LOCUS       NC_009636              27120 bp    DNA     circular CON 15-MAR-2024
DEFINITION  Sinorhizobium medicae WSM419, complete sequence.
ACCESSION   NC_009636
VERSION     NC_009636.1
KEYWORDS    RefSeq.
SOURCE      Sinorhizobium medicae WSM419 (Ensifer medicae WSM419)
  ORGANISM  Sinorhizobium medicae WSM419
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
REFERENCE   1  (bases 1 to 3781904)
  AUTHORS   Reeve,W., Chain,P., O'Hara,G., Ardley,J., Nandesena,K., Brau,L.,
            Tiwari,R., Malfatti,S., Kiss,H., Lapidus,A., Copeland,A., Nolan,M.,
            Land,M., Hauser,L., Chang,Y.J., Ivanova,N., Mavromatis,K.,
            Markowitz,V., Kyrpides,N., Gollagher,M., Yates,R., Dilworth,M. and
            Howieson,J.
  TITLE     Complete genome sequence of the Medicago microsymbiont Ensifer
            (Sinorhizobium) medicae strain WSM419
  JOURNAL   Stand Genomic Sci 2 (1), 77-86 (2010)
   PUBMED   21304680
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3781904)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Dalin,E., Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M.,
            Vergez,L., Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Reeve,W. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Sinorhizobium medicae WSM419 chromosome
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3781904)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Dalin,E., Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M.,
            Vergez,L., Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Reeve,W. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2007) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000017145.1-RS_2024_03_15
            Annotation Date                   :: 03/15/2024 03:53:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,520
            CDSs (total)                      :: 6,452
            Genes (coding)                    :: 6,144
            CDSs (with protein)               :: 6,144
            Genes (RNA)                       :: 68
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 308
            CDSs (without protein)            :: 308
            Pseudo Genes (ambiguous residues) :: 0 of 308
            Pseudo Genes (frameshifted)       :: 194 of 308
            Pseudo Genes (incomplete)         :: 203 of 308
            Pseudo Genes (internal stop)      :: 37 of 308
            Pseudo Genes (multiple problems)  :: 111 of 308
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2280219
            Orig. end                         :: 2307339
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000738.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4001622
            Source DNA and bacteria available from Wayne Reeve
            (reeve@murdoch.edu.au)
            Contacts: Wayne Reeve (reeve@murdoch.edu.au)
            Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LLNL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27120
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="6"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..27120
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27120
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17120](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..17120)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(787..2466)
                     /locus_tag="SMED_RS10980"
                     /old_locus_tag="Smed_2200"
     CDS             complement(787..2466)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010969825.1"
                     /locus_tag="SMED_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2200"
                     /product="alpha/beta-hydrolase family protein"
                     /protein_id="WP_011976330.1"
                     /transl_table=11
                     /translation="MEHVQQTDLPRPVPRRISNFLRSFSTSGLLIGVLFFAVSLTPSLI
                     PRPYLIQAVISGFSLAAGYAIGVFLRWLWSFFELPEPTVRRARTLKIAAAIVSIAAAVV
                     FLWQASHWQNTVRHIMGLEPIESAEPATLGLMAILVFAALVLLARLFRLTFRVLSRWLQ
                     YFLTRPVANALGGLVALALFWSAANGVIFKFALRAADSSFQQLDSLIDPEVAPPADPGK
                     TGSAASLVHWDELGRQGRQFIASGPTGAEIGAFFGIAAPEPVRVYVGLNSAETARERAK
                     LALEELKRAGGFERKSLIVIVPTGTGWIDPEALDTLEYLLHGDVASVAVQYSYLTSWLS
                     LLVEPSYGAEAADALFDEIYGHWTTLPKDRRPKLYLHGLSLGAMNSQGSVDLFDVISDP
                     FQGALWSGPPFQSTLWRSVTADRVPDSPAWLPRYRDSSAIRFTNQENALDIPGAHWGAM
                     RIVYLQYASDPVTFFDPHSFYREPDWMRSPRGPDVSPALSWFPLVTGLQLLADMALATT
                     SPMGYGHVYAPEHYIDAWMAVTDPPGITAADVARLKAQFSAR"
     misc_feature    complement(2583..2595)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    2616..2632
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.91"
                     /tool="antismash"
     gene            2664..3947
                     /locus_tag="SMED_RS10985"
                     /old_locus_tag="Smed_2201"
     CDS             2664..3947
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (95-266). E-value:
                     2.3e-08. Score: 25.5. Matches aSDomain:
                     nrpspksdomains_SMED_RS10985_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017270444.1"
                     /locus_tag="SMED_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2201"
                     /product="cystathionine gamma-synthase family protein"
                     /protein_id="WP_011976331.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-06, bitscore:
                     25.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPHPSKTHIGNHKLHPETLMLNYGYDPELSEGAVKPPIFLTST
                     FVFHSAEEGRDFFDFVSGRREPPEGVGAGLVYSRFNHPNSEIVEDRLAIYERAEAGALF
                     SSGMSAIATTLLAFVRPGDSILHSQPLYGGTETLLAKTFLNLGISATGFADGVDEAAVS
                     AAAEEAMSKGRVSMILIETPANPTNSLVDVAMIRRIAERIEERQAHRPIVACDNTLLGP
                     VFQHPIEHGADLSLYSLTKYVGGHSDLIAGAVLGSKALIRQVKALRGSIGTQLDPHSCW
                     MIGRSLETLSVRMEKANENARIVAEFLRDHPKVEHIHYLPFHDPEAPVGRVFAAQCTGA
                     GSTFSFDIAGGQEAAFRFLNALQIFKLAVSLGGTESLASHPAAMTHSGVPIEVRARIGV
                     LESTIRLSIGIEHPDDLVADVANALTTI"
     aSDomain        2949..3461
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMED_RS10985_Aminotran_1_2.1"
                     /evalue="2.30E-08"
                     /label="SMED_RS10985_Aminotran_1_2.1"
                     /locus_tag="SMED_RS10985"
                     /protein_end="266"
                     /protein_start="95"
                     /score="25.5"
                     /tool="antismash"
                     /translation="ERAEAGALFSSGMSAIATTLLAFVRPGDSILHSQPLYGGTETLLA
                     KTFLNLGISATGFADGVDEAAVSAAAEEAMSKGRVSMILIETPANPTNSLVDVAMIRRI
                     AERIEERQAHRPIVACDNTLLGPVFQHPIEHGADLSLYSLTKYVGGHSDLIAGAVLGSK
                     ALIRQVKA"
     gene            complement(4068..4364)
                     /locus_tag="SMED_RS10990"
                     /old_locus_tag="Smed_2202"
     CDS             complement(4068..4364)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976332.1"
                     /locus_tag="SMED_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2202"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_011976332.1"
                     /transl_table=11
                     /translation="MSKVADSIRRGLNEALACAEGSADANAFRVHVPERMDVKAIRTKL
                     EMTQEEFAGRFGFSVNTLRHWEQGSRQPEGPTRAYLLVIDRAPKAVQKALQAA"
     gene            complement(4361..4513)
                     /locus_tag="SMED_RS32130"
     CDS             complement(4361..4513)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018012666.1"
                     /locus_tag="SMED_RS32130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_018012666.1"
                     /transl_table=11
                     /translation="MVYFYHDADMPLFALTACAKNMRADLGQQDRNDFRQLTTMLVDAF
                     KRRKR"
     gene            complement(4816..5175)
                     /locus_tag="SMED_RS10995"
                     /old_locus_tag="Smed_2204"
     CDS             complement(4816..5175)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018012667.1"
                     /locus_tag="SMED_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2204"
                     /product="VOC family protein"
                     /protein_id="WP_011976333.1"
                     /transl_table=11
                     /translation="MKVRRIMPNFQVSDLLEADRFYRALLGLEIVMNHGWIVTYAADGS
                     SAMPQVSFATEGGSGTPVPALSIEVDDVDEAYRRAKAAGTEIVYDITDEDWGVRRFFLR
                     DPFGNIVNVLSHAES"
     gene            complement(5172..5780)
                     /locus_tag="SMED_RS11000"
                     /old_locus_tag="Smed_2205"
     CDS             complement(5172..5780)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976334.1"
                     /locus_tag="SMED_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2205"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_011976334.1"
                     /transl_table=11
                     /translation="MAATQNTRERIVSAAARLFYAEGIRAVSVDAVAEAAGLTKRTLYY
                     HFKSKDELIAAYLEERDQPNLKLFQKWFSETDGDAASKIKAIFLNLARAARHPKWKGCG
                     FLRTSAELANMPGHPAIRIAAAHKRKFEDWLRQSFETEGIAEAARLARQMLLLLDGSFA
                     VVLLHRDPSYMETAGEAAATLVKLALSEPSVQQPAGRGK"
     misc_feature    complement(5861..5881)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.49"
                     /tool="antismash"
     gene            5864..6655
                     /locus_tag="SMED_RS11005"
                     /old_locus_tag="Smed_2206"
     CDS             5864..6655
                     /NRPS_PKS="Domain: ECH (7-254). E-value: 4.8e-65. Score:
                     211.2. Matches aSDomain: nrpspksdomains_SMED_RS11005_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018095567.1"
                     /locus_tag="SMED_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2206"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_011976335.1"
                     /transl_table=11
                     /translation="MSDTVLLKISGGTALLTLNRPERLNALNYELIDRLLTLLDRLEVD
                     AKVHAVILTGAGDRAFSAGGDIHEFSHSVAEGVNAAIRDFVRRGQQLTSRLEAFPKPVI
                     AAVNGIAYGGGCEITEAVHLAIASDRSRFAKPEIKLGMPPTFGGTQRLPRLAGRKRALE
                     LLLTGDAFSAERALEMGLVNAVVPHADLIETARALAARIISHSPVATAAIISAVTRGLN
                     MAIGEGLLCESEQFARMVPTHDLNEGLAAWKERREPRYAGR"
     misc_feature    5876..5890
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.34"
                     /tool="antismash"
     aSDomain        5885..6625
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMED_RS11005_ECH.1"
                     /evalue="4.80E-65"
                     /label="SMED_RS11005_ECH.1"
                     /locus_tag="SMED_RS11005"
                     /protein_end="254"
                     /protein_start="7"
                     /score="211.2"
                     /tool="antismash"
                     /translation="KISGGTALLTLNRPERLNALNYELIDRLLTLLDRLEVDAKVHAVI
                     LTGAGDRAFSAGGDIHEFSHSVAEGVNAAIRDFVRRGQQLTSRLEAFPKPVIAAVNGIA
                     YGGGCEITEAVHLAIASDRSRFAKPEIKLGMPPTFGGTQRLPRLAGRKRALELLLTGDA
                     FSAERALEMGLVNAVVPHADLIETARALAARIISHSPVATAAIISAVTRGLNMAIGEGL
                     LCESEQFARMVPTHDLNEGLAAWKE"
     gene            complement(6669..7148)
                     /locus_tag="SMED_RS11010"
                     /old_locus_tag="Smed_2207"
     CDS             complement(6669..7148)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976336.1"
                     /locus_tag="SMED_RS11010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2207"
                     /product="anthrone oxygenase family protein"
                     /protein_id="WP_011976336.1"
                     /transl_table=11
                     /translation="MVTLVPVLAFAAVIGSGLMAGLFFVFSVCIMQALSRLPPEQGVAV
                     MNAINVVIQNPLFLIAFMGTALLGLVLLVMAVIWGGQGSYFLAAGGLVYLIGTLAVTIA
                     VNVPLNEALAAAPAGQGATELWQQRYLTEWVRWNHVRSFASTAALALFVLGFART"
     gene            complement(7198..8511)
                     /locus_tag="SMED_RS11015"
                     /old_locus_tag="Smed_2208"
     CDS             complement(7198..8511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976337.1"
                     /locus_tag="SMED_RS11015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2208"
                     /product="glucoamylase family protein"
                     /protein_id="WP_011976337.1"
                     /transl_table=11
                     /translation="MSLHSRTSDIACIDGLQRAAFEYFLRYSDMRSGLVADTSRAGSPS
                     SIAATGFGLAAYPVAVERGWIARSDAAWRVLTTLRFFAASRQGSDASATGYRGFYYHFL
                     DMRTGDRVWRSELSTIDTSLLLAGALTAAAYFSGRSEEESELRRLAALLYERADWYWAL
                     NGGDTVTMGWRPPGRFLKHRWRGHSEALLLYVLALGSPTRPIMPPNYEAYTAAHEWLEL
                     DGAAHLHAAALFVHLFPQAWIDFRSIRDKGMRDRATDYFDNTRRAIRLQRAHAEENPHG
                     FAGYCRDLWGFSACHAPKGWFRLRDGRRQKLLGYEARGAPFGADDGTLVPWAPLAGLPF
                     EPDACLGSLFHLMSRYPALVKEERLPGGFNPSLPGDGPEGWMDDRLVGLDQGLVVMMIE
                     NWRSGLVWELTRGIPAFRQGLSRAGFAGGWLSSTLLQV"
     gene            8743..9537
                     /locus_tag="SMED_RS11020"
                     /old_locus_tag="Smed_2209"
     CDS             8743..9537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013844664.1"
                     /locus_tag="SMED_RS11020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2209"
                     /product="DUF1194 domain-containing protein"
                     /protein_id="WP_011976338.1"
                     /transl_table=11
                     /translation="MLGTMALILALSGAPIQSAAISADVDVELLLAVDMSGSMDMEEAR
                     VQRSGYLQALRHPDFINAVQGGLLGRIAIGYFEWAGLVNEASVVSWQVIESSADAEAFA
                     GKLEARPIGTRRGTSISNAILFGSDLIDSNAYSGTRRVIDISGDGPNNTGPPVTPARND
                     ALSRGIIINGLAILIRPSVSTGPLDRYYAECVIGGPGSFVLPVHEPEDFAVAIRQKLIL
                     EVSGREPDPALRLAAGENAADCMIGEKLRPGFLDRVYPELDR"
     gene            complement(9644..9865)
                     /locus_tag="SMED_RS11025"
                     /old_locus_tag="Smed_2210"
     CDS             complement(9644..9865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003534187.1"
                     /locus_tag="SMED_RS11025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2210"
                     /product="hypothetical protein"
                     /protein_id="WP_011976339.1"
                     /transl_table=11
                     /translation="MTNHSSSLTDTEVELASIARMLSHIRESARALEAQAVEYCIDMAL
                     QAVANELRDRGELVIAAAGFDNRTTLLQ"
     gene            complement(10001..11215)
                     /locus_tag="SMED_RS11030"
                     /old_locus_tag="Smed_2211"
     CDS             complement(10001..11215)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976340.1"
                     /locus_tag="SMED_RS11030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2211"
                     /product="YcaO-like family protein"
                     /protein_id="WP_011976340.1"
                     /sec_met_domain="YcaO (E-value: 3.4e-79, bitscore: 264.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGFAVGSPADTRNAYSDRVLSPEETFDRVRPLLSRFGVTRIARH
                     TGLDRIGLPVWCAYTPNARSIAVAQGKGLTDPEAKVSAVMEALERAVACEPAVGTMVAT
                     ARTLRASGRTVELLPCLIAAGQQDIGPDEELAWALGSDLISGREILVPLAAALLDRTLH
                     SRFWMSSDGLASGNVVEEAILHGLLERIERDAHVLWGISGREHRYGCCVAPESLGDAAL
                     NGLVERIGAAGLDLRLFEITSDIGIPCFLALLGPPDIATRGGGRFVEVTSGCGAHVFPA
                     RAAIRAVTEAAQSRLTFISGARDDVFPETFNRPLPELTRQAFLAEPSRRAIASPQVGGS
                     LEALLRHTVDHLTSAGVQSAIALRLSANALPFSVVKIFVPKLENPDGDRARRFGPRALS
                     KALAS"
     gene            complement(11212..11427)
                     /locus_tag="SMED_RS11035"
                     /old_locus_tag="Smed_2212"
     CDS             complement(11212..11427)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018095572.1"
                     /locus_tag="SMED_RS11035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2212"
                     /product="hypothetical protein"
                     /protein_id="WP_024310816.1"
                     /transl_table=11
                     /translation="MAEVVVIGIAGEQGLWLADLKNGTVRPLDQVSGDLATANKLRLQG
                     GTIVKNVDLAVAVSSADKVFSGHFDG"
     gene            complement(11445..13283)
                     /locus_tag="SMED_RS11040"
                     /old_locus_tag="Smed_2213"
     CDS             complement(11445..13283)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018095573.1"
                     /locus_tag="SMED_RS11040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2213"
                     /product="adenylate cyclase"
                     /protein_id="WP_011976342.1"
                     /transl_table=11
                     /translation="MAVPHFHLQTFGELRLVDSGGVVVACPERGLLILAYLSISGQRTV
                     SREKLSMLIWPEREKSVAFKNLRSTLWRMRHLAANSGPLTSATEIDVTLGEIACDAAGF
                     EALGSSEEAFRAGLSLWRDTFLAGADVPPGRYADWVGEQRSVFTQKLRAALLAGGERFA
                     DRSMLRTACMHLLELDPADTAVRAILERLTGVGLVIGKGSPDGAWLRQGAFAGESPRAP
                     ARDAITPPVAPAPRVALLPPAAFGSDPMLHAVSMAVVEDITIGLCALRSMSVVAPYTAE
                     RIRDAADKAAFLEKHAVTYALDCRMSDQGLFTQLIFLPSDAIVWAERFSISPVGLLQQR
                     QEIAFHVASAVAEQVETGRIGHLDYVTNPDAYYAYLAGLRNLSNVGLPEIRRARRDFKT
                     ALRHKPDFAPALSGIARTYAIEWVLTARGDQELLTVAERHAKEAIESDEELPGAHREFG
                     VVRLYQGDLDGSLAALDRAENLSPHYADVLYSHADTLVHASRPREALDKLGKALSLNPL
                     APDMYFWSAAGASYFLEEYEDAIGYVQKMKDKSPGDRLLAASWAMLGDQKKARSYKVKA
                     LRANPTFDVDKWLAVVPMKEQWQKDLYREGLKRAGF"
     misc_feature    13454..13467
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.78"
                     /tool="antismash"
     misc_feature    13464..13480
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.12"
                     /tool="antismash"
     misc_feature    13563..13578
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     gene            13650..14441
                     /gene="aac(3)-IV"
                     /locus_tag="SMED_RS11045"
                     /old_locus_tag="Smed_2214"
     CDS             13650..14441
                     /codon_start=1
                     /gene="aac_3_-IV"
                     /gene_functions="resistance (resist) AAC3"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011976343.1"
                     /locus_tag="SMED_RS11045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2214"
                     /product="AAC(3)-IV family aminoglycoside
                     N-acetyltransferase"
                     /protein_id="WP_011976343.1"
                     /transl_table=11
                     /translation="MTQREWRISELVNQLLTLGVKPGGVLVVHSSFRSVRPVEGGPAGM
                     IAALRTAIGPEGTLVMPSWSGLDDEPFEPATTSATSDLGILADTFWRLEGVVRSDHPFA
                     FAAAGPLAARITSDPLPLPPHCPPSPIGRIHELDGQVILLGVGHDSNTTLHLAELMSKV
                     PYGVPRHCTIVENGSRVRIAYLENDHCCQNFSLADVWLRRNGLQKEGQIGNAHARLVRS
                     RDIVKIAMEQLAHDPLVFLHPAEVACEECDAARQSIGYGRS"
     gene            complement(14426..14757)
                     /locus_tag="SMED_RS11050"
                     /old_locus_tag="Smed_2215"
                     /pseudo=""
     CDS             complement(14426..14757)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007787770.1"
                     /locus_tag="SMED_RS11050"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2215"
                     /product="helix-turn-helix transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRWKKPTKEEVLENRRDLANRARSGELRLPHAVAEIRKGFGMTQ
                     EEFAKMLALTRRQVAEIEAGTANPTLETLEKMAVYSALGWVSCRGR"
     misc_feature    complement(14989..15003)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     tRNA            complement(15013..15088)
                     /anticodon=(pos:complement(2295272..2295274),aa:Ile,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="SMED_RS11055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Smed_R0035"
                     /product="tRNA-Ile"
     gene            complement(15013..15088)
                     /locus_tag="SMED_RS11055"
                     /old_locus_tag="Smed_R0035"
     gene            15237..16031
                     /locus_tag="SMED_RS11060"
                     /old_locus_tag="Smed_2216"
     CDS             15237..16031
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015007844.1"
                     /locus_tag="SMED_RS11060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2216"
                     /product="SIMPL domain-containing protein"
                     /protein_id="WP_011976345.1"
                     /transl_table=11
                     /translation="MSSTRIARTVHVAAVAAAFAGAFAAAAAAQDSAAGKDGKGDGKGR
                     PDAVRGRQAVIKVSGEGRSTTAPDMAVLQLSVVKDAKTAREALDANNKAMADVLSALKQ
                     AGIAERDLQTSGFSINPQYHYPQNNDGGNRPPELVGYQVVNGVGVRVRDLGQLGEILDK
                     SVSLGVNQGGGIEFTNDKPEAVITEARKAAVADAINKARVLAEAAGVSLGRLIEISEQP
                     SRPEPIPVVRSMAKEFAADSVPIATGENAYNVNVNVTFAIDQ"
     gene            complement(16224..16577)
                     /locus_tag="SMED_RS11065"
                     /old_locus_tag="Smed_2217"
     CDS             complement(16224..16577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018095609.1"
                     /locus_tag="SMED_RS11065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2217"
                     /product="hypothetical protein"
                     /protein_id="WP_011976346.1"
                     /transl_table=11
                     /translation="MKKFLVNAAIAAVIGLTGLVSTASAQSLTLEIGPGGVQYRDYDRH
                     DDWRGRGHYDRRDRRGRCAPGLAVEKARDRGLRRAYVADVTGRRVVVEGRRRGHRQAIV
                     FANARGCPVIGRW"
     gene            complement(16716..17120)
                     /locus_tag="SMED_RS11070"
                     /old_locus_tag="Smed_2218"
     CDS             complement(16716..17120)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF07366"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003537547.1"
                     /locus_tag="SMED_RS11070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2218"
                     /product="ketosteroid isomerase-related protein"
                     /protein_id="WP_011976347.1"
                     /sec_met_domain="PF07366 (E-value: 2.8e-12, bitscore: 44.3,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAQTIASRFMEALNDRDFDALSRLVDEDVAFDSLSGERTLGAG
                     SLRSWMMNYLRHFDESLSDIVLMRDAAGQRVAADTTARGTYRETLAGFPDASGQAYSIA
                     SVFVFEIEDGLITRLSQYRNIRLFERELAG"
     gene            complement(17214..17636)
                     /locus_tag="SMED_RS11075"
                     /old_locus_tag="Smed_2219"
     CDS             complement(17214..17636)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003537545.1"
                     /locus_tag="SMED_RS11075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2219"
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="WP_011976348.1"
                     /transl_table=11
                     /translation="MAQTVITMSTTGQGLYEFTAEAGEFVRATGVAEGLLTVFVRHTSA
                     SLIIQENADPDVKRDLGAFFHRLVPPSSDPSMDWIVHRMEGPDDMPAHIKSALTQVSLG
                     VPIMKGRLALGTWQGLYLFEHRDRPHRREIVLHIGS"
     gene            complement(17672..18025)
                     /locus_tag="SMED_RS11080"
                     /old_locus_tag="Smed_2220"
     CDS             complement(17672..18025)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018236660.1"
                     /locus_tag="SMED_RS11080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2220"
                     /product="DUF1428 family protein"
                     /protein_id="WP_011976349.1"
                     /transl_table=11
                     /translation="MAYVDGFIVAVPTANLEAYKKMASEAGAVWKEHGALNYVECIGDD
                     VPRGELTSFPRAVQATDDETVVFSWIVYRSRQDRDAIVAKVMADPRLQGDAWKDVFDGK
                     RLIYGGFEAFLEL"
     gene            complement(18139..18708)
                     /locus_tag="SMED_RS11085"
                     /old_locus_tag="Smed_2221"
     CDS             complement(18139..18708)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003537532.1"
                     /locus_tag="SMED_RS11085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2221"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_011976350.1"
                     /transl_table=11
                     /translation="MRCVFVVVLLLLAGCGTVPRETRNACAVFEQRDNLFNNWRRAAYA
                     AEREYGVPVPVLMATVYTESGFRHNAKPPRTKLLGFIPWTRISSAYGYSQALDGTWARY
                     QAETGRWTARRSDFGDAIRFIAWYHNQSHKRNGIALNDTYRLYIAYYHGHSGYARGNWS
                     ATAKAGAKRASGMAAVYARQLRGCNS"
     gene            complement(18933..19226)
                     /locus_tag="SMED_RS11090"
                     /old_locus_tag="Smed_2222"
     CDS             complement(18933..19226)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014329069.1"
                     /locus_tag="SMED_RS11090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2222"
                     /product="GYD domain-containing protein"
                     /protein_id="WP_011976351.1"
                     /transl_table=11
                     /translation="MTTYVVLLNWTEQGIRNVRESPKRLDAAKKVLEDMGGSFKDVYLT
                     MGEHDLVAICEAPDDAVAARFALTLGMNGNVRTRTLKAFPEAAYRELIGTLG"
     misc_feature    19428..19445
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(19497..21551)
                     /gene="rpoD"
                     /locus_tag="SMED_RS11095"
                     /old_locus_tag="Smed_2223"
     CDS             complement(19497..21551)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003494761.1"
                     /locus_tag="SMED_RS11095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2223"
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="WP_011976352.1"
                     /transl_table=11
                     /translation="MATKVKENEEADVEREGAPDGPLLDLSDDAVKKMIKAAKKRGYVT
                     MDELNSVLPSEEVTSEQIEDTMSMLSDMGINVIEDEEAEEAGGSDDDDSSDDAESEGGE
                     LAPASGTALATSKKKEPTDRTDDPVRMYLREMGSVELLSREGEIAIAKRIEAGRETMIA
                     GLCESPLTFQALIIWRDELNEGQTLLREIIDLETTYSGPEAKAAPQFQSPEKIEADRKA
                     AEEKEKVRKTRAAANDDDITNVGGEGQPAEEEEDDDDESNLSLAAMEAELRPQVMETLD
                     VIAETYKKLRKLQDQQVEARLAATGTLSPAQERRYKELKDELIKAVKSLSLNQNRIDAL
                     VEQLYDISKRLTQNEGRLLRLAESYGVKREAFLEQYSGAELDPNWMKSISNLAGKGWKE
                     FARAENQTIRDIRQEIQNLATETGISIAEFRRIVSMVQKGEREARIAKKEMVEANLRLV
                     ISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQ
                     ARTIRIPVHMIETINKIVRTSRQMLHEIGREPTPEELAEKLAMPLEKVRKVLKIAKEPI
                     SLETPVGDEEDSHLGDFIEDKNALLPIDAAIQANLRETTTRVLASLTPREERVLRMRFG
                     IGMNTDHTLEEVGQQFSVTRERIRQIEAKALRKLKHPSRSRKLRSFLDS"
     gene            complement(21641..21889)
                     /locus_tag="SMED_RS11100"
     CDS             complement(21641..21889)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMED_RS11100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162142224.1"
                     /transl_table=11
                     /translation="MYSRKSRTIAFFADLGGFSLETLDGIKNSGNHHFEQKWRHGTADR
                     KSCQGRFSGRTVEACPFTAIAVVVNQELNIIPLRQGK"
     gene            complement(21999..23033)
                     /gene="tdh"
                     /locus_tag="SMED_RS11105"
                     /old_locus_tag="Smed_2224"
     CDS             complement(21999..23033)
                     /EC_number="1.1.1.103"
                     /GO_function="GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tdh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010969852.1"
                     /locus_tag="SMED_RS11105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2224"
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="WP_011976353.1"
                     /sec_met_domain="ADH_N (E-value: 8.1e-32, bitscore: 107.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.2e-24, bitscore:
                     82.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNMMRALVKTRPEVGLWMERVPVPEVGPNDVLIRVRKSAICGTD
                     VHIWNWDQWAQKTIPVPMVVGHEFMGEIVEVGPAVTKHHVGERVSGEGHIVCGKCRNCR
                     AGRGHLCRNTLGVGVNRPGSFAEFVCLPEYNVVSIPDDVPDEIAAIFDPFGNAVHTALS
                     FDLVGEDVLVTGAGPIGIMGALVAKRCGARKVVITDINPVRLDLARKVGIDYVVDASKE
                     NLADVMRVIGMTEGFDVGLEMSGAAPAFRDMIDKMNNGGKIAILGIAPAGFEIDWNKVI
                     FKMLNLKGIYGREMFETWYKMIAFVQGGLDLSQIITHRIGIDEFGDGFEAMRSGNSGKV
                     VMDW"
     gene            complement(23074..24261)
                     /locus_tag="SMED_RS11110"
                     /old_locus_tag="Smed_2225"
     CDS             complement(23074..24261)
                     /EC_number="2.3.1.29"
                     /GO_function="GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (42-383). E-value:
                     5.1e-72. Score: 234.9. Matches aSDomain:
                     nrpspksdomains_SMED_RS11110_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007790104.1"
                     /locus_tag="SMED_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2225"
                     /product="glycine C-acetyltransferase"
                     /protein_id="WP_011976354.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.9e-70, bitscore:
                     234.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKAFLSHLSSELEGLKQAGLYKSERVITSKQSGEIEVASGQRVL
                     NFCANNYLGLAGNEELADAAKKALDRYGYGMASVRFICGTQEEHKELEARISSFLGMED
                     TILYSSCFDANGGLFETLLGEDDAIISDALNHASIIDGVRLSKAKRFRYANNDMAALEE
                     ELKKAEGSRFKMIATDGVFSMDGIIANLAGVCDLAEKYGAMVMVDDSHAVGFVGRHGRG
                     SAEHCGVEGRVDIITGTLGKALGGASGGYTSAKAELVEWLRQRSRPYLFSNTLAPVIAA
                     ASLKVFELIENGDALRERLSANAALFRAEMSRLGFTLAGEGHPIIPVMLGDAALAQEMA
                     ARMLEKGVYVIGFSFPVVPKGQARIRTQMSAAHSEADIRRAIAVFEEVGRELNVI"
     aSDomain        complement(23113..24135)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMED_RS11110_Aminotran_1_2.1"
                     /evalue="5.10E-72"
                     /label="SMED_RS11110_Aminotran_1_2.1"
                     /locus_tag="SMED_RS11110"
                     /protein_end="383"
                     /protein_start="42"
                     /score="234.9"
                     /tool="antismash"
                     /translation="RVLNFCANNYLGLAGNEELADAAKKALDRYGYGMASVRFICGTQE
                     EHKELEARISSFLGMEDTILYSSCFDANGGLFETLLGEDDAIISDALNHASIIDGVRLS
                     KAKRFRYANNDMAALEEELKKAEGSRFKMIATDGVFSMDGIIANLAGVCDLAEKYGAMV
                     MVDDSHAVGFVGRHGRGSAEHCGVEGRVDIITGTLGKALGGASGGYTSAKAELVEWLRQ
                     RSRPYLFSNTLAPVIAAASLKVFELIENGDALRERLSANAALFRAEMSRLGFTLAGEGH
                     PIIPVMLGDAALAQEMAARMLEKGVYVIGFSFPVVPKGQARIRTQMSAAHSEADIRRAI
                     A"
     gene            complement(24483..26333)
                     /gene="recQ"
                     /locus_tag="SMED_RS11115"
                     /old_locus_tag="Smed_2226"
     CDS             complement(24483..26333)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013844737.1"
                     /locus_tag="SMED_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_2226"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_024324107.1"
                     /transl_table=11
                     /translation="MPESHSTACLFETEGVRNPLDLLKRIYGYSTFRGQQQEVIEHVVA
                     GGDAVVLFPTGAGKSLCFQIPALCRGGVGVVVSPLIALMRDQVEALKQLGVRAAALNSS
                     LTREEAIAVRRSLSTGTLDLIYVTPERAVTDGFAEMIAGAEIALFAIDEAHCVSQWGHD
                     FRPEYRGLGCLAERFPNVPRIALTATADPHTRADLIERLALGAARVFTSSFDRPNIAYE
                     IVERDQPRQQLLRFLSRFKDASGIVYCLSRAKVEDTAEWLNTQGIRALPYHAGMDRALR
                     DAHQDAFLKEENLCLVATVAFGMGIDKPDVRYVAHLDLPGSVEAYYQETGRAGRDGLPS
                     EVWMAYGMADVIQRRRMIDEGGAPEEVKRIERAKLNSLLAICETAGCRRQAVLAHFGEA
                     HPGGCGHCDTCLKPVETWDGTEAAIKALAAVYRTGERFGTGHLIDVLMGSVNEKTERFG
                     HVDMPVFGAGKDLPARTWQSIFRQLLAAGLISVDHGAFGALKLEPEARSVFRRERQVLF
                     RKDRPSSGKAARGQKATRERSDLAGSDLELFERLRSERLTIAREMDVPPYVVFPDATLI
                     ALAKRRPRDFDDLLGVPGIGETKRERYGQAFLAVIEAFEG"
     misc_feature    complement(26299..26314)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
ORIGIN
        1 cgcaccgcgt gaaggcgctg gaggcgcaat tcaaccggaa actcttcacg cgcaacaagg
       61 gcgggaccct cccgacggct gccggtctgc ggtttctcga ctacgccaaa gctttgcaaa
      121 atcagtggca tgaagcgacg cgcgcagtgg cgagcgcagg cgccctcgag cgatcgatgc
      181 ggcttggaat tcagcacgat ctggccgaga ccattgcagg ccgatgggtg gctgcgatcc
      241 gccgcgatct gccgacgacc gagatctata tggaagcgga ttattcgaac cagatgaacc
      301 gcgatctcgc cgccggagag ctcgatctcg cagtgctcta cacgccgcac ttcctgcccg
      361 atcttcacta tgaacggatc ggcgaactgc attacgtgct cgtcagcacc gatacgcacg
      421 acttggccgg cgtgaggccc gaaacctaca tccgatcaag ctactcgccg gcctttgatc
      481 gtgcgcaccg cctggcactt ccgcaccttt cggcggctac tctttcagcc ggccagaaca
      541 tggcggtgat ggacctgttg cgcacgctcg gcggcgcggc ctatgtgacg caggcgaccg
      601 ccgaccagat ctccgaccgc gttgccgtcg tggccgatgc gccggtcatc ccgcagaccg
      661 tttacgccgc aacgagcctg cgcacccgcc acgcccacca gcaccgcaag atcatcggcg
      721 cgatggaggg cctgttggtg gagttgtaaa cgcatccacc gctaccgccc atcggtcctc
      781 gcccgatcaa cgcgcggaga attgcgcttt cagccgcgcc acatccgccg ccgtaatccc
      841 cggcggatcg gtgaccgcca tccaggcgtc aatgtagtgt tccggggcgt agacgtgacc
      901 gtagcccatc ggagaggtcg tcgccaacgc catgtcggcc agcagttgca gaccggtgac
      961 caagggaaac cagctcagcg ccggtgagac gtccggccct cgcggcgacc tcatccagtc
     1021 cggctcgcga taaaaggaat ggggatcgaa gaacgtcacc gggtcgctgg catattgcag
     1081 gtagacgatc cgcatcgcgc cccaatgcgc gccggggata tcgagggcat tctcctggtt
     1141 ggtgaagcgg atggcggagc tgtcgcggta gcgcggcagc caggcaggtg agtccggtac
     1201 ccggtccgcc gtcaccgaac gccacaaggt gctctggaac ggcggcccgc tccagagcgc
     1261 gccctgaaag ggatcgctga tgacgtcgaa gagatcgacc gacccctgcg aattcatcgc
     1321 cccgaggctc agaccgtgga gatagagctt gggccgccga tccttgggca gcgtcgtcca
     1381 gtgcccgtag atctcgtcga agagggcgtc ggccgcttcg gcgccgtaac tcggctcgac
     1441 cagaagcgac agccagctgg tgagatagga gtactgtacg gccacgctcg cgacatctcc
     1501 gtgaagcaga tattcgaggg tgtcgagcgc ctccggatca atccagccgg tgccggtcgg
     1561 cacgatgacg atcagagatt tgcgttcgaa gccgccggcg cgtttcaact cctcgagcgc
     1621 aagcttcgcc ctttcccgcg ccgtttcggc agagttcagt cccacataaa cccggacggg
     1681 ttccggcgcc gcgatgccga agaacgcccc gatttcggcg ccggtcggcc cggaggctat
     1741 gaactgccgc ccttgccgtc caagctcgtc ccagtgcaca agcgatgcgg cgctgcctgt
     1801 cttgccggga tccgcaggcg gtgcgacctc aggatcgatg agcgaatcca gttgctggaa
     1861 ggaactgtcc gcagcgcgaa gcgcgaactt gaagatcaca ccgttcgccg cagaccagaa
     1921 caaggcgagc gccacgagcc cgccgagcgc gttggcaacc ggccgcgtga ggaaatattg
     1981 cagccatcgt gaaagcacgc gaaaggtcag ccggaatagc cgtgccagca ggaccagggc
     2041 ggcgaatacg agaatggcca tgaggccgag agtggcgggc tctgcgcttt cgatcggctc
     2101 caggcccata atgtgccgca cggtgttttg ccaatgcgaa gcctgccata ggaatacgac
     2161 ggcggccgca atcgaaacga tggcggcggc gatcttcagc gtacgtgcac gccttaccgt
     2221 cggttcggga agctcgaaga aggaccagag ccagcgcagg aacacgccga tcgcgtagcc
     2281 cgccgcgaga gagaagcccg agatcaccgc ctgaataagg tagggccgcg gtatgagact
     2341 tggcgtcagc gaaacggcaa agaagagaac gcctatgagg aggccgcttg tggaaaacga
     2401 acgcaagaag ttggagatgc gacggggcac cggtcttggc aggtccgtct gctgaacatg
     2461 ttccatggcg actccacttc gcacgccggg caatgtcgcc ttccgccgac gcgcagtcaa
     2521 gaagacgcgg cgcggtacta ttcctgcgcg cgcaaaggat cgcgtgcatc aaaaggaagt
     2581 gatcgcaaat agcaaggacc ccagcggggc gtttgttgta atttaatccg tagcagagtc
     2641 tgcctgcccc caaggagaag cccatgaccg cgccgcaccc ctccaagacc catataggca
     2701 accacaaact gcatcccgaa acgctgatgc tgaattacgg atatgaccca gagctttcgg
     2761 agggggctgt caagccgccg atctttctga cctcgacctt cgtcttccac tccgccgagg
     2821 aaggccgcga cttcttcgat ttcgtgtccg gccggcgcga gccgcccgaa ggcgtcggtg
     2881 ccggcctcgt ttactcccgc ttcaatcatc cgaacagcga gatcgtcgaa gaccggctcg
     2941 ccatctacga acgggccgaa gccggcgccc tcttttcctc cggcatgtcg gcgatcgcca
     3001 ccacgcttct cgctttcgtg aggccgggcg attcaatcct gcattcgcag ccgctttacg
     3061 gcggcacgga aaccctgctg gccaagacgt tcctcaatct cggtatttcc gccaccggtt
     3121 ttgccgatgg tgtcgatgag gcggccgtca gcgccgcggc ggaagaagcg atgagcaagg
     3181 gacgggtctc catgatcctg atagagaccc cggccaatcc cacgaacagc cttgtcgatg
     3241 tcgcgatgat ccggcgcatc gccgaaagga tcgaggaaag acaggcgcat cggccgatcg
     3301 ttgcctgcga caacaccctg ctcggtcccg tctttcaaca ccctatcgaa cacggcgccg
     3361 atctttccct ttattcgttg accaagtatg tcggcggcca ttccgatctc atcgccggcg
     3421 ccgtcctcgg ttccaaagca ctgatcagac aggttaaggc acttcgcggc tcgatcggca
     3481 cgcaactcga cccgcattcc tgctggatga tcggccgctc tctagaaacc ctgtccgtgc
     3541 gaatggaaaa ggcgaacgaa aacgcccgca tcgtcgccga attcctgcgc gaccatccca
     3601 aggtcgagca catccactat ctgccgttcc acgacccgga ggcgccggtc ggccgagtct
     3661 tcgccgcgca atgcacgggc gcgggatcaa ccttctcctt cgacatcgcc ggcggccagg
     3721 aggctgcctt ccgcttcctc aacgcactgc agatattcaa gctggccgtc agtctcggag
     3781 gcacggaatc gctcgcgagc cacccggcgg cgatgacgca ttcgggcgtg cctatcgagg
     3841 tccgcgcccg catcggtgtg ctcgaatcca cgatccgcct gtcgatcggc attgagcacc
     3901 cggacgatct cgtcgccgac gtcgccaacg cgctgacgac gatctagagc ctgagtcgag
     3961 acccggaccg tccagaccgt tccggaattg attctctcgt cttccatgcc gcttcctgct
     4021 gcgttttcga gtaaaacggg catgaagcgg cgcaggacta cactgtctca cgctgcctgc
     4081 agcgccttct gaacggcctt cggagcgcgg tcgatcacca gaagataagc gcgagtcggc
     4141 ccttccggct ggcgcgaacc ctgttcccaa tggcgcaatg tgttgacgct gaacccgaat
     4201 cgtccggcaa attcttcctg tgtcatttcg agtttcgtgc ggatcgcctt cacgtccatc
     4261 cgctcgggca catggacgcg aaaggcgttc gcatcggcac tgccctccgc acaggcgagc
     4321 gcttcgttca ggccgcgccg gatgctgtcg gcaaccttgc tcatcgcttt ctcctcttga
     4381 atgcatccac cagcatggtc gtcaactggc ggaagtcgtt cctgtcctgc tggcccagat
     4441 cggcccgcat gttcttggcg caggcggtga gtgcaaagag cggcatgtcg gcgtcatggt
     4501 aaaaatagac cacccgcgcg gcgccacgtt tgcctcgtcc ttcaagctct cagcgaacct
     4561 tgcggatgcc gcccgttccc tgacgagatc gcctgccgtg ggattgtggg caagatagtc
     4621 caccaacaag gcgcgctcgt catcgttcat gagtttgcgg gtcgcagaca ggaactccgg
     4681 cgtctccacg acactgacgg gaaccctttt caccatggtc ggaatactac tgagtcagta
     4741 ggtgcaatcc aggaaataat ccactggatt acccgctcac gcccctcatg gctgcgcttc
     4801 cgtgttccgc ctcgatcaac tctccgcgtg cgaaagcacg ttgacgatgt tgccgaaggg
     4861 atcgcgcaga aagaaccggc gtacgcccca gtcttcgtcg gtgatatcgt agacgatctc
     4921 tgtgcccgcg gcctttgcgc gacgatacgc ttcatccaca tcatccactt cgatcgagag
     4981 cgccggcacc ggcgttcccg atccgccctc ggtggcgaag ctcacctggg gcatggcgga
     5041 actgccatcc gccgcatagg tgacgatcca gccgtgattc atcacgatct ccaggccgag
     5101 cagggccctg tagaagcgat ctgcctcgag cagatcggat acctgaaaat taggcatgat
     5161 gcgtcggact ttcatttgcc cctcccggct ggttgctgca cactcggttc cgaaagcgcc
     5221 agctttacga gcgtagccgc ggcctcgccc gccgtctcca tatagctcgg atcacggtgg
     5281 agcaaaacga ccgcgaagct gccgtcgagg agcagcagca tctgccgcgc gagcctggcc
     5341 gcctctgcaa ttccttccgt ctcgaagctc tgacgcagcc agtcctcgaa cttccttttg
     5401 tgcgctgccg ctatgcggat cgccgggtgg ccgggcatat tggcgagttc cgccgaagtg
     5461 cggaggaaac cgcagccctt ccatttcggg tgccgggcag cccgggcgag attgagaaaa
     5521 atggctttga tctttgacgc cgcatcaccg tcggtttcgc tgaaccactt ctggaagagc
     5581 ttgaggttgg gctggtcacg ctcctcaaga taggcggcaa tcaactcgtc cttgctcttg
     5641 aaatgatagt agagagtgcg cttcgtcaag ccggccgcct cggcaacggc gtccacgctg
     5701 acggcgcgaa ttccttccgc atagaacagc ctggcagcgg cggaaacgat acgttcgcgt
     5761 gtgttttgtg tcgccgccat aatccaggta taccgactag tgaatataca ttcctttgtc
     5821 tcccacttag cctccgttcg tcaacacccg acgggagaca aacatgtccg atactgtgct
     5881 tctgaaaatt tcgggcggaa ccgccctcct gacgctcaac cggcccgaaa ggctgaatgc
     5941 gctcaattac gagctgatcg accggctttt gaccctcctc gatcgcctcg aggtggacgc
     6001 caaggtgcat gccgtcatcc tcaccggagc gggtgatcga gccttttcgg caggcggcga
     6061 cattcacgaa ttctcccaca gcgtggccga aggcgtgaac gccgcgatcc gcgatttcgt
     6121 gcgaagaggg cagcagctta ccagccgtct cgaggccttt ccgaagcctg tgatcgccgc
     6181 cgtcaacggc atcgcctatg gcggcggctg cgaaatcacg gaggcggtgc atctcgcgat
     6241 cgcgagcgac cggtcgcgat ttgccaagcc ggagatcaag cttggcatgc cgcccacttt
     6301 cggcggcacg cagagactgc cgcgccttgc cggacgcaag cgcgcgctgg agctacttct
     6361 caccggcgac gcgttttcgg ctgagcgcgc gctggagatg gggctggtaa atgcggtggt
     6421 tccgcacgcg gatcttatcg agaccgcccg agcgctcgcg gcgcgcatta tcagccactc
     6481 tcctgttgcg accgccgcta tcatctcggc cgtgacgcgc ggcctcaaca tggcgatcgg
     6541 cgaaggtctg ctttgcgaga gcgagcaatt cgcacgaatg gttccgaccc acgacctcaa
     6601 cgaaggcctc gccgcctgga aagagcggcg cgagccgcgc tatgccggcc gctgagattg
     6661 cccgatcatc aggtccgggc gaagccgagg acgaagagcg ccagagcagc ggtcgaagcg
     6721 aagctgcgca cgtggttcca gcggacccat tcggtcagat agcgctgctg ccagagttcg
     6781 gtggctcctt gtccggcagg ggcggcggca agcgcttcgt tcagcggcac gttgacggct
     6841 atcgtcaccg cgagcgtgcc gatgagatag acgagtccgc cagcagccag gaaatagctc
     6901 ccctgccctc cccagatgac ggccatgacc aggagcacca ggccaagcag cgccgttccc
     6961 atgaaggcga tgagaaacag cgggttctgg atcaccacgt taatggcgtt catcacggcg
     7021 acgccttgct cgggcgggag tcgcgaaagc gcctgcataa tgcagaccga aaagacgaag
     7081 aacagcccgg ccatcaggcc ggatccgatc acggcggcaa atgcgagcac aggaacaagg
     7141 gtaaccatcg caacactcca ggagggaatt gagccgcttc gggtcgcttc tctcgtttca
     7201 gacttgaagc agcgtcgacg aaagccagcc tcccgcaaat ccagccctgc tcaacccctg
     7261 acgaaaggcc ggaatgccgc gcgtcagttc ccaaaccagg ccgctcctcc aattctcgat
     7321 catcatgacg acgagccctt ggtcaaggcc gacgagtcta tcgtccatcc atccctcggg
     7381 accgtccccc ggcaggctgg gattgaaacc gccgggaagg cgttcctcct tcaccagggc
     7441 ggggtaacgc gacatcagat gaaaaagact gccgagacac gcgtccggtt cgaatggcag
     7501 cccggccagc ggcgcccagg gaacgagtgt tccgtcgtcg gcaccaaacg gtgcgccgcg
     7561 tgcctcgtag cccagcaact tctgccgccg gccgtcgcga agccgaaacc agcctttcgg
     7621 cgcatgacag gcgctgaaac cccagaggtc gcggcaatag ccggcgaatc catgagggtt
     7681 ttcctcggca tgggcgcgct gcagccggat ggcgcggcgg gtgttatcga aatagtcggt
     7741 ggccctgtcg cgcatcccct tatcccggat gctgcgaaaa tcgatccatg cctgcggaaa
     7801 aaggtggacg aagagcgcgg cggcatggag atgcgccgcc ccatcgagtt ccagccactc
     7861 atgcgctgcc gtgtaggcct cgtagttcgg cggcatgatc gggcgcgtgg gcgagccgag
     7921 tgccaggacg tagaggagca gcgcctcgct atgaccccgc cagcggtgtt tcaaaaatcg
     7981 ccccggcggg cgccacccca tcgtgaccgt gtcgccgcca ttcagcgccc agtaccaatc
     8041 cgccctctcg tagaggagcg ccgcaagccg cctgagctca ctctcctctt cgctgcggcc
     8101 agagaaataa gctgccgccg tcaaggcacc ggcgaggagc aggctggtgt cgatcgtgga
     8161 gagctcactg cgccagacgc gatcccccgt ccgcatgtcg aggaaatggt agtagaatcc
     8221 gcgataaccg gtcgcgctcg catcgctccc ctgacggctt gccgcgaaaa accggagggt
     8281 ggtcagcacg cgccaggcag cgtccgaccg ggcgatccag ccgcgttcga ccgcgaccgg
     8341 ataggccgca agtccgaaac ccgtggcggc gatgctcgac ggagaacccg cgcgagacgt
     8401 gtcggcgacg aggccgcttc gcatgtccga ataccgaaga aagtattcga aggcggcgcg
     8461 ctgcagcccg tcgatgcagg cgatatccga tgtgcggctg tggagagaca tgccagccta
     8521 ctggtcgacg aggttggtca cattgcggca ggccacgcag accaaccgcg atcaccgaat
     8581 attgtaggtc tgcatcgctc cgacagtcgc cgatctcaaa acctgtgata cattcatgga
     8641 atgacatcga cccggacggc gacatcgctc taaggcgcct cgcggtaccc gggtgcaggg
     8701 gcagaacgcc cgacgcgtga tccacggtga ttggctgatg cgatgttagg cacgatggca
     8761 ttgatcctgg cactgagcgg agctccgata cagtcggcag ccatttccgc tgacgtcgac
     8821 gtagaactcc tgctggccgt cgacatgtcc ggctcgatgg acatggagga ggcgcgcgtg
     8881 cagcgctccg gatatctgca ggcgctgcgg catccggatt tcatcaatgc ggtccaggga
     8941 ggcctcctcg ggcggatcgc cataggctat ttcgaatggg cagggctcgt aaacgaggcc
     9001 tcagtcgtga gctggcaagt gatcgaaagt tctgccgacg ccgaagcctt cgccggcaag
     9061 ctggaggctc ggccaatcgg aacacggcgc ggcacctcga tctcgaacgc gatcctgttt
     9121 ggttcggacc tcatcgattc gaacgcatat tcgggtacgc gaagggtcat cgacatctcc
     9181 ggcgacgggc cgaacaatac cgggccgccg gttacacccg cacgcaacga cgccctatcg
     9241 cggggcatta taatcaacgg tcttgcaatc ctcatccgcc cttcggtctc gaccgggccg
     9301 ctcgaccggt attacgccga atgcgtcatt ggcggccccg gctccttcgt gttgcccgtg
     9361 catgaacccg aggatttcgc ggtcgcaatc cgtcagaagc tgatcctcga ggtaagcggg
     9421 cgcgagcccg atccggcgct ccgcctggcg gccggcgaaa atgcggcgga ctgcatgata
     9481 ggcgagaagc tccggccggg atttctcgac agggtctatc cggaactgga tcgctgacgc
     9541 ttgctcttca tatccccacc ttcctgtatg ccacaggaat ggtgaggacg aaagaagtgc
     9601 ggtcgggtgc ggtagcagcg caggcgggtt tccccgcagc gcgctattgc agcagggtcg
     9661 ttctattgtc gaagcccgca gcggcaatga cgagctcgcc gcgatcccgc aattcgttgg
     9721 cgaccgcttg cagtgccata tcgatgcaat actcgacggc ctgtgcctcc aaggcacgag
     9781 cgctctcgcg aatgtggctc aacattcggg caatgctcgc aagttccacc tcggtatccg
     9841 tcaaggacga agaatgatta gtcatatgaa cccccaatcc atgcctgtga tgagggcgac
     9901 tataaacgag ttcggcattt ccgcgcgttt cacgagcgtt gcacacgctc aggtggagta
     9961 tttagcggat cttcgcccgg agccccattg cccgctcccg tcacgatgcg agcgctttgg
    10021 atagtgcacg cggaccaaaa cggcgcgctc gatcaccatc cggattctcg agtttgggaa
    10081 cgaagatctt gacgaccgag aacggaagcg cgttcgccga cagacgaagc gcaattgcag
    10141 attgcacgcc ggcgctcgtc aggtgatcaa cggtgtggcg cagcagcgct tcaaggcttc
    10201 cgccgacctg cgggctggcg atggcccgtc tggatggctc ggcgaggaag gcctgccgcg
    10261 tcagttccgg caagggccgg ttgaaggtct cgggaaagac atcgtcccgg gcaccactga
    10321 tgaaggtgag ccgggactgc gccgcttctg tcaccgccct gatcgccgcc cgggcgggaa
    10381 aaacatgtgc gccgcagccg ctcgtcactt cgacgaagcg gccaccgccc ctggtcgcga
    10441 tatcgggtgg gccgagcagc gccaggaaac agggaatgcc tatgtcgctg gtgatttcga
    10501 aaagccggag atcgagtccg gcggccccaa tgcgctcaac gagaccgttc aacgctgcat
    10561 cgcccaggct ctcgggagcg acacagcacc cgtaacggtg ctcccgcccc gagatgcccc
    10621 agaggacgtg cgcgtctcgc tcgatgcgct ccagcagtcc gtgcaatatc gcttcttcca
    10681 cgacgtttcc cgacgcaagt ccatccgacg acatccagaa acgcgaatgc agggtacggt
    10741 cgagcagcgc cgctgcgagc ggcacgagta tctcgcggcc ggagatcagg tcggagccga
    10801 gggcccatgc gagttcttcg tccggcccta tatcctgctg cccggccgca atcaggcagg
    10861 gaagcagctc cacggtccgt ccggatgcac gcaaggtccg ggccgtggcg accattgttc
    10921 cgacggcggg ctcgcaggca acggcgcgct ccagcgcctc catgaccgcg gaaaccttcg
    10981 cctccggatc cgtcaatccc ttgccctgcg caaccgcgat cgatcgtgcg ttcggcgtgt
    11041 aggcgcacca gaccgggagc ccgatcctgt cgaggcccgt gtgccgtgcg atgcgggtca
    11101 cgccgaaccg ggaaagcagt ggccggacac ggtcgaacgt ctcttccggg ctcagaacgc
    11161 gatcggaata agcattgcgc gtgtctgcag gactgccgac agcgaagccg atcacccgtc
    11221 gaaatgcccc gaaaacacct tgtcggccga cgacaccgct actgcgagat caacattctt
    11281 gacgatcgtc ccgccctgca ggcggagctt gttcgccgtg gcgagatcgc ccgacacctg
    11341 atcgagcggc ctgaccgttc catttttcag atccgccagc cacaaacctt gctcgccggc
    11401 aataccaatt actacgactt ctgccatatc gcttcccctc atcatcaaaa ccccgctctt
    11461 ttcagcccct cgcgatagag gtccttctgc cattgttcct tcatcggaac gacggcgagc
    11521 cacttgtcga catcgaatgt cggattggcc ctcagggcct tcaccttgta tgaccgcgct
    11581 ttcttctgat cgccgagcat cgcccagctt gctgcaagca gccggtcgcc cggcgacttg
    11641 tccttcattt tctgaacgta gccgatcgca tcctcatact cttcgagaaa gtagctggct
    11701 ccggcagcgc tccagaaata catgtccggc gccaggggat taagcgaaag cgccttgccg
    11761 agcttgtcga gagcctcacg cgggcgggag gcatggacga gcgtgtccgc atggctgtac
    11821 agcacgtcgg cataatgcgg gctcagattt tcggcgcggt ccagcgccgc aagacttcca
    11881 tcgaggtcgc cctgataaag tctgacgacg ccgaattcgc gatgtgctcc gggaagctct
    11941 tcatcgctct cgatcgcttc cttggcgtga cgctcggcta ccgtcaaaag ctcctggtcg
    12001 ccccgagccg tcaggaccca ctcgatcgca taggtgcgtg cgatgccgct tagcgccggg
    12061 gcaaaatccg gcttgtgcct gagcgccgtc ttgaaatcgc ggcgtgccct gcggatttcg
    12121 ggaaggccga cgttcgaaag gtttcgcagg ccggcgagat aggcgtaata ggcgtccgga
    12181 ttggtcacgt aatcgaggtg cccgatacgc ccggtctcca cctgttccgc taccgcgctg
    12241 gccacgtgaa aggcaatttc ctgacgctgt tgcaggagcc cgaccggaga gatcgaaaag
    12301 cgctccgccc agacgatcgc gtcggacggc aggaagatga gttgagtaaa cagcccctgg
    12361 tccgacatgc gacagtcgag cgcataagtg acggcatgtt tttccaggaa ggcagccttg
    12421 tccgccgcat cccgaatacg ctcggcagtg taaggggcaa caaccgacat cgagcgcagc
    12481 gcgcataatc cgatcgtgat gtcttcgacc acggccatgc tgaccgcgtg aagcatcgga
    12541 tcactgccga aagccgcggg cggaagcagc gcaacgcgcg gtgcgggcgc aaccggcggg
    12601 gttatcgcat cccttgccgg cgcccggggc gactcccctg caaaggcccc ctgccgcagc
    12661 caggccccgt ccggcgagcc tttcccgatg acgagaccca cgccggtcaa ccgctccagg
    12721 attgcgcgca cggcagtatc cgccggatcg agttcgagga gatgcatgca cgccgtccgc
    12781 agcatcgacc tgtcggcaaa tcgctctccg ccggctaaaa gtgccgcgcg cagcttttgc
    12841 gtaaacacgc tccgctgctc tccaacccag tccgcataac gcccgggagg cacatcggcg
    12901 cctgctagga acgtatcgcg ccagagcgag agcccggcgc gaaacgcttc ctccgagctc
    12961 ccgagcgcct cgaaaccggc ggcgtcgcag gcaatctccc ccagcgtcac atctatttcc
    13021 gtcgccgacg tgagcggccc cgagttcgcg gcaaggtggc gcatgcgcca cagggtagag
    13081 cgcaggttct tgaaagcgac gctcttctcc cgctcgggcc agatcagcat cgagagcttt
    13141 tcgcgggaga ccgttctctg cccggatatg ctgaggtagg ccagaataag caggccccgc
    13201 tccgggcacg ccacgaccac gccgccggaa tcgaccagcc gcaattcccc gaatgtctgc
    13261 agatgaaaat gcggcaccgc cacgaaaacc ccaaacggct ttagatcaat atgattttag
    13321 gtcaccaccg gccgccgccg gcgaatgcat cgaaatctcg ttcacccagc cctcttccac
    13381 cccttagggc aatcacacct cggtccgcag agcggatagc cagtgtgcgc ggttttcagc
    13441 ccagatgcag ccatgcatga acatgcttga aaaggcggaa catggcaacc gatgccgctt
    13501 atagctccca aggggaacct gaaagcgccg acggagctcc ccattattgt tccacgcccg
    13561 cctcaacgct attttcaacg cgttcgaagc cgataccgtg agcaagcgct gtcagaacac
    13621 caattaaagt ggactcatcc ggtacaacca tgacgcaacg tgaatggcgc atttcggaac
    13681 tcgtcaatca actcctcacc ctcggggtga agcccggagg cgttcttgtc gttcactctt
    13741 cgtttcgcag cgtccggccg gtcgaaggcg gtccggccgg catgatcgcc gctctgcgca
    13801 ccgccatcgg cccggaaggc acgctcgtca tgccctcctg gtcgggcctt gacgacgagc
    13861 cattcgagcc ggcgacgacc tcagcaacat cggatctggg aatactcgcc gatactttct
    13921 ggcgtcttga gggtgtggtg cgcagcgacc atccgttcgc ctttgcagcg gcgggaccgc
    13981 ttgccgcacg catcacatcg gaccccctgc ccctgccccc gcattgtccc cccagtccga
    14041 tagggcgtat ccatgaactc gacggacagg tgatactcct cggcgtcgga cacgattcga
    14101 acaccacctt gcatctcgcc gagctgatgt ccaaggttcc ttatggagtg ccgagacact
    14161 gcacgatcgt cgaaaatggc agccgggtcc gcattgccta tctggagaat gatcactgtt
    14221 gccagaactt cagcctggcc gacgtctggt tgaggcgaaa cggcctccag aaggaggggc
    14281 agatcggcaa cgcccatgcc cgcctggtcc gctcacgcga catcgtgaaa atcgcaatgg
    14341 aacaattggc ccacgacccg ctcgtcttcc tgcatccggc agaagtggcg tgcgaagaat
    14401 gcgatgcagc acgccagtcg atcggctatg ggcgttcgtg agagcctttc ggcgccggat
    14461 cacgctcgct ctcagttttc tttatcgtcc ccggcacgaa acccacccca aagccgaata
    14521 gacggccatt ttttccaatg tctccaatgt cgggttcgct gtgccggctt cgatttcggc
    14581 aacctgcctc ctggtgagcg ccagcatctt cgcaaactcc tcttgcgtca tgccgaagcc
    14641 cttgcgaatt tcagcaacgg catggggcaa gcgcagctca ccgctgcgcg cacggttcgc
    14701 cagatcgcgt cgattttcca ggacttcttc tttggtcggc ttcttccagc ggggcatcag
    14761 cggtctccgt tccggctcag gatagcgaca ccagaacgct ctcggcgatt tccgcgcagc
    14821 gccccatgcc gcgatcaacg caggaatggc gcagcagcac tatacgaagc cgtgcggacc
    14881 cgagcgcatc atcgattcag gtttcgagcg ctgcaagaca tatgtggccc gggaggtttc
    14941 gctttcgcct aagcagaatt ccggcgagac agacccggga aaatgaagga aaaacgacgt
    15001 tcaatgaggg aatggtgggc ccggagggac tcgaaccccc aaccaagcgg ttatgagccg
    15061 ccggctctaa ccattgagct acaggccctg ccgtcctcgt ggtcggcggt tgcggaccaa
    15121 tggcagtccg cagtgctggc tctagcctaa atctttttgg ccgacaagcc attgccgcaa
    15181 tagctacaca atcggtaagc atggaatcag cgacaaacaa ccggagagaa accccgatga
    15241 gctctacacg cattgcccgc accgtacatg tcgcagcagt tgcagccgca tttgctgggg
    15301 ccttcgcggc ggcagcagcc gctcaagaca gtgccgccgg caaggatggc aagggagacg
    15361 gaaaggggcg tccggatgcc gtccggggcc gccaggcggt catcaaggtt tccggggaag
    15421 gccgttcgac gactgcgccg gacatggcgg ttctgcagct cagcgtagtc aaagacgcaa
    15481 aaacggcgcg cgaggcgctc gatgccaaca acaaggcgat ggcggacgtg ctctcggcat
    15541 tgaagcaggc cgggatcgcc gagcgcgacc ttcagacgag cggcttttcg atcaatccgc
    15601 aatatcacta tcctcagaac aatgacggcg gtaatcggcc accggaactg gtgggctacc
    15661 aggtcgtcaa cggcgtcggt gttcgcgtgc gggatctggg gcagctcggc gagatcctcg
    15721 acaaatccgt aagcctcggc gtcaatcagg gcggcggcat cgagttcacc aacgacaagc
    15781 cggaagccgt gatcacggag gcccgcaagg ccgcggtcgc cgatgcaatc aacaaggcaa
    15841 gggttctggc agaggcggcc ggcgtctcgc tcggccgtct gattgaaatt tcggaacagc
    15901 cctcccggcc cgagccgatt cccgtcgtgc gaagcatggc caaggaattt gccgccgatt
    15961 cggttcccat cgcaacgggc gagaatgcct acaacgtcaa cgtcaacgtg acattcgcca
    16021 tcgaccagta gcgctgtgct tgatcacgat attccaggtc ggatcgatct aaaacatcgt
    16081 gattgatttc aaagcgttga gacgcggggt gccggcggaa agccgcatgc attcttcctt
    16141 gcgcaaaact aaggagcccc cacgccgagg cgtgagggct ccttttccgt cagccggggg
    16201 agacaagacg gaaattcggg cttttaccag cggccgatga ccgggcatcc gcgggcattg
    16261 gcgaacacga tggcctggcg gtggccgcgg cggcggcctt cgacgacgac gcggcggccc
    16321 gttacgtccg cgacataggc gcggcgaagg ccacggtcgc gtgccttctc gacggcgaga
    16381 ccgggtgcac agcgaccacg gcggtcacgg cggtcgtagt gcccgcggcc ccgccagtcg
    16441 tcgtgacggt cgtaatcgcg atactggacg ccacccgggc cgatttcgag ggtgagcgac
    16501 tgggcagagg cagtggaaac cagaccggtc aatccgatca cggcggcaat ggcggcatta
    16561 acgaggaact tcttcatggt ttttctccgg tgggacgaag cggttctgct tgactgttga
    16621 ggcaaaaata gcccggccaa actgaacggc accggaactg tccgttcatg cggtattcag
    16681 gttgatcccg ccctgccacg cactacgaat cgtgttcagc ccgcgagttc ccgctcgaag
    16741 agccggatgt tacgatattg gctgagccgc gtgatcaggc cgtcctcgat ctcgaagaca
    16801 aagacgctcg cgatggaata ggcctgaccg gaggcgtcgg gaaagccggc caaagtctcg
    16861 cggtaagtgc cgcgcgcggt cgtgtccgca gccacgcgct ggccggcggc gtctcgcatc
    16921 agcacgatgt cactcaagct ctcgtcgaaa tggcgcagat agttcatcat ccagctcctg
    16981 agcgagccgg caccgagggt tcgctctccg ctgagcgagt cgaacgcaac gtcctcgtcg
    17041 acgaggcggg aaagcgcgtc gaagtcgcga tcgttcaggg cttccatgaa acggctggct
    17101 atcgtctggg cgtctgtcat tttctcctcc gaaaccggcc ccgcttccac tctacgcaga
    17161 atgcctgccg cgccgaaaga gaaaacggca gcggcgaacg gttgcctcga tcctcaactg
    17221 ccgatgtgca gaacgatctc gcgacggtgc ggccggtcac ggtgctcaaa gagataaagc
    17281 ccctgccagg ttccaagcgc caggcgcccc ttcatgatgg ggacgccgag cgacacctgt
    17341 gtcagtgccg acttgatatg ggcgggcatg tcgtccggcc cctccatcct gtgcacgatc
    17401 cagtccatcg agggatcgga agacggcggt accaaccggt ggaagaatgc acccaggtca
    17461 cgtttcacgt ccgggtcggc attctcctgg atgatcagcg aagccgaggt atggcgcaca
    17521 aaaaccgtga gcagtccctc ggccacgccg gtggcgcgca cgaattcgcc ggcctcggct
    17581 gtgaactcgt aaagcccctg ccccgtcgtc gacatggtga tgacggtctg cgccattctc
    17641 accccacttt accctttgaa caggaaaggc tctaaagttc gagaaaggcc tcgaacccgc
    17701 catagatcag gcgcttgcca tcgaaaacat ccttccacgc gtcaccctgg agcctgggat
    17761 ccgccatgac cttggcgacg atcgcgtcgc ggtcctgccg cgaccggtag acgatccatg
    17821 aaaagacgac cgtctcgtcg tccgtcgcct gaaccgcacg cgggaaggaa gtgagttcgc
    17881 cgcggggaac gtcgtcgccg atgcattcga cgtaattgag cgcgccatgc tccttccaga
    17941 ccgcacccgc ctcgctggcc atcttcttgt atgcctccag attggccgtc ggcactgcta
    18001 cgataaaacc atccacatag gccattttcg tctcctccat tctttgaaag acaatacaag
    18061 gacgatccag gggtacagat tccgacgggg aggcgacatt ttaatggctg gcttaacggc
    18121 ttgcgtcatc cgcccgggtc acgaattgca gccgcgcaat tggcgcgcgt agacagcggc
    18181 catgccggac gcccgtttgg cgcccgcctt cgccgtggcg ctccagttgc cgcgggcata
    18241 accgctgtgg ccgtggtaat aggcgatata gagtctgtac gtgtcgttca gggcaatgcc
    18301 gttccgcttg tggctctgat tgtggtacca ggcgataaag cggatcgcgt ccccgaaatc
    18361 cgaccggcgt gccgtccatc ggcccgtttc tgcctgatat cgcgcccagg tgccgtcaag
    18421 cgcctgcgaa tatccatagg ccgaggaaat ccttgtccac ggaatgaagc cgaggagttt
    18481 cgtccgcggc ggcttggcat tatggcggaa gccggactcc gtatagaccg tcgccatcag
    18541 caccggaacg ggcacgccat attcacgctc tgccgcatag gcagcccggc gccaattgtt
    18601 gaaaagattg tctcgctgct cgaaaaccgc acaggcgttc cgggtctctc tcggcaccgt
    18661 tccgcagccg gccaacaaca ggaggacgac gacaaaaacg caacgcatcg cggaacctct
    18721 cgtttgcgag agattgataa aatgtaaatg ttaaggatcg gtttttatgc gatggccgat
    18781 taccaggctg tgggacatgc cgcgaacgcc caaacccctg aggaactgaa ggggttcctt
    18841 cgccccgctt gcggggagaa ggtggccgcc aggccggata aggccgaagg gctttccgaa
    18901 cggaagccgt acactctttt ccttgtcccg ctctatccca gcgtaccgat aagttcgcgg
    18961 taagccgcct cggggaaggc cttcagagta cgggttcgga cgtttccgtt catgccgagc
    19021 gtcaaggcaa aacgcgcagc gaccgcatcg tccggcgctt cgcagatcgc caccaggtca
    19081 tgttcgccca tcgtcaggta gacgtccttg aaggacccgc ccatatcctc gagcaccttc
    19141 ttggccgcat cgagccgctt cggcgactcg cgtacgttcc ggatcccctg ctcggtccaa
    19201 ttgagaagca cgacgtaagt ggtcatctca cacctcccgc aaagcatccc gccttcggtc
    19261 gaaggcgtcc aagatgctct tatctgaaaa ggttggcgcg cattcgcgcg ttcatgcgcg
    19321 gcctcgggac gccatactcc cggcgatggg aacgagcgac cttcactgcc gcaaggcgca
    19381 aagtataaag catttcgagg aaatcggcgt acggtttcgc gccgggaaat cgagtagagc
    19441 ggaaatgaaa aagccgggcg ctaggcccgg cttcgtcatc atgaaacttc ctgggatcag
    19501 ctgtccagga acgagcgcag cttgcgcgag cggctcggat gcttgagctt gcgcagcgcc
    19561 ttggcttcga tctgccggat gcgttcgcgg gtgaccgaga actgctggcc gacttcttcc
    19621 agcgtgtggt cggtgttcat gccgatgccg aaacgcatgc gcagcacacg ctcctctctc
    19681 ggcgtgagcg aggcgagcac gcgagtcgtc gtctctctga ggttcgcctg aatggccgcg
    19741 tcgatcggca gcagcgcatt cttgtcctcg atgaaatcgc cgagatgcga atcttcctcg
    19801 tcgccaacgg gggtttcgag cgagatcggc tctttggcga tcttcagaac cttgcgcacc
    19861 ttctcgagcg gcattgcgag cttttccgcc agttcctccg gcgtcggctc gcggccgatc
    19921 tcgtgaagca tctggcgcga ggtacggacg atcttgttga tcgtctcgat catgtgcacc
    19981 gggatgcgga tcgtgcgggc ctggtcggcg atcgaacggg tgatcgcctg tcggatccac
    20041 caggtcgcat aggtcgagaa cttgtagccg cggcggtatt cgaatttgtc aaccgccttc
    20101 atgaggccga tattgccttc ctggatgaga tcgaggaact gaagcccgcg gttcgtgtac
    20161 ttcttggcga tcgaaatcac gagacggagg tttgcctcga ccatttcctt cttggcaatg
    20221 cgtgcttcgc gctcgccctt ctgcaccatg gacacgatgc ggcggaattc ggcgatggaa
    20281 atgccggtct ccgtcgcgag attctggatc tcctggcgga tgtcgcggat cgtctggttc
    20341 tccgccctgg caaactcctt ccagcctttg cccgcgagat tgctgatcga cttcatccag
    20401 ttcggatcga gctcggcgcc ggaatactgc tccaggaaag cctcgcgctt gacaccatag
    20461 gattcggcca ggcgcagcag cctgccctcg ttctgcgtca ggcgcttgga gatgtcgtaa
    20521 agctgctcga ccagagcgtc gatgcggttc tggttgagcg acagcgactt caccgccttg
    20581 atcagctcgt ccttcagttc cttatagcgg cgctcctgtg ccggcgacag agttccggtc
    20641 gcggcaaggc gcgcctcgac ctgctggtcc tgcagcttgc ggagcttctt gtaagtctcg
    20701 gcgatgacgt ccagcgtctc catcacctgc gggcgcagtt ccgcttccat cgcggcgagc
    20761 gagaggttcg actcgtcgtc gtcgtcctcc tcttcctcgg cgggctggcc ttcgccgccg
    20821 acattggtga tgtcgtcgtc gttggccgca gcgcgagtct tgcggacctt ttccttctct
    20881 tctgccgcct tgcggtcggc ttcgatcttt tccgggctct gaaactgcgg agcagccttg
    20941 gcttccgggc cggaataggt cgtctcgaga tcgatgatct cgcgcagcag cgtctggcct
    21001 tcgttcaatt cgtcgcgcca gataatcaac gcctggaaag taagcgggct ctcacagagc
    21061 ccggcgatca tcgtttcacg gccagcctcg atgcgcttgg caatggcgat ttcgccttcg
    21121 cgcgacaata gctcgaccga gcccatctcg cgcagataca tgcgcacggg atcgtcggta
    21181 cggtcggtcg gctctttttt cttgctggtc gcaagcgcgg tgccgctggc aggcgcgagt
    21241 tcgccgcctt cgctttcagc atcgtcgctg ctgtcatcgt cgtcactgcc accagcttcc
    21301 tcggcttctt cgtcttcgat gacgttgatg cccatgtcgg aaagcatgga catcgtgtcc
    21361 tcgatctgct cggaagtcac ttcctcggaa ggcagaacgg agtttagctc gtccatcgtc
    21421 acatagccgc gcttcttggc ggccttgatc atcttcttga cagcgtcgtc ggaaagatcg
    21481 agaagcggac cgtccggcgc accttcacgt tcaacgtcgg cttcttcgtt ttctttgact
    21541 tttgttgcca tttaattcgt cgctttcctt gtcgcaaccg gccggcgccc ggtaatcaat
    21601 gccactcgga ggtccgggca cgccgcgtac ccgccaccga ttatttcccc tgacgtaacg
    21661 ggatgatatt taattcctga ttaaccacga cagcgatcgc ggtgaacggg caagcctcga
    21721 cagtcctgcc actgaaacgt ccctggcatg atttcctatc cgccgtacca tgtcgccatt
    21781 tctgctcgaa atggtgattc ccagaatttt tgatcccgtc aagcgtttcc agcgaaaaac
    21841 cgcctaaatc ggcaaaaaac gctattgtac gggatttgcg gctgtacatc agctttcgct
    21901 caacatgtag gagcgcccca cagaaagaca agggccgctc ctccatccga gcacactaca
    21961 tcaaggaaat cggcccagat ggtgcccggg cgcgctgcct accagtccat cacgaccttg
    22021 ccggaattgc cagagcgcat cgcttcgaag ccgtcaccaa actcgtcgat gccgatgcgg
    22081 tgcgtgatta tctgtgaaag gtcaagcccg ccctggacga aggcgatcat cttgtaccag
    22141 gtctcgaaca tctctcgacc atagatgccc ttcagattga gcatcttgaa gatcaccttg
    22201 ttccagtcga tttcgaagcc cgccggcgca atgccgagga ttgcgatctt gccgccattg
    22261 ttcatcttgt cgatcatgtc gcgaaaggcg ggtgcggcac ccgacatttc caggccgaca
    22321 tcgaagccct cggtcatgcc gatcacccgc atcacatcgg cgagattttc cttcgatgcg
    22381 tcgacgacat agtcgatacc gaccttgcgc gcgagatcga ggcggaccgg attgatgtcg
    22441 gtgatcacga ccttgcgggc accgcaccgc ttggcaacca aagcccccat gatgccgatc
    22501 ggcccagcgc cggtgacaag cacgtcttcg ccgacgagat cgaaggagag cgctgtgtgc
    22561 acagcgttgc cgaagggatc gaagatcgcg gcgatctcgt cgggaacgtc gtccgggatc
    22621 gacacgacat tatattccgg cagacacacg aattcggcga aggagccggg acggttgacg
    22681 ccgacgccga gggtgttgcg gcagagatgc cccctgccgg cgcggcaatt gcggcacttg
    22741 ccgcaaacga tgtggccctc tccggaaacc cgctcgccga catgatgctt cgtcacggcc
    22801 ggcccgacct cgacgatttc gcccatgaat tcgtgcccga cgaccatcgg cacgggaatc
    22861 gttttctgcg cccattgatc ccagttccag atatggacat cggtgccgca gatcgccgat
    22921 ttcctgacgc ggatcagaac atcattcggc ccgacttccg ggaccggcac ccgctccatc
    22981 cagagcccca cctcgggcct ggtctttacg agtgccctca tcatattggt cattgctcgc
    23041 tcctccgcgt tgcgcgggac ccccgttcgc cccttaaatc acgttcaact ctcggcccac
    23101 ctcctcgaag acggctatgg cgcggcggat atccgcttcg ctgtgcgcgg cggacatctg
    23161 cgtgcgaatg cgcgcctgtc ctttcggcac gaccgggaag gagaagccga tgacgtatac
    23221 gcccttctca agcatgcgtg cggccatctc ctgcgcgagc gccgcatccc cgagcatgac
    23281 aggaataatc ggatggccct cgccggcgag cgtgaagccg agcctggaca tctctgcccg
    23341 gaaaagcgcc gcgtttgcgg aaagccgttc gcgcagcgca tccccgtttt cgatcagctc
    23401 gaagaccttg agggaagcgg cggcgatgac gggcgcgagc gtgttggaga agagataggg
    23461 ccgcgagcgc tggcgcagcc attcgacgag ctcggccttt gccgacgtat acccgcccga
    23521 agcgccgcca agcgccttgc cgagcgtgcc ggtaatgatg tcgacccggc cctccacccc
    23581 gcaatgctcg gcagagccgc gcccatgcct gccgacgaaa ccgaccgcat ggctgtcgtc
    23641 caccatgacc atcgcaccgt atttctcggc gagatcgcag acgcccgcga gattggcgat
    23701 gatgccgtcc atcgagaaga cgccgtcggt ggcgatcatc ttgaagcggc tgccttccgc
    23761 cttcttcagc tcttcttcca gcgccgccat gtcgttattg gcatagcgga agcgcttggc
    23821 cttggagaga cgcacgccat cgatgatcga agcatggttc agcgcatcgg agatgatcgc
    23881 gtcgtcctcg ccgagcagcg tctcgaacag accgccattg gcatcgaagc aggaggaata
    23941 gagaatcgtg tcctccatgc cgaggaagga ggatatgcgc gcttcgagct ccttgtgctc
    24001 ctcctgcgtg ccgcagatga agcgcaccga cgccatgccg tagccataac ggtcgagggc
    24061 cttcttcgcc gcgtctgcaa gctcctcgtt gccggcaagc ccgagatagt tgttggcaca
    24121 gaaattcagg acacgctgac cggaagcgac ttcgatttcg cccgactgct ttgaggtgat
    24181 gacacgctcg gatttgtaga gaccggcctg cttcaggcct tcaagttccg agctgagatg
    24241 ggagaggaag gccttggtca tggctgagtg ctcgcaatcg atggaaatca ccagctagag
    24301 gactaacacg gtggcacttt tcatggaatc tgtttccgac gccacgtgct gatgcccctc
    24361 accctaaccc tctccccgcg tgcagggagc ggggacgagc acgacgctgg cgctggtctc
    24421 cttcgccccg cttgcgggag aaggtgccgg caggcggatg gagggcggat gatcactcga
    24481 cgtcagccct cgaaagcctc gatcaccgcg aggaaagcct gtccgtacct ctcccgcttg
    24541 gtctctccga taccggggac gcccaggaga tcgtcgaaat cgcgcggtcg gcgcttggca
    24601 agcgcaatca aggtagcgtc cgggaagacg acatagggcg gcacgtccat ctcgcgggcg
    24661 atagtaagac gctcggagcg aagccgctca aacaactcga gatcggagcc cgcgaggtcg
    24721 gaccgctctc gcgtcgcctt ctggccgcgc gccgccttac cggaactcgg gcggtccttg
    24781 cggaagagca cctgccgctc gcggcggaag acgctgcgtg cctcaggctc gagtttcaat
    24841 gccccgaagg cgccgtgatc cacggagatg agccccgcgg cgagcagttg gcggaagatg
    24901 gattgccagg tgcgcgccgg caggtccttg ccggccccga acaccggcat gtcgacatgc
    24961 ccgaagcgct cggtcttttc gttcacgctg cccataagta catcgatcag atggccggtt
    25021 ccgaaacgct cgccggtcct gtaaacggcc gcgagcgcct tgatcgccgc ttccgtaccg
    25081 tcccaggtct cgaccggttt caggcaggtg tcgcaatggc cgcacccgcc cggatgcgct
    25141 tcgccgaaat gcgcgaggac cgcctggcgc cggcagcctg ccgtctcgca aattgcaagc
    25201 agcgaattga gtttcgcccg ctcaattctc ttgacctcct cgggcgcacc gccctcgtcg
    25261 atcattcgcc ggcgctggat gacgtcggcc atgccatagg ccatccacac ttccgaaggc
    25321 agcccgtcgc gcccggccct ccccgtctcc tggtaataag cctccaccga acctggcaga
    25381 tccagatggg caacgtagcg cacatccggt ttgtcgattc ccataccgaa ggcgacggtt
    25441 gcgacgaggc acaaattctc ctccttgagg aaagcgtcct gatgcgcgtc acgcaacgcc
    25501 ctgtccatgc cggcgtgata ggggagcgca cgaatcccct gcgtattcag ccattccgcc
    25561 gtgtcctcga ccttcgcgcg agagaggcaa taaacgatgc cgcttgcatc cttgaagcgc
    25621 gacaggaagc gcagcaattg ctggcgcggc tgatcgcgct ccacgatctc ataggcgatg
    25681 ttcgggcggt cgaaactgga ggtgaaaacc cgcgccgcgc caagtgccag gcgctcgatc
    25741 aggtcggcgc gtgtgtgcgg atccgcggtg gccgtgagcg cgatgcgcgg tacgttcggg
    25801 aagcgttcgg cgaggcagcc gaggccgcga tattccgggc gaaagtcatg tccccattgc
    25861 gaaacgcaat gggcctcgtc gatcgcgaaa agagcaattt cggcaccggc gatcatttcg
    25921 gcgaaaccat cggtgacggc gcgttccggc gtcacataga tgaggtccag agtgccggtc
    25981 gaaagcgaac ggcgaacggc aatcgcctcc tcccgcgtca gggaggaatt gagggcggcc
    26041 gcccggacgc cgagctgctt gagcgcctcc acctgatcgc gcatcaaagc gatcagcggc
    26101 gaaacgacga cgccgacgcc gccacggcag agcgccggaa tctggaagca gagcgatttg
    26161 cccgccccgg tcggaaaaag cacgacggca tcgccgccgg caaccacatg ctcgatgacc
    26221 tcctgctgct gaccgcggaa ggtggaatag ccgtaaatgc gtttcaagag atcgagcgga
    26281 ttgcggacgc cttccgtttc gaacaggcag gcggtgctgt ggctttcggg catggaatcg
    26341 ctttcgtcgg tgcgtacaat atggcgtcgc gggtgctcgc gtgtaaacca caggcagcat
    26401 tccgctagcc tgctgactcg ccgcacgaca gatgattacc gcgccgcagg ccccttcacc
    26461 ctccccgaaa gcacgccgaa gccttcgatg attgcttcga gcttgtccat ccggtgaagc
    26521 tccagctgta cttcctccat ggcgcgcacg agccgctgcc cttgatcggc gtcttcggag
    26581 gccgtggctt ctgcgatttc gcgttcgagt tcccgtttct gccaaagcag cgccttcgtc
    26641 cgccggtgaa gggtcagggc ctggagatag ccttcgcgtg catcctccgg cgccgctgcc
    26701 tcagttgccg tccaaagccg cgcatttcta atctgctggt cgagagcgcc gatcaactgg
    26761 gaaaaaccct ccgcctcaag ctgctccagg agggtttccc gcgtcagccg caacccgttc
    26821 gctgccgcgg cgttcagaac cgcggcccag cagcgctgca ggtcacggtg gtcgaactcg
    26881 atcgtggcga tctcgtcata ttcgtcgaat agcagttgcg gatgattgac gatcgtcaat
    26941 gcgagcacgc tctcgcgcag caccggcggt cgaagcgagc cgccggcctt catcatctgg
    27001 ttgagtttgg aactgccggc agtgccggcc tccacggccg cgcccaggac cgggttcgca
    27061 gctcgcgacc agcccctgcc gccctggcgt ccggcctggc ctccgccctg ccttccgccc
//
