LOCUS       NC_010632              20648 bp    DNA     circular CON 15-MAR-2024
DEFINITION  Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence.
ACCESSION   NC_010632
VERSION     NC_010632.1
KEYWORDS    RefSeq.
SOURCE      Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)
  ORGANISM  Nostoc punctiforme PCC 73102
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Nostoc.
REFERENCE   1  (bases 1 to 254918)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M., Vergez,L.,
            Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N., Kim,E.,
            Meeks,J.C., Elhai,J., Campbell,E.L., Thiel,T., Longmire,J., Potts,M.
            and Atlas,R.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of plasmid2 of Nostoc punctiforme ATCC 29133
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 254918)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Glavina del Rio,T., Dalin,E.,
            Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M., Vergez,L.,
            Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N., Kim,E.,
            Meeks,J.C., Elhai,J., Campbell,E.L., Thiel,T., Longmire,J., Potts,M.
            and Atlas,R.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (07-APR-2008) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000020025.1-RS_2024_03_15
            Annotation Date                   :: 03/15/2024 03:30:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,702
            CDSs (total)                      :: 7,602
            Genes (coding)                    :: 7,314
            CDSs (with protein)               :: 7,314
            Genes (RNA)                       :: 100
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 288
            CDSs (without protein)            :: 288
            Pseudo Genes (ambiguous residues) :: 0 of 288
            Pseudo Genes (frameshifted)       :: 133 of 288
            Pseudo Genes (incomplete)         :: 166 of 288
            Pseudo Genes (internal stop)      :: 86 of 288
            Pseudo Genes (multiple problems)  :: 85 of 288
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:28:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 113693
            Orig. end                         :: 134341
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP001039.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 2351359
            Source DNA available from John C. Meeks (jcMeeks@ucdavis.edu)
            Bacteria available from ATCC: ATCC 29133
            Contacts: John C. Meeks (jcMeeks@ucdavis.edu)
            David Bruce (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LLNL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20648
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20648
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20648
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10648](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10648)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(355..369)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.7"
                     /tool="antismash"
     gene            470..667
                     /locus_tag="NPUN_RS35800"
                     /old_locus_tag="Npun_BF115"
     CDS             470..667
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS35800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Npun_BF115"
                     /product="hypothetical protein"
                     /protein_id="WP_148220497.1"
                     /transl_table=11
                     /translation="MPERYMLSITLSEKAYEEFRLVATWKKIPIGTLIRQILEREHESQ
                     AFGELVKRAMADGQLNVSED"
     gene            759..1409
                     /locus_tag="NPUN_RS38110"
                     /old_locus_tag="Npun_BF116"
     CDS             759..1409
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022019.4"
                     /locus_tag="NPUN_RS38110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BF116"
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="WP_012413264.1"
                     /transl_table=11
                     /translation="MQLKEEFYEHYKKNNGWVYLVHAEGTLRFKIGRSINPIGRLSQLQ
                     GQSPYPLVIQECIWTPDAIYYEQYLHQEFGKCRVFGEWFEFVEPWDLSNAYNKFRWYGR
                     TDISDISDCIFSWFVNRFYEVKPFCHLEAFTQINSIIQETLATSQCLDDLAVTIDFFLE
                     YLFETWITKKFNICHIYDETEHFLDFACFFKGLRERTDCFIYGLHRGKTYEFI"
     gene            1396..2901
                     /locus_tag="NPUN_RS42625"
                     /old_locus_tag="Npun_BF117"
     CDS             1396..2901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012413036.1"
                     /locus_tag="NPUN_RS42625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BF117"
                     /product="hypothetical protein"
                     /protein_id="WP_012413265.1"
                     /transl_table=11
                     /translation="MSLSNNTKTLESRKNNKYAEILGSPIAFHRVYATIAGSASAGLFL
                     SQAMYWNSRTNDPQGWFYKTYEQWTSETALNRYELDKIRHHLTTINILETQLKGSPARL
                     YYRINHKVLNNFLDAIKKGSFTSIRPKNKNTKKYSQISESVDSQQTGSVCLPSTNLSAE
                     GQQASPMTLNNPSCSRSTNSIYIESTEITSKITSEITHNAPLASLPAPPTQESVCEKEE
                     LDLTTKEIELEEPTPEKPSLEESTPEEPTPQQPTSLLKNSESLQQTDNPSRGSTIAAES
                     FEKSEQANKLQLTCPYKTAQNVKELIDAWLTDPTAMSDDSLPLLVRETIKWNRWVLPWR
                     NGERKLNNLYQNFNPVVVDFLAQELATKSKRSARQEIDHAIAVMNTWEKTKGGWTNLMQ
                     RYHQALQTEKQPLPQQRTALAHKVKNITSSSLEDALAQDRIRRQQEQSIQVPSNGYQHS
                     PQMLELKVKLQAKANEPKVLSNTRPSSTNLREVEAQLKLALRA"
     gene            2904..4253
                     /locus_tag="NPUN_RS35815"
                     /old_locus_tag="Npun_BF118"
     CDS             2904..4253
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012413266.1"
                     /locus_tag="NPUN_RS35815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BF118"
                     /product="DnaB-like helicase C-terminal domain-containing
                     protein"
                     /protein_id="WP_012413266.1"
                     /transl_table=11
                     /translation="MHSNQDNVVSFHPDRSLDNLPPQNIEAEEAILGGIMLDPEAMTRV
                     SDRLSIEAFYINAHKDIYQAAVRLHATYQPTDLLSVTAWLADHNLLNRIGGRNKLATLV
                     DRTVSAVNIDALADLVMEKYRRRQLIKVGNEIVQLGYETQTELPLVLGQAEAKVFTVTQ
                     NQSDERSLVFSAQDMGIELFQKLEMGNMAGEKVGWYDLETIIGGIYPSSLVVVAAESHM
                     GKTHFMISYAYEIMTKLGKPVLYVTPEMDKNQLNARMLARITGVDASMIQTNTQCYWEQ
                     IAQGIGQMVELPWKVYEHSSPTTAMIASAVRRAIAEFDGSIGAVFIDYLQQIPLESGGN
                     MAFEVGKITRQIRDIAKSHKIPVFLGCQINRGNQTTADKRPNRHLLRNSGEIFEVCDQL
                     IMLYRDAVYTKDPSDRTIELIVEKNRLYGKLGTATMLCDLSTSKFLNLAR"
     gene            4295..4699
                     /locus_tag="NPUN_RS35820"
                     /old_locus_tag="Npun_BF119"
     CDS             4295..4699
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011316618.1"
                     /locus_tag="NPUN_RS35820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BF119"
                     /product="ASCH domain-containing protein"
                     /protein_id="WP_012413267.1"
                     /transl_table=11
                     /translation="MKALSVRQPWAWAIIYALKNVENRGWPIHYRGDILIHAAKTCTKK
                     EYQVAEEFGHCMGVVIPELISLRRGQVIGIVTIVDCQFSQVASGWGMPGQYHWKLENPR
                     EITPIPYIGQLGIFEVPDDLVREAIAHNQI"
     gene            4894..5559
                     /locus_tag="NPUN_RS35825"
     CDS             4894..5559
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /locus_tag="NPUN_RS35825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_234711206.1"
                     /transl_table=11
                     /translation="MSVTQKILKVGDGPTTGKEKVGGIWKGRSIGSIPCGAVTMIRSLQ
                     QQGADREDIIAFIKKAKTKNYSPKILDVCKNFNNTNFKPTLPDDAPIAVVLFAGGGGIE
                     AGMVEAGIRPVIAVEFDPTKPELSRAIALTHHCNFSEYGCRVVQLTVQEVAQSGFIGFP
                     RYPDYLHASPVCANFSLAHTAKAGKGIESADDLTAAASVAEAIRQLQPRVFTLENVPR"
     gene            5617..6057
                     /locus_tag="NPUN_RS35830"
     CDS             5617..6057
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024954.4"
                     /locus_tag="NPUN_RS35830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_041566678.1"
                     /transl_table=11
                     /translation="MPKVLKIILNSEEDRTLKELSCADGVARRTKQRATALRLNAHGWN
                     VPQIAEYLDWAQQTVRQTIRRWELQGLGGLWERPGRGKKRSWHEVDWQVVEKCLGQNRR
                     YSARQLSQKLLEERQIELGAEQIRRLLKKRGGIGNVSATVRL"
     gene            6036..6668
                     /locus_tag="NPUN_RS35835"
     CDS             6036..6668
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /locus_tag="NPUN_RS35835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_052304744.1"
                     /transl_table=11
                     /translation="MRYCPALNLKKEYLQAKRLDWELLKLWSQLGLVCLKYLDESGCYC
                     TSPTDYAYGRRGEQKRIRQNRRRGRRINIFGIWEPKVRFDYALMVGTLKTPTYVQLMNW
                     QAQTAATRLLETGQITAIIHDNASVHKSSLACQQHQRWQQQGLYIFFLPPYSPQMNRIE
                     DEWLHLKRDELAGQVFEDEYELAIAIIDGINNRANHGHYQVERFTFN"
     gene            6777..7139
                     /locus_tag="NPUN_RS43930"
     CDS             6777..7139
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS43930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_041566679.1"
                     /transl_table=11
                     /translation="MPQARRRVVLIANKGFQVGLPLGTTPCDWYEAFTKCAEGIAHLIP
                     TMTDSQLLLKQQQALEKFLAGNAPTPLLIERVGGRTESKYKPGHLPCNTILRSPPAGGY
                     AIALHGSQGLQPEQVR"
     misc_feature    complement(6811..6824)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     gene            7054..7335
                     /locus_tag="NPUN_RS44615"
     CDS             7054..7335
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /locus_tag="NPUN_RS44615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA cytosine methyltransferase"
                     /protein_id="WP_336884965.1"
                     /transl_table=11
                     /translation="MPSCDRLRRAGTPSHFTDHKGCNRSKFADIWLPDGTVKSLTIQGT
                     AILQGFPSWYEFPKETTTAGSIIGYSVPPSFAAQLFTHIQKQLSGAFL"
     gene            7217..7477
                     /locus_tag="NPUN_RS44620"
     CDS             7217..7477
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS44620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167315721.1"
                     /transl_table=11
                     /translation="MSSQKRLLRLGQLSAILYLPVLPRSYLLTYRNNYQEHFYDKPRAT
                     HLKCVGTGKEEDNQQAGDRKEEAQRLCGGSEFPPALMVFFP"
     gene            complement(7635..7811)
                     /locus_tag="NPUN_RS41340"
     CDS             complement(7635..7811)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS41340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_193372292.1"
                     /transl_table=11
                     /translation="MGKSKSVDVTGGMAKKVEEFLTISNLGIDCWIIDGNIPGNLASSV
                     LGTPTLGTLIRAF"
     gene            complement(7946..8968)
                     /locus_tag="NPUN_RS35850"
                     /old_locus_tag="Npun_BR123"
     CDS             complement(7946..8968)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612256.1"
                     /locus_tag="NPUN_RS35850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR123"
                     /product="IS4 family transposase"
                     /protein_id="WP_012408090.1"
                     /transl_table=11
                     /translation="MIINSFPKIVKDILRGLPKNDYPVLNSRLFFECWLSYAMDNSLTS
                     MRDLFNRLNNTGFPVDISTFSKANLHRSQKPFQEIYQKLNELVQKKVQKKLHDKYAICP
                     IDSTIITLTSKLLWVLGHHQVKLFSSLNLATGSPSDNFINFGHDHDYKFGCKMMSSLPN
                     NAVGVMDRGFAGLKFIQELVQENKYFVLRVKNNWKLEFEEQTGLIKVGASNDAQAYRVI
                     NFCDLETKTEFRLVTNLPTLGEAAVSDYEIRDIYRLRWGVELLWKFLKMHLKLDKLITK
                     NVNGITIQIYVTLIAYLILQILSVPQQWGHTLLDKFRYLQSCMCQKISYVHWFEEMMSC
                     "
     gene            complement(8874..9626)
                     /locus_tag="NPUN_RS38435"
                     /old_locus_tag="Npun_BR124"
     CDS             complement(8874..9626)
                     /EC_number="2.7.4.26"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017322564.1"
                     /locus_tag="NPUN_RS38435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR124"
                     /product="isopentenyl phosphate kinase"
                     /protein_id="WP_234711207.1"
                     /transl_table=11
                     /translation="MELVLVKLGGSLITDKDKPYTARREVITQLVEQVSLIKRENPNLK
                     LIIGNGAGSFAHQSANKYNTINGFSGDEEKLGFCLVHQDALDLNFLLAKSFLQVGLPVV
                     SLPPISMIITHNKKLLKSDFSGIESSLQAGLIPLVFGDVVLDQAIGGTVFSTDAMLAEL
                     AKYFYLQGKFKVRLINVGNYAGVYDRAKVLNVKKNPIKTAQNMLNFGRKIKVYLFNSDY
                     KFISQDCQRYLERTAKKRLSSIEQSSVL"
     gene            complement(10001..10648)
                     /locus_tag="NPUN_RS35860"
                     /old_locus_tag="Npun_BR125"
     CDS             complement(10001..10648)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_Pyr4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008300425.1"
                     /locus_tag="NPUN_RS35860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR125"
                     /product="hypothetical protein"
                     /protein_id="WP_012413268.1"
                     /sec_met_domain="TS_Pyr4 (E-value: 3.2e-35, bitscore:
                     115.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTYLMLGSGAFWILTYILLIQRGFKDQTYGMPLVALCANLSWEF
                     IFSFIHPHQPPQLQINIVWLMLDLIILYGFFKFGQSELKDIPNKLFYPVFILTLFTSFC
                     CVLLITDEFQDWSGAYTAFGQNLLMSILFIDMLTKRNTVRGQSIFIAIFKMIGTLLASI
                     GFYINHPTQGRSLLFIFLYTAIFVFDLIYAGMIAMKIKSFEKKKLNHALTRQ"
     gene            complement(11447..11614)
                     /locus_tag="NPUN_RS42405"
                     /old_locus_tag="Npun_BR127"
     CDS             complement(11447..11614)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012413270.1"
                     /locus_tag="NPUN_RS42405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR127"
                     /product="hypothetical protein"
                     /protein_id="WP_012413270.1"
                     /transl_table=11
                     /translation="MIKPKNVYRGHSMEKVGYGKRAVFKTTINEREWSAVTELEVKTAI
                     DAWIDEGIEP"
     gene            complement(11751..12920)
                     /locus_tag="NPUN_RS35870"
                     /old_locus_tag="Npun_BR128"
     CDS             complement(11751..12920)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006195886.1"
                     /locus_tag="NPUN_RS35870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR128"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_012413271.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.8e-24,
                     bitscore: 78.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKLKISLLVWNLSTNDGFIRASLLKSALEKLGYETEILGFLFN
                     KNLSAAIPSDTKLFAIEGGNYPKFFPAVNKVLKHIDGDIIYAIKPQIASFGVALLKSLY
                     SRKPVILDIDDWELSWHGGDNWRYCPTLKQLARDLLKSDGALRSPYHPLYVKWMEGLVN
                     HADAVTVHTKFLQQRFGGMLVPNGKDTSLFDPAQCNPDSSRSRYNLSEYRILMFPGAPR
                     PYKGLEDVLIALEKINQPDLKLVIIGGSPYDDYDQQLQQRWGRWIIKLPKYPVDAMPDL
                     VAAAHIVVVPQRDTPETRAQFPLKLTDGMAMAKPVLSTRVGDIPEILGDTGYLVEPSCP
                     EQIVKQIRLIFENLESANQRGIKARQRCVEKYSIEVMASKLAPLITNLL"
     misc_feature    complement(13485..13499)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.2"
                     /tool="antismash"
     misc_feature    complement(13516..13530)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.17"
                     /tool="antismash"
     gene            13921..14121
                     /locus_tag="NPUN_RS42630"
     CDS             13921..14121
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS42630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_041566681.1"
                     /transl_table=11
                     /translation="MLSHENRSYQPGIREVAFGIPVGVAKGIKGNYDARRAYGLSCSPR
                     QAAIAWKRIDYLWSLNSCQEA"
     gene            14124..14405
                     /locus_tag="NPUN_RS44625"
     CDS             14124..14405
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018815.4"
                     /locus_tag="NPUN_RS44625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1392 family protein"
                     /protein_id="WP_083782515.1"
                     /transl_table=11
                     /translation="MINQVPNLETCWYLSPPWGQTNSQFAIRNFRKGTKCMSQQFSITE
                     RTQALAIRIVKACSFLYEKPGVCRTLSKQLLRSGTAIQFATRFFALRS"
     gene            14557..14763
                     /locus_tag="NPUN_RS39840"
     CDS             14557..14763
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018815.4"
                     /locus_tag="NPUN_RS39840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1392 family protein"
                     /protein_id="WP_083782516.1"
                     /transl_table=11
                     /translation="MRIANCELRIVYGDRPPIRIVQGIQLINDCWFYSIEWISPAISEK
                     GDEVFTSRDSIARVTDYDLERVR"
     gene            14760..14981
                     /locus_tag="NPUN_RS43950"
                     /old_locus_tag="Npun_BF130"
     CDS             14760..14981
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="NPUN_RS43950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Npun_BF130"
                     /product="hypothetical protein"
                     /protein_id="WP_012413272.1"
                     /transl_table=11
                     /translation="MTIYTLYYRGEIRGEGISISLYPPHNWKGLHLPLFAPTPELLKWW
                     KASAQDAEAELEYERQFLLILHLPAAID"
     gene            complement(15452..15871)
                     /locus_tag="NPUN_RS35890"
                     /old_locus_tag="Npun_BR131"
     CDS             complement(15452..15871)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016869752.1"
                     /locus_tag="NPUN_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Npun_BR131"
                     /product="response regulator"
                     /protein_id="WP_012413273.1"
                     /transl_table=11
                     /translation="MGKIVLHKSRKCCNASKLILVCDDIFDNCFFLQTVLEIEGYQVET
                     VDSGAAALAFLESKRPALLLLDVMIPVMNGYEVVHHIKNNPLLESLPIVLITADEREFF
                     RKEIDVKVDGFIRKPVEPDVLIKYVQATLRQSPCL"
     misc_feature    16375..16393
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.97"
                     /tool="antismash"
     misc_feature    16839..16855
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.12"
                     /tool="antismash"
     misc_feature    complement(16923..16936)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.54"
                     /tool="antismash"
     misc_feature    complement(17426..17446)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.9"
                     /tool="antismash"
     misc_feature    complement(19249..19264)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
ORIGIN
        1 aacccagcaa tcgcatccat cagtttgggt tcgatgcgga agtttcagat taagcctatt
       61 gggagtaagt ctactgattt ttggctggaa cacgggagtt tactggtgat gcacccaggt
      121 tgccaatcaa cacatctgca tcaagttccc aaaactaaca aagtcgttag tacacggatt
      181 aatctgacat ttcgcccaca cattgggggc aaaagataat ggcattagtg ggacaacgaa
      241 agggatcggt ttgatgggac tgctgctttt aacagatgag gatatcttgt taactacctt
      301 gaacgattga gtcaatagag aatttaggat attgaccatc aacagaatct atacaattgt
      361 ctgacaattg ttatgcaatt gcaaggaaac ctcgatataa ttttagtaca tgagtactaa
      421 cagacgcgca gagcgtattt ttgaattatc tcagattttg gagagcctta tgccagaacg
      481 atatatgctt tcaatcactt tatcagaaaa ggcttacgaa gaatttcgtc ttgtagctac
      541 atggaagaaa attcctattg gtactttaat tagacagatt ttagaacgag aacatgaaag
      601 ccaagctttt ggagagctgg tcaaacgcgc aatggcagat ggacaattaa atgtttcaga
      661 agactaaagc ttacttgtat tgcacagata gcaattttat caacagtaaa aatcagagct
      721 agattccaaa tttcaaccat tacagaagga aattcaagat gcaattaaaa gaagaatttt
      781 atgaacacta caagaaaaat aatggatggg tatatctagt ccatgcggaa gggacactac
      841 gatttaagat tggtagatca ataaatccta ttggtcgatt atcccagcta cagggacaat
      901 caccttaccc attagttatt caagaatgca tttggacacc agatgcaatt tattatgaac
      961 agtatttaca tcaagaattt ggtaaatgta gagtttttgg tgagtggttt gagtttgtag
     1021 aaccttggga tttgtcaaat gcttataata aatttcgctg gtatggcagg acagatattt
     1081 ctgatatttc tgactgtata tttagttggt ttgtcaatag attttatgaa gtaaaaccat
     1141 tttgtcatct tgaagcattt actcaaatta attcaataat acaagaaact ttagctacat
     1201 cacaatgctt agatgactta gctgttacta tcgatttttt cttagaatat ctctttgaaa
     1261 cttggataac taaaaagttt aatatttgcc atatctacga cgaaactgaa cactttttag
     1321 attttgcctg tttttttaaa ggcttacgag agcgtactga ctgcttcatt tacggcttac
     1381 acagaggaaa aacttatgag tttatctaac aatacaaaaa cacttgaaag taggaaaaat
     1441 aacaagtatg ctgaaatact tggtagccca atagcatttc atcgagtcta cgccacaata
     1501 gctggtagtg ctagcgctgg gctttttttg agccaagcta tgtattggaa ttcgagaact
     1561 aatgatccac aaggatggtt ctacaagacc tatgaacaat ggacatcaga aacagcacta
     1621 aatcgctatg aattagacaa aattaggcat catcttacca ctatcaatat cttagaaacc
     1681 caattgaaag gctctccagc acgactttat tatcggatca accataaagt attgaataac
     1741 ttcttagatg ccattaaaaa aggctctttc acatccatta gaccaaagaa caagaataca
     1801 aaaaaatact ctcaaatctc tgagtctgtt gacagtcaac aaactggctc agtttgctta
     1861 ccctcaacaa acttgtctgc tgagggtcaa caagctagtc cgatgaccct caacaatccc
     1921 agttgctcac ggtcaacaaa ctctatatat atagaatcta cagagattac ttcaaagatt
     1981 acttcagaga ttacacacaa tgcgccccta gcttcgctac ccgcgccccc cacccaagag
     2041 agtgtgtgtg aaaaagaaga acttgattta acaacgaaag aaattgaact tgaagaacca
     2101 actccagaaa aaccaagttt agaagaatca actccagaag aaccaacccc acagcaaccc
     2161 acttcgttgt taaaaaattc cgagtctttg caacaaaccg ataacccctc cagaggatca
     2221 actattgcgg cggagtcgtt cgagaaatcc gaacaagcga ataagctgca actaacctgt
     2281 ccctacaaga cagcccagaa cgtgaaagaa ctgattgatg cctggctaac agacccgact
     2341 gctatgagtg atgattctct accactgctt gtcagagaaa caatcaagtg gaatcgctgg
     2401 gttttacctt ggcgcaatgg agagcgaaag ctaaataacc tctaccagaa cttcaaccct
     2461 gtagtcgtgg atttcctagc acaagaatta gccactaagt cgaaacgctc cgcacgacag
     2521 gaaatagatc atgcgatcgc agtaatgaac acctgggaga aaaccaaggg tgggtggacg
     2581 aacctgatgc agcgttatca ccaagcattg caaacagaaa aacagcccct acctcaacag
     2641 cgcactgctt tggctcacaa agtaaaaaat atcactagca gttcgctcga agatgccttg
     2701 gcacaagacc ggatacgacg tcagcaagag caatctattc aggttccatc caatgggtat
     2761 caacacagcc cacaaatgct ggaactaaaa gtaaagcttc aagccaaagc aaatgagcca
     2821 aaagttctga gcaacaccag accatcttcc acgaatttgc gagaagttga agcgcagtta
     2881 aaattagcac taagggcata attatgcact ctaatcaaga caacgtagtt tcttttcacc
     2941 ctgacaggtc acttgacaac ttacccccac aaaacatcga ggctgaagaa gcgattttgg
     3001 gtgggattat gcttgaccca gaagcaatga ctagagtcag cgatcgcttg agtattgaag
     3061 ccttttacat caacgcccat aaagatatct atcaagccgc agtccgactt catgctacat
     3121 accaacctac agatttacta agcgtcactg catggttagc tgaccacaat ttgctcaatc
     3181 gcattggtgg caggaataag ttagcaactc tggtagaccg cactgtatcc gccgttaaca
     3241 tcgacgcttt ggctgatctg gtgatggaga aatatcgacg gcggcagtta atcaaagtgg
     3301 gcaatgaaat tgtccaactc ggttacgaga cgcaaaccga actaccactt gttcttggac
     3361 aagccgaggc gaaagttttc actgtaaccc aaaatcaaag cgatgaacgc tctttggttt
     3421 tctcagcaca agacatgggc attgaacttt ttcaaaaact ggagatggga aacatggcag
     3481 gggagaaggt aggttggtac gacctcgaaa ctatcatcgg tggtatttat cccagcagtt
     3541 tagttgtagt ggctgctgaa tcccacatgg gcaaaaccca cttcatgatt tcttacgctt
     3601 acgaaatcat gaccaaactt ggaaagccag ttctgtatgt aactccagaa atggacaaga
     3661 atcaactcaa tgcccgaatg ctagcccgaa tcactggggt agacgcttct atgattcaaa
     3721 ccaatactca atgctactgg gagcaaatag cacagggtat aggacagatg gtggagttgc
     3781 cttggaaggt ttacgagcat tcctccccta caaccgcaat gattgcttct gctgtgcgcc
     3841 gtgccattgc cgaatttgat ggttctattg gtgctgtgtt tattgactac ttgcaacaga
     3901 ttcctctgga gtccggcggg aacatggcct ttgaagtcgg caagattacc cgccagattc
     3961 gggacattgc caaatctcac aaaatccctg ttttcttggg ctgtcaaatc aatcggggca
     4021 atcaaactac ggctgataaa cgccccaatc ggcatctatt acgtaattct ggtgaaatct
     4081 ttgaggtttg tgaccagtta atcatgctct atcgggatgc tgtctacaca aaagacccaa
     4141 gcgatcgcac tatcgagtta attgttgaga aaaaccgcct ttacggtaag ctcggcactg
     4201 cgaccatgtt gtgcgattta tcaacctcga aatttttgaa cttggcaaga taatttgatg
     4261 caatgaactt ttttaaagtt ttagaggtcg atatatgaaa gcgctatctg ttcgtcagcc
     4321 ttgggcatgg gcaataattt atgctctcaa aaatgttgaa aaccgtggct ggcccattca
     4381 ttatcgcggc gacattttga ttcacgccgc caaaacctgt accaaaaaag agtaccaagt
     4441 agcggaagaa tttggccatt gcatgggggt agtaatccca gagttaatct ctctccgtcg
     4501 cggtcaagtg attggcattg tcacaatagt agactgccaa ttttcacaag ttgcttctgg
     4561 ctgggggatg cctgggcagt accattggaa gctggagaat ccgcgcgaga ttacaccgat
     4621 tccttacatt ggtcaactgg ggatttttga agtgcctgat gatttggtga gagaagcgat
     4681 cgctcacaac cagatatgac cacaaacagc aacagtcctt atgcacttct ggttaagttg
     4741 aaccagtaat gtttatgtca actgcaatac ccgaaaaatt cttagaggat gaccttaaag
     4801 ctcaacaact tcgtagccaa ggatgcctct atcagtacat agaaaagaaa aagctacttg
     4861 atggctcaac cgctttttgc ccacgtatga ttggtgagcg tgacccagaa aatcctcaaa
     4921 gttggcgatg ggcctacaac tgggaaagag aaagtgggag ggatatggaa agggcgaagt
     4981 attggttcga ttccttgtgg tgccgttacc atgattcgct ctttgcagca gcagggagcg
     5041 gacagggagg atatcatcgc tttcatcaaa aaagcgaaaa ccaaaaatta ctccccaaaa
     5101 attttagatg tctgcaaaaa ttttaataac acaaatttta agccaacgct accagatgat
     5161 gccccgatcg cagtagtatt attcgcgggt ggcggcggca ttgaagcggg gatggtcgaa
     5221 gccggaattc gtccagtcat cgcggtggaa ttcgatccaa ctaaaccaga attgagccga
     5281 gcaatcgctc ttactcatca ctgcaacttc agcgagtatg gttgtagagt cgttcagcta
     5341 acagttcaag aagtagcgca gtcaggattc atagggtttc cccgttaccc cgactatctc
     5401 cacgcctccc cggtgtgcgc caactttagc cttgcccata cagcaaaagc gggcaagggc
     5461 attgaatcgg ctgacgacct gacagctgcg gcttctgttg ctgaagccat ccgacagttg
     5521 caaccacgag tgtttacgct agagaatgtc ccgcgctaag taggtcaacc taaaaaaacg
     5581 taagataaat agagtccact aattaagtaa gcagcaatgc caaaagtatt aaaaataata
     5641 cttaatagcg aagaagaccg tacacttaaa gaactaagtt gtgctgatgg agtagcacgt
     5701 cgaaccaagc aaagagcgac cgcattacgt ctcaatgctc atggatggaa tgtacctcag
     5761 attgcagagt atctagattg ggcacaacag acggtaagac aaacaattcg acgctgggaa
     5821 cttcaaggct tagggggttt gtgggaaaga cctggaaggg gaaagaaacg aagttggcat
     5881 gaagttgatt ggcaagtagt cgaaaaatgc ttaggacaaa atcgccgata cagtgctcgc
     5941 caactaagtc aaaagctttt agaggaacga caaattgagt taggtgccga acaaatacgg
     6001 cgactactca aaaaaagggg tggcattgga aacgtatccg ctactgtccg gctctaaatc
     6061 tcaagaaaga atatttacaa gctaaaaggc ttgattggga attacttaag ctctggtcac
     6121 aattagggtt agtttgttta aagtacttag atgaatctgg ttgctactgc actagcccca
     6181 ctgattacgc ttatggacgc aggggtgagc aaaaacgtat tcgacaaaat agacgacgtg
     6241 gtagacgtat caatatcttc ggtatttggg aaccaaaagt tcgttttgat tatgctttga
     6301 tggtgggaac tctcaaaaca ccaacctatg tccagctgat gaactggcaa gctcaaactg
     6361 ctgctactcg cttacttgaa actggacaaa tcaccgcgat cattcatgat aatgcctctg
     6421 tccataaaag ctctttggct tgccaacagc accaacgttg gcagcaacaa ggtttgtaca
     6481 tcttttttct tcctccctat agtccccaaa tgaatcggat tgaagatgaa tggttgcatc
     6541 tcaagcgtga cgagcttgct ggtcaagttt ttgaggatga atatgaatta gcgatcgcta
     6601 ttattgatgg tataaataac cgagctaacc acggacatta tcaagttgag cgttttacgt
     6661 ttaattaaat tgatctactt atcagaacag tcgaagtttc agtatcattc tgcaaacttt
     6721 ggaacttgaa ggatattcgg tcagttacag cgtcgtcaat atggcaggcg agataattgc
     6781 cccaggcgcg tcggcgggta gttctgattg caaacaaggg ttttcaggtt ggtttacctt
     6841 tgggaactac accttgtgat tggtacgaag cgttcacgaa gtgtgccgaa ggtatcgccc
     6901 atctcatccc cacgatgacc gattcccaac tactcctcaa acaacagcaa gctttggaga
     6961 aatttttagc cgggaatgcg cctacacctc tgttaattga aagagttgga gggcgcacag
     7021 agtccaagta taaacctgga catttaccct gcaataccat cttgcgatcg cctccggcgg
     7081 gcgggtacgc catcgcactt cacggatcac aagggttgca accggagcaa gttcgctgat
     7141 atctggttgc ctgatgggac agtcaaatct ttgacaatcc aaggtacagc cattttgcaa
     7201 ggttttccca gttggtatga gttcccaaaa gagactacta cggctgggtc aattatcggc
     7261 tattctgtac ctcccagttt tgccgcgcag ttatttactc acatacagaa acaattatca
     7321 ggagcatttt tatgacaaac caagagcaac tcacttaaaa tgtgttggta caggtaagga
     7381 agaggacaac caacaagcag gggacagaaa agaagaagca cagaggttgt gcggtgggag
     7441 cgaatttccg cctgccttaa tggttttctt tccttagcga cagtttacat ctgggttcgc
     7501 agaattttat tcgtgggata gattcatagc tgccttcagc aagaactgcc ctctgccttt
     7561 ctcaataagt tatctcaaaa agattaaggg taagtaattc ggattaacga ccaacagttt
     7621 taaaatcatt ttagttaaaa tgccctaatt aaagtgccta gagttggcgt acctaaaact
     7681 gaagaggcta aattccctgg gatattccca tcaattatcc agcagtcaat ccctaagtta
     7741 gaaatagtca aaaactcctc aactttctta gccatcccgc cagtaacatc tactgatttg
     7801 ctcttgccca agaaaggttt aatctgagaa tagttagctt gagtaatatt ggaaactact
     7861 tgcccatctc gatcatcaga aatgttgaat gctgatacaa aagtttacat atctagttac
     7921 actaactcta aaaagcctaa aatagtcaac atgacatcat ctcttcaaac caatgaacat
     7981 aacttatttt ctgacacata caagattgta aatagcggaa tttatctaat agcgtatgtc
     8041 cccattgttg tggtacagat aatatctgta aaattagata agctattaaa gtaacgtaaa
     8101 tttgtatggt gataccatta acatttttag taattaactt gtcaagtttt aagtgcattt
     8161 tcaaaaactt ccacaacaat tcaactcccc aacgcaatcg ataaatatcc ctgatttcat
     8221 aatcactaac ggcagcctct cctaatgttg gtaaattggt tactaatcga aactcagttt
     8281 tcgtttctaa atcacaaaaa ttaatcactc tataggcttg agcatcatta gatgcaccaa
     8341 ctttaattaa tccagtttgc tcctcaaatt ctaacttcca attgtttttt acccgcaaaa
     8401 caaagtattt gttttcttgg actaattctt ggataaattt taatccagca aaacctctat
     8461 ccattacacc aacagcatta tttggtagac tagacatcat tttacaacca aatttatagt
     8521 catggtcatg tccaaagttt atgaagttat ctgatggact tccagtagct aaatttagag
     8581 aactgaaaag ttttacttga tggtgtccta gtacccataa caatttactt gtgagagtaa
     8641 taattgttga atctattgga caaattgcat atttatcatg taactttttt tgaactttct
     8701 tctgtactaa ttcatttaat ttttggtaaa tttcttgaaa aggtttttga cttcgatgta
     8761 agtttgcttt agagaaagta gaaatatcta ccggaaatcc tgtgttgttt aatctgttaa
     8821 ataaatctcg catacttgtt aagctgttat ccatagcata agataaccag cactcaaaga
     8881 acagacgact gttcaatact ggataatcgt tttttggcag tcctctcaag atatctttga
     8941 caatcttggg aaatgaattt ataatcacta ttaaatagat atactttaat cttccgccca
     9001 aaatttaaca tattttgggc tgtttttatc ggatttttct taacattcaa cacttttgct
     9061 cgatcatata cacctgcata attcccaaca tttattagtc taactttaaa cttaccttga
     9121 agatagaagt atttcgctag ttctgcaagc attgcatctg tcgaaaagac agtaccacca
     9181 atagcttgat ctagaacgac atcaccgaaa actaaaggaa ttaaacctgc ttgtagactg
     9241 ctttctatcc cactaaagtc actcttcaat agttttttgt tgtgagtaat tatcatacta
     9301 ataggtggca aacttaccac tggtaaacct acttgtaaaa aacttttagc tagtaggaaa
     9361 tttaaatcta aagcatcttg gtggactaag cagaacccta gtttttcttc atcacctgaa
     9421 aaaccgttaa ttgtattata tttattcgct gattggtggg cgaaagaacc agcaccgtta
     9481 ccaataatca gtttcagatt aggattttca cgtttgatta ggctcacttg ctcaaccagt
     9541 tgtgttataa cttctcttcg agcagtataa ggtttatcct tgtcagtaat taaggagcct
     9601 cctagcttca ctaatactaa ttccataatc aaatattaaa tgagggaaga caaaaactta
     9661 taaaaaacta atcctagaca aaaaaaatca aaattgctaa taatttcaac acaatttaac
     9721 aaaatgcatg aaagtaaaca gtaaattttg gttacaaaat aatgcagaat ttatcgacca
     9781 gaatacatat gtcagtcgtc agaaaacagg tatgaattct gtacgacaca acgactgcag
     9841 tcagtgcatc actgaagaat gaataagggg gtttaagacc cccacaaaac tagaattttt
     9901 ggtggtctag ttgaaatgta ggcgatcgct attactccta cgcttgttag cagcagtttt
     9961 ggagtattac tatataccat gttcctaaag ttattttcca ctactgccgg gttagtgcgt
    10021 gattaagctt ttttttctcg aagcttttta tcttcatagc aatcatcccc gcatatatta
    10081 gatcaaaaac aaaaatcgca gtatataaaa atataaataa aagtgatcta ccttgtgttg
    10141 gatgattaat ataaaaacca atggaagcca gcaaagttcc tatcattttg aagatagcaa
    10201 taaagattga ttgacctcgg acagtattac gtttggtcaa catatcaata aagagaatag
    10261 acatgagaag attttgccca aaagctgtat acgcaccgct ccaatcttga aattcatctg
    10321 tgattaacag gacacagcaa aagctagtaa ataaagttaa tataaacact ggataaaata
    10381 atttatttgg tatgtccttc aactcagatt gcccaaactt gaaaaatcca tacaagataa
    10441 ttaaatcaag catcaaccac acaatattga tttgaagttg tggtggctga tgaggatgaa
    10501 taaaagaaaa tataaattcc caggaaagat tggcacacaa cgcaaccaat ggcattccat
    10561 acgtttgatc tttaaagcca cgttgaatca acaaaatata agtcagtatc caaaatgctc
    10621 cgctgccaag cattaaataa gttcccataa atcattacct cctttatgct ttttaaaaat
    10681 ccaaattctt acgggctgta atacaattat tcctcttata caaagtaaat aatgcactgc
    10741 atgtctaata caaagttact gagcatgagt gttaactcta gttaaccgcc tgtgcaatga
    10801 aaaactgccc tagggcaagg agtccagagc agtgcttgta aaaaaaatta aatatgggag
    10861 ttttaaactg ttgcccccct ctttacatct aatttgttcg ctatgtaata ctcttcagtt
    10921 caagttttgt actttatgca aaaagagcga aaaactgtga aatcttcact atacaagggt
    10981 taggcgcaat aaaccaagct caatacaaca cccttggctg aatacgtaca accaatggtt
    11041 atcaaaattt ggtcaaacat aaatgcacca ttaccccaaa aaacaatcgc aggctgtgga
    11101 ggggcgattg taacaagggc acaggagagg cgattgctta cgatagatgc actttcacaa
    11161 aaatactcta ccgatttatt cacatcaata gagtatataa atttactata atcatctttt
    11221 accaacattc agtttatgac ttagtaatta tttatacccc tgtataaata ctgcaaatct
    11281 tgcctatagt ttacgtgggg tttcccttgc gtcggcacgg caactcacaa ccgaacacta
    11341 aaaaaaacct atgtttcgac tcggtgagtt ggtcgagttt cgattttacg gtgatgggtc
    11401 atcgattcag attgtccagc gaatttttaa gctatgcagg caataactaa ggctctattc
    11461 cttcatcaat ccaagcatca attgctgttt ttacctctaa ttcagtcacg gcagaccatt
    11521 ctctttcgtt gatagttgtt ttaaataccg ctcttttacc gtaaccaact ttttccattg
    11581 agtgtccgcg atacacattt ttaggcttaa tcatttttct taatcatatt tagagaatat
    11641 tataaacttt cgctcaataa gaagagtagt ttgattttct atgatggctg ctgattgagg
    11701 agattatcat aactgtagtg ttaggcttgt agtgaggaca tgacatcagc ctagaggaga
    11761 ttagtaatta acggtgcgag tttagaagcc ataacctcta tactatattt ttctacacat
    11821 ctttgtctgg ctttaatacc tcgctggttt gctgattcta aattctcaaa tattaatcga
    11881 atttgtttaa caatttgttc aggacaagaa ggctcaacta aataaccagt atcacctaaa
    11941 atttcgggaa tatctccaac acgtgttgat aatacaggtt tagccattgc cattccatca
    12001 gtcaacttca aaggaaattg agcgcgagtt tctggagtat ctcgctgggg aacgacaaca
    12061 atatgagcag cagcaactag atccggcatg gcatcaactg gatactttgg tagtttgata
    12121 atccagcgtc cccaacgttg ttgaagttgt tgatcgtaat catcataagg actgccacca
    12181 ataatcacta attttaagtc tggctgatta attttttcta acgctataag aacatcttct
    12241 aaacctttat aaggtctagg tgcaccagga aacattaaaa ttcggtattc agataaatta
    12301 tagcgacttc tactagaatc aggattacat tgagccggat caaataaaga ggtatccttg
    12361 ccattaggaa ccaacatacc accaaaacgc tgctgcaaaa atttagtatg caccgtcaca
    12421 gcatccgcat gatttactaa accttccatc catttaacgt acaaaggatg atatgggctc
    12481 ctgagtgcgc cgtctgattt caataaatcc ctagctaatt gtttcagtgt cggacaataa
    12541 cgccagttgt caccaccatg ccagctaagt tcccaatcat ctatgtctaa aatcactggt
    12601 tttctgctgt ataaactttt taacagtgca actccgaaac tcgctatctg tggtttaatt
    12661 gcataaatta tatctccatc aatatgtttt aaaactttgt tgactgctgg aaaaaatttc
    12721 ggataatttc caccttctat agcaaaaagt ttcgtatcag atggaatggc agcagagaga
    12781 tttttgttaa ataaaaatcc taatatttct gtttcataac ccaatttttc taacgctgat
    12841 ttcaataacg atgctcgaat gaaaccatca ttagtagaca aattccatac aagcagcgat
    12901 atctttagtt tagttttcat ttcgataaca tttgataatt atgatttaag aaaaaactgc
    12961 caaatcaaaa acctacatta cttattgtaa atatttcagg aattagctga ataatttata
    13021 gctaaaagta cttttttaat ctttcaataa atcaatcttt ttactgtatt tacgatgaaa
    13081 tttcagtaat tctatataag ctaatggtac tactatgggc caaaaaaata gttattaata
    13141 ctaaaattat tccagataaa aagtactgct ttcggctcat gtctttatca tctatcaaga
    13201 aaaataacca ttgattcaac aaataccaag caaatactaa ataaacggtt attccgatat
    13261 atattagaag taaattcaat actaaacctc tattaatagt aaagtttgag tcagcattag
    13321 aaatagaaaa aatatttttt tgaatatcta attaaaaaac taattgattt ttataaaagc
    13381 ctaaccttta ttttataaat tttactcttt ggccataaac ctctgaattc gtgtgaatgt
    13441 tagaaatttt tataaaatag ataatctaaa tattgtgaaa ctaaaatttt cacaataata
    13501 tctcttaaaa tttaaaattt acagaatata agctgcgatt gcaatgaata atcctttgat
    13561 taacttgtca attttttatt agtgctggat agtttgcctt ttttgcttaa cttcgacaaa
    13621 ctccaagtcc agtaagctgt ctaactcgga tttctcacca cacctctcaa agcctgtgct
    13681 tgtgcagggg agagttcaaa tactaagttc cttcccctct gcccctctgc tctatcaaac
    13741 gcctgaagct tgtgagaaat gcgggtctag atatctccta gtcacaatca cgactttgct
    13801 acgaataacc agaaatccca atccacacag atatcgccaa gtaccactgc catcggcaac
    13861 aatccaacat catctgcggc ggatttcttt gcctcggcac aactaactca ggcaataaac
    13921 ttgctctctc atgaaaaccg aagctatcaa cccggcattc gtgaggtggc ttttgggatt
    13981 cccgttggag tagccaaggg gatcaagggt aattatgatg cccgtcgtgc ttatggtttg
    14041 agttgttctc cccggcaagc tgcgatcgct tggaaacgga ttgattattt gtggagtcta
    14101 aactcctgtc aggaggcata agcatgatta accaagtccc gaatctagaa acttgttggt
    14161 atctttcacc tccttggggt caaaccaatt cgcaattcgc aattcgcaat tttaggaaag
    14221 gaactaaatg tatgagtcaa caatttagca ttactgagag aacgcaagct ttggcaataa
    14281 gaatagttaa agcttgtagt ttcttatatg aaaaacctgg agtttgtcga acattatcga
    14341 agcaattact acgaagtgga acagctatcc aattcgcaac tcgctttttc gcccttcgca
    14401 gttaagtcag caatgatttt aagcttatat caatttaaag atagtgagta tttaattaaa
    14461 ttggaattga taaaccaact gaacattaaa ttgcttgcaa taagtatttt gtattttaca
    14521 attgcgaatt gtgaattgtg aattgcgaat tgcgaattgc gaattgcgaa ttgcgaattg
    14581 cgaattgttt atggtgatag gccaccgatt cgtattgtcc agggcattca actgattaac
    14641 gattgctggt tttacagtat cgaatggata tcacctgcta tatcggaaaa aggtgacgag
    14701 gtttttacat ccagagattc cattgcacgg gtaactgatt acgatttgga gcgtgtgcga
    14761 tgacaatcta taccttatat tatcgtggcg aaatccgagg tgaggggatc tccatctcac
    14821 tttatcctcc acacaattgg aagggtttgc acctgcctct ctttgcccca actccagaac
    14881 tgctcaagtg gtggaaagcc tctgcccagg atgctgaagc tgaacttgag tacgagcgcc
    14941 agtttctgct gattcttcac ctcccggcgg caattgattg atctttgggt aagaaagcag
    15001 cgcaactcag acgcagatat tacgctgtgc tgcgcgtgaa aaaaccgaag acttttgcca
    15061 tcgccacatc gtcgggcagg gggtggtact gcgtgatctg ccagagttat ggggtggtga
    15121 agttgcagca gctaatcaaa tgtccacaaa ttgtagacaa aataagggta acgagttagt
    15181 tgatttacga actataaagc caaaatgaat actactgtga acatctactc atgattgact
    15241 ttcaaatgga atcgatagca gatatcaagt agcttatctg taaaagcctc aattgaaaga
    15301 ccttgtacgc gcctttgtac ggtatcgcac agaattctta gtccgaatgt gtgtaatata
    15361 gaaacagtca cctataaagt ccgagagatt ttaagccgta actcttaaat atttcctcac
    15421 aaatgctagc tacttcattg atacattagg gttataaaca aggcgattgc cgtaaggttg
    15481 cttgaacata ttttattaat acatccggct caacaggctt tcggataaat ccatccacct
    15541 tcacatcaat ttctttccga aaaaattccc tttcatcagc tgtgatcaat acaataggta
    15601 gagattctaa aagaggatta tttttaatgt ggtgaactac ttcgtaccca ttcataacag
    15661 gtatcattac atccagtaga agtagagcag gtcttttaga ttctaaaaaa gcaagtgctg
    15721 ctgctcccga atcgacagtt tcaacttgat aaccctctat ttctaagact gtttgaagga
    15781 aaaagcagtt atcaaaaata tcatcacaaa ctagaatcag cttactagca ttacagcact
    15841 tccggctctt atgaagcaca attttaccca tatccctttt ctatcctaac ttttgagact
    15901 gtgtgcgtac ctcataacag acgcaagtgc tgtatcttgc ttgacttcct ttttcatttc
    15961 catgtttaaa taaagactaa accattgttt aatcacttgt agctaaatac ataattcttt
    16021 tcgtcttacc ttggtattag ttactacata agaatctgca taagtattta tcaggaaagt
    16081 cgggggcagt tcttaatagg ggctcagttg ggaatactgc acttttgcta tgctcagtgc
    16141 aaactttctg ctctctgccg cgatcgctag cgaacttgcg gtttaaaacc cccacaaaac
    16201 tggaattttt ggtggctctg gttaatacca attcacaata caactcttgg agaggctatg
    16261 cttagggcgt agctatgccg caggctttac ggctgcgccc ttctcctgtc gcagacgcta
    16321 tgcgtagctt gcttccacaa agtggtacga ctacgctcac gctgaactca gtacaaggag
    16381 atcaattcgc aataggctac gcctataggt agataaatta aaaattttct ctcttgttta
    16441 gtatttatta ttacgtccct tcgtttacat ataattcgtt tggtatgtaa tattcttcag
    16501 ctaaagtttt gtactttatg caaaaagaac tataaacgaa tggcactaag ttaaacgtaa
    16561 accctacccc caacaagata gccctgacaa gttttcttag tgacattcaa ctataaacct
    16621 tgaaaactgt atcctataag gattagagac aataaaccaa gcccaacaca atcctatcag
    16681 ttgtatgcgt gtaaaccaat ggttatcaaa atctggtcaa gcgttgcacc attaccccaa
    16741 ggaagcaatc gtaggctgtg gagagcggtt gtggcaaggg caaaggtgaa ggcgatcgca
    16801 tgaaggaact gggcaaaagc tcaatcacca caggcacttt gtaactttgt aacttgtcgc
    16861 agacatcact tcctaaacac ttggctcaag tggctcgccc gctcattgct aacatggcca
    16921 ggatgatctg gttcaattgc cgcattgttg tagcgtttat ctgcggtagc aagcattgta
    16981 agagtgataa gatgtctggc atgggtggct tgcagttttt gagttgtcgt tgtgagagac
    17041 aataactcta ctacgaagcg ccctacctct tcatgctctt attttggcta aggtattgtt
    17101 agaagaacca caaaggacgc acaggaagag aaaaaaagag aaattgaaaa attgattcat
    17161 acctaaaatt tttattgaca gactaatacc atgactagga gcgagcgtaa tgagtatcca
    17221 gcatcatctg ttttcctatg aatttgtact cttaacagta aaatttacgg attttttctc
    17281 gcctagattt aacattgaga taagtatccc tttacccctt aacttttttc ccacttctgc
    17341 aagaagtcta atatactttt taatctttac atagtttttt cataaacata tcttaacatt
    17401 ttgccaatat cattagctat ctagttattt atcaagttga caataagccc aaaaaatatt
    17461 tagcagtaaa ccaaatacca aatataggat ttacgcacta gataaatgga atatttgatg
    17521 aattaactaa tattagttgt ttcagatttt tgggaactac ttttaaatga gtggtaattg
    17581 gacgtgttac tcattgaatg ttttccttgc ttatgctgcg acaaatcgaa ggttagttaa
    17641 tatctaaaat tcctactgta tatctagtga gttctgtcca tgcgtaattc ttaagtgact
    17701 agataataac tagatttaga tatttacttc caaattcaga ggaatttatg gcatctacaa
    17761 ccatttttac tcctggcaat ctattggtta gccgtagtgt atatactggc acggcttcaa
    17821 cagtaacttt tcctgggaca ttgccaaacg gagtagcgtc agttgctgat ggcacatatc
    17881 cgaatgtatt ttcaaacgaa agcgtagatg gtagttttgg tgtaacttcg ccgatttttc
    17941 tcgatcaagt tacgccctct gggacattag tcaactttga aaatgtgacg cagacagtaa
    18001 gcaaccagct tgggaaaaac ttgtctacca gcttcccatc taagtcagag ttagcactga
    18061 acttaactcc agatggtacg ggtgttacat tcgtgtcata tctagctgca tcaaacacac
    18121 tagacgtatc aaactcgaac acacccggac acgtagacaa tactaacccc gtatcaagcg
    18181 tcggcacaat tcaacgtgca attactcaaa ttgatagcaa tggtaacgtt gtcgatctaa
    18241 ctccaatcaa tgcctatagc ggaaataacg gtcgcgctgg tcttttgggt agtaatggtc
    18301 tttactatac agtaggaaat gctggcaatg gaggtagtat ttctattgct ggagcgacca
    18361 ctactgaagg cagcacaacg atcgggacta ccgatatcac tggtttggtt gtaggacaag
    18421 cgatcgccgg aagcaatatt cccgcaactg atgccaatgg tgttcctgtg actgtggttt
    18481 ctactgaccc aaccactaat actttcgtca ttagtgcgcc ggctacagtt accggtgtcg
    18541 atgccaaagc aaagattatc caaacaggta ctacactatc tgatttaagc gccaacactg
    18601 gtgtacaagc aatccaacct ggagatacaa caggtaatac aactgtagtt gggatagaaa
    18661 aaggctctgt aggatctacc actggtaatc agtatggttt ctcaatcact gatttaccag
    18721 gtattaccac tggggataaa acaggtaaag acgacaactt ccgtggtctg acactgaacc
    18781 cctatgataa ctccctttac gtctccaaag gcagtggtag taatggagtc aacactgtct
    18841 acaaagtgac tccaactagc ggtactcttc ctacccttga caatgcgagt actgctagca
    18901 tcactatttt gcctggtttc ccaacggatt tagcaaatgg ttcgaccaac ttctatccct
    18961 ttgggctgtg gtttgccaat ccgacaacct tgtatgttgc tgatgaaggc gctggaatca
    19021 aaaatgagaa atcagctgcc gatctgcttc tagctgcaaa cgatgctaat gctggtttgt
    19081 caaagtggag tttggctaat ggcacatggc atctagacta cactttacaa aatggcttga
    19141 atcttggtca agattacagt tctagcgttg ctgatgggcc taacggagaa atttattctg
    19201 ctccaactgc tactgctggt cttcgtaaca ttacaggtca agttaatggt gacggaactg
    19261 tgacaattta tggtgtaact tcaacagtta gcacccaaac cgatcagggt gcagacccaa
    19321 ataaagttgt ggcaattact gatctggtgt cagcgacgaa tttacccata accgaaagct
    19381 ttaacacagt agagtcagcc aaatacggtg aagtccttcg cggtgtttcc ttcacaccct
    19441 cgtcaacacc tgtttctcca ccagttgttt ctacccaacc tccggcaagt cctaccttta
    19501 atcatgttct aattatttcc attgatggat tacacaactc tgacctctca gttgctaatc
    19561 tgcaatcttc tttaagcaat atcaagcgtt tgcaaggcga aggtgttacc tacaccaatg
    19621 ctttcacctc tgcaccctct gactccttcc ctggcgaact aaactatatc actggtgcga
    19681 atcctggcac gactggtgta ttttatgaca aatcctacag tcgcaccttg tatgctccag
    19741 gtactactgc tgctgaaatc gccgccggta ctgctaaacc gggtactggt gtggaatttg
    19801 ccgaaaacgt tgatgcatct tgggctgctg gtggtacttt agatggtggt caagggtttg
    19861 ataccagtca actgcctgtt gatagcaatg gcaaccctgt ttatcccaac caatacctca
    19921 aggtcaatac aatttttgat gtggctaacg cggctggact gagtactgct tggtctgaca
    19981 agcatcccgc agcttataca attcttgctg gaccgtcttc agatcccacg cagtttaatt
    20041 ttgctacggg aaaggttggt agtatcgacg attactcttc cctagaaatt aatgccgcag
    20101 tagcgatcga tccaactaag cccggtactc tcccaactag cacgggtgct ttagtcgatc
    20161 agtcaacagg gactccttac tccaatacca accctgatat tacatccaat ttctttaacg
    20221 acgcgacaaa gggtaatccg gctctgttta aggctccacc cactggtttt agcgcgaatc
    20281 agttcaccag tgtggcaaca acctccgcct acgacgatct caaggttaag caaatactca
    20341 acgagatcga tggctttaac gctgcgggga cgacaaaagt tgacactcca gcaatttttg
    20401 gcttgaattt acaagctgtg agtgtagccg agaaagagcc agctactcaa tttaacggtg
    20461 gcgggattga cgctaatgga aatgctcgtc ccgatctggt aacggcaatc gatcataccg
    20521 atcagagcat tggtctgatt ttggatgaat tacaaaagca aggattggac agttcaactc
    20581 tggtggtttt aaccgccaag cacggacaaa acccagtcca agatcctacc gttggtttga
    20641 atagtaca
//
