LOCUS       NC_010612              23291 bp    DNA     circular CON 17-DEC-2024
DEFINITION  Mycobacterium marinum M, complete sequence.
ACCESSION   NC_010612
VERSION     NC_010612.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium marinum M
  ORGANISM  Mycobacterium marinum M
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
REFERENCE   1  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Davies,J.K.,
            Johnson,P.D., Abdellah,Z., Arrowsmith,C., Chillingworth,T.,
            Churcher,C., Clarke,K., Cronin,A., Davis,P., Goodhead,I.,
            Holroyd,N., Jagels,K., Lord,A., Moule,S., Mungall,K.,
            Norbertczak,H., Quail,M.A., Rabbinowitsch,E., Walker,D., White,B.,
            Whitehead,S., Small,P.L., Brosch,R., Ramakrishnan,L.,
            Fischbach,M.A., Parkhill,J. and Cole,S.T.
  TITLE     Insights from the complete genome sequence of Mycobacterium marinum
            on the evolution of Mycobacterium tuberculosis
  JOURNAL   Genome Res 18 (5), 729-741 (2008)
   PUBMED   18403782
REFERENCE   2  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Pidot,S.J.,
            Davies,J.K., Small,P.L.C., Johnson,P.D.R., Brosch,R., Cole,S.T.,
            Ramakrishnan,L. and Parkhill,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2007) Pathogen Sequencing Unit, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000018345.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,598
            CDSs (total)                      :: 5,546
            Genes (coding)                    :: 5,407
            CDSs (with protein)               :: 5,407
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 53 of 139
            Pseudo Genes (incomplete)         :: 113 of 139
            Pseudo Genes (internal stop)      :: 14 of 139
            Pseudo Genes (multiple problems)  :: 34 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1102417
            Orig. end                         :: 1125708
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000854.1.
            DNA and bacteria are available from Dr Lalita Ramakrishnan,
            lalitar@u.washington.edu.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23291
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="7"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23291
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23291
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13291](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13291)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    269..284
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.61"
                     /tool="antismash"
     misc_feature    472..488
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.11"
                     /tool="antismash"
     misc_feature    complement(653..668)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.86"
                     /tool="antismash"
     gene            772..1632
                     /gene="htpX"
                     /locus_tag="MMAR_RS04480"
                     /old_locus_tag="MMAR_0912"
     CDS             772..1632
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="htpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215077.1"
                     /locus_tag="MMAR_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0912"
                     /product="zinc metalloprotease HtpX"
                     /protein_id="WP_012392834.1"
                     /transl_table=11
                     /translation="MTWHPHANRLKTFLLLVGMSAMIVFFGALFGRTALILAVLFAVGM
                     NVYVYFNSDKLALRAMHAQPVSELQAPAMYRIVRELATSAHQPMPRLYISDTAAPNAFA
                     TGRNPRNAAVCCTTGILALLNERELRAVLGHELSHVYNRDILISCIAGALASVITALAN
                     MAMWAGMFGGNRDGQNPFALLLVSLLGPIAATVVRMAVSRSREYQADESGAVLTGDPLA
                     LASALRKISGGVQLAPLPPEPQLASQAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLE
                     QMARG"
     gene            complement(1653..3254)
                     /locus_tag="MMAR_RS04485"
                     /old_locus_tag="MMAR_0913"
     CDS             complement(1653..3254)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392835.1"
                     /locus_tag="MMAR_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0913"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_012392835.1"
                     /transl_table=11
                     /translation="MPHIEQLDKQGLDHAQHPGTPEPPTTSRLSRVSQISRPDRVRSVI
                     RHDLPASLVVFLVALPLSLGIAIASDAPVLAGLIAAVVGGIIGGALGGSPLQVSGPAAG
                     LTVVVADLIAEFGWGITCFITAVAGLMQILLGFSRVARAALAISPVVVHAMLAGIGITI
                     ALQQTHVLLGGESHSTAWANVVELPAQIVGAHRPGVILGLLVIAIMVAWRWAPAKVAPV
                     PGPLVAIVVVTVVSVVFPFHVSRITLEGSVVDALQLPAIPHGNWGAIVIGIITVTLITS
                     VQSLLTAVATDRMHSGPTTELNRELIGQGASNVVSGAIGGLPIAGVIVRSAANIKAGAK
                     TRASTILHGFWVLLFALPFAGLIEQIPSAALAGLLIVIGIQLLQPAHIETAVKTGDFAI
                     YLVTIVAVVFLNLLHGVMIGLALAIAMTGWRVLRAKVEAHQIDGEWRVVVEGACTFLSL
                     PRLTRVLASVPDSATVTLHIAVNYLDHAAHQAITDWQRRHHATGGKVRIDGALRRGHFA
                     NDGTQLVHDEKSEAAA"
     misc_feature    complement(3314..3331)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            complement(3547..5100)
                     /locus_tag="MMAR_RS04490"
                     /old_locus_tag="MMAR_0914"
     CDS             complement(3547..5100)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392836.1"
                     /locus_tag="MMAR_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0914"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_012392836.1"
                     /transl_table=11
                     /translation="MPSIKRLGKQAQDDGAPVSRTQQLRSVLRYDVPASIVVFLIALPL
                     SVGIAIASGAPVLSGLISAVIGGIVVGLIGGAPLAVSGPANGMMVVTVGLVAQFGWRET
                     CFITVVAGVLQLAFGLIRIARAVLAISPVVVHAMLAGIGITIALQQTHVLLGGESHTTS
                     WENVVELPEQIVEAHKPGVFLGVLVIGIMVAWRWAPAKVAAVPGPLVAIVTATVISLVF
                     PFDLTRITLTGSPLDALQLPALPDGKWSAIAMSVVTVAFIASVESLLAAVSIDRMHPGT
                     PTNFNRELAGQGVANMTSGMVGGLPIAAAIVRSSANVQAGAKSRASTIMHSVWILVFTL
                     FFAGLIQQIPTAALAGMLVFVGIRLLQPAHIETAMRNGDLAVYVVTIVGVVFLNLMQGV
                     LIGLALAIALTAWRVMWFRIHAEPSGDEWHVIVAGTCTFLSVPRLTHVLASIPAGKAVT
                     VTMSVIYLDHAAHQAIADWQQRQLSTGGSVHIHGGVHTGHRARRAMDDLVENAGTETPA
                     "
     CDS             complement(5202..5327)
                     /gene="allorf_1107619_1107744"
                     /locus_tag="allorf_1107619_1107744"
                     /protein_id="allorf_1107619_1107744"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGFLHSWQAGAPGDLCLVCAPHVRLTPVWPLAYCRYDSSAN"
     CDS_motif       complement(5298..5327)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGFLHSWQAG"
                     /locus_tag="allorf_1107619_1107744_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(5202..5297)
                     /prepeptide="core"
                     /locus_tag="allorf_1107619_1107744_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="3334.8"
                     /monoisotopic_mass="3332.6"
                     /core_sequence="APGDLCLVCAPHVRLTPVWPLAYCRYDSSAN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGFLHSWQAG"
                     /leader_location="[5297:5327](-)"
     gene            complement(5333..6358)
                     /locus_tag="MMAR_RS04495"
                     /old_locus_tag="MMAR_0915"
     CDS             complement(5333..6358)
                     /EC_number="1.1.1.94"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215078.1"
                     /locus_tag="MMAR_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0915"
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="WP_012392837.1"
                     /transl_table=11
                     /translation="MAPATREPNVVVLGGGSWGTTVASICARRGPTLQWVRSEATAKDI
                     NDNHRNSRYLGNDVVLSETLRATTDFSEAANCADVVVMGVPSHGFRGVLTELSKELRPW
                     VPVVSLVKGLEQGTNKRMSQIIEEILPGHPAGILAGPNIAREVAEGYAAAAVLAMPDQH
                     LATQLSALFRTRRFRVYTTDDVIGVEMAGALKNVFAIAVGMGYSLGIGENTRALVIARS
                     LREMTKLGVAMGGDTETFPGLAGLGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMN
                     QVAEGVKAASVIMEFANEFGLPMPIAREVDAVINHGSTVEQAYHGLAAEVPGHEVYGAG
                     F"
     gene            6518..8014
                     /locus_tag="MMAR_RS04500"
                     /old_locus_tag="MMAR_0916"
     CDS             6518..8014
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020727483.1"
                     /locus_tag="MMAR_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0916"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_012392838.1"
                     /transl_table=11
                     /translation="MVSRARPARLGSGPVGGRIFALLAVAALLMAGSPGIAYADDGRPQ
                     ANPEERAAALIRPAVMYIVIGAYGWVRLPTGQRLSHYGDNPTKPFTAGWGCTAFTVNPD
                     GWLATAGHCVDPQSARDLIFEHAASDYVKQFPDSPEALNPVGAVQWLRKNARVEGETAE
                     QGPEVSITVLYGSGAKVAATMNADVVDFRPIDKGDVALLRVDRRNMPSSELTTDADVSI
                     GTRILAVGYPKSTQDITDPSLDPTYKSGTVSKKSLRQTIPEYEIDAPISDGMSGGPTIE
                     LNGKVIGLNSFRPASESQPFNFVAPVAGLAALLAAKGVVPTLGPADLSYRKGLDLYYSG
                     HYSAAIKEFDTALSMSPDFPGLVDLRTSAVNLRQQYGDVSVLRGSNLMWYIGLVVVLAV
                     GGGVTFTVLRSRRQRSAASPVPDFQPIPDGWSPVGGGAEGAGEHAADAAAPADAEHLTA
                     GEPHFCANCGAQHHHTEKFCPSCGEPIVIDASAHGKHEKS"
     misc_feature    6545..6547
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8043..9551)
                     /locus_tag="MMAR_RS04505"
                     /old_locus_tag="MMAR_0917"
     CDS             complement(8043..9551)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003873620.1"
                     /locus_tag="MMAR_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0917"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_012392839.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-09, bitscore:
                     36.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 6.4e-07, bitscore: 27.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTPQEAQRTPVERSLLDVVIVGAGISGLGAAYRLLESNPELTY
                     TILERRERIGGTWDLFRYPGVRSDSSIFTLSFPFEPWTRREGVADGEHIREYLANTAHK
                     YGIDGHIQFNSYVRAADWDSGTDSWTVTFEQDGVQRQCRSRFVFFASGYYNYDQGYTPD
                     FPGIEGFTGTVVHPQHWPADLDYTGKKVVVIGSGATAVTLIPSMAEQAAKVTMLQRSPT
                     YLISSSKYSKFAAIARKVLPRKASHLTIRTYNALLEAVLWFLARKLPGFIKWLLRRIAI
                     KNLPAGYDVDTHFKPNYNPWDQRLCLIPDADLYSAVAGGRAEVVTDHIDHFDATGIALE
                     SGRHLDADIIVTATGLQLQALGGVQISLDGTEINPCDRFVYKAHMLEGVPNLFWCVGYT
                     NASWTLRADMTARATAKLLAHMAANGYTHAYPDRGNEAMPEKPSWDIQAGYVLRSLHAL
                     PKSGTKRPWNVRQNYFADAIDYRFDRIDEAMMFGRAADRAPLAG"
     misc_feature    complement(8829..8831)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9718..9733)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(9729..9744)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            9756..9917
                     /locus_tag="MMAR_RS29665"
     CDS             9756..9917
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354531.1"
                     /locus_tag="MMAR_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_015354531.1"
                     /transl_table=11
                     /translation="MMTTLAMELPAVDSILDCRLTDDMIEAAAGMNGLGPCVDQALTAP
                     CLGFARLS"
     CDS_motif       9756..9839
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMTTLAMELPAVDSILDCRLTDDMIEAA"
                     /locus_tag="MMAR_RS29665_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9840..9917
                     /prepeptide="core"
                     /locus_tag="MMAR_RS29665_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.50"
                     /molecular_weight="2426.8"
                     /monoisotopic_mass="2425.2"
                     /core_sequence="AGMNGLGPCVDQALTAPCLGFARLS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMTTLAMELPAVDSILDCRLTDDMIEAA"
                     /leader_location="[9755:9839](+)"
     gene            complement(10001..13291)
                     /locus_tag="MMAR_RS04510"
                     /old_locus_tag="MMAR_0918"
     CDS             complement(10001..13291)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020788647.1"
                     /locus_tag="MMAR_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0918"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_012392840.1"
                     /sec_met_domain="DUF4135 (E-value: 6.9e-94, bitscore:
                     313.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-50, bitscore:
                     169.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDGVGDEWVDGSVAARHDRHALREWLVVHAATIDELLSTRFEAL
                     PGRKADTDAAARRLAAWCRSSASGDWAQFESRLARDGWDFASVLARFANARHTRSLPLP
                     AWVADAMWSRASLCGSPGRATTTGSPEPEPTPPSQFDALLLPLVDEAQARLWSTTDAAA
                     TAILSDSARAGIRRSLLQQLSDLCAPALYALFDSVRELATPDDAHAQPRPDSGVALYQR
                     FVAEMKAAGLSRLLEAKPVLWRLIATITRQWIDTTRELIERLAADLPSIRAGLLAGAPE
                     TRVAGIDGGLSDPHNGGRSVRIVVFENGARVVYKPKDLRVDAALHALVGRLNRAAPPLA
                     LRAVRTIGREGYGWCEFIEHASCADEEGLELYFRRAGAWLALLHCLAATDMHHENFIAH
                     GDYPMPLDIETILQASTQDPDDRDREGRAHQAACNLIADSVMAVGLIPSYRSSGVNGRS
                     AVGGLIANDNTTPTIRWEHVNTDAMRPNKAARPATSMPNLPHVNGHYAKFSDYVDAFIT
                     GFVSYAKFLVRQGADAGAGGLFQEFAGLPVRRVWRPTTFYTMLLQQLTDHRTMHDGVAW
                     SAQADFVARLADWNQDSDPRWPLLQAERSALLSLNVPYFFMASDGVEAHDFAGVSFRCA
                     GMSGLERASARVQDLDDRQIDWQVTVIRHNTETYAGQARSPGTAGPAPQPPQPDGGAWR
                     PAEADFSAEADRIAGELALHAIRRDAGAAWIGLDWSGDSDAAQLVCLGAGLYNGVSGIG
                     LFLAAHAAGSGCQRSAELARAGVAHVCTELTGRNAPRVARSLGISGGSGLGSIAYALAV
                     MAKCLEDDELLAHAHRAALLVTDDLIETDRQLDVVGGSAGAILGLLRVYRDTGSGDVLA
                     RAIRCGEHLLRQPRVGPHGRRTWHRQVPGSCDLNGMAHGAAGYAYALGSLATATGHEEF
                     AQYAAECLAFENASYDRQRGGWPALDVDGGKGWPAQWCHGAPGIGLGRIGLARRGWAQP
                     LSADIANAVTSVRQSWAEQQLDTLCCGALGSIELLSEAATTLDQPDLQGLAARCLSDIV
                     SAATQRGDYRWNSGDQAFNPGLFRGIAGIGYAALRRINRSLPNVLLWE"
     gene            complement(13440..13976)
                     /locus_tag="MMAR_RS04515"
                     /old_locus_tag="MMAR_0919"
     CDS             complement(13440..13976)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392841.1"
                     /locus_tag="MMAR_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0919"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_012392841.1"
                     /transl_table=11
                     /translation="MATADDEILTGPRLILRPLRPTDADVVFFEVTSDDEVMRYLSCNT
                     HSDVEQTRHFITELCMDDNNRGWIINWRSTGDPVGFCTWIRPEGPEVQLGISLGRRWWG
                     QHVTSEALGLLIEQAQRDPSVHRVWAACHVDNIGAARALERNGLSMQDRLERYCVFPNL
                     GAEPQDAFRFARTLR"
     gene            complement(14078..14569)
                     /locus_tag="MMAR_RS04520"
                     /old_locus_tag="MMAR_0920"
     CDS             complement(14078..14569)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_215080.1"
                     /locus_tag="MMAR_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0920"
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="WP_011738960.1"
                     /transl_table=11
                     /translation="MADSSFDIVSKVDHQEVDNALNQAAKELATRFDFRGTDTKIAWKG
                     DEAVELTSSTEERVKAAVDVFKEKLIRRDISMKAFDAGEPQASGKTYKVTGDIKQGISG
                     DDAKKITKLVRDEGPKGVKTQIQGEEIRVTSKKRDDLQTVIAMLKQADLDVALQFVNYR
                     "
     tRNA            14636..14721
                     /anticodon=(pos:1117087..1117089,aa:Tyr,seq:gta)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MMAR_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MMAR_5491"
                     /product="tRNA-Tyr"
     gene            14636..14721
                     /locus_tag="MMAR_RS04525"
                     /old_locus_tag="MMAR_5491"
     gene            complement(14762..17149)
                     /locus_tag="MMAR_RS04530"
                     /old_locus_tag="MMAR_0921"
     CDS             complement(14762..17149)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020727480.1"
                     /locus_tag="MMAR_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0921"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_041324377.1"
                     /transl_table=11
                     /translation="MVTEVPTEPPRARPNWTLLRKTVRDLRRRPAQSVAIAVIVMLGVL
                     LFIASYDSFRNLTASYNRTYDRLHFADLTASGGDPTQLASAARELAGVENVATRVVRDR
                     PVNIDGTKLIGRVVGLTGGGHGVDDVEIVDGRAPDPDAPAQVAIEKHAAESFHLSPGDR
                     VDVYNGSGWRTAEITGVARSPEYLWPARSRQDILPDPHSFAVLFAPPRLAAQLTGQPGP
                     NQTLVQMAAGATTADRDRVAGLLLSRGALDVQTRDEQPSNAALHEDLNGFSELAVGFPV
                     LFLTAAAIAEYVVVTRVVQAERRIMGAMLAMGARPATVIRHYLGYGVAVATMGALLGVV
                     LGAGATSLVTGLYTAAIGVPDTVVRHHVSTAVLGFALGLATGLVAVLVPAITAARTAPA
                     DAMRGQRVLATAMGPLTRLTARWRLPAVIQLAVRSLTRSRGRTVATMVGGVLALILVLA
                     SVGMMTSMRAMLDVQFGEVQRQDASVLVAPSAAGPGGLASQLAALPGVSAVEPSTTVAV
                     TVRAGGRTYATTLTGFVPHSSMHGFRGTDGRTLALSENGVLAGAALADKLDVRVGSDLI
                     VIPAGGSPQHAKLAGLVDEPLGTVLYATNSTVAAITGSVVNGYLLRFGADADRAGLRAD
                     ITSLPGVLAYTDTHALENTVNRYLGLFWAFVGVMLALGGALAFVVIYVTMTVNMAERTT
                     ELATLRAAGVSTPRLTATLTLENLLATAAALPFGLAAGAGAAWLFLQSFNSDLFNMQLA
                     LGWSTLALAAVAVLAAAAISQLPAMRMVRDVDIARVVRERAQ"
     gene            complement(17143..17877)
                     /locus_tag="MMAR_RS04535"
                     /old_locus_tag="MMAR_0922"
     CDS             complement(17143..17877)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011738962.1"
                     /locus_tag="MMAR_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0922"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_012392843.1"
                     /transl_table=11
                     /translation="MTRAQAPTSPRGGVSLHGVDKTFGTAAASVHALRGIDLDIEPGEL
                     VAIVGESGSGKTTLLNVIGGIEEANSGSINVAGQDISGCRPRALSKFRRDHVGFIFQFF
                     NLIPTLTAKENVEVIVELTGRGDRRRATELLDAVGLADRAGSFPGQLSGGQQQRVAIAR
                     ALITDPDLLLADEPMGALDVATGRRVLELLQQTNRSGLGVIMVTHNRAAADVADRIIQM
                     RDGAIVEQRRNSAPAEASSVRW"
     gene            complement(17874..18479)
                     /locus_tag="MMAR_RS04540"
                     /old_locus_tag="MMAR_0923"
     CDS             complement(17874..18479)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020731848.1"
                     /locus_tag="MMAR_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0923"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_012392844.1"
                     /transl_table=11
                     /translation="MPTAAERGAQTRAALMAAAVAVIAERGWGAATTRMVAERAGLPPG
                     LVHYHFASLNDLLIDAALQAAREEAAQVLDGLAGDSPSQGIDRLIDAVSSYDVDDRNQN
                     PAILVFGEMLLAATRYERLRMGLAEILGDYRSALRQWLADQGGAIDPEATAALMFAAID
                     GLVLHRVIDPRLRTLAIRPALRRLAGLPTAQTDERTPP"
     gene            complement(18602..19414)
                     /locus_tag="MMAR_RS04545"
                     /old_locus_tag="MMAR_0924"
     CDS             complement(18602..19414)
                     /NRPS_PKS="Domain: PKS_KR (7-170). E-value: 6.9e-14. Score:
                     44.1. Matches aSDomain:
                     nrpspksdomains_MMAR_RS04545_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020788642.1"
                     /locus_tag="MMAR_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0924"
                     /product="mycofactocin-coupled SDR family oxidoreductase"
                     /protein_id="WP_012392845.1"
                     /transl_table=11
                     /translation="MGALDGRVALITGGARGQGRAHALALAGQGADIALADAPGPMAEL
                     TYPLGSEEDLLATAELVGQLGRRCLPMVVDVRDAAQVNTAVERTVRELGSLDIVLANAG
                     IVSTGRLEEVSDQVWQQLMDTNLTGVFHTLRAAIPVMRQQRFGRIVATSSMGGRMGIPE
                     LAAYNATKWGIIGLIKSVALEVAKEGITANVICPTTTQTPMVQPAGIGDDQEVPDDLVR
                     RMMKANPIPQPWLQPEDVSRGVVYLVTDPGVITGSVLEVGLGGSARMH"
     aSDomain        complement(18905..19393)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS04545_PKS_KR.1"
                     /evalue="6.90E-14"
                     /label="MMAR_RS04545_PKS_KR.1"
                     /locus_tag="MMAR_RS04545"
                     /protein_end="170"
                     /protein_start="7"
                     /score="44.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALITGGARGQGRAHALALAGQGADIALADAPGPMAELTYPLGSE
                     EDLLATAELVGQLGRRCLPMVVDVRDAAQVNTAVERTVRELGSLDIVLANAGIVSTGRL
                     EEVSDQVWQQLMDTNLTGVFHTLRAAIPVMRQQRFGRIVATSSMGGRMGIPELAAYNAT
                     "
     CDS_motif       complement(19322..19387)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MMAR_RS04545_0001"
                     /evalue="2.40E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="MMAR_RS04545"
                     /protein_end="31"
                     /protein_start="9"
                     /score="7.4"
                     /tool="antismash"
                     /translation="LITGGARGQGRAHALALAGQGA"
     gene            complement(19536..20756)
                     /locus_tag="MMAR_RS04550"
                     /old_locus_tag="MMAR_0925"
     CDS             complement(19536..20756)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020731851.1"
                     /locus_tag="MMAR_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0925"
                     /product="sodium:proton antiporter"
                     /protein_id="WP_012392846.1"
                     /transl_table=11
                     /translation="MSLVLAFGVVLLISVSLSGVAARTVLSSALLFLVAGALLGPGILG
                     LDNIGPNDPIVVALADVALFTVLFTDGQRANVRELRETWTLSGRALGVGMPLTMIGIAV
                     PAHFLTGLNWPTAFLVGAILSPTDPVFAAAIVGRSDIPERLRRLLNVESGLNDGLALPF
                     VMIFLATAQGAGSDVLWVGVELVLGLALGVGVAAAVAFAWRAKILTAETHLQPLGPLAI
                     AVVVYSACHLTHANPYLAAFAAGSTLATLDHVAAEQFQPFGDLLSEVTKFAALIVFGAL
                     ITPDRLSGLSWRDWLLAVVVIAVIRPAAMLLSLVRTQLSRQERLTAAWFGPKGFASVVY
                     GLLALQSGLASKELVFDIVAVTIALSIVLHSSTDVPIAKVLQVEPPDDLPGCREPADAD
                     EEATAEV"
     gene            complement(20914..23115)
                     /locus_tag="MMAR_RS04555"
                     /old_locus_tag="MMAR_0926"
     CDS             complement(20914..23115)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1142: PPE family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392847.1"
                     /locus_tag="MMAR_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0926"
                     /product="PPE family protein"
                     /protein_id="WP_012392847.1"
                     /transl_table=11
                     /translation="MIFSVLAPEINSARMYSGAGSGPLLAAAAAWDALAGELGSAVASF
                     GSVTSSLAEGAWQGAASQAMASAAAPYAGWLGLAAARATTAAAQAKVAAGAFEAARAAT
                     VHPALVAINRTRLVSLVTSNLLGLNAPAIAAVEADYEQMWAQDVTAMSGYHGGVSAAAA
                     QLTSWQQALQSLPGLSGFNLGIGNIGTGNIGSGNTGNDNLGGGNNGPSSAGGGNGNVGL
                     GNYGSFNIGAGNGSAALDTAGLQYPGASYHNVGTGNIGIGNIGLGNIGLGNIGFGNGDL
                     ANAVLDGTQSTYNVGGANVGNHNVGLGNVGNNNVGIGNLGNNNIGIGLTGDNQIGIGGL
                     NANGAGWNFGFGNSGSFNLGFGNTGDGNIGLANTGNGNIGIGLTGADQIGFGGWNSGSG
                     NSGLFNSGNDNSGFFNSGSHNWGVANTGSTNWGMVNSGSVNTGIGNTGGTNTGLWNAGT
                     ANTGSLNAGMNNVGLGNSGVADLGAFNSGGNTKHSHDIGIFNAGQHNVGMFNAGSGNLG
                     LSNAGIDNTGAFNSGGNGVSPIFPGAPGQAGNTGFFNSGFTNTGLFNSGNTNTGLWNAG
                     NVNTGFGGIGTYSGNSGFFNSGTGNSGFFNSSDDNSGFGNSSSGGHNSGAANSGSGGYN
                     AGFGNSNTGGGSTGYFNYGDGSLSAGIFNTGTHNAGLLNSGLENIGFFNSGAYDSGWDN
                     SGNSGQVKSLGNSGFGNSGTSSSGGFNAGSGQSGFFNPA"
     misc_feature    complement(23105..23114)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
ORIGIN
        1 cccagcgcca atgcgcgctg gggcaacaac gtcgccatcc tggccggtga ctatctgctg
       61 gcgacggcgt cgcggttggt gtcgcggctg gggccggatg ccgtgcggat cgtcgccgat
      121 acgttcgccc agctggtgac cggtcagatg cgtgagaccc ggggcgcgcc cgagggcgtg
      181 gacatgatcg agcaatacct gaaggtggtt cacgaaaaga ccggctgcct gatcggggcc
      241 gccggccggt tcggtggcat gttttctggc gccgacggcg aacaagtgga gcgactgaac
      301 cgtctcggcg gcatcgtcgg caccgcgttc cagatcgccg acgacatcat cgacatcgac
      361 agcgataccg aacagtcggg gaagctaccg ggcaccgacc tgcgtgaggg ggtgcgcacg
      421 ctgcccatgc tctacgccct gcgccagacc ggctccgacg gcgcccggct gcgcacattg
      481 ctggcgggcc cgatccgcga cgatgccgag gtgttcgagg ccctcgcact gttgcgggcg
      541 tcgccgggta tggaccaggc caaagaggtc ctggggcaat atgccgctcg ggcacgtcac
      601 gagttggatt tgctgcccga cgtcccgggc cgccaggcgc tggccgcgtt ggtcgactac
      661 acggtcaacc ggcacgggta gagcgcggcg tttcggaacc ccgagggccg tttcgggcgt
      721 taaatcagct gtaataacca agttgccgtg ttcgtgggag gacacacacc gatgacctgg
      781 catccgcatg ccaacaggct gaagactttc ctgctgctgg tcggcatgtc cgccatgatc
      841 gtgttctttg gtgcgctgtt cggcaggacg gccctgatcc tggcggtgct gttcgccgtc
      901 gggatgaacg tctatgtcta cttcaacagc gacaagctgg ccctgcgggc catgcatgcg
      961 cagccggttt cggagctgca ggctccggcc atgtaccgga tagtgcgtga gctggccacc
     1021 agcgcccacc agccgatgcc gcggctgtac atcagtgaca ccgccgcacc caacgccttc
     1081 gccaccgggc gcaacccgcg caacgccgcg gtgtgctgca ccacgggcat cctggcgctg
     1141 ctcaacgagc gggaattgcg tgccgtgctg ggccacgagc tgtcacacgt ctacaaccgc
     1201 gacatcctga tttcctgtat cgccggagcg ctggcgtcgg tgatcaccgc gctggccaac
     1261 atggccatgt gggccggcat gttcggtggt aaccgagacg gccagaaccc gttcgccctg
     1321 ctgctggttt cgttgctggg cccgatcgcg gcgacggtgg tgcggatggc ggtgtcgcgt
     1381 tcgcgcgaat atcaggccga cgaatcgggt gcggtcttga ccggtgaccc gttggcgttg
     1441 gcgtcggcac tgcgcaagat ctccggtggc gtgcaactgg ctccactgcc gcccgagccg
     1501 cagctggcca gccaggcgca cttgatgatc gccaatccgt tccgtgccgg tgagcggatc
     1561 ggatcgctgt tctcgacgca tccgccgatc gaggaccgga tccggcgttt ggagcaaatg
     1621 gcccgcggat agcggggttc ggccggccgc cgtcaggcgg cggcttcgga cttttcgtcg
     1681 tggaccaact gtgtgccgtc gttggcgaaa tgacctctgc gcagggcgcc atcgatgcga
     1741 accttcccgc cggtggcgtg atggcgtcgc tgccagtcgg tgatcgcctg gtgcgcggcg
     1801 tggtcgaggt agttgaccgc gatatgaaga gtgaccgtcg cgctgtcagg caccgaggcc
     1861 agcacccggg tcagtcgggg tagggacagg aaggtgcagg cgccctcgac gaccacccgc
     1921 cattcgccgt cgatttggtg tgcttcgacc ttggcccgca gcactcgcca ccccgtcatc
     1981 gcgatggcca gggccagccc gatcatcacg ccgtgcagca gattcaggaa gaccaccgcg
     2041 acaatcgtca ccaggtagat ggcgaagtcg ccggtcttga ccgcggtttc gatgtgtgcg
     2101 ggctgcagta gctgaatacc gatgacgatc agcagtcccg cgagcgcagc gctggggatt
     2161 tgttcgatca aacccgcaaa ggggagtgcg aacagcagga cccagaaacc gtgcaggatt
     2221 gtcgacgccc gagttttggc acccgccttg atgtttgccg cgctgcggac gatgacaccg
     2281 gcgatgggga ggccgccgat tgcccccgac acgacgttgg atgcgccctg gccgatcaat
     2341 tcacggttga gttcggtggt tgggccgctg tgcattctgt cggttgccac cgctgtcaac
     2401 aggctctgga cgctggtgat gagcgtcacg gtgatgatgc cgatcacgat ggcgccccag
     2461 tttccgtgcg gaattgcggg cagctgcagt gcatccacga ccgagccctc gagagtgatg
     2521 cgggacacat ggaacggaaa caccaccgag acaacggtta ccaccacgat ggcgaccagc
     2581 gggccgggaa cgggagccac cttggccgga gcccagcgcc aagcgaccat gatcgcgatg
     2641 accagcagcc ccaggatcac tccgggccgg tgcgcgccga caatctgtgc gggcagctcg
     2701 accacgttgg cccaggccgt gctatgtgat tcgccaccga gcaacacgtg cgtctgttgc
     2761 agcgcgatgg tgatcccgat accggccagc atggcgtgca ccaccactgg cgagatcgca
     2821 agggcggctc gcgcgacccg gctgaacccc aataggatct gcatcagccc ggcgaccgcc
     2881 gtgatgaaac aagtgattcc ccatccgaat tcggcgatga ggtcggcgac cacgaccgtc
     2941 aggccggcgg cgggcccgct gacctgcagc ggagatcccc ccagtgcgcc accgatgatc
     3001 ccgcccacca cggccgcgat caacccggcg agcaccggag catccgaggc aatggcgatg
     3061 cccaatgaca acggcagtgc taccaggaaa acaaccagcg aggctggcaa gtcgtgcctg
     3121 atgactgatc gcacccggtc ggggcgcgat atctgcgata cccgcgacaa ccgcgatgtt
     3181 gttgggggtt ccggggtgcc cgggtgctgg gcgtgatcaa gaccttgttt atcgagctgt
     3241 tcgatgtgtg gcatcggccg atcccctcgt tgggccttag cgggggatgt tgcgatatcc
     3301 cgccccacgt gctgtaacgg actcgtaacg tgttcgcgca ctagcaaata cgaatggccg
     3361 aactccgccg aacttcattg tgtcagtctg ctatgcgtcc gatcatccga ggctattgag
     3421 cgggccaagc gacggcaacc tggttcgccc gctgcatagc gaatgcaaat gttcagcgtg
     3481 accaggcgcg caagtccaag tgtgatgcga accagaccgg ccggcgatgg tccggcgaat
     3541 ccttcgctaa gcgggagtct cagtgcctgc attctcgacc aggtcgtcca tcgcccggcg
     3601 agcgcggtgt ccggtatgga cgccaccgtg gatgtgaacc gacccgccag tcgaaagttg
     3661 tcgctgctgc cagtcggcaa tcgcttgatg cgcggcatga tcgaggtaga tgaccgacat
     3721 cgtcacggta accgctttgc ccgcggggat ggacgcgagt acgtgggtca gccggggcac
     3781 ggacaggaag gtgcatgtcc cagcgacgat cacgtgccat tcgtcgcccg agggctcggc
     3841 gtggatcctg aaccacatca cccgccacgc ggtcagcgcg atggccaagg cgagtccgat
     3901 cagcacgccc tgcatgagat tgaggaacac gacgccgacg atggtcacca catagacggc
     3961 cagatcacca ttgcgcatgg cggtttcgat atgggcaggc tgcagcagcc tgatgccgac
     4021 gaaaaccagc atgccggcaa gtgcggcggt ggggatctgt tggatcaacc ccgcaaaaaa
     4081 cagcgtgaag acgaggatcc acacactgtg catgattgtc gaggcgcggc tcttggcgcc
     4141 cgcctggaca ttggccgaac tacggacgat tgcggcggcg atggggagac caccgaccat
     4201 accggatgtc atgtttgcca caccttgtcc ggccagttcg cggttgaagt tggtgggtgt
     4261 gccggggtgc attctgtcga tcgacacggc tgccagcaag ctctcgacgc tggcaatgaa
     4321 agcgacggtg accacgctca tcgcgatagc gctccacttg ccatcgggta gggccggcag
     4381 ctgcaacgca tccaggggcg atcccgtgag cgtgatccgg gtcaggtcga acgggaacac
     4441 caacgagatg acggttgcgg tcacgatggc caccagcggc cccggaacgg cagccacttt
     4501 ggccggggcc cagcgccacg cgaccatgat gccgattacc aacacgccca ggaacactcc
     4561 cggtttatgc gcctcgacga tttgttcggg tagctcaaca acgttttccc aggatgtggt
     4621 gtgggactcc ccgcccagca acacgtgcgt ttgctgaagt gcgatcgtga ttccgatgcc
     4681 ggccagcatc gcgtgtacga cgacaggcga gatcgccagt accgctcgcg caatgcggat
     4741 gagtccgaaa gcgagctgca ggacacctgc gacgaccgtg atgaaacacg tttcccgcca
     4801 accaaattgg gcgacgaggc cgaccgtgac caccatcatc ccattcgcgg gaccgctgac
     4861 cgccagtggt gctccgccga tgagtccaac cacgatcccc ccgatcaccg ccgagatcag
     4921 gccggagagc accggtgcgc ccgaagcgat ggcgattccc accgatagcg gtagcgcgat
     4981 cagaaaaacc acaatcgacg cgggcacgtc gtaccggagg accgagcgca gttgctgagt
     5041 tcgcgacacc ggcgcgccgt cgtcttgggc ttgcttgcca agtcgtttga tggacggcat
     5101 caatcattcc ctcgtcggtc agtgcggggg acggttggac agtcagctcc gtatcacccg
     5161 ggtcacccac ccgtagggcc tccgacgaaa cgggagcgtc gttagttggc actgctgtcg
     5221 tatcgacagt atgcaagcgg ccaaaccggg gtcaacctca catgcggcgc gcataccaaa
     5281 cacagatctc ccggcgcacc ggcttgccag ctgtgcagaa accccaaccg ggctagaacc
     5341 cggccccgta cacctcatgg ccgggtactt cggcggccag cccgtggtag gcctgttcga
     5401 cggtcgatcc gtgattgatc acggcgtcga cctcgcgggc gatcggcatg ggcagcccga
     5461 actcattggc gaattccatg atgacgctgg ccgccttgac cccctcagcg acctggttca
     5521 tcgaggcgat gatctcatcg atgggtttgc cggcgcccaa ttgttcacca acgtggcggt
     5581 tgcggctgcg ctggctggtg caggtgacga tgaggtcacc caggccggcc agtccgggga
     5641 aggtttcggt gtcaccgccc atcgccacac cgagcttggt catctcgcgc agtgagcggg
     5701 cgatgaccag ggcgcgggtg ttctcgccga tgcccagcga gtagcccatg ccgacggcga
     5761 tggcgaacac gttcttgagc gcacccgcca tctcgactcc gatgacgtca tcggtggtgt
     5821 agacgcggaa ccgtcgggtg cgaaacagcg cggacagttg ggtggccaga tgctggtcgg
     5881 gcatggccag caccgcggcg gccgcgtacc cttcggccac ctcgcgtgcg atgttcggcc
     5941 cggccaggat gcctgccgga tggccgggca agatctcctc gataatctgc gacatccgct
     6001 tgttggtgcc ctgttcgagc cctttgacca gcgataccac cggcacccac gggcgcagtt
     6061 ccttgctcag ctcggtcagt acaccccgga agccgtgcga gggcacgccc atgacgacga
     6121 cgtcggcaca gttggcggcc tcggagaagt cggtggtcgc gcgcagcgtt tcgctgagca
     6181 cgacgtcgtt tccgaggtag cggctgttgc ggtggttgtc gttgatgtcc tttgcggtcg
     6241 cttccgaacg cacccattgc agcgtcggcc cacgccgtgc gcagatcgat gcaaccgtgg
     6301 ttccccagga accgccaccg aggacaacga cgttgggttc gcgcgtagca ggtgccatgg
     6361 cacccagcgt attgccgagg ctcgacattg agaagcagcc agtgtcaggt cgccaaagtc
     6421 gaaaccaatg accacccagc atgggacttc ggtccctacc gtctgacacc gtcgaggccc
     6481 gatggtggag atcaacggat gcctaccagg aggagtcatg gtcagccgcg cgcgcccggc
     6541 aaggttaggg tccgggcctg ttggcggccg gatatttgcg ctgctggcgg tggccgcgct
     6601 gctcatggcc ggctcgccgg gcatcgcgta cgccgatgac ggtcggccac aggccaaccc
     6661 ggaggaaagg gctgcggcgc tgatccggcc ggcggtcatg tacatcgtga tcggagccta
     6721 tggctgggtg cggctgccca ccggccagcg gctctcccac tacggcgaca acccgaccaa
     6781 gccgttcacc gcgggctggg gttgcaccgc gttcaccgtg aaccccgacg gctggctggc
     6841 gaccgccggg cactgcgttg atccgcaaag cgccagggac ctgattttcg agcatgcggc
     6901 gagcgactac gtgaagcaat tcccggactc gcccgaggcg ctgaatccgg ttggcgcggt
     6961 gcagtggctt cgcaagaacg ccagggtcga gggtgaaacc gccgagcagg ggccagaagt
     7021 cagcatcacg gtgttgtacg gaagcggggc aaaggtggcc gcgacgatga acgccgacgt
     7081 cgtggacttc cggccgatcg acaagggtga cgtcgcgctg ctgcgggtgg accggcgcaa
     7141 catgccctcc tcggagctga ccaccgacgc cgacgtcagc atcggcaccc ggattctggc
     7201 ggtgggatat ccgaagagca cccaggacat caccgatccc tcgcttgacc ccacctacaa
     7261 gagcggcacg gtcagcaaga aatcacttcg ccagaccatt cccgaatacg agatcgatgc
     7321 gccgatctcg gacggcatga gcggcgggcc gaccatcgaa ctcaacggca aggtgatcgg
     7381 gctgaacagc ttccgcccgg ccagcgaatc gcagccgttc aactttgtcg cgccggtggc
     7441 cggcctggcc gcattgctgg ccgccaaggg ggtcgtgccc accctgggcc cggccgatct
     7501 gtcctatcga aaggggctcg acctgtacta ctcgggccac tacagcgcgg cgatcaaaga
     7561 attcgacacg gcgttgtcga tgtcaccgga ttttcccggg ttggtcgatc tgcgcaccag
     7621 cgctgtcaac ctgcgtcagc agtacggcga cgtttcggtg ctacgtggct cgaatctgat
     7681 gtggtacatc ggccttgtcg tggtgctggc ggtcggcggt ggcgtgacct tcacggtgtt
     7741 gagaagtcgc cggcagcgct cggcggcctc tccggtgccc gactttcagc cgattccgga
     7801 tgggtggtcg ccggttggcg gcggggccga aggtgccggt gagcacgcgg ccgatgccgc
     7861 ggctcccgcg gacgcggagc atctgacggc cggtgaaccc cacttctgtg cgaactgcgg
     7921 ggcgcagcat catcacaccg aaaagttctg ccccagctgc ggtgagccga tcgtcattga
     7981 cgcatccgcg cacggaaagc acgagaagtc ctgacgccgc cgcgactatc ggctaccggt
     8041 gttcagcccg ccaggggcgc gcggtcggcg gcgcggccga acatcatggc ctcgtcgatg
     8101 cggtcgaacc ggtagtcgat ggcgtcggcg aaatagtttt gccgcacgtt ccagggccgc
     8161 ttggtccccg atttgggcag tgcgtgcagc gaccgcaaca catagccggc ctgaatgtcc
     8221 caggacggtt tttccggcat cgcctcgttg ccccggtccg ggtaggcgtg cgtatagccg
     8281 ttggcggcca tgtgcgccag caacttcgcc gtggcccgcg cggtcatgtc ggcgcgcagc
     8341 gtccacgatg cattggtgta gcccacacac cagaacaggt tgggcacccc ttcgagcatg
     8401 tgcgctttgt agacgaacct gtcacagggg ttgatctcgg tgccgtccag actgatctgc
     8461 accccgccaa gtgcctgcaa ctgcaggccg gtggcggtga cgatgatgtc ggcatcaaga
     8521 tgtcggccgg actcgagtgc gatgccggtg gcgtcgaaat ggtcgatgtg gtcggtgacc
     8581 acttcggcgc gcccgccggc cacggcgctg tacagatcgg catcggggat caggcacagg
     8641 cgctgatccc acgggttgta gttcggcttg aagtgggtgt cgacgtcata gccggcgggc
     8701 aggttcttga tcgcaatgcg ccgcagcagc catttgatga agcccggcag cttgcgggcc
     8761 aagaaccaga gcaccgcttc cagcagggcg ttgtatgttc ggatcgtcaa atgagatgcc
     8821 ttgcggggta atactttacg tgcgatggca gcaaatttgc tgtacttgga agacgagatg
     8881 aggtaggtcg gcgagcgctg cagcatggtc accttggcgg cctgctccgc cattgacggg
     8941 atcagcgtga ccgcggtagc gccgctgccg atcaccacga ccttcttgcc ggtgtaatcc
     9001 aggtcggccg gccagtgctg tgggtgcacc acggtgccgg tgaacccctc gatgccgggg
     9061 aaatcgggcg tgtagccctg gtcgtagttg tagtagccgc tggcgaagaa cacgaaccgg
     9121 ctgcggcatt gcctctgcac gccgtcctgc tcgaaggtga ccgtccagct gtcggtgccc
     9181 gaatcccagt cggccgcccg gacatagctg ttgaactgga tatggccgtc gatgccgtac
     9241 ttgtgagcgg tgttggccag gtactcccgg atgtgctcgc cgtcggccac gccctccctg
     9301 cgggtccatg gttcgaacgg aaagctcaac gtgaagatgc tgctgtcgga gcgcacgccc
     9361 ggatagcgaa acaggtccca ggtgccgccg attcgctcac ggcgttccag gatggtgtag
     9421 gtcagttcgg ggttgctctc gagcagccgg taggccgctc cgaggccgga gatgccggcg
     9481 ccgacgatga cgacgtcgag caagctccgc tcgaccggag tgcgttgggc ttcttggggg
     9541 gtcacgctca tcgtggacct cgcttgtttc tgggttgcgt catcagagta gacacccacc
     9601 ggttggtcga gccagggcag ttcggcacta gtgctgcggc ggttgttgga cggtgaaccg
     9661 gcgccgagcg tggcatccgg ccagggcgcc gcggtttgac gcattgcgca accagacttg
     9721 acaaaaacgt ttagatcggg aaacaatgcg aaaccatgat gaccactctt gccatggaac
     9781 tgccggctgt tgacagcatc ctcgactgcc gcctcaccga cgacatgatc gaggccgccg
     9841 cgggaatgaa cggcctgggg ccttgtgtgg atcaagcttt gaccgctccc tgcctgggtt
     9901 ttgcacgcct ctcctgagag ttcgggcgct ctggtagcga tcgcctgaat tttgttgagg
     9961 gccttgatga atggcccgtc tcaatcccgg ttgccggtgt ctattcccag agcagcacat
    10021 tgggcaggga ccggttgatg cgacgcaggg cggcatagcc tatgccggcg attccgcgaa
    10081 acaatccggg gttgaatgct tgatcgccgc tgttccatcg atagtcgccg cgttgggtcg
    10141 ccgcggacac gatgtcgctc aggcatcgtg ccgcaagacc ctgaagatca ggctggtcca
    10201 acgtcgtcgc ggcttcgctg agcaattcga tgctgcccag agcaccacaa caaagcgtgt
    10261 ccaattgttg ctcagcccag ctttgacgga ccgaagtcac ggcgttggca atatcggccg
    10321 acagtggctg cgcccagccg cgtcgtgcca agccgatgcg ccccaaaccg attccgggtg
    10381 cgccgtggca ccactgcgcg ggccagcctt tccccccgtc cacatccagt gcgggccagc
    10441 cgccgcgctg ccggtcgtag ctggcgtttt caaaggccag gcactccgcc gcgtattgtg
    10501 cgaactcctc gtgaccggtt gctgtggcca atgaccccag ggcgtacgca tagcccgctg
    10561 caccgtgcgc catgccgttc agatcgcaag agccgggcac ctgtcggtgc caggtgcgcc
    10621 ttccgtgcgg gccgacgcgg ggttggcgca acaggtgctc gccacaccga atcgcacgcg
    10681 cgagcacgtc gccggagccg gtgtctcgat agacccggag cagcccaagg atcgcgccgg
    10741 cgctaccccc gacgacatcg agttgccggt cggtctcgat cagatcgtcg gtgaccagca
    10801 gcgccgccct atgcgcgtgg gcgagcaatt cgtcgtcctc gaggcacttc gccatgaccg
    10861 ccaatgcgta ggcgatcgac cccaaaccgg agccgccgct gattcccagc gagcgggcca
    10921 cgcgtggcgc gttgcggccg gtcagttcgg tgcacacgtg tgcgaccccg gcccgggcca
    10981 gctcggccga ccgctggcag cccgagccgg ccgcgtgcgc ggccaagaag aggccgatgc
    11041 cggacacgcc gttatagagg ccggcgccca ggcagacgag ctgggcggca tccgaatcgc
    11101 ctgaccagtc caacccgatc caggcggcgc ccgcatctcg gcgaatcgcg tgaagagcca
    11161 gttccccggc gattctgtcg gcctcggcgg aaaagtccgc ttcggccggt cgccaggcgc
    11221 caccgtcggg ctggggcggc tgcggtgctg gacccgctgt gcccggtgac cgcgcttgtc
    11281 ccgcataggt ttccgtattg tgccggatga ccgtgacttg ccagtcgatc tgtcgatcat
    11341 cgaggtcttg aacgcgcgca gacgcgcgtt ccaggcctga catgcccgcg caccggaacg
    11401 agactccagc gaaatcatgg gcttcgacac cgtcgctggc cataaaaaag taggggacgt
    11461 tcaacgacaa cagggccgat ctctccgcct gtaggagcgg ccaacgcgga tcgctgtctt
    11521 ggttccaatc agccagtctg gcaacgaagt ccgcttgcgc cgaccaagca acaccatcat
    11581 gcatggtgcg atgatcggtg agctgctgca gcagcatggt gtagaaggtg gtcgggcgcc
    11641 acaccctgcg caccggcaag ccggcaaact cctggaacaa accgccggcc ccggcatcgg
    11701 cgccttgtcg aaccaggaac ttggcgtagg acacgaaacc ggtaatgaag gcgtcgacgt
    11761 agtcgctgaa cttggcgtag tgcccgttga cgtggggtag gttcggcatg ctcgtggcgg
    11821 gccgcgccgc tttgttcggc cgcatcgcgt cagtgttgac gtgctcccaa cggatcgtcg
    11881 gcgtggtgtt gtcgttcgcg atcaacccac cgaccgcgga acgcccgttg acgccggagc
    11941 tccgatagga cgggatcaag cccaccgcca tcaccgaatc ggcgatgagg ttgcatgcgg
    12001 cttggtgggc acggccttcc cgatcacggt cgtcggggtc ctgcgtgctc gcctgcagga
    12061 tcgtctcgat gtccagcggc atcgggtagt cgccgtgtgc gatgaagttt tcgtggtgca
    12121 tgtcggtggc ggccaggcag tgcagcagtg ccagccaggc gccggcgcgc cggaagtaca
    12181 actcgaggcc ttcttcgtcc gcgcacgatg catgctcgat gaactcgcac cagccgtagc
    12241 cttcgcgtcc gatcgtgcgg accgcacgca acgccagcgg gggagcggcc cggttgagcc
    12301 tgccgaccag ggcgtgcagg gcggcatcca cccgcaagtc cttcggcttg tagaccaccc
    12361 gcgcgccgtt ctcgaacacg acgatccgta ccgagcggcc gccattgtgt ggatcggaga
    12421 gcccgccatc gattccggcc accctcgttt cgggggcgcc cgcgagcagg ccagcgcgga
    12481 tggacggcag atccgcggcc agacgttcga tcagttcgcg cgtggtgtca atccattggc
    12541 gggtgatcgt ggcgatcagc cgccacagca ccggtttggc ttccagcagc cgggacaggc
    12601 ccgccgcttt catctctgcg acaaaccgct gatagagcgc gactcccgag tccggtctgg
    12661 gctgcgcgtg agcatcgtct ggggtcgcga gctcgcgcac cgagtcaaag agcgcataca
    12721 gcgccggcgc gcacaggtcg gacagttgtt gcaacaacga tcgccgaatg cctgcgcgtg
    12781 ccgaatcgct cagtatcgcc gtggcggcgg cgtccgtggt cgaccagagt cgggcctgcg
    12841 cctcgtcgac cagtggcaac agcagggcgt cgaattggct ggggggcgtg ggctcgggct
    12901 cgggcgaacc ggtggtggtg gctcggccgg gtgagccgca caacgacgct cgggaccaca
    12961 tcgcgtcagc cacccacgcc ggcagcggca aggaccgagt gtgccgggca ttggcgaaac
    13021 gcgccagcac gcttgcgaag tcccaaccgt cgcgagccaa tcgcgactcg aactgcgccc
    13081 agtcaccgct tgcgctggaa cgacaccacg cggcaagtcg gcgcgcggcg gcatcggtgt
    13141 cggccttccg gccgggcagc gcctcgaaac gcgtagacaa cagttcatcg atcgttgcgg
    13201 catggacaac cagccactcg cgcagcgcat ggcgatcatg tcgcgcggct accgagccgt
    13261 cgacccactc atccccgaca ccgtcaccca tcgcccatct gtccaaccat cggacccgcg
    13321 cccggcattc gcagtaccca agctacgact tcgctgcccg tggtaatgcc gaatcgcgca
    13381 acctgttgcg ggcaagccgc tttcgcgcgg tggccaaggc ttgcgatgcg gcgatgaagc
    13441 tatctgagcg tccttgcgaa ccgaaaggcg tcctgcggct ccgcgccgag gttggggaac
    13501 acgcagtagc gctccagccg gtcctgcatg gacaaaccgt tgcgctccag cgctcgtgcg
    13561 gctccgatgt tgtcaacgtg gcatgcggcc cacacgcgat gcacgctcgg atcccgctgt
    13621 gcctgttcga tgagcaagcc cagcgcctcg gacgtgacat gttgccccca ccaacggcgg
    13681 ccgagggaga tgcccagttg aacctcgggg ccctccggcc ggatccaggt gcagaacccg
    13741 accggatcgc cggtgctgcg ccagttgatg atccaaccgc gattgttgtc gtccatgcac
    13801 agctcggtga tgaagtgcct ggtctgctcg acgtcggaat gcgtgttgca cgaaaggtag
    13861 cgcatcactt cgtcatccga ggtgacctcg aagaacacga catcggcgtc ggtgggccgc
    13921 agggggcgca ggatcagccg cgggccggtg aggatttcat cgtcggcagt cgccataggg
    13981 gccccctaat gcggaccttc atagcctacg tggccagcgt gtccagcact tctacgaccc
    14041 ggacgaccat gatcgcttcg ggcgcccgca gggagttcta tcggtagttg acgaactgca
    14101 gcgcgacgtc caggtcggcc tgcttgagca tggcgatgac ggtctgtagg tcgtcgcgct
    14161 tcttgctggt gacgcgaatc tcctcgccct ggatctgggt cttgacgccc ttggggccct
    14221 cgtcgcggac gagcttggtg atcttcttgg cgtcgtcacc gctgatgccc tgcttgatgt
    14281 cgccggtgac cttgtaggtc ttgccggatg cctggggctc gccggcgtca aaggccttca
    14341 tcgagatgtc gcggcggatg agcttttcct tgaagacgtc caccgcggcc ttgacccgct
    14401 cctcggtgga cgaggtcagt tccactgctt cgtcgccctt ccacgcgatc ttggtgtcgg
    14461 tgccgcggaa gtcgaatcgc gtggccagct ccttggcggc ctggttgagc gcgttgtcga
    14521 cttcctggtg gtcgaccttg ctgacgatgt cgaacgatga gtcggccatg cgataagtcc
    14581 cttctttgga gagccgtttg tgctctgtct acccggtcgt tgtaccctgc tatgcggcag
    14641 gttgcccgag cggccaatgg gagcggactg taaatccgtc ggcttacgcc tacacaggtt
    14701 cgaatcctgt acctgccacc aacttgagca ctgcgcgcgt gcccgctgac cccggtggat
    14761 gttattgggc ccgttcgcgc accacgcgcg cgatgtcgac atcgcgcacc atccgcatcg
    14821 cgggtagctg cgaaatcgcg gcggcggcga gcacggcgac cgccgccagc gccaacgtcg
    14881 accacccgag ggccagctgc atgttgaaca gatcactgtt gaaggactgc aggaacagcc
    14941 acgccgcccc cgcgcccgcg gccagcccga agggaagtgc tgccgcggtg gcaagcaggt
    15001 tctccagggt cagcgtcgcg gtgagccgcg gtgttgacac gccggccgcg cgtagggtgg
    15061 ccaactccgt ggtgcgttcg gccatgttca ccgtcatcgt tacgtagatc accacgaagg
    15121 ccagtgcccc gcccagcgcc agcatgaccc cgacgaacgc ccaaaacaac ccgaggtagc
    15181 ggttgaccgt gttctcgagt gcgtgggtgt cggtgtaggc gagcacaccg ggcagcgagg
    15241 tgatgtccgc gcgcaacccg gcgcggtcgg catcggcgcc gaagcgcaac aggtacccgt
    15301 tgaccacgct gccggtgatc gcggcaaccg tcgagttggt ggcatagagc accgttccca
    15361 gcggttcgtc gaccaggccg gccaacttgg catgctgtgg cgatcccccc gcggggatga
    15421 cgatcagatc ggagccgacc cgcacgtcga gtttgtcggc cagtgctgcc ccggccagca
    15481 caccgttttc ggacagggcc agcgtgcgcc cgtcggtgcc ccggaatccg tgcatggagc
    15541 tgtgtggcac gaaaccggtc agcgtcgtcg cataggtgcg tccgccggcg cgtacggtca
    15601 ccgcgacggt ggtgctgggt tcgaccgccg acaccccggg tagggccgcc aattggctcg
    15661 ccaagccgcc ggggcccgcc gcgctgggcg caacgagcac cgaagcgtcc tgccgttgca
    15721 cctcaccgaa ctggacgtcg agcatggcgc gcatgctggt catcatcccg accgaggcca
    15781 acaccaggat caacgccagc accccgccca ccatggtcgc gacggtgcgc ccgcggctgc
    15841 gggtcaacga ccgcacggcg agttggatca ccgcgggcag ccgccaccgc gcggtcagcc
    15901 gggtaagtgg ccccatcgcg gtggcgagca ctcgttggcc gcgcatggcg tcagccggcg
    15961 cggtgcgtgc cgcggtgatg gccggcacca gcacggcgac caggccggtt gccaggccga
    16021 gggcgaagcc caggaccgcg gtggacacgt ggtgtcggac caccgtgtcg gggaccccga
    16081 tggccgcggt gtacaggccg gtgaccagcg aggtggcgcc cgcaccgaga acgacgccga
    16141 gcagcgcgcc catggtggcc accgcgacgc cgtatcccag gtagtgccgg atgaccgtgg
    16201 ccggccgggc gcccatggcc agcatcgcgc ccatgatccg ccgctcggcc tgcacgaccc
    16261 tggtgacgac gacgtactcg gcgatcgcgg cggcggtcag gaagagcacc gggaatccca
    16321 ccgcgagttc ggagaagcca ttgaggtctt cgtgcagcgc tgcgttggaa ggttgctcgt
    16381 cgcgggtctg cacgtccaag gcgccgcggg acagcagtag cccggccacc cggtcccgat
    16441 cggccgtggt cgctccggcg gccatctgga ccagggtctg attgggccct ggctgcccgg
    16501 tgagctgtgc ggcgagccgc ggtggcgcga acagtacggc gaaggaatgt gggtcgggca
    16561 ggatgtcttg acgactacgc gccggccaca agtactcggg cgagcgggcc accccggtga
    16621 tctcggcggt gcgccaaccg gagccgttgt agacatcgac gcgatcgccc gggctcaggt
    16681 gaaatgactc ggctgcgtgt ttttcgatcg cgacctgtgc gggggcatcg ggatcgggtg
    16741 cgcgtccgtc gacgatctcc acgtcgtcga ccccgtggcc gccgccggtc aacccgacca
    16801 cccgaccgat cagtttggtg ccgtcgatgt tcaccggtcg gtcccgcacc acgcgggtcg
    16861 cgacgttctc gacgccggcg agctcccgcg cggcggaggc cagctgggtg gggtcgcctc
    16921 cggaggcggt gaggtcggcg aaatgcagcc ggtcataggt gcggttgtag gacgccgtga
    16981 ggttgcggaa cgagtcataa ctggcgatga agagcagcac cccgagcatc acgatgaccg
    17041 cgatggccac cgattgagcg gggcgtcgcc gcagatcacg gacggtcttg cggagcaggg
    17101 tccagttcgg ccgggcgcgg ggcggttcgg ttggcacctc agtcaccacc gcacgctgct
    17161 tgcctcggcc ggtgctgagt tgcgacgctg ctcgacgatc gctccgtcgc gcatctgaat
    17221 gatgcggtcg gcgacatcgg cggccgcccg gttgtgggtc accatgatga cgcccagacc
    17281 cgaccggttg gtctgctgca gcagttcgag cacgcgtcgg ccggtggcca cgtcgagcgc
    17341 ccccatcggc tcgtcggcca gcagcaggtc cgggtcggtg atcagcgcac gcgcgatggc
    17401 cacccgctgt tgctggccgc cggagagctg gccggggaaa ctgccggccc gatcggccag
    17461 cccgaccgca tccagcaatt cggtcgcgcg gcgccgatca cctcggccgg tcagctcgac
    17521 gatcacttcg acgttttcct tggcggtcag cgtcgggatc agattgaaga actggaagat
    17581 gaaccccacg tggtcgcggc ggaacttgct cagtgcgcgc ggccggcacc ccgaaatatc
    17641 ttgtccggca acgttaatag aaccgctgtt ggcctcctcg atgccgccga tgacgttgag
    17701 cagggtggtc ttgcccgacc cgctttcccc gacgatcgcc accagttcac cgggttcgat
    17761 gtccaggtcg atgccgcgca gcgcatgtac cgacgctgct gcggttccga aggtcttgtc
    17821 gacgccgtgc agagaaaccc caccgcgcgg tgaggtaggc gcttgcgctc gtgtcatggt
    17881 ggcgtcctct cgtcggtctg ggccgtcggc agtcccgcca gccggcgcaa cgccggccgg
    17941 atggccaggg tgcgcaatcg cgggtcgatc acccggtgca gcaccaatcc gtcgatggcc
    18001 gcgaacatca atgccgcggt cgcctcggga tcgatggcgc cgccctgatc tgcgagccac
    18061 tgacgcaggg cggatcggta gtcgccgagg atttccgcca agcccattcg cagccgctcg
    18121 tatcgtgttg ctgccaagag catttcgcca aacaccagga tcgccgggtt ttggtttcga
    18181 tcatcgacgt cgtaggacga gaccgcgtcg atcaatcggt ctattccctg cgacggtgaa
    18241 tcgccggcca gtccgtccag cacctgagcg gcttcctcgc gcgctgcctg cagggccgca
    18301 tcgatcagca ggtcgttcaa cgatgcgaag tgatagtgca ccaaccccgg cggaagtccg
    18361 gcccgttcgg ccaccatccg ggtggtggcc gccccccagc ctcgctcggc gatcaccgct
    18421 accgcggcgg ccatcagcgc ggcccgggtt tgtgcgcctc gctcggcagc tgttggcatg
    18481 cgactacctc aatttggacg atcacattgg gcgtttgacc aaattgtacg ccgcgcggaa
    18541 gccgttcgcg agggtcaaag tggcttgaac gtcgttcggc gccgcttcgg gcgccgccga
    18601 gtcagtgcat gcgagcgctg ccgccgagcc cgacttccag cacgctgccg gtgatgacac
    18661 ccgggtcggt gaccagatag accaccccgc ggctgacgtc ctccggttgc agccacggtt
    18721 gagggatggg gttggccttc atcatgcgcc gcaccagatc gtcgggaact tcctgatcat
    18781 ctccgatccc ggcgggctgc accatcggtg tctgcgtcgt ggtcggacag atgacgttgg
    18841 ccgtgatgcc ttccttggcg acctcgaggg cgacggactt gatcaggccg atgatccccc
    18901 acttggtggc gttgtaggcc gccaattccg ggatgcccat tcggccgccc atcgacgatg
    18961 tcgccacgat cctgccgaag cgttgttggc gcatcaccgg aatggccgcg cgcagggtgt
    19021 ggaacacgcc ggtcaggttg gtgtccatca gctgctgcca aacctggtca cttacctctt
    19081 cgaggcgccc ggtgctgacg atgccggcat tggccagcac gatatcgagg ctgcccagct
    19141 cgcgcaccgt ccgctcaacc gcggtgttca cctgggccgc gtcgcgcacg tcgaccacca
    19201 tcggcaggca acgccggccc agctggccga cgagttcggc ggtggcgagc aggtcttcct
    19261 cgctgcccaa cgggtaggtc agctccgcca tcgggcccgg cgcgtcggcg agggcgatat
    19321 cggccccctg gcccgccagg gccagcgcgt gcgcgcggcc ctgcccgcgg gctccgccgg
    19381 tgatcaaggc gacacgtccg tccaaggcac ccatagcggg ttaggttagc agcctggcgg
    19441 gccggcgacg gcggcccacg cagaccaatt gtggctgcga aatatgctgt gggggagtcg
    19501 atttaatgtc gctgcggcca acatttccgg cggaatcaga cttctgcggt cgcctcttcg
    19561 tcggcatcgg cgggctcgcg gcagcccggc aggtcgtcgg ggggttcgac ctgcagcacc
    19621 ttggctatcg gtacgtcggt tgacgaatgc agcacgatcg agagcgcaat ggtgacggcg
    19681 acgatatcga acaccagctc cttgctggcc aatcccgact gcaatgccag caggccgtag
    19741 accaccgagg caaaaccctt tggtccgaac catgcggcag tcaaccgctc ctgtcggctg
    19801 agctgggtcc gcaccagcga cagcaacatc gcggccggcc ggatcaccgc gatcacgacc
    19861 acggccaaca gccaatcgcg ccaactgagc ccggacaacc gatcgggggt gatcaacgcg
    19921 ccgaacacga tcagcgcggc gaacttggtg acttcggaga gaagatcacc gaacggttga
    19981 aactgctcgg cggcgacatg gtccaaggtg gccagcgtgg agccggcggc aaaggcggcc
    20041 aggtatgggt tggcgtgggt gaggtgacag gccgagtaca ccaccaccgc gatcgccagt
    20101 gggcccaacg gctgcaggtg cgtttcggcc gtcaggatct ttgcccgcca cgcgaacgcc
    20161 acggccgcgg ccaccccgac cccgagcgcc agcccgagaa cgagctccac cccgacccac
    20221 agcacgtcgg agccggcgcc ctgggcggtg gccaggaaga tcatcacgaa cggcagcgcc
    20281 aatccgtcat tgaggccgga ctcgacattg agcagtcggc gcaaccgttc cgggatatcc
    20341 gagcgcccga cgatggccgc cgcgaagacc ggatcggtgg gggacaggat ggcgcccacc
    20401 aggaatgcgg tcggccaatt caggccggtg aggaagtggg ccggcaccgc gatcccgatc
    20461 atggtcaacg gcatcccgac gcccagggcg cgcccggaca gcgtccaggt ctcacgcaat
    20521 tcgcggacat tggcccgctg gccgtcggtg aacagcacgg taaacagcgc cacgtctgcg
    20581 agcgcgacga cgatcgggtc gtttgggccg atgttgtcca acccgagaat cccgggtccc
    20641 agcagggcgc cggcgaccag gaacaacagc gcgctggaca gcaccgtccg ggcggcgacc
    20701 ccggacaggg acacgctgat gagcagtacc acgccgaacg ccaggacaag gctcacagtt
    20761 actccgcttc ggtcgtcggt agccggctgt ggctgctgcg cgaaaacgca gccgctaaca
    20821 gcttcctcga tcacccgagt gtcagccact ccggtcagcg ggcgtgagcg cgggcaaggc
    20881 gacccagggt gagtttgtga gtggcgccgc cgttcacgcc gggttgaaga accccgattg
    20941 cccgctgcca gcgttgaatc cacccgaact cgaggtgccg gagtttccga agcccgagtt
    21001 gcccaagctt ttcacctggc ccgagttgcc cgagttgtcc cagccgctgt cgtaggcacc
    21061 cgagttgaag aatccgatgt tttccaggcc ggaattcaac aagccggcgt tgtgggtgcc
    21121 ggtgttgaag atgccggcgc tcaaggagcc gtcgccgtag ttgaaatagc cggtgctccc
    21181 gccgccggtg ttggagttgc cgaagcccgc gttgtatccg ccactaccgg aattggcggc
    21241 gccggagttg tggccgccgc ttgacgagtt gccgaagccc gaattgtcat cgctggaatt
    21301 gaagaatccg gagttgccgg tgccggagtt gaagaagccc gagttgccgc tgtaggtgcc
    21361 gatgccaccg aagccggtgt tgacgttgcc ggcattccac aaaccggtat tggtgttgcc
    21421 cgaattgaac aaaccggtat tcgtgaagcc ggagttgaag aagcccgtgt tgccggcctg
    21481 cccgggtgcc cccgggaaga tgggactgac gccgttaccg ccggagttga aggcccccgt
    21541 gttgtcgatt cccgcgttgg acaggcccag gtttcccgac ccggcattga acatgccgac
    21601 gttgtgctgg cccgcattga aaatgccgat gtcatgggaa tgcttggtgt tgccgccaga
    21661 gttgaatgcg ccgaggtcag cgacgcccga gttccccaaa ccgacgttgt tcatgcccgc
    21721 gttaagggac ccggtgttgg cggtgcccgc gttccacagg ccggtgttgg tgccgccggt
    21781 attgccgatc ccggtgttga cgctgccgga gttcaccatg ccccagttgg tgctgcccgt
    21841 gttcgccacc ccccagttgt gactgcccga gttgaagaat ccggagttgt cattgcccga
    21901 gttgaacagg ccgctgtttc cgctacccga gttccacccg ccgaaaccga tttgatcggc
    21961 gccggtaagc ccgattccga tgtttccgtt gccggtattg gccaacccga tgttgccgtc
    22021 gccggtattg ccgaagccga ggttgaagct gccggagttg ccaaagccga agttccagcc
    22081 ggcgccgttg gcattgagcc cgccgatacc gatctggttg tcgccggtga gcccgatgcc
    22141 gatgttgttg ttgccgaggt tgccgatgcc cacgttgttg ttgccgacgt ttccaagtcc
    22201 gacgttgtga ttgccgacat ttgcgccgcc cacgttgtac gtcgactggg tgccgtcgag
    22261 cacggcgttg gccagatcgc cgttgccgaa gccgatgttg cccaggccga tgttgcccag
    22321 gccgatgttc ccgatgccga tgttgccggt gcccacgttg tggtatgagg cgccgggata
    22381 ttgcagaccg gcggtgtcca gcgcggcgct tccgttgccg gcaccgatgt tgaaggagcc
    22441 gtagttgccc aaacccacgt tgccgttgcc gccgcccgcg gagctcggac cgttgttgcc
    22501 gccgcccaag ttgtcgttac cggtgttgcc gctgccaatg tttccggtgc cgatgtttcc
    22561 gatgcccaag ttgaatccgg acagacccgg cagactttgc agcgcctgct gccatgacgt
    22621 cagttgtgcg gccgccgccg acaccccgcc gtgatagccc gacatcgcgg tcacgtcttg
    22681 ggcccacatc tgctcatagt cggcctcgac ggccgcaatc gccggcgcgt tgagccccaa
    22741 caggttcgag gtcaccagcg agaccagccg ggtccggttg atcgccacca gcgccgggtg
    22801 caccgtggcc gcccgcgccg cttcaaatgc accggccgct accttggctt gggccgccgc
    22861 cgtggtggcg cgggccgcgg ccaagcccaa ccagcccgca tacggtgccg ccgcgctcgc
    22921 catagcctgc gacgccgcgc cctgccacgc cccctcggcc aggctcgagg tcaccgatcc
    22981 aaacgaggcc actgccgaac ccagctcgcc ggccaacgca tcccaggccg ccgcggcggc
    23041 cagcagcggt ccggatccag cacccgaata catccgcgcg gaattgattt ctggtgccaa
    23101 caccgaaaaa atcatcgccg agcgcccttc ctagctgcat gtttcgagcc ggggcacgat
    23161 ctgagcccat gtgccgacgg gaaaactgaa tgtacagcgg cggcccggcg cgcatctggc
    23221 ttctgacgca acgtcttgag accgatcgac agccggtaac ccggcgcggg cgcgctaccc
    23281 ggtcccggtg c
//
