LOCUS       NC_013729              21074 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Kribbella flavida DSM 17836, complete sequence.
ACCESSION   NC_013729
VERSION     NC_013729.1
KEYWORDS    RefSeq.
SOURCE      Kribbella flavida DSM 17836
  ORGANISM  Kribbella flavida DSM 17836
            Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
            Kribbellaceae; Kribbella.
REFERENCE   1  (bases 1 to 7579488)
  AUTHORS   Pukall,R., Lapidus,A., Glavina Del Rio,T., Copeland,A., Tice,H.,
            Cheng,J.F., Lucas,S., Chen,F., Nolan,M., Labutti,K., Pati,A.,
            Ivanova,N., Mavromatis,K., Mikhailova,N., Pitluck,S., Bruce,D.,
            Goodwin,L., Land,M., Hauser,L., Chang,Y.J., Jeffries,C.D., Chen,A.,
            Palaniappan,K., Chain,P., Rohde,M., Goker,M., Bristow,J.,
            Eisen,J.A., Markowitz,V., Hugenholtz,P., Kyrpides,N.C., Klenk,H.P.
            and Brettin,T.
  TITLE     Complete genome sequence of Kribbella flavida type strain (IFO
            14399)
  JOURNAL   Stand Genomic Sci 2 (2), 186-193 (2010)
   PUBMED   21304701
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     The complete genome of Kribbella flavida DSM 17836
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7579488)
  AUTHORS   Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Kyrpides,N.,
            Mavromatis,K., Ivanova,N., Saunders,E., Brettin,T., Detter,J.C.,
            Han,C., Larimer,F., Land,M., Hauser,L., Markowitz,V., Cheng,J.-F.,
            Hugenholtz,P., Woyke,T., Wu,D., Pukall,R., Klenk,H.-P. and
            Eisen,J.A.
  CONSRTM   US DOE Joint Genome Institute (JGI-PGF)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell
            Drive, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000024345.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:06:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,131
            CDSs (total)                      :: 7,069
            Genes (coding)                    :: 7,033
            CDSs (with protein)               :: 7,033
            Genes (RNA)                       :: 62
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 36
            CDSs (without protein)            :: 36
            Pseudo Genes (ambiguous residues) :: 0 of 36
            Pseudo Genes (frameshifted)       :: 8 of 36
            Pseudo Genes (incomplete)         :: 29 of 36
            Pseudo Genes (internal stop)      :: 4 of 36
            Pseudo Genes (multiple problems)  :: 4 of 36
            ##Genome-Annotation-Data-END##
            ##Metadata-START##
            Organism Display Name             :: Kribbella flavida DSM 17836
            Culture Collection ID :: DSM 17836, JCM 10339, KCTC 9580, NBRC 14399
            GOLD Stamp ID                     :: Gi02235
            Funding Program                   :: DOE-GEBA 2007
            Gene Calling Method               :: GeneMark
            Isolation Site                    :: Soil from China
            Isolation Country                 :: China
            Oxygen Requirement                :: Aerobe
            Cell Shape                        :: Rod-shaped
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Temperature Optimum               :: 28C
            Gram Staining                     :: gram+
            Biotic Relationship               :: Free living
            Diseases                          :: None
            Habitat                           :: Soil
            ##Metadata-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:11:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3016887
            Orig. end                         :: 3037961
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001736.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4082793
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Jonathan A. Eisen (jaeisen@ucdavis.edu)
            David Bruce (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LANL
            Annotation by JGI-ORNL and JGI-PGF
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(197..212)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            complement(1878..2918)
                     /locus_tag="KFLA_RS14090"
                     /old_locus_tag="Kfla_2846"
     CDS             complement(1878..2918)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390340.1"
                     /locus_tag="KFLA_RS14090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2846"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_012920467.1"
                     /transl_table=11
                     /translation="MSSTHTQPTEPAQDVQPSAVSEQHTTAPRSRRRTVAKVLTGFAVP
                     LIAAGLITAGSPGFGQYKVKQGDTLSHIAARYGTTVKTLVALNDLPGNGNAIYAGETLR
                     LPGAQPKQAPRATSSRGRITYLVKSGDTIGGIARRYHVTQRYLLAVNGLQRSDRIYVGK
                     PIQVPVPVAKPIPKKAKKKNNTFAGRIYSDTVVSAADRNRATLKTRKLPGRGQIRSMIV
                     STSKRYGVDPELALAISWQESGWKQRVVSPANAVGAMQVIPSTGRFTSGIVGRKLDLLN
                     PRDNITAGVVLLDHLTSAAKLDIAIAGYYQGLGGVRRNGMYADTKQYVKSVLRIKAQLE
                     SGWNPA"
     misc_feature    2924..2939
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    2971..2986
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    complement(3039..3055)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            complement(3664..4440)
                     /locus_tag="KFLA_RS14095"
                     /old_locus_tag="Kfla_2847"
     CDS             complement(3664..4440)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390339.1"
                     /locus_tag="KFLA_RS14095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2847"
                     /product="thiazole synthase"
                     /protein_id="WP_012920468.1"
                     /transl_table=11
                     /translation="MSDDTLVIAGHELTSRLVMGTGGAPSLEVLEEALVASGTQLTTVA
                     LRRLDPNQQGSVLDVLRKHSIAVLPNTAGCFTAGEAVLTARLAREALETTVIKLEVVAD
                     DHTLLPDPVELLDAAEILVADGFSVLAYTNDDPILARRLEQAGCAAVMPLGAPIGSGLG
                     IRNPHNISMITEAAGVPVVLDAGIGTASEAALAMELGCDAVMLATAVTRAERPALMAAA
                     MRDAVTAGRNARLAGRIPRRYHAAQASSPLEGRAAL"
     gene            complement(4450..4650)
                     /gene="thiS"
                     /locus_tag="KFLA_RS14100"
                     /old_locus_tag="Kfla_2848"
     CDS             complement(4450..4650)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012920469.1"
                     /locus_tag="KFLA_RS14100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2848"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_012920469.1"
                     /transl_table=11
                     /translation="MNVSVNGSTEQLDTGSTVADVVARWARSPVGVAVAVNEAVVTRAE
                     WTATTLAEGDRVEILTAVQGG"
     gene            complement(4659..5849)
                     /gene="thiO"
                     /locus_tag="KFLA_RS14105"
                     /old_locus_tag="Kfla_2849"
     CDS             complement(4659..5849)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390337.1"
                     /locus_tag="KFLA_RS14105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2849"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_012920470.1"
                     /sec_met_domain="DAO (E-value: 8.6e-65, bitscore: 218.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELRSEVVVVGGGLIGLATAWRLAADGIQVTVCDPTPGSQTSSV
                     AAGMLAPVTEVEYGEDALLALNLAGVAAWPAFAEELEAVTGLPAGLHRTGTLSVAYDAD
                     DAAALHRLADYQRRLGLEVEQLTGRETRKREPLLASGVTAGVWVAGDHSVDNRQTVAAL
                     LRAVELTGVQLIRQRVVRVLTTGTTAVGVELDNGDTVLAPHLVAAAGPWTAQLDGIPAE
                     LRPPVRPVKGEILRLQVPKAYRPALNHTVRATARGFSVYLVPRPGGELVVGATTSELGY
                     DTRVLAGGVFALLRDARMVLPVIDELELVETLAGLRPATPDNAPVLGASGLDGLVWATG
                     HYRNGVLLTPITAQVIAETVRTGVLPELAEPFLASRFRSHGGRPQGAPEEVPKVVR"
     gene            5893..6552
                     /gene="thiE"
                     /locus_tag="KFLA_RS14110"
                     /old_locus_tag="Kfla_2850"
     CDS             5893..6552
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390336.1"
                     /locus_tag="KFLA_RS14110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2850"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_012920471.1"
                     /transl_table=11
                     /translation="MTEHTAPLRDRLDAARLYLCTDAREKQGDLEQFLDAALGGGVDIV
                     QLRQKEMEAADELAALEVFADACRRHGKLLAVNDRADVAFTAGADVLHLGQRDLPVPAA
                     RAITGPDVIVGRSTHTFSQVNAAVAEAGSDYFCVGPTWETPTKPGRTAAGLDLVAYAAG
                     RPQVKPWFAIGGIDLERLDEVVEAGATRVVVVRAITEADDPAAAAAEFGRRLRAAG"
     gene            6578..7024
                     /locus_tag="KFLA_RS14115"
                     /old_locus_tag="Kfla_2851"
     CDS             6578..7024
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390335.1"
                     /locus_tag="KFLA_RS14115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2851"
                     /product="ribonuclease domain-containing protein"
                     /protein_id="WP_012920472.1"
                     /transl_table=11
                     /translation="MINNPKIARIVAAVVVAMLVITLAASLFGCGASGQASTRSAAPPA
                     KDPVSGLAFVAAADLPAEARETLKLIDQGGPFPYRRDGVVFGNFERLLPQKQRGYYREY
                     TVRTPGEKDRGARRIVTGKGGERYYTEDHYESFRRVAADEGTGE"
     gene            7021..7449
                     /locus_tag="KFLA_RS14120"
                     /old_locus_tag="Kfla_2852"
     CDS             7021..7449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390334.1"
                     /locus_tag="KFLA_RS14120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2852"
                     /product="barstar family protein"
                     /protein_id="WP_012920473.1"
                     /transl_table=11
                     /translation="MTDLRALLDDGLRPGVYRWRSAATADQVRRSVTSAGWGFVLLDTT
                     AVHDKTGFLDVCATAFDLPRWFGRNWDALADSLGERSTGEPEVVLWEGWRQLLDLDHDT
                     VDVALQIFGEDAGESGQLRIVLREADDVPDLVSDLPVV"
     gene            complement(7446..8171)
                     /locus_tag="KFLA_RS14125"
                     /old_locus_tag="Kfla_2853"
     CDS             complement(7446..8171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390333.1"
                     /locus_tag="KFLA_RS14125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2853"
                     /product="DUF2071 domain-containing protein"
                     /protein_id="WP_012920474.1"
                     /transl_table=11
                     /translation="MAEAVSADAPALPRPRLLRQDWLDLSFLHWAVEPSAIAHHFPPGT
                     APDSFEGLSYVGLVPFRMANIGFPRGPALLQGFLETNVRLYSVDATGRRGVVFLSLDAD
                     RPDAVAAARSVFGLPYRWARMQHQKVDGLHTYTTDLRWPRVAASSSVTVRPGPSLTPGP
                     FEHFLTARWGLHVARAGRTWYLPNEHPAWTLQSAELVDLQDNGLFASVGLPGLSARPPD
                     HVAYSPGVPAVFGLPRQVP"
     misc_feature    8156..8170
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(8194..8520)
                     /locus_tag="KFLA_RS14130"
                     /old_locus_tag="Kfla_2854"
     CDS             complement(8194..8520)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025161.4"
                     /locus_tag="KFLA_RS14130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2854"
                     /product="DUF4180 domain-containing protein"
                     /protein_id="WP_012920475.1"
                     /transl_table=11
                     /translation="MTIDVAETAITDVQSAIDLIGNASYWHRAEWVALTVEQLPAGFFE
                     LSTGVAGEIVQKFAQYGMGLAVVGDVSAYEAASTPFRDWVRESNRGRQLWFVPDLDTLR
                     RLHG"
     gene            complement(8517..9308)
                     /locus_tag="KFLA_RS14135"
                     /old_locus_tag="Kfla_2855"
     CDS             complement(8517..9308)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (39-139). E-value: 6e-14.
                     Score: 44.2. Matches aSDomain:
                     nrpspksdomains_KFLA_RS14135_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020580088.1"
                     /locus_tag="KFLA_RS14135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2855"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_012920476.1"
                     /sec_met_domain="PF00561 (E-value: 1e-10, bitscore: 40.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-08, bitscore:
                     34.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHARYRELLADWPVPSEQRLVDTRQGPTFVVSSGPADAPPLVLL
                     HGSAGTTVDWSGDVPRWSESFRVHAIDGLSEPGLSAPPRPAIGSPAYAEWLDDVLEALG
                     VDRFSIVAMSLGAWFALDYATRRPGRVQRMALLAPTGFSRQKVLRLLPALMLAPLGHWG
                     LRRAVTSVIGPVPAGLSSKYLDFGLLVHKHFVARRVKLPVFTDEQLAGLDLLAIVGSED
                     RMLDSATTARRLPGRSVVIPGAGHLLPLQTERVLDFLRGPR"
     aSDomain        complement(8892..9191)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KFLA_RS14135_Abhydrolase_1.1"
                     /evalue="6.00E-14"
                     /label="KFLA_RS14135_Abhydrolase_1.1"
                     /locus_tag="KFLA_RS14135"
                     /protein_end="139"
                     /protein_start="39"
                     /score="44.2"
                     /tool="antismash"
                     /translation="PPLVLLHGSAGTTVDWSGDVPRWSESFRVHAIDGLSEPGLSAPPR
                     PAIGSPAYAEWLDDVLEALGVDRFSIVAMSLGAWFALDYATRRPGRVQRMALLAP"
     misc_feature    complement(9337..9353)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(9348..9361)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.4"
                     /tool="antismash"
     misc_feature    9372..9386
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.75"
                     /tool="antismash"
     gene            9411..9839
                     /locus_tag="KFLA_RS14140"
                     /old_locus_tag="Kfla_2856"
     CDS             9411..9839
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020580089.1"
                     /locus_tag="KFLA_RS14140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2856"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_012920477.1"
                     /transl_table=11
                     /translation="MRQELYSVEQVAEQLGLHVRTIRNYVRDGKLKATRIGKQYRITRE
                     DLEAFTGTSMAVPAGGGLARHAEVSSIVQIDGLDRAGADRLTTYVTASINQGDLGRLRV
                     ELAYDETREVLKIIVLGDLGVTADLLRLIDMVATSAQP"
     gene            complement(10001..11074)
                     /locus_tag="KFLA_RS14145"
                     /old_locus_tag="Kfla_2857"
     CDS             complement(10001..11074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390332.1"
                     /locus_tag="KFLA_RS14145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2857"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_012920478.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.6e-49, bitscore:
                     165.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHADDADIPTEVQRALTEFLDLQQQRLAEIGPELAEQVQAARDAT
                     SGGKRLRPSFCYWGFRAAGGDPERPILTAAASLEMLHVSALVHDDVMDSSDVRRGAPAA
                     HKRFEALQRARTEASGTGGDPVGFGIGAAILLGDLCLIWADEMMHTSGFDAAALARASK
                     FFDAVRVEVTAGQYLDLVAQASGEADMDRALRVLRYKSATYTVERPLHIGAALGGGDQY
                     LIDALSAYGLPLGEAFQLRDDLLGVFGDPGVTGKPAGDDLREGKRTVLVAYAAEHMSPV
                     QLTEFDRLFGRAELDDDEIQLLREILQDSRAVQACEDLISERTEDALQALDRSPIEDEA
                     SRKALADLAIAATSRQL"
     gene            11131..12045
                     /gene="metF"
                     /locus_tag="KFLA_RS14150"
                     /old_locus_tag="Kfla_2858"
     CDS             11131..12045
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390331.1"
                     /locus_tag="KFLA_RS14150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2858"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_012920479.1"
                     /transl_table=11
                     /translation="MVNGLASTRPGSTPTIRELLATGDRSFSFEFFPPKTPEAEEVLWR
                     SIREIEQLRPTFVSITYGAGGTTRDGTIRVTERVAQDTSLTPLGHLTCVAHSRDELRSV
                     IGAYAGAGVRNVLALRGDPPGGPRQPWVAHPDGLNHAVELVELVRSLGDFCVGVAAFPD
                     KHPEASDLDFDARVLAAKAKAGADYAITQMFFGADDYFQLVDRAAALGCDIPILPGIMP
                     VTNIKQIHRMAELTGMALPTAVTDRLHAVEHDPAAVRAVGIEIASELCDQLLAGGAPGI
                     HFITLNRSTATRQVYLNLQGTTV"
     gene            12133..12663
                     /locus_tag="KFLA_RS14155"
                     /old_locus_tag="Kfla_2859"
     CDS             12133..12663
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390330.1"
                     /locus_tag="KFLA_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2859"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_012920480.1"
                     /transl_table=11
                     /translation="MADPSDLVIDRTLVLLRHAKAVPPESMTDLDRPLAERGRADAAAA
                     GRYLVAEGIEADLVLCSPSVRTRETWQYAAEAGAIATDIWYDRRIYSAGTDGLLDVIQE
                     APAEARTVILIGHAPGVPWLADELALDGTSPNRVELTRKYPTSGLTVLHHTTRWSDLAA
                     DDCDLVSYVVPRG"
     gene            complement(12660..14891)
                     /locus_tag="KFLA_RS14160"
                     /old_locus_tag="Kfla_2860"
     CDS             complement(12660..14891)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390329.1"
                     /locus_tag="KFLA_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2860"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_012920481.1"
                     /transl_table=11
                     /translation="MDQTPTSPDPETVERAELEAEQQHVDRVYDRVAEAARSASRIAVE
                     GHQRAQAQNVGRVREEEQTGLYERDVLVFAAARRIAELDAEHEGLVFGRLDSDGGDDRP
                     AAERAGDLDKLYVGRIGVRDAEYEPLVIDWRAPAAEPFYRATSTDRLGVVRRRVLRNKG
                     ARIIGIEDDLLAPERAPEDLPVMGEGALMASLSRARGHTMRDIVATIQAEQDKAIRAPA
                     RGVTVIGGGPGTGKTVVALHRAAYLLYSDRRRFERGGVLVVGPSAAFMAYIERVLPSLG
                     ENTVSLRAVGELVDGVRATAIDEADVAAIKGSLRMRGVLSRAARDRVPGAPTSLRVFVG
                     GATVELDANQLDNVRRNALRRTPRNRAAAEARKGLVAALWSRFPEDLRNGVYGDRESFG
                     DAVTDLPAYRSFFAAWWPVLTAQAVLRWLGDPRRLTRWARHDLTTAEIETLAAGIAGTD
                     ELTVADVALLDELTTLLGRPPVVEAGKDEEFDWLEGLSDGVNEVLTTSERRARAAAAAD
                     ADEPEEYAHVLVDEAQDLSPMQWRMVTRRGPQASWTIVGDPAQSSWPDPDEARTAMETM
                     LSHLQRHTFRLSTNYRNSAEIYAFAGEVIRQQIPDADLPDAVRRTGVKPELRVFDAGKV
                     AEAAGDAAGELLELVEGTVGVIVPPKLRPGVDAVLAELDNPRIAALTPLESKGLEYDAV
                     VVVEPDRIVSDTLGGVRALYVVLTRATQRMITINSSTHWLPPHGSDGGP"
     gene            complement(14998..16305)
                     /locus_tag="KFLA_RS14165"
                     /old_locus_tag="Kfla_2861"
     CDS             complement(14998..16305)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390328.1"
                     /locus_tag="KFLA_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2861"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_012920482.1"
                     /sec_met_domain="DAO (E-value: 1.5e-09, bitscore: 36.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVIVIGAGLAGLAAAVRLAKLGHQVTVCEAEDRLGGALGRVEA
                     DGFSWDAGAASTTLPAALRDLFRKSGRPIESLVQLDPVTTPRRHLFGDGSVLDLPIGDR
                     SAQLEAWTDLAGERSAQRWTELVDSYGETWQILRKTSLEPPLMDRLPLPAIRALKPWQS
                     LEKVAARRLDDDRTRAVLHYYAVQQGSEARLTPGYVGVWSYLERTFGRWTVAGGFGAVA
                     DALAQRAVERKIDVRTGTEVASVATRDGAVAGVRLVDGTELPAEVVVSDVDPRVLYTQL
                     VTDPAAKKVRKQVERTHQAQAAYVVHLGLREPLPELPFETVLHGAPTVTVRTGGQAPAG
                     HQAWSVLVHGYPTDDVIDLLVARGLHIRDKVVSRQTSASWWAGVAWEGYRTARRRAANT
                     SPVKGLYCVGAGAHPGGGVPATTLGAAVVADAVGKA"
     gene            complement(16305..16916)
                     /locus_tag="KFLA_RS14170"
                     /old_locus_tag="Kfla_2862"
     CDS             complement(16305..16916)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390327.1"
                     /locus_tag="KFLA_RS14170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2862"
                     /product="DUF4126 domain-containing protein"
                     /protein_id="WP_012920483.1"
                     /transl_table=11
                     /translation="MEALPLAFTTGWASGINAYACVLVLGLLGRFADVDDVPTALTGNG
                     VLIAAGALFAVEFVADKIPYVDSAWDTVSTLIRPTVGAVIGALMAGDASNLQQAVAATT
                     GGLVALLSHLIKSSLRLAINTSPEPVTNIAASSGEDVAVLGVVSLAAFHPTAALIVACV
                     LLVIGLIGVYLALRAIRRGLVRFRAWRTGRSNPATGSSTL"
     gene            17084..19000
                     /locus_tag="KFLA_RS14175"
                     /old_locus_tag="Kfla_2863"
     CDS             17084..19000
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020576651.1"
                     /locus_tag="KFLA_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2863"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_012920484.1"
                     /transl_table=11
                     /translation="MRRRPKILAALAVVALPMALTGVSSGGPPPAVASVPSPGLAAAFQ
                     SAAQQYGVPESVLLAVSYAQTRWDDHGGASSTSGGYGPMHLTGVEPTALVERSAGQKLA
                     KADSLRTLYTASDLTGLDPVALRKDPATNIAGGAALLASYQKSLGLPVGADTSPADWYG
                     AIASYSGSPDQVGAATFADDVYAILAAGASRTTNTGQQVSMPAVKVSPLRDQLTRLKLK
                     GGPARPAKSEAECPRSLACEWLPSPYQDLGNGDYGNHDKANRPETGKINYIIVHDTETS
                     WQGTLRLVQDPTYVSWQYTMRSSDGQIWQHVKAKDVAWHAGNWYMNMHSIGIEHEGYAA
                     QGATWYTEALYRNSARLVRYLAEKHDIPLDRAHIIGHDEIPGTLPTTVAGMHWDPGPYW
                     DWERYFELLEAPIYGRSVFPVKAGSIVTIKPGFDDNVQVLTNCTGPGTTCTPQGTNFVY
                     LRQAPDDAAPLVKDIGLRPNAPASTTQVSDIGARAGAGSRYVVAQRSGDWVAVWYLGDL
                     AWFKSPASNPDAFAKPGLVVKPKPGKTTVPVYGRAYPEQAAYPAGIPYQPVTPLQYSIK
                     AGQAYPVGDASIETDYYRATTFDGQPPTDHVQVLGNDRYYQIWFGHRLAYVRAADVDLR
                     PAF"
     gene            complement(19199..19669)
                     /locus_tag="KFLA_RS14180"
                     /old_locus_tag="Kfla_2864"
     CDS             complement(19199..19669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020390324.1"
                     /locus_tag="KFLA_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2864"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_012920485.1"
                     /transl_table=11
                     /translation="MSSHPNVQRVADALRAAGATGEIRILDEAAPTAAAAAAQLGCEVG
                     AIANSLIFDGDGEPVLILTSGAHRVDTGKIAAELGLTKLKRATPEFVKQHTGQPIGGVA
                     PVGHPAPVRTLVDTTLDQYAVVWAAAGIPHSVFPTTYQELLHLTNGIPVAVN"
     gene            complement(19728..20759)
                     /locus_tag="KFLA_RS14185"
                     /old_locus_tag="Kfla_2865"
     CDS             complement(19728..20759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020577004.1"
                     /locus_tag="KFLA_RS14185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Kfla_2865"
                     /product="DUF4037 domain-containing protein"
                     /protein_id="WP_012920486.1"
                     /transl_table=11
                     /translation="MTTFISARELGDNFHAEVIRPLLGDRPYAAGLLGWGSDVLGYDTA
                     RSTDHGWGPRLHVFVDAGEVERVTALIDENLPDEYRGYPVRFGWDTQHPVHHVTVSTVA
                     GWLVDHLGFDASAGISTPDWLITPQQKLLGVVAGRVYADDGRLQPIRDALQWYPDDVWL
                     WMLACQWSRIAQEEPFVQRTHEVGDDLGSRVLAARLVRDAMRLALLLRRTYAPYSKWLG
                     TAFARLGHEDGLDEVLADALAADDLPDRERALVTAYGLLARRHNALGITDEVDPAPRQF
                     HDRPATVLGAERFAEACVGRVRDPRLRGLELVGSIDQCADSTDLLSNPVAYRRLVTLYD
                     GRP"
ORIGIN
        1 ggctgacgac cgagccggcc ggcaccttct cgtcgtactc gtcggtgcgt tcgacggtga
       61 agccggcctt gcgcagcgtg cggctggcta ccttgaccgg cttgccggtg gtgtccggga
      121 cggtgatcgg ccggcggccc tggctgaccc agagattgac cgtgttgccc ggcttcatca
      181 ccgtgtcgaa cttcggcgtg aacgtgatca cccggccggc cggcaccgtc tcgctgtagc
      241 tgtcggtgac ccggccggtg accagcttga tcgagtccag cgcccgcttg gccgcctcca
      301 ggttgagccc ggcgagctgc ggaacgcggt agcgctcggg tcccttggag acgatcagcc
      361 cgatctcgcc gtccttgcgg atccggtcgc cgggcgccgg actggtctcc atcacctggc
      421 cgcgcggcac ggtctcggag aagtcctggt tggccagggt cgtgcgcagg ccgacctcac
      481 ccgccttcgc ggaggcttcc gtggcggtga ggttgagcag caccggcgtc gccgtgtagc
      541 ggtggatgcc gtagtaccaa ccggccgcgc cgacaccgat cgccagggcg aggacggcga
      601 tcagcgcgat cagcccgcgg cccttgcgcg gcggctgcgg cgtcacccgg gtcgccggcg
      661 ggggtggcgc gccacccggc tcgaacggta cgacgatcgt gtcgttgcgc cgggccggct
      721 ggtggtaccc gttcgagtac gccgggtcgt ggtacccgtt cgcggaggcc ggctcgtcgg
      781 cgtactggtc gcggcggtgc tcgacgtaac cggtgccgcg ggtgtagccg tcgtcgtagc
      841 cggactcgtc gcgcatcgcc tgcagcggca cggtcaggtc gccggtcagg tcgggatcgt
      901 ccgggagccc ttcctccagc gcgctccgca cccgccggac ctgccggctc agcacccgcg
      961 cgtcggccgg ccgcagatcc cggtcccggg cggtcgcccg ctgcaccagc gcgtcgacgt
     1021 acggcgggat gcccggctcg agcgcggacg gcggcggcac gtcggcgtgc acgtgggcgt
     1081 aggcgacctg gatcggggtg tcgccggtgt gcggcttgct gccggtcagc agctcgtaga
     1141 gcaggatgcc ggcggagtac acgtcggacc gtgcgtcggc gctgccgtcg gtgacgagct
     1201 cgggagccag gtaggagacc gtgcccatca gcaggccctg ggtcgcggtc tgcccggtcg
     1261 tggtcactgc ccgggcgagg ccgaagtcgg cgaccttgac cgttccctcg tcggagatca
     1321 gcacgttctc gggcttgatg tcgcggtgca cgatgccggc gtcgtgggcc gcggagagcg
     1381 cggacagcac cggcgtcagc aggtcgagcg cgcgggccgg ggacagcggc gcctgctggc
     1441 ggatcacgtc gcgcagcgtc cggccgggca cgtactccat cgccaggaac agcgtgccgt
     1501 cgtcctcgcc ctggtcgaag accgccacca cgttcgggtg cgacagcttc gcggcggccc
     1561 gcgcctcggc gacgaaccgg cggccgaact cggcgtcgtc gcccatgccg aggtgcatca
     1621 ccttgagcgc gacgacccgg tccagccgca tgtcgagggc ctcgtagacg gtcgccatgc
     1681 cgcccttcgc gacgcgcgca cccacgcggt accgccggtc gagcactcgc ccgactaggc
     1741 ggtcgccaac ctgggtgtgt acgtcgtccg tcacgtgcgg tgagccgcct ctcgaagcct
     1801 gtctgcaatg agagtgtaaa taagcggtcc gggcgcggct ccaccgccgc gccgggaccg
     1861 cccagggtca cgcactgcta cgccgggttc cagccgctct ccagctgggc cttgatccgc
     1921 agcacgctct tcacgtactg cttcgtgtcg gcgtacatgc cgttgcgccg tacgccgccg
     1981 aggccctggt agtagccggc gatcgcgatg tcgagcttcg cggcggaggt cagatgatcc
     2041 agcagcacca ccccggcggt gatgttgtcg cgcgggttca gcaggtccag cttgcggccg
     2101 acgatgccgg aagtgaaccg cccggtggac gggatcacct gcatcgcgcc gaccgcgttc
     2161 gccggcgaga cgacgcgctg cttccagccc gactcctgcc aggagatcgc cagcgcgagc
     2221 tcgggatcga cgccgtaccg cttcgaagtg ctgacgatca tcgaccggat ctggccgcgg
     2281 ccgggcagct tgcgggtctt cagcgtggcc cggttccggt cggcggcgct caccacggtg
     2341 tcggagtaga tgcgcccggc aaacgtgttg ttcttcttct tggccttctt cggaatcggt
     2401 ttggcgaccg gcaccgggac ctggatcggc ttgcccacgt agatccggtc gctgcgctgc
     2461 agtccgttca ccgccagcag gtagcgctgc gtgacgtggt accgccgggc gatgccgccg
     2521 atcgtgtcgc cggacttcac caggtaggtg atccgcccgc ggctgctggt cgcccgcggc
     2581 gcctgcttcg gctgcgctcc gggcagccgc agcgtctcac cggcgtagat ggcgttgccg
     2641 ttgcccggca ggtcgttcag cgcgaccagc gtcttcacgg tcgtgccgta ccgcgcggcg
     2701 atgtgactca gcgtgtcacc ctgcttcacc ttgtactggc cgaaccccgg cgagcccgcg
     2761 gtgatcagcc cggccgcgat cagtggcacc gcgaacccgg tcagcacctt cgcgaccgta
     2821 cgccgccggc tccgtggcgc ggtggtgtgt tgctcggaaa ctgcgctcgg ctggacgtct
     2881 tgggcgggct ccgtcggctg agtgtgcgtg ctgctcatca tccatctccc cgtgtcaacg
     2941 tcctttgacc gtaagtggtg gtgctgatga gacaacaggt gtcaacggtg ccgaagttac
     3001 ggctgttacg taagctttac agttcaggac tgaactacat gcatgtggtt cacaatcgtc
     3061 gctccggaag gggtttacgc acagatgccg gtggcaactg atgctggagg catctaatgg
     3121 ggtttgccct ggcggcgggt gggaatccgc ctccgttggg tgtgccgagc cggagcgcga
     3181 tgggttaacc catgagatgc atggttggcc cgccagaatc tgctgggcca accatgcatg
     3241 cgatgggttg acccaccgga gttggcgcga tgcccgggac cacccgcccc agtgcgcgac
     3301 caacccagca tcgctcagcg ccgatcccgt actgcgccga ggtcctgccc cgaagagggt
     3361 ggagcggggt acaacggcta tgccaccacc ggccgggctg tgacaggcag caccgggacg
     3421 accggtgggg gactccacaa ccgcttacgc ggacatccgc accagccgca aaccaccagc
     3481 accgctgagc gacgaccacc cgtactgcgc ggaggtgccg gccgggaaca ggctggcccg
     3541 ggctacgtca ccactgggcg ggtgggctgc aaccggcggc accatgaacc accagagggg
     3601 gagtccacaa ccacctagcc caccaccccg ccgtaccagc cctggcacac gagcgccccg
     3661 acgctacaac gcggctcgac cttccagcgg cgacgacgcc tgcgccgcgt ggtaccggcg
     3721 cgggatccgc cccgccagcc gcgcgttccg tccagcggtg accgcgtcgc gcatcgcggc
     3781 ggccatcagt gccggccgtt cggccctggt gacagccgtc gccagcatga cggcgtcgca
     3841 gccgagctcc atcgccagcg ctgcctcgct ggccgtgccg atcccggcgt ccagcaccac
     3901 cggtacgccg gcggcttcgg tgatcatgct gatgttgtgc gggttgcgga tgccgagtcc
     3961 cgacccgatc ggtgcgccga gcggcatcac cgccgcgcag ccggcctgtt cgagccggcg
     4021 tgcgaggatc gggtcgtcgt tggtgtaggc caggaccgag aagccgtcgg ccaccaggat
     4081 ctcggcggcg tccagcagct cgaccgggtc cggcagcaac gtgtggtcgt cggcaacgac
     4141 ctcgagcttg atcacggtgg tttccagcgc ctcccgcgcc agccgggcgg tcagcacggc
     4201 ttcgccggcc gtgaagcagc cggcggtgtt cggcaggacg gcgatggagt gcttgcgcag
     4261 gacgtcgagc accgagccct gctggttcgg gtccagtcgc cggagcgcga cggtggtcag
     4321 ctgagtgccg gacgcgacca gcgcctcctc cagcacttcg aggctgggtg cgccgccggt
     4381 gcccattacc agccgggacg tcagttcgtg cccggcgatc accagggtgt cgtcgctcat
     4441 ggcttctcct cagccccctt ggaccgcggt gaggatctcc acccggtcgc cctcggccag
     4501 tgtcgtcgcg gtccactccg cacgggtgac cacggcctcg ttcacggcga ccgcgacccc
     4561 gacggggctg cgggcccacc gggcgaccac atcggcgacg gtgctgccgg tgtcgagctg
     4621 ctcggtgctg ccgttgacgg atacgttcat ggcctcgctc acctcactac cttaggcact
     4681 tcctccggcg cgccctgcgg ccggccgccg tgagacctga accggctcgc caggaacggc
     4741 tccgccagct ccggcagtac gccggtccgc acggtttccg cgatcacctg cgccgtgatc
     4801 ggtgtcagca gtacgccgtt gcggtagtgc ccggtcgccc acaccagtcc gtcgagcccg
     4861 gacgccccca gcaccggcgc gttgtccggt gtggccggcc ggagcccggc gagtgtctcg
     4921 accagctcca gctcgtcgat gaccggcagc accatccggg cgtcacgcag cagcgcgaac
     4981 accccgccgg ccaggacccg ggtgtcgtag ccgagctcgg acgtcgtcgc gccgaccacc
     5041 agctcgccgc cgggccgggg gaccaggtag accgagaaac cgcgcgcggt cgctcggacg
     5101 gtgtggttca gggctgggcg ataggccttc gggacctgca ggcgaaggat ctcgcctttg
     5161 accggtcgca cgggcggtcg cagctcggcg ggaatgccgt cgagctgtgc ggtccagggg
     5221 ccggcggccg cgacgaggtg cggcgcgagc acggtgtcgc cgttgtcgag ctcgacgccg
     5281 acagccgtcg taccggtggt gaggacgcgg acgacgcgtt gccggatgag ctgtacgccg
     5341 gtcagctcga ccgcgcgcag cagagcggca accgtctggc ggttgtcgac ggagtggtcg
     5401 cccgcgaccc acacgcccgc ggtgacgccc gaagcgagca agggttcgcg tttgcgggtc
     5461 tcgcggccgg tgagctgctc gacctcaagg cccaggcgtc gttggtagtc ggcgagccgg
     5521 tggagggcgg ccgcgtcgtc ggcgtcgtac gcgaccgaga gcgtgccggt gcggtgcaga
     5581 ccggccggga ggccggtgac cgcctcgagc tcctcggcga aggccggcca ggcggccacg
     5641 ccggcgagat tgagcgccag cagggcgtcc tcgccgtact cgacttcggt gaccggggcg
     5701 agcatgccgg ctgcgaccga ggacgtctga ctgccgggtg tcggatcaca taccgtcacc
     5761 tggataccgt ctgcagcgag ccgccaagcg gtcgccagac cgatcaagcc gccgccgacg
     5821 accacgacct cggatctcag ctcagccatg cggccaagcc tacgacggta tacacatggc
     5881 aggcttgggc ttgtgactga gcacaccgcg ccactccgcg accgactcga cgccgcccgg
     5941 ctctacctgt gcacggacgc cagggagaag cagggcgacc tcgagcagtt cctcgacgca
     6001 gcactcggcg gtggggtcga catcgtccag ctccggcaga aggagatgga ggccgccgac
     6061 gagctcgccg cgctggaggt cttcgccgac gcctgccggc ggcacggcaa gctgctggcg
     6121 gtgaacgacc gggccgacgt cgccttcacc gccggggcgg acgtcctgca cctgggacag
     6181 cgcgacctgc cggtgccggc cgcgcgggcg atcaccggac ccgacgtgat cgtgggccgg
     6241 tcgacgcaca ccttcagcca ggtcaacgcc gcggtcgccg aggccggctc ggactacttc
     6301 tgcgtcgggc cgacctggga gacgccgacc aagccgggcc ggaccgccgc cgggctcgac
     6361 ctcgtcgcct acgccgccgg ccggccgcag gtgaagccgt ggttcgcgat cggcggcatc
     6421 gacctggagc ggctggacga ggtggtcgag gccggcgcga cccgggtggt cgtggtccgc
     6481 gcgatcaccg aggccgacga cccggccgcc gccgccgcgg agttcggccg gcggctgcga
     6541 gcggccggat gaccgcgcgt ccggcgggag tgggccgatg atcaacaacc cgaagatcgc
     6601 ccggatcgtc gcggcggtgg tggtcgcgat gctggtgatc acgctcgccg ccagcctgtt
     6661 cggctgcggc gcgtcgggcc aggcgtcgac ccggtccgcg gccccgcccg cgaaggaccc
     6721 ggtcagcgga ctggccttcg tggccgccgc ggacctgccg gccgaggcgc gggagacgct
     6781 gaagctgatc gatcagggcg gcccgttccc gtaccgccgc gacggcgtgg tgttcggcaa
     6841 cttcgagcgg ctgctgccgc agaagcagcg agggtactac cgggagtaca cggtgaggac
     6901 gcccggcgag aaggaccgcg gcgcccgccg gatcgtgacc ggcaagggcg gtgagcgtta
     6961 ctacaccgaa gatcactacg agtcgttccg ccgggtcgcg gcggacgagg ggaccggcga
     7021 atgaccgacc tgcgcgcgct gctggacgac ggactgcgcc ccggcgtcta ccgctggcgc
     7081 tccgccgcaa ccgccgacca ggtccgtcgc agcgtgacgt cggccggctg gggcttcgtc
     7141 ctgctcgaca cgacggcggt gcacgacaag accggcttcc tcgatgtctg cgcgaccgcg
     7201 ttcgacctgc cgcgctggtt cggccgcaac tgggacgccc tggccgactc tctcggcgag
     7261 cggtccaccg gcgaaccgga ggtggttctc tgggagggct ggcggcagtt gttggacctc
     7321 gaccacgaca cggtcgacgt cgcgctgcag atcttcggcg aggacgccgg cgagtccggc
     7381 cagctgcgga tcgtcctccg cgaggccgac gacgtacccg acctcgtcag cgacctgccg
     7441 gtcgtctagg gcacctggcg cggaaggccg aacaccgccg gtacgccggg gctgtaggcc
     7501 acgtggtccg gtggacgggc gctgagcccg ggcagtccga ccgaggcgaa caagccgttg
     7561 tcctgcaggt cgaccagttc ggcggactgc agcgtccacg ccggatgctc gttcggcagg
     7621 taccaggtgc ggccggcccg ggcgacgtgg aggccccagc gagcggtcag gaagtgctcg
     7681 aaaggccctg gggtcagcga cggccccggg cgcacggtga cgctgcttga cgcggcgacc
     7741 cgcggccagc gcaggtcggt ggtgtaggtg tgcaggccat cgaccttctg gtgctgcatg
     7801 cgggcccagc ggtagggcag gccgaacacc gaccgcgccg cggcgacggc gtccgggcgg
     7861 tcggcgtcga ggctgaggaa gacgacaccg cgccgcccgg tcgcgtccac ggagtacagg
     7921 cggacgttgg tctccaggaa gccctggagc agcgccgggc cgcgcgggaa accgatgttc
     7981 gccatccgga aggggaccag cccgacatag ctgagcccct cgaagctgtc cggcgccgtg
     8041 cccggcggaa agtggtgggc gatggccgac ggctccaccg cccagtgcag gaacgacagg
     8101 tcgagccagt cctggcgcag gagcctgggc cgggggagtg ccggtgcgtc cgcgctgact
     8161 gcttcggcca tacccgcaat ctagccctcg cacctacccg tggagtcgcc gcaaggtgtc
     8221 caggtccggc acgaaccaca gctgccggcc ccggttgctc tcccgcaccc agtcgcggaa
     8281 cggcgtgctc gccgcctcgt acgccgacac gtcgccgacc accgcgagcc ccatcccgta
     8341 ctgcgcgaac ttctgcacga tctccccggc cacgcccgtg ctcagctcga agaacccggc
     8401 cggcaactgc tcgaccgtga gcgcgaccca ctccgcccgg tgccagtacg acgcgttgcc
     8461 gatcaggtcg atcgcgctct gcacgtcggt gatcgcagtc tccgccacgt caatggtcat
     8521 cgcggccccc ggaggaagtc cagcacccgc tcggtctgca gcggcagcag gtgcccggcg
     8581 cccggaatca ccacggaccg tccgggcagt cgccgtgcgg tcgtggccga gtcgagcatg
     8641 cggtcctcgc tgccgactat cgcgagcagg tccagcccgg ccaactgctc gtcggtgaac
     8701 accggcagct tcacccgccg cgcgacgaag tgcttgtgca ccagcaggcc gaagtccagg
     8761 tacttgctgc tcagtcccgc cggcaccgga ccgatcaccg acgtcaccgc gcgccgaaga
     8821 ccccagtgac cgagtggcgc cagcatcagc gcgggcagca gccggagcac cttctgccgg
     8881 ctgaacccgg tcggcgcgag caaggccatt cgctgcaccc gcccgggccg ccgggtcgcg
     8941 tagtcgagcg cgaaccaggc gcccagcgac atcgccacga tcgagaaccg gtcgaccccg
     9001 agcgcttcga gcacgtcgtc cagccactcg gcgtacgccg gggagccgat cgccggtcgg
     9061 ggtggagcgc tcagcccggg ctcgctgagg ccgtcgatcg cgtgcacccg gaagctctcg
     9121 ctccaccgcg gcacgtcgcc cgaccagtcg accgtggtcc cggccgagcc gtgcagcagg
     9181 accagcgggg gcgcatcggc cggaccgctg gagaccacga aggtcgggcc ctggcgggtg
     9241 tccaccaggc gttgctcgct gggcaccggc cagtccgcca gcagctcgcg gtaccgagca
     9301 tgcaccatgg actgtcccgg gagggatcga tacgtcatgt accaaaatta ccctatttat
     9361 ccctattgtg gaatttatag ggaattataa ggaatcgaga gggttggccg atgcggcagg
     9421 agttgtactc ggtggagcag gtcgcggagc agttgggcct gcacgtccgg acgatccgca
     9481 actacgtgcg cgacggcaag ctgaaagcga cccggatcgg caagcagtac cggatcaccc
     9541 gggaggacct ggaggcgttc accggcacct cgatggccgt gccggccggc ggagggctgg
     9601 ctcggcacgc cgaggtgtcg agcatcgtcc agatcgacgg cctcgaccgg gcgggcgccg
     9661 accggctcac cacctacgtg accgcctcga tcaaccaggg cgacctcggc cggctccgcg
     9721 tcgagctcgc gtacgacgag acccgcgagg tgctcaagat catcgtgctc ggcgacctcg
     9781 gcgtgaccgc ggacctgctg cggctgatcg acatggtcgc gacgtcggcc cagccgtagc
     9841 cggccggacc tgcaccactc agcaaccccg cccgcgcagg cgtggcctgg cggggtcagg
     9901 cggccaggac tgcgcgttct gccccacgcg gcgggttgat gagtggtgca ggtccggctc
     9961 cgccttcagt ggtgcccgag tcgacttcgc tggcccggga tcagagctgc cgggaggtcg
    10021 ccgcgatcgc caggtcggcc agcgccttgc gggacgcctc gtcctcgatc ggggagcggt
    10081 ccagcgcctg gagcgcgtcc tcggtccgct cgctgatcag gtcctcgcag gcctgcaccg
    10141 cgcggctgtc ctgcaggatc tcgcgcagca gctggatctc gtcgtcgtcc agctccgccc
    10201 ggccgaacag ccggtcgaac tccgtcagct ggaccggcga catgtgctcg gcggcgtagg
    10261 cgaccaggac cgtgcgcttg ccttcgcgca ggtcgtcgcc ggccggcttg ccggtgacgc
    10321 ccgggtcgcc gaacacgccg agcaggtcgt cgcgcagctg gaacgcctca cccagcggca
    10381 gcccgtacgc cgacagcgcg tcgatcaggt actggtcgcc tccgccgagc gcggcgccga
    10441 tgtgcaacgg ccgctcgacc gtgtaggtgg ccgacttgta ccgcagcacc cgcagcgccc
    10501 ggtccatgtc cgcctcgccg ctggcctgcg cgaccaggtc gaggtactga ccggccgtca
    10561 cctcgacccg gaccgcgtcg aagaacttgg acgcccgggc cagcgctgcc gcgtcgaagc
    10621 cggaggtgtg catcatctcg tcggcccaga tcaggcacag gtcgccgagc aggatcgccg
    10681 cgccgatacc gaagccgacc gggtcgccgc cggtgccgct cgcctccgtc cgggcccgct
    10741 gcaacgcctc gaaccgcttg tgcgcggccg gcgcgccccg gcgtacgtcg gaggagtcca
    10801 tcacgtcgtc gtgcaccagt gcgctgacgt gcagcatctc caggctcgcc gcggcggtca
    10861 ggatcggccg ctcggggtcg cccccggcgg cgcggaaacc ccagtagcag aaggacggcc
    10921 gcagccgctt gccaccgctg gtcgcgtccc gcgcggcctg cacctgctcg gccagctctg
    10981 ggcctatctc ggccagccgc tgctgctgga gatcgaggaa ctcggtcagc gcgcgctgga
    11041 cctcggtcgg gatgtctgcg tcgtcggcat gcacgtctcg gagggtagtc ggtcgacccg
    11101 cgcgagccca tgccccggta gcctgggggg atggtcaacg gtcttgcttc gacgcgtccc
    11161 ggcagcacgc cgacgatccg tgaactgctc gcgacgggtg accgctcctt ctcgttcgag
    11221 ttcttcccgc cgaagacgcc ggaggccgag gaggtgctgt ggcggtcgat ccgcgagatc
    11281 gagcagctcc ggccgacctt cgtctcgatc acgtacggcg ccggcggcac cacccgcgac
    11341 ggcaccatcc gggtcaccga gcgggtcgcc caggacacct cgctgacgcc gctcggccac
    11401 ctcacctgcg tcgcccactc gcgcgacgag ctgcgctcgg tgatcggcgc gtacgccggc
    11461 gccggggtcc gcaacgtgct ggccctgcgc ggcgacccgc cgggcggtcc gcgccagccg
    11521 tgggtcgcgc acccggacgg cctgaaccac gcggtcgagc tggtcgagct ggtccgttcg
    11581 ctcggcgact tctgcgtcgg cgtcgcggcg ttcccggaca agcatcccga ggcgagtgac
    11641 ctcgacttcg acgcccgggt gctggcagcg aaggcgaagg ccggcgcgga ctacgcgatc
    11701 acccagatgt tcttcggcgc cgacgactac ttccagctgg tcgaccgtgc cgcggcgctc
    11761 ggctgcgaca tcccgatcct gcccggcatc atgccggtga cgaacatcaa gcagatccac
    11821 cggatggccg agctcaccgg catggcgctg cccaccgcgg tcaccgaccg cctgcacgcc
    11881 gtcgagcacg acccggcggc ggtccgggcg gtggggatcg agatcgccag cgagctctgc
    11941 gaccaactgc tggccggcgg cgctcccggc atccacttca tcaccctcaa ccgctccacc
    12001 gccacccgcc aggtctacct gaacctgcaa ggcaccacgg tctagccggc cgcccggctc
    12061 gacctctgcc gcgctcggaa cggcgggcgg tgggggctgc gtgcggagtg gtgtgacggc
    12121 tagggtgacg tgatggctga cccgtctgat ctggtgatcg accgcaccct cgtcctgttg
    12181 cggcacgcga aggccgtgcc gccggagtcg atgacggacc tggaccgtcc gctggccgag
    12241 cggggccggg ccgacgccgc cgcggccggc cggtacttgg ttgccgaggg catcgaggcc
    12301 gacctggtgc tgtgctctcc gtcggtccgc acccgggaga cctggcagta cgccgcggag
    12361 gcgggcgcca tcgccaccga catctggtac gaccggcgga tctacagcgc cggcaccgac
    12421 ggcctgctcg acgtgattca ggaagccccg gccgaggccc gcacggtgat cctgatcggc
    12481 cacgccccgg gcgtcccgtg gctcgccgat gagctggccc tcgacggcac cagcccgaac
    12541 cgcgtcgagc tcacccgcaa gtatccgacc agcgggctca ccgtcctgca ccacaccacc
    12601 cgctggtccg acctggccgc cgacgactgc gacctggtct cctacgtcgt gccgcgcggc
    12661 tagggcccgc catcggaccc gtgcggcggg agccagtggg tcgagctgtt gatggtgatc
    12721 atgcgctgcg tcgcccgcgt cagtacgacg tacagcgccc gcacgccgcc gagggtgtcg
    12781 ctgacgatcc ggtccggctc gaccaccacg acggcgtcgt actccaggcc cttggactcc
    12841 agcggggtca gcgcagcgat gcgggggttg tccagctcgg cgagcaccgc gtcgacgccc
    12901 ggccgcagct tcggcggcac gatgacgccg accgtgccct cgaccagctc gagcagttcc
    12961 ccggccgcgt cgccggcggc ctcggcgacc ttgccggcgt cgaagacgcg gagctccggc
    13021 ttgaccccgg tccgccggac cgcgtcgggc aggtccgcgt ccgggatctg ctgccggatc
    13081 acctcgccgg cgaaggcgta gatctccgcc gagttccggt agttcgtcga cagccggaac
    13141 gtgtgccgct gcaggtgcga cagcatcgtc tccatcgcgg tccgggcctc gtccgggtcc
    13201 ggccaggagc tctgcgccgg gtcgccgacg atcgtccagc tggcctgcgg tccgcgccgg
    13261 gtgaccatcc gccactgcat gggggagagg tcctgcgcct cgtcgacgag cacgtgcgcg
    13321 tactcctccg gctcgtccgc gtccgccgcg gccgccgccc gggcccgccg ctccgacgtg
    13381 gtgagcacct cgttgacgcc gtccgacagc ccttccagcc agtcgaactc ctcgtccttg
    13441 ccggcctcca cgaccggcgg ccggccgagc agggtggtca gctcgtcgag cagcgcgacg
    13501 tcggcgacgg tgagctcgtc ggtgccggcg atgccggccg ccagcgtctc gatctcggcc
    13561 gtggtcaggt cgtgccgggc ccagcgggtc agccggcgcg ggtcgccgag ccagcgcagg
    13621 acggcctgcg cggtcagcac cggccaccac gccgcgaaga acgaccggta cgccggcagg
    13681 tcggtgaccg cgtcgccgaa cgactcgcga tcgccgtaca cgccgttgcg caggtcctcg
    13741 gggaagcggc tccacagcgc ggcgaccagc cccttgcggg cttcggcggc ggcacggttg
    13801 cgcggcgtcc gacgcagcgc gttgcggcgg acgttgtcga gctggttcgc gtcgagttcg
    13861 accgtggcgc cgccgacgaa cacccgcaag ctggtcggcg cgccgggcac ccggtcgcgc
    13921 gcggcgcggg acagcacgcc gcgcatccgc agcgagccct tgatcgcggc gacgtcggcc
    13981 tcgtcgatcg cggtcgcccg gacgccgtcg accagttcgc ccaccgcgcg cagggagacc
    14041 gtgttctcgc cgaggctggg cagcacccgc tcgatgtagg ccatgaacgc ggccgacggg
    14101 ccgaccacca gcaccccgcc gcgctcgaac cgccgccggt cgctgtagag caggtacgcc
    14161 gcgcggtgca gcgccacgac cgtcttgccg gtgccgggac cgccgccgat cacggtgacg
    14221 ccgcgggcgg gggcccggat cgccttgtcc tgctcggcct ggatggtggc gacgatgtcg
    14281 cgcatcgtgt ggccccgggc ccgtgacagc gacgccatca gcgcgccctc gcccatcacc
    14341 ggcaggtcct ccggcgcgcg ctccggcgcc agcaggtcgt cctcgatgcc gatgatccgg
    14401 gcgcccttgt tgcgcagcac ccggcgtcgg acgacgccca gccggtcggt cgaggtggcc
    14461 cggtagaacg gctcggcggc aggcgcccgc cagtcgatca ccagcggctc gtactccgcg
    14521 tcgcggacgc cgatccggcc gacgtacagc ttgtccaggt cgccggcccg ctcggccgcg
    14581 ggccggtcgt cgccgccgtc ggagtcgagc cggccgaaca ccaggccctc gtgctcggcg
    14641 tccagctccg cgatccgccg ggcggcggcg aagacgagca cgtcgcgctc gtacagcccg
    14701 gtctgctcct cctcgcggac ccggccgacg ttctgcgcct gggcacgctg gtgcccctcg
    14761 accgcgatcc tggacgcgga ccgggcggcc tccgcgaccc ggtcgtagac ccggtcgaca
    14821 tgctgctgct cggcctccag ctcagcccgc tcgaccgtct cgggatcggg tgacgtgggg
    14881 gtttggtcca ccggggtcct ctctactgcc ggggacactt cccccgacac ggaacacatg
    14941 aacgatcaat cttagtgcgc gcttgcggcc gaccccaggc cggtcccacc gcgagcttca
    15001 ggccttgccg acggcgtcgg ccacgacggc cgcgccgagc gtcgtcgcgg gcaccccgcc
    15061 gccgggatgc gcgcccgcgc cgacgcagta caggcctttg accggtgagg tgttcgcggc
    15121 ccggcgacgg gccgtccggt acccctccca ggcgacgccg gcccaccacg acgcggacgt
    15181 ctggcgggag acgaccttgt cccggatgtg cagcccgcgg gcgaccagca ggtcgatcac
    15241 gtcgtcggtg gggtagccgt gcaccagcac cgaccaggcc tggtgacctg ccggcgcctg
    15301 cccaccggtg cggacggtga ccgtcggcgc cccgtgcagc acggtctcga agggcagctc
    15361 cggcagcggc tcccgcagcc cgagatggac gacgtacgcc gcctgggcct ggtgcgtgcg
    15421 ctcgacctgc ttgcggacct tcttggccgc cgggtcggtg acgagctggg tgtagagcac
    15481 ccggggatcg acgtcgctca ccacgacttc ggccggcagc tcggttccgt cgaccagccg
    15541 gaccccggcg accgcgccgt cccgggtggc gaccgacgcc acctcggtgc cggtgcggac
    15601 gtcgatcttg cgctcgaccg cgcgctgggc cagggcgtcc gcgaccgcgc cgaagccgcc
    15661 ggcgacggtc cagcggccga aggtgcgttc gaggtaggac cagacgccga cgtagccggg
    15721 cgtcagccgg gcctcggagc cctgctggac ggcgtagtag tgcaggacgg cccgcgtccg
    15781 gtcgtcgtcg agccggcgcg cggcgacctt ctcgagcgac tgccacggct tgagcgcgcg
    15841 gatcgcgggg agcggcagcc ggtccatcag cggcggctcc agcgaggtct tgcgcaggat
    15901 ctgccaggtc tcgccgtagc tgtcgaccag ttcggtccag cgctgggcgg atctctcgcc
    15961 ggccaagtcg gtccacgcct cgagttgcgc cgagcggtcg ccgatcggca ggtcgagcac
    16021 ggagccgtcg ccgaacaggt gccgccgcgg cgtggtgacc ggatccagct ggaccaggct
    16081 ctcgatcggc cggccggact tgcggaacaa gtcgcgcagc gcggccggca gcgtcgtact
    16141 ggcggcgccg gcgtcccagc tgaagccgtc ggcctcgacc cggcccagcg cgccgccgag
    16201 gcggtcctcg gcctcgcaaa cggtgacctg gtggccgagc ttggccagtc gtacggcggc
    16261 ggcgagaccg gcgaggccgg ccccgatgac gatcacgcgg gccatcagag ggtgctgctc
    16321 ccagtcgctg gattgcttcg tcccgtccgc caggcccgga acctgaccag gccgcgccgg
    16381 atcgcgcgca gcgcgaggta gacgccgatc agcccgatca ccagcagcac gcaggccacg
    16441 atcagggcgg cggtcgggtg gaacgcggcc agcgacacca cgccgagcac ggcgacgtcc
    16501 tcgccggacg aggcggcgat gttggtcacc ggctcggggg aggtgttgat cgccagccgc
    16561 aggctcgact tgatcaggtg cgagagcagc gcgaccaggc cgccggtggt ggcggcgacc
    16621 gcctgctgca ggttgctcgc gtcgccggcc atcagcgcgc cgatcaccgc cccgacggtc
    16681 ggccggatca gcgtggagac ggtgtcccag gccgagtcga cgtaggggat cttgtccgcg
    16741 acgaactcga ccgcgaacag ggcgccggcg gcgatcagca cgccgttccc ggtcagtgcg
    16801 gtgggcacgt cgtcgacgtc ggcgaaccgg ccgagcagtc cgagcaccag cacgcaggcg
    16861 tacgcgttga tcccgctcgc ccagccggtg gtgaacgcca acggcaacgc ttccatgctg
    16921 ctcctgtacc cctctgccgc cgccccgagc gaccactgtc ggtcactatc gaaccgtgag
    16981 gcccgaatct tagttaaccg ttgacatccg ctcggccccg accgagagtg aacgggctgc
    17041 cggtctgtgt gaccgccaca ccccagatca gggagatacg aacatgcgtc gtcgtccgaa
    17101 gattctcgcc gcactggcag tggtagcgct gcccatggcc ttgaccggcg tgtcgtccgg
    17161 cggtccaccg cccgctgtcg cgtccgtccc cagccctggc ctcgccgccg cgttccagtc
    17221 cgccgcacaa cagtacggcg taccggagtc ggtgctgctg gccgtgtcct acgcgcagac
    17281 gcgctgggac gaccatgggg gtgcctcgag cacgtcgggc ggctacgggc cgatgcacct
    17341 gaccggcgtc gagcccactg cgctggtgga gcgctcggcc gggcagaagc tcgccaaggc
    17401 cgactcgctg cgcacgctgt acaccgcctc cgacctgacc ggcctggacc cggtcgccct
    17461 gcgcaaggac ccggcgacga acatcgccgg tggcgccgcg ctgctcgcgt cgtaccagaa
    17521 gtcgctgggg ctgcccgtcg gcgccgacac ctcgcccgcc gactggtacg gcgccatcgc
    17581 gtcgtactcc ggttcgccgg accaggtcgg cgccgcgacc ttcgccgacg acgtctacgc
    17641 gatcctggcc gccggtgcga gccggacgac gaacaccggg cagcaggtga gcatgccggc
    17701 ggtgaaggtg tccccgctgc gcgaccagct gacccggctg aagctgaagg gcggcccggc
    17761 gcgtcccgcg aagtccgagg cggagtgccc gcgctcgctg gcctgcgagt ggctgccctc
    17821 gccgtaccag gacctcggca acggtgacta cggcaaccac gacaaggcga accggccgga
    17881 gaccggcaag atcaactaca tcatcgtgca cgacacggag accagctggc agggcacgct
    17941 acgcctggtg caggacccga cgtacgtgag ctggcagtac acgatgcgct cgtccgacgg
    18001 acagatctgg cagcacgtga aggccaagga cgtcgcctgg catgccggca actggtacat
    18061 gaacatgcac agcatcggca tcgagcacga gggctacgcc gcgcagggcg caacctggta
    18121 caccgaggcg ctctaccgca actcggcgcg gctggtgcgc tacctggcgg agaagcacga
    18181 catcccgctg gaccgcgcgc acatcatcgg tcacgacgag atcccgggca cgctgccgac
    18241 cacggtggcc ggcatgcact gggacccggg accgtactgg gactgggagc gctacttcga
    18301 gctgctcgag gcgccgatct acgggcgcag cgtgttcccg gtgaaggccg gctcgatcgt
    18361 gacgatcaag cccggtttcg acgacaacgt ccaggtgctc accaactgca ccggtcccgg
    18421 caccacctgc acgccgcagg gcacgaactt cgtctacctg cgccaggcgc cggacgacgc
    18481 cgccccgctg gtgaaggaca tcgggctgcg gcccaacgcg ccggcgtcca ccacgcaggt
    18541 gtcggacatc ggggcccgtg cgggcgccgg ctcgcggtac gtcgtggcgc agcgctcggg
    18601 tgactgggtg gcggtctggt acctcggcga cctggcctgg ttcaagagtc ccgcctcgaa
    18661 ccccgacgcc ttcgcgaagc ccggcctcgt ggtgaagccg aagcccggca agaccacggt
    18721 cccggtctac ggccgcgcgt acccggagca ggcggcgtac ccggcgggca ttccgtacca
    18781 gccggtgacc ccgctgcagt actcgatcaa ggccggccag gcgtacccgg tgggtgacgc
    18841 gagcatcgag accgactact accgagccac caccttcgac ggccagccgc ccaccgacca
    18901 cgtccaggtc ctcggcaacg accgctacta ccagatttgg ttcggccacc ggctggccta
    18961 cgtccgcgcc gccgacgtag acctccgccc ggcgttctga ccttccggag ttcgagcgaa
    19021 tgaccgacga agccgtccag cgcctgctgg acggcttcgt cgtctccatc accacaacac
    19081 tgcggtgatc ggcgctaccg catccccgcg ggccggcgct cgctgcgctg gcgtctgcgg
    19141 cgtgcggagc tcacccgtag ctacctccgg gaccggattc cggctgccgc gtccggaatc
    19201 agttgacggc gaccgggatg ccgttggtga ggtggaggag ttcctggtag gtggtgggga
    19261 agaccgagtg cgggatgccg gctgctgccc agaccacggc gtactggtcg agggtggtgt
    19321 cgaccagcgt gcggacgggt gcggggtggc ctactggggc gaccccgccg atgggctggc
    19381 cggtgtgctg cttcacgaac tccggcgtgg cccgcttgag cttggtgagg ccgagctcgg
    19441 cggcgatctt cccggtgtcg acccggtggg cgccggaggt caggatcagc accggctcgc
    19501 cgtcgccgtc gaagatcagg ctgttggcga tcgccccgac ctcgcagccg agctgcgccg
    19561 ccgcggccgc cgcggtgggc gccgcctcgt cgaggatccg gatctcgccg gtcgcaccgg
    19621 ccgcccgcaa cgcgtcggcc acgcgctgca cgttgggatg actactcacg ctctggattc
    19681 cttgccttct cgttgtcctg acatcgcttc gtgcctgggc agcccggtca cggccgcccg
    19741 tcgtacaggg tgaccagccg tcggtaggcg actggattgc tcagcagatc ggtgctgtcg
    19801 gcacattgat cgatcgaccc gaccagctcc aggccacgca gccgcggatc ccgcacccgt
    19861 ccgacgcacg cctcggcgaa ccgctcggcc ccgaggaccg tcgccggccg gtcgtggaac
    19921 tgccgcggcg ccgggtccac ctcgtcggtg atccccagcg cgttgtgccg ccgcgccagc
    19981 agcccgtacg ccgtgaccag cgctcgctcg cgatccggca ggtcgtccgc cgccagcgcg
    20041 tcagccagga cctcgtcgag cccgtcctcg tgcccgagcc gcgcgaacgc cgtaccgagc
    20101 catttcgagt acggcgcgta ggtgcggcgc aacagcaacg ccagccgcat cgcgtcgcgc
    20161 accagtcgag ccgcgagcac ccgggacccc aggtcgtcgc cgacctcgtg ggtgcgctgg
    20221 acgaacggct cctcctgcgc gatccgcgac cactggcagg cgagcatcca gagccacacg
    20281 tcgtccgggt accactgaag ggcatcgcgg atcggctgca gccggccgtc gtcggcgtac
    20341 acgcggccgg cgacgacgcc gagcagtttc tgctgcggcg tgatcagcca gtccggcgta
    20401 ctgattccgg cgctcgcgtc gaagccgagg tggtcgacga gccacccggc gaccgtgctc
    20461 acggtgacgt ggtgcacggg gtgctgggtg tcccagccga acctgacggg atacccgcgg
    20521 tactcgtcgg gcaggttctc gtcgatcagc gcggtgaccc gctcgacttc gcctgcgtcg
    20581 acgaacacgt gcaacctggg cccccagccg tggtccgtcg accgggccgt gtcgtagccg
    20641 aggacatcgg atccccagcc gagcaggcct gcggcgtacg ggcggtcgcc gagcagcggc
    20701 cggatcacct cggcatggaa gttgtcgccg agctcgcgcg ccgagatgaa cgtcgtcatg
    20761 gcaacgaccc tagttgcggg cgtcggcggg agcacatccg ttgtcggcgg ctcaggtcgc
    20821 ggcgagttgc gcggcgccga acgagacgtt gaaccggtcg caccagatcg agacgctgcg
    20881 gaaaccggac aggtcgagct cggcggggat gacgtagttc tgccggccgc ggttgccctt
    20941 gagcttgccg aggttgtggt agctgccgtc gtcgaacacg tgccagcccg ccctgcccgg
    21001 caggaccggg gcgtcgctca gccagacctt caggtcgggc ccgtcggagg tgtcgaggtc
    21061 ctccaggcgc agga
//
