LOCUS       NC_009621              20621 bp    DNA     circular CON 15-MAR-2024
DEFINITION  Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence.
ACCESSION   NC_009621
VERSION     NC_009621.1
KEYWORDS    RefSeq.
SOURCE      Sinorhizobium medicae WSM419 (Ensifer medicae WSM419)
  ORGANISM  Sinorhizobium medicae WSM419
            Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
            Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
REFERENCE   1  (bases 1 to 1245408)
  AUTHORS   Reeve,W., Chain,P., O'Hara,G., Ardley,J., Nandesena,K., Brau,L.,
            Tiwari,R., Malfatti,S., Kiss,H., Lapidus,A., Copeland,A., Nolan,M.,
            Land,M., Hauser,L., Chang,Y.J., Ivanova,N., Mavromatis,K.,
            Markowitz,V., Kyrpides,N., Gollagher,M., Yates,R., Dilworth,M. and
            Howieson,J.
  TITLE     Complete genome sequence of the Medicago microsymbiont Ensifer
            (Sinorhizobium) medicae strain WSM419
  JOURNAL   Stand Genomic Sci 2 (1), 77-86 (2010)
   PUBMED   21304680
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245408)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Dalin,E., Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M.,
            Vergez,L., Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Reeve,W. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED02
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 1245408)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Dalin,E., Tice,H., Pitluck,S., Chain,P., Malfatti,S., Shin,M.,
            Vergez,L., Schmutz,J., Larimer,F., Land,M., Hauser,L., Kyrpides,N.,
            Mikhailova,N., Reeve,W. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (21-JUN-2007) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000017145.1-RS_2024_03_15
            Annotation Date                   :: 03/15/2024 03:53:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,520
            CDSs (total)                      :: 6,452
            Genes (coding)                    :: 6,144
            CDSs (with protein)               :: 6,144
            Genes (RNA)                       :: 68
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 308
            CDSs (without protein)            :: 308
            Pseudo Genes (ambiguous residues) :: 0 of 308
            Pseudo Genes (frameshifted)       :: 194 of 308
            Pseudo Genes (incomplete)         :: 203 of 308
            Pseudo Genes (internal stop)      :: 37 of 308
            Pseudo Genes (multiple problems)  :: 111 of 308
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 331929
            Orig. end                         :: 352550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000740.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4001622
            Source DNA and bacteria available from Wayne Reeve
            (reeve@murdoch.edu.au)
            Contacts: Wayne Reeve (reeve@murdoch.edu.au)
            Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LLNL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20621
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20621
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20621
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10621](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10621
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    120..134
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    219..232
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            267..560
                     /locus_tag="SMED_RS26670"
                     /old_locus_tag="Smed_5365"
     CDS             267..560
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010968341.1"
                     /locus_tag="SMED_RS26670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5365"
                     /product="hypothetical protein"
                     /protein_id="WP_011970245.1"
                     /transl_table=11
                     /translation="MDVFDISSALIWLALGLSGPAFLTAFADQPRGWKSAAETTVGTSV
                     FVAALGLCLSAGAFVATAVAAPVALAVATMFRRNCQRLPMLAVSILCLGIYL"
     gene            complement(591..863)
                     /locus_tag="SMED_RS26675"
                     /old_locus_tag="Smed_5366"
     CDS             complement(591..863)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017272239.1"
                     /locus_tag="SMED_RS26675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5366"
                     /product="hypothetical protein"
                     /protein_id="WP_011970246.1"
                     /transl_table=11
                     /translation="MDMSDRENVSADDAATAPDLLQTAAQCAASDLLDFAAQLAGLAED
                     LKALAAKPIGTLSEPIEPDGQPEASRIETIQPSAPGDEATRHPPD"
     misc_feature    complement(834..845)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.13"
                     /tool="antismash"
     gene            complement(1087..2820)
                     /locus_tag="SMED_RS26680"
                     /old_locus_tag="Smed_5367"
     CDS             complement(1087..2820)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970247.1"
                     /locus_tag="SMED_RS26680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5367"
                     /product="penicillin-binding protein 2"
                     /protein_id="WP_011970247.1"
                     /transl_table=11
                     /translation="MRKHAFTLRSRAHSRRVRIICIMAAFAAIFTGIFLRLVQFGMEQE
                     ASHGISITYDRAPGGRPAIVDRNGELLATDIPIASLFIEPRSIPDLDEAVEKLTGIFPE
                     LDARELHSRLRSKDAFTWIKRQITPDKQQAVIDSGLAAIGFRPENRRLYPNGSLAAHIL
                     GAVDIDNRGIAGIEKWIDANWLADLRGAGLELKGRELQRIELSIDLRVQYALEQELGKA
                     ITKFGAAAGAGLLLDVTNGEVLALASYPDFDPNNPENAFKPDRINRVTAGVFEMGSTFK
                     ALTTAMALESGRFNLESVVDASKPLNFGRMRIHDYRGKYRPLTIPEAFVHSSNIVMAKM
                     ALALGPEASRTFLGRFGALSPLATELPESAAPLLPSSWSEVATATVSFGHGIAVTPLQA
                     STAVAALANGGRLIRPTFIKDSPVSERTIAEDLVSSDTSEAIRHLLRLNTAVGSATRAN
                     VPGYAIGGKTGTAEKVVGGRYSRELNVTSFMGIVPADNPRYLLLTLLDEPRGLPETYGN
                     RTSGWNAVPFGGAVFQRILPMLVAPTFPPPAGTVQAVPAATEEPGSRGTAAARTWLLRP
                     R"
     gene            complement(2852..5294)
                     /locus_tag="SMED_RS26685"
                     /old_locus_tag="Smed_5368"
                     /pseudo=""
     CDS             complement(2852..5294)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017271244.1"
                     /locus_tag="SMED_RS26685"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5368"
                     /product="penicillin-binding protein 1A"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKRIGFIFSIISAAMLAAFGIGAVYLSDLTRGLPDHRKLAEWEPA
                     VMTRFYAYDGTPLAEYARERRLFLPIAAIPERVKGAFLSAEDKSFYTHSGIDVLGVAKA
                     AWSNAMNAGSGQRLIGASTITQQLAKNFLLSSDRTLERKIKEAVLSIRIEHALGKDRIL
                     ELYLNDIYLGLGAYGIAAGALTYFDKSVSELTVAEAAYLAALPKGPNNYNPYRHAERAI
                     SRRNWVIAQMQRNGFVSAAEARDMMARPLGVKPRAAIPLMAEANYFAEEVRRQVAAEYG
                     EAALYTAGLSVRTTLDPALQAAALKALRAGLVEYDQMRGFRGPLAHIDLTGDWAAALEK
                     QETLADVKEWQLATVLSCSDEGVRIGLRNADPGSGRSSPGPVTGFIDSRSMRWALKLSA
                     TGKIRQADSLLQVLSPGDVIYVEEAESGFLLRQIPEVQGAIVAMGPHTGRVLASVGGFS
                     FAQSRFNRATQASRQPGSAFKPFVYAAALDTGYTPATLVADAPIAKPDGTGRIWRPKNY
                     DGKFGGPSTVRTGLEKSRNLMTVRLAQHLGMDVVRRIRPGVRPLR"
     misc_feature    5267..5285
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.02"
                     /tool="antismash"
     gene            5493..6377
                     /locus_tag="SMED_RS26690"
                     /old_locus_tag="Smed_5369"
     CDS             5493..6377
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970248.1"
                     /locus_tag="SMED_RS26690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5369"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_011970248.1"
                     /transl_table=11
                     /translation="MELPKLPLNALRAFEASARHCSFTRAGLELRVSQTAISHQVKALE
                     DLLGVKLFRRLPRGLALTDEGSALAPVMSDVFKRMCATVSRFEEGNFQEVVTVGVVGTF
                     AVGWLMERLSDFHDAHPNLDLRILSNNNRVDLAGDGLDFAIRFGDGSWHGTEAMHLIAA
                     PLSPVCSPLIAARLVEPADLARIELLRSYRSDEWAQWFQAAGSQSPVLRGMMFDTSLAL
                     AEAAARGFGAALLPVTMFEHYIETGRLVQPFEVTVAAGDYWLTWLKSRQFTRGMLAFKR
                     WLKEQFSGPSADL"
     misc_feature    6550..6565
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            6606..6752
                     /locus_tag="SMED_RS26695"
                     /old_locus_tag="Smed_5370"
     CDS             6606..6752
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018010586.1"
                     /locus_tag="SMED_RS26695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5370"
                     /product="DUF1127 domain-containing protein"
                     /protein_id="WP_011970249.1"
                     /transl_table=11
                     /translation="MNVARSLNNWRKYRQTVNELGRMTNRELDDLGINRADIRSVARAS
                     LAG"
     gene            complement(7088..7297)
                     /locus_tag="SMED_RS26700"
                     /old_locus_tag="Smed_5371"
     CDS             complement(7088..7297)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970250.1"
                     /locus_tag="SMED_RS26700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5371"
                     /product="hypothetical protein"
                     /protein_id="WP_011970250.1"
                     /transl_table=11
                     /translation="MAQGTYRPDDVAVMRSALDDWCAIHHISPTSREGVAVAVKILDLM
                     CDRSLTRQQLLKQLEHAPLAERIP"
     gene            complement(7356..8039)
                     /locus_tag="SMED_RS26705"
                     /old_locus_tag="Smed_5372"
     CDS             complement(7356..8039)
                     /EC_number="6.3.3.2"
                     /GO_function="GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970251.1"
                     /locus_tag="SMED_RS26705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5372"
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="WP_024311804.1"
                     /transl_table=11
                     /translation="MDIEDDDIPPAFASPPCLMHELDPAYAGLSSDRTNNVDVRRWRKS
                     ERARLIAERLAMAPDHRAMCEAQIVNRILAEIGDMRGLVVSLYWPFRGEPDLRPLMRQI
                     SDQGGECALPVVVQKEQPLEFHLWRPGDKLTRGIWNIPVPATPHSCTPDIVIAPVVGFD
                     ASGYRLGYGGGYYDRTLAGMTAKRRVMGVGFAQARIRTIYPQNHDVRMDVVVTDSTTDG
                     YSATR"
     misc_feature    8360..8375
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            complement(8442..9284)
                     /locus_tag="SMED_RS26710"
                     /old_locus_tag="Smed_5373"
     CDS             complement(8442..9284)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970252.1"
                     /locus_tag="SMED_RS26710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5373"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_011970252.1"
                     /transl_table=11
                     /translation="MDIELARTFLEIVSTGSFIRAAERLNVAQTTVSARVRTLEQLLGR
                     PLFVRNKGGASLTAAGEQFLRHAPMFVQLWQRTRQQVAVPAGHRAVLTVGSELTLAQPL
                     LLDWVRWIRQSLPDIALRVHVDVPRDLINQVASGMVDAAIMYAPQHRPGLEIDLLMEEK
                     LVLATSDPAMGLKKTSYVHTDWGPDFALHRDMNFPDVEPDLSFDFGPLALSYVLASGGC
                     GYFRMSAVKPHLAAGQLHLVPGMPQYSYPVYMVRSANADEGVLGPALAGLRAISEGNV"
     misc_feature    complement(9872..9886)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            10001..10621
                     /locus_tag="SMED_RS26715"
                     /old_locus_tag="Smed_5375"
     CDS             10001..10621
                     /EC_number="2.3.1.184"
                     /GO_function="GO:0061579 - N-acyl homoserine lactone
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970253.1"
                     /locus_tag="SMED_RS26715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5375"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_011970253.1"
                     /sec_met_domain="Autoind_synth (E-value: 2.8e-57, bitscore:
                     189.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVIAISAQPDLRAKQLLEQHHRLRARVFSDRLGWAVCVLDGLES
                     DAFDDLEPTYIIAVSDSGRVAGCARLLPAIGPTMVAEVFSSLLPDGRLKAHPQMIESSR
                     FCVETALAEGRAGGLVHEATLTMFAGIIEWCMANGYTEIVTVTDLRFERILARVGWPLQ
                     RLSKPKTIGPTIAVAGTLPVTADNVLRLRPSNYRSELAPPCRF"
     gene            10632..11609
                     /gene="trbB"
                     /locus_tag="SMED_RS26720"
                     /old_locus_tag="Smed_5376"
     CDS             10632..11609
                     /codon_start=1
                     /gene="trbB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004129936.1"
                     /locus_tag="SMED_RS26720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5376"
                     /product="P-type conjugative transfer ATPase TrbB"
                     /protein_id="WP_011970254.1"
                     /transl_table=11
                     /translation="MTQLRSHPRLVRKLQEALGDQLCVALDDASVVEIMLNPDGKLFID
                     RLGDGVALAGEMSSAAAEIVVGTVAHALQSEVDREQPIISGELPIGGHRFEGLLPPVVA
                     RPAFAIRRRASRLIPLEDYVRTGVMTEDQVSTIRSAISSRLNIIISGGTGSGKTTLANA
                     VIDEIVKTRPDDRLVILEDTAEIQCAAQNAVLLHTSDKVDMARLLKSTLRLRPDRIVVG
                     EVRDGAALTLLKAWNTGHPGGAATIHSNTAMSALRRLEQLTAEVSQQPMHEVIGEAVDL
                     IVSIERTPRGRRVRDVIRVERFAGGEYEIESDQLTEEQEARHVA"
     gene            11599..11979
                     /locus_tag="SMED_RS26725"
                     /old_locus_tag="Smed_5377"
     CDS             11599..11979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970255.1"
                     /locus_tag="SMED_RS26725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5377"
                     /product="TrbC/VirB2 family protein"
                     /protein_id="WP_011970255.1"
                     /transl_table=11
                     /translation="MLHKQALISVVAAASLLIAVVPALASSGGGGLPWEGPLEQIQESI
                     TGPVAGYIALAAVAIAGGMLIFGGELNDFARRLVYVVLVAGILLGATAIVGLFGATGAS
                     IGTPDEQIAKLGSNGGGEKAHV"
     gene            11972..12268
                     /locus_tag="SMED_RS26730"
                     /old_locus_tag="Smed_5378"
     CDS             11972..12268
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970256.1"
                     /locus_tag="SMED_RS26730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5378"
                     /product="conjugal transfer protein TrbD"
                     /protein_id="WP_011970256.1"
                     /transl_table=11
                     /translation="MSNSLGLQRNRVHRALSRPNLLMGADRELVLITGLAAVILIFVVL
                     TIYSALFGVAVWIVIVGFLRMMAKSDPLMRQVYLRHISYKPYYGATSSPWRRS"
     gene            12279..14732
                     /locus_tag="SMED_RS26735"
                     /old_locus_tag="Smed_5379"
     CDS             12279..14732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970257.1"
                     /locus_tag="SMED_RS26735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5379"
                     /product="conjugal transfer protein TrbE"
                     /protein_id="WP_011970257.1"
                     /transl_table=11
                     /translation="MVALKRFRATGPSFADLVPYAGLVDNGVLLLKDGSLMAGWYFAGP
                     DCESATDLERNELSRQINSVLSRLGSGWMIQVEAIRIPTVDYPSDDHCHFPDPVTRAID
                     AERRAHFAHTQGHFESKHALILTYRPLESRKAALSKYIYSDEESRKKSYADTVLFVFKN
                     AVREIEQYFANTLSIKRMETRETVKRGGERVARYDELLQFVRFCITGESHPVRLPDIPM
                     YLDWLATAELEHGLTPKVENRFLGVVAIDGLPAESWPGILNSLDLMPLTYRWSSRFIFL
                     DAEEARAKLERTRKKWQQKVRPFFDQLFQTQSRSVDQDAMLMVAETEDAIAQASSQLVA
                     YGYYTPVVVLFDDDRNTLQEKAESVRRLVQAEGFGARIETLNATDAYLGSLPGNWYCNI
                     REPLINTSNLADLIPLNSVWSGNAVAPCPYYPPNSPPLMQVASGSTPFRLNLHVDDVGH
                     TLVFGPTGSGKSTLLALIAAQFRRYDRAQIFAFDKGNSLLSLTLAAGGYHYDLCGDDAE
                     ERNALAFCPLSELKSDADRAWATEWIEMLIALQGVIITPDHRNAISHQVSLMASATGRS
                     LSDFVSGVQMREIKDALHHYTVDGPMGQLLDAEEDGLTLGALQTFEIEQLMNMGERNLV
                     PVLTYIFRRIEKRLDGSPSLIILDEAWLMLGHPIFRSKIREWLKVLRKANCAVVLATQS
                     ISDAERSGIIDVLKESCPTKICLPNGAAREPGTREFYERIGFNERQIEIVSIAIPKREY
                     YVATPEGRRLFEMALGPVALSFVGASGKEDLKRIRALKSEHGRDWPIHWLETRGVQDAA
                     AILKK"
     gene            14707..15507
                     /gene="trbJ"
                     /locus_tag="SMED_RS26740"
                     /old_locus_tag="Smed_5380"
     CDS             14707..15507
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trbJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018210390.1"
                     /locus_tag="SMED_RS26740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5380"
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="WP_011970258.1"
                     /transl_table=11
                     /translation="MPQRYSKNSWFAGSMVASMTIVAALPVHAGTATGAATEWTQVLNN
                     AELVSLVGQSGEQIQNQLTKISQLSQQIETQLNIYRNLLQNTAALPSHMWGQVENDLNR
                     LRSIVDQGQSIAFSMGNADDVLQQRFASYADLRTNLPANETFSATYQTWSDTNRDTIAS
                     TLKAASLTADQFESEESAMSSLRSMSETADGQMKALQIGHQIAAQQVAQMQKLRGLVSQ
                     QMTLMGTWLQTEQTDKDLAQARREKFFRAEVKSIPEGQKMEPRW"
     gene            15504..15704
                     /gene="trbK"
                     /locus_tag="SMED_RS26745"
                     /old_locus_tag="Smed_5381"
     CDS             15504..15704
                     /GO_process="GO:0009292 - horizontal gene transfer
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trbK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970259.1"
                     /locus_tag="SMED_RS26745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5381"
                     /product="entry exclusion protein TrbK"
                     /protein_id="WP_011970259.1"
                     /transl_table=11
                     /translation="MSRAVLVALLLAVAVASSAATVLIINPRDTLKSSLTEQQRSARER
                     FFGTGKELPPIKDGQEMRPRW"
     gene            15698..16906
                     /gene="trbL"
                     /locus_tag="SMED_RS26750"
                     /old_locus_tag="Smed_5382"
     CDS             15698..16906
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trbL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970260.1"
                     /locus_tag="SMED_RS26750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5382"
                     /product="P-type conjugative transfer protein TrbL"
                     /protein_id="WP_011970260.1"
                     /transl_table=11
                     /translation="MVKVTRPFLIAGLLCIAYSAPAFAQEGHVLTELENQVSSAAKGWE
                     TTIMNAARSLFWILAAIEIGIAAVWLATQAASLDSWFAELVRRIMFVGFFAFILEQGPT
                     FARAVVDSLFQIGADSDSASPAEVFDAGIRVASQMSQQVQFGVFEDNALAIAAVLAMGV
                     VVICFSLVAAIFVSVMVEMYVGLLAGMIMLGLGGSSFTKDFAVRYLIYAFGVGMKLMAL
                     VMIAKIGSSVLLGLAQAPTASSDKFVTALAIAGISVVVFIIAMYVPTILQGVVQGASVS
                     GGMEAIRHGGQAASFAAGAGFLAAGAAGAGFEAGKFARAAGSSVAGAALRSVGAGIGSA
                     GRAVGSAAKEKAIGAPGAYAGSILGLANAKLDEQRSGLSESLPSATKSRNQEAKEDGSK
                     PHA"
     gene            16884..17546
                     /locus_tag="SMED_RS26755"
                     /old_locus_tag="Smed_5383"
     CDS             16884..17546
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018482029.1"
                     /locus_tag="SMED_RS26755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5383"
                     /product="conjugal transfer protein TrbF"
                     /protein_id="WP_011970261.1"
                     /transl_table=11
                     /translation="MAVNRTPENPYLAARQEWTERYGSYVKAAAAWRVVGILSLALALV
                     GFSYALYLSTQVRLVPYIVEVDRLGTSVASGFPEQIEYADARVVRATLGNFVTSFRSVT
                     PDAVVQKQYIDRTYALLRTSDPSTQKINDWFRSNSPFEKARSSTVAIEVNNIVALSNQT
                     YQIDWTEYERDRKGKETGTRRFRGIATVALTAPQDEATIRLNPIGLYVTDFDWTAQL"
     gene            17563..18375
                     /gene="trbG"
                     /locus_tag="SMED_RS26760"
                     /old_locus_tag="Smed_5384"
     CDS             17563..18375
                     /GO_process="GO:0009291 - unidirectional conjugation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trbG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970262.1"
                     /locus_tag="SMED_RS26760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5384"
                     /product="P-type conjugative transfer protein TrbG"
                     /protein_id="WP_011970262.1"
                     /transl_table=11
                     /translation="MQKTRLLTVAGCLAGLVFVSGAQAQNMTTNEVKGTKISSKWRGTP
                     GLVTKGPDGKVIFLFGETQPSVVCSPLQVCDIELQGGEIVRDVLVGDTVRWKVEPATSG
                     ATGGQAIHLVVKPSEPNLLTSMVVTTSRRTYHIQLKSHPSQYMARIGFEYPEDVSTKLS
                     DINARLEAGGIPGAAPDKLDFSYSISGQASWKPKRVYSDGVKTYIHFPRSIFGQDAPVL
                     FVVSGGQNRIVNYRMKNDMMIVDYAVDKAILVSGVGWRQQKIIIRRGS"
     gene            18379..18819
                     /gene="trbH"
                     /locus_tag="SMED_RS26765"
                     /old_locus_tag="Smed_5385"
     CDS             18379..18819
                     /codon_start=1
                     /gene="trbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970263.1"
                     /locus_tag="SMED_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5385"
                     /product="conjugal transfer protein TrbH"
                     /protein_id="WP_011970263.1"
                     /transl_table=11
                     /translation="MQNLLSTVIAAALLSGCQTADQGLRPSSDAGAVTGPAASAIAGDM
                     VSRLAEQIGPATATTTIRMDKDTSEFAIALEAALKGWGYTVVTDKKLVRGIKPVELAYA
                     AESFDGQILARLSTPSIAFGRAYTPTGAGAMPASPLSILQRN"
     gene            18832..20124
                     /gene="trbI"
                     /locus_tag="SMED_RS26770"
                     /old_locus_tag="Smed_5386"
     CDS             18832..20124
                     /codon_start=1
                     /gene="trbI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011970264.1"
                     /locus_tag="SMED_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Smed_5386"
                     /product="IncP-type conjugal transfer protein TrbI"
                     /protein_id="WP_011970264.1"
                     /transl_table=11
                     /translation="MVQSLQLGASSHADDQKAMRRLNRLPIFVAITVIVLFFAVVVIGL
                     SWRGVSLKRGDDTQSISNTPATSFGEQLKRGVTDGIIGEPVEREAFQPTPVVHKVDTQE
                     SVVERRPGERKERRPKLESEEEWKARLKREQDEQYIREAHRQRMARLQAHATALDSPLK
                     VDVSDIKNSTNHANTRQSRNLEAKGASDLHAAAMKSGLISQQVDPNGQISKEEFFNKEI
                     KDLGYLPNQVVPQLSPYELKRGSVIPATLITGLNSDLPGRIAAQVSQNVYDSATGYRLL
                     IPQGAKLLGRYDSKLSFGQERVLVVWTDLIFPNGSTLQIGGMAGTDAEGYGGFKDKVDR
                     HLWRTFGSAALVAIIGTGIDMSLPESSTLATQDTASDAARRNFAESFGRVAEQTISKNL
                     NVQPTIRIRPGYKFNILVDQDIVFPSVYNGH"
ORIGIN
        1 ctttcagcgt tgcgcccgcc aggatcgggg aaaacagctt aaacctgggc gaagaccctg
       61 gcttctgaac attatcgggt ggaggcggaa caatcatttc ggggggcgtc agatgcagtt
      121 gctcattttt cgaagcttat gtgcttataa aaagagcgaa gcaataggcc gatcggattt
      181 ccgtgtcgtt ccgatcgata ttttggaggc cggaagttgg cacgcaaatt gcttctcaaa
      241 ggcgaaacag ttgacacggg tgcagcttgg acgtcttcga catctcctcc gctctgatct
      301 ggctcgctct tggattgagc ggccccgcgt ttctcacggc ttttgccgat cagccacgtg
      361 gctggaaatc cgccgccgaa acgactgtcg ggaccagtgt tttcgtcgca gcattgggcc
      421 tatgtctttc tgccggagcc tttgtcgcga ccgcggtcgc tgctcccgta gcactcgccg
      481 tcgccacaat gtttcgacga aactgccaac ggctgccgat gttggcggtc tcgattctct
      541 gcctgggtat ctatctctaa agccccatat agccgccgat tgcaggcgct tcagtcaggc
      601 ggatgccgag tcgcctcgtc gccgggtgcc gacggttgaa tagtttcaat tcgacttgct
      661 tcgggctggc cgtcgggctc gatcggctcg gagagcgtcc cgatcggctt cgccgccaaa
      721 gccttcagat cttctgcgag cccggcaagc tgcgcggcaa agtccagaag gtccgaagcg
      781 gcgcactgcg ccgcggtttg caggaggtcc ggggccgttg ctgcatcgtc ggcgctaacg
      841 ttttcgcggt cgctcatatc catttctcat tgctggagtc gcaactaaga tagacccgct
      901 ccgccgtggt gaaaattggg acaaaaggcc gatgtccgca cctcggcggg aagcggagga
      961 ccgtcggccg tctcgctcgg atcggcggct gacagccatc aaaccacgag cgcccagtaa
     1021 accacgggcg cccagtaaac cacgggcgct cagtgccggg ccactcacca atctggctta
     1081 atccgtttat ctgggccgga gcagccaggt tcgtgcggct gccgtccctc gcgaaccggg
     1141 ttcttcggtc gcggcgggaa ccgcttggac agtgcccgcg ggcggcggaa aggtgggcgc
     1201 aacgagcatt gggaggatgc gctggaatac ggcgccgccg aacggcaccg cattccagcc
     1261 cgaggttcgg ttgccatatg tctcgggcag tccgcggggc tcgtccaaaa gggtgagcag
     1321 caggtatctg ggattgtccg ccggtacgat acccatgaaa gatgtgacgt tgagctccct
     1381 ggaatagcgg cccccgacca ctttctcggc tgtgccggtc ttgccgccga ttgcgtaacc
     1441 gggaacattg gctctcgttg cagacccgac agcggtgttg aggcgcaaaa gatggcgaat
     1501 tgcctcgctg gtgtccgacg acacgagatc ctccgctatc gtccgttcgg aaacggggct
     1561 gtcctttatg aaagtgggcc tgatcagcct gccgccgttc gccagagcgg ccaccgcagt
     1621 gctggcctgc agcggcgtaa cggcaatccc atggccgaat gagaccgttg ccgtcgccac
     1681 ctcactccac gaggatggca gcagcggtgc ggcgctctcc ggcagttcgg ttgcaagcgg
     1741 cgacagggct ccgaagcgtc cgaggaatgt cctcgacgct tccggtccga gggccaacgc
     1801 cattttcgcc atgacgatat tggaggagtg cacgaatgct tcgggaatgg tcagcggtct
     1861 gtacttgccg cgataatcat ggatgcgcat cctcccgaaa ttcaaaggct tgctcgcatc
     1921 caccaccgat tcgagattaa accggcccga ttccagagcc attgccgtcg tcagagcctt
     1981 gaaggtcgat cccatctcga agacgccagc agtaacgcgg tttattcggt ctggcttgaa
     2041 tgcattctcc ggattgttcg gatcgaagtc cggataggag gcgagcgcga gaacttcgcc
     2101 attggtgacg tcgagcagga gcccggcacc cgcggcagcc ccgaatttcg tgatggcctt
     2161 gccgagctcc tgctccagtg cgtattggac gcgcaggtcg atcgacagct cgatccgttg
     2221 gagttcacgt cccttgagtt ccagcccggc accgcgcagg tccgcgagcc agtttgcatc
     2281 aatccacttt tcaatacccg caatgccccg attgtcgatg tccacggcgc caaggatatg
     2341 ggcagccaat gagccgttcg gatagagccg tcggttttcg gggcgaaagc cgatcgctgc
     2401 caatccggaa tcgatgaccg cctgctgctt gtccggagtt atctgccgct tgatccaggt
     2461 gaaggcgtct ttgctacgca ggcgcgaatg gagctcccgg gcatcgagtt cggggaaaat
     2521 cccggtgagt ttttcaaccg cctcgtccag gtctgggatc gaccgcggct cgataaagag
     2581 cgacgcgatg ggtatatcgg tcgcgagcag ctccccgttt ctatcgacga ttgcgggccg
     2641 gccacctgga gcccggtcat aggtgatgct gatcccgtgg ctcgcttcct gctccattcc
     2701 aaactggacg agtcgcagaa aaataccggt gaatatggca gcaaacgctg ccatgatgca
     2761 gatgatgcgc acccgtctgc tgtgtgccct gctccgaagg gtgaaggcgt gcttcctcat
     2821 ttggatcctc ggcgagtaag agacggcagg ctcaatagag gccctgcggg gcggtcagta
     2881 gctgcttgcg cagcgctgcg ggcatgtcct cgtcgccgtt tgctccgaac ccgtctatga
     2941 cgggacactc ggtcgaacac ggcgcggttc ccggcttgaa tgcctcgacg atcccgccgg
     3001 gatctgcaga agcggaaagc ctgcctgtgc ggcgatccac ggttgcgaag gtcaagccct
     3061 ctggaacggg gaaatcgatg gcagctttgc cgcgcagtgc cgtcttcatg aaatcgatga
     3121 agatcggggc tgccagtcca ccgcccgttt cgccatagcc catcggcttc ggcgtgtcgt
     3181 atcccatgaa aacgccggtc acgagtgtcg gggtgtagcc gacgaaccag acgtccttct
     3241 cgtcgttcgt ggtgccggtc ttgccggcga ttggaacccc gagctgcgcc accttgtgcg
     3301 ccgtcccatg ttccacaaca ccgcgcagca tcgatgtcac ctgataggcg gtcatcgggt
     3361 cgagcacctg ctcgcgggta tcgcgaagca ccggctcttc ctgatgcttc caacttgcgg
     3421 cgttgcattg atcgcaatcg cgctggtcgt gacggaagat cgtgcggccc tggcggtcct
     3481 gaatgcgatc gatcgccgac ggcgtcacgg agcgtccgcc attggcaagg accgcatagg
     3541 ccgcaacgag ccgcatcagt gtcgtttcgc cggctccgag cgacatcggc aggtagggtg
     3601 cgagtttatc gtagaggccg aacgcctggc cgtattcggc gaacgacgtc catgccgaga
     3661 tgttgcgcga ggcgaacggt catcaggttg cggcttttct ccagccccgt gcgtacagtg
     3721 gacggaccgc cgaattttcc gtcgtagttc ttgggtctcc atattcggcc tgtcccgtcc
     3781 ggcttcgcaa tgggcgcatc cgcgaccagc gtcgccggag tgtagccggt atcgagagcg
     3841 gccgcgtaaa cgaacggctt gaaggctgaa ccgggctggc gggatgcctg cgtcgcgcga
     3901 ttgaaccgcg actgcgcgaa ggagaagccg ccaacgctcg ccagcacgcg ccccgtatgc
     3961 gggcccattg ccacgatcgc accctgcact tccggtatct gccgcaggag aaaaccactt
     4021 tccgcctcct cgacataaat gacgtcgcct ggcgagagaa cctgcaaaag ggagtccgcc
     4081 tgccttattt tgcccgtggc ggaaagtttc agtgcccagc gcatggacct gctgtcaatg
     4141 aagcccgtca caggacctgg cgacgatcgc cctgaaccag gatccgcatt tctaagcccg
     4201 atccgcacgc cctcgtccga gcaggagagc accgtcgcga gctgccactc cttcacatcc
     4261 gccaaggttt cctgtttctc caaggcggcc gcccagtctc cggtcagatc gatatgggcg
     4321 agcggccccc ggaatcctcg catctgatcg tattcgacga ggccggcccg caacgccttg
     4381 agcgctgccg cctgaagcgc cgggtcgagc gtcgtgcgta ctgaaaggcc ggcagtatag
     4441 agcgccgcct cgccatattc cgcggcaacc tgccggcgga cttcctcggc gaagtagtta
     4501 gcctctgcca taagggggat cgcggctcga ggctttacgc ccagaggtct cgccatcata
     4561 tcacgtgctt ccgcggcgct gacgaagccg ttacgttgca tctgggcgat cacccagttg
     4621 cgccggctga tcgcgcgttc ggcatgtcga taagggttgt agttgttggg tcccttcggc
     4681 agagcagcga gatacgctgc ctcggcaacg gtcagttcgc tgacggattt gtcgaaatag
     4741 gttagcgcac cggcggcaat gccgtaggct ccgagcccga ggtagatgtc gttcaggtaa
     4801 agttccagga tcctgtcctt accgagtgcg tgctcgatcc gaatggacag caccgcctcc
     4861 ttgatcttgc gctcgagggt gcggtccgaa gaaagcagga agtttttggc gagctgctgc
     4921 gtgatcgtgg aggcgccgat caatcgttga cctgatccgg cattcatcgc gttggaccag
     4981 gcagccttgg cgacacccag gacatcaatt cccgaatgcg tatagaagct cttgtcttcc
     5041 gccgagagaa aggcgccctt cacgcgctcc gggatcgcgg cgatgggcag gaacagacgc
     5101 ctttccctgg catactcggc aagcggcgtt ccgtcatagg cgtaaaagcg cgtcatgacc
     5161 gccggctccc attccgcaag tttgcggtgg tccggcaggc cccttgtaag atccgagaga
     5221 taaacggcgc cgataccgaa cgcggccagc atcgcggccg atatgatgct gaagataaaa
     5281 ccaatgcgct tcatgccgat cccgacagct tcatgccaga caaaaacttg gcacaggaat
     5341 aggcgccgcc gtcgcggaag cggcgaaagc ggtgactgaa agccctgtgg cgacttgaac
     5401 tgcggcgaag atgacagaag cgtcggcact cgacaaacga gcaatattgc gggtaggcat
     5461 gaatcagatt tggccttagc gaaactgatt ccatggaact ccccaagctg cccctcaatg
     5521 cactacgtgc cttcgaagca tcggcgcgcc actgcagctt cacgcgtgcc gggctggagc
     5581 tacgggtttc gcagacggca atcagccatc aggtgaaggc gctcgaggat ctgctcggcg
     5641 tcaagttgtt ccggcgattg cccaggggcc ttgcccttac cgatgaaggc tcagcccttg
     5701 ccccggttat gagcgacgtg ttcaagcgca tgtgtgcaac cgtcagccgc ttcgaggaag
     5761 ggaactttca ggaggttgtc accgtaggcg ttgtcggcac cttcgcagtc ggatggctga
     5821 tggagcggct atcggacttt catgatgcac atccgaacct cgacctccgc attctgagca
     5881 acaacaaccg cgtcgatctg gctggcgacg gcctggattt cgcgatccgg ttcggggacg
     5941 gctcatggca cggcacggag gcgatgcacc tgatcgccgc gccgctatcg ccggtctgct
     6001 cgcctttgat tgccgcccgg ctggttgaac cggccgacct tgcccgaatc gagctgctgc
     6061 gttcgtatcg gtccgatgag tgggcgcaat ggtttcaagc ggcgggcagc cagtctcccg
     6121 ttctgcgcgg catgatgttc gatacctcgc tggcactggc ggaagcggcc gcgcgaggct
     6181 tcggtgcggc cctcctgccg gtcaccatgt tcgagcacta tatcgagacg gggcgtctgg
     6241 tgcagccttt cgaggtcacg gtagcggcgg gtgactactg gctcacatgg ctgaagtcac
     6301 gccagttcac cagaggcatg ctggcattca aaaggtggct gaaggagcag ttctccggtc
     6361 cttccgccga cctgtagaag ccgggtggcc ggagatcgtc ttggcgcaaa agccaaggca
     6421 cctttttgtg tatcgattac ctgccgcaga ctgatgggac cagggaccat tgcacgcggt
     6481 gcatgggtgg cgtgatgcaa tggcgctacc gctgcgtcgg taggaaacct atattcgcct
     6541 tatcgaacga cgccggagcc gaacaaggtt gctgacgtcc acagacctca ggaaagggga
     6601 tcatcatgaa cgtagcacgc tccttgaaca actggcgcaa gtaccgtcag acagtgaacg
     6661 aacttggccg catgaccaac cgcgaactgg acgacctcgg tatcaaccgg gccgacatcc
     6721 gcagcgtcgc ccgcgcttcg ctcgctggct gacagcgcaa taaaccatcg cttcgcaagc
     6781 gcccgcccga tgaggcgggc gtctttgcgt tcgggcatct gctattaagc cttgcacttc
     6841 gtgcattgct gcattgcagc aaaatacata gaaactgacc gcaaccattg tatgattgtt
     6901 ttcaacgaag cgatgcacct cctcccgcag agcttcgtga ttcaggcggc ccactcctcc
     6961 tcccagggac gtctgaagga ccagcggcac tcctcctccc tgtcgctgat cggttctttt
     7021 aggaaagcct gccgcacctc ctcccgcggc aggctttttc gtttctggcg tccacgtcaa
     7081 cggtaggtca tggaattcgc tcggcaaggg gagcgtgttc gagttgcttg agcagttgct
     7141 gccgggtcag cgaacggtcg cacatcaggt cgaggatctt cacagcgacg gcgacaccct
     7201 ccctgctggt aggcgagatg tgatgaattg cacaccaatc gtccagcgcc gaccgcatga
     7261 cggcaacgtc gtccggccta taagtcccct gggccatgtt atcctccctc gaacgcaacg
     7321 aagtaagcgt ttcttgatca cccaacgtgt gcaaatcacc gcgtggcgct gtaaccatca
     7381 gtggtagagt cggttaccac gacgtccatt cgaacgtcgt ggttctgtgg gtatatcgtt
     7441 cttattcttg cctgcgcgaa gccaacgccc atcacccgcc gcttcgctgt cattccggcc
     7501 agcgtccggt cgtaatagcc cccgccataa ccgaggcgat agcccgatgc gtcgaagccc
     7561 acgaccggtg cgatgacgat atccggcgtg catgaatgag gcgtggccgg aacgggtatg
     7621 ttccagatgc cacgggtcag cttgtccccc ggccgccaga ggtggaattc cagaggctgc
     7681 tccttctgaa caaccacggg aagcgcacat tcgccgcctt ggtcggatat ttgccgcatc
     7741 aacggtctga ggtcgggttc accccgaaaa ggccagtaca aactgactac aaggccgcgc
     7801 atatctccga tttcggcaag tatgcgattg acgatctgcg cttcgcacat tgcccgatgg
     7861 tcgggagcca ttgccaggcg ttcagcgatt aggcgagcac gttcgctttt ccgccaccgc
     7921 ctgacatcga cattgttcgt ccggtcggat gacaggccgg cataggccgg gtcgagttcg
     7981 tgcatcaggc atggcggcga ggcgaaagcc gggggaatat cgtcgtcctc gatgtccatg
     8041 cttgtcgctt ccttttcaat ctcgctcaag gccatgttca agccctttta gggcggcacc
     8101 acggaaccga atgccgtgtc ggacgcgcgc tctaggctgc ggccgtgacc tcagcgctgg
     8161 cagatttgga ccttcgttcg tgcatcgccg cttccattca gtctacgcaa cattgccggt
     8221 caagctcagc cttgcacgca cctcgaggga attgatgaac cgcctctctt catcgaaaag
     8281 tcggtggttt ggcccgatct gaataataca gggttctctc gtaccaagat gccaaggccg
     8341 ttccccgctg acaaacgaat tgaattgctg tttgaccgca aattttttgc tcttattttg
     8401 accggcgtag cgtaacggaa agctgcctac gtgcgcctgg atcacacgtt gccttcggag
     8461 attgcccgta atcccgcaag tgccggcccc aagacaccct catcggcgtt cgcggatcta
     8521 accatataca ccggatagga gtattgcggc attccaggca ccaggtggag ctggcccgcc
     8581 gccagatgcg gcttcactgc actcattctg aaatagccac agccgccgct cgcaagaaca
     8641 tagctgagcg ccagggggcc gaaatcgaac gagaggtcag gttcgacatc cggaaagttc
     8701 atgtcgcgat gcagcgcgaa gtcaggcccc caatctgtgt gaacatagct tgtcttcttc
     8761 aggcccattg cgggatcgct tgtcgcaagc acaagctttt cttccatcag cagatcgatt
     8821 tcgaggcccg ggcgatgttg aggtgcatac atgatcgccg catcgaccat tcccgaagcc
     8881 acctggttga tcagatcccg tggcacgtcc acatgtacgc gaagcgcgat atccggaaga
     8941 gactgccgga tccatctgac ccaatctagc agcagtggtt gcgcaagcgt gagttcgctg
     9001 ccgaccgtca gcaccgctcg gtgtccggcc ggcaccgcga cctgttgacg cgtgcgctgc
     9061 cagagttgaa cgaacattgg cgcgtggcga aggaactgct cgccagccgc ggtgagagac
     9121 gctccgccct tattccgaac gaatagtggc cggccgagca gttgttcgag ggtgcgaacc
     9181 cgcgcgctca ctgtcgtctg agcaacattc aagcgctcgg cggcgcgaat aaaactgccc
     9241 gtcgagacga tctccaagaa agtgcgggcg agttcaatat ccattgaaag acagcataaa
     9301 tactgctctt aagcgccgat caaattcctt tgctcaatac taacgaggcc gtgagctcag
     9361 gtaaatccat caatgcgcac agtgtcagtc caccagggct tggccggggc agcttgctgt
     9421 tgtcagccaa gtgtgagaat gccgtttcag ccgggctcgg catcttttga tgagcagccg
     9481 gcttctcaaa tcggctgcct ctgcgaggca tcttgatctg cggattggcg attggtcctg
     9541 atcattgttc tggctcgcag cattttgagc atctcgaagc cattatacct gcgtagaggg
     9601 tggcgcggct ggtgcagcac ccgctcggcg ggtctggcct cgattggacg cccggcacac
     9661 agaatgaaac ccggtcggta gcttccgcta tcatgcccat gtggtgcatg gcaactatga
     9721 cgctggtcgt caactcctcg tacagtttgt gcaaagcgaa atgctccgcg gcggatctca
     9781 gatcgggcgc catggtcggt tcgtccgcca tgacaagttt cggcgatacc gcgaagcgca
     9841 agtgctcccc acgacactct ggcgcatgcc gcccgagaac ttgtgctacc gccatcgtcc
     9901 ttttggcggc tacctcaagc taccttgtcg gattcaacaa ctgcaaagcg attctgatcc
     9961 gtgctcatct ttgcgtcgaa tcgaaacgac ggagaaaagc atgcaggtaa ttgcgatttc
    10021 cgcgcagccg gatcttcgcg cgaagcaact tctcgaacag catcacaggc tccgagcgcg
    10081 ggtcttttcc gatcggttgg gctgggcggt ctgcgttctc gacggactgg aatcggacgc
    10141 ttttgatgat ctcgagccaa cctacatcat cgctgtctcg gacagcggcc gggtcgcagg
    10201 atgcgccagg ctccttccgg caatcggccc aacaatggtg gctgaggtct tctcctcact
    10261 tctcccggac ggacggctga aagctcaccc ccagatgatc gaaagctccc gcttctgtgt
    10321 cgaaacggct ctagcggagg gaagggcagg cggcttggtc catgaggcga cgctgactat
    10381 gtttgcgggc atcatcgaat ggtgcatggc gaatggttac accgagattg tcacggtgac
    10441 cgatctccga tttgagcgga tcctcgcccg cgtcggatgg ccattgcagc gtttgagtaa
    10501 gcccaagacg atcggtccca cgatagccgt ggccggcacg ctgccggtca cagcggacaa
    10561 cgttctcagg cttcgccctt ccaactatcg ctctgaactt gcccctccct gccgatttta
    10621 aggagagatc cgtgacccag cttcgttctc acccccgact cgtccgcaag cttcaggagg
    10681 cactcggcga tcagctctgc gtcgccctgg atgacgcgag tgtcgttgag atcatgctca
    10741 atccagacgg aaagttgttc atcgaccggt tgggcgacgg tgttgcgctt gccggggaaa
    10801 tgtcatcagc tgctgctgaa attgttgtcg gtacagtggc gcatgcgctc caatccgagg
    10861 tcgacaggga acagccgatc atctccggtg agttgccgat cggtggtcac cgtttcgagg
    10921 ggctccttcc cccggtcgtg gcaaggcctg cctttgcgat tcggcgccgc gcctcacgcc
    10981 tcatccccct cgaagactat gtccgcaccg gggtgatgac cgaagatcaa gtctcgacta
    11041 tccgaagtgc aatttcctcg aggctcaaca tcatcatctc cggagggacc ggttccggca
    11101 agacgacgct tgcaaatgct gtcatcgacg agatcgtcaa aaccaggccg gatgatcgcc
    11161 tcgtgattct tgaagatacc gcggaaattc agtgcgcggc ccagaacgcc gttcttctac
    11221 ataccagtga taaggtcgac atggcgcggc tccttaagag caccctgcgc ttgcgtcccg
    11281 acaggatcgt cgtgggcgaa gtgcgcgacg gcgcggccct aacgctactc aaggcctgga
    11341 acaccggtca tcccggtggg gcggctacga ttcactccaa caccgccatg tcggcgctcc
    11401 gccgtcttga acagctgacg gccgaggtaa gccagcagcc aatgcacgag gttattggag
    11461 aagccgtcga tctgattgtt tcgatcgagc gcacgccccg cgggcgacgc gttcgcgacg
    11521 tcatccgcgt cgagcgtttc gccggcggcg agtatgagat cgaatccgat cagctcacgg
    11581 aagaacagga ggcgcgccat gttgcataag caagcactca tcagcgttgt tgcagccgcc
    11641 agccttctca tagctgtggt gccggcgctt gcgagttcag gtgggggcgg tcttccgtgg
    11701 gaagggccgc tagagcagat ccaggagtcg atcacgggcc cggtcgctgg atatattgcc
    11761 cttgcggccg tcgccatcgc tggcggaatg ctcattttcg gcggcgagct gaacgatttc
    11821 gcgcggcgac ttgtgtacgt cgttctcgtg gctggcatcc tgctcggcgc cactgccatc
    11881 gttggtctgt tcggcgcgac tggcgcctcg atcgggactc cagacgagca gatcgccaag
    11941 cttgggtcga acggaggagg ggagaaagct catgtctaat tccctcggtc tgcaacgcaa
    12001 ccgcgttcat cgcgcgcttt cgcgcccgaa cctcctgatg ggcgcggacc gggagctggt
    12061 tttgatcacc gggcttgcgg ccgtgatcct gatcttcgtc gtgcttacga tttattcggc
    12121 gctcttcggt gtcgcagtct ggatcgtgat cgtgggcttt ctcaggatga tggcgaagtc
    12181 cgatccactg atgcgacagg tctatttacg gcacatttcc tacaaaccct actatggggc
    12241 gactagttcg ccgtggcgcc gatcctgagg tgtcggcaat ggtagccctc aaacgtttcc
    12301 gtgcgaccgg tccgtccttc gccgatctgg tcccttatgc cggcctggtc gataatggcg
    12361 ttctcctcct gaaggacgga agcctgatgg ccggctggta ctttgctgga ccggactgcg
    12421 aaagcgccac tgacctcgaa cgcaatgaac tatcgaggca gatcaattcg gtcctgtcgc
    12481 gccttggaag tgggtggatg attcaggtcg aggcgatccg cattccgaca gtcgactatc
    12541 catctgacga ccactgccat ttccctgacc cggtaacgcg tgcgatcgat gccgagcgcc
    12601 gcgcgcactt cgcacacacg caggggcact tcgagagcaa gcacgcgcta atactgacct
    12661 atagaccgct tgagtcgagg aaggctgctc ttagcaaata catctactcg gatgaggaga
    12721 gccgcaagaa gtcctacgcg gacacggtac tatttgtctt caagaacgcc gtccgcgaga
    12781 tcgagcagta tttcgcgaac acgctttcga tcaagcgaat ggaaacgcgc gaaacggtta
    12841 agaggggcgg ggagcgggtt gcccggtatg acgagttgct ccagttcgtg cggttctgca
    12901 taacaggcga gagtcacccc gtccgcttgc cggatattcc gatgtatcta gactggcttg
    12961 cgaccgccga gcttgaacac gggctgacgc cgaaggttga gaaccgcttc cttggcgtcg
    13021 ttgctataga cggcctgccg gcggaaagct ggccagggat cctgaacagt cttgacctga
    13081 tgccgctcac ctaccgatgg tcatcgcgct tcatctttct cgatgccgaa gaagcccggg
    13141 cgaagctcga acgcacacgc aagaaatggc agcagaaggt gcggccgttt ttcgaccagc
    13201 tgtttcagac gcaaagccgc tcggtggatc aggacgccat gctgatggtg gccgagactg
    13261 aggatgccat cgcccaagcc tcgtcgcagc tggtcgccta tggctactac acgcctgtgg
    13321 tcgtgctgtt cgatgacgat cggaacacgc tgcaggagaa ggccgaatct gtgcgccgac
    13381 tggttcaggc cgaaggattt ggtgcgagaa ttgagacact caacgcgacc gacgcttatc
    13441 tcggcagcct gccgggcaac tggtactgca acatccgtga accgctgatc aacaccagta
    13501 acttagctga tctcattcct ctcaattcgg tctggtccgg caacgccgtt gcaccatgcc
    13561 cctactatcc gccgaactcg cccccactga tgcaggtcgc cagcggttcc acgccatttc
    13621 ggctgaacct gcacgtcgat gatgtcggcc atacgctggt cttcggcccg acggggtcag
    13681 gcaaatctac gctgctggcg ctgatagcgg cgcagtttcg ccgttatgac cgcgcccaga
    13741 tctttgcttt tgacaaaggg aattcgctgc tttctctaac gcttgcagcg ggtggctatc
    13801 actatgatct ctgcggcgac gatgcggaag agaggaacgc tctggccttc tgccctctat
    13861 ccgaactgaa aagtgacgct gatcgggcgt gggcgacgga atggatcgag atgctgatcg
    13921 ccctgcaggg cgtcatcatc acccccgacc atcgcaatgc catttcccat caagtctcac
    13981 ttatggccag cgcgacgggg cgctcgctgt cggatttcgt tagcggcgtt cagatgcgcg
    14041 agattaagga cgcacttcat cactacaccg tcgacggtcc gatgggccag ttacttgatg
    14101 ctgaagagga tgggctgacg cttggcgcct tgcaaacttt cgaaatcgag cagctcatga
    14161 acatgggtga gcgcaacctg gtgcctgtgc tcacctatat cttccgccgg atcgagaaac
    14221 gcctcgatgg ctcgccaagc ctgatcattt tggatgaagc atggctcatg ctcggccatc
    14281 cgattttccg tagcaagatc cgcgagtggc tgaaagtgct tcgcaaggcg aattgcgccg
    14341 tggtgcttgc tacgcagtcg atctcggacg ctgagcgctc cggcatcatt gatgtgctca
    14401 aggaatcctg ccccacaaag atctgccttc caaacggcgc tgctcgggag ccggggacgc
    14461 gcgagttcta cgaacggatc ggcttcaacg aaagacagat tgagatcgtt tcgatcgcca
    14521 ttccgaagcg agagtactac gtcgccactc cggaaggccg acggcttttc gaaatggctc
    14581 ttggtcccgt ggcactcagt ttcgtggggg catcggggaa agaggatttg aagcgcatcc
    14641 gcgcactcaa atccgagcat ggccgcgatt ggccaatcca ctggcttgaa acgagaggag
    14701 ttcaagatgc cgcagcgata ctcaaaaaat agttggttcg ctggttccat ggtcgcttcg
    14761 atgacaatcg tcgctgccct gccggttcac gccggcacgg ctaccggtgc ggcaacggag
    14821 tggacgcaag tactcaacaa cgcagaactg gtgtcccttg taggtcaatc tggtgagcaa
    14881 attcagaacc aactcaccaa gattagccag ctatcccaac agatcgaaac acagctgaac
    14941 atctatcgga atctgctgca gaacacggcc gccctgccat cgcacatgtg ggggcaggtc
    15001 gagaacgatc tcaatcggct ccgtagcatc gtcgaccaag ggcagagcat agccttctcg
    15061 atgggcaatg ctgacgatgt gctgcagcag cggtttgcaa gctatgccga cctaagaaca
    15121 aacctgccgg ccaatgagac gttctccgcg acctatcaaa cctggtcgga caccaaccgc
    15181 gacacgatcg ccagcacgtt aaaggcggca agtctcacgg ccgatcagtt cgagagcgag
    15241 gaaagcgcaa tgtcctccct tcggtcaatg tccgaaacgg cggatggcca gatgaaggcg
    15301 ctgcagatcg gacaccagat cgccgctcag caggtggcgc agatgcagaa gcttcgcggt
    15361 ctcgtctcac aacagatgac gctaatggga acctggctac agaccgagca gaccgataag
    15421 gatctggctc aggcgaggcg ggaaaagttc ttcagagccg aggtgaagag tattccggag
    15481 gggcagaaga tggagccccg ctggtgagcc gcgccgtcct tgttgccttg ttgttggctg
    15541 tcgccgtagc atcgtcggca gcgacagtgc tgataatcaa ccccagagac acgctcaaat
    15601 cttccctcac tgagcagcaa cgcagtgctc gggagagatt cttcggcacc ggaaaggagc
    15661 tgccgccgat caaagatggt caggagatgc gtccgagatg gtgaaggtaa ctcgtccgtt
    15721 cctgattgcc ggacttttat gcatagccta ttcagcaccc gctttcgcac aagagggaca
    15781 cgtcctcacg gaactggaaa accaagtctc gtccgctgcg aaggggtggg agaccaccat
    15841 tatgaatgcc gcacgatccc tattttggat tctggcggca atcgagattg gtatagcggc
    15901 cgtctggctc gccactcagg ccgcgtcgct ggacagctgg ttcgccgagc tggtgcggcg
    15961 tattatgttc gtcggcttct tcgcatttat tctggagcaa ggtccaactt ttgcgagagc
    16021 cgtcgtcgac agtcttttcc agattggtgc ggacagcgat tcagcttcac ctgctgaagt
    16081 attcgacgcc ggtatccgcg tagcctcgca aatgtcgcaa caggtacagt ttggcgtctt
    16141 tgaggataat gccttggcga tcgcggcggt attggcgatg ggcgtcgtcg tcatttgctt
    16201 ctcgcttgtc gcagccattt tcgtgtcggt catggtcgag atgtatgttg gcctcctcgc
    16261 cggtatgatc atgctcggac tgggcggctc gtccttcacc aaggactttg ctgttcggta
    16321 cctgatctat gctttcggcg tcggcatgaa gctcatggcc ctggtgatga tcgccaagat
    16381 aggatcgagc gtcctgcttg gcctcgcgca agcccccacc gcatcatccg ataaattcgt
    16441 aactgcctta gcgatcgccg gtatttccgt cgtggtcttc atcatcgcaa tgtatgtgcc
    16501 gaccattctt cagggtgtcg tccagggcgc gtccgtcagc ggaggaatgg aagcgatccg
    16561 ccatggcgga caggcggcat cgttcgccgc cggtgcgggc ttcctcgccg ccggtgcggc
    16621 cggcgctggc tttgaagcgg gaaagttcgc acgagcagcg ggttcatccg tcgcaggtgc
    16681 ggctcttcga agtgtgggtg ccggaatcgg gtcggcagga cgcgctgtgg ggtccgctgc
    16741 caaggaaaag gcaatcggcg ctcccggtgc ctatgccgga tccattctcg gactagccaa
    16801 cgcaaagctc gacgagcaac gcagtgggct tagcgaatcc ctcccgagcg caacgaaatc
    16861 ccgtaatcag gaagcgaagg aagatggcag taaaccgcac gcctgaaaat ccctatcttg
    16921 ccgctcgcca ggaatggacc gagcgatatg gctcctatgt gaaggccgca gccgcatggc
    16981 gcgttgtcgg catactcagt cttgccttgg ccctcgtagg tttcagctac gctttgtacc
    17041 tcagcaccca ggtcaggctg gtgccctata tcgtggaagt cgataggctt ggaacttcgg
    17101 ttgcgtctgg cttccccgag cagatcgaat atgccgacgc ccgcgtagta cgcgccactc
    17161 taggcaactt cgtcacgagc tttcgcagcg tcaccccgga tgccgtggtg cagaagcaat
    17221 acatcgaccg cacctatgcg cttctacgca cctccgatcc gtccactcaa aaaatcaacg
    17281 attggttccg aagcaactcc ccgttcgaga aggccagatc ttcaacagtt gccatcgagg
    17341 tcaacaatat tgtggccctc tcgaaccaga cctatcagat cgactggacg gaatacgagc
    17401 gggaccggaa gggcaaggaa accgggacgc gccgctttcg gggcattgca acggtcgcgc
    17461 ttaccgcacc gcaggatgag gcgacgatcc gtcttaatcc gatcggcctc tatgtcacag
    17521 atttcgactg gacggcgcag ctataaggca ggggacttct caatgcaaaa aactcgattg
    17581 ctcacggtcg ccggctgcct agccggactc gtctttgtca gtggcgcgca ggcacaaaat
    17641 atgacaacca acgaggtgaa gggaacgaag atttcgagca agtggcgtgg cacgccaggg
    17701 ctggtcacga aaggaccgga cggaaaagtg attttcctgt tcggggaaac ccagccttct
    17761 gtggtttgct cgcccctaca ggtctgcgac atagagctcc aaggtgggga gatcgttcgc
    17821 gatgttctcg tcggtgacac ggtgcgctgg aaggtggagc ctgcgacttc gggagcaaca
    17881 gggggacagg cgattcatct ggtcgtcaaa ccttcggagc ccaaccttct cacctcgatg
    17941 gtggtcacga cctcccggcg aacctatcac atccagctca agtcccatcc cagccagtac
    18001 atggcgcgca ttggcttcga atatcccgaa gacgtatcga ccaagctctc ggacatcaat
    18061 gctcgcctcg aggccggcgg cattccaggt gccgcgcccg acaagctaga cttttcctat
    18121 tcaatcagcg gccaagcgtc atggaagccg aagcgggtct attcggatgg ggtgaagaca
    18181 tacatccatt ttccaaggtc gattttcggt caggacgcgc cggtcctctt cgtcgtttcc
    18241 ggcggtcaaa atcgcattgt caactataga atgaagaacg acatgatgat cgtggactat
    18301 gcagtcgaca aggcgatcct cgtttccggg gtcggttgga ggcagcagaa gatcatcatt
    18361 cggcggggaa gctgaacgat gcagaatctt ctttcgactg tgattgccgc cgcgcttttg
    18421 tctggttgtc aaacggcgga tcagggcttg cgtcccagct cagatgcggg agcagtcacc
    18481 ggaccggccg cgagcgccat cgccggcgac atggtgagcc gtcttgccga gcaaatcggc
    18541 cctgccacag ctacgacaac aatcagaatg gacaaggata cctccgagtt cgcgatagcc
    18601 ctcgaagcag ccttaaaggg gtggggctac acggtcgtca ccgacaagaa attggtcagg
    18661 ggcatcaagc ccgtcgagct tgcatatgca gccgagagct tcgacggaca gattctggct
    18721 cgactctcga cgccttccat tgcgttcggg cgagcttaca cgccgactgg ggccggcgcc
    18781 atgcccgcta gtccgctgtc gatcttgcag cgcaactgac ggagaatgga tatggtccag
    18841 tcgcttcagc tcggcgcgtc cagtcatgcc gacgatcaga aggccatgcg ccgcctcaac
    18901 cgcctgccga tcttcgttgc catcactgtc atcgtgcttt ttttcgccgt cgttgtgatt
    18961 ggcctgtcgt ggcgcggggt ctccctcaag cgtggcgacg acacccaaag catctccaat
    19021 actccggcga ctagcttcgg cgagcaactc aaacggggtg taacggacgg tatcatcgga
    19081 gagccagttg aacgcgaggc tttccagccg acgccagtcg ttcacaaggt cgacacgcaa
    19141 gaatccgttg ttgaaagaag gcctggggaa cgaaaggagc gacgacctaa gcttgaatcc
    19201 gaagaggagt ggaaggctcg cctgaagcga gagcaggatg agcagtatat acgcgaggcc
    19261 catcgccaac gaatggctcg cctccaagcc catgcgaccg cgctcgattc tccgctgaag
    19321 gtggacgttt ccgatatcaa gaattcaaca aatcacgcca acactcgtca gtctagaaat
    19381 ctcgaagcga agggtgcctc agacctacat gcagctgcta tgaaatcggg cctgataagc
    19441 cagcaagtcg acccgaacgg ccagatatcc aaggaggagt tttttaataa ggaaatcaag
    19501 gatcttggct acctgccgaa ccaggttgta ccgcagttgt caccttacga attgaaacgc
    19561 ggctcggtta ttccggccac attgatcact ggcctcaatt ccgatttgcc aggacgcatt
    19621 gctgctcagg tcagccagaa cgtctatgac agcgctaccg gctacagact gctcattccg
    19681 cagggagcca aactcctggg gcgctatgat tcgaagttat ccttcggcca agagcgggtt
    19741 ctggtcgtct ggaccgattt gatctttccc aacggttcaa cgctgcagat tggcggcatg
    19801 gccggcacag acgccgaagg atatggcggc ttcaaggata aggtcgaccg tcatctgtgg
    19861 cggaccttcg gttccgcggc tctagtcgca ataatcggaa ccggtatcga tatgtcgttg
    19921 ccagagagtt caacgcttgc aacgcaggac accgcctcag acgctgcaag gcgtaatttc
    19981 gcggaaagct ttggtcgggt ggcggaacag acgatctcaa agaacctcaa tgtgcagccg
    20041 acgatccgta tccgtcctgg ctacaagttc aatattctcg ttgatcaaga tattgttttt
    20101 ccgtcggttt ataatggcca ttgatggtgg cctccgcatc cggcgcatct ccctgctctg
    20161 cgaaggcccc caagaagtgc cctttccacc tagttagcga gaggttgaat gctcggaaaa
    20221 cgtgtggcaa attgtgcgcg gtaaacctca ggaagaacgg catgggtgat cacccggggc
    20281 ccgtggcccg ctggcctact agacaatcgc gccatcagtg gcgcgcaaac gatgcgacga
    20341 agggcccctt cgcaacggcg caggaacaga aggagtattc aatgcaaacg gaacttcgcc
    20401 tgttaatcga catgacagaa gctgcaaatg atgaacgaat gataaaaagt gcagtgctca
    20461 gcttcgccaa cgctcatggt tttgagcgtt ttgcgtatct gcaaacccag ggcgatgatg
    20521 ttcagacatt caactcctac ccagaggaat ggcaggacat ttacctcggc agccgctact
    20581 cgatcatcga tccggtgatc actgaagcca agcgtcgcat g
//
