LOCUS       NC_010612              22677 bp    DNA     circular CON 17-DEC-2024
DEFINITION  Mycobacterium marinum M, complete sequence.
ACCESSION   NC_010612
VERSION     NC_010612.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium marinum M
  ORGANISM  Mycobacterium marinum M
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
REFERENCE   1  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Davies,J.K.,
            Johnson,P.D., Abdellah,Z., Arrowsmith,C., Chillingworth,T.,
            Churcher,C., Clarke,K., Cronin,A., Davis,P., Goodhead,I.,
            Holroyd,N., Jagels,K., Lord,A., Moule,S., Mungall,K.,
            Norbertczak,H., Quail,M.A., Rabbinowitsch,E., Walker,D., White,B.,
            Whitehead,S., Small,P.L., Brosch,R., Ramakrishnan,L.,
            Fischbach,M.A., Parkhill,J. and Cole,S.T.
  TITLE     Insights from the complete genome sequence of Mycobacterium marinum
            on the evolution of Mycobacterium tuberculosis
  JOURNAL   Genome Res 18 (5), 729-741 (2008)
   PUBMED   18403782
REFERENCE   2  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Pidot,S.J.,
            Davies,J.K., Small,P.L.C., Johnson,P.D.R., Brosch,R., Cole,S.T.,
            Ramakrishnan,L. and Parkhill,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2007) Pathogen Sequencing Unit, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000018345.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,598
            CDSs (total)                      :: 5,546
            Genes (coding)                    :: 5,407
            CDSs (with protein)               :: 5,407
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 53 of 139
            Pseudo Genes (incomplete)         :: 113 of 139
            Pseudo Genes (internal stop)      :: 14 of 139
            Pseudo Genes (multiple problems)  :: 34 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1236233
            Orig. end                         :: 1258910
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000854.1.
            DNA and bacteria are available from Dr Lalita Ramakrishnan,
            lalitar@u.washington.edu.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22677
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="8"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22677
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22677
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12677](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12677
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    74..89
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            374..748
                     /gene="rpsL"
                     /locus_tag="MMAR_RS04985"
                     /old_locus_tag="MMAR_1011"
     CDS             374..748
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007469952.1"
                     /locus_tag="MMAR_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1011"
                     /product="30S ribosomal protein S12"
                     /protein_id="WP_003879423.1"
                     /transl_table=11
                     /translation="MPTIQQLVRKGRRDKIGKVKTAALKGSPQRRGVCTRVYTTTPKKP
                     NSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDT
                     QGVKNRKQARSRYGAKKEKS"
     gene            748..1218
                     /gene="rpsG"
                     /locus_tag="MMAR_RS04990"
                     /old_locus_tag="MMAR_1012"
     CDS             748..1218
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012084986.1"
                     /locus_tag="MMAR_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1012"
                     /product="30S ribosomal protein S7"
                     /protein_id="WP_012392921.1"
                     /transl_table=11
                     /translation="MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLQGKKSLAERIVYG
                     ALEQARDKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWL
                     VGYSRQRREKTMIERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW"
     gene            1299..3404
                     /gene="fusA"
                     /locus_tag="MMAR_RS04995"
                     /old_locus_tag="MMAR_1013"
     CDS             1299..3404
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fusA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_177746.1"
                     /locus_tag="MMAR_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1013"
                     /product="elongation factor G"
                     /protein_id="WP_012392922.1"
                     /transl_table=11
                     /translation="MAQKDVLTDLTKVRNIGIMAHIDAGKTTTTERILYYTGISYKIGE
                     VHDGAATMDWMEQEQERGITITSAATTCFWNDNQINIIDTPGHVDFTVEVERSLRVLDG
                     AVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKMDKIGADFYFSVRTMEERLGANVI
                     PIQLPVGSEGDFEGVVDLVEMKAKVWSADAKLGEKYDVVDIPADLQEKADEYRTKLLEA
                     VAETDEALLEKYLGGEELTEAEIKGAIRKLTITSEAYPVLCGSAFKNKGVQPMLDAVID
                     YLPSPLDVPAAIGHVPGKEDEEVVRKPSTDEPFSALAFKVATHPFFGKLTYVRVYSGKV
                     DSGSQVINSTKGKKERLGKLFQMHSNKENPVETASAGHIYAVIGLKDTTTGDTLSDPNN
                     QIVLESMTFPDPVIEVAIEPKTKSDQEKLSLSIQKLAEEDPTFKVHLDQETGQTVIGGM
                     GELHLDILVDRMRREFKVEANVGKPQVAYKETIKRLVEKVEFTHKKQTGGSGQFAKVLI
                     SIEPFTGEDGATYEFESKVTGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNLKVTLLD
                     GAFHEVDSSEMAFKIAGSQVLKKAAAAAHPVILEPIMAVEVTTPEDYMGDVIGDLNSRR
                     GQIQAMEERSGARVVKAHVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEI
                     IAKATGE"
     misc_feature    3553..3562
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            3591..4781
                     /gene="tuf"
                     /locus_tag="MMAR_RS05000"
                     /old_locus_tag="MMAR_1014"
     CDS             3591..4781
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tuf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005055596.1"
                     /locus_tag="MMAR_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1014"
                     /product="elongation factor Tu"
                     /protein_id="WP_011739036.1"
                     /transl_table=11
                     /translation="MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNE
                     SRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGA
                     ILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLELVEMEVRELLAAQ
                     EFDEDAPVVRVSALKALEGDPKWVESVEQLMDAVDESIPDPVRETDRPFLMPVEDVFTI
                     TGRGTVVTGRVERGIINVNEEVEIVGIRPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLL
                     RGIKREDVERGQVVVKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDV
                     TGVVTLPEGTEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK"
     gene            5031..5840
                     /locus_tag="MMAR_RS05005"
                     /old_locus_tag="MMAR_1015"
     CDS             5031..5840
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215200.1"
                     /locus_tag="MMAR_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1015"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_012392923.1"
                     /transl_table=11
                     /translation="MLARYLKMQLLVLLCGGLVGPIFLIVYFALGVGSLLSWMLYVGLL
                     ITVADVLIALALTNFGAKSAAKSAELEQSGVLALAQITGLTETGTRINDRPLVKVHLHI
                     SGPGIAAFDSEDRVIASVTRLGNLTARKLVVLVNPTTQEYLIDWERSALVNGLVPAQFT
                     VAEDNRTYDLSGQAGPLMEILQILKANGIPLNRMVDIRSNPVLRQQIQAVVRRAAQQQM
                     PAGAAQPSAAPQASIAERLQELESLHASGALNAQEYASRRAQIISEI"
     gene            5974..6801
                     /locus_tag="MMAR_RS05010"
                     /old_locus_tag="MMAR_1016"
     CDS             5974..6801
                     /NRPS_PKS="Domain: PKS_KR (11-183). E-value: 3.4e-15.
                     Score: 48.3. Matches aSDomain:
                     nrpspksdomains_MMAR_RS05010_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215201.1"
                     /locus_tag="MMAR_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1016"
                     /product="mycofactocin-coupled SDR family oxidoreductase"
                     /protein_id="WP_012392924.1"
                     /sec_met_domain="adh_short (E-value: 8.3e-32, bitscore:
                     108.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAQTGSLDGRVAFVTGAARAQGRSHAVRLAREGADIIAMDICGP
                     VSETITYAPATAADLSETIRAVESEGRKVLARQADVRDSAALQQLVADGVEEFGRLDVV
                     VANAGVLGWGRLWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIEAGNGGSIIVVSSSAG
                     LKATPGNGHYAASKHGLVALTNTLAIELGEYDIRVNSIHPYSVETPMIEPDVMMQVFGE
                     HPRFLHSFPPMPLQYKGLMTSEEVSDVVVWLAGDGSGTLSGAQIPVDKGALKY"
     aSDomain        6007..6522
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS05010_PKS_KR.1"
                     /evalue="3.40E-15"
                     /label="MMAR_RS05010_PKS_KR.1"
                     /locus_tag="MMAR_RS05010"
                     /protein_end="183"
                     /protein_start="11"
                     /score="48.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAFVTGAARAQGRSHAVRLAREGADIIAMDICGPVSETITYAPAT
                     AADLSETIRAVESEGRKVLARQADVRDSAALQQLVADGVEEFGRLDVVVANAGVLGWGR
                     LWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIEAGNGGSIIVVSSSAGLKATPGNGHYA
                     ASKHGLVAL"
     misc_feature    6691..6693
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6811..8049
                     /locus_tag="MMAR_RS05015"
                     /old_locus_tag="MMAR_1017"
     CDS             6811..8049
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020788576.1"
                     /locus_tag="MMAR_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1017"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_012392925.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.7e-59, bitscore:
                     198.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEHHVTSSEGVTQDPGATAANGIVIIGGGLAAARTAEQLRRAGY
                     EGQLTIVSDEVHLPYDRPPLSKEVLRSEVDDVSLKPREWYDEKDIALRLGSAATGLDTA
                     AQTVTLADGTVLGYDELVIATGLVPRRIPAFPELEGIRVLRSFDECMALRSHASAAKRA
                     VVIGAGFIGCEVAASLRGLGVEVVLVEPQPTPLAAVLGEQIGELVARLHRSEGVDVRTG
                     VGVAEVRGDGHVDTVVLADGTQLDADLVVVGIGSHPATGWLDGSGIAVDNGVVCDAAGR
                     TSAPNVWALGDVASWRDQMGHQVRVEHWSNVADQARVVVPAMLGREVSSNVVVPYFWSD
                     QYDVKIQCLGEPHSTDVVHLVEDDGRKFLAYYERDGVLVGVVGGGVPGKVMKVRAKIAA
                     AVPISEMLDESQG"
     gene            complement(8148..9209)
                     /locus_tag="MMAR_RS05020"
                     /old_locus_tag="MMAR_1018"
     CDS             complement(8148..9209)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011739040.1"
                     /locus_tag="MMAR_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1018"
                     /product="DUF2332 domain-containing protein"
                     /protein_id="WP_012392926.1"
                     /transl_table=11
                     /translation="MQEAKSGGIEHLLHTLRSQGRFCARSGSPMYGELFELVAADVEAG
                     GVFAPILAGHEDDPSRYATPLRLLGGLHRMVLDGRAPTLRRWYPSTDGSWDAKSAWPEI
                     ELVAANHTEALRGALDQPPQTNEVGRSAALIGGLLHIRHEFNFPVRLFEIGASAGLNLR
                     ADRYHYRYAGMTWGPIDSPVIIEDAWRGELPPALALQIVERHGYDIAPIDICGTDGEMT
                     VLSYVWPDQHARMKRLRGAIAVARDVPAQLERKTAADGVAGLTLQDETLTVLWHSITWQ
                     YLAAQERAAIRDRVAELGAQAGPRSPFAHLTLEPARDEGGRLKFLVRLASWPSGEARVL
                     GQCHPHGPPVNWQ"
     gene            complement(9209..9802)
                     /gene="mftR"
                     /locus_tag="MMAR_RS05025"
                     /old_locus_tag="MMAR_1019"
     CDS             complement(9209..9802)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0036042 - long-chain fatty acyl-CoA
                     binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="mftR"
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020731934.1"
                     /locus_tag="MMAR_RS05025"
                     /note="MftR, the mycofactocin system transcriptional
                     regulator, is an uncharacterized TetR family DNA-binding
                     transcription factor. Its role is inferred by context. It
                     occurs as part of the biosynthesis locus for mycofactocin,
                     a partially characterized electron carrier derived from the
                     terminal Val-Tyr dipeptide of the precursor peptide MftA,
                     through a radical SAM enzyme-mediated process; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MMAR_1019"
                     /product="mycofactocin system transcriptional regulator"
                     /protein_id="WP_011739041.1"
                     /transl_table=11
                     /translation="MAHESRAGRRPSTTKRHIADVAIDLFAARTFAEVSVDDVAQAAGI
                     ARRTLFRYYASKNAIPWGDFDTHLAQLQDLLERIDGHVRLGKALREALLAFNTYDESET
                     IRHRQRMRIILQTAELQAYSMTMYAGWRAVIAGFVARRLSVKPTDLVPQTVAWTMLGVA
                     LSAYEHWLSDESVSLPEALGNAFDVVGAGLEKLD"
     misc_feature    complement(9269..9271)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9773..9787
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.44"
                     /tool="antismash"
     misc_feature    9882..9899
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.65"
                     /tool="antismash"
     gene            9924..10016
                     /gene="mftA"
                     /locus_tag="MMAR_RS28085"
     CDS             9924..10016
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_007409348.2"
                     /locus_tag="MMAR_RS28085"
                     /note="Mycofactocin is a small molecule electron carrier
                     derived from the final two amino acids, Val-Tyr, of MftA,
                     the mycofactocin precursor. It plays a role in redox
                     homeostasis and the metabolism of alcohols and aldehydes in
                     Actinobacteria, including Mycobacterium tuberculosis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="mycofactocin precursor MftA"
                     /protein_id="WP_071498352.1"
                     /transl_table=11
                     /translation="MDRETEAETAELVTESLVEEVSIDGMCGVY"
     gene            10001..10330
                     /gene="mftB"
                     /locus_tag="MMAR_RS05035"
                     /old_locus_tag="MMAR_1020"
     CDS             10001..10330
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: Mycofactocin_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215206.1"
                     /locus_tag="MMAR_RS05035"
                     /note="MftB, a small protein, is a peptide chaperone that
                     assists the radical SAM enzyme MftC in performing two
                     modifications to the C-terminal Val-Tyr dipeptide of the
                     mycofactocin precursor peptide, MftA. MftB's role is
                     analogous to the role of PqqD in the biosynthesis of PQQ, a
                     cofactor that derives entirely from a Tyr and a Glu in the
                     precursor PqqA.; MftB, a small protein, is a peptide
                     chaperone that assists the radical SAM enzyme MftC in
                     performing two modifications to the C-terminal Val-Tyr
                     dipeptide of the mycofactocin precursor peptide, MftA.
                     MftB's role is analogous to the role of PqqD in the
                     biosynthesis of PQQ, a cofactor that derives entirely from
                     a Tyr and a Glu in the precursor PqqA; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MMAR_1020"
                     /product="mycofactocin biosynthesis chaperone MftB"
                     /protein_id="WP_020727427.1"
                     /sec_met_domain="Mycofactocin_RRE (E-value: 4.9e-30,
                     bitscore: 102.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLLTVPAPAQAAAGAGAFDPDRGWRLHPQVAVRPEPFGALLYH
                     FGTRKLSFLKNRTILAVVRSLADHPDVRSACRAAGVDDSEHAPYLHALSVLAGSHMLVP
                     QEADQ"
     aSDomain        10067..10306
                     /aSDomain="Mycofactocin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a mycofactocin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MMAR_RS05035_Mycofactocin_RRE.1"
                     /evalue="2.50E-32"
                     /identifier="RREFam016.1"
                     /label="MMAR_RS05035"
                     /locus_tag="MMAR_RS05035"
                     /protein_end="102"
                     /protein_start="22"
                     /score="102.0"
                     /tool="antismash"
                     /translation="DRGWRLHPQVAVRPEPFGALLYHFGTRKLSFLKNRTILAVVRSLA
                     DHPDVRSACRAAGVDDSEHAPYLHALSVLAGSHML"
     gene            10327..11502
                     /gene="mftC"
                     /locus_tag="MMAR_RS05040"
                     /old_locus_tag="MMAR_1021"
     CDS             10327..11502
                     /EC_number="1.3.98.7"
                     /EC_number="4.1.99.26"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215207.1"
                     /locus_tag="MMAR_RS05040"
                     /note="MftC is a radical SAM/SPASM enzyme that catalyzes
                     the first two steps in biosynthesis of the electron carrier
                     mycofactocin from the terminal Val-Tyr dipeptide of the
                     precursor peptide MftA.; MftC is a radical SAM/SPASM enzyme
                     that catalyzes the first two steps in biosynthesis of the
                     electron carrier mycofactocin from the terminal Val-Tyr
                     dipeptide of the precursor peptide MftA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MMAR_1021"
                     /product="mycofactocin radical SAM maturase"
                     /protein_id="WP_012392928.1"
                     /sec_met_domain="PTHR43273 (E-value: 2.9e-37, bitscore:
                     126.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.2e-23, bitscore: 79.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-05, bitscore: 23.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.8e-09, bitscore: 34.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-13, bitscore:
                     48.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2e-05, bitscore: 23.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVPRLIEQFEHGLDAPICLTWELTYACNLACVHCLSSSGKRD
                     PGELSTRQCQDIIDELERMQVFYVNIGGGEPTVRPDFWELVDYATAHHVGVKFSTNGVR
                     INPEVAARLAASDYVDVQISLDGATAEVNDAVRGAGSFAMAVRALENLAAAGFADAKIS
                     VVVTRHNVGQLDDFAALADRYGATLRITRLRPSGRGADVWEELHPTAAQQVALYDWLVA
                     KGERVLTGDSFFHLAPLGSSGALAGLNMCGAGRVVCLIDPVGDVYACPFAIHDRFLAGN
                     VLTDGGFDQVWKNAPLFRQLREPQSAGACGSCGHYDSCRGGCMAAKFFTGLPLDGPDPE
                     CVQGYGAPALAQERHAPRPRVDHSRGSRVSAPVPLTLTTRPPARLCNESPV"
     gene            11505..12677
                     /gene="mftD"
                     /locus_tag="MMAR_RS05045"
                     /old_locus_tag="MMAR_1022"
     CDS             11505..12677
                     /EC_number="1.4.3.26"
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR03966"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354673.1"
                     /locus_tag="MMAR_RS05045"
                     /note="MftD, an enzyme found in the mycofactocin
                     biosynthesis locus, performs an oxidative deamination of
                     3-amino-5-[(p-hydroxyphenyl)methyl]-4,
                     4-dimethyl-2-pyrrolidinone (AHDP). The resulting compound,
                     now called pre-mycofactocin (PMFT), is a biologically
                     active redox cofactor that can oxidize the non-exchangeable
                     NADH of TIGR03971 family SDR-type oxidoreductases.; MftD,
                     an enzyme found in the mycofactocin biosynthesis locus,
                     performs an oxidative deamination of
                     3-amino-5-[(p-hydroxyphenyl)methyl]-4,
                     4-dimethyl-2-pyrrolidinone (AHDP). The resulting compound,
                     now called pre-mycofactocin (PMFT), is a biologically
                     active redox cofactor that can oxidize the non-exchangeable
                     NADH of TIGR03971 family SDR-type oxidoreductases.; MftD,
                     an enzyme found in the mycofactocin biosynthesis locus,
                     performs an oxidative deamination of
                     3-amino-5-[(p-hydroxyphenyl)methyl]-4,
                     4-dimethyl-2-pyrrolidinone (AHDP). The resulting compound,
                     now called pre-mycofactocin (PMFT), is a biologically
                     active redox cofactor that can oxidize the non-exchangeable
                     NADH of TIGR03971 family SDR-type oxidoreductases.; MftD,
                     an enzyme found in the mycofactocin biosynthesis locus,
                     performs an oxidative deamination of
                     3-amino-5-[(p-hydroxyphenyl)methyl]-4,
                     4-dimethyl-2-pyrrolidinone (AHDP). The resulting compound,
                     now called pre-mycofactocin (PMFT), is a biologically
                     active redox cofactor that can oxidize the non-exchangeable
                     NADH of TIGR03971 family SDR-type oxidoreductases; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="MMAR_1022"
                     /product="pre-mycofactocin synthase MftD"
                     /protein_id="WP_012392929.1"
                     /sec_met_domain="TIGR03966 (E-value: 4e-217, bitscore:
                     718.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEWFETVAIAQQRAKRRLPKSVYSSLISASEKGITVADNVAAF
                     SELGFAPHVIGAAEKRDMSTTVMGQDISMPVLISPTGVQAVHPDGEVAVARAAAARGTA
                     MGLSSFASKTIEDVIAANPKIFFQIYWLGGRDAIAERVERARQAGAVGLIVTTDWTFSH
                     GRDWGSPKIPEQMNLRTILRLSPEAIVRPRWLWKFGKTLRPPDLRVPNQGRRGEPGPAF
                     FAAYGEWMGTPPPTWDDIAWLRELWGGPFMLKGVMRVDDAKRAVDAGVSAISVSNHGGN
                     NLDGTPASIRALPAVAAAVGDQVEVLLDGGIRRGSDVVKAVALGARAVLVGRAYLWGLA
                     ANGQAGVENVLDILRGGIDSALMGLGHSSIHDLRSDDILIPADFVRRLGG"
     gene            12832..13584
                     /gene="mftE"
                     /locus_tag="MMAR_RS05050"
                     /old_locus_tag="MMAR_1023"
     CDS             12832..13584
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215209.1"
                     /locus_tag="MMAR_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1023"
                     /product="mycofactocin biosynthesis peptidyl-dipeptidase
                     MftE"
                     /protein_id="WP_012392930.1"
                     /transl_table=11
                     /translation="MNSSYHRRVPVLGELGTSTSSQLPSTSPSILIPLGSTEQHGPHLP
                     LDTDTRIATAVGRAVATRMHGRLTQCQPGWLLAPPIAYGASGEHQSFAGTISIGTEALR
                     VLLLEYGRSAACWADRLVFVNGHGGNVEALRGAVRQLRAEGRDAGWSACGSAGGDAHAG
                     HTETSVLLHISPEVVLTDRLSAGNAAPLAELLPSLRRGGVAAVSPIGVLGDPTTATAVE
                     GRRIFAEMVDDCVSRIARWTPGPDGMLT"
     gene            13581..14993
                     /gene="mftF"
                     /locus_tag="MMAR_RS05055"
                     /old_locus_tag="MMAR_1024"
     CDS             13581..14993
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0140604 - mycofactocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mftF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020788571.1"
                     /locus_tag="MMAR_RS05055"
                     /note="Members of this protein family, MftF, are
                     glycosyltransferases, members of PF00535 (glycosyl
                     transferase family 2). The encoding gene is found as part
                     of the mycofactocin cassette, in Mycobacterium
                     tuberculosis, many other Actinobacteria, and occasional
                     members of other lineages. Mycofactocin itself, a putative
                     redox carrier, is a heavily modified derivative of the
                     C-terminal Val-Tyr dipeptide of the mycofactocin precursor
                     MftA (TIGR03969).; Members of this protein family, MftF,
                     are glycosyltransferases, members of PF00535 (glycosyl
                     transferase family 2). The encoding gene is found as part
                     of the mycofactocin cassette, in Mycobacterium
                     tuberculosis, many other Actinobacteria, and occasional
                     members of other lineages. Mycofactocin itself, a putative
                     redox carrier, is a heavily modified derivative of the
                     C-terminal Val-Tyr dipeptide of the mycofactocin precursor
                     MftA (TIGR03969); Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1024"
                     /product="mycofactocin biosynthesis glycosyltransferase
                     MftF"
                     /protein_id="WP_012392931.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-24,
                     bitscore: 85.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPRLPDGFAVQVDRRVRVLGGGSALLGGSPTRLLRLAPAAQDM
                     LCDGRLKVRDDISAELARTLLDATVAHPRPASGPSHRDVTVVIPVRDNASGVRRLVASL
                     RGLRVIVVDDGSSSPVELEDFAGAHCDVEVLHHRRSKGPAAARNTGLAACTTEFVAFLD
                     SDVAPRRGWLEALLGHFCDPTVALVAPRIVGLAPSENLVARYEAVRSSLDLGQREAPIL
                     PHSPVSYVPSAAIICRCSAIRQVGGFDETMHSGEDVDLCWRLIESGARLRYEPIALVGH
                     EHRTQLRAWIARKAFYGGSAAPLSVRHPDKTAPLVISGWALTAWVLMSLGTRATQLASL
                     IIAVLTGRRIATALRSAQTSSWDVVVVAARGLWSAALQLASAICRHYWPVTLIAVIVSR
                     HCRRVVLVAAVIDGVVDWLRRREDPDGDSEPIGLLTYLLLKRIDDLAYGLGLWYGVMRE
                     RNAGALKPQIRR"
     misc_feature    14694..14696
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15002..16438
                     /gene="mftG"
                     /locus_tag="MMAR_RS05060"
                     /old_locus_tag="MMAR_1025"
     CDS             15002..16438
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene="mftG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354676.1"
                     /locus_tag="MMAR_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1025"
                     /product="mycofactocin system GMC family oxidoreductase
                     MftG"
                     /protein_id="WP_012392932.1"
                     /transl_table=11
                     /translation="MTAALRHSDVLIVGAGSAGSVLAARLSADPSCAVTLVEAGPGLAD
                     PRLLAQTANGLQLPISADSPLVQRYQSQLTDHPVRRIPILRGATLGGSGAVNGGYFCRG
                     LARDFDGAAIPGWSWSQVLPHFRAIETDLDFDTPVHGRTGPIPVRRTRDQTGVTQRFVT
                     AAQRAGFGWIADLNDVGPDIAAGVGAVPLNIVDGVRTGSGAAYLLPALGRPNLTLLEET
                     RAQQVRFSAATAVGVDAVGPRGPMTLWADRIVLCAGAIGSAHLLMLSGIGDHAMLRSAG
                     VPVVQALPVGMNCSDHPEWALPTTWTVAAGRPVLEAVLNTADGIEIRPYTTGFAAMAGA
                     AAKGHRDWPHLGVALMRPRSRARVTLASPDPSVPPRIGHHYDSEPADVAALQRGTELAR
                     ELAGSAVAGEPGWSTSQHLCGSAPMGVDADPTAVVDPECRVRGIENLWVVDGSILPLIP
                     SRGPHATIVMLGHRAAEFIG"
     misc_feature    16202..16204
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16428..17063)
                     /locus_tag="MMAR_RS05065"
                     /old_locus_tag="MMAR_1026"
     CDS             complement(16428..17063)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392933.1"
                     /locus_tag="MMAR_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1026"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_012392933.1"
                     /transl_table=11
                     /translation="MALDHERLLRAAAEFLGRRPNATQDEIAAAIGVSRATLHRYFAGR
                     AALIDALEQLAFGQMREALKSARWQEGSATEALRRLVAACESVSGYLTLLYAYSQDSDT
                     NELKQGWLEIDSEIKELFLRGQRQGEFRPDLAAGWLTEAFYSLVSGAGWSINTGRAAPR
                     DFAPMITELLLHGVSHSGQPNTNNHHAPERRRLGSEPTRPMINSRVSR"
     misc_feature    complement(17105..17121)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.91"
                     /tool="antismash"
     misc_feature    17105..17121
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.81"
                     /tool="antismash"
     gene            complement(17198..19177)
                     /locus_tag="MMAR_RS05070"
                     /old_locus_tag="MMAR_1027"
     CDS             complement(17198..19177)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1142: PPE family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354678.1"
                     /locus_tag="MMAR_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_1027"
                     /product="PPE family protein"
                     /protein_id="WP_041325133.1"
                     /transl_table=11
                     /translation="MLASFSVLPPEINSARLFGGAGSAPTLAAATAWDGLSAELSGAAG
                     SFGSVTSELAAGVWQGPASAAMTVAAGRYVGWLRTSALHAAGAAAAARAAAAEFEAALA
                     ATVHPVAVAANRAQLASLVMTNLFGQNAPAIAAAESSYEQMWAQDVSAMAGYYGGAAAV
                     AAQLAPWSQQLGTIVGAVGGSAGAGLSRASGLSATAANTSSIGTNVAAAQTIAEVMGGS
                     GIPMPSRRYVQLANSLYIGRSVGGAVAQALFTPEGLYPVTGVKNLTFDTSVARGVVILE
                     SAIREQITAGNNVTVFGYSQSATISSLTMTKLAASINPPTPDQLSFTLVGDPNNPNGGV
                     ATRFPGLSLPSLGITASGATPDNLYPTRIYTLEYDGVADFPRYPLNLVSTLNALAGAYY
                     VHTDYLFLTPAQIDAAVHLTNTVGPTMTDYYVIRTEDLPLLEPLRALPVLGDPLADLVQ
                     PNLKVIVNLGYGDPAYGYSTSPPNVATPFGLWPEVSPLTIADALAAGTQQGIHDFGYHI
                     SHLDLPQITNGSSSPVGNPQAAPTTGPAAPMVSINTIIDDLQAANSQVANTITEVGAAS
                     YAALLPTADIANAAITSVPSYNINLFLDGIQQVANGDPMGFVNAVGYPLAADVALITVA
                     GLLQAFVLVNAGQAIAHAITTPIG"
     misc_feature    complement(17963..17965)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(18944..18946)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19016..19018)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19058..19060)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19312..19485)
                     /locus_tag="MMAR_RS29670"
     CDS             complement(19312..19485)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MMAR_RS29670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_015354679.1"
                     /transl_table=11
                     /translation="MDVTRNRRLFTLRALGAVVAATIAAAALSSCSSSGDPGIQDPTIQ
                     GAASSADLINAG"
     misc_feature    19516..19531
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.41"
                     /tool="antismash"
     misc_feature    19771..19785
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.27"
                     /tool="antismash"
     misc_feature    19815..19824
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.89"
                     /tool="antismash"
ORIGIN
        1 tcgcccgatg atcttgggtg ccggcccgcg gctcgagtgt ctcgtgggtg gggtggggcc
       61 gggtcgaggg cgcttgattg gctgttctat ggtcagttca gccgccgctt tgacctgcct
      121 aaccgcaggc gggtattgtg gttgctcgtg cctggcggcc tacagcgcct gacgtgaggg
      181 cgtggatgcc gggccaattc gcatgtccat gtttttggcg gccaagcgga ttgagttcgg
      241 ggccatcgta tgcgacacac ccggccgcgg ggtgcagctg cggggcataa ctgcagtaca
      301 ggaacttcaa aatagcgcgg gcagtgttac ggggcccgca gcaaacgtga acagcgagaa
      361 agaaagccgg tagatgccaa ccattcagca gctggtccgc aagggtcgtc gggacaagat
      421 cggcaaggtc aagaccgcgg ctctgaaggg cagcccgcag cgccgtggcg tatgcactcg
      481 cgtgtacacc accaccccga agaagccgaa ctcggcgctt cggaaggttg cccgtgtgaa
      541 gctgacgagt caggttgagg tcacggccta catcccgggc gagggccaca acctgcagga
      601 gcactcgatg gtgctcgttc gtggtggccg ggtgaaggac cttcccggtg tgcgttacaa
      661 gatcatccgc ggttcgctgg acacccaggg agtcaagaac cgcaagcagg ctcgcagtcg
      721 ctacggcgcc aagaaggaga agagctaatg ccgcgcaaag ggcccgcgcc caagcgtccg
      781 ctggtcaacg accccgtcta cgggtcccag ctggtcacgc aactggtgaa caaagtcctg
      841 ttgcagggga agaaatcgct cgctgagcgc attgtttatg gtgcgctcga gcaggcgcgc
      901 gacaagaccg gcaccgatcc ggtcatcacc ctcaagcggg ctctcgacaa cgtcaagccc
      961 gcgctggaag ttcgcagccg ccgcgtcggt ggtgcgacct accaggtgcc cgtcgaggtg
     1021 cggccggacc ggtcgaccac gctggcgctg cgctggctgg tcggctactc gcggcaacgc
     1081 cgggagaaga ccatgatcga gcgcctggcg aacgagatcc tggatgccag caatggcctg
     1141 ggtgcctccg tcaagcggcg tgaggacacg cacaagatgg ccgaggcgaa ccgcgccttt
     1201 gcgcactacc gctggtaaga gtcctggggc gagctgtcgg agcaaacccg gcggcaactg
     1261 atagctaact aagcaaccga aagagtggga agacttctgt ggcacagaag gacgtgctga
     1321 ccgacctgac caaggtccgc aacatcggca tcatggcgca catcgacgct ggcaagacca
     1381 cgacgaccga gcgcatcctc tactacaccg gtatcagcta caagatcggt gaggtgcacg
     1441 acggcgccgc caccatggac tggatggaac aggagcagga acgcgggatc accatcacct
     1501 ccgcggccac cacctgtttc tggaacgaca accagatcaa catcatcgac accccgggcc
     1561 acgtcgactt caccgttgag gtggagcgca gcctgcgtgt gctcgatggt gccgtggccg
     1621 tgttcgacgg caaggaaggt gtcgagccgc agtccgagca ggtgtggcgc caagccgaca
     1681 agtacgacgt cccgcgcatc tgcttcgtca acaagatgga caagatcggc gccgacttct
     1741 acttctccgt gcgcaccatg gaggagcggc tgggcgccaa cgtcatcccg atccagctgc
     1801 cggtcggttc cgagggcgac ttcgaaggcg tcgtggacct ggtcgagatg aaggccaagg
     1861 tgtggagcgc cgacgccaag ctcggcgaga agtacgacgt cgtcgacatc cccgcggact
     1921 tgcaggagaa ggccgacgag taccgcacca agctgctcga ggccgtcgcc gaaaccgacg
     1981 aagcgctgct ggagaagtac ctcggcggcg aagagctcac cgaagccgag atcaagggcg
     2041 cgatccgcaa gctgaccatc acctcggagg cctatccggt gttgtgtggc agcgcgttca
     2101 agaacaaggg tgtgcagccg atgctggacg ccgtcatcga ctacctgccc tccccgctgg
     2161 acgtgccggc cgccatcggc cacgtgccgg gcaaagagga cgaggaggtc gtgcgcaagc
     2221 cctcgaccga cgagccattc tcggcgctgg cattcaaggt cgccacgcac cccttcttcg
     2281 gcaagctcac ctacgtccgg gtgtactcgg gcaaggttga ctctggcagc caggtcatca
     2341 actccaccaa gggcaagaag gaacgtctgg gcaagctctt ccagatgcac tccaacaagg
     2401 agaacccggt ggagaccgcg tcggcgggtc acatctacgc ggtgatcggc ctcaaagaca
     2461 ccaccaccgg tgacacgctg agcgatccga acaaccagat cgtgctcgag tcgatgacct
     2521 tccccgatcc cgttatcgag gtcgccatcg agcccaagac caagagcgac caggagaagc
     2581 tcagtctgtc gatccagaag ctcgccgagg aggaccccac cttcaaggtg cacctggatc
     2641 aagagaccgg ccaaaccgtc atcggcggta tgggcgagct gcacctggac atcctggtgg
     2701 accgcatgcg ccgggaattc aaggtcgagg ccaacgtcgg caagccgcag gtcgcctaca
     2761 aggagaccat caagcggctg gtggaaaagg tcgagttcac ccacaagaag cagacgggtg
     2821 gctccggtca gttcgccaag gtgctgatca gcatcgagcc gttcaccggc gaagacggtg
     2881 caacttacga attcgagagc aaggtcaccg gtggtcgtat cccgcgggag tacattccgt
     2941 cggtcgacgc cggtgcgcag gatgcgatgc agtacggcgt cctggccggc tacccgctgg
     3001 tgaacctgaa ggtcaccctg cttgacggtg ccttccacga ggtcgactcc tcggaaatgg
     3061 cattcaagat cgctggttca caggtgctca agaaggccgc ggcagcggcg cacccggtga
     3121 tcctggaacc gatcatggcc gtcgaggtca ccacgcccga ggactacatg ggcgatgtga
     3181 tcggcgacct gaactcccgc cgtggtcaga ttcaggccat ggaggagcgg agtggtgctc
     3241 gcgtcgtcaa ggcgcacgtg ccgctgtcgg agatgttcgg ctatgtcggc gacctgcggt
     3301 ccaagactca aggccgggcg aactactcca tggtgttcga ctcgtacgcc gaagttccgg
     3361 cgaacgtgtc gaaggagatc atcgcgaagg cgacgggcga gtgagccacg agcacggagc
     3421 ccagcagtag gtaaaggccg gcaagccggg agcctggcgg tatgagttgg gaacccgagc
     3481 aaggcaccag ggtggcaggg agtaacctgg ctcggttact ccgcggcata agtgaaaaca
     3541 tcaacaacac actgcttttt taagcaccaa cagtccagga ggacacagaa gtggcgaagg
     3601 cgaagttcca gcggaccaag ccccacgtca acatcgggac catcggtcac gttgaccacg
     3661 gcaagaccac gctgaccgcg gctatcacca aggtgttgca cgacaagtac ccggagctga
     3721 acgagtcgcg cgcgttcgat cagatcgaca acgcgcccga agagcgtcag cgtggtatca
     3781 ccatcaacat ctcccacgtg gagtaccaga cggagaagcg gcactacgcc cacgtcgatg
     3841 ctccgggtca cgccgactac atcaagaaca tgatcaccgg tgcggctcag atggacggcg
     3901 cgattctggt ggttgcggcc accgatggtc cgatgccgca gacccgtgag cacgtgctgc
     3961 tcgctcgcca ggtgggtgtg ccctacatcc tggtcgcgct caacaagtct gacgcggtcg
     4021 acgatgagga gctgctcgag ctggtcgaga tggaggtccg cgagttgctg gccgcccagg
     4081 agttcgacga ggacgcaccg gtggtgcggg tatcggcgct caaggcgctc gagggcgacc
     4141 cgaagtgggt cgagtccgtc gagcagctga tggacgcggt ggacgagtcg atcccggacc
     4201 cggtccgcga gaccgaccgc ccgttcctga tgcccgtcga ggacgtcttc accatcaccg
     4261 gccgcggcac cgtggttacc ggtcgtgtgg agcgcggcat catcaacgtg aacgaggaag
     4321 tcgagatcgt cggcatccgt ccgaccagca ccaagaccac ggtcaccggt gtggagatgt
     4381 tccgcaagct gctggaccag ggccaggccg gtgacaacgt cggtctgctg ctgcgtggta
     4441 tcaagcgtga ggacgtcgag cgcggtcagg tcgtcgtcaa gcccggcacc accacaccgc
     4501 acaccgagtt cgagggccag gtctacatcc tgtccaagga cgagggcggt cggcacacgc
     4561 cgttcttcaa caactaccgt ccgcagttct acttccgcac caccgacgtg accggtgtgg
     4621 tgacgctgcc ggagggcacc gaaatggtga tgcccggtga caacaccaac atctcggtga
     4681 agctgatcca gcccgtcgcc atggacgacg gtctgcgctt cgcgatccgt gaaggtggcc
     4741 gcaccgtcgg cgccggccgg gtcgtcaaga tcatcaagta gatccaaccg gatccagcac
     4801 cagtcaaaac caggcccgga tagccgagat cggctatccg ggcctggtgt ttgtctgccc
     4861 gccgccgaat tgcctgcacc agaaccggat cacctttgcc gccgtgcaac gtgcgcggtc
     4921 ggcggccatc gatcgcggca ccggcgccac ccgacggtcg tgtttggtct tcgcccagtt
     4981 caaagggcgc taatctggca tcaatttccc ggcgacccga ggagaacaag atgctggcgc
     5041 gctacctgaa gatgcagttg ctggtgctgc tttgcggcgg tctggtcggg ccgattttcc
     5101 tgatcgtcta ctttgccctc ggcgtgggca gcctgttgtc gtggatgttg tacgtgggcc
     5161 tgctcatcac cgtcgcggat gtgttgattg cgctggcgct gaccaatttc ggcgcgaaat
     5221 cggctgccaa gtccgctgag ctcgagcaga gcggagtgtt ggcgctggcc caaatcaccg
     5281 gcctgaccga gaccggcacc cggatcaacg accgccccct ggtgaaggtc cacctgcata
     5341 tctcgggtcc tggaatcgcg gcgttcgaca gcgaagaccg ggtcattgcc agcgtgaccc
     5401 gcctcggcaa cctcaccgcg cgcaaactcg tcgtgctggt caaccccacc acccaggaat
     5461 acctgatcga ctgggagcgc agtgcgctgg tcaacggcct ggtcccggca cagttcaccg
     5521 tcgcagaaga caacaggaca tacgacctca gtggccaggc cggtccgttg atggagattc
     5581 tgcagatcct caaggccaac gggattccgc tgaaccggat ggtggacatc cgatcgaatc
     5641 cggtcctgcg ccaacagatc caagcggtgg tgcgccgtgc ggcccagcag cagatgcccg
     5701 cgggtgcggc ccagccgagt gcggccccac aagcctccat cgccgagcgc ctccaagagc
     5761 tggaatcgct gcatgccagt ggggcgctga acgcgcagga gtacgccagc aggcgtgccc
     5821 agatcatctc cgagatctga gccgaatcct ggcgccccgc caggcggggc gggctggtgg
     5881 cgtgccgggc gccacgacat gccagcgccg gcgggcgcgt tagaacacgt ttcagtttcg
     5941 ctgctagcct gacattcggc gagaggggtg taggtggctg cacagactgg atcactggat
     6001 ggacgggtgg cctttgtcac cggggcagcg cgcgcgcagg ggcgatcgca tgcggtgcgg
     6061 ttggcgcgcg agggtgccga catcatcgcc atggacatct gcggaccggt atccgagacc
     6121 atcacctacg caccggccac cgcggcagac ctcagcgaga cgatccgcgc ggtggagagc
     6181 gaaggtcgca aggtactagc gcgccaggca gatgtccgcg acagtgcggc gttgcagcaa
     6241 ctggttgccg atggggtcga ggagttcggt cggcttgacg tggtggtagc caatgccggg
     6301 gtgttgggct ggggccggct ctgggaactc accgatgagc agtgggacac cgtgatcggc
     6361 gtcaacctca gtggcacctg gcgaacgctg cgcgcggcgg tgcccgcgat gatcgaggct
     6421 ggcaatggcg ggtcgatcat cgtggtcagc tcctcggcag gtttgaaggc cacaccgggc
     6481 aacggtcact atgcggcgag caagcacggg ctcgtggcgc tgacgaacac tctggccatc
     6541 gaactcggcg agtacgacat ccgggtcaac tccattcatc cgtactcggt cgagacgccg
     6601 atgatcgagc cggacgtgat gatgcaggtg ttcggcgagc atccccgctt cttgcatagc
     6661 ttcccgccaa tgccattgca gtacaaaggt ttaatgacct ccgaggaggt ctccgatgtc
     6721 gtggtctggc tggccggcga cggctctggc acgctgagcg gggcacagat ccccgttgac
     6781 aagggcgcct tgaagtactg acacgccatc gtgtatgaac accacgtgac cagtagtgaa
     6841 ggtgtgaccc aggatcccgg cgccacggcg gcaaacggga ttgtgatcat cggcggcggg
     6901 ctggcggccg cccgcaccgc cgagcagctg cgtcgggccg gctatgaggg tcagctcacc
     6961 atcgtcagcg acgaggtgca cctaccctat gaccgcccgc cgctgtccaa agaggtgctg
     7021 cgcagcgagg tcgacgacgt gtcgctcaag ccacgcgagt ggtacgacga gaaggacatc
     7081 gccctgcggc tgggctcggc ggcaaccggc ttggacaccg ccgcgcaaac cgtgacgctg
     7141 gccgacggga cggtgctcgg ctacgacgag ctggttatcg caaccggctt ggtgccccgg
     7201 cgcattccgg ccttccccga actcgagggc attcgggtgc tgcgctcgtt tgacgaatgt
     7261 atggcgctgc gcagccacgc ctcggccgcc aagcgcgcgg tcgtgattgg tgccggtttc
     7321 atcgggtgtg aggtggcggc cagtctgcgc ggcctcgggg tggaggtggt gctggtcgaa
     7381 ccacagccaa cgccgctggc ggcggtgctc ggcgagcaga tcggcgagct ggtggcgcgg
     7441 ctgcatcgta gtgagggcgt cgatgttcgc accggggttg gggtggctga ggtccgcggc
     7501 gacggccatg tcgacaccgt ggtgctggcc gacggcacgc aactcgacgc cgatctggtg
     7561 gttgtcggca tcggttcgca cccggcgacc gggtggctcg acggtagcgg catcgcggtc
     7621 gataacggcg tggtttgtga cgccgccgga cgtaccagcg cgcccaacgt gtgggcgctc
     7681 ggtgatgttg catcctggcg ggatcaaatg ggacaccaag tccgcgtgga acattggagc
     7741 aatgtcgccg atcaggcacg ggtagtggtg ccggcgatgt tggggcgcga agtgtcctcg
     7801 aacgtggtgg tgccctactt ctggagtgac cagtacgacg tcaagatcca atgccttggt
     7861 gagccgcatt cgaccgatgt ggtgcacctg gtcgaggacg acggacgaaa gttccttgcc
     7921 tactacgagc gtgatggtgt gctcgttggc gtggtcggtg gcggggtgcc gggcaaggtc
     7981 atgaaggtac gtgccaaaat cgccgccgcc gtgcccatct ccgagatgct ggacgaatcg
     8041 cagggctaga catccgcgcg gataccggcg cctggcgccg gcccgggtgg cccgcttgtg
     8101 cggtggccga cgtcaaccga aacttgggcg atggcgcgcc gagaaagcta ctgccagttc
     8161 accggtggcc cgtgcggatg acattggcct agaacccggg cctcgccgga cggccagctg
     8221 gccagacgta ccaggaactt gagccgaccg ccctcgtcgc gtgcgggctc gagggtgagg
     8281 tgggcgaagg gtgagcgggg gccggcctgt gcgcccagct ccgcgacccg gtcgcggatc
     8341 gcggcacgct cctgggcggc caggtattgc caggtgatcg aatgccacaa caccgtcagc
     8401 gtttcgtctt gcagcgtcag cccggcgacg ccgtcggcgg cggtcttgcg ttcgagctgt
     8461 gccgggacgt cccgcgcgac ggcgatcgcg ccgcgcagcc gcttcatccg ggcgtgctgg
     8521 tcgggccaga catagctcaa cacggtcatt tcgccgtcag tgccgcagat atcgatgggt
     8581 gcgatgtcgt agccgtgacg ttcgacgatc tgtagtgcca gcgcgggcgg caactcaccg
     8641 cgccaagcat cttcgataat caccggggag tcgatcgggc cccacgtcat tccggcgtag
     8701 cggtagtggt agcggtcagc ccgcaggttc agtccggcac tggccccaat ctcgaaaagt
     8761 cttaccggaa agttgaattc gtggcgaatg tgcagcaggc caccgatcag tgccgccgac
     8821 cggccgactt cgttggtctg tgggggctgg tcaagagcgc cgcgcaaggc ttcggtgtgg
     8881 ttggccgcga cgagttcgat ttcgggccag gcgctcttgg cgtcccagct gccgtcagtg
     8941 ctgggatacc agcggcgcaa cgtgggtgcc cggccgtcga gcaccattcg gtgcaggccg
     9001 ccgagcagcc gcagcggggt ggcataccgg gacgggtcgt cctcgtggcc ggccaggatg
     9061 ggggcgaata cgccgcccgc ttcgacatcg gcggcgacca actcaaacaa ctcgccatac
     9121 atcggcgatc cggatcgggc gcagaaccgg ccctgtgacc gcagggtgtg cagcagatgc
     9181 tcgatacccc cactctttgc ctcctgcatc agtccagctt ctccaagccg gcgccaacga
     9241 cgtcgaaggc attcccgagc gcttccggta acgagacgga ttcgtcgctg agccagtgtt
     9301 cgtaggcgct caacgcgacg ccgagcatcg tccaggcaac cgtctggggc accaggtcgg
     9361 tgggtttgac actgagtcgt cgggccacga aaccggcgat caccgcacgc cagccggcat
     9421 acatcgtcat cgaatacgcc tgcagctcag cggtttgcag aatgatgcgc atccgctggc
     9481 gatgccgaat ggtctcggat tcgtcgtagg tgttgaacgc caacagcgcc tcccgcagcg
     9541 ccttgcccaa ccgaacgtgc ccgtcgatgc gctcgagcag atcctgcagc tgggcaaggt
     9601 gggtgtcgaa gtcgccccag gggatcgcgt tcttcgaggc gtagtagcgg aacagggtgc
     9661 gtcgggcgat gccggcggct tgggcaacgt cgtcgacgct gacctcggcg aaggtgcggg
     9721 cggcgaacaa gtcgatggca acgtcggcga tgtggcgctt ggtcgtcgag gggcgccgac
     9781 cggcccgcga ctcatgcgcc atcggttcca cccttccatt tcggcactcg atgccatatt
     9841 ctggcatcgc tgacgctgac tgtgactagc gccaccgctc attgtcacct cattgttaac
     9901 gcccatgacg aaaggcaact cacatggacc gcgaaactga agccgagact gccgagctgg
     9961 tcaccgagtc gctggtcgaa gaggtgtcca tcgacggcat gtgcggggtc tactgaccgt
    10021 gcccgcgccg gcgcaggcgg cggccggggc cggggctttc gaccctgatc ggggctggcg
    10081 gctgcacccg caagtggcgg tgcggccgga gccgtttgga gcgctgcttt atcacttcgg
    10141 cacccgcaag ctgtcatttc tgaaaaatcg caccatcttg gcggtcgttc ggtcactggc
    10201 cgaccatccc gatgttcgct cggcctgccg cgccgcgggg gttgatgact ccgaacacgc
    10261 tccctacttg cacgcgttgt cggttctggc cggctctcac atgctggttc cccaggaggc
    10321 tgatcaatga cgaccgcagt accgcggctg atcgagcagt tcgagcatgg gctcgacgcg
    10381 ccgatttgtc tgacgtggga actgacctac gcctgcaatc tggcctgcgt gcattgcctt
    10441 tcgtcctcag gcaagaggga tccgggtgag ttgtccaccc ggcaatgcca ggacatcatc
    10501 gacgagttgg aacgcatgca ggtgttctac gtgaacatcg gtggtggcga acccacggtg
    10561 cgtccggact tttgggagct ggtggactac gccaccgcac accacgtcgg agtgaagttc
    10621 tctaccaacg gggttcggat caacccggag gtcgccgcgc ggctagctgc cagcgactac
    10681 gtcgatgtcc agatctcgct cgacggcgcg accgccgaag tcaatgacgc cgtccggggt
    10741 gccggatcgt tcgccatggc ggtgcgcgcg ctcgagaacc tggcggccgc gggtttcgcc
    10801 gacgcgaaga tctccgtggt ggtgacccgg cacaacgtcg gccaactcga tgatttcgcc
    10861 gcgctggcgg accgctacgg tgccacgctg cggatcaccc ggctacggcc gtcggggcgc
    10921 ggtgcggacg tctgggagga attgcacccc accgcggccc agcaggtcgc gctctacgac
    10981 tggttggtcg ccaagggcga acgggtactg accggtgatt cgttctttca cctggcgccc
    11041 ctggggtcct cgggtgcgct ggccggtctg aacatgtgtg gagccgggcg ggtggtgtgc
    11101 ctgatcgatc cggtgggtga cgtatacgcc tgcccgttcg ccatccacga ccgcttccta
    11161 gctggaaacg tcctgaccga cggcggtttt gaccaggtct ggaagaacgc gccgttgttc
    11221 cggcagctgc gggagccgca gtcggcgggc gcctgcggca gttgtgggca ctacgacagc
    11281 tgccgcggcg gttgcatggc agccaagttc ttcaccggtc ttccgctcga tgggcccgac
    11341 cccgagtgcg tccaggggta cggtgcgccg gcactggcgc aggagcggca tgcgccgcgt
    11401 ccgcgggtgg atcactcgcg gggcagccga gtgagcgcgc cggtgcccct gacgctgacg
    11461 acgcgcccgc ccgcgcgcct gtgcaacgaa agtcccgtgt agtcatggcc gatgagtggt
    11521 ttgaaacggt cgccatcgcc cagcagaggg cgaaacggcg tctcccgaaa tctgtttact
    11581 catccctgat ttcggccagc gaaaagggaa taacggtggc cgacaacgtg gcggcgttta
    11641 gcgaactcgg cttcgcaccg catgtcatcg gcgcagctga aaagcgcgat atgtcgacca
    11701 ccgttatggg acaggatatt tcgatgcctg ttctcatctc gcccaccggc gttcaagcgg
    11761 tgcatcccga cggtgaggtg gccgttgccc gcgcagcggc cgcacgtggc acggcgatgg
    11821 gcctgtcgtc gtttgccagc aagacgatcg aagatgtcat cgccgccaac cccaaaatct
    11881 tctttcagat ctactggctc ggcgggcgcg acgcgattgc cgagcgtgtc gagcgggccc
    11941 gtcaggccgg agcggtgggc ctgatcgtca ccacggactg gacgttctcc cacgggcgtg
    12001 actggggcag ccccaagatc cccgaacaga tgaacctgcg gaccatcctg cgcctgtcgc
    12061 cggaggcgat tgttcgcccc aggtggctgt ggaagttcgg taagacattg cggccaccgg
    12121 atctgcgggt gccaaatcag gggcggcgcg gcgaacccgg tcccgcgttt ttcgccgcgt
    12181 acggagaatg gatgggcacc ccgccgccga cctgggatga cattgcctgg ttgcgtgagc
    12241 tatggggtgg acctttcatg ctcaaggggg tcatgcgggt cgacgacgcc aaacgggctg
    12301 ttgacgctgg agtttcggcg atttcggtgt ccaaccacgg tggaaacaac ctcgatggga
    12361 cgccggcgtc gattcgggcc ctgcccgccg tggcggcagc ggtcggcgac caggtcgagg
    12421 tgctgctgga tggcggcatc cggcggggga gcgacgtggt caaggcggtt gcgctgggtg
    12481 cccgggcggt gctggttggc cgcgcctacc tgtggggact ggccgccaac ggtcaggccg
    12541 gcgtcgagaa cgtccttgac attctgcgcg gcggcatcga ctcggcgctg atgggtctgg
    12601 gccatagttc gatccatgac ctgcggtcag acgacattct gatccccgcc gatttcgtcc
    12661 ggcgcctggg cgggtaggaa tccgggcctg ccttaccaca aagttgagcg gccgtatcaa
    12721 gaatctgtga ggtcgggcgc cgccgccggt ccggcgagtt gagttcgggc cggtcaggcg
    12781 tcgacccgaa gaaaaaaatc cgtagaaaag gtaacaatcg gtgcacgcca ggtgaattcg
    12841 tcctaccatc ggcgagtgcc cgtactcggc gaattgggga cttcgacgtc gagccagcta
    12901 ccaagcacct cgccgtcaat attgatcccg ctggggtcaa ctgaacagca cggaccgcac
    12961 ctgccgttgg ataccgacac ccggatcgcg accgcggtcg gccgggcggt tgccacgcgc
    13021 atgcacggcc gcctgactca gtgtcaaccc ggttggctgt tggcgccccc gatcgcatac
    13081 ggtgccagcg gtgagcatca gagttttgcc ggaacgatct cgatcggcac cgaggctctg
    13141 agggtgctgc tgctcgagta cgggaggtcg gccgcctgct gggctgatcg gctggttttc
    13201 gtcaacgggc acggtggcaa tgtcgaggcc ttgcgtggtg cggttcggca gctgcgcgcc
    13261 gaaggtcgcg acgccggatg gtctgcctgc ggctcggcgg gcggtgacgc tcatgccggc
    13321 catactgaaa catcagtgtt gctgcatatt tcaccggagg tggtgctgac cgaccggctg
    13381 agtgcgggga acgcggcgcc gctggccgaa ttgctgccgt cgttgcgccg cggtggcgtc
    13441 gcggcggtca gcccgatagg tgtgctgggc gatccgacca cggcgaccgc agtagaggga
    13501 aggcgaatct tcgcagagat ggtcgatgat tgcgtgtctc gaattgcccg gtggaccccc
    13561 gggcccgacg ggatgctgac atgacgcaac cccgactacc tgacgggttc gcggttcagg
    13621 ttgaccgtcg cgtgcgggtg ctcggcggcg ggtcggccct gctcggtggg tcgccgactc
    13681 gattgctacg tctggcgcct gccgcccagg acatgctctg tgacggccgt ctgaaggttc
    13741 gcgacgacat cagcgctgag ctggcccgca cgctgttgga cgcgacggta gcgcatcccc
    13801 ggccggcgag cgggccatcg catcgcgatg tcactgtcgt gataccggtg cgagacaatg
    13861 catccggcgt gcgccggctg gttgcctcat tgcgtggcct gcgcgtgatc gtggtggatg
    13921 acgggtcgtc gagcccggtc gagctggagg acttcgcggg ggcgcactgc gatgtcgaag
    13981 tgctgcacca ccggcgcagc aaggggccgg ccgccgctcg caacaccggg ttggcagcct
    14041 gcacgaccga gttcgtggca tttctggatt ccgacgtggc gccacgccgc ggctggctcg
    14101 aggccctgct cgggcacttc tgcgatccca ccgtggcgtt ggtcgcgcct cgcattgtgg
    14161 gcctggcgcc gagtgagaat ctggtggccc gctatgaggc cgtgcgttca tcgctggacc
    14221 ttggtcagcg ggaagcgccg atattgccgc acagcccggt gtcctacgtt cccagcgccg
    14281 cgatcatctg ccgttgctcc gccatccgtc aggtcggcgg gttcgacgaa accatgcact
    14341 ccggtgagga cgtcgatctg tgctggcgcc ttatcgagtc cggtgcccgg ctgcgctacg
    14401 agccgattgc actggttggt catgagcatc ggacccaatt gcgtgcctgg atcgcgcgca
    14461 aggcgttcta cggggggtcg gcggcgccgc tgtcggtgcg ccacccggac aagaccgcgc
    14521 cgttggtgat ttccggttgg gccctgactg cctgggtgct gatgtcgctg ggtacccgag
    14581 caacgcagct ggcctcgctg atcatcgcgg tgttgacggg ccggcgaatt gccacggcac
    14641 tgcgtagtgc ccaaacctca tcgtgggatg tggtggtggt cgcggcgcgc ggattatggt
    14701 cggccgcact gcagttggcg tcggccattt gccggcatta ctggccggtg acattgatcg
    14761 cagtcattgt gtcccggcac tgtaggcggg tcgtgctggt ggctgcggtc atcgacggtg
    14821 tggtcgactg gctgcgccgc agagaggacc ccgacggcga ctccgaaccg attgggttgc
    14881 tgacctacct actgctcaag cgcattgacg acctcgccta cgggctcggc ctgtggtacg
    14941 gggtgatgcg tgaacgcaac gcgggcgcgc tcaagccgca gatccgacgg taacggcggc
    15001 cttgaccgcg gcgctgcgcc acagtgatgt cctgatcgtc ggcgccggaa gcgccggatc
    15061 ggtcctggcc gcgcgtcttt ccgccgatcc gagttgcgcg gtgacgttgg tcgaggcggg
    15121 gcccggcctt gctgatccac ggttgctggc tcaaactgcc aacgggctgc agctaccgat
    15181 cagtgctgac agtccgttgg ttcagcgcta tcagagccag ctcacggatc atccagttcg
    15241 tcgaattccg atcctgcgcg gggcgacact tggcggctct ggggcggtca acggcgggta
    15301 cttctgccgc gggctggcgc gggatttcga tggtgccgcg ataccgggct ggtcatggtc
    15361 gcaggtgctc ccacacttcc gggcgatcga gaccgacctg gacttcgaca cgcccgtgca
    15421 tggccgcacg ggtcccattc cggtgcgccg gacccgcgat cagaccggag tcacgcagcg
    15481 attcgtcacg gccgctcagc gtgccgggtt cggctggatc gccgatctca acgatgttgg
    15541 tccggatatc gccgcgggcg tgggcgcggt cccgctgaac atcgttgacg gggtacggac
    15601 cgggtcgggg gccgcatatc tgctgccggc gctgggccgc cccaacctga ccctgctgga
    15661 agaaacccgg gcccagcaag tgcgcttttc cgccgcgacc gcggtgggcg tcgatgccgt
    15721 cggtccgagg gggccgatga ctctgtgggc ggatcgaatt gtgctttgtg ccggagcaat
    15781 tggatccgca cacctgctga tgctctcggg tatcggcgac catgcgatgc tgcggtccgc
    15841 cggggtcccg gtggtgcagg cgttgcccgt cgggatgaat tgcagcgacc atcctgaatg
    15901 ggcgttgccg accacatgga ccgtcgccgc cggacggccg gtgttggagg cggtactcaa
    15961 taccgctgac ggcatcgaaa ttaggccata cacaacagga ttcgcagcaa tggcgggcgc
    16021 agctgctaag gggcatcggg actggccgca cctcggagtg gcgctgatgc gaccgcggtc
    16081 tcgcgcccgg gtcaccttgg catcgcccga cccttcagtg cctccccgga tcggacacca
    16141 ttacgacagt gagccggccg atgtcgcggc gctgcagcgg gggaccgagt tggcgcgcga
    16201 gttagcgggg tcggcagtgg cgggggagcc gggatggtcg acatcgcagc atctgtgcgg
    16261 tagcgcaccg atgggtgtcg atgccgaccc gacggccgtc gtcgatcccg agtgccgggt
    16321 gcgtggtatc gaaaaccttt gggtggttga cggatccatc ctgccgctga ttcccagccg
    16381 tggtccgcac gcaacaatcg tgatgctggg tcaccgggcg gcggaattca tcggctaacc
    16441 cgcgagttga tcatcggccg cgtcggctcg ctaccgagcc ggcggcgctc cggggcgtgg
    16501 tgattgttgg tgttcggctg accggagtgg ctcacgccgt gcagcaggag ttcggtaatc
    16561 atgggcgcaa agtcgcgcgg ggccgcccgt ccggtgttta tcgaccagcc cgcgccggag
    16621 accaggctgt agaacgcttc ggtcagccac ccggccgcca ggtcgggccg gaactcgccc
    16681 tggcgctgac cgcggaggaa cagctccttg atctcgctgt cgatttccag ccagccctgc
    16741 ttgagctcat tggtgtcgga atcctgactg taggcgtaga gcaacgtcag gtacccggat
    16801 accgattcgc atgccgccac cagcctccgc agcgcctcgg tagccgatcc ctcttgccag
    16861 cgagcgcttt tcagcgcttc gcgcatctgg ccgaacgcga gctgctctag cgcatcgatc
    16921 agcgcggcgc ggccggcgaa gtagcgatgc aatgtcgcac ggctgacgcc gattgccgcg
    16981 gcgatctcgt cttgggttgc gttaggcctc cggccgagga actctgcggc ggctcgaaga
    17041 aggcgttcgt gatccagtgc catgagacga tagtacatca tctgagacaa aattgtctca
    17101 gcgaatgcaa ttttgtctca atctgctggg ttcgtgcggg tggcgggctc cgggcgctgg
    17161 gtgggcggcg tggtccccga tctgcgtccg taactgatca gccgatgggc gtggtgatcg
    17221 catgtgcgat tgcctggccc gcgtttacca ggacgaaggc ttgcaggagg ccggccacgg
    17281 taatcagggc tacgtccgcc gccagggggt atccgacggc gttgacgaaa cccatcgggt
    17341 cgccgttggc gacttgttgg atgccgtcga ggaagagatt gatgttatag gacggcacgc
    17401 tggtgatggc ggcattggcg atgtcggcag tgggcagcag ggctgcgtag ctggcggcac
    17461 ccacctcggt gatggtgttg gcaacctggc tattggccgc ctgtaggtcg tcgatgatgg
    17521 tgttgatcga gaccatcggc gcggcgggtc cggtggtggg agcggcctgc ggattgccca
    17581 ccggtgaact ggacccgttg gtgatctgcg gtagatccag atggctgatg tggtagccga
    17641 agtcgtgaat tccttgctgg gtgccggcgg cgagtgcgtc ggcgatggtc agcgggctca
    17701 cctcgggcca gagcccgaag ggggtagcga cgttgggcgg tgaggtcgag tatccgtagg
    17761 cggggtcgcc gtagcccaga ttgacgatga ccttgaggtt gggctggacc aggtcggcga
    17821 gcgggtctcc gagtacgggc agtgctcgta gtggttcgag cagcgggagg tcttcggtgc
    17881 ggatcacgta gtagtcggtc atggtcgggc ccaccgtgtt ggtcaggtgc acggccgcat
    17941 cgatctgggc gggagttagg aataagtagt cggtgtgcac gtagtaggca cccgccagcg
    18001 cgttgagggt ggataccagg ttgagcgggt agcgcgggaa gtcggcgacg ccgtcgtact
    18061 cgagggtgta aatcctggtc gggtagagat tgtccggtgt ggcgccgctg gcggtgatcc
    18121 ccagactcgg cagcgacagt cccgggaacc gggtggccac tccgccattg ggattgttgg
    18181 ggtcacccac cagcgtgaac gagagctgat ctggcgtggg cgggttgatc gatgcggcga
    18241 gcttggtcat cgtcagcgac gagatggtgg cgctctggga gtagccgaac acggtgacgt
    18301 tgttgccggc ggtgatctgc tcgcggatcg cgctctccag gatgaccacc ccccgggcca
    18361 ccgaggtgtc aaacgtcagg ttcttgaccc cggtcaccgg gtagaggcct tcgggggtga
    18421 acaacgcctg cgcgaccgcg cccccaacac tgcggccgat atagagggag ttggcgagtt
    18481 gcacgtagcg ccgcgagggc atcggaatgc cactgccgcc catcacttcc gcaatcgttt
    18541 gtgcggcagc aacattcgtg ccgatggaac tggtgttcgc ggcggttgcg ctgaggccgg
    18601 aggcccggga aagcccggcg ccggcactgc cgcccacagc gcctacgatc gtgcccaatt
    18661 gctggctcca gggtgccaac tgagcggcca ccgccgcggc gccgccgtaa tagccggcca
    18721 tggccgagac atcctgggcc cacatctgct cgtatgagga ttcggcggcc gcgatcgccg
    18781 gcgcgttctg gccgaacagg ttggtcatca ccagcgacgc cagctgtgca cgattggccg
    18841 cgaccgcgac cggatgcacc gtggccgcca gggcggcttc gaattcggcc gccgctgcgc
    18901 gcgcggcggc ggccgccccc gcggcatgta gggccgaggt gcgtaaccag ccgacatagc
    18961 ggccggccgc caccgtcatg gccgccgacg ccggaccctg ccacaccccg gctgctaact
    19021 ccgacgtgac cgacccgaag gagcccgccg caccggataa ctcggcagac agcccgtccc
    19081 aggccgtcgc ggcggccagc gtcggcgccg atcccgcgcc accaaacaac cgagccgaat
    19141 tgatctccgg gggcaacacc gaaaaactcg ccaacatcag cacggccctt ccttggtcca
    19201 gcggtcagca ccccatagcc cgccaacctg ctcaaaacgc aactctcatc cgatgcggct
    19261 gagaaacaac gcatcggatg agagtgcgaa cgacctcgag ttagcccgca gctaccccgc
    19321 gttgatcagg tccgcggaac tcgcggcgcc ctgtatcgtc ggatcctgga tgcctggatc
    19381 ccctgagctg ctgcaacttg acaacgccgc agcggcgatc gtggcggcta ccacggcgcc
    19441 cagcgcgcgg agtgtgaaca gtcgcctatt tcgcgtaacg tccatcagtc attcctcctt
    19501 ttgtcggtgc ggcgaattgg tgtacacctg ccggaaagct aactccgaaa caatgcaacc
    19561 aggcgccgtt atttaagatt tcagccgcaa ttggagaccg cgatgtcacg tttgcaacac
    19621 cggcgtctcg caatggacgg ggctggttca taacgcgccc tatcagccga aacgcttgcg
    19681 gcccaacgtg agctgccgct atatttcgat ctgcagtcgg gggaatgaat ttttggtaca
    19741 ccaaattttg tggcggcccc gcgccaggat tgaatcacgc tttcaagcgg gaattcatgc
    19801 agcgaaagtg tgctgaaggc gaccattgtc atttcgctgc tgcttcggaa gtcgactcga
    19861 taagcaaggc ggtactcggc gcgagtgctg gcccgcggcc agaccgggag ggttgggcga
    19921 tgaacttttc agtgttgcca ccggaggtca actccgcgct gatattcacg gggcccgggg
    19981 cggagccgat gcgcacggct gcgacggcct ggggcgggat ggccgtggaa ctggagtccg
    20041 cggcagactc tttcgcttcg gtgacctcgg ggctggtcgg tggcgcgtgg cagggagcat
    20101 cgtcggtagc gatggggacc gctgcggctt cctacctcgg gtggctgaac gcggcggcgg
    20161 cccatgccga acaggccgcc gcccaggctg aggcgttggt ggccgagttc gccgctgcgc
    20221 agtcagcgat ggtgcagccc ttcctgctcg cggctaaccg ttccagcctg gtgtcgctgg
    20281 tgctgtcgaa cctgttcggc caaaacgcgc cggcgatcgc ggccgtcgaa gccgagtatg
    20341 agcagatgtg ggcgctggat gtgtcaacga tggcgaccta ccatgccggt gcttcagcgg
    20401 cggcagcatc gctgacaccg ctggcacagc ctctacagaa tctgtcggac ctgccgggca
    20461 gggtgatcgc ggcattcgga aatggtgcgc ccgcaaccac ggtcaccgct gcggtcacgg
    20521 cgctgcggct accggcagac gccagcactg tcaacttcgg gctcgccaat atcggtagcg
    20581 gcaacgtcgg taacgcgaac aacggcatcg gcaacctcgg cagcggcaac ctcggcaact
    20641 tcaatctcgg atccggaaat ctcggcagcg ccaatgccgg ctgggcgaac ctgggtagca
    20701 acaacattgg tggcgcaaac agtggtggca ataacctggg ctgggggaac ctgggcggtc
    20761 tcaacactgg gtttgccaac gcgggttccg gcaactttgg atttgccaat accggaaaca
    20821 acaacatcgg catcgggctg accggcgaca atcaggttgg tatcggcggg ttgaactccg
    20881 gcgtcggcaa cttcggcctg ttcaactcgg gcaccggaaa cgtcggcctg ttcaattcag
    20941 gtaccgggaa cttcggcatc ggaaactctg gtgcctacgg caccggactc ttcaactccg
    21001 ggcaggccaa cacgggcttg ctcaatgcgg gatcgttcaa caccggcctg cttgacgtcg
    21061 gcaacgcgaa caccggcagc ctcaacaccg gtagcttcaa catgggttcc ttcaaccccg
    21121 gcccatcgaa cacgggtgcc ctcaacacgg gcaccgccaa cacgggctgg ttcaacacgg
    21181 gcagcctcaa taccggcgca ttcaacatcg gcgacatgaa caacggcctg ttcaacacgg
    21241 gcgagatgaa caacggcatc ttctatcgcg gcgttggcca gggcaatttc tacttctcca
    21301 tcactacgcc cgacctgacc ctgccgcctc ttgaaatccc cggaattacc atccccaatc
    21361 tgagcctgcc gccgattacg gtgcccgcgt tgacgattcc ggcggcgacg acgccggcga
    21421 atgttgtggt gggtgggttt gatttgccgg gggtgacgtt gccggcgttg acgattccgg
    21481 cggcgacgac gccggcgaat gttgtggtgg gtgggtttga tttgccgggg gtgacgttgc
    21541 cggcgttgac gattccggcg gcgacgacgc cggcgaatgt tgtggtgggt gggtttgatt
    21601 tgccgggggt gacgttgccg gcgttgacga ttccggcggc gacgacgccg gcgaatgttg
    21661 tggtgggtgg gtttgatttg ccgggggtga cgttgccggc gttgacgatt ccggcggcga
    21721 cgacgccggc gaatgttgtg gtgggtgggt ttgatttgcc gggggtgacg ttgccggcgt
    21781 tgacgattcc ggcggcgacg acgccggcga atgttgtggt gggtgggttt gatttgccgg
    21841 gggtgacgtt gccggcgttg acgattccgg cggcgacgac gccggcgaat gttgtggtgg
    21901 gtgggtttga tttgccgggg gtgacgttgc cggcgttgac gattccggcg gcgacgacgc
    21961 cggcgaatgt tgtggtgggt gggtttgatt tgccgggggt gacgttgccg gcgttgacga
    22021 ttccggcggc gacgacgccg gccaatgttg tggtgggtgg gttcgatctg ccgcagttgg
    22081 gtattccgtc gttgacgatt ccgcctttga cgttggcgga gggtacgacg gtgggtgcgt
    22141 ttagtctgcc ggagttgggt attccgtcgt tgacgattcc gcctttgacg ttggcggagg
    22201 gtacgacggt gggtgcgttt agtctgccgg agttgggtat tccgtcgttg acgattccgc
    22261 ctttgacgtt ggcggagggt acgacggtgg gtgcgtttag tctgccgcag ctgggcattc
    22321 cgtcgttgac gataccgtcc ttgacggtgc ctgctgggac cacggtcggc ggctttgacc
    22381 ttcctgccct acagacgcga tcgatcaccg tcggtggaat agacgcgggc ggatttagga
    22441 cccccgccat cagcaccgtg tccagcaccg gctacctgga gttgccgacg gtgacaattc
    22501 ctggagtcag ggtgaacaac tttgttgcct tcattcccaa caacatagaa ttcctgcaaa
    22561 cgggtcaacc cggagtgatc ccccaaatcg gtggcttgga gcaccaggca tacatctcta
    22621 cgggcgacat cgtcatccaa ggtttctcga tcagcggcat cggcttctcg cttcccc
//
