LOCUS       NC_010612              20933 bp    DNA     circular CON 17-DEC-2024
DEFINITION  Mycobacterium marinum M, complete sequence.
ACCESSION   NC_010612
VERSION     NC_010612.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium marinum M
  ORGANISM  Mycobacterium marinum M
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
REFERENCE   1  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Davies,J.K.,
            Johnson,P.D., Abdellah,Z., Arrowsmith,C., Chillingworth,T.,
            Churcher,C., Clarke,K., Cronin,A., Davis,P., Goodhead,I.,
            Holroyd,N., Jagels,K., Lord,A., Moule,S., Mungall,K.,
            Norbertczak,H., Quail,M.A., Rabbinowitsch,E., Walker,D., White,B.,
            Whitehead,S., Small,P.L., Brosch,R., Ramakrishnan,L.,
            Fischbach,M.A., Parkhill,J. and Cole,S.T.
  TITLE     Insights from the complete genome sequence of Mycobacterium marinum
            on the evolution of Mycobacterium tuberculosis
  JOURNAL   Genome Res 18 (5), 729-741 (2008)
   PUBMED   18403782
REFERENCE   2  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Pidot,S.J.,
            Davies,J.K., Small,P.L.C., Johnson,P.D.R., Brosch,R., Cole,S.T.,
            Ramakrishnan,L. and Parkhill,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2007) Pathogen Sequencing Unit, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000018345.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,598
            CDSs (total)                      :: 5,546
            Genes (coding)                    :: 5,407
            CDSs (with protein)               :: 5,407
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 53 of 139
            Pseudo Genes (incomplete)         :: 113 of 139
            Pseudo Genes (internal stop)      :: 14 of 139
            Pseudo Genes (multiple problems)  :: 34 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6164029
            Orig. end                         :: 6184962
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000854.1.
            DNA and bacteria are available from Dr Lalita Ramakrishnan,
            lalitar@u.washington.edu.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20933
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="32"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20933
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20933
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10933](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10933)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            38..1513
                     /gene="radA"
                     /locus_tag="MMAR_RS25505"
                     /old_locus_tag="MMAR_5085"
     CDS             38..1513
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="radA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396606.1"
                     /locus_tag="MMAR_RS25505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5085"
                     /product="DNA repair protein RadA"
                     /protein_id="WP_012396606.1"
                     /transl_table=11
                     /translation="MANARLQYRCADCRYLTAKWVGRCPECSSWGTVEEVSVLSAVGGG
                     SRLGRRAHGPAVPTSQAVPISSVQPNLSRHRPTGIDELDRVLGGGVVPGSVTLLAGEPG
                     VGKSTLLLEVAHRWAQSGQRVLYISGEESAGQIRLRADRIGCGGPAAPDISEVSAIDNS
                     AEIYLAAESDLHAVLDHIDTVGSALVIVDSVQTMSTSEVDGVTGGVTQVRAVTAALTAA
                     AKSNGFALILVGHVTKDGAIAGPRSLEHLVDVVLHFEGDRNGGLRMVRGVKNRFGAADE
                     VGCFLLHDNGIEGVADPSNLFLDQRPTPVPGTAITVTLDGKRPLIGEVQALLATPNGGA
                     PRRAVSGIDHARAAMISAVLEKHARLSLAVNDMYLSTVGGMRLTDPSSDLAVAIALASA
                     YANLPLPTTAVMIGEVGLAGDLRRVNGMDRRLAEAARQGFNIALVPPGCEAVPAGLRTL
                     CAPTIVAALEHMIDIADHRSVPSAKVHRLDTSH"
     misc_feature    42..55
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.48"
                     /tool="antismash"
     gene            1532..2608
                     /gene="disA"
                     /locus_tag="MMAR_RS25510"
                     /old_locus_tag="MMAR_5086"
     CDS             1532..2608
                     /EC_number="2.7.7.85"
                     /codon_start=1
                     /gene="disA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_218103.1"
                     /locus_tag="MMAR_RS25510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5086"
                     /product="DNA integrity scanning diadenylate cyclase DisA"
                     /protein_id="WP_012396607.1"
                     /transl_table=11
                     /translation="MHAVNRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDEN
                     VEAICDGGFPLDVRYAPTRLRELCKMDGAVVLSTDGSRFIRANVQLVPDPSIPTDESGT
                     RHRSAERAAIQTGYPVISVSHSMNIVTVYVGGERHVLSDSATILSHANQAIATLERYKT
                     RLDEVSRQLSRAEIEDFVTLRDVMTVVQRLELVRRIGIEIDNDVVELGTDGRQLRLQLE
                     ELLGDNETARELIVRDYYANHEPLATAQITATLDELDAITDTELLDFNALAKIFGYPST
                     TEAQDSALSPRGYRAMSGIPRLQFSHTDLLVRAFGSLQGLLAASASDLQSVEGIGATWA
                     PHVREGLSQLAESTIADQ"
     misc_feature    1724..1726
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2620..3417)
                     /locus_tag="MMAR_RS25515"
                     /old_locus_tag="MMAR_5087"
     CDS             complement(2620..3417)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_218104.1"
                     /locus_tag="MMAR_RS25515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5087"
                     /product="hypothetical protein"
                     /protein_id="WP_085979928.1"
                     /transl_table=11
                     /translation="MLDLEPRGPLPTEIYWRRRGLALGIAVVVIGVAVAAVIAFVGSNA
                     GAKPANADKPAGAQDHPGSSAPQAPQPAGQTEGNAPGAPPQGQNPETPTPTAAVQPPPV
                     LKEGDDCPDSTLAVKGLTNAPQYYIGDQPKFTMVVTNIGLVACKRDVGAAVLAAYVYSL
                     DNKRLWSNLDCAPSNETLVKTFAPGEQVTTAVTWTGMGSAPKCPLPRPAIGPGTYNLVV
                     QLGNLRSQPVPFILNPAPQPPGPLPAPGPALAPPPEAPPAQGG"
     misc_feature    complement(2680..2682)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3531..4148)
                     /locus_tag="MMAR_RS25520"
                     /old_locus_tag="MMAR_5088"
     CDS             complement(3531..4148)
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011741806.1"
                     /locus_tag="MMAR_RS25520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5088"
                     /product="carbonic anhydrase"
                     /protein_id="WP_036426185.1"
                     /transl_table=11
                     /translation="MPNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPT
                     AVIFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVPLVVVLGH
                     DSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMGRRDGLKRVDEFEQRHIQETVAQ
                     LMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLRDHVGDIGA"
     gene            4147..5058
                     /locus_tag="MMAR_RS25525"
                     /old_locus_tag="MMAR_5089"
     CDS             4147..5058
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006338328.1"
                     /locus_tag="MMAR_RS25525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5089"
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="WP_036450612.1"
                     /transl_table=11
                     /translation="MPAIVPQPSMTCPEHIPATNLVAWYERCCRDLPWRAPDVSPWQIL
                     VSEFMLQQTPVSRVLSIWPDWVRRWPTASATATATAADVLRAWGKLGYPRRAKRLHECA
                     MVVAGDHDDVVPDDVDTLLTLPGVGSYTARAVACFAYRQRVPVVDTNVRRVVARAVHGR
                     AEAGSPSATRDHAEVSALLPDDELAPRFSVALMELGATVCTARAPRCGQCPLAECAWRR
                     AGYPPATGPARRVQTYAGTDRQVRGRLLDVLRDNNGPVTRAQLDVAWLTDTAQRDRALY
                     SLLADGLVTQTADGLFALAGEA"
     gene            complement(5066..5833)
                     /locus_tag="MMAR_RS25530"
                     /old_locus_tag="MMAR_5090"
     CDS             complement(5066..5833)
                     /NRPS_PKS="Domain: Abhydrolase_1 (14-237). E-value:
                     9.7e-13. Score: 40.2. Matches aSDomain:
                     nrpspksdomains_MMAR_RS25530_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785694.1"
                     /locus_tag="MMAR_RS25530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5090"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_012396611.1"
                     /sec_met_domain="PF00561 (E-value: 3.5e-06, bitscore: 25.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-14, bitscore:
                     53.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTDLLTYHGGEGEPLVLVHGLMGRGSTWSRQLPWLTRLGAVYTY
                     DAPWHRGRDVDDPYPISTERFVADLGEAVAELGGPARLVGHSMGALHSWCLAAERPGLV
                     SALVVEDMAPDFVGRTTGPWEPWLHALPVEFDSADQVFAEFGPLAGQYFLEAFDRTATG
                     WRLHGHTSRWIQIAAEWGTRDYWAQWRAVRQPALLIEAGNSVTPPGQMLAMAEVDRSTK
                     YLHVPEAGHLVHDEAQLAYRQAVEAFLAAERVR"
     aSDomain        complement(5123..5791)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS25530_Abhydrolase_1.1"
                     /evalue="9.70E-13"
                     /label="MMAR_RS25530_Abhydrolase_1.1"
                     /locus_tag="MMAR_RS25530"
                     /protein_end="237"
                     /protein_start="14"
                     /score="40.2"
                     /tool="antismash"
                     /translation="PLVLVHGLMGRGSTWSRQLPWLTRLGAVYTYDAPWHRGRDVDDPY
                     PISTERFVADLGEAVAELGGPARLVGHSMGALHSWCLAAERPGLVSALVVEDMAPDFVG
                     RTTGPWEPWLHALPVEFDSADQVFAEFGPLAGQYFLEAFDRTATGWRLHGHTSRWIQIA
                     AEWGTRDYWAQWRAVRQPALLIEAGNSVTPPGQMLAMAEVDRSTKYLHVPEAGHLVHDE
                     A"
     CDS_motif       complement(5561..5599)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MMAR_RS25530_0001"
                     /evalue="4.80E-04"
                     /label="NRPS-te1"
                     /locus_tag="MMAR_RS25530"
                     /protein_end="91"
                     /protein_start="78"
                     /score="12.7"
                     /tool="antismash"
                     /translation="GPARLVGHSMGAL"
     gene            5889..6206
                     /gene="mhuD"
                     /locus_tag="MMAR_RS25535"
                     /old_locus_tag="MMAR_5091"
     CDS             5889..6206
                     /codon_start=1
                     /gene="mhuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396612.1"
                     /locus_tag="MMAR_RS25535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5091"
                     /product="mycobilin-forming heme oxygenase MhuD"
                     /protein_id="WP_012396612.1"
                     /transl_table=11
                     /translation="MPVVKINAISVPAGAGPELEKRFAHRAHAVDNSPGFLGFQLLRPV
                     KGEDRYFVVTHWESDEAFQAWANGPAKEAHAGERANPVSTGASLLEFEVVLDVAGNTPA
                     D"
     misc_feature    complement(5910..5923)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            6181..7551
                     /locus_tag="MMAR_RS25540"
                     /old_locus_tag="MMAR_5092"
     CDS             6181..7551
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015357444.1"
                     /locus_tag="MMAR_RS25540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5092"
                     /product="serine hydrolase"
                     /protein_id="WP_012396613.1"
                     /transl_table=11
                     /translation="MQGTRRLTSRRRNRLRRATVLTAAAAMVLTLTPGCSSSPTPSANA
                     ANPQRRIDTVTPPGLRAQQTMDMLNSDWPIGPAGVATLAAPSKVDSVEATMEGLWWDRP
                     FALDSVDISASVATLHLTSSYGARQDIRLHTDDGGWVDRFELETLPPPTITAWRDVDAV
                     LSKTGARYSYQVSKVEKGQCTRVAGTNTNQPLPLASIFKLYVLHALADAIKSGTASWDD
                     QLTVTAKSKAVGSSGLELSPGDHVSVRRAAEKMIANSDNMATDLLIGRLGKHAIEQALA
                     TAGHHDPASMTPFPTMYELFSVGWGQPDLREQWKQASAQQRAALLEQADSTPYRPDPTR
                     AHTPASNYGAEWYGSAEDICRVHLALQADAVGPAAPVRKILSAVAGIALDRNYWPYIGA
                     KAGGLPGDLTFSWYAEDKTGQPWVVSFQLNWPRDHGPNVTGWMLQVAKQVFALVAPE"
     misc_feature    6898..6900
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7153..7155
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<7616..>8329)
                     /locus_tag="MMAR_RS30690"
                     /old_locus_tag="MMAR_5093"
                     /pseudo=""
     CDS             complement(<7616..8329)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_216567.1"
                     /locus_tag="MMAR_RS30690"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MMAR_5093"
                     /product="polyprenol monophosphomannose synthase"
                     /pseudo=""
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.2e-27,
                     bitscore: 93.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRVLVIIPTYNERENLPLIHRRVKDACPDVHVLVVDDESPDGT
                     GQLADELAAADPGCTYVLHRNVKDGLAAAYLQGFVWGMQRNYSVLVEMDADGSHAPEQL
                     HRLLEAVEAGADLAIGSRYVRGGTVRNWPRRRRVLSKAANTYSRLILGVGVYDITGGYR
                     AYRREVLEALDLDTLESRGYCFQVEMTWRSLNAGFAVVEVPITFTEREVGASKMSGSNI
                     GEGIVQVARWGVKDRL"
     misc_feature    8339..8352
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(8368..9936)
                     /locus_tag="MMAR_RS25550"
                     /old_locus_tag="MMAR_5094"
     CDS             complement(8368..9936)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785692.1"
                     /locus_tag="MMAR_RS25550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5094"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_041324985.1"
                     /transl_table=11
                     /translation="MNRGNVRPKLVLGVIVLGSFIASIDLTIVNVALPTLSRALQASNA
                     ELQWIVDSYAIAAAGLLLAAGNLGDRYGRRGWLTIGLVIVGASSAVAASAGSAQAVIGA
                     RAVMGVGAAIIFPTSLALVTNVFVDSTHRARAIGVWSAVTGIAVVIGPILGGWLIEHFS
                     VGSIFWVNVPIAVVAIVSVNIFVPTSRNPDRPPLDLPGLLVSTVGVTVLTYTLIEAPNI
                     GWASARTAAGFALAVVLLAVFLWLERRTWHPILDLSIFANRRFSGGTAAVTTAYLVMCG
                     FIFVATQYLQFVAAYRAFDTGVRLVPLAFSYAGLSVIAPRIVERVGTTAVVTSGLVMVA
                     VSVACAGGFDAGTPYWLIAAVMAALGSGLGLTMAPASEAIMGSLSPTAAGVGSAVTGVA
                     RQLGACLGVAIVGSVFASVYLRSMSSNAALHGLDPAARAAMRQSMAAAKQVLDQLPVGE
                     APAIRHAVESAFLESFGVGCLACAVFAAVGAVVVAFLLPARGEVRDDVAVSVAASAIGP
                     AEGGK"
     misc_feature    complement(8650..8652)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10933)
                     /locus_tag="MMAR_RS25555"
                     /old_locus_tag="MMAR_5095"
     CDS             complement(10001..10933)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396616.1"
                     /locus_tag="MMAR_RS25555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5095"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_103759359.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.4e-64, bitscore:
                     214.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDNLSPELRLCAGFHIGWWEPDGRDSSVRHGKAVRPALSITCAR
                     AAGGAMDAAIPAAVAVELVHDCSLLHDDIMDGDVTRRHRPAAWVVYGVPMAILTGDALL
                     VLALDLVHEGASGSALRKAALELCAGQSADLAFEQRTKVWLPECLQMAQQKTGALFGVA
                     CQLGALAAGADSLVADQYAQFGRHLGLSFQLVDDILGIWGSESVTGKPVFSDLQSRKKS
                     LPVVAALSSGTAAGAKLETLLGGTEALSDHELSYAADLIEDAGGRAWAEGEALRHRGLA
                     LDALAAAEPEPTAAEDLLALAELMTVRAA"
     misc_feature    complement(10574..10576)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11267..11800)
                     /locus_tag="MMAR_RS25560"
                     /old_locus_tag="MMAR_5096"
     CDS             complement(11267..11800)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396617.1"
                     /locus_tag="MMAR_RS25560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5096"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_012396617.1"
                     /transl_table=11
                     /translation="MTDVTRLILVSHGMTDAMAVGRFPDDEPLNHTGRRWAAPLESNRD
                     SRQYAGPERRCCQSAELLGLRAVTEPRLADLDCGHWRGSRLADIAPADLTAWLSDPGQA
                     PHGGESILELIDRVAGWLASLQGNTVAVTHPAVIRAAILVALDGCPKSFWRIDVAPLSR
                     IALHYRDRRWTLRL"
     misc_feature    complement(11318..11320)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11426..11428)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11808..12575)
                     /locus_tag="MMAR_RS25565"
                     /old_locus_tag="MMAR_5097"
     CDS             complement(11808..12575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011741813.1"
                     /locus_tag="MMAR_RS25565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5097"
                     /product="CbtA family protein"
                     /protein_id="WP_041324987.1"
                     /transl_table=11
                     /translation="MERRLIARGLLAGAVGAVLAFVFARLFAEPIIGRAVEFEDARTEA
                     AHAHGVHEHGAELFSRGVQANAGLGFGVLIFGLAVGALFAVVFCLVYGRVGNPSASPAP
                     RVLSIRLAALAFTVVYLVPFVKYPPNPPAVGQADTIGARTLWYLVMVVASVMLSIVAVY
                     LVRWLSMRMDMFNAGLLAAGAYLVAVTVVMAILPTVAEIPQGFPADVLYEFRLVSLGTQ
                     LVLWASIGLVFSVLVGRGLDERADSGRVQSAAA"
     gene            complement(12590..12799)
                     /locus_tag="MMAR_RS25570"
                     /old_locus_tag="MMAR_5098"
     CDS             complement(12590..12799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020730863.1"
                     /locus_tag="MMAR_RS25570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5098"
                     /product="CbtB-domain containing protein"
                     /protein_id="WP_012396619.1"
                     /transl_table=11
                     /translation="MANSQAAQAGSVDLSAASAALWLAATAVLALLAIYFVGIDQGAVS
                     LVGGDTHVHEFFHDARHLLGFPCH"
     misc_feature    complement(12912..12929)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.56"
                     /tool="antismash"
     gene            complement(12976..13926)
                     /locus_tag="MMAR_RS25575"
                     /old_locus_tag="MMAR_5099"
     CDS             complement(12976..13926)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044496.2"
                     /locus_tag="MMAR_RS25575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5099"
                     /product="PGRS repeat-containing protein"
                     /protein_id="WP_373145641.1"
                     /transl_table=11
                     /translation="MYGSGGSGYNSATSGVGGGAGGAAGLIGNGGAGGAGGAAAAGGSG
                     GQGGWLYGNGGVGGAGGAASTAGGSGGLGGAGGNAGLWGNGGAGGAGGDGTAGAAGVNP
                     TTMPAGNGTPGLTGRDTGGPGGPGADGTEYGQTGGTGGTGGYGRVEGGDGGVGGVGGQG
                     APGGVGGSGGAGGGGGHGGLLVGNGGGGGAGGIGGGGGTGAVGGTGGAGGAGGDSEFAG
                     GNGNTGGDGGTGGTGGAGGDGGNGGAGGAGGLLGHSGNPGLGGEGGTGGGGGDGGHWGD
                     GGGPGSGSRRGMSGSHGSYGQPGGSGADGAHGQPG"
     misc_feature    complement(13162..13164)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<13969..>14043)
                     /locus_tag="MMAR_RS31260"
                     /pseudo=""
     CDS             complement(<13969..14043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_177979.1"
                     /locus_tag="MMAR_RS31260"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="PE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQDVLGLINAPTQALLGRGLIGDGA"
     gene            complement(<14125..14346)
                     /locus_tag="MMAR_RS31265"
                     /pseudo=""
     CDS             complement(<14125..14346)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013127.5"
                     /locus_tag="MMAR_RS31265"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPLVFATPEIIAAAATDLAQIGSAISGANTAAAAPTTEVLAAGAD
                     EVSTVVASLFSRYAQAYQVLGADMAAIHD"
     misc_feature    14455..14469
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.34"
                     /tool="antismash"
     misc_feature    complement(14481..14498)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            complement(14549..17095)
                     /gene="clpC1"
                     /locus_tag="MMAR_RS25580"
                     /old_locus_tag="MMAR_5100"
     CDS             complement(14549..17095)
                     /codon_start=1
                     /gene="clpC1"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010907619.1"
                     /locus_tag="MMAR_RS25580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5100"
                     /product="ATP-dependent protease ATP-binding subunit ClpC"
                     /protein_id="WP_012396621.1"
                     /transl_table=11
                     /translation="MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVA
                     AKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIG
                     TEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESG
                     SPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGK
                     TAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGD
                     IILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALER
                     RFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKA
                     IDLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDREKQLV
                     AQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKR
                     IIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDA
                     LIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIY
                     NSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMK
                     QKVNDELKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSKDMALELTD
                     KAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVVTVDVDNWDGEGA
                     GEDAKFTFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ"
     gene            complement(17473..17814)
                     /gene="lsr2"
                     /locus_tag="MMAR_RS25585"
                     /old_locus_tag="MMAR_5101"
     CDS             complement(17473..17814)
                     /codon_start=1
                     /gene="lsr2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011741818.1"
                     /locus_tag="MMAR_RS25585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5101"
                     /product="histone-like nucleoid-structuring protein Lsr2"
                     /protein_id="WP_011741818.1"
                     /transl_table=11
                     /translation="MAKKVTVTLVDDFDGAGAADETVEFGLDGVTYEIDLSSKNAAKLR
                     GDLKQWVAAGRRVGGRRRGRSGSGRGRGAIDREQSAAIREWARRNGHNVSTRGRIPADV
                     IDAFHAAGS"
     gene            complement(17929..19425)
                     /gene="lysS"
                     /locus_tag="MMAR_RS25590"
                     /old_locus_tag="MMAR_5102"
     CDS             complement(17929..19425)
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lysS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011741819.1"
                     /locus_tag="MMAR_RS25590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5102"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_012396622.1"
                     /transl_table=11
                     /translation="MSSAESDIPEQFRIRRDKRARLLAEGYDPYPVAIERTHTLAEIRA
                     TYADLPTDSATEDIVGVAGRVVFARNTGKLCFATLQDGDGTQLQAMISLDKVGRESLDR
                     WKADVDIGDVVYVHGTVISSRRGELSVLADSWRMAAKALRPLPVAHKEMSEESRVRQRY
                     VDLIVRPQAREVARQRIAVIRAVRNALERRGFLEVETPMLQTLAGGAAARPFVTHSNAL
                     DIDLYLRIAPELFLKRCIVGGFDRVFELNRVFRNEGSDSTHSPEFSMLETYQTYGTYDD
                     SALITRELIQEVADEAIGTRQLPMPDGSVYDIDGEWATIEMYSSLSEALGEQITPETTV
                     ARLRDIASGLDVEIDNSVFGHGKLVEELWEHAVGNKLTAPTFVKDFPVETTPLTRQHRS
                     IPGVTEKWDLYVRGVELATGYSELNDPVVQRDRFADQARAAAAGDDEAMQLDEDFLTAL
                     EYGMPPCTGTGMGIDRLLMCLTGLSIRETVLFPIVRPHSN"
     misc_feature    complement(18157..18159)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18397..18399)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19360..19362)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19547..20365)
                     /locus_tag="MMAR_RS25595"
                     /old_locus_tag="MMAR_5103"
     CDS             complement(19547..20365)
                     /EC_number="2.7.1.33"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_218117.1"
                     /locus_tag="MMAR_RS25595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5103"
                     /product="type III pantothenate kinase"
                     /protein_id="WP_012396623.1"
                     /transl_table=11
                     /translation="MLLAIDVRNTHTVVGLLSGAKQHAKVVQQWRIRTESEVTADELAL
                     TIDGLIGEDSERLTGATGLSTVPSVLHEVRIMLEQYWPSVPHVLIEPGVRTGIPLLVDN
                     PKEVGADRIVNCLAAYQQFAKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAA
                     AARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVARIREDVKGFSADDDV
                     AVVATGHTAPLLLPELHSVEHFDEHLTLHGLRLVFERNREAQRGRLKPAR"
     misc_feature    complement(19607..19609)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20368..20799)
                     /gene="panD"
                     /locus_tag="MMAR_RS25600"
                     /old_locus_tag="MMAR_5104"
     CDS             complement(20368..20799)
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010907615.1"
                     /locus_tag="MMAR_RS25600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_5104"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_012396624.1"
                     /transl_table=11
                     /translation="MLRTMLKSKIHRATVTQADLHYVGSVTIDADLMDAADLLEGEQVT
                     IVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYGTMQDAEARAYQPR
                     IVFVDADNKQIDVGHDPAFVPAFDIPGAEELLNPRIGAR"
     misc_feature    complement(20792..20806)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(20794..20796)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ccggccggct gtcagaccca gccgatatgg tcaccgcgtg gccaacgcac gtttgcaata
       61 ccgctgcgcg gactgccggt atctcaccgc caagtgggtg gggcgatgcc cggagtgcag
      121 cagctggggc accgtcgaag aagtgtccgt tctcagcgca gtcggcggag gcagtcgcct
      181 gggtcgccgg gcgcacggtc cggcggtacc gacgtcgcag gccgttccga taagttccgt
      241 ccagcccaat ctcagccggc accgccctac cggcatcgac gaactcgacc gggtgctcgg
      301 cggcggtgtg gtgccgggtt cggtgacgct gctggccggc gagcccggtg tcggcaagtc
      361 gacgctgctg ctcgaagtgg cccaccgctg ggcgcagtcg gggcaacgcg ttttgtacat
      421 ctccggcgaa gagtccgcgg ggcagatccg gctgcgcgcc gaccggatcg gctgcggcgg
      481 cccggcggct cccgatatct ccgaggtctc agcgatcgac aacagcgcgg agatctatct
      541 ggccgccgaa tccgacctgc acgcggtctt ggaccacatc gacacggttg ggtcggcatt
      601 ggtgatcgtc gactcggtac agacgatgtc caccagcgag gtcgacggcg ttaccggcgg
      661 ggtgacacag gtgcgcgccg tcaccgccgc gctcaccgcg gcggccaagt ccaatggctt
      721 cgcgctgatt ctcgtcgggc acgtcaccaa ggatggagcc atcgccggcc cccgctcgct
      781 agaacacctg gtcgacgtcg tgctgcactt cgaaggcgac cgcaacggcg ggttgcgaat
      841 ggtccgtggc gtcaagaatc ggttcggcgc ggctgacgag gtgggttgct tcctgctgca
      901 cgataacggg atcgagggcg tagccgatcc gtccaacctg ttcctggatc aacgccccac
      961 accggttccc ggcaccgcga tcacggtgac cctggatgga aaacgccccc ttatcgggga
     1021 agtccaggcg ttgctggcga cgccgaacgg cggggcaccc agacgcgctg tcagcgggat
     1081 cgaccatgcc cgggccgcca tgatcagcgc cgtcctggaa aaacacgcgc ggctgtcact
     1141 ggccgtcaac gacatgtatc tgtccaccgt cggcgggatg cggttgaccg atccctcatc
     1201 ggatctggcc gtcgcgatcg cactggcctc ggcgtatgcg aacctgccgc tacccaccac
     1261 cgcggtgatg atcggcgagg tcggcctggc gggcgacctg cggcgggtca acgggatgga
     1321 ccggcgcctg gccgaggccg cccggcaggg attcaacatc gcactggtcc cgcccggctg
     1381 cgaggcggtg ccggcgggcc tgcgcacgct ctgcgcgccc acaatcgtgg ccgcactcga
     1441 gcacatgatc gacatcgccg accaccgcag cgtcccttcg gcgaaggtgc atcggctaga
     1501 cacctcccac tagcggcgga cgcatagcag aatgcacgct gtgaatcgtc cgacacttcg
     1561 tgaggctgtt gcccggctgg cgcccggcac ggggctacgg gacggcctag agcgcattct
     1621 gcgcggccgc accggagccc tgatcgtgct gggccacgat gagaacgtcg aggccatctg
     1681 cgacggcggg ttccccctcg atgtgcgcta tgcgcccacc cggttacggg aactgtgcaa
     1741 aatggacggc gccgtggtgc tgtccaccga tggcagccgg ttcatccggg ccaacgtgca
     1801 gctagttccg gacccgtcga tacccaccga cgaatcgggc acccgccacc gttcggcgga
     1861 acgggccgcc atccagaccg gctatccggt gatttcggtg agccactcga tgaacatcgt
     1921 gaccgtctac gtcggcggtg agcgacacgt gctgagcgat tcggccacca tcctgtcgca
     1981 cgccaatcag gccatcgcga ccttggagcg gtacaagacc aggctcgacg aggtcagccg
     2041 gcagctatcc cgcgcggaga tcgaggactt cgtgacgcta cgcgacgtga tgacggtggt
     2101 gcagcgactt gagttggtgc ggcgaatcgg catcgagatc gacaacgacg tggtcgaact
     2161 cggcaccgat gggcgacaac tgcggctgca gctcgaggag ttgctcggcg acaacgaaac
     2221 cgcccgggag ttgattgtcc gggattacta cgccaaccac gaaccgctgg ccaccgcaca
     2281 gatcaccgcg accctcgacg agctggatgc catcaccgac accgagctac tcgatttcaa
     2341 cgcgctggcg aagatcttcg gatatccgtc caccaccgag gcgcaggact cggcgctgag
     2401 cccgcgcggc taccgcgcca tgtcgggcat cccgcggctg cagttcagcc ataccgacct
     2461 gctggtccgg gcctttggca gcctgcaggg cttgctcgcg gccagcgcca gcgacctgca
     2521 atcggtggaa ggcatcggcg cgacgtgggc ccctcacgtc cgagaggggc tatcgcagct
     2581 ggccgagtcg acgatcgccg accagtgacg tgcgcccgcc tacccgccct gggcgggcgg
     2641 cgcctcgggc ggtggcgcca aagccgggcc gggagccggt aacggaccgg gaggctgcgg
     2701 cgcaggattc aagatgaatg gaaccggctg cgaccgcagg ttacccagct gcacgaccag
     2761 gttgtaggtt ccgggcccaa tcgcgggcct cggcaatggg cacttgggcg ccgatcccat
     2821 cccggtccac gtcaccgcgg tagtcacctg ctcaccgggg gcaaatgtct tgaccaaggt
     2881 ctcattggat ggcgcgcagt ccaggttgga ccacaaccgc ttgttgtcca gcgagtacac
     2941 gtaggccgcg agcaccgcgg cgcccacgtc ccgcttgcag gccaccagcc cgatattggt
     3001 gacgaccatg gtgaacttcg gctggtcacc gatgtagtac tggggcgcgt tcgtcagacc
     3061 cttgacggcc aacgtggaat ccgggcagtc gtcgccctcc ttgagcaccg gcggcggttg
     3121 taccgcggcg gtgggggtgg gtgtctccgg attctgcccc tgcggcggcg cgcccggagc
     3181 attaccttcg gtctgcccgg ccggttgcgg cgcttgcggc gcacttgacc ccggatggtc
     3241 ttgcgcaccc gccggtttat cggcattggc aggcttggcg cccgcattac tcccgacgaa
     3301 ggcgatcaca gcggcgacgg ccaccccgat cactacgacc gcgatgccca gggccagtcc
     3361 cctgcgccgc cagtagatct cggtgggtag cgggccacgc ggttccagat ccagcacatt
     3421 cacaccgtag gcccaggtca cgccgactcg ttcgacccga cccggcgtgt cgccgggtta
     3481 gctggggaac ggccgtgtta ggggctctcc aagacgtgcc ctaaccgccc ctatgcgccg
     3541 atatcaccga catggtcgcg cagcaccgcc tgtccgtcgg aaagctggta ggtgaccccc
     3601 acgatggcca gcgtgcccgc cgcgactcga ttcgatatcg ccgtcgaccg cgccatcagc
     3661 tgggcaaccg tctcctgaat gtggcgctgt tcgaactcgt cgacccgctt caggccgtcc
     3721 cgccgaccca tcagaatcga cggagccacc cgctccacca cgtcccgcac gtaaccaccg
     3781 ggcacgctgc cctcgttgat cgccgtcaaa gccgcgttga cggccccgca gctgtcatgg
     3841 ccgagcacga ccacaagcgg cacgttgagc accgtaaccg cgtactcgat ggagcccaac
     3901 acggccgagt cgatgacgtg accggcggtg cggaccacga acatgtcgcc caggccctgg
     3961 tcgaagatga tctcggcggc cacgcggctg tccgcgcacc cgaagatgac cgccgtcggc
     4021 ttctgcccgg aagccaggct ggcacggtga tcgacgcttt gactggggtg caggggcttg
     4081 ccggcgacga atcgctcgtt accctcactg agtgctttcc aggcggttat cggattggtg
     4141 ttgggcatgc cagccattgt gccgcaacct tcgatgacct gccccgaaca cataccggcc
     4201 actaatcttg tcgcctggta tgagcgttgt tgccgcgacc tgccctggcg ggcgcccgac
     4261 gtgagcccgt ggcagatcct ggtcagcgag ttcatgctgc agcaaacccc ggtatcgcgg
     4321 gtgctgtcga tctggccgga ctgggtgcgg cgctggccca ccgcatcggc gacggcgacg
     4381 gcgacggccg ccgatgtgct gcgcgcctgg ggcaagttgg gttatccacg gcgggccaag
     4441 cgcttgcatg aatgcgccat ggtcgtcgcc ggtgaccacg acgacgtggt tcccgacgac
     4501 gtcgataccc tgctgaccct gcccggcgtc gggagctaca ccgcacgcgc ggtggcctgc
     4561 ttcgcgtacc ggcagcgggt tccggtggtg gacaccaatg tccggcgggt ggtggcccga
     4621 gccgtccatg gccgcgccga agcgggttca ccgtcggcca cccgcgacca tgccgaggtg
     4681 tccgcactgc tgcccgacga cgagctggcg ccgcggtttt cggtggccct gatggagctg
     4741 ggtgcgacgg tgtgtaccgc ccgggcgccg cgatgcggac agtgcccgct tgccgagtgc
     4801 gcctggcggc gggccggcta tccgcccgca accggcccgg cccggcgcgt tcagacctac
     4861 gccggaaccg atcgtcaagt gcgcggacgg ctgctagatg tgttgcgcga caacaatggg
     4921 ccggtcactc gtgcgcagct ggacgtggcg tggctgaccg ataccgcgca gcgggaccgg
     4981 gcgctgtact cgctgctggc cgatggcctg gtcacccaaa ctgccgatgg gctcttcgcc
     5041 ctggccggcg aagcgtagga gctcgttacc gaacgcgctc ggcggccagg aacgcctcga
     5101 cagcctgccg atacgccagc tgcgcctcgt cgtggaccag atgtccggcc tcgggaacat
     5161 gcagatattt agttgaccgg tcgacttcgg ccatcgcaag catctggccc ggcggcgtca
     5221 cggagtttcc ggcctcgatc agaagcgccg gctgccgcac cgcccgccat tgtgcccagt
     5281 agtcgcgcgt accccattca gcggcgatct ggatccaccg cgaggtgtgc ccatgcaggc
     5341 gccaccccgt ggccgtgcgg tcgaaggctt ccagaaagta ctgcccggca agcggcccga
     5401 attccgcgaa tacctgatcg gccgaatcga attcaacggg aagtgcgtgc aaccacggct
     5461 cccacgggcc ggtggtgcgg ccgacgaaat ccggcgccat gtcctcgacc accaacgccg
     5521 acaccagccc gggacgctcg gcggccaaac accacgaatg cagggcaccc atcgaatgtc
     5581 cgaccagcct ggccggcccg cccagctcgg ccaccgcctc acccaggtcg gccacgaaac
     5641 gttcggtgct gatcggatac ggatcgtcga cgtcgcggcc gcggtgccag ggcgcgtcgt
     5701 aggtatacac ggcaccgagg cgagtcagcc acggcagctg acgcgaccaa gtgctgcccc
     5761 ggcccatcag cccgtgcacc aggaccaacg gctctccctc tccgccgtga taggtcaaca
     5821 gatcggtggg catagaccta tcttgcgcgg cgtgccgagg cttgagccag gcgcggtaac
     5881 ctagccgaat gccagtggtg aagatcaatg caatctcggt gccggccggc gctggccccg
     5941 aactggaaaa gcgcttcgcc caccgcgcgc acgcggtgga taactctccg ggctttctcg
     6001 gctttcaatt gctgcgtcca gtcaagggtg aagaccgcta cttcgtggtg acacactggg
     6061 agtctgatga agcgttccag gcttgggcga acgggcccgc caaagaagct catgccggcg
     6121 aacgggccaa tcccgtgtca accggcgcct cgctattgga attcgaggtt gtgctcgacg
     6181 ttgcagggaa cacgccggct gactagccgg cgccgcaacc ggctgcgccg cgcgacggtg
     6241 ctcaccgccg ccgcggcgat ggtgctgacg ctgacacctg ggtgctcgtc ctcgccaacc
     6301 ccatcggcca acgcggccaa cccgcagcgc cggatcgaca ccgtgactcc accgggtctg
     6361 cgcgcccagc agaccatgga catgctcaat tcggactggc cgatcggccc ggccggagtg
     6421 gccacgctgg ccgcgcccag caaggtcgac tcggtcgaag ccaccatgga gggactctgg
     6481 tgggaccggc cgttcgccct cgacagtgtg gacatcagcg ccagcgtggc aacgctgcac
     6541 ctgacctcct cttacggcgc gcgacaggac atccgcctgc acaccgatga cggcggctgg
     6601 gtggaccggt tcgaactcga gacgcttccc ccaccgacga tcaccgcctg gcgcgacgtc
     6661 gatgccgtat tgagcaagac cggcgcccga tactcctacc aggtgtccaa ggtcgaaaag
     6721 ggacagtgca ctcgagtcgc gggcaccaac accaaccaac ctctacccct ggcatcgatt
     6781 ttcaagttgt acgtgctgca tgccctggcg gatgcgatca agagcggcac cgcatcctgg
     6841 gacgaccagc tgaccgttac cgccaagagc aaggccgtcg gctcctctgg cctggaatta
     6901 tctcccggcg accacgtttc ggtacgccgg gcggccgaga aaatgatcgc caatagcgac
     6961 aacatggcca ccgacttgct gatcgggcgg ctgggcaagc acgccatcga gcaggcgctg
     7021 gccaccgccg gccatcacga tccggccagc atgactcctt tccccaccat gtatgagctg
     7081 ttctcggtgg gttggggtca acccgatctg cgggagcaat ggaagcaggc gtctgcgcaa
     7141 cagcgagcgg cattactcga acaggccgat tcgactccgt accgccccga tccgactcgt
     7201 gcccacaccc cggcctcaaa ctacggtgcc gaatggtatg gcagcgccga ggacatctgc
     7261 cgggtccacc tggcactgca ggccgatgcg gtcggtcccg ccgcaccggt gcgaaagatc
     7321 ctgtccgccg tcgcgggcat tgcgctagac cgcaactact ggccctacat cggcgcgaaa
     7381 gccggtggtc tgccgggaga cttgaccttc agctggtatg cggaggacaa gaccgggcaa
     7441 ccgtgggtgg tgagcttcca gctgaactgg ccgcgtgacc atggaccgaa tgtgaccgga
     7501 tggatgctgc aggtcgccaa gcaggtcttc gcgctggtcg ctcccgaata gcggtccata
     7561 ccgcggctgc gaaccgttgg gcggcaagcg aaattcgggc ggttcgcaga ccccgcagtc
     7621 ggtctttgac gccccatcgg gcgacctgga ctattccctc gccgatgttg gatccgctca
     7681 tctttgaggc accgacctcc cgctcggtga aggtaatcgg cacctccacc acggcgaagc
     7741 cggcattgag gctgcgccaa gtcatttcaa cttggaagca atagcccctg gattcgagag
     7801 tgtcgaggtc gagtgcctcg agcacctcgc ggcgataggc ccgatagcca ccggtgatgt
     7861 catagacacc gacgcccagt atcaaccgcg agtacgtatt ggccgccttg gacaacacgc
     7921 gccgtcgccg tggccagttg cgtaccgtcc cgccgcgcac atatcgggac ccgatggcca
     7981 gatcggcgcc cgcctcaaca gcctccaaca gtcggtgcag ctgttcggga gcgtggctac
     8041 catcggcgtc catctcgact agcaccgagt aattgcgctg cataccccag acgaaaccct
     8101 gcaggtaggc cgcggccaga ccgtccttga cgttgcggtg caacacgtat gtgcagccgg
     8161 ggtcggcggc ggccagctcg tcagcgagtt ggccagtgcc atccggactt tcgtcatcaa
     8221 cgacaagaac atgcacgtct gggcaggcat ccttgacgcg ccggtggatc aggggcaggt
     8281 tctcccgctc gttgtacgtc gggattatca ccaggacccg ccggctccga ccagtgcccg
     8341 aatgctcatg cgggtctcgc tcgtgggtca tttgcctcct tcagctggcc cgatggccga
     8401 ggccgccacc gacaccgcaa cgtcgtcgcg gacctcaccg cgcgcgggca acaggaatgc
     8461 gaccacgacc gcgccgaccg cggcgaaaac cgcgcacgcc agacaaccga cgccaaagct
     8521 ttccaggaat gccgattcga cggcatgccg gatggctggc gcctccccga cggggagttg
     8581 gtcgagcacc tgcttggctg ccgccatcga ctgccgcatc gcggcacgcg ccgccggatc
     8641 gaggccatgt aacgccgcat tactgctcat cgacctcagg tagaccgatg cgaagacgct
     8701 gcccacgatg gccactccca ggcatgcccc gagttggcga gccaccccgg tcaccgccga
     8761 cccgacaccg gcggcggtcg ggctcaatga acccatgatc gcctcactgg ccggggccat
     8821 ggtgaggccc agtccgctgc cgagcgcggc catcaccgcc gcgatcagcc aatacggcgt
     8881 gccggcgtcg aagccacccg cgcaggccac ggaaaccgcc accatcacaa ggccactggt
     8941 gaccactgcg gtggtaccca cccgttcgac aatgcgcgga gcgatgacac tgaggcccgc
     9001 ataggagaac gcaagcggca ccagccgcac tcccgtatcg aacgcgcggt aggcagccac
     9061 aaattggagg tactgcgtgg caacgaagat gaagccgcac atcaccagat aggcggttgt
     9121 gacagccgcg gtccctccgg agaaccggcg gttcgcgaag atcgacagat caagaattgg
     9181 gtgccacgtt cttcgctcca accagaggaa caccgcgagc aagacgaccg cgagcgcaaa
     9241 gcccgcagcg gttctcgcac tggcccagcc gatgttgggc gcctcgatga gcgtgtaggt
     9301 caagacggtg acgccgacgg tcgatacgag cagacccggc aggtcaagtg gtgggcgatc
     9361 ggggttgcgc gaagttggta caaatatgtt tacgctgact atggcgacga ccgcgatcgg
     9421 tacatttacc caaaagatcg agcccaccga gaagtgctct atcagccatc cgcccagaat
     9481 cggcccaata accaccgcga tgccagtgac cgccgaccag actccaattg ctctggcgcg
     9541 gtgcgtcgaa tcaacgaata catttgtgac cagcgccagc gatgtcggaa agatgatcgc
     9601 ggcaccgacc cccatcaccg cgcgtgcccc gatgaccgct tgcgccgagc cggcactggc
     9661 ggccaccgca gacgaggcgc cgacaatgac aaggccgatt gtgagccagc cgcgcctgcc
     9721 atagcgatcg cctagattgc ctgccgccaa gagcaatccg gccgcagcaa tcgcatatga
     9781 atcgacgatc cactgcagtt cggcgttgct ggcctgcaac gcacgagaca acgtgggcag
     9841 cgcgacattg acgatggtca aatcgataga tgcgatgaag ctgcccaaaa cgatgacacc
     9901 cagcaccaac ttcggacgaa cgttgccgcg gttcatggat acccgaatcc cggacacttc
     9961 gtcggggaca gccccgcgaa acggccgcac gctcggggca tcacgccgcc cgcacggtca
    10021 tcagctcagc cagggccagc aaatcctccg ccgcggtcgg ctctggttcg gcggcagcca
    10081 gagcgtcaag agccaggccg cgatgccgca gcgcctcgcc ctccgcccaa gcccggccac
    10141 ccgcatcctc aatcaagtca gcggcgtagg acagctcatg atcgctgagg gcctcagtgc
    10201 cgccaagcag ggtttccagc ttggcgcccg ccgccgtacc agaggacagc gcggctacca
    10261 ccggcaacga cttttttctc gactgcagat cggagaacac gggtttgccg gtaaccgatt
    10321 cactgcccca gattccgaga atgtcgtcga ccagctgaaa agagagtccc aagtggcgac
    10381 cgaactgcgc gtactggtcg gcaacaagac tgtcggcgcc ggccgcaagc gcacccaatt
    10441 gacacgccac gccgaacaga gcgcccgtct tctgttgtgc catttgaaga cattcgggca
    10501 accagacttt ggtgcgttgc tcgaaggcga ggtcggcgga ttggccggcg cacaactcca
    10561 gtgccgcttt gcgtaacgcc gagcccgagg ccccctcgtg aaccaagtcc aacgccagca
    10621 ccagcagcgc gtcaccggtg agtatcgcca tcggtacgcc gtagaccacc cacgccgccg
    10681 ggcgatgccg ccgagttacg tcaccatcca tgatgtcgtc gtgcagcaac gaacaatcgt
    10741 gcaccaactc gaccgctacc gcagctggaa tcgcggcatc cattgccccg ccagctgcgc
    10801 gcgcgcaggt aatcgacagg gccggccgaa cagccttgcc atggcgcacc gaactatcgc
    10861 gcccatcggg ttcccaccag ccgatatgaa accctgcgca aagccgcagc tcaggcgaga
    10921 gattatcgat cacagctcgc tgcttcggtt caataagcag tcgaatatcg ttcagcaata
    10981 acgtaatccg cgcgggagtt gtcgaagccc gaaccggacg cgccatttgc gacatcgcca
    11041 ccgccctcct ggattgatct cagaaggggc ccaatcggcc cattaacaag cctaaaattt
    11101 acaacagtgt cgataagcta ccacggtcca ttcacccgcg ctttccaacc aaccttggat
    11161 ggtcgcgacg cacgaaatcc ggccgcgcaa ccgcagccac agctccgaac cgattgttgg
    11221 agtggccaat tgcgcagggc gggtaaatcg gggactttcc aacccgctaa aggcgcagtg
    11281 tccagcgccg atcgcggtaa tgcagcgcta tccgacttaa cggtgcaaca tcgatgcgcc
    11341 agaacgactt cgggcagccg tcgagggcaa ctagaattgc tgccctgatt acggcgggat
    11401 gggtcaccgc gaccgtattt ccttgtaacg acgccaacca tccggcgacc cgatcaatca
    11461 actcgagaat cgactcaccg ccgtgcggcg cttgcccggg atcactcagc cacgccgtaa
    11521 ggtcagcggg cgcaatgtcg gccagcctcg aaccgcgcca atgcccacaa tccagatcgg
    11581 ccagccgcgg ctcggtgacc gctcgcagtc ccagcagctc cgcgctttga cagcaacgcc
    11641 gctcgggccc ggcgtattgc cgcgagtcgc ggttgctctc caatggcgcc gcccatcggc
    11701 gaccagtgtg gttgagcggc tcgtcgtcgg gaaagcggcc gacggccatc gcgtcggtca
    11761 tcccatgcga caccaggatc aaccgcgtga catcggtcat cgaacagtca cgccgcggcg
    11821 ctttgcaccc gtccgctatc ggcccgctcg tccagccctc gccctaccag caccgagaag
    11881 accagtccga tggatgccca caacaccagt tgggttccca acgagaccaa cctgaactcg
    11941 tagaggacat cggcgggaaa gccctggggt atctcggcaa cagtcggcag gatcgccatg
    12001 accaccgtga ccgcaaccag gtacgcaccg gccgcaagca acccggcatt gaacatgtcc
    12061 atccgcatcg agagccaccg caccagatag acggccacga ttgacaacat caccgacgcc
    12121 accaccatga ccaggtacca cagggtgcgt gcaccgatgg tgtccgcttg accgaccgcc
    12181 ggcgggttgg gcggatactt cacgaacggg accagataca ccacggtgaa ggccagcgcc
    12241 gctagccgaa tggaaagcac ccgcggtgcg gggcttgccg acgggtttcc cacgcgtccg
    12301 tacaccagac aaaacacaac ggcgaaaagg gctcccaccg cgaggccgaa aatcaggact
    12361 ccgaaaccca atccagcgtt ggcctgcacg ccgcggctga acaattccgc accgtgctcg
    12421 tgcaccccgt gagcgtgcgc agcttcggtg cgggcgtctt cgaattcgac agcccggccg
    12481 atgatgggtt cggcgaacag ccgggcgaac acgaacgcca acacggcacc caccgcgccc
    12541 gccagcagac ctcgtgcgat cagccgccgc tccacgttag ccgcccggct cagtggcacg
    12601 ggaagccgag caaatgcctg gcgtcgtgga agaactcatg aacgtgggta tcgccgccca
    12661 ccagcgatac cgccccttga tcgatgccga cgaaatagat cgccaacagc gccaggacag
    12721 ccgtggcggc cagccacagc gctgcgcttg ccgccgatag gtcaaccgaa ccggcctggg
    12781 cggcctgaga gttcgccacg gtcaactcct tctggggatc tcgcgcccca cttgggtagc
    12841 cgatgacggg cgccgggtct gactagacag tggcgcgacc gttctggaat ttcaccagat
    12901 tccgtcgccc atcaacaaca atgaaacaac accggccagt gtaaaccggt agttcccagg
    12961 ggtcgatcga caaaatcagc ccggctggcc gtgcgccccg tccgcgcctg aacccccggg
    13021 ttgtccgtaa ctgccatggg atccagacat gcccctgcgc gatccacttc cggggccccc
    13081 accgtcgccc caatgaccgc cgtcgccacc accgccaccg gtaccgccct cgccgccaag
    13141 cccggggtta cccgagtgcc ctaacagtcc tcccgcgccg cccgcaccac cgttgccgcc
    13201 atcgccgccg gctccgccgg tcccgccagt gccgccgtcg ccaccggtat tgccattgcc
    13261 gccggcaaat tccgagtctc cgccggcacc gccggcgccg ccggtaccgc cgaccgcacc
    13321 ggtgccaccg ccgccgccga tgcccccggc accgccgccg ccaccgttgc cgacgagtag
    13381 cccgccatgg cctccaccac ccccggcgcc gccgctaccc ccgacgccac ctggagcgcc
    13441 ctgcccaccg accccgccta cgccgccgtc gcccccctcc acacggccgt agccgccggt
    13501 accgccggtg ccgccggtct gcccgtactc ggtgccgtcg gcgccgggac cgccaggacc
    13561 gccggtgtca cgtccggtaa gacctggggt tccgttgccg gccggcatgg tcgtggggtt
    13621 gacaccggcc gcgccggccg tgccgtcccc gcccgcaccg ccggcaccgc cgttgcccca
    13681 gagcccggcg ttgccgccgg cgccgcccag accgccgcta ccgccggccg tgctggcggc
    13741 cccgccggcc ccgccaacgc cgccgttgcc gtacagccag ccgccttgac cgccggaccc
    13801 gccggccgcc gcggctccgc ccgcccctcc ggcaccgcca ttgccgatca ggcccgcggc
    13861 cccgccggca ccgccgccca ctccggaggt ggcgctgttg tagccgctac cgccgctgcc
    13921 gtacaagaac cccccgtcat acccatcggg gtgcgatgcg gttcccgcgg caccgtcgcc
    13981 gatcagccct cgccccagca gggcctgcgt gggtgcgttg atcaacccca acacgtcctg
    14041 ctgcacggtt tgtagcgtcg aactgttggc cgactccaca ccggcatacc aatttgcgcc
    14101 ggcgttcaag gcctgcacga actggtcatg aatggccgcc atgtcggcgc ccagcacctg
    14161 ataagcctgg gcgtagcggg agaacaggga cgcaacgacc gtcgagacct catcggcacc
    14221 ggcggcaagc acttcggtgg tcggagccgc cgccgcggtg ttggccccgc tgatcgccga
    14281 cccaatctgc gccaagtccg ttgctgcggc cgcgatgatc tccggtgtgg caaaaactag
    14341 cggcatggct cgcctcctcg gcacatgacg caacccagca tcggcctgat cactgccgga
    14401 tagatcaata gaaacgtatc gccatgtccc gccgcgacat gcggagcttc aacgaacttt
    14461 caggaaatcg gaagcagctc gcaacgtccg cttaacatgt gacgggcctg ccagaggcaa
    14521 gcccgtcaca tgttttcaga gtgttcggtt actgctcggt gggcccaggt cccccggcgc
    14581 tgtgtgctcc ggcctttgcc aggtccggct cactcggcgg cttgcgggta ccggtgaacg
    14641 taaatttcgc gtcctcaccg gcgccctcgc cgtcccagtt gtcgacgtcg acggtgacga
    14701 cctgtcccgg accgacctcc tcgaagagga tcttctccga gagctggtcc tcgatctcac
    14761 gctgaatggt tcgccgcagc ggacgagcac ccaagaccgg gtcgaaaccg cgcttggcca
    14821 gcagcgactt tgccttgtcg gtcagctcga gcgccatgtc cttgctcttg agctggttgg
    14881 cgacgcggcc gatcatcagg tcgaccatcc ggatgatctc gtcgcgagtc agctggtgga
    14941 agacgatgat gtcgtcgatg cggttgagga actccggccg gaagtgcttc ttgagctcgt
    15001 cgttgacctt ctgcttcatc cgctcgtagt cgttctcgcc gccagtctgg ctgaacccga
    15061 ggccgacggg cttggaaata tcggatgtcc ccagattcga cgtgaagatc agcacggtgt
    15121 tcttgaagtc gaccgtgcgg ccctggccgt cggtgagccg gccgtcctcg aggacctgca
    15181 acagactgtt gtagatctcc tggtgtgcct tctcgatctc atcgaagagc accacgctga
    15241 acggcttgcg ccgcaccttc tcggtgagct ggccgccctc ttcgtagccg acatatccgg
    15301 gcggagcacc gaagagccgg gacgcggtga accggtcgtg gaactcgccc atgtcgatct
    15361 ggatgagcgc gtcgtcgtca ccgaacaaga agttggccag cgccttggac agctcggtct
    15421 taccgacacc ggaagggccg gcgaagatga acgatcccga cgggcgcttc gggtccttca
    15481 gcccggcgcg ggtgcggcgg atcgccttgg agaccgcctt gaccgcgtct tcctggccga
    15541 tgatccgctt gtgcagctca tcttccatcc gcagcaggcg ggtggtttcc gcctcggtga
    15601 gcttgaacac cgggatgcca gtccagttgc ccagcacttc ggcgatctgt tcgtcatcga
    15661 cttcggcgac cacgtcgaga tcgcccgaac gccattgctt ttcacgctcg gcacgctgcg
    15721 ccaccagttg cttctcccgg tcgcgcaggc tcgccgcctt ctcgaagtcc tgggcgtcga
    15781 tcgccgattc cttctcccgg cgcgcgtcgg cgatcttctc gtcgaactcg cgcaggtctg
    15841 gcggcgcggt catgcgacgg atccgcatcc gggcgcccgc ctcgtcgatc aggtcgatcg
    15901 ccttgtccgg caggaaccgg tcgttgatgt agcggtcggc cagcgtcgcg gcggccacca
    15961 tcgcggaatc ggtgatcgac acgcggtggt gcgcctcgta gcggtcccgc aggcccttga
    16021 ggatctcgat ggtgtgctcg accgtcggct cccccacctg caccggctgg aaacggcgct
    16081 ccagcgcggc gtccttctcg atgtacttgc ggtactcgtc gagggtggtg gcaccgatcg
    16141 tctgcagctc gccgcgagcc agcttgggct tgaggatgct tgcggcatcg atcgcgccct
    16201 cggcggcacc cgccccgacc agcgtgtgca gctcgtcgat gaacaggatg atgtcgccgc
    16261 gggtattgat ctccttgagc accttcttca ggcgttcctc gaagtcaccg cggtagcgcg
    16321 aacccgcgac cagcgagccg aggtccagcg tgtagagctg cttgtccttc agcgtctcgg
    16381 gcacctcgcc gtgcacgatg gcctgcgcca ggccctcgac cacagcggtc ttgcccacgc
    16441 cgggctcacc gatgagcacc gggttgttct tggtgcgccg ggagagcacc tgcatgaccc
    16501 gctcgatttc cttctcgcgg ccgatgaccg ggtccagctt gccttccatg gcagccgcgg
    16561 tcaggttgcg gccgaactgg tcgagaacca gcgacgtgga gggagagccg gactcccctc
    16621 cccggccgcc ggtgcctgcc tcggcggcct ccttgccctg gtagccgctc agcagctgga
    16681 tcacctgctg gcgcacccgg gtcagttcgg cgcccagctt gaccagcacc tgggcggcca
    16741 caccctcgcc ctcgcgaatc aggccgagca ggatgtgctc ggtaccgatg tagttgtggc
    16801 cgagctgcag cgcctcgcgc aggctgagtt cgagcacctt cttggcgcgc ggagtgaacg
    16861 ggatgtgccc ggacggtgcc tgctggccct ggccgatgat ctcttcgacc tggctgcgca
    16921 caccttccag cgagatcccg agcgactcca gcgacttggc cgcaacgcct tcgccttcat
    16981 ggattagccc cagcagaatg tgctcggtgc cgatgtagtt gtggttcagc atccgggcct
    17041 cttcttgcgc caggacaacg acccggcggg cacggtcggt aaaacgttcg aacatcggcg
    17101 gttacctgct ctccctcatc ggtactttgg tcggtcctga accagtccag ctcggccccg
    17161 cgtacctgca gtccactgta atggtcggcc tgccaggctt cataacaacc ttgcagtgcc
    17221 gtgcggttcc cggctgcaac tccggtgtgg ggcccgaatc acccgaatca gatacacccg
    17281 tgacccagac ccggcgcccg agaagccgcg ccggcctcgt tttcttcctg ctacaacaga
    17341 accgcaacac gttaacgagg aaaaccgccg aagtgtttcc cgtgtcggcc gaagatcggt
    17401 ttcgccacga gcgaaaatga catagcaccg tcgcccaggc ttagcctggg cgacggtaat
    17461 agatcgagat cgctatgaac cggcagcgtg gaatgcgtcg atgacgtcgg ccgggatacg
    17521 gccacgggtc gacacattgt gcccattacg gcgtgcccat tcccggatgg ccgcgctttg
    17581 ctcgcggtcg atagcgccgc ggccacgtcc ggatcccgaa cgcccacgtc gccggccacc
    17641 gacgcgccga cccgccgcaa cccattgctt cagatcaccg cgcagtttcg cggcattctt
    17701 ggaagaaagg tcaatctcgt aggtcacccc gtcaagcccg aattcaaccg tttcgtcagc
    17761 agcaccggca ccgtcgaaat cgtcgaccaa ggtgacggta actttcttag ccattggctt
    17821 accctcgcgt ttcttcctat gcgtcgcaat acaggatgga tagtctcccc gcgcaccaat
    17881 gtgccataag taagcaaaat tctcaatcca gacacaacca ccggcagttc agttggagtg
    17941 agggcgaaca atcgggaaca aaactgtctc cctaattgac agtccggtca aacacatcaa
    18001 caaccgatcg atgcccattc cagttccagt acacgggggc atcccgtact ccagagccgt
    18061 cagaaaatct tcgtcaagtt gcatcgcctc gtcgtcaccc gcggccgccg cacgggcctg
    18121 atcagcgaat ctgtcccgct ggacgacggg atcgtttaat tccgagtacc cggtagccag
    18181 ttcgactccg cgcacgtaga gatcccactt ctcggttact ccggggatac tgcggtgctg
    18241 acgagtcaat ggcgttgtct cgactgggaa atccttgaca aatgtgggcg ccgtcaactt
    18301 gttgccgaca gcatgttccc agagttcctc gacaagtttg ccgtgaccaa aaacactgtt
    18361 gtcaatctct acgtcaagtc cgcttgcgat gtcacgtaag cgagcaaccg tcgtctctgg
    18421 cgtgatctgt tcccccagtg cctccgacaa ggaggaatac atctcgatag tcgcccattc
    18481 tccgtcgatg tcgtacacgc tgccgtcagg catcgggagt tgtctggttc cgatcgcctc
    18541 gtcagcaact tcttgaataa gctctctggt gatcagggcc gaatcgtcat aggttccata
    18601 ggtctgatac gtctccagca tggagaattc cggggaatgg gtggaatcag acccttcgtt
    18661 tcggaacacc cgatttagtt caaagaccct gtcgaaaccg cccacgatgc aacgcttgag
    18721 gaacagttcc ggcgcgatac gcaggtaaag atcgatgtca agggcattgg aatgggtgac
    18781 gaacggccgc gccgcagcgc cgccggccaa ggtctgcaac attggcgttt cgacttcgag
    18841 aaacccgcgc cgctccagcg cattacgcac cgcacggatt accgcaatcc gctgtcgcgc
    18901 gacctcccgc gcctgcggac gcacgatcaa atcgacgtag cgctgacgaa cccgcgactc
    18961 ctcgctcatc tccttgtgtg cgaccggcag cggccgcaag gccttggcag ccatccgcca
    19021 ggaatcggcg agcaccgata gttcgccccg acgggagctg atcacggtgc cgtgcacgta
    19081 gacgacgtca ccgatgtcga cgtcggcctt ccacctgtcc agcgattcgc ggcccacctt
    19141 gtcgaggctg atcatcgcct gcagctgggt gccgtcgccg tcctgcagtg tcgcaaaaca
    19201 cagtttcccg gtgttacgcg cgaacaccac tcgacccgcg acaccgacga tgtcctcggt
    19261 cgccgaatct gtcggtaggt cggcataggt ggcacgaatc tcggccaacg tgtgagtgcg
    19321 ttcgatggct accggatagg ggtcataccc ctctgccaat aaccgagcac gcttgtcccg
    19381 acggattcgg aactgctcgg gaatgtctga ctcggcggag ctcacgacgt gccagcttaa
    19441 atgaactcgc ctgagcactc atcgcgcggg caccgggcgc gcgaaacccg ccctaaagat
    19501 tgctcccgac cggaatcggc cgggacgcat ggtcgccggg gggcggctag cgcgccggct
    19561 tcagccgacc gcgctgagcc tcccgattgc gctcgaagac cagccgtaat ccatgcaggg
    19621 tcaggtgctc gtcgaagtgt tcgacgctgt gcagttcggg cagcagcagc ggcgcggtgt
    19681 gcccggtcgc caccaccgcg acatcgtcgt cggctgaaaa acccttaacg tcctcacgaa
    19741 tccgcgccac caggccgtca accagcccgg caaaaccgaa taccgcacca gcctgcatgc
    19801 attccaccgt gttcttaccc accaccgagc gcggccgggc caactcgacg cgccgaagtg
    19861 ccgccgaacg ggccgcggcg gcatccgaag aaacctgaac gccgggtgcg atcgccccgc
    19921 ccaggaattc gcctttggcc gacaccacgt ccacgcatat cgatgatccg aaatcgacga
    19981 caatggccgc ctttgcgaac tgctgatatg ccgccagaca gttgacgatc cggtcggcac
    20041 ccacttcttt ggggttgtcg accagcagcg gaataccggt gcgtacccca ggttcgatca
    20101 gcacgtgcgg gaccgacggc caatactgct ccagcatgat ccgcacctca tgcaacaccg
    20161 acgggaccgt ggacaacccg gtcgcaccgg tgagccgctc ggaatcctcg ccgatcaacc
    20221 cgtcgatcgt cagcgccaat tcatcggcgg tgacttcgga ttcggtccgt atccgccatt
    20281 gctgcacgac ctttgcgtgc tgtttggccc ccgatagcag accgacaacg gtgtgggtgt
    20341 tgcggacgtc gatcgccagc agcacggtta ccgcgcaccg atccgcggat tcaacagctc
    20401 ctccgccccg ggaatgtcga atgcgggcac aaaagccggg tcgtggccca cgtcgatctg
    20461 cttgttgtca gcgtcgacga acacgatccg cggctggtag gcgcgtgcct cggcatcctg
    20521 catggtcccg taggcgatca ggatcaccag atcgccgggg tgtacgagat gcgccgcggc
    20581 accgttgatc ccgattacgc cactaccgcg ttcgccggtg atcgcatacg tgaccaagcg
    20641 agcaccgtta tcgatgtcga cgatggtcac ctgttcacct tcgagcagat ccgcggcgtc
    20701 catcaggtcg gcatcgatgg tcaccgaccc gacgtagtgc aggtcggcct gcgtgacggt
    20761 ggcgcggtga atcttcgact tcaacattgt ccgtaacatc aattcctcca aggtgattgg
    20821 acacgcccgt ccggcccgac aggctgcccg tcggtaccgg cgatactttc gatctcaatt
    20881 gccacgttgt cgagcagccg ggtggtgccg aaccggacgg cgaccagcaa ccg
//
