatctcc accgaaatgc ccccaaccct ttcctcctgc ctaccacccc
     6601 cggccggtac cgtccaggca agcggcgcgc cctcttctcc gggctcggcc ggggcgcccg
     6661 gcggtcagcg gccgcgggtg cggaggtggt agcggcgttc ggcgtaggcc aggtcgtcgc
     6721 gccacagccg gcccgcggcc cagcgcatcg ccggccgcag cgcgggcgcc gcgtgccggg
     6781 cgaccgcgaa gcccggccgg tccgacgcgg cgacggtcgc ctcgatcacc gccgttctcg
     6841 ggcgcccgtc gggacccggg cccagcgggg tggcgtgagt ctcgacgaca ctgccggcgc
     6901 cctcgccctc ggcgatgcgc atcaccacgg tgcgaggtcc ggggcaggtg aactcggccc
     6961 ggaccggaac gccgatcggt ccacccagcc ggaaggtgac gtcgacgacg aacttgtcgt
     7021 cgcccgcgtc gtcaccgccc tgaggcagct cgcgcacccg caggtcggag aacgagtacg
     7081 ggtggaacca ggcgccgtgc cacgggtcca gccggttcgc gacgatgtcg atcggttcgc
     7141 actgccccga catcgtggcc accgcgtcga ggcaggcacc cgcaggccgc tccggcacca
     7201 gcggcaggtc ggtcggctcc tctcccccga cacggtcgag ccgcacccag cacagcacgc
     7261 cgtcgtcgtg gctgggatag gccagccagc cggtccggtc gtcgtcgtca ccgacgctca
     7321 ggccgtgcca gcggcagacc actcgcccgc actcgacctt gcccagcgcg agcggcgcac
     7381 ccaagtgggg gcaggctcct ggcccgaccc gcagtgttcc gtccggacac cgccaggcga
     7441 ccagctcggt accaccgacc tccgcgccga acggcgtctt cgtgccgacg tcccggctgg
     7501 cggcgaacac gaaccagttg cccgaaggcc gcacggacgc ccgcttgacc gccgcctcga
     7561 tcagcgccgg cgaggcgtcg cggtacgtcg gctgctgccg cgcccagggt tgtctcggca
     7621 gccactggag cggccagcgg tccggccacc ggcgcccgat cgctgtggac acctcgtgtg
     7681 tcctgcccat acctactcct tctccgatcg aggtcgtgag aaccagtgca gcgggttgag
     7741 ccggccgtag tccgggacgg tgaacagctc ctgcccgggc aggccgaacc cggcgagcag
     7801 caggttcgcc gcgtgcgtgc cggtcgtcgc cgcccgttcc atcaacgcga ccggcagatc
     7861 gatccggatg ccgtcgccgg ccaggaccag cccgtcgtcc ggcgtacgga ccgtggggcg
     7921 ttcggcgaag ctgcccgggg cgaacagcgg gcagtcctcg cgccacagcg accgcgagtc
     7981 caccacctcg gccgcctccg actccgggta gatcaggtgc agctgccgct ccagctcacg
     8041 gctcaaggcg ggcacgaccg catcccggtc ggcgccggga gccgcggccg cgtacgcgtg
     8101 cagctcgacg accgctcccc gacgctccag cgcccagtgc agcgcctcgg actcgtagcg
     8161 gtcgagaacg gagatgttgt ccagcggccc ccacccgcct gtccccagga acgacggccg
     8221 gtgcggtgcc agcggccgat ccagccacag ccggtgcacc aggaacggcg gggccgtcct
     8281 cagccgggcg acgttctccc gccagccggg atcgcccagc tcgggcgacg cctggacgac
     8341 gtcccgcagc gcccggggat cggtggccag cacgaccccg tcggcatcga cggcgccgtc
     8401 gccggtgtgc acgcggtact tccgttcccc gccgggctcg acggtgtgca cggaagtacc
     8461 ggtccgcacg tccaccccca gctccgcgag gtggccgccc agcggatccc acaggctgat
     8521 cgcgaacgtg tccgtcggta cgtcgaacag cagtccttcc gacgagccga ggaagtacag
     8581 gtggaacatc accgcgagct cggccgcgga cagctccttc ggcgacgcga agaagctgcg
     8641 ggagaacacc tcgaacgcca ggtgccgcgc cgcgggcggg aagttgatcg cgtcgagcag
     8701 ttcctccgcg gtggtgccgt ccagctgctc gtagatccgg ggcacccgga cggttgccag
     8761 cggcaacgct gcgcgggcgt tcagccggag caggtccggg accgagaagg tcgggctctt
     8821 caccgcgaag gcgagcgcgt tccacggcgg ccggcgcgga atgccgcgga acgtgtcggt
     8881 gcgtccctcc ggatccatca acgggtagtc ggcgaccggc gtgagccgct ccagcgccgg
     8941 gtcggtgcgc gcgagcagcc gacgcaggtt gtagtactgc cggaagaacg cgtggaagcc
     9001 gcggctcatc gtgacggtcg aaccgtcgcc gagctggtcc ggccaggcgc ccacccggcc
     9061 accgaggtac ggctctcgct ccaccaggac gacgccgact ccgcgctcgg ccagcactgt
     9121 cgccgcggac agcccggcga tgccgccgcc gacgaccacg acgcggggtt ggcgcgcgcc
     9181 gcgaggacca gtggccgcag gcaccgggtg ccggacgatc cgccggtcgg agccggccca
     9241 cggaggccgg ccgccggtca cgtcggctcc ccggccgagg gtgcggtgcc caggaaggtg
     9301 tgcgcgactc cgcgctgcca accgcccatc ggggccacgg agacctcggt gaagccggcc
     9361 cggacgagtc gctgctggaa gctccgcgcg ccgtcgaagt ggttcacgct gctgcgcagg
     9421 tgacggtaga gcgccgcgtc gccgctgccg agtctcccgg cggggatgac gatgccccag
     9481 cacacggcgt tccacaccgc ccgggcgagg cgcgaatcgg ccacggagta ctcgtggatc
     9541 gccagccgtg cacccggctt cagcagtccc cgcagcttcg ccagcccggc gtcgggatcg
     9601 gcgaggttgc ggatcaggta cgccgccagg caggcgtcga aggggccgcc gagctcggcc
     9661 gggtcgaggt cctcgaccgt gctgtgcacg aaccgcaccg acgtcgggaa tcccttggcc
     9721 tcggcctggg cgagcatctg ccgcgaggcg tcgaaggcga cgatctcggc cagcggcgcc
     9781 accgccagca ccgcggccgt cgaggcgccg gtcccgcagc cggcgtccag gagtcgcagg
     9841 ccggcgcccg ctccggggag ccggaggcgc gcggcggaca gccggagctg gccgtggtag
     9901 cccgggttcg cgccgaccag ccggtcgtaa ctgtgggccg cgccgtcgaa ggccgcaggg
     9961 acctccgcgc gcggcagtcc gtccgaacgc tgcgctgcac tcatcggtcg gcctcatctc
    10021 gttcggggtg gtgacgggcg gcgggtccga gccgctccca ggcgagcagg gcgccggtga
    10081 cgagcgcgaa gccgaacacg aagtcctcga ccgggatgtc ccaagggaac cgcaggccgg
    10141 tgatgtggtt gtcgtcgtac agcacgatcg gggcgtccag ccgggtcagc cagccgtcga
    10201 ccgggatctg gaagccgaag acgatcacca tgctgatcca gtacgccgga cgccggaaca
    10261 ggccggtccg cagccagcgc agttccagca cgaccaccgc gatcgccgcg acgaccgccg
    10321 gcagggtgta gccgagacct ctcatggccg cacctgctca cgccgcgtcc ggcggtaccg
    10381 gccgatgcgt tcgagcatga ggccgaccgt ctcgtaggtg agcagcccac aggtcggcac
    10441 cacgacgaag aacacgaact cctcgaccgg gatccggaac ggcaggctcc agccggtcag
    10501 gtactgcggg ttgtagcccc agacgccgcc ggcgatcgcg atcgcgtccc agaccaggaa
    10561 gatcgtcacg accggcagca gcgcgagcag ccaccgccgc ggccgtcggt agacccgggc
    10621 gccgagcagc tccagcggca gcgtgatcgc gacacaggcc gccatcacca gcaagtagtg
    10681 ccagcggtcc acagcgctcc tcccttccgg ccggtccggt gcgggagacg cagcgtgttg
    10741 tcatcgtgca ccggctggac tcccccggta cagccggcgc gcgacgatgc ccttcgccag
    10801 tgccgctccg gccacggtcg ccttgcggaa gccgtgcacg tgcgcgcgcc gggagaacac
    10861 gtcgtgaccg gccgcctcga tccggtccag gatctccgag tacagcacgt acgccgttcg
    10921 cacgcacggc cgggagatcg gcgacagcat cgcgatgccc ggccgggcct gcgcgtagac
    10981 cgcccgggtc gccgcgatct gcgcccgcaa cgcctcggtc atccgcggct ccgtccgccg
    11041 gttggcgacg caccagccga tcagctcgtc gtcgaccccg tgggcggcga gctcgtcgag
    11101 cggcaggtag acccggccgc gctcgtagtc ctcggcgacg tcgcgcagga agttcgtcag
    11161 ctggaaggcc aggccgagcg cggcggcggc cggtgcggcc tcggcgcggg acgtcaccgt
    11221 gccgagcacc ggcagcacct gcaggccgat cacctcggcc gacccgcggg tgtagcggta
    11281 caggtcggcc cgagtcgggt accgctcgac ggtgaggtcc atccgcatcg aggtcaggaa
    11341 gtcgtcgaac aggtcgcggc cgatgccgaa ccgcccggcg cagtcgacca ccgcggcgat
    11401 gatcgggtcc tggctgcggc cgtcgtcgag gccatggccg agcgcctgcg ccacctgctc
    11461 cagggaggcc gccacgtcgg ccggggtcgc gccggccggc ggcacgtcga cgacgtcgtc
    11521 ggcgaacctg gcgaacccgt acagtgcgtg cacagccggg cgctgggccg gcgccagcat
    11581 ccgcgtcgcc aggaagtagg tcttgccgtg ctcggcgttc agctgccggc aacgcgcgta
    11641 cgcttcccgc agccgcggct ctttgatgcc cgcggcatcg agctccccag tcatcgtccg
    11701 gctcccgtcc tgcggtcgtt gcggttgcgc accggaccgg tgacccggtc ggccgccagc
    11761 cgtcccgaga tcagtgcggt cggtacgccg accccgggga ccgtgcctcc gccggccagc
    11821 acgacgttct cggtccgccg cgggaagttg cccggccgga acggcccggt ctggcggaag
    11881 gagtgcgcgt aggcgaacgg cgtaccgtcg accatgtccg cgcgggccca gtccgccggg
    11941 gtgatcaggg cccgcgccga gatcgttgcc cccagccccg gtgcgaggcg ttgctcgacc
    12001 agctccacca actggtcggc gtacgcctcg ccgtggcggt cccagtcgcg gacctgcccg
    12061 gtgccgaggt tcggcaccgg cgcgaggatc gacagggtgt cgcggccggg cggcgcgagg
    12121 cccggatcgg tcgcggtcgg gcgggtgatc agcagcgacg ggtccttcat cagctcgccg
    12181 gtccggatca gctggtggaa cgtcgactgc cacgcgtcgc cgaacgagat cgtgtggtgc
    12241 gccagctccg ggcgccgctg cgacagcccc gcgtgcagca cgacggccga gggcgccgcc
    12301 tgcaacgcaa cgacgcgacg gggtccgccg ccgagcagcc ggtacgtggt cggcagttcg
    12361 gtcgtgagca cgaccgcgtc gcaggcgaac cgccggccgt cggtcgtgcg gaccgcgctg
    12421 acccggcgcc ccgacccctc caggtggtcc acggtcgcgc cgtagtggaa ctcgacgccg
    12481 gccttctccg cggcgtcggc cagcgcgtcg ggcagcgcgc tcatcccgcc ggccgggaag
    12541 tacacgccgt tgaccgtgtc catgtaggtg atgacgccgt agagcgcgag cgccgaccgc
    12601 ggcgcctgcc cgacgtagag ggactggaag gtgaacaccc ggcgcagccg ctcgtcggtg
    12661 atgaaccggc cgatcatcgg ctccagccgg cggaagccgc cgagcgccac caggtgggcc
    12721 agctgcggcg agagcatcga cagcggggag tcgaagttgg cgccgatgaa gcggtcgaac
    12781 tccacccggt acagcgtctc cagccagcgc cgcagccggc ggaacccggc cgcctgctcg
    12841 ggcccagcga aggcttcgat cgcggccgcc atcgcgtcgg cgtcccggtg caccagcagg
    12901 ttgctgccgt cggcgaagcg cgcgtcgtac gccggatcca gctcggtgag gcgcagcagc
    12961 cccgtcgtac tggcaccgac cgcggccagc gtctcctcga tcagctcggg catggtcagc
    13021 acgctgggac cggtgtcgaa gtggtgcccg tcgacctgcc gccgaccggc tcggccgccc
    13081 ggtacgtcat cgcgctccac gacggtgacc cgacgcccgc ggccggccag ctgcagggcg
    13141 gcggcgagcc cggagaatcc cgcgccgacc acgacgacgt gatcggtcgg cccggtcacg
    13201 cgacgcatca ccggagcctc cgcggggcag ctgccggcgt catcgcgtcc gctgcgtgca
    13261 tcggtcggcc aggacggtca gcgcggcccg gggagccgac ggcacgccgg gttcgtcagc
    13321 gagcgtcgtc accgcggcct cgacgcgttc ggcgatcatc ttctcgacca gctcgtcggc
    13381 gccggtgtcg acgatgaggc gctgccacgc ctggatccag cgctcatcga tcacgcccgg
    13441 cagcgggcgc ccggcggtca gccgccgcaa ctcccggcgc tcggtgtcgc cggcgagctc
    13501 accggccgcg accacgatcg tggtcgcctt cgcctggtac aggtcgtcgc ccagcggctt
    13561 cccggtcacc agcggatcac cgaagacgcc gagcaggtcg tcccgcagct ggaacgcctc
    13621 gccgatcgcc gtcccgtact gccgtagcgc ggccagcacc tgcggggagc agccggccgc
    13681 gacagcgccg agctccagcg gccgcagaac ggtgtaattg cccgacttgc ggcgggcgat
    13741 gtccagcacc gcgttgaggg agggcgcagc gctgttctcg ttgagcaggt cgctgaactg
    13801 tccgacagcc agttcgctgc gcagcaggtc gtagaccgga agtgccttgg ccagcgactc
    13861 ggccggcagg cccgactccc gcagcatccg ctcggcccac accaggcaca ggtcactcag
    13921 cagcacggcc gccgaccgcc cgaactgcgc accgacgggc cgccgctgac gctcggccca
    13981 gtgcgccagc tggacgtgaa ccgtggcact tccccttcgc gtcgctgagt cgtccatcac
    14041 gtcgtcctgg atcagcgcga aggcgtgcag cagctccaaa ctggcagcgg cacgggccgc
    14101 ggcgtcggac tcgggccggc cgcagagcca cccgaggtag gcgaacgtcg agcggacgaa
    14161 cttgccctgg ccgacgaacc cggtcagcac ggcacgcagg atgccggtgt cggcgacggt
    14221 gaagtgctcg tcgcaccgct gcgcggcgta cgtgcagacc agcgcgcgag tggcgcccac
    14281 gcgggactcc agccagcggt caggcgcggt gggagcgtgc catggtgcga cctggtcaac
    14341 caaggtgggt cctccaacgt ccgggtcagg gccgccgacg ggcccgtcgc ggtcgaagtg
    14401 cccgccggtt cccctgcgac cggccggcca aaccgaacct gtgcggcggg gcccgtggcg
    14461 tccggctcag actagcggcg tgcataactt tcgcctaact tctgccgtag cctggcaggg
    14521 acggaaacga ggtgacaggc gatggcacaa ccccagctcc ccccggcggc ggcctggctg
    14581 gacgaccggc tcggcatcgc gaagctcggc aagaagaacc tgcgcaaggt cttcccggac
    14641 cactggtcgt tcatgctggg cgagatcgcg ctctacagct tcgtcatcct gatcctcacc
    14701 ggggtcttcc tggcgctgtg gttcacgccg tcgatggccg aggtcgagta ccagggctcg
    14761 tacagcctgc tcaagggtct ggcgatgtcg gaggcgtacg agtccacgct gaggatctcg
    14821 ttcgacgtgc gcggcggtct gctgatgcgg cagatccacc actgggccgc cgtgctgttc
    14881 gtcgcggcga tgagcgtgca cctgctgcgg gtcttcttca ccggcgccta ccgcaagccg
    14941 cgggagctga actggctgat cgggatcgcg atgctgttct tcggcatcgt cgagggcttc
    15001 atcggctaca gcctgcccga cgacctgctc tccggcaccg gcctgcggat ctcccagggc
    15061 ctggtccagg ccaccccggt ggccggcagc tggctggcgt tcttcatctt cggcggccag
    15121 ttccccggtg acgacttcgt cgcccggttc tacaccgtgc acgtgctgct gctgcccggc
    15181 atcattctcg ccctggtcac cgtgcacctg atcctggtcg tctaccacaa gcacacccag
    15241 ttccccggcc ccggccggac cgagaagaac gtggtcggct acccgctgct gccggtgtac
    15301 gccgcgaagg ccggcggctt cttcttcgtc gtgttcgggg tgctggcgct gatgggcgcc
    15361 ctgctgcaga tcaacccggt ctggctgtac ggcccgtaca acccggccga ggtgaccgcc
    15421 ggctcccagc ccgactggta catggcgtgg ctcgatggcg cggtccggct gatgccgggc
    15481 gtcgagtcgg agttctgggg cgtcacgatc agctggaaca tcgtcgtacc ggcactggtg
    15541 atgccgccgc tgttcatcgg gttcgtcgcg ctgttcccgt tcatcgagca gcgcttcacc
    15601 ggcgaccggc gcgagcacca cctgctcgac cggccgcgca acgcgccgac ccggaccggc
    15661 atcggcgtgg cgatcatggt cttctacggc atcctctggc tgaacagcgg caacgacctg
    15721 atcgccatcc acttcggcct gtcgatcaac gcgatcatgt ggttctgccg gatcgcggtc
    15781 ttcgtcgggc ccgtgctcgg cctcgtcatc acccgccgga tcgcgatctc gctgcaacgc
    15841 gccgacgagc agcggctcga gcacggcctg gagaccggcg tcatcgtgcg ctcgcccgac
    15901 ggcgcgtact ccgagaagca cagcccgatc tcgacgtacg aggcgtacgc cctcaccgcc
    15961 caccggcagc cgccggcggc ggacgagacc accgacgacc tgccggcgaa gaaggcctga
    16021 ccgcctggcg cccggttatc cggccgccag gtttccgacg atcaggtcgc tcaaagccgt
    16081 gacggcgtcg tccgtggtcg cgcggtcatg gttgagttcg gcggcgatcg cctcggccgc
    16141 gccgaggacg ccgacgcagc gcagcttcag cgcgtccacc gacaggctcg agtacggcgc
    16201 cattgcaccg gccatcaact cgacgtagtc gtcgagcagg tcgtgctgca tcgcctcggc
    16261 ctccggattg cccttcagcg cggcggagac ggccgcgaac tccggcatgt cggtcgcgca
    16321 cgcgaagtac gccgtactca tcacgtgggc caccgcgccg gcggctggat cggccgccgc
    16381 gagcgcctcg gccaaggcgg atcgatgccg ctcgtcgagt cgccggtaga gctccagcag
    16441 caggccggtg cgactgccga agtggtcgta cacgatcggc ctgctcactc cggccgcctc
    16501 ggcgagcgtg accagtgtga ggccgtcggt tccccgggcg cgaacgatgc ccaggccggc
    16561 gtcgagcaac tgctcgcgcc tggcctgctt ggacatccgg gtcggtgctg ccgtcatgga
    16621 tcctccttgc gttccggggt cagcctaggc tacaaagtgt aggttacaaa atgtagcttt
    16681 cgctgatcga gaggacacca tggagacgga acctgtactc atcctgggcg gttcgggcca
    16741 ggcgggcgcg agcaccggcg agctgctgcg gcagtggcac ccgaacctgc cgctgacgat
    16801 cgcgggccgg agcctcgacc gcgcgcagcg ggtggccgac gagctgggcg ccgcgaacgc
    16861 ggtcacgatc gacctggccc gcgccgatct cggcctgcct gcgggtcaca gccactccgc
    16921 ggtggtggcc acactctggg acaaccacct gaacgggttg cggtacgcgc aggaccacgg
    16981 tgtgccgtac gtcagcatct ccaacggtct ggtggagatc gcaccggagg ttgtcgcggg
    17041 cggccagcga ccgaacacgg cgcccatcct gctggccagc cacttctgcg cgggctccgt
    17101 cctgctcgcc acggtgcacc tggcccggaa gttcgcccgg gtcgactcga tccgggtcgg
    17161 cgccctgctg gacgaggtcg acgccggcgg accggccggg ctggccgacc tggagcgcct
    17221 ggcgacagcc tcctcggcag gactcgtccg ccgggacggg gtcttcacct ggatccccga
    17281 ggccgacgcg cgggtcgacg tgcgcagcat cgacggcacg atggtgcccg ggcagcagat
    17341 cgccgtgctc gacgtgccag gtctcgcgct cgcaacgggc gcggccgacg tccagctggc
    17401 gttcgccgtc ggtgagtccg ccggccggcg acgtggcgag cacccgtcga tcgagatccg
    17461 catcgacctc gacggggccg acgaaaccgg cgcgccgctc agcaccagcc agtacctggt
    17521 ccacccggcc ggccagcggc cgctgaccgc gctcggcatc gcactcgggg tggaacggct
    17581 gatcggtctg cgtggcgagc ccgtcgcccc gggcatctac acccccgagg cgctgaccga
    17641 cccggccttc gcggtcgagc ggctgacgga gctcggcgcg agcttcgtca gcgcggacac
    17701 gcccgcgctg aaatagctgt ggcggggttg tcgaatccgg gacggccccg ttcgtcggtg
    17761 gggcacaacc gaccccggag aacggagtac agcgatgaca accccggaga acctgccgaa
    17821 ggtggtgtcg cgggagcagt ggctggccgc gcgcaaagag ctgctggtca aggagaagga
    17881 ggtcacccgg ctggcggccg ccgtcaacgc cgagcggcgg cggctgccga tggtgcgcat
    17941 cgacaagccg tacaccttcg acgggccgaa cgggcgggtc agcctgctcg acctgttcga
    18001 agggcggccg cagctggtca tgcaccactt catgtggacc tacgacatcg atgccgacgg
    18061 caccgagcac ccccgcgaca ccggctgctc cagctgctcg tcggccgccg accagattcc
    18121 ggccaggctg agtcagctgc acgcccggaa cacctcgctg gtggcggtga gccgggcgcc
    18181 gtacgagaag atcgccgcgt tccgctcccg gatgggctgg acctttccgt ggtactcctc
    18241 ggccggcggc gacttcaact acgacttcca cgccaccgtg gacgaccggg tcgcaccggt
    18301 gcagatctac ctgcgcggcg aagcggagct ggccgccgcc ggcatgccgt tcgaccggac
    18361 catgcgcggg gactggccgg gcatcagcgc gttcctgcgg gtcggcgacg aggtgttcca
    18421 cacctactcg acgttcggcc gcggcatcga gcagttccac aacggttatc cctacctgga
    18481 tctcaccgcc ctcggccggc aggagcactg ggaggagccg aagggacgcg cggtgccgct
    18541 cggccggcag gtcggcgggc cggggatgcg cctgcccgac gagtacgacg tctgatcccc
    18601 ggcgcggccc gacgaccgtg gcacagtggt ggtcgcgtca ccggaagagg tgtgaaagag
    18661 gtgcgagcac gatgaggtac gtgctgctga tctggcacgg cgaggagcac tcggaaccgc
    18721 cggaggaaat cggcgcctgg ccggagcacc aggcctggct cgccgacctg gagacgcgcg
    18781 gcctgcgcca gggcggcgcc aggctgcgcc ccgccgccac gacgaaggtg caggtgcgcg
    18841 acggcgagat cctggtctcc gacggcccgt acgccgagac caaggacctg atcggcggct
    18901 tcgtgctgat cgactgcgag cacctcgacg aggcgctcga ggtcgccgcc gggcacccgt
    18961 tcgccaagtt cggcaccgtc gaggtccggc cggtgtggga gtgagcgacg ccgtccaggc
    19021 ggcggtcgcc gaggcgttcg ccgcagagtg gggtcaggtc gtcgcgacgc tgatccgggt
    19081 gaccggggac tgggacctgg ccgaggactg cgcggcggac gcgttcgcgg tggcgctgga
    19141 gcggtggcgg cgcgacggcg taccgcgcag cccgggtgca tggctgacca ccacggcccg
    19201 gaaccgggcg atcgacctgc tccgcaggga ggcgaccggg gcggcgaagg cccgcgaggc
    19261 ggccgtgctc agccgggccg tcgacgcacc ggtcgagccc gacgaggtgc cggacgaccg
    19321 gctgcggctg atcttcacct gctcccaccc ggcgctgccg ttcgaggcgc ggatcgcgct
    19381 gacgctgcgc acgctggccg ggctgacgac cgcggagatc gcgcgggcgt tcctggtgcc
    19441 ggaaccgacc atgtaccagc gcatcacccg ggcgaagaag aagatccgcg aagccggcat
    19501 tccgtaccgc gtaccgccgg cgcacctgct ggcccagcgg ctgaacgctg tgctcgcggt
    19561 gatttacctg ctgttcaacg agggctacac ggccagcgag ggcgcagacc tggtgcggca
    19621 caatctcagc gccgaggcga tccggctggg ccggctgctc gtccggctgc tgcccgaacc
    19681 ggaggcgcag agcctgctcg cgctgatgct gctgcacgac gcgcggcggc cgacccgggt
    19741 cgatgcggcg ggcgggttga tcaccctcga ccagcaggac cgctcgcgct gggacgcggc
    19801 caagatcgcc gagggcttac ggctgctgcc ggcgacacct ggcccgtacc agctccaggc
    19861 ggcgatcgcg gcctgccaca ccacagcgcg gagcgtggag acaactgact ggccgcggat
    19921 cgtgcgcctc tacgacgacc tgctcgcgat cgccccgtcg ccggtcgtcc gcctcaaccg
    19981 cgcggtcgct gtcgcgatgg tcgagggccc ggcagcggga ctcgcgctgg tcgacgaact
    20041 ggcggcgtcc ggccagctcg ccggctacca cctcctaccg gccacccgcg ccgagctgct
    20101 ccgcaggcaa ggctcgtacg aacccgcagc cgcggcgtac cgggacgctg tggaactggc
    20161 atccaccgac gcggagcggg actacctaag agcccggctc gcggagatcg agccctgaac
    20221 tcacctttgc cacggctgtt gtccgggggc ggcggagggt gatcgcggtg gtggcggcgg
    20281 ccaggagcag ggcgatggtg ccgacgagtt cggcgaggcg gtagccctgg acgaaggcgg
    20341 tgcgggccgc gtccaggaag gcgcgggacg cgtcgtcggt cggcgagttc gtgattccgg
    20401 cgagggtgtg gtgggcgctg gtccacagct cggcggagac gcccggcggc cgggactccg
    20461 gcaaggagcc gcggtagacc gcgagcacga tgctgccgag aacggcgata cccagcgcgc
    20521 cgccgaggtc cgcgctggtc tccaccagcg cggaggtcgc accggcgcgt tccggtggcg
    20581 cggcggagac ggtcaggtcg gtggcctgga ggtacacgcc ggccagaccg acggagagca
    20641 cgacgaatcc gatcaccacg atccacaccc cgcccgcctg tacctgcgtc agcaggccga
    20701 agccgatcgc gctgatcagc agactgcccg acatcccgta cgccgtactg acgcgccggg
    20761 tgatcaacgg cgccgacacc gaggtgacca gataggcgac cgtgcccggc agcgacgcca
    20821 acccggcctc cagcggcgtc agcccgagca ccagctgcag gtactgcgcg gtgacgaact
    20881 gcgtgccgta gagcacgaag aatgtcaacg ccagcacgac cagcggcaga ctgaacgcag
    20941 ccgagcggaa cagcgccaag tcgatcaccg gatgcgccaa ccgtcgttgc cggcggacga
    21001 acccgtacgc cagcccgacg cccacggcca tcaccacgcc gtactccggc cgcgggccgc
    21061 tctccgcgat ccgcttcatc ccggacacga acgccagcac cgcggccagc gacagcccgg
    21121 cgctgaccag atcgacgcgc gggcgctcac caccccggaa ctccggaagc acgaacgtcg
    21181 ccgtcgcgag cagcagcacc atcaccggaa gcgcgatcag gaacaccgat ccccaccagt
    21241 actgcgccag cagcagccca ccgacgagcg gaccggccag gccgcccagc gcgaaacttc
    21301 ccgtccacac gccgagcgcg atccgccgct gtccggggtc ggcgaacatc gtgcggatca
    21361 gcgccagcgt cgacggcatc agcgtcgcac ccgccacccc gagcagcacc cgtgcggcga
    21421 tgagcagctc aggactcggc gcgaacgcgg ccaccgcgga ggcgatcgcg aacagggccg
    21481 caccggccag cagcagccgt cgccggccga tgcggtcacc gaccatgccc atcgtcatca
    21541 gcaggccggc caccacgaag acgtagctgt ccacgatcca caactgctgc gccccggtcg
    21601 gacgcaggtc ggcggtgagc tcgggcacgg cgaggttcag caccgtcgcg tccatcgaga
    21661 ccaccgcgca gggcaacgcc agcacggcca gtccgcacca ctcccggtac ccggcgcgca
    21721 tgctcaccac cacctcacgt gtcacggcat aaatgaagtc atgacgttac gtgaaggctc
    21781 ggccctcctg caacgtcatg agtgccggaa aggcgttact ctggtgaggt gttcatcgaa
    21841 ggtctgcccc ccgccacggt ggtcgccgtg gtcaacggat ggggctcgga gcctcgccgc
    21901 gcgggccacc ggcaggaact gccgccgttg cccgacgcgc tcctgccgcc ctgggccgag
    21961 gcggacgacg ccgggctgga gtgggctgcc gacaggctgt tcccgatctt cgccagcacg
    22021 gatctcactg agcgcgccga gtcgctcgcc gccgtcctcg accgtacgaa ggtccggccg
    22081 accgtccggt acgacgccga gggcttcgcc tccccctggc tggtcgagcc gcggcacgcc
    22141 gtactggctg ccgccgcctt gactcttcgg acgcagttcg ccgagcacga tcccgctcgg
    22201 gtcggcctgt gctcggccgg caactgcgcg gacgtctaca tcgacgtctc ggcgcgagcc
    22261 caccgccggt tctgctcggt cacctgccag aaccggaccc ggacggccgc ctaccgccgc
    22321 cgcagatcag cgacgccctg acgcttcgag caacgcgacg gtccgggtga cgtcgggcaa
    22381 cccgttgatc tcggtctgga tgcgctgggc cgcgcgacgg tggtcctggt cggcgagcac
    22441 ctccgtcacc gtcgcggcga cctcgtccgg gccgaccgtg acggcgtcaa gcacccggcc
    22501 cagcccgagt tccaggcagc gctgggcgtt gtgcggctgg tcggcaccga gcggcagcag
    22561 caccgacggg agaccgtgag ccagagcgcc gagcagactg ccggaaccgc cgtgcgagac
    22621 gaccaggtcg cagtacggca gcagttcctc ctgggggacg aagcgctcga cgcggacgtg
    22681 gcccggctgg gggccgagtg ccgcaggatc gttgcgctcg ccaacggtca cgacaacctt
    22741 cgccggcacc tcacgcagac cggcgagcac ccgggagaac aggtcgtcgg tgtccggccg
    22801 gaagaccgtg cccagcgtga agtagaccgt cggggtttct cgcacggcag cgatcggtac
    22861 gacgtccgcg gtccggtagg agaaggcggt ctgcggcagc gggaagtcgg ggctgcggaa
    22921 gctcggcggg aacggcgaga gcaccagctc ccggtcgagc atcgcgagcc cgggatccgg
    22981 cggcagaccg tactccgccc gcaactgccc cagcggctcg gccaggagtt ccttgcgcac
    23041 cagcgatccg gcggcgagca ccagcacggt cgcgcacgga atgccgagcc gctcggcggc
    23101 gatcgcggac ccgaagtccg cctcgtcccg cacgatcacg tccggcctcc actcccccgc
    23161 gagctccagc agcgcggccg cgtgccgacg ggctccggac cgcccgaacg ccgcggcgaa
    23221 gtgccgctcc tccgccgccg gatccaccgc caccaacggt tccggcgcag ccggcggcgc
    23281 gtcggccacc cgtggcccac tggtgggaaa cgccacgaac cccgccgcct cgaccaccgg
    23341 cgtcaccttg ccggaccccg cgaccgccac cgtgtgcccg gccgcctcca ccgcccgagc
    23401 caccgcgacc aacggccgga agtgtccact tccgccgatg aacgtgaaca agacccgcat
    23461 ccgcgtcacc ctacccagcc cggccggctg ctgccgtgcc tgccgcggtg gaggccggcc
    23521 tacttctccg cgggaccgcg gaggaccacg tagccgaaca gcactgccat cacggcgaag
    23581 ccggcccaca tcgactgctg ccagccgtcg acgaacgact cctgcgccgc gcgcaccagc
    23641 gcgtccgcct gcggtccggc tccgggtgcg gccgcgatcg cgttggccac tccctcgcgg
    23701 gcggtgtcag cggtcccgtg gggcacgccc gggaccgcgg tgagccgggc gtcgatggca
    23761 ctgcggtagc cggcggacag gaccgcgccg agcagcgcga ccccgagcgc cgtaccgaac
    23821 tccctggtga cgtcgttgag cgccgacgcg acgccttggc gctcgcgcgg caacgcgccg
    23881 gtgatcgcct cggtcgacgg cgtcatcgac aggcccatgc cgagtcccat cgccagcatc
    23941 ccggccagca tcgagaggta gccgccgtcg accgagacga acaccgccat caaggccagt
    24001 cccacggccc cgagcaggat cccggacgcc atcgtcgaac gacgtccgat ccgcgcggcc
    24061 agcctcgggg ccaggccgga ggccagcatc atcagcagtg ccatcggcat cagcgcgagc
    24121 gtcgaccgta gcccggacca gccgagcacc gcctggaaga acgggaagag caccacgaag
    24181 atgcccgcca ggacgccgaa aacggccagc agcgacacgg acccgctggc gagtccgcgc
    24241 tcgcggaaga gccgtacgtc gagcaacggg gccggctgac
//
