LOCUS       NC_010612              24356 bp    DNA     circular CON 17-DEC-2024
DEFINITION  Mycobacterium marinum M, complete sequence.
ACCESSION   NC_010612
VERSION     NC_010612.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium marinum M
  ORGANISM  Mycobacterium marinum M
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
REFERENCE   1  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Davies,J.K.,
            Johnson,P.D., Abdellah,Z., Arrowsmith,C., Chillingworth,T.,
            Churcher,C., Clarke,K., Cronin,A., Davis,P., Goodhead,I.,
            Holroyd,N., Jagels,K., Lord,A., Moule,S., Mungall,K.,
            Norbertczak,H., Quail,M.A., Rabbinowitsch,E., Walker,D., White,B.,
            Whitehead,S., Small,P.L., Brosch,R., Ramakrishnan,L.,
            Fischbach,M.A., Parkhill,J. and Cole,S.T.
  TITLE     Insights from the complete genome sequence of Mycobacterium marinum
            on the evolution of Mycobacterium tuberculosis
  JOURNAL   Genome Res 18 (5), 729-741 (2008)
   PUBMED   18403782
REFERENCE   2  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Pidot,S.J.,
            Davies,J.K., Small,P.L.C., Johnson,P.D.R., Brosch,R., Cole,S.T.,
            Ramakrishnan,L. and Parkhill,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2007) Pathogen Sequencing Unit, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000018345.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,598
            CDSs (total)                      :: 5,546
            Genes (coding)                    :: 5,407
            CDSs (with protein)               :: 5,407
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 53 of 139
            Pseudo Genes (incomplete)         :: 113 of 139
            Pseudo Genes (internal stop)      :: 14 of 139
            Pseudo Genes (multiple problems)  :: 34 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5847599
            Orig. end                         :: 5871955
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000854.1.
            DNA and bacteria are available from Dr Lalita Ramakrishnan,
            lalitar@u.washington.edu.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24356
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24356
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24356
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14356](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14356
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1255..1270)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            1316..1597
                     /locus_tag="MMAR_RS24030"
                     /old_locus_tag="MMAR_4794"
     CDS             1316..1597
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020729466.1"
                     /locus_tag="MMAR_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4794"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_011738710.1"
                     /transl_table=11
                     /translation="MAEPGMVTIYLDRRRASVPLVPGETLLESARRAGLDPPFNCEAGN
                     CGTCLARLTEGSATMLVNDALDDSEVADGYILTCQGIPDTAPITVRYE"
     gene            complement(1627..2616)
                     /locus_tag="MMAR_RS24035"
                     /old_locus_tag="MMAR_4795"
     CDS             complement(1627..2616)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396331.1"
                     /locus_tag="MMAR_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4795"
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_049785316.1"
                     /transl_table=11
                     /translation="MLAGPYATLLLADLGAEVVKIEPPGGEISRTVGESYFASLNRNKS
                     GLCLDLNSEVGQHRLAELAAESDALVVNLRPSSIRRLGLTYEALRRFNERIVCVAITGY
                     GLHGGDDPAFDYVIQAAAGSAALTGEPGGPPTLPGYSSADNSTGMCAALGLLAAIISGR
                     GGQVDVSLFDVMVSQLNYHAAAYLNDGTEPQRRPHGAHPYYVPAQLFPTADGYLGLFVT
                     HDGFWKAFAAEAGIHGFETMAERASRRAEVLTVVASALATDTAAGWERRLRPLGVPAAA
                     VRTLPEALAENPQVIVRAGELRLVGNPIRVSGYRPEYRPAPLLGEHCR"
     gene            complement(2664..3620)
                     /locus_tag="MMAR_RS24040"
                     /old_locus_tag="MMAR_4796"
     CDS             complement(2664..3620)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632694.1"
                     /locus_tag="MMAR_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4796"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_012396332.1"
                     /transl_table=11
                     /translation="MRVGVMIGPERGDSGRKVGRMLADIDWAETAGLDSAWIPQIPNDF
                     DALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALSVHAATGGRLVLGVGPSHHWI
                     VDDMLGLPYQRPAAYTRDYLEVLAAALANPGPVDVENDSFRVHNPLDLAAVAPLPVLVA
                     ALGPVMLTLAGERADGTVLWMADERAVAEHVVPRISKAADNAGRPAPRIVAGIPVCLCG
                     SSEVEVARDRANRILGEAEVSPNYQRLLGYGDAKDVGDICAAGDEDAILARFRRFAEAG
                     VTDLSVRLLPIGDNREELVASKRRTRDMIATLATEVR"
     misc_feature    complement(3111..3113)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3605..4042)
                     /locus_tag="MMAR_RS24045"
                     /old_locus_tag="MMAR_4797"
     CDS             complement(3605..4042)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011738713.1"
                     /locus_tag="MMAR_RS24045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4797"
                     /product="cobalamin B12-binding domain-containing protein"
                     /protein_id="WP_012396333.1"
                     /transl_table=11
                     /translation="MAARILVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDI
                     ASIAVQEDVAVVGLSILSGAHLALTARTIEALRDADAADIAVVVGGTIPHSDVPKLLAA
                     GAAAVFPTGTPLDDLVRDIRALTGAAPTAPQPSMEEPCVSE"
     gene            complement(4043..5620)
                     /locus_tag="MMAR_RS24050"
                     /old_locus_tag="MMAR_4798"
     CDS             complement(4043..5620)
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007168510.1"
                     /locus_tag="MMAR_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4798"
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="WP_012396334.1"
                     /transl_table=11
                     /translation="MDDVTQTASGIPVAPVYGPGDRTAEPPPPGEYPFTRGNFASGYRG
                     KLWTFRQYSGFGTAEESNRRYRYLLDQGGTGLSVALDLPTQCGFDSDDPDVAEEVGRVG
                     VAVDTLADAEILFQDIPLDKISTSFTINGTAAILLAFYVAAAERKGVPRAKLTGTIQND
                     ILKEYASRGTWIWPPGPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGATAVQEMAF
                     TLADGITYCDTVVARGRMSIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATLVRERY
                     GAKTDKAAMFRFGCVCGGASLYAPQAQNNLIRVAYEAMAAVLGGVQSMFTAAWDEPFAL
                     PTEESTTLALRTQQILAYESGVTRVADPLGGSYFVEALTDATEARIIEIMDDLQRHGGM
                     VSAIEDGYLQGLIADEAFRTHKDIEAGVRPVVGVNRFVSGDAEPDIVTYELDAEGRDLQ
                     LKRLAKVKAERDSDAVQSSLAALARGAEGADNLMHRLIDCANAYCTVGEMVCALKAVWG
                     EFQQPVVF"
     misc_feature    complement(5390..5392)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5580..5593)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    5650..5668
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.33"
                     /tool="antismash"
     gene            complement(5745..6557)
                     /locus_tag="MMAR_RS24055"
                     /old_locus_tag="MMAR_4799"
     CDS             complement(5745..6557)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (41-141). E-value: 1.4e-08. Score:
                     25.1. Matches aSDomain: nrpspksdomains_MMAR_RS24055_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396335.1"
                     /locus_tag="MMAR_RS24055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4799"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_012396335.1"
                     /sec_met_domain="PCMT (E-value: 8.7e-07, bitscore: 27.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDERRAVYTHGHHESVLRGHRQRTVANSAGYLSPHLRAGLSVLD
                     IGCGPGTITVDLAARVAPATVTAVEPTDAALNLARAEVQRCDVSNVAFVTSDVHALDFP
                     DDVFDVVHAHQVLQHVADPVQALREMKRVCAPGGLVAARDADYAGFIWYPQLPALDHWL
                     KLYQRAARANGGEPDAGRRLLSWARQAGFADITPTGSMWCYATDEMRAWWGGMWAERIL
                     RSDLSAQLLGSGMASAADLEAISQAWRDWAAAPDGWLGIPNGEILCRV"
     aSDomain        complement(6135..6434)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS24055_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.40E-08"
                     /label="MMAR_RS24055_oMT.1"
                     /locus_tag="MMAR_RS24055"
                     /protein_end="141"
                     /protein_start="41"
                     /score="25.1"
                     /tool="antismash"
                     /translation="SVLDIGCGPGTITVDLAARVAPATVTAVEPTDAALNLARAEVQRC
                     DVSNVAFVTSDVHALDFPDDVFDVVHAHQVLQHVADPVQALREMKRVCAPGGLVA"
     gene            complement(6618..7403)
                     /locus_tag="MMAR_RS24060"
                     /old_locus_tag="MMAR_4800"
     CDS             complement(6618..7403)
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016805 - dipeptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008253538.1"
                     /locus_tag="MMAR_RS24060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4800"
                     /product="M15 family metallopeptidase"
                     /protein_id="WP_012396336.1"
                     /transl_table=11
                     /translation="MRRVGAAAALVACGVACGITAAPSGVWTSPGGSSIPSPPVVTSAV
                     RAVATTASVPAGSVPPVSAAAAAAGLVDVRSVVPDAIIDLRYATTNNFTRTQLYPADAR
                     CLVHESMAPGLTAAAAALRPQGQALVFWDCYRPHDVQVKMFQVVPNPAWVARPGQYARS
                     HEAGRSVDVTYASVSPQCPPQRQISGICLADMGTDFDDFSARAKAFATEGVSEAAQAGR
                     KRLRDAMNYGGLSVYSGEWWHFDGPGAGVDRPILNAPVD"
     gene            complement(7511..7813)
                     /locus_tag="MMAR_RS30650"
     CDS             complement(7511..7813)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015357221.1"
                     /locus_tag="MMAR_RS30650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_036450556.1"
                     /transl_table=11
                     /translation="MNAIAHRQHAGHDHSHGDGCGHVAIPHGDHVDYLHDGHLHRRHGD
                     HFDECEPGDGHCVHDGHDHTHGDGCGHVAVPHGDHVDYIHDGCRHAAHDGHYDEH"
     gene            8126..8980
                     /locus_tag="MMAR_RS24070"
                     /old_locus_tag="MMAR_4802"
     CDS             8126..8980
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396338.1"
                     /locus_tag="MMAR_RS24070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4802"
                     /product="cellulose-binding domain-containing protein"
                     /protein_id="WP_012396338.1"
                     /transl_table=11
                     /translation="MSDENRNERHRRPALHAVVAAFVLVCSAFLAAPTAHAAAITATLA
                     VTSQWDTGFVANYRIANPGATELADWKLEFDLPAEESVTNSWSSKLAQSGTHYVLTPEE
                     YNRTIAPEHSISIGFQATLDGEFSAPQNCVLNGESCTSAPDLAPATATAPTPTTAPASA
                     PPPPSADDAAATLAVISQWNTGFVANYEIANTGSTALDGWKLEFDLPADESVTRAWSSK
                     LSKTGTHYVLTPESYNTTIAPGSSVTVGFQAAQTSTYSAPANCQLNGESCGDGPAPTAS
                     VRH"
     gene            complement(8999..9289)
                     /locus_tag="MMAR_RS24075"
                     /old_locus_tag="MMAR_4803"
     CDS             complement(8999..9289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396339.1"
                     /locus_tag="MMAR_RS24075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4803"
                     /product="hypothetical protein"
                     /protein_id="WP_012396339.1"
                     /transl_table=11
                     /translation="MTGATGRYGPISFAVALAHILVVEFATWLCVLSVPPLAVFVLLVS
                     LIYLSISSVVAKSPGKLGQVGRGMLIGTVAAPLSLAILIAAILVARLFPAG"
     gene            complement(9286..9618)
                     /locus_tag="MMAR_RS24080"
                     /old_locus_tag="MMAR_4804"
     CDS             complement(9286..9618)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015357224.1"
                     /locus_tag="MMAR_RS24080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4804"
                     /product="hypothetical protein"
                     /protein_id="WP_015357224.1"
                     /transl_table=11
                     /translation="MSFLARIRDMDATAWRSATWSAPVVIQFCLLLLLAAMWLLGKWAF
                     PTESGRSERTLLLTATALATLVSLGAGAVLLNSSSSQRRGIGLGVTGAAAVVLIGGIAF
                     AFLVLR"
     misc_feature    complement(9355..9357)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9842..9858
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    10000..10015
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            10001..11155
                     /locus_tag="MMAR_RS24085"
                     /old_locus_tag="MMAR_4805"
     CDS             10001..11155
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396341.1"
                     /locus_tag="MMAR_RS24085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4805"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_012396341.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4e-50, bitscore:
                     168.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSTRQRPTLSLATAVDSPDSGRMASTGDAVSLGDADWRSRLRTA
                     ALAQIADFVSDRSASALGGSGWEVAGDILLRFVSEGKCLRSTFMYLGWLCGAGPNNAAL
                     SAAASLELLHAFALLQDDVMDQSPQRRGSPAVHVQLARCHQRRGLSGAAARFGESAAVL
                     LGDICLVWAEQMLRESGVEDRRLRQVWPRYDAMRIELAVGQLCDLSNDIRNLPTLDAVL
                     DVARRKSGNYTVRRPLEMGAAMADCDERTLEQLARYGDAVGEAFQLRDDMLGVFGTPAI
                     TGKPSGDDLRERKATSVVVAAYEMADPPTRRQLHELMHRAELDDAAVDHCKRLITATGA
                     VQRIEDMIDRRVDRVRTLLADMTIGQQTRAALGDLAAACVQRST"
     misc_feature    10310..10312
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11180..12709
                     /gene="crtI"
                     /locus_tag="MMAR_RS24090"
                     /old_locus_tag="MMAR_4806"
     CDS             11180..12709
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020729454.1"
                     /locus_tag="MMAR_RS24090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4806"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_012396342.1"
                     /sec_met_domain="DAO (E-value: 9.3e-18, bitscore: 63.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTIEGTADHVVVIGAGLAGLATALHLAGRGRSVTVVEREAWPGG
                     RAGRLDIDGYRIDTGPTVLTMPDLIDEVFAAVGETISDRLELLPVDPAYTAMFADGSSI
                     DVHCDADRMVAAIENFAGPEQATGYLRLREWLTRLYRIEFAGFIGSNFDSPLSLLTPQL
                     ARLAAAGGFRNWDSMVKRHITDPRLRRVFTFQSLYAGVAPQDALAAYAVIAYMDTISGV
                     FFPRGGVRALPDALAAAAACAGVQFHYGSQVSELERDDARITAVRTDRGERIACDAVVL
                     TTELPTTYRLLGRTPRRLRRLRAAPSAVVVHAGCRSASTASEPAAHHTILFGQAWEQTF
                     TDIIRDGRLMRDPSLLVTRPTAGDPALAPPGRDLLYLLAPAPNLTAGRVDWGSAGGSYA
                     QSMIDTVASRLLPDLRDSVELLDVVTPLDWARQGMAAGTPFALAHTFGQTGPFRPANTV
                     RGIDNAVLAGSSTVPGVGVPTTLISGRLAADRITGNTTRSIRHLDLKAQLS"
     gene            12706..13665
                     /locus_tag="MMAR_RS24095"
                     /old_locus_tag="MMAR_4807"
     CDS             12706..13665
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785898.1"
                     /locus_tag="MMAR_RS24095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4807"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_012396343.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-113,
                     bitscore: 376.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.5e-60,
                     bitscore: 201.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRSELDAAGIGDPRLREAYQQSRRINAASGRTFFLATRLLAPDQ
                     RPPVHALYGFARYADDILDSFDPRLDTDTRAQRLQQLAQQFFSGADHPDNPVLAAVSHT
                     ARRYGIGADLFEDFLESMRMDLTITDYPDRDALNTYMRGSAEAIGLQLLPILGTVVPAR
                     EAMPYAAALGRAFQLTNFIRDVDEDLARNRIYLPADELAAYGVDRDVLMWCHHNQRSDG
                     RVREALAAQHEITRETYRFAAAGIQLLAPRSRPCVATALTLYSEILDRIEGDDFAVFGR
                     RATVGTARRLRVAGAGLIRAWRARTSDAIPDRSEYGAA"
     misc_feature    13159..13161
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13662..13985
                     /locus_tag="MMAR_RS24100"
                     /old_locus_tag="MMAR_4808"
     CDS             13662..13985
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009978288.1"
                     /locus_tag="MMAR_RS24100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4808"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_012396344.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.3e-23,
                     bitscore: 81.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRWQYLLVLLACLAITAPLEVFGAGVYRRPRRLLRSVLPVAAA
                     FLVWDELAVAARVWTYDPRYISGLNVPFQVPIEEVLFFLVIPICALLTLNAVSTILDRL
                     RRR"
     gene            13982..14356
                     /locus_tag="MMAR_RS24105"
                     /old_locus_tag="MMAR_4809"
     CDS             13982..14356
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003889219.1"
                     /locus_tag="MMAR_RS24105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4809"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_012396345.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 2.9e-21,
                     bitscore: 74.1, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLGYTLPAVLAVAGVGALELLVLRTGLFRRPAYWLSMVIVLGF
                     QVPVDGWLTKLSAPIVSYNERQITGLRFPFDIPIEDFLFGFAMVTAVLLLWERQREPGE
                     PAPPSQAGCHEKHSLEDKTC"
     gene            14350..16659
                     /locus_tag="MMAR_RS24110"
                     /old_locus_tag="MMAR_4810"
     CDS             14350..16659
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785895.1"
                     /locus_tag="MMAR_RS24110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4810"
                     /product="MMPL family transporter"
                     /protein_id="WP_012396346.1"
                     /transl_table=11
                     /translation="MLTRMARLSLSAPRRVIAVVVLVMIGTAIFGIPAANSLAAGGFLD
                     PSSESARAAAVLADKFHRGDMEMVLLVSSDDGVRDGPARIVGTDIARQLAQSPFVAQVA
                     SPWDTPQPPPDMLSADGKSALILVALKGDENSAPRHAQALAQRLAHDRGGVTVQAGGSA
                     MVYAQVNQQTEKDLLRMEFIAVPVSFAALVWVFGGLLAAALPVAVGGFAILGSLAVLRG
                     VAMVTDVSIFALNVTVALGMALAIDYTLLIIRRYRDELGEGRSHEDALVRTMTTAGRTV
                     LFSAVTVGLSLVAMALFPMYFLKSFAYAGVAVVAFSALAAMVVAPTVIVLLGDRLDALN
                     VWKLGRRLLGRPEPPPRPVAQSFWYRTAKLVTRHAIPVGLAIIVLLIALGIPFLNIKWG
                     YPDDRVLPPSASARMVSDRIRSDFGSNSASRVTVVITDTAGLTKPDLNHYAAQLSEVSD
                     VSAVSAPTGTFVAGELRGPPSAPTAMAAGSAYLTVESTAPLYTKASANQLDRLHAVALP
                     GDTAVQMTGVAQMNRDSVNGITSRLPMVFGFIAIVTLVLLFLLTGSVLLPIKAVVLNML
                     SLTAAFGALVWIFQDGHLGALGTTPTGTLVANIPVLMFCIAFGLSMDYEVFLLSRIREF
                     WLGSPQQSADNDESIALGLAHTGRVITAAALLMSISFAGLISAEVSFMRMFGVGLTIAV
                     LVDATLVRVLLVPAFMHVFGGLNWWAPKPLERWHSRSGADRSAGQTGPSDGAVGGNSSK
                     FDSNRRVDDHVHRSPR"
     gene            16709..17260
                     /locus_tag="MMAR_RS24115"
                     /old_locus_tag="MMAR_4811"
     CDS             16709..17260
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396347.1"
                     /locus_tag="MMAR_RS24115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4811"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_012396347.1"
                     /transl_table=11
                     /translation="MTKRVAVNRQPSRAELERLLSADLRAITAHSDRVGRYYARHNDLS
                     HGDFQALLHIMVAETAGTPVTPAQLSQRLDVSAAAITYLADRMIHAGHIRREADPDDRR
                     KSHLRFEQSSLELAHKFFMPLGDHMREAMADLSDRDLRAAHRVLTAMMDGMETFEKELY
                     ESPAPTSGRPRKTPAQAESP"
     misc_feature    16766..16768
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17270..18316)
                     /gene="fni"
                     /locus_tag="MMAR_RS24120"
                     /old_locus_tag="MMAR_4812"
     CDS             complement(17270..18316)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785894.1"
                     /locus_tag="MMAR_RS24120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4812"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_012396348.1"
                     /transl_table=11
                     /translation="MTNDPAEISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQ
                     TSLADIDLSAEFFGAPLRAPVLIGAMTGGAELSATINRNLATAAQRLGIGMMLGSQRIM
                     LDDARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAALRRVGANALAVHANS
                     LQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLKEVGHGIGAAAVAQLLRLPGGLPVSG
                     IDVAGAGGTSWSRVEQLVRYGELRYPELADWGIPTAEAIVEVRQALPAVPLVASGGIRT
                     GMDAAKAIALGADVVAIARPLLAPAIESATAVQGWLQLFLDELRVCLHCCGARDLTSLR
                     DIGVTAIR"
     gene            complement(18433..19140)
                     /locus_tag="MMAR_RS24125"
                     /old_locus_tag="MMAR_4813"
     CDS             complement(18433..19140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396349.1"
                     /locus_tag="MMAR_RS24125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4813"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_012396349.1"
                     /transl_table=11
                     /translation="MVADLGEPNRPLSGGRVWTWKWPETLSARGWQWCRVYHLSAHTPD
                     AITHRAFGPLHRLDHHTPPAAHPAICPEGRSVLYVAGTLATALGEVFGDLGEAAVCPRF
                     RVGLLRPRTEIVVLDLRSEGAAMRIGALPSLATGAYPRVRTQAWARAIYEDQPARRPVH
                     GVYYHAAHSNGRALALWDTDGAVDQVRTRARQRQDFALADAAIWPRVLVAAAELAMTAA
                     RVDSCPLCDISAT"
     gene            complement(19134..19736)
                     /locus_tag="MMAR_RS24130"
                     /old_locus_tag="MMAR_4814"
     CDS             complement(19134..19736)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020729446.1"
                     /locus_tag="MMAR_RS24130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4814"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_012396350.1"
                     /transl_table=11
                     /translation="MVTRTPTRKAAPRRRQRASASAAQLSSAVHAVLDAAPASVKAGFV
                     EAVAARDTGGLDESLWGSAPTAKEMSSAALQALQDDFVARRELLTMSLSTAEVAELLDI
                     SSQAVLDRITGGDLIGLKDGRQWRIPMWQLNAGAQRGFLSGIAELRQAFPGGIVALSKW
                     AATPNPELGDITPADALAAGRVDDVIAVVAKSTAAAW"
     gene            complement(19818..21302)
                     /locus_tag="MMAR_RS24135"
                     /old_locus_tag="MMAR_4815"
     CDS             complement(19818..21302)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011738728.1"
                     /locus_tag="MMAR_RS24135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4815"
                     /product="amino acid permease"
                     /protein_id="WP_012396351.1"
                     /transl_table=11
                     /translation="MRTPSSPTHPDDIALASEDAGYHKSLKPRQLQMIAIGGAIGTGLF
                     LGAGGRLASAGPALFLVYAVCGVFAFLILRALGELVLHRPSSGSFVSYAREFFGEKAAY
                     VAGWMYFLNWAMTSIVDSTAIATYFHFWRVFEGIPQWALALFALGIALSMNLISVTLFG
                     EIEFWAALIKVVSLLTFLVVGTIFLAGRYPVDGHSTGLGLLAHGGGLFPYGLLPLVVVT
                     SGVVFAYAAVELVGTAAGETAEPEKVMPRAINSVIARIALFYVGSLFLLGLLLPYTDYK
                     AGESPFVTFFDKIGVTGAGSIMNVVVMTAAFSSLNAGLYSTGRILRSMAMNGSAPSFTA
                     RMSQRGVPYGGICLTAAIGLIGVLLNGVVPEMAFEIVLNIAALGILASWATIVCCQIQL
                     FRWSKQGIVYRPSFRMWGAPYTGYLTLVFLFAVLVLMGFSYPIGTWTVATLGLIIPMLI
                     GGWFLVRDRVLEIARRRIGYTGEFPVVANPGPMDKK"
     gene            complement(21346..21588)
                     /locus_tag="MMAR_RS24140"
                     /old_locus_tag="MMAR_4816"
     CDS             complement(21346..21588)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396352.1"
                     /locus_tag="MMAR_RS24140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4816"
                     /product="hypothetical protein"
                     /protein_id="WP_012396352.1"
                     /transl_table=11
                     /translation="MRFVDFKAKTPLIGMSMVFGAMALVAVTAYLHAGWYSIIGYAIAA
                     AVAAFGFIFTFRDIPTPPHTPGPDDPAGSEPAPGG"
     gene            complement(21778..22338)
                     /locus_tag="MMAR_RS24145"
                     /old_locus_tag="MMAR_4817"
     CDS             complement(21778..22338)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012396353.1"
                     /locus_tag="MMAR_RS24145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4817"
                     /product="AAA family ATPase"
                     /protein_id="WP_012396353.1"
                     /transl_table=11
                     /translation="MTRRYILTGTPGAGKTSILRRLAQLGHAVVAEAATDVILGRQARG
                     EDAPWTGATKASFIDEVVETQRRRQVAADPTGPGVCFFDRSPVCTHALAVYLGLPVCAA
                     LTAELDRIAAEHTYQRQVFFVRNLGFCQPTTTRRIDMAEALRFERIHEDSYREFGYQLI
                     DIPADRLDRRVATISRMISPLAP"
     gene            22526..23464
                     /locus_tag="MMAR_RS24150"
                     /old_locus_tag="MMAR_4818"
     CDS             22526..23464
                     /NRPS_PKS="Domain: PKS_KR (7-94). E-value: 1.2e-06. Score:
                     20.5. Matches aSDomain:
                     nrpspksdomains_MMAR_RS24150_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008258457.1"
                     /locus_tag="MMAR_RS24150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4818"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_041325519.1"
                     /transl_table=11
                     /translation="MQDLQGKVAVVTGGAGGIGRALGKRFGMEGMKVVLADVLAEPLDR
                     ATRALTDEGIEAVGVVTDVTDYSSVEALAKETLHRFGAVHVVCNNAGTGGVSEGYMWEH
                     DLADWHWGIDVNVVGVIHGIKAFVPILLERGEGHVVNTCSGNGGFAPIARGAMGGPAMA
                     VYPMTKAAVLCLTESLYTHLEMTGTRVRAHALFPGGFLNTGIWESWRHRPQRYAATQTR
                     RTPEHTLADVVGRFEAAGARVEFTPLAAVADQVVEGIRADRFWMMGPPTPADEVVTRKA
                     ASIVARADPDYLVDVLGRSAAKEPETEGGKR"
     aSDomain        22547..22807
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS24150_PKS_KR.1"
                     /evalue="1.20E-06"
                     /label="MMAR_RS24150_PKS_KR.1"
                     /locus_tag="MMAR_RS24150"
                     /protein_end="94"
                     /protein_start="7"
                     /score="20.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGGAGGIGRALGKRFGMEGMKVVLADVLAEPLDRATRALTD
                     EGIEAVGVVTDVTDYSSVEALAKETLHRFGAVHVVCNNAGTG"
     CDS_motif       22553..22594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MMAR_RS24150_0001"
                     /evalue="5.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="MMAR_RS24150"
                     /protein_end="23"
                     /protein_start="9"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VVTGGAGGIGRALG"
     gene            23461..24276
                     /locus_tag="MMAR_RS24155"
                     /old_locus_tag="MMAR_4819"
     CDS             23461..24276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014385355.1"
                     /locus_tag="MMAR_RS24155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_4819"
                     /product="acetoacetate decarboxylase family protein"
                     /protein_id="WP_012396355.1"
                     /transl_table=11
                     /translation="MITNAVRYGPRPPEAQVDHEIDATKAPIATEAVTVTYLTDPQIVA
                     AVLPKPLQPADEPLVRVQLQRVQIAGRPPFGSAVFAVTARHGDLQGDYPLFMPQSTEQS
                     VTGGRETFGEPKKLAHIEVDHDGSRVSATVDRMGYRLITVSGQVSGGAPLPPDQVNTEF
                     YFKFLRSPDGNGITDPHLVYGEYHRHYELLENIDGSLELGESPLDPVADIVIRQIRSIT
                     WCRRRTIQVGRIATRVPQEWLLPYVHQRYDEPHDAPAPATPPSPEPARA"
ORIGIN
        1 cccgtccggc accccgaaca ccgcacaatc ccggaccgcg ggatggccgt gcagaaccgc
       61 ctcgatctcg gcgggggcga cctggaaacc gcgaaccttg atcatctcct tgagccggtc
      121 ggtgacgcgc agccagccgg cggcatccag cgagccgatg tctccggtcc gataccaacc
      181 ctgcgacatg acctcggccg tggcggccgc cggcagatag cccgccatca gtgaatgcga
      241 tcgcgcctgg atttcgccga cctcaccggg gcccacccgc tcaccggttt cgatcgacac
      301 cacccgcagg tccacgcccg gcagcacacg tccgacggtg tcgagccggg cgccccgcag
      361 cgggctgcag gcgatcacgg gtagctcggt ggtgccgtag gcgggcaccc agccaatgcc
      421 ggtccggttc gtcaccgtct cggcgatgcc cgcactcacg ggcgtggcgc cccacatgat
      481 gaacctcagc gacgacaaat cgtaggactc gaggttggga tgcgacgcca tcgccaaagc
      541 tatgggggcg accgccattt ccacggtaat ccggtcgctt tcgatgtgtg ccagcatctg
      601 gtcgatgtcg aaccggcgat gcagacgcac ccgaacgccg gtccgcaacg cggtgacgat
      661 gttgagcaag ccgaggatgt gcgagggcgg cgtgacgatc tgaatgcggt cgcgctcggt
      721 cagccccagc gcgtcacgcc agtggccaat ggccgcgttc agcgacgcgt gggtgtgccg
      781 gaccgccttg ggcaggccgg tggtgcccga gctgaacacc aacagcgcat cgccagcacg
      841 gcgcggcgcg cccggtagcg gtgccgcggg ggtgatcggc tcatccaggt gcagcatcgg
      901 catcagaccg gccagcaccg ggtgatcccc ggcggcatgg gcggggccgg tcagggcgag
      961 ggcatgatcc acctcggcgc gcttccaggc ggggctgatg agcaccgccg aggcgcccag
     1021 acaccagatg gcgttcagca cggcgacaaa ctccggccgg ttggacgaca tcaccgccac
     1081 ccgatcgccc gcgacgacgc cttgcttgcg tagcgccgcg gccaggccgt cggccatcgc
     1141 ccccagcccg ggcaggctaa agccccgatc ctcgaacacg agcgcggccg gctcggtcac
     1201 gtctcgtcct tcccggcggt cacgacagtc tgagaatatc ctatctcccg atgagaatag
     1261 tattctcaat agagaagaac gcaagtacat cagtgggggc gcaggaaggg cggtcatggc
     1321 ggaaccgggc atggtgacga tctacctcga ccgtaggcgg gcatcggtgc cgctggtgcc
     1381 tggcgagacc ctgctggaaa gcgcacgacg agcggggctg gacccgcctt tcaactgcga
     1441 ggccggcaac tgcgggacct gcctggcccg cctcacggag ggcagcgcga caatgctggt
     1501 caacgacgct cttgacgaca gcgaggtggc cgacggctac atcttgacct gtcagggcat
     1561 acccgatacc gcaccgatca cggtgcgcta cgagtagacc cgcgcagcac caggatcggc
     1621 gtgccgctat cggcagtgtt cgcccaggag cggcgccggc cggtattcgg gccgataacc
     1681 ggacacccga atcggattac cgacgaggcg caattcgccc gcgcgcacga tcacttgggg
     1741 attctccgcg agggcctcgg gcagcgtccg aacggctgcc gcgggcaccc ccagcggccg
     1801 cagccgtcgc tcccaaccgg cggcggtgtc ggtcgccaac gccgaggcga ccacggtgag
     1861 cacctccgca cgccgggacg ctcgctccgc catggtctcg aagccatgga tgccggcctc
     1921 ggccgcaaag gccttccaga acccgtcatg tgtgacgaac agcccgaggt agccgtcggc
     1981 ggtcggaaat agctgcgcgg gaacgtaata cgggtgagcg ccatgaggcc tgcgctgcgg
     2041 ctcggtgccg tcgttgaggt acgcggcggc gtggtagttc agctgggaga ccatgacgtc
     2101 gaacagcgac acgtccacct gcccgccacg gcccgagatg atcgccgcca acaacccaag
     2161 cgctgcacac atcccggtgg agttgtccgc cgaggaatac ccgggcaggg tcggcggacc
     2221 gccgggttca ccggtcagcg cggcacttcc ggcggcggcc tggatcacgt agtcgaaggc
     2281 cggatcgtcg ccgccatgca acccataacc ggtgatcgcc acgcaaacga tgcgttcgtt
     2341 gaaccgccgc agcgcttcgt aggtcaaccc cagtcggcgg atcgacgacg gtcgcaggtt
     2401 gaccaccagc gcatcggatt cggccgccag ctcggcgagc cggtgctgtc ccacttcgga
     2461 attcagatcc aggcagaggc cggacttgtt gcggttgagg ctggcgaagt agctctcacc
     2521 gacggtgcgt gagatctcac cgccgggcgg ttcgatcttg acgacctcgg cgccgaggtc
     2581 ggcgagcagc aatgtggcgt aagggccggc cagcatggtg ccgacctcga tgacccgaat
     2641 gccggtcagc gggcccgcgg cggtcaccgc acctccgtcg ccagcgtggc aatcatgtct
     2701 cgggtgcgac gcttggaggc aaccagctct tcacgattgt cgccgatcgg cagcaggcgc
     2761 accgacaggt cggtcacacc ggcctcggcg aagcgacgga atcgagccag gatcgcgtcc
     2821 tcgtcgccgg ccgcacagat atcaccgacg tctttggcat cgccgtatcc gagcagtctt
     2881 tgatagttcg gcgaaacctc ggcctccccc agaatccggt tggcgcgatc acgcgctacc
     2941 tcgacttcac tcgagccgca aaggcaaacg gggatgccgg cgacgatgcg cggagccggg
     3001 cgaccggcat tgtcagcggc cttggagatt ctgggcacca catgctcggc caccgcacgt
     3061 tcgtcggcca tccacagcac ggtgccgtcc gctcgctcgc cggccagggt taacatcacc
     3121 ggcccgagcg ctgcgaccag caccggcagg ggcgccaccg cggccagatc cagcgggttg
     3181 tgcacccgga agctgtcgtt ctccacgtcg acgggcccgg ggttggccaa ggccgcggcc
     3241 aggacctcga ggtagtcccg ggtgtaggcg gcgggccgct ggtagggcag cccgagcatg
     3301 tcgtcgacga tccaatggtg cgacggtccg acgcccagca ccaggcgacc accggtggcc
     3361 gcatgcaccg acagagcttg ccgggccaac gcaatcgggt gctgcgtctg caggggcaca
     3421 acggcggtac ccagctcgat gcggctgctc cgcgttccca tcagggtcac ggcgaccagt
     3481 gcgtcaaagt cattgggaat ctggggaatc cacgcgctat ccaggccggc tgtttccgcc
     3541 cagtcgatat cggccagcat ccggcccacc ttgcggcccg aatccccgcg ctcggggccg
     3601 atcatcactc cgacacgcac ggttcctcca tggacggttg cggtgcggtg ggcgcggcgc
     3661 cggtcagcgc gcggatgtcg cgcaccaggt catccagcgg tgttccggtg ggaaacaccg
     3721 ccgccgcacc ggcggccagc agcttgggca cgtcggagtg cgggatggtc ccgccgacga
     3781 cgacggcgat gtcggcggca tcggcgtcgc gcagggcctc gatggtgcgt gccgtcaggg
     3841 ccagatgggc acccgacaag atgctcaagc cgaccacggc cacatcttct tgaacggcga
     3901 tcgaggcgat gtcttcgata cgttgccgga tgccggtgta tatcacctcg aagccggcgt
     3961 cgcgcagcgt gcgggccacg atcttggcgc cacggtcatg accgtcgaga ccgggcttgg
     4021 cgaccaggat ccgggcggcc atctagaaca ccaccggttg ctggaattcg ccccacaccg
     4081 ccttgagggc gcagaccatc tcaccgaccg tgcagtatgc gttggcgcag tcgatcagcc
     4141 tgtgcatcag attgtcggct ccttcggcgc ctcgcgcgag cgctgcgagg ctggactgca
     4201 ctgcgtcgct gtctctttca gccttgacct tggcgagccg cttgagctga aggtcacggc
     4261 cttcggcgtc gagttcgtag gtgacaatgt cgggttcggc gtccccggag acaaacctgt
     4321 tgacccccac gacgggtcga acacccgctt cgatgtcctt gtgcgttcgg aaggcctcgt
     4381 cggcgatcag gccctgcaga tatccatcct cgatggcgct gaccatcccg ccgtggcgct
     4441 gcaggtcgtc catgatctcg atgatccgag cctcggtggc atcggtgagc gcctctacga
     4501 agtaggagcc gccaagcggg tcggcgacgc gggtcacgcc gctttcatag gccaggatct
     4561 gctgggtgcg cagcgccaac gtggtggact cctcggtcgg cagggcaaac ggctcgtccc
     4621 aggccgcagt gaacatcgac tgcaccccgc ccaacaccgc ggccatcgcc tcgtaggcga
     4681 cgcggatcag gttgttctgc gcttgcggtg catacagcga cgcgccgccg cacacgcagc
     4741 cgaaccggaa catcgccgct ttgtccgtct tggcgccgta tcgctcgcgc accagcgtcg
     4801 cccagcgccg tcgtcccgca cggtatttgg cgatctcctc gaaaaagtcg ccgtgggtgt
     4861 agaagaagaa cgagatctgt ggggcgaact gatcgatgga catccgaccg cgtgcaacga
     4921 cggtgtcgca gtaggtgatt ccgtcggcga gggtgaatgc catctcctgt accgcggtgg
     4981 ccccggcgtc acgaaaatgg gctcccgcca ccgatatggc gttgaatttc gggacctcgg
     5041 ccgcacagaa ctcgatcgtg tcggcgatca gccgcagcga gggccccggc ggccagatcc
     5101 aggtcccgcg cgacgcgtac tccttgagga tgtcgttctg gatcgtcccg gtgagcttgg
     5161 cgcgcggaac tccctttcgc tcggcggcgg ccacgtagaa cgccagcagg atcgccgccg
     5221 tgccgttgat ggtgaaactg gtgctgatct tgtccagggg gatgtcctgg aacaggattt
     5281 cggcgtcggc cagggtgtcg accgcgacgc cgacgcggcc gacttcctcg gcgacgtctg
     5341 ggtcgtcgga gtcgaatccg cattgggtgg gcaggtcgag cgccaccgat aacccggtcc
     5401 cgccctggtc cagcagatag cggtagcggc ggttggactc ctcggcggtg ccgaacccgg
     5461 agtactgccg aaacgtccac aacttgcccc ggtatcccga cgcgaagttg ccgcgggtga
     5521 aggggtactc ccccggaggc ggcggctccg ccgtgcggtc cccagggccg tagaccggcg
     5581 caactgggat gcccgatgca gtctgggtca catcatccat cgatgaataa cgtacttgca
     5641 aaaaaagaga atgccaatac cactcagttg accagcataa acgggctcag agcgaggggg
     5701 ttccagagcc ggtcggggtg cgcggcttcg acagggcgcg gcggctacac ccggcagaga
     5761 atttcgccgt tgggaatccc cagccaacca tccggtgccg cggcccagtc ccgccaagcc
     5821 tgcgaaatcg cctccagatc tgcggcgctg gccatcccgg agcccagcag ttgggcagac
     5881 agatccgaac gcagaatccg ttcggcccac attccgcccc accaggcacg catctcgtcg
     5941 gtcgcgtagc accacatgct gccggtcggc gtgatgtcag caaagcccgc ctgacgagcc
     6001 cacgacagca gccgccggcc ggcatcgggc tcaccgccgt tggcacgcgc cgcccgctga
     6061 tagagcttta gccaatggtc caaggccgga agttgcgggt accagatgaa ccccgcgtag
     6121 tcggcgtcac gcgcggcgac cagcccgccg ggcgcacaga cgcgcttcat ctcccgcagc
     6181 gcctgcaccg gatcggccac gtgctgcagc acctggtggg catggactac gtcgaacacg
     6241 tcatcgggaa agtccagggc atgcacatcg gaggtcacga acgcgacatt ggacacgtcg
     6301 catcgctgca cctcggcacg ggccaggttc agcgccgcat cggtgggctc caccgccgtc
     6361 accgtagcgg gcgccacgcg cgccgcgagg tcgacggtga tagtcccggg gccgcaaccg
     6421 atgtcgagca cggacaaccc cgcacgaaga tgcggcgata ggtagccggc ggagttggcc
     6481 accgtgcgct gacggtgccc acgcagcacc gactcgtgat gcccatgggt atagacggct
     6541 cggcgttcgt cgttcatgaa ccggagccta cccgcctaaa tcaaaaagtg agacagctat
     6601 ctcactatat gagacagtca gtcgaccgga gcattgagga tcggccggtc gacccccgcc
     6661 cccgggccat cgaagtgcca ccactcaccg gagtacacgc tcaacccgcc gtagttcatc
     6721 gcgtcgcgca gccgtttacg gccggcttgg gccgcctcac taaccccttc ggtggcgaat
     6781 gccttggccc gcgccgagaa gtcatcgaag tcggtgccca tgtcggccag gcagattccg
     6841 ctgatctgcc gctggggcgg gcattgtggc gacacgctgg cataggtcac gtcaaccgag
     6901 cggcccgcct cgtggctgcg ggcgtattga cccggacgcg ccacccaggc cgggttcggg
     6961 accacctgga acatcttgac ctggacatcg tgcggtcggt agcagtccca gaacaccagc
     7021 gcctgccctt gcgggcgcag cgccgccgcg gcggccgtca accccggcgc catcgattcg
     7081 tgcaccagac atcgggcatc ggcgggatac agctgcgtgc gggtgaagtt attggtggtc
     7141 gcgtagcgca ggtcgatgat ggcgtcggga acgacactgc gcacatcgac aaggccggcc
     7201 gcagccgcgg cggcactgac cggcgggacg gacccggccg gcacgctggc cgttgtcgcg
     7261 acggctcgca cggccgaggt gaccaccgga ggcgatggga tcgatgaccc gccgggactc
     7321 gtccacacac ccgacggcgc ggcggtgata ccgcaggcca caccgcaggc gacgagggca
     7381 gcggcggcgc caacccttcg caatgggccg ctatggagtg catcggcaat actgctcacc
     7441 gcaccgaggc tacgtcgggt cagcccgttc tcacgtttat cgccgacggt gttcggcgat
     7501 cagcggccga tcaatgttcg tcgtagtgcc catcgtgggc ggcatgccgg catccgtcat
     7561 ggatgtagtc gacgtgatcg ccgtggggaa cggcgacgtg gccgcagcca tcgccgtgag
     7621 tgtgatcgtg cccgtcatgc acgcagtggc cgtcgccggg ttcacattcg tcaaagtgat
     7681 cgccgtggcg ccggtgcaga tgaccgtcgt gcagatagtc gacgtgatca ccatgcggaa
     7741 tcgcgacatg tccgcaaccg tcgccatgcg aatggtcgtg ccccgcgtgc tgccggtgcg
     7801 ctatcgcgtt catctctttc tccttgtgat tgttgagcgg gccgggaatg tcgacatgtc
     7861 gggcgcgtca gcggacttgt cggtcgcggt cgagctgtcg acaccaccat tcaatcctca
     7921 accagccatc acgggggaca agagcagaaa gtcaccgaaa actcttggat ccagtgtctt
     7981 cgagccaacg gacatcgcac gccgccggcc agccagccaa caacaaaggc gcaagatttc
     8041 gccggggttt cggttgggcg aagataccgc agctttcaaa caccgccatt acatatgttg
     8101 ctaatcgaac tataccgttg gcgcgatgtc cgacgagaat cgcaacgagc gccaccggcg
     8161 ccccgcgctt cacgctgtcg tcgcggcatt tgtcctggtc tgctccgctt ttctcgccgc
     8221 ccccaccgca cacgcggcag cgataaccgc aacgctggcg gtgacgtcac aatgggacac
     8281 cggcttcgtc gccaactacc ggatcgccaa tcccggcgcg accgagttgg cggactggaa
     8341 gctcgaattc gacctgcccg ccgaggaatc tgtgacaaat tcgtggagca gcaagctggc
     8401 ccaatcggga acgcattacg tcctaacacc cgaagagtac aaccgcacca tcgcgccgga
     8461 gcactccatc agtattggct ttcaggccac gctagacggc gaattctcgg ccccacagaa
     8521 ctgtgtgctc aacggcgagt cctgcaccag tgcgccggac ctagcgccgg ccacagccac
     8581 cgcgcccaca ccgaccaccg cgccggccag cgcgccgcca cccccgtccg ccgacgacgc
     8641 ggcggcaaca ctggcggtga tctcacaatg gaataccggc tttgtcgcca actacgaaat
     8701 cgccaatacc gggtccacag ccctggatgg ctggaagctc gaattcgatc tgcccgcaga
     8761 cgaatccgtc acccgagcgt ggagcagcaa actctccaag accggcacgc actacgtcct
     8821 gacaccggag tcctacaaca ccaccatcgc ccccggcagc tcggtcaccg tcggtttcca
     8881 ggccgcccag accagcacgt attcggcgcc tgcgaattgt cagctcaacg gcgaatcttg
     8941 cggcgacggt ccggccccta ccgccagcgt gcgccactga cgacgccggt cgcgggcgct
     9001 aaccggccgg gaagagacga gccaccagaa tggccgcgat aaggatcgca agcgacagcg
     9061 gcgccgccac ggtgccaatc agcatccccc gcccaacctg accgagtttg cccgggctct
     9121 tggcaacaac ggaggaaatc gacaggtaga tcagcgacac gaggagtacg aagaccgcca
     9181 gcggcggaac tgagagaaca caaagccagg tcgcgaactc caccaccagg atgtgggcca
     9241 gcgccaccgc gaagctgatc ggtccataac ggccggtcgc cccggtcaac gcaacaccaa
     9301 gaaggcgaag gcgatgccgc cgatcaggac aaccgcggcg gcgccggtga cgcctaagcc
     9361 aataccgcgc cgctgcgagg aactcgagtt gagcaacacc gcaccggccc ccagcgaaac
     9421 aagcgtcgcc agggccgtcg cggtcagcaa cagcgtgcgt tcgcttcgcc cgctttccgt
     9481 cggaaatgcc cacttcccca acagccacat ggcggcaagc aacagcagca aacagaattg
     9541 aatgaccacc ggcgccgacc aggtggccga ccgccacgcg gtggcatcca tgtcacgaat
     9601 acgagctaga aacgacatcg gcacccccct gacgcgtcgc gtcactctcc tcgatcggca
     9661 tgcgacacca ctgtcggcaa ccccgccctg gccggcatcc gtgcgctggc aacctaaccc
     9721 gccggcacca gctcgaacct ggcgcatcgc gccgcgacta ccggcatacc tgtctatcag
     9781 acgttcggtt catgccgagg gccaactcca caccgtcagc gccgccaaac ctcagaagaa
     9841 cttcatataa ttaatcatta agtttatgaa gcacatcggg tagcctgggt gcagcaacat
     9901 cgccaatcag ggatgaaccc gagactctct gcacctacga gaggggtgtg ctccggtgtc
     9961 ttctagcgcc cacggccaac ggctgagcga acctgacgaa atggtgtcga ccagacagcg
    10021 accaaccctg tccttggcca cagccgtcga ttcacccgat tccggccgaa tggcgtccac
    10081 cggcgacgcg gtctccctcg gcgacgcaga ttggcgctcc cggctgcgca ccgcggcact
    10141 ggcccagatc gccgacttcg tctctgaccg cagcgccagc gcgcttggcg ggtcggggtg
    10201 ggaggtcgcc ggcgacatac ttctgcggtt tgtttccgag ggcaaatgcc tgagatcgac
    10261 cttcatgtac ctgggctggt tgtgcggcgc cggtcccaac aatgcggcat tatcggccgc
    10321 ggcaagcctg gagctgctgc acgcctttgc gctcctccaa gacgacgtga tggaccaatc
    10381 cccgcaacga cgaggcagtc cagccgtcca tgtccagctg gcccggtgcc accagcggcg
    10441 cgggctatcc ggtgccgcag cacgtttcgg cgaatcggcg gccgtactac tcggagacat
    10501 ctgcctggtc tgggccgagc agatgctgcg cgaaagcggg gtcgaggacc gccgtctgcg
    10561 gcaggtatgg ccccgctacg acgccatgcg catcgaactc gcggtgggcc agctttgcga
    10621 cctgtccaac gatatccgca acctgccgac actggatgcc gtcttggacg tggcgcggcg
    10681 caagtcgggt aactacacgg tgcgccggcc gctcgagatg ggagccgcga tggccgattg
    10741 cgatgagcgc acgctggaac agctcgcgcg atacggcgac gccgttggag aagcgtttca
    10801 actgcgcgac gacatgctgg gagtgtttgg tacaccggcg atcaccggca aacccagtgg
    10861 cgacgatctc cgcgaacgca aggcaaccag cgtcgtggtc gccgcctacg agatggccga
    10921 tccgccgacg cgtcggcagc ttcacgagct gatgcatcgg gctgagctcg acgacgccgc
    10981 ggttgatcac tgcaaacgac tgatcaccgc gacgggagct gtgcagcgaa tcgaggacat
    11041 gattgaccgc cgtgtcgatc gcgttcgaac actattggcc gacatgacga tcgggcagca
    11101 aacccgcgcc gcgctgggcg acctggcagc agcctgcgtg cagcgcagca cgtgagatca
    11161 cgcgaattag ggagccgcga tgcgaaccat tgaaggcact gccgatcacg tggtggtgat
    11221 cggtgcggga ctagcggggt tggccacggc gctgcacctg gcgggccgcg gccgcagcgt
    11281 cacggtcgtc gaacgcgagg cttggccggg tggacgtgcc ggccgactcg acatcgatgg
    11341 ataccgaatc gataccggcc caactgttct caccatgcca gaccttatcg acgaggtctt
    11401 tgcggccgtg ggtgagacga tctcggatcg gctggagttg cttcccgtcg atccggccta
    11461 caccgccatg ttcgccgacg gaagttcgat cgatgtgcac tgcgacgcgg atcggatggt
    11521 cgcggcgatc gagaacttcg ccggtcccga gcaagctacc ggttatcttc ggctgcgcga
    11581 gtggttgacc cgcctgtacc gcatcgaatt cgccggcttc attggctcga acttcgattc
    11641 gcccctatca ctgctcaccc cgcagctggc gcgactggcg gctgccggcg gatttcgcaa
    11701 ctgggacagc atggtcaagc gccacatcac cgacccgagg ctgcgtcggg tgttcacctt
    11761 ccagtccctc tacgccgggg tggcgccgca agatgcactg gcggcctatg ccgttatcgc
    11821 ctatatggac accatatcgg gggtgttctt tccgcgcggc ggggttcgtg ccctgcctga
    11881 cgcgctggcg gccgccgcgg cctgcgcggg cgtgcagttt cattacggtt cgcaggtaag
    11941 cgaactcgag cgcgacgacg cgcggataac cgctgtccgc accgacaggg gcgagcgcat
    12001 tgcctgcgat gcagtggtgt tgaccaccga gttgcccacc acataccgcc tactgggccg
    12061 aaccccccgc cggcttcgcc ggctgcgggc ggcaccgtcg gcggtcgtcg tgcacgccgg
    12121 ctgccgcagc gcctcgaccg cgagtgagcc ggcggcccat cacacgattc ttttcggaca
    12181 ggcatgggag cagacgttca ccgacatcat tcgcgacggc cggctgatgc gagatccatc
    12241 gttgttggtc acccgaccga ccgcgggcga tcccgccctc gcaccgccgg gccgagatct
    12301 gctctatcta ctcgcgccgg cacccaacct gaccgcgggc cgggtcgatt ggggcagcgc
    12361 cggtggtagc tacgcgcaat ccatgatcga caccgtcgcc tcccggctgc ttccggacct
    12421 tcgcgacagc gtggaactac tcgacgtcgt cactcccctg gactgggccc ggcagggcat
    12481 ggcggcaggt actccgttcg cgctggcgca tacgttcggc caaaccggtc ccttccgccc
    12541 ggcgaacacg gtgcgcggca tcgacaacgc ggtgctggcg ggttcgtcga cggtacctgg
    12601 cgtgggcgtt ccgacgacgt tgatctccgg gcggctggcc gccgaccgca tcacgggaaa
    12661 caccacccga tcaatccgac acctcgacct gaaagcacag ttgtcatgat tcgcagtgaa
    12721 ttggacgccg ccgggatcgg tgatccccgg ttgcgcgagg cctatcagca aagccgccga
    12781 atcaacgccg ccagcgggcg caccttcttt ttggccacca gactgctggc accggatcag
    12841 cgaccacccg tacacgccct gtacgggttc gcccggtacg ccgacgacat tctggactcc
    12901 ttcgatccgc ggctggacac cgacactcgc gcccagcgac tgcagcagct ggcgcagcag
    12961 ttcttttccg gcgccgacca tcctgataac ccggtacttg ccgcggtcag ccacaccgca
    13021 cgccgctacg gcatcggcgc cgatcttttc gaagatttcc tggagtcgat gcgcatggac
    13081 ctcaccatca ccgactaccc cgaccgggat gcgctcaaca cctacatgcg cggttcagcg
    13141 gaagccattg gcctacagtt actcccgatc ttgggcaccg tcgttccagc acgagaggcc
    13201 atgccctacg cggccgccct gggacgcgca tttcagctca ccaacttcat tcgcgacgtc
    13261 gacgaggacc tggcccgcaa ccgcatctat ctgcccgccg acgaactcgc cgcatacggg
    13321 gttgatcggg atgtgctgat gtggtgtcac cacaaccagc gcagcgatgg ccgggtacgc
    13381 gaagctctgg ccgcccaaca cgagatcacc agagagacct accggttcgc cgccgccggg
    13441 atccaactgc tggcgccgcg gtcgcggcct tgtgtcgcga cggctttgac gctgtattcg
    13501 gaaatcctgg accgcatcga aggcgacgat tttgcggtgt tcggccggcg cgccaccgtc
    13561 gggaccgccc gccgtctgcg ggtggccggt gccgggctga tacgagcgtg gcgcgcccga
    13621 accagcgacg ccatccccga tcgctccgag tacggtgccg catgagcgat cgctggcaat
    13681 acctgctggt gctgctcgca tgcctggcga tcaccgcgcc gctggaagtg ttcggcgccg
    13741 gcgtatatcg gcgcccgcga aggctgctgc ggtcggtact accggtggcc gcggcattcc
    13801 tggtctggga cgagttggcc gttgccgcac gggtgtggac ttacgatccg cgctacatca
    13861 gcgggctgaa cgtcccgttt caggtcccga tcgaagaggt cctgttcttt ctggtgatcc
    13921 ccatctgcgc cctgttgacc ctcaacgcgg tcagcaccat cctcgaccgg ctccgccgac
    13981 gatgaccggg ttgggataca ccctgccggc cgtgctggcc gtggccggcg ttggcgccct
    14041 ggagctgttg gtactacgga ccgggttgtt ccggcgtccc gcttactggc tatcgatggt
    14101 gatagtgctg ggctttcagg ttccggtcga cggctggctt accaagctca gcgctcccat
    14161 cgtcagctac aacgagcggc agatcaccgg cctgcggttc ccgttcgaca tcccgattga
    14221 agacttcctg ttcggcttcg cgatggtcac tgccgttctg ctgctgtggg agcgacaacg
    14281 ggaacccggt gagcccgcac cgccgagtca ggcgggctgc cacgagaagc acagcctcga
    14341 ggacaagaca tgttgaccag aatggcccga ctctccctct ccgcgccacg gcgggtcatc
    14401 gcggtggtag tcctggtcat gatcggcacc gccatcttcg gcatcccggc ggcaaatagc
    14461 ctggcggccg ggggttttct ggatccatcg tcggaatccg cgcgtgccgc ggcggtgctc
    14521 gccgacaagt tccatcgagg cgacatggag atggtgctgc tggtgagttc ggatgacggt
    14581 gtccgcgatg gcccggcgcg catcgtcggc accgatatcg cgcgccaact cgcgcaatcg
    14641 cccttcgtgg cgcaggtggc atcgccttgg gacacaccgc aaccgccgcc ggacatgctc
    14701 agcgccgacg ggaaatcggc gctgattctg gtcgcgctca agggcgacga aaacagcgca
    14761 ccccggcatg cgcaggcgct ggcgcagcgg ttggcgcacg accgcggtgg ggtgacggtg
    14821 caggccggtg ggtccgcgat ggtctatgca caggtcaacc agcagaccga aaaggacttg
    14881 ctgcgaatgg agttcatcgc ggtcccggtc agtttcgccg cgctggtgtg ggtgttcggg
    14941 ggtttgctgg ccgcggccct accggtggcc gtgggcggct tcgccattct ggggtccctg
    15001 gcggtgctgc gcggtgtcgc gatggtgacc gatgtgtcga tcttcgcgct aaatgtcacg
    15061 gttgccctgg gcatggccct cgcgatcgac tacaccttgc tgatcatccg ccggtaccgt
    15121 gacgagctcg gcgaggggcg cagccacgag gacgccctgg ttcgcaccat gacaaccgcc
    15181 ggccgcaccg tcctgttctc ggcggtgacg gttgggctct cgctcgtcgc gatggcgctg
    15241 ttcccgatgt acttcctgaa gtccttcgcc tacgccgggg ttgcggtcgt ggcgttttcg
    15301 gccctggccg cgatggtggt cgcaccaacg gtgatcgtgc tgctcggcga ccggctcgac
    15361 gcgctcaacg tctggaaact gggccggcgg ctgcttgggc gtccggaacc gccgccgcgg
    15421 cccgttgcgc agagtttctg gtaccgcacg gccaaactgg tcacccgcca cgcgattccg
    15481 gtgggcctgg ccatcatcgt gttgttgatc gcgctgggaa tcccgttcct caacatcaag
    15541 tggggctatc cggacgaccg cgtgctgccg ccgtccgcgt cggcacgcat ggtcagtgac
    15601 cgaatccgca gcgatttcgg ctcgaactcg gcgagcagag tcaccgtcgt catcaccgac
    15661 accgccgggc tgaccaaacc ggatctcaat cactacgccg cccaattgtc cgaggtatcc
    15721 gatgtgtcgg cggtctcggc gccgacgggc accttcgttg ccggcgagtt gcggggcccg
    15781 ccctccgcac cgaccgcgat ggccgccggc agcgcgtacc tgaccgtgga gagcaccgcg
    15841 ccgctgtaca ccaaggcctc ggcgaaccag ctggatcgtc tgcacgccgt ggcgctgccc
    15901 ggcgacaccg cggtgcaaat gaccggcgtc gcacagatga accgcgactc cgtcaatggg
    15961 attacctcgc ggctacccat ggtgttcggc ttcatcgcga tcgtgacact ggtgctgctg
    16021 ttcctgctca ccggcagtgt gctgctaccg atcaaggcgg tggtgctcaa catgctctcg
    16081 cttacagcgg ctttcggcgc cctggtctgg atctttcagg acggccatct gggcgcgctg
    16141 ggtaccacac caaccggcac gttggtcgcc aatatcccgg tgctgatgtt ctgcatcgcc
    16201 ttcggcttgt cgatggatta cgaagtcttc ctgctgtccc gcatccgcga gttctggctt
    16261 ggatcacctc aacaaagcgc cgacaacgat gagagcatcg ctctgggcct ggcccacacc
    16321 ggccgggtca tcaccgccgc ggcgttgctg atgtcgatct cgtttgccgg cctgatttcc
    16381 gcagaggtgt ctttcatgcg gatgttcggg gtgggtctga ccattgcggt gctggtcgac
    16441 gccacattgg tgcgggtgct gctggtgccc gcgttcatgc atgtgtttgg cggattgaac
    16501 tggtgggcac ccaaaccact ggaacggtgg cacagccgca gcggtgccga ccgatccgcg
    16561 ggccaaaccg gccccagcga cggtgccgtc ggcggcaact ccagcaaatt cgacagcaat
    16621 cgccgcgtcg acgaccacgt gcaccggtcg ccgcgatagg ggcgataagc tagtcgctct
    16681 atctatcgcc cgaaaaggat gcaggcaggt gaccaagcgc gtcgctgtga atcgacagcc
    16741 gagtcgagcc gagctggagc ggctgttatc ggctgatctg cgcgcaatca ccgctcattc
    16801 tgaccgtgtc ggccgctact acgcccgaca caacgatctc agccacggcg acttccaggc
    16861 gttgctgcac atcatggtcg ccgagaccgc ggggacaccc gtgacaccgg cccagctcag
    16921 ccagcgattg gacgtctcgg ccgctgcgat cacctatctt gccgatcgga tgatccatgc
    16981 cgggcacatc cgccgcgaag ccgatccgga cgaccggcgc aaatcacacc ttcgcttcga
    17041 gcaaagcagc ctggagctcg cacacaagtt tttcatgccg ctcggcgacc acatgcgcga
    17101 ggcgatggct gatctgtccg accgcgatct gcgggccgca caccgggtgt tgacggcgat
    17161 gatggacggg atggagacct tcgaaaagga gctctacgag tcgcccgcgc cgacatcggg
    17221 gcgcccccgc aaaacgccgg cgcaggcgga aagcccctaa accgctcggc taccggatgg
    17281 ctgtcacacc gatgtcgcgc agcgacgtga gatcccgcgc accgcaacag tgcaggcaga
    17341 ctcggagttc gtcgaggaac agctgcagcc aaccctgcac cgccgtggcg gattcgatcg
    17401 ccggcgcaag caacgggcgg gcaatcgcga ccacatcggc gcccagggcg atcgctttgg
    17461 ccgcatccat tccggtgcgg atgccaccgg aggcgaccag cgggacagcc ggcaacgctt
    17521 ggcgcacctc gacaatcgcc tcagcggtgg ggatacccca gtcagccaat tccggatagc
    17581 gcagctcgcc gtagcgaacc aactgctcca cccgcgacca tgaggttcct ccggcgccgg
    17641 ccacgtcgat acccgatacc ggcagcccgc cgggcagccg cagcagctgc gcgacggccg
    17701 cggccccgat accgtggcca acctccttga gcagcaccgg atagtccagc aggtcggccg
    17761 cgtcgcgcag ccggcccagc gacccggaga agtcggtatc accaccgtgc tgcatcgctt
    17821 cctgcagtga gttagcgtgc accgcaagtg cattcgcgcc aacccggcgc agcgcggcgg
    17881 ccaccgcggg aaccgcggcc ttggtcaact gagccagacc gatgttgccg atcaacaaca
    17941 cgtcgggtgc cacctcgcgc accgcgaaac tcgacgccgc ccgctgcccg cgggcatcgt
    18001 cgagcatgat ccgctgcgag cccagcatca ttccgatacc gaggcgctgc gcggcggtgg
    18061 ccaaatttcg gttgatcgtc gcggacagct cggcaccgcc ggtcatcgcg ccgatcagga
    18121 ccggggcacg caatggcgcg ccgaaaaact cggccgacaa gtcgatgtcg gcgaggctgg
    18181 tttgggtcag tgcgttgaag ggcaggcggt agcgttcgag cccggtcgtc acgccgacgt
    18241 agttgacctc gtcgttgagg cacacgtcga tgtgccggcg cttacggctg gagatctcgg
    18301 ccgggtcgtt ggtcatcggg cagcaccggc cgtcgcgatc atgatcctcg tcgcggcaag
    18361 caatgcgagt ccttcttggg gttcaacgac gccgtcactg atgtcacaga gcctaccgcg
    18421 cgcgcggttt ggtcaagttg ccgaaatgtc acacaacggg caggaatcga cccgtgcggc
    18481 ggtcatcgcg agctcggcgg cggccaccag aacccgaggc cagatagccg cgtcggccag
    18541 cgcgaagtcc tggcgctggc gcgcgcgagt ccgcacctgg tcgacagcac catcggtgtc
    18601 ccacaacgcc agcgcgcgac cgttgctgtg cgcggcgtgg tagtagacac cgtgtaccgg
    18661 gcggcgtgcc ggctgatctt cgtagatggc ccgtgcccag gcctgagtgc gaacccgtgg
    18721 ataggcgccg gtggccagcg acggcaacgc gccaatgcgc atcgcggcgc cctcggatcg
    18781 cagatccagc accacgatct cggtgcgcgg acgcaacagc ccgacgcgaa accggggaca
    18841 gacggcggcc tcgcccaggt caccaaagac ctcgcccagc gcggtggcca gggtgccggc
    18901 aacgtagagc acagatcttc cctcgggaca gatcgccgga tgagctgccg gcggcgtgtg
    18961 gtggtcgagg cgatgcagcg gcccgaaggc gcgatgggtg atggcgtccg gggtgtgcgc
    19021 ggacaggtga tagacccggc accactgcca gccgcgggcg ctcagcgttt ccggccactt
    19081 ccacgtccag acccgaccac ctgagagcgg acgattcggt tcgccgaggt cggctaccac
    19141 gccgccgcgg tcgacttcgc caccaccgcg atcacatcgt cgacgcgacc ggcggccagg
    19201 gcatcggccg gtgtgatgtc acccagttcc gggttcggcg tggcggccca cttgctcaag
    19261 gcgacgattc cccccggaaa ggcctgtcgc agttcggcga ttcccgacag aaagccgcgt
    19321 tgtgccccgg cgttgagctg ccacatgggt attcgccact ggcgcccgtc cttgagaccg
    19381 atcaggtcgc caccggtgat ccggtcaagc acggcctggc tggagatgtc gagcaactcg
    19441 gcaacctccg ccgtcgacag cgacatggtc agcaattctc ggcgggcgac gaagtcgtcc
    19501 tgcaatgcct gcagcgcagc gctgctcatc tccttggcgg ttggcgcact accccacaac
    19561 gattcgtcca gaccgcccgt gtcccgtgcc gcgacggctt cgacaaagcc cgctttgacc
    19621 gacgcgggcg ccgcgtccaa caccgcgtgc accgcggaac tcagctgtgc ggccgacgcg
    19681 ctggcccgct gacgccgtcg cggcgccgcc ttacgcgtcg gggtgcgggt gaccatacct
    19741 cgaggttata ccaagataac caagcaaaca cggcctcatc gcgcccgatc gggcccggca
    19801 gtcaccgccg gattccgcta tttcttgtcc atcggccccg ggttggcaac cacgggaaat
    19861 tcaccggtat agccgatacg tctgcgcgca atctccagca cgcggtcgcg gaccaggaac
    19921 caaccgccga tcagcatcgg aatgatcagt cccagggtcg ccaccgtcca ggtgccgatt
    19981 gggtaggaga accccatcag aaccagcacc gcgaacagga acaccaaggt gagataaccg
    20041 gtgtagggcg cgccccacat ccgaaacgac ggccggtaca cgatgccctg cttcgaccag
    20101 cggaacagct ggatctggca gcacacgatg gttgcccagg acgcgaggat gcccagcgcc
    20161 gcgatattga ggacgatctc gaaagccatc tcgggcacga cgccgttgag cagcaccccg
    20221 atcaggccga tggcagccgt cagacagatc ccgccgtagg gaactcctcg ttgcgacatc
    20281 cgtgcggtga aactcggggc actgccgttc atcgccatcg accgcaggat gcgcccggtc
    20341 gaatacaaac ccgcgttgag gctggagaac gccgcggtca tcaccaccac gttcatgatc
    20401 gagccggcgc cggtgacccc gatcttgtcg aagaaggtga caaacgggct ctcaccggcc
    20461 ttgtagtcgg tgtagggcag cagcaggccg agcaagaaca gcgatccaac gtagaacagg
    20521 gcaatacgcg cgatcaccga gttgatggca cgcggcatca ccttctccgg ctccgccgtc
    20581 tcccccgctg ccgtgccgac cagctcgacc gccgcatagg cgaagaccac gcccgaggtg
    20641 acgacgacca gcggcagcag gccgtacggg aagagtccgc cgccgtgggc gagcaggccg
    20701 agaccggtgg aatgaccatc gacggggtaa cggccggcca ggaatatggt gcccacgacc
    20761 aggaaggtca gcagcgacac caccttgatc agggccgccc agaactcgat ctcaccgaac
    20821 agggtcaccg agatcaggtt catgctcaac gcgataccca gcgcgaacaa cgccagcgcc
    20881 cactgcggga tgccctcgaa cacccgccag aaatggaagt aggtggcgat cgctgtcgag
    20941 tcgacaatcg aggtcatcgc ccagttcagg aaatacatcc agccggcgac ataggccgcc
    21001 ttttcgccga agaattcgcg cgcataggag acaaacgagc ccgacgacgg ccggtgcagc
    21061 acgagttcac ccaacgcccg caagatcagg aaggcgaaca ctccacagac cgcgtagacc
    21121 agaaacagtg ccggaccggc gctggccagc cgtccaccgg cgccaaggaa caggccggtg
    21181 ccaatcgcac cgccgatcgc gatcatctgt agctggcgcg gcttaaggct cttgtgatag
    21241 ccggcatctt cgctcgcgag agcgatgtca tcgggatggg tcgggctcga cggggttctc
    21301 aacgctcaga tgcctctttc ccagttcggt cgctggctgt ggggatcagc cgccgggggc
    21361 aggttccgag cccgcgggat cgtccgggcc cggagtatgt ggtggtgtcg gaatatcacg
    21421 aaacgtaaag atgaagccga acgccgccac cgcggcggcg atcgcatagc cgatgatcga
    21481 ataccaacct gcgtgcaggt atgcggtaac cgcgacaagt gccatggcac caaagaccat
    21541 cgacattccg ataagcggcg tcttggcctt gaaatcaaca aagcgcatgg ataaaaacct
    21601 cgtcgggtgg cgaacgaatg tggactaagt aaacacggtg tggacgatca tgtcctgttg
    21661 ggcgaccgac ccgccaaccc accccttgtg ctataagacc aatccgctgc gcctttgccg
    21721 cgacaatggc caccgatcag ttgcgtcgtg tcccggcccg ccgcggtcgc ggggtggtca
    21781 cggcgcgagc ggcgagatca tccggctgat cgtcgcgacc cgacggtcga gccggtcggc
    21841 cggaatatcg atgagttgat aaccgaattc gcggtagctg tcttcgtgga ttcgttcgaa
    21901 cctcaacgcc tccgccatgt cgattcggcg ggtcgtggtg ggttggcaga agcccaagtt
    21961 ccggacgaaa aagacctgcc gctgataggt gtgctcggcg gcaatccggt caagctcggc
    22021 cgtcagcgcc gcgcaaacgg gcagcccgag atagacggcg agcgcgtggg tgcacaccgg
    22081 cgagcggtca aagaagcaaa cgccggggcc cgtcgggtcg gccgcaactt ggcgccggcg
    22141 ctgtgtctcg acaacctcgt cgataaacga cgctttggtc gcacccgtcc agggtgcgtc
    22201 ttcgccgcgc gcctgccgac cgaggatgac atcggtggcg gcctccgcca cgacggcgtg
    22261 tccgagctgt gcgagccgcc gcaagatcga cgtcttaccc gctcccggcg tgccggtgag
    22321 aatgtatcgg cgggtcaatt tcgttggttt cctcggtgtc ggtggacggt aatcgccgcg
    22381 ggcgcggctc gacgcgaccc gatggggtgg tggcgtgggc gggagacccc gcggccggag
    22441 ccggaatcgt tcccgattca accccttgag gcaacatctg caagatgtga cgattgcctc
    22501 aatggatgcc tcagtggatg cctcgatgca ggaccttcaa ggcaaggtgg ccgtggtgac
    22561 cggcggggcc ggaggcatag gccgagccct ggggaagcgc ttcggcatgg aaggcatgaa
    22621 ggtggtgctc gccgacgtcc tcgccgaacc gctggaccgg gcgacccgcg cactcacgga
    22681 cgagggcatc gaggcggtcg gcgtggttac cgacgttacc gactattcct cggtcgaggc
    22741 gttggccaag gagacgttgc accgattcgg cgcggtgcac gtggtgtgca acaacgccgg
    22801 caccggcggg gtctccgagg gctacatgtg ggaacacgac ctagccgact ggcactgggg
    22861 gatagatgtc aacgtcgtgg gcgtcatcca cggcatcaaa gccttcgtgc ccatcctgct
    22921 cgagcgcggc gagggacacg tggtgaacac ctgctcgggc aacggcgggt tcgcgccgat
    22981 cgcccggggg gccatgggcg ggccggccat ggcggtctat ccgatgacca aggccgccgt
    23041 gctctgcctg accgagagcc tctacaccca cctggagatg accgggacgc gggtgcgggc
    23101 gcatgccctt ttccccggcg gtttcctcaa caccggcatc tgggagtcat ggcggcaccg
    23161 gccacagcgc tacgccgcga cccagacgcg ccgcaccccc gagcacaccc tggccgacgt
    23221 cgtgggtcgc ttcgaggccg ccggcgcccg cgtcgagttc accccgctcg ccgcggtcgc
    23281 cgaccaagtg gtggagggaa tacgagccga ccggttctgg atgatgggcc cgcccacacc
    23341 ggccgatgag gtggtcaccc gcaaggcggc atcgatcgtg gcccgcgccg accccgacta
    23401 cctggtggat gtgctcggcc gcagcgccgc caaggagccg gaaaccgaag gaggaaagcg
    23461 ttgattacca acgcagttcg ctatggtccc cgcccacccg aggcgcaagt cgaccatgag
    23521 atcgatgcca ccaaggcgcc catcgccacc gaggcggtga ccgtcaccta cctcaccgat
    23581 ccgcagatcg tcgcggccgt gctgcccaaa ccgctgcagc cggccgacga accgctggtg
    23641 cgggtccagc tgcagcgggt ccagatagcg ggccgcccgc cattcgggtc ggcggtgttt
    23701 gcggtgaccg cccggcacgg cgacctgcag ggggactacc cccttttcat gccccagtcg
    23761 accgaacagt cggtcaccgg tgggcgcgaa acattcggtg aaccaaagaa attggcccac
    23821 atcgaggtcg accatgacgg tagccgcgtc agcgccaccg ttgaccggat gggctatcgg
    23881 ctgatcaccg tcagcggtca ggtgagcggc ggcgcgccgt tgccgcccga ccaggtgaac
    23941 accgagttct acttcaagtt cctgcgctcc cccgacggca acggcatcac cgacccgcac
    24001 ttggtctacg gcgaatatca ccgccactac gagctgctgg agaacatcga cggcagcctc
    24061 gagctcggcg agtctccgct ggaccccgtg gccgacatcg tgattcgcca gatcaggtcg
    24121 atcacctggt gccgccggcg caccatccag gtgggtcgga tcgccacccg ggtaccccag
    24181 gagtggctgc tgccctatgt gcaccagcgc tatgacgaac cccatgacgc cccagccccg
    24241 gccacgcccc ccagccctga gccggcccgg gcatagccat ggaccgatac acggttattt
    24301 cggctgactg ccacgccggg gcggacctgc tcgactaccg cgagtatctc gaggcg
//
