LOCUS       NC_010612              23439 bp    DNA     circular CON 17-DEC-2024
DEFINITION  Mycobacterium marinum M, complete sequence.
ACCESSION   NC_010612
VERSION     NC_010612.1
KEYWORDS    RefSeq.
SOURCE      Mycobacterium marinum M
  ORGANISM  Mycobacterium marinum M
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
REFERENCE   1  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Davies,J.K.,
            Johnson,P.D., Abdellah,Z., Arrowsmith,C., Chillingworth,T.,
            Churcher,C., Clarke,K., Cronin,A., Davis,P., Goodhead,I.,
            Holroyd,N., Jagels,K., Lord,A., Moule,S., Mungall,K.,
            Norbertczak,H., Quail,M.A., Rabbinowitsch,E., Walker,D., White,B.,
            Whitehead,S., Small,P.L., Brosch,R., Ramakrishnan,L.,
            Fischbach,M.A., Parkhill,J. and Cole,S.T.
  TITLE     Insights from the complete genome sequence of Mycobacterium marinum
            on the evolution of Mycobacterium tuberculosis
  JOURNAL   Genome Res 18 (5), 729-741 (2008)
   PUBMED   18403782
REFERENCE   2  (bases 1 to 6636827)
  AUTHORS   Stinear,T.P., Seemann,T., Harrison,P.F., Jenkin,G.A., Pidot,S.J.,
            Davies,J.K., Small,P.L.C., Johnson,P.D.R., Brosch,R., Cole,S.T.,
            Ramakrishnan,L. and Parkhill,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-AUG-2007) Pathogen Sequencing Unit, Wellcome Trust
            Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge
            CB10 1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000018345.1-RS_2024_12_16
            Annotation Date                   :: 12/16/2024 14:09:37
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,598
            CDSs (total)                      :: 5,546
            Genes (coding)                    :: 5,407
            CDSs (with protein)               :: 5,407
            Genes (RNA)                       :: 52
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 53 of 139
            Pseudo Genes (incomplete)         :: 113 of 139
            Pseudo Genes (internal stop)      :: 14 of 139
            Pseudo Genes (multiple problems)  :: 34 of 139
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:41:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 309580
            Orig. end                         :: 333019
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000854.1.
            DNA and bacteria are available from Dr Lalita Ramakrishnan,
            lalitar@u.washington.edu.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23439
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23439
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23439
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13439](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13439)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(406..415)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(1570..2832)
                     /locus_tag="MMAR_RS01335"
                     /old_locus_tag="MMAR_0273"
     CDS             complement(1570..2832)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392265.1"
                     /locus_tag="MMAR_RS01335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0273"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_012392265.1"
                     /transl_table=11
                     /translation="MNTDDMILISVDDHIVEPPDMFDNHLPAKYLRDAPRLVRNPDGSD
                     VWKFRDSVIPNPALNAVAGRPKEEYGLEPQGLDEIRPGCYQVDERVKDMNAGGILASIC
                     FPSFPGFAGRRFATDDPDFSLALIQAYNDWHIDQWCGAYPARFIPMALPVIWDAQACAT
                     EVRRVSKKGVHALTFTENPATMGYPSFHNDYWNPLWKALCDTNTVMNIHFGSSGNLVTT
                     APDAPIDVLMTLGPMNIVQAAADLLWSRPIKDYPDLKIGLSEGGTGWIPYFLERADRVF
                     EMHSTWTHQDFGGKLPSEVFREHFLACFISDPVGVKLRNMIGIDNIAWEADYPHSDSMW
                     PGAPEELGEVLTANSVPDLEVDKMTHLNAMRWYSFDPFSRIPREQATVGALRKAAAGHD
                     VSTRPRSQHKSGERTSILVEP"
     misc_feature    complement(2140..2142)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2819..4114)
                     /locus_tag="MMAR_RS01340"
                     /old_locus_tag="MMAR_0274"
     CDS             complement(2819..4114)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392266.1"
                     /locus_tag="MMAR_RS01340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0274"
                     /product="cytochrome P450"
                     /protein_id="WP_012392266.1"
                     /sec_met_domain="p450 (E-value: 5.5e-21, bitscore: 73.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNERFVPRLAPLTLAVKSLANPQFIYNAKAQGVRAERTEAGVV
                     TLYRRDDLMRISRHPAVLGPGGRGGNFGNDNPLIPLEIDGEEHKKWRRLLDPLFAPKQM
                     ARLEAAVRNRAAQLVDGFASQTSAELYQAYCAPLPCFTFLELLGAPLEDIEFFTAFKNG
                     VLHPQGETREEIQANQAAAGAMLLEYFTRLVARQRAEGAQGEEVLAVLLRSRIDGQPLT
                     DAELFNIIHLLIFAGLDTVTASMSCILAWLGQHPHERRRLVEDTARIPAAIEELMRYES
                     PAPSGIRYATADIDLGDGLTIRAGEAIHVSWAAANVDPTAHPDPLHVDFDRARFHHLAF
                     GSGIHRCLGSHLARLELRVALEEFLARIPDYAVDTAGLVYDNVSVRTVQQLRITFNANT
                     PSPVDPSQRHAFMAPLTGQRDSVLERNGHEHR"
     misc_feature    complement(3044..3046)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3830..3832)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4115..5278)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="MMAR_RS01345"
                     /old_locus_tag="MMAR_0275"
     CDS             complement(4115..5278)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020727744.1"
                     /locus_tag="MMAR_RS01345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0275"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_012392267.1"
                     /transl_table=11
                     /translation="MTIGLGIPAPPAPRLAPRRVTRQLMVGNVGIGSDYPVAVQSMTTT
                     KTHDVNATLQQIAELTAAGCNIVRVACPRQEDADALPQIVKHSHIPVIADIHFQPKYIF
                     AAIDAGCAAVRVNPGNIKEFDSRVKEVAKAAADTGIPIRIGVNAGSLGKRIIQRYGKAT
                     PEALVESALWEASLFEEHGFGDIKISVKHHDPVVMVAAYQLLATQCDYPLHLGVTEAGP
                     AFQGTIKSAVAFGALLSSGIGDTIRVSLSAPPIEEVKVGTQILESLNLRPRSLEIVSCP
                     SCGRAQVDVYRLANEVSAGLDGLGAPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIF
                     VKGEVIKTVPESQIVETLIEQALRIAEERASETECTDLVGTPVVSEV"
     misc_feature    complement(5036..5038)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5275..7095)
                     /locus_tag="MMAR_RS01350"
                     /old_locus_tag="MMAR_0276"
     CDS             complement(5275..7095)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006899144.1"
                     /locus_tag="MMAR_RS01350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0276"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_408581757.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.6e-77,
                     bitscore: 258.7, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSLINGPQDVQALPADQLPLLAAQIRRRMIETVASTGGHLGAGL
                     GTVELIIALHRVFSSPRDIVVFDTGHQTYPHKLLTGRGDQFVTLRQPGGLSGYPSRSES
                     HHDWVENSHASVSLAWVDGIAKALALQGRGDRRVVSVIGDGALTGGVAWEGLNNLGGAD
                     RAVIIVLNDNGRSYDPTTGAVATHLQALRHGVSSGPNLFETLGFTYIGPTDGHDVESIC
                     SALRQAAALDKPVVVHTVTAKGRGYPPAEADESDRMHACGVIEVATGRPAKPTAASWTD
                     VFEQELVRIADERTDVVGMTAAMRLPAGLGALSRKYPDRVFDSGIAEQHLLACAAGLAS
                     AGAHPVVALYSTFLHRAFDQLLFDVGLHQLPVTLVLDRAGITGPDGASHHGMWDLALLT
                     NVPGLRVACPRDAVRLRQQLRVAIDDTSPNALRYPKGVPDNDIPAVGQIDGVDVLFAGG
                     KPDRDVLLIAVGVMAHPCVDAAERLAAAGVGVSVVDPGWVWPLNPALTELARQHRITVC
                     VEDGVADAGIGSRLNHQIGWLSPRTRTLVLGLPRDYIAHAGRDQILTECGLSGSAISAA
                     CQSALAADSPGSHDRSEPLDPLAPSPLETP"
     misc_feature    complement(6034..6036)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6811..6813)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7039..7041)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7125..8126)
                     /gene="ispH"
                     /locus_tag="MMAR_RS01355"
                     /old_locus_tag="MMAR_0277"
     CDS             complement(7125..8126)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392269.1"
                     /locus_tag="MMAR_RS01355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0277"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_012392269.1"
                     /transl_table=11
                     /translation="MTTVNPSSRSRPRPLADESAATTVLLASPRSFCAGVHRAIEAVER
                     VLDRATGPVYVRKQIVHNRTVVAELQDRGAIFVDELDEIPDPPAPGAVVVFSAHGVSPA
                     VRAAANGRGLEVVDATCPLVTKVHAEAARFAGRGDTVLLIGHLGHEETDGTLGVAPNSM
                     LLVQNADDVTELDLPEDAQVSYLTQTTLAVDETTDVIDALRKRFPKLAEPPTEDICYAT
                     TNRQRAVEAIVRRCDALLVVGSQNSSNSQRLVELARRRGTPAYLIDGPTDIDPHWLDST
                     ATIGITAGASAPPRLVEQVIDALRLRGPINVVESPVTTESVRFALPPKVRVP"
     gene            complement(8123..9139)
                     /locus_tag="MMAR_RS01360"
                     /old_locus_tag="MMAR_0278"
     CDS             complement(8123..9139)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020727747.1"
                     /locus_tag="MMAR_RS01360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0278"
                     /product="hypothetical protein"
                     /protein_id="WP_012392270.1"
                     /transl_table=11
                     /translation="MATHIQRAIAYLTEQHALGYPNAVHKMGSYSTAKFVQLAADHLDL
                     TADQVHRFSTFTCENKAFHVAMITDALQDALDAGHSECQAMVDENIDYLLGCRDEISWR
                     YFPGFEPLPYDADSLGQMTQVLVRAGKATPETLADAFKLAALNAWEDGPISTFFATDPE
                     DRIVINKIWGRGRDDTGRDAEVVANLLYGATLYQDQVGDSPLTPLLEIATKWLTVQQQP
                     MGFWRAAWYVGTSYSTYVVVRQLVAAGGHQSSVDRAVRFLRQAPAPDPLNRALAMLAIT
                     AANCAPDRHDASLLHDTQFHDGSWEAIPLLDNHARIWGSRAVSTAICLKALLRQESQ"
     misc_feature    complement(8729..8731)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9200..9943)
                     /locus_tag="MMAR_RS01365"
                     /old_locus_tag="MMAR_0279"
     CDS             complement(9200..9943)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785677.1"
                     /locus_tag="MMAR_RS01365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0279"
                     /product="hypothetical protein"
                     /protein_id="WP_012392271.1"
                     /transl_table=11
                     /translation="MTIGIRDATEARDIRAAGWAAIMAIIPGIVVNFLTGTPLEPYPSW
                     AWTDERIAGYFAGQQSAIAAQIFLTNAGFVLLLWAVAGVKRAVLTDTRPSLYTDLIIPS
                     AAMATVALLAGNGLYWTAGLRGLSPEFTRLACDLLIPFGYIGSLVSVAITLFCAGIAMR
                     RSAVFPRWLAVATPWTAIPLASAQFFLLADTGPAAPISLISLIPYLLLYLWLATTGIVM
                     LRRSVPITPGTDLRAEVAAIRKQGG"
     misc_feature    complement(9530..9532)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10996)
                     /locus_tag="MMAR_RS01370"
                     /old_locus_tag="MMAR_0280"
     CDS             complement(10001..10996)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392272.1"
                     /locus_tag="MMAR_RS01370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0280"
                     /product="terpene synthase family protein"
                     /protein_id="WP_012392272.1"
                     /sec_met_domain="T1TS (E-value: 5e-38, bitscore: 129.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTAICEFVLPDIYCPFPAAFAHSRHPAATEVELAMTSALPEDG
                     NTLIRRSVSGIHLVDHAGRLYPDVTTAGLHTVTWYFLLFSVFDECSEQQDGGGRTFNPE
                     TLRHIHRTALRLLDHPDASSDDDLDITRIIRPLRRFLNALGDRNARKNFRNAFERSLQA
                     RIWELDHLRTASIPSLAVYPRLRRQSSMAVPLLELHPVLFGLAGSVRSLDHPAIRQLRT
                     MLLNCVLWSNDLLSLAKELRDGSCMNLALVLQKDRGCALQQAVDEVAWLIERETLAYLD
                     LKGQLPRIGIGSSQELASVTALLDREERWHADSIEWHSCPRYQAGPPQRR"
     misc_feature    complement(10238..10240)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10964..10966)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11004..12392)
                     /locus_tag="MMAR_RS01375"
                     /old_locus_tag="MMAR_0281"
     CDS             complement(11004..12392)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020727750.1"
                     /locus_tag="MMAR_RS01375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0281"
                     /product="cytochrome P450"
                     /protein_id="WP_012392273.1"
                     /sec_met_domain="p450 (E-value: 5.6e-75, bitscore: 251.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSIPIAPAALPLLGHTLPLLRNPLSFLLSLPARGDLVRIRIGP
                     ATAVVACTAELTHEILCDDRIFDKGGIFFDRFREMLGDGLGTCPRSQHRRQRRLLQPAF
                     HTQRLPGYAQTMTTEVAATVGRWQNGQIIDVPAEMMAITGRTLLATMFSNSLPNPALRQ
                     ALDDLTAIFAVLYWRMLTPPPLDRLPTVGNRRYHRASARLRHTIGSAVAGRRAAGVDRG
                     DLLSAILASHEVDSSTVAFTDTEVIDQIVSFFIAGTETTALTVAWALYLLAEHPAIEQR
                     VHAEIDPVLAGRAATHADLPRLGLVNRIVTETLRLYPPGWIISRVATADVYLGGHRIPA
                     GATVIFSPYLIHHRPDLYAEPERFDPDRWLPERARAIGRNTYIPFGGGARKCIGDNFGT
                     TEAALALATIAANWRMQRLPGLPVRPAVAASLRPRNLALRVTARTADRVPGEPGRRLTS
                     REIG"
     misc_feature    complement(11580..11582)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12405..13439)
                     /gene="idsB"
                     /locus_tag="MMAR_RS01380"
                     /old_locus_tag="MMAR_0282"
     CDS             complement(12405..13439)
                     /EC_number="2.5.1.29"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0033386 - geranylgeranyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="idsB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354082.1"
                     /locus_tag="MMAR_RS01380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0282"
                     /product="geranylgeranyl diphosphate synthase IdsB"
                     /protein_id="WP_041324247.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.3e-61, bitscore:
                     204.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDTTHVGEAPRAGMAVLRRAQRECEPFLRNIIGSLAEPLATMA
                     GYHFGWWDANGRDAAETSGKSLRAALAFGAARACGDAREAAPAAAAVELIHNFTLLHDD
                     VMDGDSTRRGRATVWRVWGVNNAILLGDALHALAIRTLTDSLGQGVAVNAITRLEQTCL
                     DLCVGQHQDCSFERCTTVTVPDYLRMAAGKTAVLMACACALGAVSARADAATVAAVERF
                     GYELGLAFQIVDDLIGIWGDPARTGKPVGSDLASRKATLPIVVALSSDCEAALELARLY
                     RSDHAMTHREVVHAAELVETAGGRQAAQHFADERMRAAIAALPESMRCSELVALAQLVI
                     DRDK"
     misc_feature    complement(12657..12659)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14302..15657
                     /locus_tag="MMAR_RS01390"
                     /old_locus_tag="MMAR_0283"
     CDS             14302..15657
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012392275.1"
                     /locus_tag="MMAR_RS01390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0283"
                     /product="cytochrome P450"
                     /protein_id="WP_012392275.1"
                     /sec_met_domain="p450 (E-value: 2.9e-82, bitscore: 275.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVAGSPTLRTPPVAPGRLPGLGHLSALARDPLGYLARLRSVADV
                     VTIYLGPRPSYLVTSHDLVRDMLVSQSECFTRGAVFERAGKALGQGLLVSDGEFHRCQR
                     RLLQPAFHHRQTPRYAEVMADAAQTLSRAWRPGVPIEVTHEIHTMALAVVCRGLFHTDL
                     GGSAVSRVERALTGINQGVIWQTLYPFDWLARLPIPVNRRFRSAITDVRDLVTQLISAC
                     RTTGEGREGVLAMLLQARDEETGRPMSDDQVRDEVLTLLLAATETSSTTLSWLFYELDR
                     HPEIERGVARELDDKLANQSITHDNLRDLDLMKRVVDETLRLHTPNSILTRRAVREVQL
                     GQFRIPAGAEVAFSPTAIHRDPTVYDDPLSFKPDRWLSENSAHVPRHMFIPFGMGKHKC
                     IGDSFAITEMHVTAATVLRDWRLSLAPNAHVRERPWAIVQPHGLRMIPFPRR"
     gene            15918..17459
                     /locus_tag="MMAR_RS01395"
                     /old_locus_tag="MMAR_0284"
     CDS             15918..17459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_216865.1"
                     /locus_tag="MMAR_RS01395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0284"
                     /product="phospholipase C"
                     /protein_id="WP_036451754.1"
                     /transl_table=11
                     /translation="MSRRQFMAKLAAASSAGALMSLAGPVIEKAYGAGPCSGHLTDIEH
                     IVLLMQENRSFDHYFGTLSGVRGFDDTTDPAIFDQKGWDPRTQSIDPAGITSPFRFDTT
                     RGPLLNGECVNDPVEGWVAMHTAWNNGANDTWLPSQYSQIRQGNIPACMGYYTRADLPI
                     HYMLADTFTICDDYYCSMLTGTAPNRLYWLSAWIDPDGTNGGPLLNEPNFLPLQPFSWR
                     IMPENLEDAGISWKVYQNKFFGHYINSPISDNGLVQAFKQTADPRSNLARFGIAPTYPQ
                     DFVLDVKANRLPKVSWVVPNIIQSEHPALPVNVGAVAIVNILRTLLSNPAVWEKTALII
                     SYDECGSFFDHVTPPTAPPGTPGEYVTVPDIDAVSGSGGIRGPIGLGYRVPCIVISPYS
                     RGPLVVSDTFDHTSQLRLIETRFGVPVPNLTPWRRSVTEDMTSAFNFAVPPNPSRPKLD
                     PPLLNALPRLPQCVPNAVLGSLGGAAVANPYRVPYPQVPPTQETTPARGTPSGPC"
     gene            17613..19130
                     /locus_tag="MMAR_RS01400"
                     /old_locus_tag="MMAR_0285"
     CDS             17613..19130
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019256747.1"
                     /locus_tag="MMAR_RS01400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0285"
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="WP_012392277.1"
                     /transl_table=11
                     /translation="MTQVTTFPLVDAIVSRRGGSLDGVVVIAAQHLLETTHAMLRSLFR
                     VGLDPRNVAVIGKCYSTHLGVADAMRADGVHVDEFSAAYAPHESFDTEYTRHVERFFAQ
                     SWDRLAAGRAGRVVLLDDGGSLLAAAGAALDGTANIVGIEQTSAGYAKIANCALGFPVV
                     NIARSSAKLLYESPIIAGNVTRCAFDRIEGLDRGDAILITGAGAIGSALADQLRPRHER
                     VDVYDTRVGHPGPIDLTQAIGDYDVIIGATGATSVPTELHDLLRPGVVLMSASSSDREF
                     SGAALRRRAIPDPNCHADLRIADGKLDATLLNSGFPVNFDGSAMCGDESMSLTMALLAA
                     AVLYAASAEAADIDCDHPHLGLTDQGDIVQSFLNIDVPLQALGRLPLLSVGGYRRIELR
                     SGDIVFRQGEPASHFYVVESGELEAFVDGQLVLRLVAGDHFGEIALLSGWRRAATVRAS
                     QPSVLWSLDAAAFSEVLRVDATMRELAHQAIHSRVSRVVGAPKSSSV"
     gene            complement(19200..20576)
                     /locus_tag="MMAR_RS01405"
                     /old_locus_tag="MMAR_0286"
     CDS             complement(19200..20576)
                     /NRPS_PKS="Domain: Abhydrolase_1 (62-260). E-value: 3e-11.
                     Score: 35.3. Matches aSDomain:
                     nrpspksdomains_MMAR_RS01405_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014588448.1"
                     /locus_tag="MMAR_RS01405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0286"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_012392278.1"
                     /sec_met_domain="PF00561 (E-value: 5.9e-08, bitscore: 31.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQAPRTPRTRYARCGDLDIAYQVIGDHPIDLLVIPGASIPVDTI
                     DSEPSMYRFHRRLASFSRLIRFDHRGVGLSSRVSSPDALGPRFWAEDAIAVMDAAGCQE
                     ATILASGFTATTALVLAADYPERVRSLVLINASARTLHAPDYELGIRSNTAEPFLTLGT
                     DPDAVEQGFDVLRIMAPSVAHDDAFRDWWDLAGNRAASPSTARAFINAVQASDARDSLP
                     HITAPTLILHRVGTKFVPVEHGRYLAEHIAGSRLVELPGSDSLYWVGDTAALLDEVEEF
                     ITGVRGGFVTERVLTTVMFTDIVGSTQRAATVGDLRWRDLLDNHDNLVRHEIQRFGGRE
                     VNTAGDGFVATFSSPSAAINCADAVVDAVAVLGIEVRVGIHAGEVEVRGADVAGLAVHI
                     GARVCALAGSSEVLVSSTVRDIVTGSSHRFAERGEHELKGVPGRWRLCALVREHLTGQR
                     "
     aSDomain        complement(19797..20390)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MMAR_RS01405_Abhydrolase_1.1"
                     /evalue="3.00E-11"
                     /label="MMAR_RS01405_Abhydrolase_1.1"
                     /locus_tag="MMAR_RS01405"
                     /protein_end="260"
                     /protein_start="62"
                     /score="35.3"
                     /tool="antismash"
                     /translation="RLIRFDHRGVGLSSRVSSPDALGPRFWAEDAIAVMDAAGCQEATI
                     LASGFTATTALVLAADYPERVRSLVLINASARTLHAPDYELGIRSNTAEPFLTLGTDPD
                     AVEQGFDVLRIMAPSVAHDDAFRDWWDLAGNRAASPSTARAFINAVQASDARDSLPHIT
                     APTLILHRVGTKFVPVEHGRYLAEHIAGSRLVELP"
     gene            complement(20579..21184)
                     /locus_tag="MMAR_RS01410"
                     /old_locus_tag="MMAR_0287"
     CDS             complement(20579..21184)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020785686.1"
                     /locus_tag="MMAR_RS01410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0287"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_012392279.1"
                     /transl_table=11
                     /translation="MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANIEDV
                     ATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPREAVIEAFTLGVR
                     LIQDSPLYSRIAESEPELFGMFSRSHVFPIGQFADGIAHTLRRCGADAPDADLANIADI
                     LLRVAVGIIMFPTERLDTSDDAAVREYAARYLIPIITL"
     gene            21373..22323
                     /locus_tag="MMAR_RS01415"
                     /old_locus_tag="MMAR_0288"
     CDS             21373..22323
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011742333.1"
                     /locus_tag="MMAR_RS01415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0288"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_012392280.1"
                     /transl_table=11
                     /translation="MATELTAGVDFDTGVREALPMPIDRPVDDEIVAQRLGPTSLIWKF
                     YGDVRTQLFGFQRAAGTENCIEQLGQGVLDHSVVFSDTLGRAKRTGPPLMRTVYSEDPH
                     GWGRTVRDFHKPIKGTIGDGSRYHALNPELFYWAHATFVDQILYNTDTFIRRLSRAEKE
                     QIFEESKIWYGLYGVSDRSQPQTYDEFVAYWDGMLDRFVPHKTVLYGTGYLRKGIPGPR
                     KLPALIWRILSAPLNAYARLVIVGTLPPQMREVCDLDWNAKKERRFQRFAALIRGLNPV
                     LGRLPVRLIYLPWAAQAWTRSGVDPRRLHRRAVST"
     gene            complement(22344..22607)
                     /gene="rpsR"
                     /locus_tag="MMAR_RS01420"
                     /old_locus_tag="MMAR_0289"
     CDS             complement(22344..22607)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011742332.1"
                     /locus_tag="MMAR_RS01420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0289"
                     /product="30S ribosomal protein S18"
                     /protein_id="WP_011742332.1"
                     /transl_table=11
                     /translation="MKKKPRRTRRPIAAPATPAKKNLLDSLGVSEVDYKDISRLRTFIS
                     DRGKIRSRRVTGLTVQQQRQIATAIKNAREMALLPYPASRPQ"
     misc_feature    22592..22606
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            complement(22614..22919)
                     /gene="rpsN"
                     /locus_tag="MMAR_RS01425"
                     /old_locus_tag="MMAR_0290"
     CDS             complement(22614..22919)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_216572.1"
                     /locus_tag="MMAR_RS01425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0290"
                     /product="30S ribosomal protein S14"
                     /protein_id="WP_011742331.1"
                     /transl_table=11
                     /translation="MAKKSKIVKNNKRRDIVARYAQRRAELKQIIQSPTSSYEQRLDAQ
                     RALSRQPRDASAVRLRNRDAIDGRPRGHLRKFGLSRVRVRELAHAGQLPGVRKASW"
     gene            complement(22920..23084)
                     /gene="rpmG"
                     /locus_tag="MMAR_RS01430"
                     /old_locus_tag="MMAR_0291"
     CDS             complement(22920..23084)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005063154.1"
                     /locus_tag="MMAR_RS01430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0291"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_011742330.1"
                     /transl_table=11
                     /translation="MARNEIRPAVKLRSTAGTGYTYITRKNRRNDPDRLILSKYDPVIR
                     KHVPFREER"
     gene            complement(23084..23320)
                     /gene="rpmB"
                     /locus_tag="MMAR_RS01435"
                     /old_locus_tag="MMAR_0292"
     CDS             complement(23084..23320)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_216574.1"
                     /locus_tag="MMAR_RS01435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MMAR_0292"
                     /product="50S ribosomal protein L28"
                     /protein_id="WP_011742329.1"
                     /transl_table=11
                     /translation="MSARCQVTGRTVSFGNTVSHSHRRSRRRWSPNIQLKTYYLPSENR
                     RIKLRVSAKGIKVIDRDGIEATVARLRRAGEQI"
     misc_feature    23344..23359
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.57"
                     /tool="antismash"
     misc_feature    complement(23346..23359)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.89"
                     /tool="antismash"
     misc_feature    23346..23360
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.93"
                     /tool="antismash"
     misc_feature    complement(23347..23362)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.52"
                     /tool="antismash"
     misc_feature    23400..23415
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 23.7"
                     /tool="antismash"
     misc_feature    complement(23400..23418)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.47"
                     /tool="antismash"
     misc_feature    23402..23416
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 27.11"
                     /tool="antismash"
     misc_feature    complement(23403..23418)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.57"
                     /tool="antismash"
     misc_feature    complement(23404..23415)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.88"
                     /tool="antismash"
ORIGIN
        1 ggcgcgtggt gttcatgccg gagcagatat gggtgccgaa accgaaggtc gcgtgatgtg
       61 gtcccgtgcg gtcgattcgg aactcgtcag gatcgggcgg atatgcttcc ggatcccggt
      121 tggctgaccc gatggctagc agcagcggtg ttccggcggt gagttccgtg cctcgaatga
      181 ccacatcgcg ggtgatcatg cgagggatga agagcgctgg cggttccagg cgctcaccct
      241 cggcgagcgc caaccgcagg cggctgcggt cgcgccggat gcggtccagt tcgtccggcc
      301 gttgcagtag gagggtgagc gtgttcaaga actgtcgagt ggtggtgtcg gttgctgcta
      361 gcagcagcga acgtagaaac gaagtgatct gctcgtcatc aagaacgccg ccttcatact
      421 cggctcggat gagtgaacta atgaggtcgt ttctcgaagc gccggccgcc cgtttgcgct
      481 gaacaatcgg aagcagccgg tcccagctgc gggccgacgc ctcggtcgcc ttttgaaacc
      541 tgagcagaaa ttggtctgct tgtgccggat ccggggtgga ccacaacgcg agcaggatgg
      601 tcaggacgtc agcatggaac tcttcgtagt tgtctttgaa gtcctctaag cccaggattt
      661 cgtagatcgc gcgcaacggg tactcgagcg ccatcgcaat gaggtcggcg ccccgcttgg
      721 aagccaggtc cgcgacgtac tttgcggcaa gtggccggaa gatgctctcg tcccaggagc
      781 tcaacaactt gccgccaaac acggactgga gatagccgcg ccactggcgg tgctccgcgc
      841 cgtccatcgc gaggatcgat cggccgatca aaggtccttg cgagatttcc cagatgctgc
      901 tggagaaggt ctcatggttg cgcaggatgg ccatcacgtc atcatggcga aagaccgtgt
      961 gcgtttcgcc ggcgtgctga cccatgtatg aaggcgcgcc aagagcaacc atgatgtcgc
     1021 ccttcataac cggtgtctca cgtcggcgtt ctgcgagcat cgggtagggg tcatccatgc
     1081 ttgacaggcg gaaggcttcc ccgagttctt gtgataactc ggcaaccgat gggctcataa
     1141 gtttcgacgc taacacggcg gcccggccgt tttaaggccc gcgatactgc attgcgcaaa
     1201 attgagtcat ttgactgaac ctgttggggc aaaaggtatt aaagctagtc gaagcgatcc
     1261 ccacctgact gccgcgaaag ccccgtcacc gcccacgaat tccgctcccg ccgcctcgaa
     1321 ggtgcgctgc ccgcgggtgc caaattgctc gcgtgccgaa cctaaagatg ccgaatctga
     1381 tctcgccgcg tttgtcgaga tcaactggat tgcaacggca ttgagtcgga gtgtccgcgc
     1441 gcgcacggac tggccgaggt cgctgccgca tctcgccgag ttcggcgatg cgcgatgacg
     1501 cgcggctctc gaggctggtt agtccgcgcg attatgtccc gcaggctgat tcgtttgctg
     1561 cccaaggcat cacggttcga ccagtatgct ggtccgctca ccgctcttgt gttggctacg
     1621 tggccgcgtg gacacatcat ggccggctgc ggctttgcgc aacgcgccga ccgttgcctg
     1681 ctcgcgaggg atgcggctaa acgggtcaaa cgagtaccag cgcatcgcgt tgaggtgagt
     1741 catcttgtcc acttcgaggt caggcacgct gtttgcggtc aaaacctccc ctagctcctc
     1801 gggcgcaccc ggccacatcg aatcgctgtg tgggtagtcg gcttcccagg cgatgttgtc
     1861 gatgccgatc atgttgcgca gcttgacacc caccggatcg ctgatgaagc atgccaggaa
     1921 atgttcccgg aacacctcgg acgggagctt gccgccgaag tcctggtggg tccacgtcga
     1981 atgcatttca aacacgcggt ccgcccgctc cagaaagtag gggatccagc ccgtgccgcc
     2041 ctcggacaac ccgatcttga ggtccgggta gtccttgatc ggtctggacc acaacagatc
     2101 cgcggccgcc tgcacaatgt tcatcggccc tagagtcatt aacacatcta tcggtgcgtc
     2161 gggtgctgtc gtcaccaggt tgccggagga tccgaagtgg atgttcatca cggtgttggt
     2221 gtcgcacagc gctttccata gtggattcca gtagtcgttg tgaaagctgg ggtaacccat
     2281 cgtcgcggga ttctcggtga acgtcagtgc gtgcacgccc ttcttcgaga cccgccgcac
     2341 ctctgtcgcg cacgcctgcg catcccagat gaccggcaac gccatgggga tgaaccgtgc
     2401 cggatatgcc ccgcaccatt ggtcgatatg ccagtcgtta taggcctgta tcaatgccaa
     2461 cgaaaaatcc ggatcgtcgg tcgcgaaccg ccggccggca aatcctggga aggagggaaa
     2521 acaaatcgag gccaggatgc ccccggcatt catatccttg acccgttcgt ccacctgata
     2581 gcaaccgggc cgaatctcgt ccagaccctg cggctccagg ccgtattcct ccttcggccg
     2641 cccggctacc gcgttgagcg ccggattggg gatcacgctg tcacggaact tccatacgtc
     2701 ggagccgtct ggattacgca ccagccgcgg cgcgtcccgc agatacttcg cgggcagatg
     2761 gttatcgaac atatcgggcg gctcgacgat gtggtcatcg acgctgatca agatcatgtc
     2821 atcggtgttc atggccgttc ctttccaaga cgctgtcccg ctgccccgtc agcggagcca
     2881 tgaaggcatg gcgttgagat ggatcaactg gcgatggggt gttggcgttg aaggtgatgc
     2941 gcagctgctg cacggtgcgc accgacacgt tgtcgtagac cagcccggcc gtgtccaccg
     3001 cgtagtcggg aatgcgagcc aagaattctt ctagagcgac ccgtaattcg agtcgcgcca
     3061 gatgcgatcc gagacagcgg tggatgccgc tgccgaaggc gaggtggtgg aaccgggcgc
     3121 ggtcgaagtc cacgtgcagg ggatccggat gggcggtggg atctacgttg gcagccgccc
     3181 agctgacgtg gatcgcttct cccgcccgga ttgtcagccc gtcgccgagg tcgatgtcgg
     3241 ctgtggcgta gcggatgccg ctgggcgccg gcgattcgta gcgcatcagc tcctcgatcg
     3301 cagccgggat ccgtgcggtg tcctcgacca ggcgacggcg ctcgtgcggg tgttggccca
     3361 gccaggccag gatgcacgac atggacgcgg tgaccgtgtc caagccagcg aatatcagca
     3421 gatggatgat gttgaacagt tccgcatcgg tcaacggttg gccgtcgatc cgtgagcgca
     3481 acaacaccgc gagcacttcc tcgccctgag ctccttcggc acgttgtcgg gccacgagcc
     3541 tggtgaagta ctccagcagc atggccccgg cagcggcctg gttggcctgg atctcctcgc
     3601 gggtctcccc ttgcggatgc aacacgccgt ttttgaatgc cgtgaagaac tcaatgtctt
     3661 cgagcggagc gccgaggagc tccagaaacg taaagcatgg cagcggcgcg cagtaggcct
     3721 gatacagttc ggcgctagtc tggctggcaa agccgtcgac cagttgcgcg gcacggttgc
     3781 gaacagcggc ttccaaccgt gccatctgct tgggcgcgaa gagcggatct aacagccgtc
     3841 gccacttctt gtgttcctca ccatctatct ccaacgggat cagcggattg tcgttgccga
     3901 aattcccccc gcgaccaccc gggcccagta ccgccggatg acggctgatc cgcatcaggt
     3961 catcgcgacg gtacagtgtc accactcccg cttcggtgcg ttcggcacgc acaccttgtg
     4021 ctttcgcgtt gtaaataaac tgtgggttgg caaggctttt caccgccaag gtcaacggcg
     4081 ccagccgggg aacgaaccgc tcattgccct ccattcagac ctcactcacg accggtgtac
     4141 cgacgagatc ggtgcattcg gtctcggagg cccgctcttc ggcgattcgc aatgcctgct
     4201 caatcaacgt ctcaacgatc tgcgactccg gcacggtctt gatcacctcg cccttgacga
     4261 atatctgccc cttgccgttt ccggaggcca cgcccaggtc cgcctcgcgt gcctcaccgg
     4321 gaccgttgac tacacaaccc atcaccgcca cgcgcagcgg agcgccaaga ccgtctaggc
     4381 ccgcgctgac ttcatttgcc agtctgtaga cgtcaacctg cgcgcgccca caggacgggc
     4441 acgagacgat ctccagcgat cgcgggcgca ggttcagtga ctcgaggatt tgggtgccga
     4501 ccttgacctc ttcgataggt ggggccgaca gcgaaacccg gatggtgtcg ccgatgccgc
     4561 tggagagcag ggcgccgaac gcgaccgccg acttgatcgt gccctggaac gcaggcccgg
     4621 cctcggtgac cccgaggtga agtggatagt cgcactgcgt cgccaaaagc tggtacgcgg
     4681 ccaccataac gaccgggtca tggtgcttga cgctgatctt gatatcaccg aagccgtgct
     4741 cctcaaacag cgatgcctcc cacagcgcgc tctcgaccag cgcctcgggg gtcgctttgc
     4801 cgtacctctg gatgattcgc ttgcccagcg agccggcgtt gacgccgatg cggatcggga
     4861 tgccggtgtc cgccgcagcc ttggccactt cttttacccg gctatcgaat tccttgatgt
     4921 tgcccgggtt tacccgcacc gcggcgcagc cggcgtcgat cgcggcgaag atgtatttcg
     4981 gctggaaatg gatgtccgcg atgaccggaa tgtgactgtg cttgacgatc tgcggtaagg
     5041 catcggcgtc ttcttgtcgt gggcacgcta cccgcacaat gttgcagccg gcggcggtca
     5101 gctctgcgat ctgctgcaga gttgcgttga catcgtgagt cttggtggtc gtcatcgact
     5161 gcaccgcaac gggatagtcg ctcccgatac cgacattgcc gaccatcagt tggcgagtca
     5221 cgcgtcgcgg cgctagccga ggcgcgggcg gtgcggggat gcccagacca atggtcatgg
     5281 tgtctccaga ggggagggcg ccaatggatc cagcggttcg gatctgtcat ggctgccggg
     5341 tgagtccgcg gccagcgccg actggcatgc cgcgctgatt gcggaaccgg acaacccaca
     5401 ttcagtaagg atctggtcgc ggcccgcgtg cgcgatgtag tcgcgcggca gccccaggac
     5461 aagggtgcgg gtccgggggc tcagccaccc gatctggtgg ttgaggcgtg agccgatccc
     5521 tgcgtcggcg accccgtcct cgacacatac ggtgatgcgg tgttggcggg caagctcggt
     5581 gagcgccggg ttcagcggcc acacccagcc aggatcgaca acgctgaccc cgaccccggc
     5641 cgcagcaagg cgctctgcgg cgtcgacaca ggggtgcgcc atgacaccca cggcgatcag
     5701 caacacgtcg cgatcgggtt tgccgccggc gaaaaggaca tcgaccccgt caatctggcc
     5761 caccgcaggg atatcgttgt cgggcactcc ttttgggtat cgcagcgcgt tcggtgacgt
     5821 gtcgtcgatc gcgacacgca gctgctggcg cagccttact gcgtcacggg ggcaggcgac
     5881 acgcaagccg ggcacattcg tcagcagcgc caagtcccac atcccgtgat ggctggcgcc
     5941 gtcgggtccg gttatcccgg ctctgtcgag gaccaaggtc acggggagct ggtgcagtcc
     6001 gacgtcgaat agcaactggt cgaaggctcg atgtaagaac gtggaataca gtgccacgac
     6061 gggatgtgcg cccgcgctgg ccaggcccgc ggcacacgcc aagaggtgtt gttcggcgat
     6121 gccggagtcg aaaacccggt cggggtattt gcgtgacagc gcgccgaggc cggccggcag
     6181 ccgcatcgcc gcggtcatac cgacgacgtc ggtccgttcg tcggcgattc ggacgagctc
     6241 ttgctcgaat acgtcggtcc agcttgctgc agtgggtttg gccggccggc cggtggctac
     6301 ctcgatgaca ccgcaggcat gcatgcggtc gctctcatcc gcttcggccg gtgggtagcc
     6361 gcgtcccttc gcggtgacag tgtggacgac aacgggcttg tccagtgcgg ccgcttgccg
     6421 cagcgccgaa caaatcgatt cgacgtcgtg cccgtccgtg gggccgatgt aggtaaagcc
     6481 caatgtttcg aacagattgg gccctgagct gacgccatgg cgcagcgcct gcaggtgagt
     6541 ggctaccgcg ccggtcgtgg gatcgtatga gcgcccgttg tcgttgagca caatgatcac
     6601 ggcgcggtcg gcgccgccca gattgttcag gccctcccat gccactccac cggtaagagc
     6661 gccgtcgcca atcacgctca cgacacggcg atcacctcgc ccctgcaggg ccaaggcttt
     6721 ggcaatgccg tccacccacg ccaaactcac cgatgcatgc gaattttcta cccaatcatg
     6781 gtgggattcg ctgcggctgg gatatcccga taagccaccg ggttggcgca gggtgacaaa
     6841 ctggtcgccg cgaccggtga gcagtttgtg cgggtatgtt tgatgtccgg tatcgaacac
     6901 cacgatgtca cgcggcgagg aaaacacccg gtgcagggcg atgatcaact cgacggtacc
     6961 cagtcccgcg ccaaggtggc ccccggtgct ggccaccgtc tcgatcatgc gtcgacggat
     7021 ctgcgcggcc aacaacggta attggtcggc gggcagtgcc tggacatcct gcggaccatt
     7081 gatgagtgaa agcaggtcgg ctcgatcggc acgcatggtg atgctcacgg gactcgtact
     7141 tttggcggca gggcgaagcg caccgattcg gttgtgaccg ggctttcgac cacattgatc
     7201 ggcccgcgca agcgcagcgc atcgatcact tgctcaacca gccggggtgg agccgaagcg
     7261 ccggccgtga tgccgatcgt ggccgtcgag tccaaccagt gcgggtcgat atcggtgggg
     7321 ccgtcgatga ggtatgcggg ggtgcctcgg cgccgcgcca gttcgaccaa ccgctgcgag
     7381 ttcgacgagt tctgtgaccc aaccaccaac agcgcatcgc accgccggac aatagcctca
     7441 accgcccgct gccgattcgt tgtcgcgtag cagatatctt ctgtaggcgg ttctgcaagt
     7501 tttgggaacc gtttgcgcag cgcgtcaatg acgtcggtgg tttcgtccac cgccagcgtc
     7561 gtctgagtta ggtaagacac ttgggcgtct tcgggaagat ccagttccgt cacgtcatcg
     7621 gcgttctgca ccaacaacat tgaattcggg gcaactccga gggtgccgtc ggtctcttca
     7681 tgtccaaggt ggccgatcaa tagcacggta tcgccgcgcc cggcgaaccg cgcggcttcc
     7741 gcatgaacct ttgtgaccag cgggcaggtg gcgtcaacga cctcgagtcc gcgcccgttg
     7801 gcggccgcgc gtactgccgg ggagacgcca tgtgcggaga agaccacgac ggcacccggt
     7861 gcgggaggat cgggaatctc atcgagctcg tcaacgaaaa ttgctccgcg gtcttgtagt
     7921 tcggcgacca ccgtgcggtt gtgcacgatc tgcttgcgta cgtacaccgg cccggtagca
     7981 cggtcgagca cacgctcgac cgcttctatc gcccggtgta cgccggcgca gaacgaacgt
     8041 ggcgaggcca acagaacggt ggtggctgcc gactcgtctg cgagcgggcg cggtcgcgaa
     8101 cgcgatgagg ggttgacggt ggtcattgag actcctgccg cagcaatgcc ttgaggcaga
     8161 tggcggtgct gaccgctcgg cttccccaga tccgtgcgtg gttatcgagt agggggatgg
     8221 cttcccagga gccgtcgtga aactgggtgt cgtgcaggag cgacgcgtcg tggcggtcgg
     8281 gtgcgcagtt tgccgcggtg atcgccagca ttgccagcgc acgattgagc ggatcgggcg
     8341 ccggcgcctg ccggagaaat cggacggcac gatcaactga tgactggtgg ccgcccgcgg
     8401 ccaccagctg gcgcactacg acgtaggtgc tgtacgaggt tccgacatac catgccgcgc
     8461 gccagaaccc catgggttgt tgctgaactg tcaaccattt ggttgcgatt tccagcagtg
     8521 gggtcaatgg cgagtcgcct acctggtctt gatacagcgt cgcgccgtag aggaggttgg
     8581 cgacgacttc cgcgtcacgt ccggtgtcgt cgcgcccacg cccccatatc ttgttgatga
     8641 cgattctgtc ttcggggtcg gtcgcgaaaa aggtgcttat cgggccgtcc tcccatgcgt
     8701 tgagggctgc aagcttgaac gcgtccgcta aggtttcggg cgtcgctttg cctgctcgaa
     8761 cgagcacttg cgtcatttgc ccaaggctgt cggcgtcgta gggcaatggc tcgaagccgg
     8821 ggaaatagcg ccaagaaatt tcatcccggc agccgagtag gtagtcgatg ttctcgtcca
     8881 ccatggcttg gcattccgag tggccggcgt cgagagcatc ttgcagggca tcggtgatca
     8941 ttgccacgtg gaacgccttg ttctcacagg tgaatgtgga gaatctgtgc acctgatccg
     9001 cggtgaggtc aagatgatcg gcggcgagtt gaacaaactt cgccgtggaa taggacccca
     9061 tcttgtgtac ggcgtttgga taacccaatg cgtgctgttc ggtgagatac gctattgctc
     9121 gctgaatatg cgtcgccatg taattctcca aagtgccggt tttgggtttt cggggagtct
     9181 gagatctgcc gggactgcgt cagccgccct gtttgcgtat cgccgccacc tcggcccgga
     9241 gatcggtgcc gggcgtgatc gggacgctgc ggcgcaacat gacgatgccg gtggtcgcca
     9301 gccagaggta cagcaagagg tacgggatca agctgatcag gctgatgggc gccgccggtc
     9361 cggtatcggc caacaagaag aattgggcgc tggccagcgg gatggccgtc cagggtgtgg
     9421 cgaccgccag ccacctgggg aaaacggcgc tgcgacgcat cgcaatgccc gcgcagaaca
     9481 gtgtgatcgc cacactgacc agggatccga tgtagccgaa gggaatgagt aaatcgcaag
     9541 cgagtcttgt gaactccggc gagaggccgc gtaggccggc ggtccagtaa aggccattgc
     9601 cggccagcag cgcgacggtc gccatggcgg cggacgggat gatcaggtcg gtgtatagcg
     9661 atggacgggt atcggtgagc accgctcgtt tcaccccggc gactgcccat agcagtagta
     9721 cgaacccggc attggtgaga aagatctgtg cggcgatggc cgactgctga ccggcgaaat
     9781 agccggcgat ccgctcgtcg gtccaggccc aacttggata aggttccagc ggggtgccag
     9841 tcaggaagtt caccacgatt ccggggatga ttgccatgat ggctgcccac cccgcggctc
     9901 ggatgtcgcg ggcttcggtc gcgtcccgga tgccgatcgt catcgttggt ctccaatcgt
     9961 ggtgggtatt tgaccgatca actgatgtcg cgccgccgtg ctatcgccgc tgcggcgggc
    10021 cggcttgata gcgcgggcag ctatgccatt cgatggagtc ggcgtgccag cgttcttcgc
    10081 gatcgagaag cgctgtgacg gaggccaatt cctgcgatga accaatgcct atccgaggga
    10141 gttgcccttt gaggtcaaga taggcaaggg tttctcgctc gatcagccat gcaacctcgt
    10201 caacggcttg ctgtagcgcg cacccgcggt ctttctgtaa gaccagggcc agattcatgc
    10261 aagacccgtc gcgcagctcc tttgcgagcg aaagcaggtc attgctccac aacacacagt
    10321 tgagcagcat cgtgcggagt tgtcggattg cgggatggtc cagggaacgg acagagccgg
    10381 ccagcccgaa aagcaccgga tgaagctcga gcaaaggaac agccatcgag ctctgccgcc
    10441 gcaaccgggg atacaccgcc agggagggaa tactggcggt tcggaggtga tcgagttccc
    10501 atatccgcgc ttgcagggac ctttcgaacg cgttacgaaa gttcttgcgc gcattccgat
    10561 cgcccagggc gttcagaaat cgcctcaacg gccgaataat tcgagtgata tcgagatcat
    10621 cgtcgctgga cgcgtcgggg tggtccagca gccgaagggc cgtgcggtga atgtggcgta
    10681 gcgtctcggg gttgaaagtc cgcccgccac cgtcttgctg ttcggagcac tcatcaaaca
    10741 cggagaagag cagaaaatac caggtgacgg tgtgcaaccc cgctgtggtc acgtcgggat
    10801 acaggcgccc ggcatgatcc acgagatgga tgcctgagac ggagcgccga atcagagtgt
    10861 tgccgtcttc gggtagcgcg ctcgtcatgg ccagctctac ttcggtcgct gccggatgac
    10921 gagagtgcgc aaaggcggcg ggaaaaggac agtagatatc gggtaagacg aattcgcaaa
    10981 tggcggtcac ggacacctcc ggctcaaccg atttcgcggc ttgttagacg ccggccgggt
    11041 tcgccaggaa ctcggtcggc cgtacgtgcg gtgacacgca aagcgagatt gcgtgggcgc
    11101 agtgacgccg ccacggccgg gcggaccggc aggccgggaa ggcgctgcat ccgccagttg
    11161 gcggcaatgg tcgccagggc gagtgcggcc tctgtggtgc cgaagttgtc gccgatgcac
    11221 ttgcgggccc cgccgccgaa tgggatgtag gtgttgcggc cgatagcccg ggcacgctcg
    11281 ggtagccatc ggtccgggtc gaagcgttcg ggctcggcat agagatcggg acgatggtgg
    11341 atcaggtacg ggctgaagat gaccgtcgcc ccggccggta tccgatgccc accgaggtag
    11401 acatcggcgg tggccacgcg gctgatgatc cacccaggcg gataaaggcg cagggtctcg
    11461 gtgacgatcc tgttgaccag ccctagccga ggcaggtcgg cgtgggtagc cgccctgccc
    11521 gccaggaccg gatcgatctc ggcgtgcacg cgttgctcga tggcgggatg ttcggccagt
    11581 aagtacagcg cccaggccac cgtaagggca gtggtctcgg tccccgcaat gaaaaacgac
    11641 acaatctggt cgatgacctc ggtatcggtg aaagctactg tgctgctgtc gacttcatgc
    11701 gaggccagga tcgccgagag aaggtcgcca cggtcgacgc cggctgctcg gcggcccgca
    11761 accgccgaac cgatggtatg gcgtagccga gcgctggcgc gatgatagcg acggttgccg
    11821 acggtgggca gccgatccag cggtggcggc gtcagcatcc gccagtacag gaccgcgaaa
    11881 atggcggtca ggtcatcgag tgcctggcgc aatgccgggt tagggaggct attcgagaac
    11941 atcgtggcga gcagggtccg gccggtgatc gccatcatct ccgcgggtac atcgatgatc
    12001 tggccgttct gccagcgccc gacggtcgcg gccacctcag tggtcatggt ctgcgcataa
    12061 ccaggcaacc gctgcgtatg gaaggccggt tgcagaaggc gccgctgccg ccggtgctgg
    12121 ctacgggggc aggtgcccag accatcgccc agcatctctc ggaaccggtc aaagaagatg
    12181 ccgcccttgt cgaaaattcg gtcatcacag aggatttcgt gggtgagttc cgccgtgcac
    12241 gccaccacgg cggtggccgg cccgattcgg atgcgcacca ggtcgcctcg ggcgggcaac
    12301 gacagcaaga acgacaacgg attacgcagc agcggcaagg tatggccgag tagtggcaac
    12361 gcggcgggcg cgatgggaat cgaggtaggc atcgtcgaca cacctcactt gtcccgatcg
    12421 atcaccagct gcgccaatgc cacgagctca ctgcatctca ttgattcggg cagcgccgcg
    12481 atcgcggcgc gcatccgttc atcggcaaag tgctgcgcgg cctgcctgcc gcccgcggtc
    12541 tccacgagtt cggcggcatg aacaacctca cggtgggtca tggcgtggtc ggacctgtac
    12601 agccttgcca gttcgagggc cgcttcgcag tcagagctaa gcgctacaac gatcggtaag
    12661 gtcgccttgc gactggccag atcactgccg accggctttc cggtccgggc agggtccccc
    12721 cagatgccaa tcagatcgtc cactatctga aacgccaggc cgagctcgta accaaaccgt
    12781 tccaccgcgg ctacggtcgc cgcgtccgcg cgggcgctta ccgcacccaa tgcgcacgca
    12841 cacgccatca acacggcggt ctttccggcc gccatccgca agtaatccgg cactgttacg
    12901 gtcgtgcatc gctcaaatga gcaatcctgg tgctggccca cacacaggtc gaggcacgtt
    12961 tgctccagac gggtgatcgc gttcacggcc accccctgcc caagcgagtc ggtaagcgtc
    13021 cggatcgcca gggcatgtag cgcatctccc agcaggatcg cgttattcac tccccatacc
    13081 cgccatacag ttgccctgcc cctgcgggtc gaatcaccgt ccatcacatc gtcgtgaagc
    13141 agcgtgaagt tgtgaatcag ctccacggct gccgccgcgg gggcggcttc gcgagcatct
    13201 ccgcaggccc gggccgcccc gaaggcaaga gcggcccgca gcgacttacc cgaggtctct
    13261 gccgcgtcgc gcccgttggc atcccaccaa ccgaagtggt atccggccat cgtggccaac
    13321 ggctcggcca acgacccaat tatattccgc aggaacggtt cacactcacg ctgagcacgt
    13381 ctcaagacgg ccattccagc gcgaggtgcc tcgccaacgt gtgttgtatc gaccgacatc
    13441 cacggcctcc tggcatcgca tgtcgctagg cccacacagc ctcagcatgt attgagcgct
    13501 gagagatcaa ctgaaagtta tttgtcgacg gcacttttgg cagcaacagc tgggtttccg
    13561 agctgtagcg ccaaccggcc atccaccaga acgcgatgcg tgaagcgtgc tacccgccag
    13621 ttccctcgcc gcaccgacta gggaacggcg ctccctgggg ccgaatgtgc cgggtcgtcc
    13681 gccggtggcg gggaaggggg tgcaggcggg aagcctcgtc gagccacaga ctcggccggc
    13741 caaagcccac ggatgaacat cactggtgcc cgggcatttt ccatttgctg ctccttgccc
    13801 ccgtggtccc ccctgatagc gaagacatgc caagagtcgc acctagccga cctagcggga
    13861 tcagtcagat gactcaaacg tgtcgggcgc agcatcgaag acatcgcgaa cccgggtaac
    13921 cccctgcggc cacatcgacg gcccgacggc tccggtgggc tgggggaagg ccgctaccgc
    13981 atggaccagc gcgggcggcg acggcggatc cggtaggccg tcggacaagg cgtatttgga
    14041 cgggaaggat ttgaccgcgg ggtgggtttg gtggatcggc ggcggggcta gctggtctga
    14101 cagcgggttg agtcaaatga ctcaattttg tggggagctg catcgagaca cttaaaattc
    14161 ccgagtcccc atgttagcgt cgggcttcat gagccgatcg tttgctcaac tgccagaagg
    14221 gctttggggt gccccgcgcc tggcgtcgat ggctggagat ggcacgcgcg tgggtgcgct
    14281 gttttcccgc ggaggaccga gatgacggtt gccggttcgc caactctgcg cacacccccc
    14341 gttgccccgg ggcggctgcc gggcctgggg catctgagtg cgttggctcg tgacccgctg
    14401 gggtacttgg cacggctgcg ctcagtggcc gatgtcgtca ccatctatct gggcccacgt
    14461 ccttcctatc tggtcacctc ccacgatctg gtacgagaca tgctggtctc ccagtccgag
    14521 tgcttcacgc gcggcgcggt attcgagcgc gccggcaagg cacttgggca agggttgctc
    14581 gtctccgacg gagagttcca ccgctgtcag cgacggttgc ttcagcccgc cttccaccat
    14641 cggcaaaccc cccgatatgc agaggtcatg gccgatgccg cgcagacatt gtcgcgggcg
    14701 tggcggccag gtgtgccgat cgaggtgacc cacgaaatac acacgatggc actggcggtg
    14761 gtctgccggg gcttgtttca caccgatctc ggcggatctg cggtgtcacg ggtcgagcgg
    14821 gcgctgaccg gtatcaacca aggggtcatc tggcagacgt tgtacccgtt cgactggctc
    14881 gcgcggttgc ccattccggt caaccgccgg ttccggagtg cgatcactga tgtccgcgac
    14941 cttgtcactc aactcatttc cgcttgtcga accaccggcg aaggccgtga gggtgtgctg
    15001 gcgatgctgc tacaagcccg cgacgaggag acggggcggc cgatgagtga cgatcaggtg
    15061 cgagacgaag tgctcacgct cttgctggcg gccaccgaga cgtcttccac cacattgtct
    15121 tggctcttct atgagctgga ccggcacccg gagatcgagc gcggggtcgc ccgcgagctc
    15181 gatgacaagc tggcaaacca gtccatcacc cacgacaacc tccgcgacct ggatctgatg
    15241 aaacgggtgg tcgatgagac gttgcgtctg cacacgccga actcgatcct gacgcgtcgg
    15301 gctgtccggg aggttcaact cggacagttc cggattccgg ccggggcgga ggtggccttc
    15361 agtcccaccg caattcaccg agatcccacg gtgtatgacg atcccctctc gttcaaaccg
    15421 gaccgctggc tatcggagaa ctcggcgcat gtgccgcggc atatgttcat tcccttcggc
    15481 atgggcaagc acaaatgcat tggcgactcg tttgccatca cggaaatgca cgtgacagct
    15541 gcgacggttc tgcgtgactg gcgcctgtcg cttgcgccga acgcacacgt ccgtgaacga
    15601 ccctgggcta ttgtgcaacc acacgggctg cgcatgatcc cgttcccgcg ccggtgatcg
    15661 gatttttcac ccaggaaact cgtcggatgc ggtgagggcg cgcgacgggg gaccgagtgg
    15721 cctggggggt catcgcggca gccgtccagt ggggaaatgg caatggcccc ttggggattg
    15781 aatttaagtt cctgcgaaca aattcaaaga ataagcgcga cacgcgagtt ggcgcgccgt
    15841 ttcaactggc ggaatacgta tactccgagc ccaatgctca gggaggctat gggttgagca
    15901 atggctcggt cgatggaatg tcgcgccgac agttcatggc caaactcgcg gcggcgagca
    15961 gcgccggcgc tctgatgtct ttggccggcc cggtgattga aaaggcttat ggggcagggc
    16021 cttgttccgg ccatttgacc gacatcgagc acattgtgtt gttgatgcag gagaatcgct
    16081 cattcgacca ctatttcggc acgctctccg gcgtgcgcgg gttcgacgac accaccgatc
    16141 cggcgatatt cgaccaaaag ggctgggacc cccggacgca gtcgatcgac ccggccggca
    16201 tcacgtcgcc attccgtttc gacaccactc ggggccccct gctcaacggt gagtgcgtca
    16261 atgacccggt cgaggggtgg gtcgcgatgc acaccgcctg gaacaacggg gccaacgaca
    16321 cctggctgcc gtcgcagtac tcgcagatac gccagggcaa catcccggcc tgcatgggct
    16381 actacacccg agcggacctc ccgatccact acatgctggc cgacactttc acgatctgcg
    16441 atgactacta ctgctcgatg ttgaccggga ccgcgcccaa ccgcctgtac tggttgagcg
    16501 cctggatcga cccggacggt accaacggtg ggccgctgct gaacgagccg aatttcctgc
    16561 cgctgcagcc gttcagctgg cgcatcatgc cggagaatct cgaggatgcc ggcattagtt
    16621 ggaaggtgta ccagaacaag tttttcgggc actacatcaa ttcgcctatc agcgacaacg
    16681 gcctggttca ggctttcaag caaaccgccg atccaaggtc gaatctcgct cgattcggca
    16741 tcgcccccac ctaccctcag gatttcgttc tcgacgtgaa agccaacagg ctgccgaagg
    16801 tttcctgggt ggtccccaac atcatccaat ccgagcatcc ggcactgccg gtgaacgtcg
    16861 gtgcggttgc gattgtgaac atattgcgga ctttgctgtc caatcccgcg gtgtgggaaa
    16921 agaccgcgtt gatcatcagc tatgacgaat gcggttcgtt cttcgatcac gtcacaccgc
    16981 ccacggcgcc gccgggaacg ccgggcgaat acgtcacggt gcccgacatc gacgcggtgt
    17041 ccggctccgg tggcatccgg gggccgatcg gtctgggcta tcgcgtgccg tgcatcgtca
    17101 tttcgcccta tagccgtggg ccgctggtgg tctccgacac cttcgaccac acctcgcagt
    17161 tgcgattgat cgagacacgg ttcggggtgc cggtgcccaa cctgacccct tggcgacgca
    17221 gtgtcaccga ggatatgacc tcggcgttca actttgctgt cccgccgaac ccatcgcgac
    17281 ccaagttgga tcctccgctg ctcaacgcgc tgcccaggct gccccaatgc gtccccaacg
    17341 cggtattggg atccttgggg ggagcggcgg tggccaaccc gtatcgggtg ccttacccgc
    17401 aggtgccgcc cacgcaggag accacgcccg cccgcggaac gcccagcggt ccctgctaac
    17461 ggccgaaggc gtcaccggcc acccggcggg ttgttgcggt aatcggcgcc ctgggcacta
    17521 ccggcgggag tcgtcgcggt cgggtgtgtg ccggcatggc ggtgctccgg attcgccgtc
    17581 gcgggccgaa agtgcgtgct aacttaccaa aggtgacgca ggtcaccact tttccgctag
    17641 tcgacgcgat cgtgtcgcgt cggggtggca gcctggacgg cgttgtcgtc atcgccgcac
    17701 agcatctgct ggagacgacg catgcgatgc tgcgctcgtt gtttcgggtc gggctcgacc
    17761 cccgcaacgt cgcggtgatc ggcaagtgtt actcgactca tctcggagtc gccgatgcca
    17821 tgcgagccga cggtgttcac gtcgatgagt tcagcgccgc ctatgcgccc cacgaatcct
    17881 tcgacaccga gtacacgcga catgtggaac ggttcttcgc ccaatcctgg gatcggcttg
    17941 cggctggccg agccggccga gtcgtgctgc tcgacgacgg tggctcgttg ctggccgccg
    18001 ctggtgccgc actcgacggc acggccaaca tcgtcgggat cgagcagacg tcggcgggct
    18061 acgccaagat cgccaactgc gcgcttgggt ttcccgtcgt caacatcgcc cgctcgtcgg
    18121 ccaagctcct ctacgagtcg ccgataatcg cgggcaacgt gacacgatgc gccttcgatc
    18181 gcatcgaggg cctcgaccgc ggtgacgcca tcctgatcac cggtgcggga gcgatcggca
    18241 gcgcgctggc cgaccagctg cgtccccgtc atgagcgggt ggatgtgtac gacacccgcg
    18301 tgggccaccc gggcccgatc gatctgaccc aggcgatcgg tgactacgac gtgatcatcg
    18361 gtgccaccgg agcgaccagc gtgcccaccg agttgcacga tctactgcgc cccggcgtgg
    18421 tgttgatgtc ggcgtcatcg tctgatcgcg agttctcggg cgccgcgttg cgccggcgtg
    18481 cgattccgga tcccaactgc catgccgacc tgcgcatcgc cgacggcaag ctcgatgcga
    18541 cattgctgaa ctcgggattt ccggtcaact tcgacggctc ggcaatgtgc ggtgacgagt
    18601 ccatgtcgct gaccatggcg ttgctggcgg cggcggtgct ctacgcggcc agcgcggaag
    18661 ccgccgatat cgactgcgat catccgcatc tcgggctgac cgaccagggc gacatcgtgc
    18721 agtcgtttct gaacatcgat gtcccgctgc aggctctcgg caggctgccg ttgctctcgg
    18781 tcggcgggta ccgtcgcatc gagctgcggt ccggcgacat cgtgttccgt caaggggagc
    18841 cggcctcaca cttctacgtc gtcgaatccg gcgaactcga agcgtttgtc gacggccagc
    18901 tggtgctgcg gctggtcgcc ggcgatcact tcggcgaaat cgctctgctc agcggctggc
    18961 ggcgggcggc cacggtgcgg gcgagccagc cctcagtgct gtggtcgctg gacgccgcgg
    19021 ccttcagcga ggtcctcaga gtggacgcca cgatgcgcga gcttgcgcac caggccattc
    19081 attcacgggt cagccgcgtg gtcggcgcac ccaagtcatc gagcgtctag cagacccgcg
    19141 gccctttggc gtcgatcgcc agcccgaagc ccgtccccgg accgctgccg atcagatctc
    19201 taccgctggc ccgtgaggtg ctcccggacc agcgcacaaa gccgccatcg gcccggcacg
    19261 cccttgagtt cgtgttcgcc gcgctcggcg aatctgtggc tcgagccggt gacgatgtca
    19321 cgcaccgtcg aggacaccag cacctcactg gagccggcca gcgcacagac ccgggcaccg
    19381 atgtgtacgg ccaggccggc gacgtcggcc ccccgcacct cgacctcgcc ggcatgaatc
    19441 cccacccgga cctcgatgcc gagcacggcg acggcgtcga cgacggcgtc cgcgcagttg
    19501 attgccgcac tcgggctgct gaacgtcgcg acgaacccgt cgcccgcggt attgacctcg
    19561 cgcccaccga accgctggat ctcgtggcgg accaggttgt cgtggttatc gagcaggtcg
    19621 cgccagcgca ggtcacccac ggtggctgcg cgctgggtcg agccgacgat gtcggtgaac
    19681 atgaccgtgg tcagtacccg ctcggtgacg aagccgcccc ggacgccggt gatgaactcc
    19741 tcgacctcgt cgagcaacgc ggcggtgtcg ccgacccaat acaaggaatc ggaaccggga
    19801 agctcgacca agcgcgaccc ggcaatgtgc tcggccagat agcggccgtg ctcgaccgga
    19861 acgaacttgg tgcccacccg atgcaggatc agcgtcggcg cggtgatgtg gggcagcgag
    19921 tcgcgcgcat ccgaggcttg aaccgcgttg atgaaggcgc gcgccgtgct gggcgaggcc
    19981 gcccggtttc cggccagatc ccaccagtcg cggaacgcgt cgtcatgggc cacgctgggc
    20041 gccatgatgc gcagcacgtc gaacccctgc tcgaccgcgt cgggatcggt tccgagggtg
    20101 aggaatggtt cggcggtgtt ggacctgatg cccagttcgt agtcgggcgc atgcagtgtc
    20161 cgcgcggagg cgttgatgag caccaggctg cgcacccgct cgggatagtc ggcggccagc
    20221 accagggcgg tcgtcgcggt gaacccggag gcaagaatcg tggcttcctg gcatccggcc
    20281 gcgtccatca ccgcaatcgc atcctcggcc cagaacctcg ggccgagcgc atccggcgac
    20341 gaaacccgcg atgacaggcc gacgccgcga tggtcgaacc ggatcaggcg ggaaaacgac
    20401 gccagacggc ggtgaaagcg gtacatcgac ggttcggaat cgatggtgtc gaccggaatc
    20461 gaggcccccg gtatgacgag caggtcgatc ggatgatccc cgatcacctg gtaggcgatg
    20521 tccaggtcgc cgcacctggc gtagcgagtc cggggagttc ggggcgcctg cgacacggct
    20581 acaacgtaat gatcggaatc agatagcggg cggcgtactc gcggaccgcg gcgtcatccg
    20641 aggtatcgag acgctcggtg ggaaacatga tgatgcccac ggcaacacgc agcaggatgt
    20701 cggcgatgtt ggcgaggtcg gcgtcgggag catcggcgcc gcagcgccgc agcgtgtggg
    20761 cgatgccgtc ggcgaattgg ccgatcggga agacgtggga gcgggaaaac atgccgaata
    20821 gctccggctc gctttcggct atccgcgagt acagcgggga atcctggatg agtcggaccc
    20881 cgagggtgaa cgcctcgatc accgcctcac gcgggttgtg gccgttggtg gcctggttca
    20941 gggcggcgaa gaacaactcc gcctcgcgcc gcacgacccg ttcgaacagc tcgtccttgg
    21001 tgggaaagcg tcggtagatg gtgctgcggc tgacaccggc ccgggtggcg acgtcttcga
    21061 tgttcgcccg ccggacaccg taggtctcga aaaccgcgcg tgcggtgtcc aggatggtgc
    21121 ggtcgagatc ggtgatcgac tcgactccgt cggtgctggt ctcggtgccc attctggact
    21181 gcatgataga tcggctccgc cctgcggatc cccccgaatg ccgcgttttc ccagatcact
    21241 gccccctgat cgggagcctg acgcggggca ccgctcattt gcggccgccc gccgcggtgg
    21301 ctagggtgac acaaagagac gaacttgtat cagtggttca ctagcgacac atggattcgt
    21361 caaggagggt ggatggcaac ggagctgacc gcgggcgtgg atttcgacac cggtgtccgg
    21421 gaggccctac ccatgccgat cgaccggccc gtcgacgacg agatcgtcgc gcagcggctg
    21481 ggcccgactt cgctgatctg gaaattctat ggagacgtgc gtactcaact cttcggattc
    21541 cagcgcgcgg ccggcaccga aaactgcatc gaacagctcg gtcagggagt cctcgatcat
    21601 tcggtggtct tcagcgacac cctgggccgg gccaagcgca ccggaccgcc cttgatgcgg
    21661 accgtgtatt ccgaggaccc ccatgggtgg ggtcgcacgg tgcgggattt ccacaagccg
    21721 atcaagggca ccatcggtga tggctctcgg taccacgcgt tgaatccgga gttgttctac
    21781 tgggcccacg ccacgttcgt cgaccaaatc ctctacaaca ccgacacgtt catccggagg
    21841 ctgtcccgcg cggaaaagga gcagatcttc gaggagagca agatctggta cggcctttac
    21901 ggcgtcagcg atcgaagtca gccgcaaacc tatgacgagt tcgtggccta ctgggacggc
    21961 atgctcgacc ggttcgtccc gcacaagacc gtgctctacg ggaccggcta tctacgcaaa
    22021 gggatccctg gcccccgcaa gctgcctgcg ctgatctgga ggatcctgtc tgcgcccctg
    22081 aacgcctacg cccggttggt gattgtcgga accctgccgc cgcagatgcg cgaggtgtgt
    22141 gacctcgatt ggaacgccaa gaaggagagg cgatttcagc gtttcgccgc cctcatacga
    22201 gggctgaatc cggtgctggg gcggctgccg gtcaggttga tctacttgcc atgggcggcg
    22261 caggcgtgga cccgctcggg ggttgacccg cgcaggctgc accgccgcgc cgtctcgaca
    22321 tgacggccgc cgcgaggacg gccctactgg ggccgggagg ctggatacgg cagcagcgcc
    22381 atttcgcggg cattcttgat cgcggtggcg atctgccgtt gttgttgcac ggtgagaccg
    22441 gtgacccgac gagagcggat cttgccgcga tcggagatga acgtgcgcaa ccgcgagatg
    22501 tccttgtagt cgacctcgct gaccccgagc gaatccagca ggttcttctt ggcgggcgtt
    22561 gccggggctg cgatggggcg ccgagtgcgt ctgggtttct ttttcatctg cggctaccag
    22621 ctcgccttgc gaacacccgg tagctgaccc gcatgggcca actcgcgcac tcgcacccgc
    22681 gacaatccga acttgcgcag gtggccgcgc ggacggccgt cgatggcgtc gcgattgcgc
    22741 agccgtaccg cactcgcgtc acgcggctga cggctcaggg cgcgttgtgc gtcgagccgc
    22801 tgctcgtagc tgctggtggg agattggatg atctgcttga gttcggcgcg ccgctgggcg
    22861 tagcgcgcga cgatgtctcg gcgcttgttg ttcttgacga tcttggattt cttggccatt
    22921 cagcgttcct cccggaatgg gacgtgcttg cgaatcaccg ggtcgtactt gctcagaatg
    22981 agccggtcgg ggtcgttgcg gcggttcttg cgggtgatgt aggtgtatcc ggttcccgcg
    23041 gtggagcgaa gcttgactgc cgggcgaatc tcgttgcgcg ccattagatc tgttcaccgg
    23101 cccgccggag ccgcgcgacc gtggcctcga tgccgtcgcg gtcgatgacc ttgatgccct
    23161 tggcgctgac ccgcagcttg atgcgacggt tctccgacgg caggtaatag gtcttgagct
    23221 ggatgttcgg tgaccaccgt cgtcggctcc ggcggtgcga atgcgacacc gtattgccga
    23281 aactcaccgt gcgaccggtg acttggcatc gtgcggacat gggcgcctcc tcagtgcacg
    23341 cttattgaaa atcattttcg acaaccccgt gtgacgcact gtatcgtgag tccggtctta
    23401 atgaaaatcg ttttcaataa cgatcgggag agctcggga
//
