LOCUS       NC_009727              48459 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Coxiella burnetii Dugway 5J108-111, complete sequence.
ACCESSION   NC_009727
VERSION     NC_009727.1
KEYWORDS    RefSeq.
SOURCE      Coxiella burnetii Dugway 5J108-111
  ORGANISM  Coxiella burnetii Dugway 5J108-111
            Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
            Coxiellaceae; Coxiella.
REFERENCE   1  (bases 1 to 2158758)
  AUTHORS   Beare,P.A., Unsworth,N., Andoh,M., Voth,D.E., Omsland,A., Gilk,S.D.,
            Williams,K.P., Sobral,B.W., Kupko,J.J. 3rd, Porcella,S.F.,
            Samuel,J.E. and Heinzen,R.A.
  TITLE     Comparative genomics reveal extensive transposon-mediated genomic
            plasticity and diversity among potential effector proteins within
            the genus Coxiella
  JOURNAL   Infect Immun 77 (2), 642-656 (2009)
   PUBMED   19047403
REFERENCE   2  (bases 1 to 2158758)
  AUTHORS   Beare,P.A., Unsworth,N., Andoh,M., Voth,D.E., Omsland,A., Gilk,S.D.,
            Williams,K., Sobral,B., Kupko,J.J. III, Porcella,S.J., Samuel,J.E.
            and Heinzen,R.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-SEP-2008) Coxiella Pathogenesis Section, Laboratory of
            Intracellular Parasites, Rocky Mountain Laboratories, National
            Institute of Allergy and Infectious Diseases, 903 S. 4th Street,
            Hamilton, MT 59840, USA
  REMARK    Protein update by submitter
REFERENCE   3  (bases 1 to 2158758)
  AUTHORS   Seshadri,R., Samuel,J.E., Myers,G., Kim,M., Huot,H., Durkin,A.S.,
            Dodson,R.J., Daugherty,S.C., Li,J. and Harkins,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-JUN-2007) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000017105.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 01:44:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,344
            CDSs (total)                      :: 2,293
            Genes (coding)                    :: 2,077
            CDSs (with protein)               :: 2,077
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 216
            CDSs (without protein)            :: 216
            Pseudo Genes (ambiguous residues) :: 0 of 216
            Pseudo Genes (frameshifted)       :: 124 of 216
            Pseudo Genes (incomplete)         :: 95 of 216
            Pseudo Genes (internal stop)      :: 37 of 216
            Pseudo Genes (multiple problems)  :: 39 of 216
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:18:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1888527
            Orig. end                         :: 1936986
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000733.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA is available from Dr. James E. Samuel,
            jsamuel@medicine.tamhsc.edu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..48459
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="PKS-like"
                     /product="NRPS-like"
                     /region_number="7"
                     /rules="(t2pks2 or ksIII)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..48459
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..41236
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /kind="single"
                     /product="PKS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41236
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21236](-)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21236)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     misc_feature    complement(539..555)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.72"
                     /tool="antismash"
     misc_feature    2390..2404
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.98"
                     /tool="antismash"
     misc_feature    complement(3276..3290)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(3310..3325)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 20.83"
                     /tool="antismash"
     tRNA            complement(4365..4440)
                     /anticodon=(pos:complement(1892932..1892934),aa:Ala,
                     seq:tgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CBUD_RS09545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CBUD_1915"
                     /old_locus_tag="COXBU7E912_1915"
                     /product="tRNA-Ala"
     gene            complement(4365..4440)
                     /locus_tag="CBUD_RS09545"
                     /old_locus_tag="CBUD_1915"
                     /old_locus_tag="COXBU7E912_1915"
     tRNA            complement(4445..4521)
                     /anticodon=(pos:complement(1893012..1893014),aa:Ile,
                     seq:gat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CBUD_RS09550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CBUD_1916"
                     /old_locus_tag="COXBU7E912_1916"
                     /product="tRNA-Ile"
     gene            complement(4445..4521)
                     /locus_tag="CBUD_RS09550"
                     /old_locus_tag="CBUD_1916"
                     /old_locus_tag="COXBU7E912_1916"
     rRNA            complement(4629..6168)
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CBUD_RS09555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="CBUD_1917"
                     /old_locus_tag="COXBU7E912_1917"
                     /product="16S ribosomal RNA"
     gene            complement(4629..6168)
                     /locus_tag="CBUD_RS09555"
                     /old_locus_tag="CBUD_1917"
                     /old_locus_tag="COXBU7E912_1917"
     misc_feature    complement(4719..4737)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.28"
                     /tool="antismash"
     cand_cluster    5976..48459
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5976..48459
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[25975:28459](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      25976..28459
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     misc_feature    complement(6076..6095)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    6472..6490
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.66"
                     /tool="antismash"
     misc_feature    6514..6527
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.29"
                     /tool="antismash"
     misc_feature    complement(6517..6530)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.08"
                     /tool="antismash"
     gene            6550..6807
                     /locus_tag="CBUD_RS09560"
                     /old_locus_tag="CBUD_1913a"
     CDS             6550..6807
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002332951.1"
                     /locus_tag="CBUD_RS09560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1913a"
                     /product="hypothetical protein"
                     /protein_id="WP_011997317.1"
                     /transl_table=11
                     /translation="MIRYCSHYKWAIASRLVWPNVRQLLHGVTDFNDGGKEMKYRIKKM
                     GLLFMSLVLMTTYLLAMTPHATSWENSTTTRWSASTESAF"
     gene            complement(6844..8043)
                     /gene="tyrS"
                     /locus_tag="CBUD_RS09565"
                     /old_locus_tag="CBUD_1919"
                     /old_locus_tag="COXBU7E912_1919"
     CDS             complement(6844..8043)
                     /EC_number="6.1.1.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tyrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819227.1"
                     /locus_tag="CBUD_RS09565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1919"
                     /old_locus_tag="COXBU7E912_1919"
                     /product="tyrosine--tRNA ligase"
                     /protein_id="WP_010957422.1"
                     /transl_table=11
                     /translation="MISSQEAFEEIKRGAVEIIHEDELLSRLAEEKPLRIKLGFDPTAP
                     DIHLGHTVVLNKLRQFQTLGHEVIFLIGDFTAMIGDPTGKNITRQPLTREIVMENTKTY
                     ETQAFRILDPDKTQVTSNSTWINKLKADDLVRLAATYTVARMLERDDFNKRYLSQQPIA
                     IHEFLYPLLQGYDSVALKADVELGGTDQKFNLLVGRELQKHFGQRPQCVLTVPLLEGLD
                     GIQKMSKSLNNYIGITEPPEEMFGKVMSISDELMWRYYELLSFRPMREINRWREEVSEG
                     RNPRDIKILLAEELVTRFHSKEAATKAHQHFIDRFKRHELPTDLDEIELTAENTHLTIG
                     YILQRAGLVNTTSEGLRMIAQGAVRIDGERVEDIKLAIPRGESHLFQVGKRRFAKVKVI
                     "
     gene            8067..9425
                     /locus_tag="CBUD_RS09570"
                     /old_locus_tag="CBUD_1920"
                     /old_locus_tag="COXBU7E912_1920"
     CDS             8067..9425
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819226.2"
                     /locus_tag="CBUD_RS09570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1920"
                     /old_locus_tag="COXBU7E912_1920"
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="WP_011997318.1"
                     /transl_table=11
                     /translation="MEYFIPCFYITWYDSELELATPDKTKGTSMKGWKSTIVIFTVIPL
                     LFVALASLLYAHASPNTKQLTLNEPHSITIVKNIDNSNSDWKKIIIKKGDTLAAIFNRL
                     KINQKDLVQLAKQYKSLTALHPNQTLYFQIKPPHQLAALKYPLSSAKTLIIKRENNRFI
                     SQIDQKPITTALGYKSVTIHHSLNQDARNAGLTYRMQKELQSIFGGQINFSRDIHRGDR
                     FEFLYQVEYVNGKKYRDGDIIAAEFSHRGKTYQAVRYTYPIAHTAYYTPDGRGIEARFL
                     HAPLHYTRISSRFTYHRLDPILHKIRPHLGVDFAARFGTPVKSIGEGRVVFIGRDGGYG
                     RTVKISYGHHYLALYGHLSRFAKIKRHQWVHKGQIIGYVGESGWATGPHLHFGFFIDGK
                     AKDWLAMKLPTDQSIPRSYETRFHKEARQLLAQLHLHQDTELAANNMKMKHPS"
     gene            9429..10547
                     /locus_tag="CBUD_RS09575"
                     /old_locus_tag="CBUD_1921"
                     /old_locus_tag="COXBU7E912_1921"
     CDS             9429..10547
                     /EC_number="2.7.1.170"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819225.1"
                     /locus_tag="CBUD_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1921"
                     /old_locus_tag="COXBU7E912_1921"
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="WP_005770633.1"
                     /transl_table=11
                     /translation="MPKERYIGLISGTSMDALDTALVQFDPLKIIATHGEPIPTELKKN
                     LVALSTGTDNSIPSMGETDVALGRLFGEAVLTLLEKAKVSSDSIQAIGSHGQTIRHMPN
                     GKHPFTLQIGDPNTIAALTGITTVADFRRRDMALGGQGAPLAPAFHEFLLRDQSENRLI
                     LNIGGIANLTFLPRDPEKSTIGFDTGPGNTLLDAWCLMNLNKDYDDQGQWAASGRVQEK
                     LVAQLLAEPYFQTPPPKSTGREYFNLNWLKKNLNGEKFDPVDIQATLVELTARSVANCC
                     RNFSMDSGSLWLCGGGARNHHLVNRLKVLCKPLRVTTTEEIGIHPDWLEAVCFAWLAKQ
                     TLEKKPGNLPSVTGAKKSAILGAIYWGEKFNY"
     gene            10594..11352
                     /locus_tag="CBUD_RS09580"
                     /old_locus_tag="CBUD_1922"
                     /old_locus_tag="COXBU7E912_1922"
     CDS             10594..11352
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819224.1"
                     /locus_tag="CBUD_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1922"
                     /old_locus_tag="COXBU7E912_1922"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_005772946.1"
                     /transl_table=11
                     /translation="MITLDRITKFYRSVKSPAVDSVSFEVKDGETLVLLGSSGSGKTTL
                     MKMINRLIEPTSGTIKIEGKDVREYNLSELRRSIGYVFQQIGLFPHMTIEKNITILLKL
                     LHYPKAKRIQRAAELLEMVHLDPQKFAQRYSDELSGGQQQRVGVARALAADPKYLLMDE
                     PFGALDAMTRSALQEEMIHLNQKLGKTIVFVTHDIFEAFRIADRIAVMHKGKLEQIGTK
                     NELLNNPATEFVEQLVKQPAQQIEDLEKNR"
     gene            11349..12929
                     /locus_tag="CBUD_RS09585"
                     /old_locus_tag="CBUD_1923"
                     /old_locus_tag="COXBU7E912_1923"
     CDS             11349..12929
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819223.2"
                     /locus_tag="CBUD_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1923"
                     /old_locus_tag="COXBU7E912_1923"
                     /product="glycine betaine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_011997319.1"
                     /transl_table=11
                     /translation="MSTPTGMFLINNASLLGVKLLEHLYLSLSATLLAIIIGIPLGTVI
                     LNRHALKNTVLSVTSIFQTIPSLALLAFLIPFIGIGFKPTIVTLTLYALLPIIRNTFMG
                     LTGVPPESVEAARAMGFTRWQRLRLVELPLALPIIVAGIRTATAMTIGITTIAAFIGEG
                     GLGDFITQGLSLNDPRLILLGAIPTALLAIALDFIIAYIESALSHRQRQLMKYKKIKLT
                     FIFILLFASLYLMIDTIIPTAFKSKKNTIVIATKNFSEQYILGDIMADMIETRTHLTVR
                     KKFNLGSTAIIQNALLNGEIDLYPEYTGTAYLTVLHHANLVSAPQIFKIVKKEYQQQFN
                     LIWLNPFGFNNSQTLAVRADFAKQHRLKTLSDLAVISPRLTIAAPAEFLKRPDALPGLK
                     RVYGFRFKRVIQMQPDLIYQAIRNKDVNVIEVFTTDGRIPAYHLVPLEDDKHLYPPYYA
                     APVIREAFLKAHPEVEKALAPLAGLIDEKTMQHLNALVDIKHESPEKVVHDFLVEKGLI
                     KLSPQAGEK"
     gene            complement(12938..14125)
                     /locus_tag="CBUD_RS09590"
                     /old_locus_tag="CBUD_1924"
                     /old_locus_tag="COXBU7E912_1924"
     CDS             complement(12938..14125)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819222.1"
                     /locus_tag="CBUD_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1924"
                     /old_locus_tag="COXBU7E912_1924"
                     /product="serine protease"
                     /protein_id="WP_011997320.1"
                     /transl_table=11
                     /translation="MKWSHWPRKTASFLFIASITFPLISVGLTAQEVYQKVKDSVYTLY
                     SVDPQSGVVRARGSAIATSKTTLVTNCHIALIGDLVVKLPNLPNMQPATIFFKNEKQDL
                     CLLKIPSANFAAVKMRPSSEVNIGEEVYAVGNPQGTEKSLSKGIISNKHPVKDGAWLRT
                     DAAIYFGSSGGGLFDAQGNLIGITTKMGGNFGFAIPTEWITHALAQMPVKNIRAEKNNF
                     DNSPIIYPDAISALSFLGTYGLDKIGLYRNNKECFLLIPGTDTNGDLASAILWNPKYDT
                     TLIVFPSTASIKEALSIIYMALLDKETKNEVSYRSKSRLYIAGQPYPLYGSQVDNHKYP
                     FLVMRFSQNPRSVFLNSRAFRVVFDDPDPNIGKAIMVYHLDGVAQALSSYNANCF"
     gene            complement(14190..14930)
                     /gene="coxK1"
                     /locus_tag="CBUD_RS09595"
                     /old_locus_tag="CBUD_1925"
                     /old_locus_tag="COXBU7E912_1925"
     CDS             complement(14190..14930)
                     /codon_start=1
                     /gene="coxK1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819221.1"
                     /locus_tag="CBUD_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1925"
                     /old_locus_tag="COXBU7E912_1925"
                     /product="Dot/Icm T4SS effector protein kinase CoxK1"
                     /protein_id="WP_005772950.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-14, bitscore: 51.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMAYMRLSVADFYDLKKGKVLGRNYRVLEYLGSGWEGEVYKVEE
                     RKTGIIRAAKLFYHRKANGENPHIHYAKKLYKLRKCPIVIQYHFHDIIYLKKKKIDFLV
                     SDFVDGEVLSSYIARQKGKRLLPFEALHLLYALTQGVEQIHFQGEYHGDIHSENIMVKK
                     KGLGFEVHLIDLLHLGSPTKDKIQQDVYDLINIFYEMIGGATGYRYCNPHIKQFVLGRK
                     HNLIREQFNTAGHLRLHLENIEWD"
     gene            15067..15516
                     /locus_tag="CBUD_RS09600"
                     /old_locus_tag="CBUD_1926"
                     /old_locus_tag="COXBU7E912_1926"
     CDS             15067..15516
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012220117.1"
                     /locus_tag="CBUD_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1926"
                     /old_locus_tag="COXBU7E912_1926"
                     /product="hypothetical protein"
                     /protein_id="WP_011997321.1"
                     /transl_table=11
                     /translation="MIKRLIALSITLFLPLLGVANTDNALQRLVVTVENTTNKTLTYRN
                     IYEPAGTIKKIEVEHTVLLPGQRSRILIFGDGTGLIASVNFTDNDANELLFEFNDPAQY
                     YQGGYTDFKTTAQHLATSTTQVHNPAKPSAKLLLWTEINYQVSNA"
     gene            15634..16086
                     /locus_tag="CBUD_RS09605"
                     /old_locus_tag="CBUD_1927"
                     /old_locus_tag="COXBU7E912_1927"
     CDS             15634..16086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819219.1"
                     /locus_tag="CBUD_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1927"
                     /old_locus_tag="COXBU7E912_1927"
                     /product="hypothetical protein"
                     /protein_id="WP_011997322.1"
                     /transl_table=11
                     /translation="MLKKIHAYIVDELMFLPILIVNWSLWIVSGFHKVSRIITKQIWVA
                     PNGWIPWLHTHFHGTFLDPFVVPLFFILTFLQVLAGLLLTVALFKLEFLDYRKKDFFKA
                     GLFVGAFTIAVMSFGQNIANADEDIFQLSSYLTTTLVSYLFCSIPS"
     gene            complement(16465..17712)
                     /locus_tag="CBUD_RS13315"
                     /old_locus_tag="CBUD_1928"
                     /old_locus_tag="COXBU7E912_1928"
     CDS             complement(16465..17712)
                     /NRPS_PKS="Domain: Condensation_LCL (34-151). E-value:
                     8.7e-13. Score: 39.9. Matches aSDomain:
                     nrpspksdomains_CBUD_RS13315_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CBUD_RS13315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CBUD_1928"
                     /old_locus_tag="COXBU7E912_1928"
                     /product="hypothetical protein"
                     /protein_id="WP_011997323.1"
                     /sec_met_domain="Condensation (E-value: 9.7e-10, bitscore:
                     35.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRLLKENELNCVEKIDFLRHYLIEHNSVLALGFCIEIPDDKLIQ
                     SLKLFKEKHKIFNSTIELNDGIQLKEHPEKEIIFQNKGEIINNKQLYDLMYEEFRKAFD
                     PQKELMLRLTKATYNNLCVLIFSIDHIIVDGMSFVYFISDFIKIMTSPNVANTSKTHTL
                     NRPDVLNLSPDENRALDENIKRVLSGPPVKKFTGMEFIHIEVNATDTLTLVERCKKYQV
                     SIHNAVLTAMASALIVYYGQSQMTINFRTAFNLRSLLKTKLEDSLGDYHSEINTLLVVS
                     KSINFWEIAKYLNRDIEENISKNTPFEKLKSSISDIEKAKDLTAYKELKKLNFPTISIS
                     SRKIILPKSAEFLKFSFGIGPYNYSNNPNYFTYQAINHLFEDKLRLTFEYDAKHLTKVQ
                     INFLVHHTLNFLLKSE"
     aSDomain        complement(17260..17610)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS13315_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.70E-13"
                     /label="CBUD_RS13315_Condensation_LCL.1"
                     /locus_tag="CBUD_RS13315"
                     /protein_end="151"
                     /protein_start="34"
                     /score="39.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHIIVDG"
                     /tool="antismash"
                     /translation="CIEIPDDKLIQSLKLFKEKHKIFNSTIELNDGIQLKEHPEKEIIF
                     QNKGEIINNKQLYDLMYEEFRKAFDPQKELMLRLTKATYNNLCVLIFSIDHIIVDGMSF
                     VYFISDFIKIMTS"
     gene            complement(17712..17990)
                     /locus_tag="CBUD_RS09620"
                     /old_locus_tag="CBUD_1929"
                     /old_locus_tag="COXBU7E912_1929"
     CDS             complement(17712..17990)
                     /NRPS_PKS="Domain: PP-binding (14-80). E-value: 5e-10.
                     Score: 31.5. Matches aSDomain:
                     nrpspksdomains_CBUD_RS09620_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819214.1"
                     /locus_tag="CBUD_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1929"
                     /old_locus_tag="COXBU7E912_1929"
                     /product="acyl carrier protein"
                     /protein_id="WP_011997324.1"
                     /sec_met_domain="PP-binding (E-value: 4.6e-09, bitscore:
                     33.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKVVNTKKRAWVALTDTIQKILPDITQEQLQPQNSLRMLGANSM
                     DRAEIIISVMETLDLKLPLSYFSEEKNLGELADLLDTQLHIMERNKK"
     aSDomain        complement(17751..17948)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09620_PP-binding.1"
                     /evalue="5.00E-10"
                     /label="CBUD_RS09620_PP-binding.1"
                     /locus_tag="CBUD_RS09620"
                     /protein_end="80"
                     /protein_start="14"
                     /score="31.5"
                     /tool="antismash"
                     /translation="LTDTIQKILPDITQEQLQPQNSLRMLGANSMDRAEIIISVMETLD
                     LKLPLSYFSEEKNLGELADLL"
     gene            complement(18136..18750)
                     /locus_tag="CBUD_RS09625"
                     /old_locus_tag="CBUD_1929a"
     CDS             complement(18136..18750)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (15-178). E-value: 1.9e-36. Score:
                     117.5. Matches aSDomain: nrpspksdomains_CBUD_RS09625_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF027439.4"
                     /locus_tag="CBUD_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1929a"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_080512905.1"
                     /transl_table=11
                     /translation="MNYQTIIIEKKPLYYLVTLNRPQIKNSLDITILQELHAALDEIEK
                     DKEVHSIILQGQIGVFCTGMDFTNLQPPKSRQPSDNTLYIKLLHRFVTFPRIIISCVEG
                     AVIAGGMGLVASSDLVVATSQSQFSLSEAIWGLLPVCVTPYLIRRVGFQAAYRLGFTTE
                     TIDAKEAYRLQLIDLLSDEPLKKFTPMSCALAVLIYARLKD"
     aSDomain        complement(18217..18705)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09625_ECH.1"
                     /evalue="1.90E-36"
                     /label="CBUD_RS09625_ECH.1"
                     /locus_tag="CBUD_RS09625"
                     /protein_end="178"
                     /protein_start="15"
                     /score="117.5"
                     /tool="antismash"
                     /translation="LVTLNRPQIKNSLDITILQELHAALDEIEKDKEVHSIILQGQIGV
                     FCTGMDFTNLQPPKSRQPSDNTLYIKLLHRFVTFPRIIISCVEGAVIAGGMGLVASSDL
                     VVATSQSQFSLSEAIWGLLPVCVTPYLIRRVGFQAAYRLGFTTETIDAKEAYRLQLIDL
                     "
     gene            complement(18756..19994)
                     /locus_tag="CBUD_RS09630"
                     /old_locus_tag="CBUD_1931"
                     /old_locus_tag="COXBU7E912_1931"
     CDS             complement(18756..19994)
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006084 - acetyl-CoA metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0010142 - farnesyl diphosphate biosynthetic
                     process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020129.4"
                     /locus_tag="CBUD_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1931"
                     /old_locus_tag="COXBU7E912_1931"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_011997326.1"
                     /transl_table=11
                     /translation="MTTKIGIESINAYCGQASLDIKTLFAARDLDLTRFDNLMMQKKSV
                     NLPCEDSVTSAVNAAKPILDPLSQSERNQIALLITATETGLDFGKSLSTYIYPYLNLSK
                     NCRLFEIKQACYGGTAALQMAAAWVSSQPSSQVKALIIATDAARAAARKTYAEPSQGTG
                     AVAMLISKNPEILILDNGATGYYGYEIMDTCRPEPDLETGNPDLSLLSYLDCLDNCYRI
                     YCEKVEDINIQTTFNYFAFHTPFAGMVKGAHRQLLRKNGYTDAQFIEADFQKRVAPSLV
                     YCEQVGNIYSATVYLALCGIIDNTDFINPKRVGIFSYGSGCCAEFYSGILQPIAKEKLG
                     ILSIKQSLENRYLLDMLAYEKIIDINQEWFFGVKNKNVDITPFEEIYTRQFANKGLLIL
                     DKIENYKRYYRWS"
     gene            complement(20001..21236)
                     /locus_tag="CBUD_RS09635"
                     /old_locus_tag="CBUD_1932"
                     /old_locus_tag="COXBU7E912_1932"
     CDS             complement(20001..21236)
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (76-409). E-value:
                     7.8e-40. Score: 129.0. Matches aSDomain:
                     nrpspksdomains_CBUD_RS09635_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: t2pks2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF005490.0"
                     /locus_tag="CBUD_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1932"
                     /old_locus_tag="COXBU7E912_1932"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_011997327.1"
                     /sec_met_domain="t2pks2 (E-value: 9.4e-149, bitscore:
                     492.8, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.4e-25, bitscore:
                     85.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMFPVYITGLGVQTSIGLSTKTFSAALRAGNCSIKRVSNYPELE
                     FPVLMAQLEGFNETLIASSLPGVSRLPYELQVTLAAAVEAWKDAGFMDHPPLSNRVGLV
                     VTGDNLLPNLNFKYYKAFTNNPTYLSPKAITQCFDSYHLGVISEVLNITGAGFVAGGAS
                     ASGNIALIQAQQLLQQESLDACLVVGNFTHFSPIAIQAFYNSGALGGAHFIDHPNKASR
                     PFDKNRDGFILGEAAGAILLEKEKPTQRRSTVYGKILSGSMALSATQSTAPDITAEVRV
                     MRQTLSQTQLSPKDITYLNTHGTSSLLGDVTEMAAIRTIFAEHLPKVWLNSTKSLIGHS
                     LNSAGILEAIATIIQLKNNFLHPNINLDEPIDLQANWVGKKLVENIHNHYALSNSFGFF
                     GIHTCLLLEKEE"
     aSDomain        complement(20010..21008)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09635_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="7.80E-40"
                     /label="CBUD_RS09635_PKS_KS.1"
                     /locus_tag="CBUD_RS09635"
                     /protein_end="409"
                     /protein_start="76"
                     /score="129.0"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="VTLAAAVEAWKDAGFMDHPPLSNRVGLVVTGDNLLPNLNFKYYKA
                     FTNNPTYLSPKAITQCFDSYHLGVISEVLNITGAGFVAGGASASGNIALIQAQQLLQQE
                     SLDACLVVGNFTHFSPIAIQAFYNSGALGGAHFIDHPNKASRPFDKNRDGFILGEAAGA
                     ILLEKEKPTQRRSTVYGKILSGSMALSATQSTAPDITAEVRVMRQTLSQTQLSPKDITY
                     LNTHGTSSLLGDVTEMAAIRTIFAEHLPKVWLNSTKSLIGHSLNSAGILEAIATIIQLK
                     NNFLHPNINLDEPIDLQANWVGKKLVENIHNHYALSNSFGFFGIHTCLLLEK"
     gene            21309..23084
                     /locus_tag="CBUD_RS09640"
                     /old_locus_tag="CBUD_1932a"
     CDS             21309..23084
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (34-494). E-value:
                     8.4e-173. Score: 567.1. Matches aSDomain:
                     nrpspksdomains_CBUD_RS09640_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012337.4"
                     /locus_tag="CBUD_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1932a"
                     /product="polyketide synthase"
                     /protein_id="WP_011997328.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.9e-81, bitscore:
                     269.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 3.1e-171, bitscore:
                     567.1, seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGWRIDMRLFNAKLFYRLKNLLFHSNHSISADPIAIIGMAGRYP
                     DVKNLEDFWQKLKIGWDGITEIPASRWDWHEYYLPGSAGKNLPNKSCSKWGGFLTDVDK
                     FDALFFNISPKEAKKISPEERLMLEVVWALLENSGYTPEKLKKQTNGSVGVFVGSTWND
                     YRLLCGILGKSAEYGLASIGLIPNRISYFFDLHGPSVGVDTLCSSSLTVLHLACESLRR
                     GECRYAIVGGVNLILHPSKYLLLNAAGFLSPSGHCKSFSADGDGFVPAEGIGAVMLKPL
                     KQAQADGDNILAIIRGTAVNHGGKANRYTVLKLFSGIRKNKADKNNKAAEKTRHTGPQA
                     GPTVPNPVSQAEVIQQALKNANLTPEQINYIEAHGTGTELGDPVEMAGLCKAFEKRIAT
                     TKCPIGAVKSNVGHMEAASGIVSLIKVILQSQHKQLVPSIHAKKLNPLIDFTHTPFYIQ
                     QELSDWSPTKDELRRAGISSFGVGGSNGHVIIEQAPEKEISSPPEKPYYLLTFSAKLQE
                     SLQQRMNDFHNYLVQQSSLVSLANIAYTLNATRVHFPENRAAIIVSSTEEIIHTLNKIK
                     SNEKPENYLLQVIKK"
     aSDomain        21411..22790
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09640_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.40E-173"
                     /label="CBUD_RS09640_PKS_KS.1"
                     /locus_tag="CBUD_RS09640"
                     /protein_end="494"
                     /protein_start="34"
                     /score="567.1"
                     /tool="antismash"
                     /translation="IAIIGMAGRYPDVKNLEDFWQKLKIGWDGITEIPASRWDWHEYYL
                     PGSAGKNLPNKSCSKWGGFLTDVDKFDALFFNISPKEAKKISPEERLMLEVVWALLENS
                     GYTPEKLKKQTNGSVGVFVGSTWNDYRLLCGILGKSAEYGLASIGLIPNRISYFFDLHG
                     PSVGVDTLCSSSLTVLHLACESLRRGECRYAIVGGVNLILHPSKYLLLNAAGFLSPSGH
                     CKSFSADGDGFVPAEGIGAVMLKPLKQAQADGDNILAIIRGTAVNHGGKANRYTVLKLF
                     SGIRKNKADKNNKAAEKTRHTGPQAGPTVPNPVSQAEVIQQALKNANLTPEQINYIEAH
                     GTGTELGDPVEMAGLCKAFEKRIATTKCPIGAVKSNVGHMEAASGIVSLIKVILQSQHK
                     QLVPSIHAKKLNPLIDFTHTPFYIQQELSDWSPTKDELRRAGISSFGVGGSNGHVIIEQ
                     AP"
     CDS_motif       21897..21941
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS09640_0001"
                     /evalue="8.20E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="CBUD_RS09640"
                     /protein_end="211"
                     /protein_start="196"
                     /score="15.0"
                     /tool="antismash"
                     /translation="GPSVGVDTLCSSSLT"
     CDS_motif       22416..22463
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS09640_0002"
                     /evalue="4.10E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="CBUD_RS09640"
                     /protein_end="385"
                     /protein_start="369"
                     /score="15.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTELGDPVE"
     CDS_motif       22521..22565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS09640_0003"
                     /evalue="4.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="CBUD_RS09640"
                     /protein_end="419"
                     /protein_start="404"
                     /score="12.6"
                     /tool="antismash"
                     /translation="GAVKSNVGHMEAASG"
     gene            23081..24526
                     /locus_tag="CBUD_RS09645"
                     /old_locus_tag="CBUD_1932b"
     CDS             23081..24526
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ACP_beta (134-200). E-value: 1.7e-19.
                     Score: 61.4. Matches aSDomain:
                     nrpspksdomains_CBUD_RS09645_ACP_beta.1"
                     /NRPS_PKS="Domain: Thioesterase (245-476). E-value:
                     1.1e-29. Score: 96.4. Matches aSDomain:
                     nrpspksdomains_CBUD_RS09645_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="CBUD_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1932b"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_011997329.1"
                     /sec_met_domain="PP-binding (E-value: 2.7e-15, bitscore:
                     53.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.7e-25, bitscore:
                     86.9, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTTANEVLKTLIEKLKTKSLTPTTYYELLNAIGDLYVQGHDID
                     WDAFYQSESHQLIMLLNYSFLKKTHWCDTNKIQSSPPQPLPGEKIQLSELEVKPPQIEN
                     APSVPDKPEILSPKMKEDNLRQNTNEPVNEAIRKIIAETLFIDSNLIHDTEFFQDLGID
                     SILGVEIAQKIQKKFNIELNAATLYTYSTVSQLANFIVQQANIPSTSDEQKEVMQIQAQ
                     DQALSISISPWFRTTLLSRPDIDLFCFHCAGGGPALFNGWRVLLPKNIGLHLIELPGRE
                     KRIGEPLETNAQKLVENIGNEIIGAKLKRYIFFSHSLGALLAFYVAKYLQQKKVNLPEI
                     IFLSSCPSPENDIGLLKDFKKNSLSDQTLLEKLDELGVNGIPSEIRYNSDALKIYLNIL
                     RADMDLEFNTPWFEQLLATDRLSSTFVIMAGENDRFISLKEMESWKEYTSGSFFKKSFP
                     GNHFYLTVDKAAVCDFIANMIVT"
     aSDomain        23483..23680
                     /aSDomain="ACP_beta"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09645_ACP_beta.1"
                     /evalue="1.70E-19"
                     /label="CBUD_RS09645_ACP_beta.1"
                     /locus_tag="CBUD_RS09645"
                     /protein_end="200"
                     /protein_start="134"
                     /score="61.4"
                     /tool="antismash"
                     /translation="AIRKIIAETLFIDSNLIHDTEFFQDLGIDSILGVEIAQKIQKKFN
                     IELNAATLYTYSTVSQLANFI"
     aSModule        23483..24508
                     /domains="nrpspksdomains_CBUD_RS09645_ACP_beta.1"
                     /domains="nrpspksdomains_CBUD_RS09645_Thioesterase.1"
                     /final_module
                     /incomplete
                     /locus_tags="CBUD_RS09645"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        23816..24508
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS09645_Thioesterase.1"
                     /evalue="1.10E-29"
                     /label="CBUD_RS09645_Thioesterase.1"
                     /locus_tag="CBUD_RS09645"
                     /protein_end="476"
                     /protein_start="245"
                     /score="96.4"
                     /tool="antismash"
                     /translation="LFCFHCAGGGPALFNGWRVLLPKNIGLHLIELPGREKRIGEPLET
                     NAQKLVENIGNEIIGAKLKRYIFFSHSLGALLAFYVAKYLQQKKVNLPEIIFLSSCPSP
                     ENDIGLLKDFKKNSLSDQTLLEKLDELGVNGIPSEIRYNSDALKIYLNILRADMDLEFN
                     TPWFEQLLATDRLSSTFVIMAGENDRFISLKEMESWKEYTSGSFFKKSFPGNHFYLTVD
                     KAAVCDFIA"
     gene            complement(<24660..24764)
                     /locus_tag="CBUD_RS13320"
                     /pseudo=""
     CDS             complement(<24660..24764)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819213.1"
                     /locus_tag="CBUD_RS13320"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLVSNDIYLNRFYNNKHHINDKNTVDSLADSASQT"
     gene            24743..>25849
                     /locus_tag="CBUD_RS13325"
                     /pseudo=""
     CDS             24743..>25849
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (2-247). E-value:
                     1.1e-41. Score: 134.8. Matches aSDomain:
                     nrpspksdomains_CBUD_RS13325_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="CBUD_RS13325"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 6.1e-32, bitscore:
                     107.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRLKQALQATVNTNYNLRSNFDEQAGTLQQIIHDHVQAVLEEHT
                     VEKQIESKAIVQKTITQPFDLAKDALFRFALINSKYNQTVTLLVVFHHIILDSTQYGKL
                     MQCISNNYHHAPDLNITDKDEINHLEDYIAWEEEKIKNADVQYWVSKLKKYPLNNNLPY
                     QTIEIKRTQLKQVSKLYELDNSLYSKLSSFSKKSGHSVFNIIKTIWAMLISLYCNQDKV
                     VIAYPFNTRPKQFKDIKGSFVNTLFFPFERKGNFIDQLDMQKKEINLSYIKNKYISTVD
                     LVAQLGRHNAAFNVAVSQTDPRFYGPTLNESCTYFKTTSIGAAELFLLYKENEECLRYS
                     LQTLDKLFDDDFLDRVAQHFKNLLRKVLD"
     aSDomain        24749..25483
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS13325_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.10E-41"
                     /label="CBUD_RS13325_Condensation_LCL.1"
                     /locus_tag="CBUD_RS13325"
                     /protein_end="247"
                     /protein_start="2"
                     /score="134.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIILDS"
                     /tool="antismash"
                     /translation="RLKQALQATVNTNYNLRSNFDEQAGTLQQIIHDHVQAVLEEHTVE
                     KQIESKAIVQKTITQPFDLAKDALFRFALINSKYNQTVTLLVVFHHIILDSTQYGKLMQ
                     CISNNYHHAPDLNITDKDEINHLEDYIAWEEEKIKNADVQYWVSKLKKYPLNNNLPYQT
                     IEIKRTQLKQVSKLYELDNSLYSKLSSFSKKSGHSVFNIIKTIWAMLISLYCNQDKVVI
                     AYPFNTRPKQFKDIKGSFVNTLF"
     aSModule        24749..27718
                     /complete
                     /domains="nrpspksdomains_CBUD_RS13325_Condensation_LCL.1"
                     /domains="nrpspksdomains_CBUD_RS13330_AMP-binding.1"
                     /domains="nrpspksdomains_CBUD_RS13330_PCP.1"
                     /locus_tags="CBUD_RS13325"
                     /locus_tags="CBUD_RS13330"
                     /monomer_pairings="Val -> Val"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     gene            25976..28459
                     /locus_tag="CBUD_RS13330"
     CDS             25976..28459
                     /NRPS_PKS="Domain: AMP-binding (1-408). E-value: 9.1e-99.
                     Score: 322.7. Matches aSDomain:
                     nrpspksdomains_CBUD_RS13330_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (512-581). E-value: 3.1e-17. Score:
                     54.5. Matches aSDomain: nrpspksdomains_CBUD_RS13330_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="CBUD_RS13330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_237699815.1"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-106, bitscore:
                     352.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.9e-08, bitscore:
                     31.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2e-14, bitscore:
                     51.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADKIPAAIAVEYENQRLTYRELNSKANQVAHHIHYYYQKIIQQ
                     PFLADTLIGISADRSLEMIIGILGILKAGGAYTPIDPGYPKNRVEYILENTQIKLVLTK
                     KSLLKKFRNNIYLLALDSEECLSADDDNLAINTTADHLAYVIYTSGTTGDPKGVMIEHK
                     SVISLVKENGFLNIQANDVLLQLASPIFDAAIFEIWGALLNGAKLILPKGKLDILNSID
                     QFKKFLTKNKISILWLTKTLFDNLYQLDNTLFNSIRYLLIGGESLAPSLIQKLCSQKLR
                     PQYILNAYGPTEGTTFSTIYFCDNRLYGSVPIGKPFNARKAYILDKSLNPVAIGVIGEM
                     YIGGAGLARGYLNQPELTAKCFIANPFATAADQAKGYTRLYKTGDLVRYLPDGNIEYMG
                     RSDFQVKINGYRIELGEIETVLNRYPAVKQVVVLVKEHEGNKYLVAYYVAENEFNATDL
                     KNYLSKNLPDYMLPHAYVYLKQFPLTINGKLDRAALPEPALVNADQYVAPRNELEEKMV
                     SILEELLKVRPIGIKDDFFRIGGNSILALKFVAKLKSQINLSLKISELFSSRDIESITA
                     LVNNRKSYQPIVSMNKDRNQKNTLFMIHSGFSGCEVYNNLVTELDNDYHCYGIDNYNLY
                     HDKKIDSLHKIAALYLGYIKLCQKNGNSYRLLGWSSGGTIALEIAAILEKEGVKDITVY
                     LLDTILSDATIRRLSPKVDSSYLKELESKMKGFGYEDSYIKKVLSVCIPESLISHDVIS
                     KMLNDTNVILFKALKEDAKRDQWGLEKLTKYALSLKDNNVGNYCRKLTVINVNLSHKQM
                     PLGQYLKFMKNTGEH"
     aSDomain        25979..27199
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS13330_AMP-binding.1"
                     /evalue="9.10E-99"
                     /label="CBUD_RS13330_AMP-binding.1"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="408"
                     /protein_start="1"
                     /score="322.7"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="QADKIPAAIAVEYENQRLTYRELNSKANQVAHHIHYYYQKIIQQP
                     FLADTLIGISADRSLEMIIGILGILKAGGAYTPIDPGYPKNRVEYILENTQIKLVLTKK
                     SLLKKFRNNIYLLALDSEECLSADDDNLAINTTADHLAYVIYTSGTTGDPKGVMIEHKS
                     VISLVKENGFLNIQANDVLLQLASPIFDAAIFEIWGALLNGAKLILPKGKLDILNSIDQ
                     FKKFLTKNKISILWLTKTLFDNLYQLDNTLFNSIRYLLIGGESLAPSLIQKLCSQKLRP
                     QYILNAYGPTEGTTFSTIYFCDNRLYGSVPIGKPFNARKAYILDKSLNPVAIGVIGEMY
                     IGGAGLARGYLNQPELTAKCFIANPFATAADQAKGYTRLYKTGDLVRYLPDGNIEYMGR
                     SDFQVKIN"
     CDS_motif       26177..26218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS13330_0001"
                     /evalue="3.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="81"
                     /protein_start="67"
                     /score="17.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYTPID"
     CDS_motif       26402..26461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS13330_0002"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="162"
                     /protein_start="142"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGDPKGVMIEH"
     CDS_motif       26975..27061
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS13330_0003"
                     /evalue="6.00E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="362"
                     /protein_start="333"
                     /score="53.7"
                     /tool="antismash"
                     /translation="IGVIGEMYIGGAGLARGYLNQPELTAKCF"
     CDS_motif       27164..27229
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS13330_0004"
                     /evalue="4.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="418"
                     /protein_start="396"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YMGRSDFQVKINGYRIELGEIE"
     aSDomain        27512..27718
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBUD_RS13330_PCP.1"
                     /evalue="3.10E-17"
                     /label="CBUD_RS13330_PCP.1"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="581"
                     /protein_start="512"
                     /score="54.5"
                     /tool="antismash"
                     /translation="EEKMVSILEELLKVRPIGIKDDFFRIGGNSILALKFVAKLKSQIN
                     LSLKISELFSSRDIESITALVNNR"
     CDS_motif       27965..28024
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBUD_RS13330_0005"
                     /evalue="3.10E-09"
                     /label="NRPS-te1"
                     /locus_tag="CBUD_RS13330"
                     /protein_end="683"
                     /protein_start="663"
                     /score="29.3"
                     /tool="antismash"
                     /translation="YRLLGWSSGGTIALEIAAIL"
     gene            complement(28834..29844)
                     /locus_tag="CBUD_RS09655"
                     /old_locus_tag="CBUD_1935"
                     /old_locus_tag="COXBU7E912_1935"
     CDS             complement(28834..29844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012570444.1"
                     /locus_tag="CBUD_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1935"
                     /old_locus_tag="COXBU7E912_1935"
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="WP_011997331.1"
                     /transl_table=11
                     /translation="MPDSLSSRVVNACSLGNIEEVNKTFSSPSLEQKNQIIKFDHYACF
                     HVAAANGHFDVIDFIFNYVKSITDKIPADEAVISVFLDRNGEGFKAALANQHIKIVERI
                     LEEEYLFQYCIDIIAENPTFMKIIWNSSLRNCILYIFEECCSQDISSVQRILELVPKPS
                     QHLLLDDPGKLPVSISFYRVNLSHFKRACQSGKLDIVQLLWSLSSSSNQKKLIENRFEA
                     SFILAAKNGHVEILKQLVKWVESKQLKISLLKSKDFSAFIYAADKGYLEIVQLIWESIP
                     SPLQLEALKASNFAAYRLATKNQHHSVRSFLETKSDEVNRRKMKNAVNQGVFPKK"
     gene            complement(30093..30644)
                     /locus_tag="CBUD_RS09660"
                     /old_locus_tag="CBUD_1936"
                     /old_locus_tag="COXBU7E912_1936"
     CDS             complement(30093..30644)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997332.1"
                     /locus_tag="CBUD_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1936"
                     /old_locus_tag="COXBU7E912_1936"
                     /product="hypothetical protein"
                     /protein_id="WP_011997332.1"
                     /transl_table=11
                     /translation="MRRKSACEKFTETLVRSLAVFSIFSNPETMASAKVTPLPNLNPVG
                     CETALREGKDNFVTVITGFEGCPYYDKLLFTFGQACEELKRDCFSFIYTSEENPQKYNP
                     ALNTKTVLGCLGYIPVASPLLSQHLRVTAPDPLGKQMLGPLNLGGGLNGYSTVEEVKSF
                     INELPGNWTGEDFKHLRLSR"
     gene            complement(31124..32080)
                     /locus_tag="CBUD_RS09665"
                     /old_locus_tag="CBUD_1937"
                     /old_locus_tag="COXBU7E912_1937"
     CDS             complement(31124..32080)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997333.1"
                     /locus_tag="CBUD_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1937"
                     /old_locus_tag="COXBU7E912_1937"
                     /product="aldo/keto reductase"
                     /protein_id="WP_011997333.1"
                     /transl_table=11
                     /translation="MKYATLSSGQRFPLLGLGTWKSPENELYTAIRKAIEIGYRHIDCA
                     PIYFNEPTIGKALKDAIKAGDVRREELWITSKLWNSDHAPEDVEPACKKTLNDLQLDYL
                     DLYLIHWPVAQKHSVGYNIPENADAFIPLSKLPITSTWKSMENLVGQGLTKSIGVSNFS
                     ISRMEELLNQASFKPTVNQVESHPFLAQNELLNFCRKNNIVMTAYSPLGSTDRPETRKA
                     KDEPSLLENPVINAIAEAHNATPAEILIAWQLHRDVAVIPKSVNPARLQQNFESLDIAL
                     TAEDLEAIKALNSGCRLIDGSIFTIKGSPYTLESLWK"
     gene            32349..33524
                     /locus_tag="CBUD_RS09670"
                     /old_locus_tag="CBUD_1940"
                     /old_locus_tag="COXBU7E912_1940"
     CDS             32349..33524
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005769541.1"
                     /locus_tag="CBUD_RS09670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1940"
                     /old_locus_tag="COXBU7E912_1940"
                     /product="hypothetical protein"
                     /protein_id="WP_011997334.1"
                     /transl_table=11
                     /translation="MLSIEVEEKPPLLNEHSNRDACPYFNLGRLLRDINRLLPTLPYVF
                     KTIHSIMGVSRYYGIKPIMLLYDLIEIVNSDEKSDCGRVNINELLAMAFFSAEKEYIAI
                     LELCLSALITVQEKRFFSSLYLIAASATNADVLSCLDVMEIPIPTDPAARRAFLRALYE
                     NRTISHSIYTKYYCKVQHYCKLFAVDAREITPDDILKNRIFQLYQDEDIEKLLDDFQRY
                     FHQKRFDKIMNVLHAVENPSLINRIMLHLLGLTNIEVSAKQFLLTSLSFRIDSWFSFLE
                     AITFISDDERQYLLLRNFMQSIQTNAGLINFLLIQAEYESSMIPEQKHSIKDSLLYRIL
                     AILCSVKSDFLLVDQRQKRFLLNAIDLIAMDADLSTAIRIKKNTRLCGTGT"
     gene            33563..34153
                     /locus_tag="CBUD_RS09675"
                     /old_locus_tag="CBUD_1941"
                     /old_locus_tag="COXBU7E912_1941"
     CDS             33563..34153
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819211.1"
                     /locus_tag="CBUD_RS09675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1941"
                     /old_locus_tag="COXBU7E912_1941"
                     /product="hypothetical protein"
                     /protein_id="WP_080512906.1"
                     /transl_table=11
                     /translation="MTYLYQPYDFNSDYCSGPLKAEFITMFSPHLIPDYKTYRYRRLIQ
                     ILYNVINGRIGIDKDTYSRTSHKCGLVWRMEEAVTLLFIAGVTIGPFTSFFCAAILGYI
                     ATIFVDRLTYSRLDYVITHYSFRYPFLREDINRVIPDLAGNEDIAIFKKNFYQLPINKV
                     IDRLEQKFFEITRERKIHEDRDEKFVSLGFASV"
     gene            34622..35590
                     /gene="cas1f"
                     /locus_tag="CBUD_RS09680"
                     /old_locus_tag="CBUD_1942"
                     /old_locus_tag="COXBU7E912_1942"
     CDS             34622..35590
                     /GO_function="GO:0004520 - DNA endonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="cas1f"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997337.1"
                     /locus_tag="CBUD_RS09680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1942"
                     /old_locus_tag="COXBU7E912_1942"
                     /product="type I-F CRISPR-associated endonuclease Cas1f"
                     /protein_id="WP_011997337.1"
                     /transl_table=11
                     /translation="MTMEQFSSSELKTILHSKRANLYYLEHCRVMQKDGRVLYLTEAKK
                     SNLYFNIPIASTTVILLGTGTSITQAAIRMLAQAGVLVGFCGGGGTPLYMGNDIEWMTP
                     QSEYRPTEYLQGWMKFWFDDKKRLRAAKTLQHARMAYLEAVWKKDRELKVSGFDFPDSA
                     IMRAIEASKAQIDRSSTVSILLNNEAQLTKILYKFAATQNSIDTFTRNRDSTDKANGFL
                     NHGNYLAYGLAATTLWVLGIPHGFAVMHGKTRRGALVFDVADLIKDAIVLPWAFICAKE
                     NATEQEFRQQCLQSFAEHKSLDFMFNQVKKIALDHDEGSAP"
     misc_feature    35604..35618
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     gene            35644..36891
                     /locus_tag="CBUD_RS13335"
                     /old_locus_tag="CBUD_1942a"
     CDS             35644..36891
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037707.4"
                     /locus_tag="CBUD_RS13335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1942a"
                     /product="HD domain-containing protein"
                     /protein_id="WP_237699770.1"
                     /transl_table=11
                     /translation="MLDAFANRIGDNTWQTVITQEGLVTVKKILRQTASKNTAVSCHWI
                     RSRSRSDLVWVVGNRQKFNREGVVPVNRTTRNLMYAHTENDWTYLPLIKALVAIAALLH
                     DWGKASQLFQEKLNPKNKVGFKGDPIRHEWVSCLLLNALIQIHQDNSDQMDDRGWIEAL
                     ISGDIDEAKIKALTIKQKIKPLADLPPIAKFVAWLIVSHHRLPLNKDADMRAEYCPEID
                     DVLNRITQRWGYENNYDELDYQQRVEQCFNFPNGLLSNSKSWMKQIQKWSQRLLTCEGQ
                     ALQSLSDGSYRSVLSYARLCLMLGDHYYSSQGADEKWKNISGLFANTDFKTKALKQKLD
                     EHLVGVAKHGLNTAHLLPAFESEPPIAQDIVALKKPCLKEFRWQDKAVEKIKLWRKDNT
                     KKQGFFCREYGEHGLR"
     gene            36869..38941
                     /gene="cas3f"
                     /locus_tag="CBUD_RS13340"
                     /old_locus_tag="CBUD_1942b"
     CDS             36869..38941
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="cas3f"
                     /inference="COORDINATES: protein motif:HMM:TIGR02562.1"
                     /locus_tag="CBUD_RS13340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1942b"
                     /product="type I-F CRISPR-associated helicase Cas3f"
                     /protein_id="WP_237699816.1"
                     /transl_table=11
                     /translation="MASTGCGKTFANAKVMQALSADGNSLRFILALGLRTLTLQTGDEY
                     RKRVGLDDTELAVLIGSRAVMELHQKAKLEADEQSFEESGSESQEALLDEEVDYDSAIP
                     EEGFATVLREQRDKKFLYAPVLVCTIDHLMAATETKRGGRYILPTLRLMSSDVVIDEID
                     DFSGKDLVAIGRLVHLAGMLGRKVMISSATIPPDLAEGCFKAYRDGWQIYCNTHNASPT
                     IGCAWIDEFNTDVSSNVGVEVQDAILAYREQHAKFIEKRVAKLLKQGVKRKADIALCDG
                     IFSDFAENHNDEDVVVNKQQAYFKCIVDSAIAKHQHHHTVDNQSKLAVSFGVVRMANIQ
                     PCIALANYLLSVEMPADTQIRTMPYHSQQVLLMRHKQEQHLDEVLKRKEDEGEQPQAFS
                     NPVIRQHLDHIYQAEPQVKNVMFVLVATPVEEVGRDHDFDWAVVEPSSYRSIIQLAGRV
                     RRHRKTEVQFPNISLLQYNWRGVRDSHREKAIVFKWPGFEDSKHRLESHDLKKLLDANA
                     ILQRVDAIPRIQKPKDLQPKKKLADLEHSVIKSLLANYRSDSNGPANLQGYLREAWFLT
                     AYPQQLVPFRQGQSNLKVFLTFDEDKQVYMFCEKNEKGFPVPRELPLGISRVQLDDNAS
                     KRLWLKRNFEKEIEALSEKQEVSMRNASMRYGELSFPYYEKNKYEYNDQFGLVRV"
     gene            38952..40208
                     /gene="csy1"
                     /locus_tag="CBUD_RS09690"
                     /old_locus_tag="CBUD_1944"
                     /old_locus_tag="COXBU7E912_1944"
     CDS             38952..40208
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="csy1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005769537.1"
                     /locus_tag="CBUD_RS09690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1944"
                     /old_locus_tag="COXBU7E912_1944"
                     /product="type I-F CRISPR-associated protein Csy1"
                     /protein_id="WP_043880971.1"
                     /transl_table=11
                     /translation="MLNSSIDEFFKKRKVAWLKKAINASMDEIEVSEKELECEQVFALE
                     HWLPSAAKRAGQISISTHPCTFSHPSSRKNKNGYASSIIANSKRSEDGYLRSGNVTVKA
                     DALGNAAALDVYKFLSLEMADGQTLLSHIQQDSDLAQQLLNIKSESYNTLKDGFLAMIN
                     RNSDCVTSSKIKQVYFPLDNGYHQLSILSASGIMFELRKRIDTIRFSDEAKAARVCEKN
                     NEIYDGDYKQIVNITTIGYGGTKPQNISVLNNQNGGKVHLISSEPPKLIKRDAHFPTVD
                     FFSQSLRYFQCKDLFYSLHELFLNHKNDWNIRHERDEYYQAIIDLIIEKMWLVRSVSQV
                     QYNPDSTRLNETQKIWLCEVNKENRETENDWLDDLCQAIARFIFTGYEKLLGKKAFIFS
                     DDEFKHIHKQVVKNKEALR"
     misc_feature    38975..38988
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 26.06"
                     /tool="antismash"
     gene            40205..41167
                     /gene="csy2"
                     /locus_tag="CBUD_RS09695"
                     /old_locus_tag="CBUD_1945"
                     /old_locus_tag="COXBU7E912_1945"
     CDS             40205..41167
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="csy2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017253164.1"
                     /locus_tag="CBUD_RS09695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1945"
                     /old_locus_tag="COXBU7E912_1945"
                     /product="type I-F CRISPR-associated protein Csy2"
                     /protein_id="WP_011997339.1"
                     /transl_table=11
                     /translation="MSYNKILLIPHLRIHNANALSSPFTIGFPAMTAWLGATHALQRNL
                     NERGIPVTIPATGVVSHQMDLQTYRGNDDYVSSIINTGNPLVPKTKREKGEPWHNFERP
                     PFIEEARCHLDVSLLIEFRGVSQEQDDEIKEQVSHLLNCKMKVAGGDIQSFNPPAILLI
                     EDGNDADLRRLSRKIMPGYVLIERRDLMIEAMQQGQDALDALIDYVAIHHSCEKTEDGD
                     VLWESHRKTQIDKPPGWIVPIATGFHGISELGQAKNQRDPETPHRFAESLVTLGEFKMP
                     HRFESVTDMLWCYQVDSTNNLYQCVALNTITENLYDEFG"
     gene            41190..42260
                     /gene="csy3"
                     /locus_tag="CBUD_RS09700"
                     /old_locus_tag="CBUD_1946"
                     /old_locus_tag="COXBU7E912_1946"
     CDS             41190..42260
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="csy3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012220114.1"
                     /locus_tag="CBUD_RS09700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1946"
                     /old_locus_tag="COXBU7E912_1946"
                     /product="type I-F CRISPR-associated protein Csy3"
                     /protein_id="WP_193330528.1"
                     /transl_table=11
                     /translation="MAKKENIDIASVLSFEKKLIPSDGYMFGTSWDKKSEVTPLKLREK
                     AVRGTISNRFNKNDSKTFLDDPMKLDADVERPNLQRVDACALDQNQDTLKLCFTLKVLG
                     GITNPSACNNALFKQSYKAAAKIYIDTHGFTELATRYAENLANARFLWRNRFGAERIEV
                     RVNASNKTVSQKWAFDATKFNLHTFDSSDTSVKELGALIANALSSEDDYLLLDVNCYVQ
                     VGSSQEVYPSEELVLDKSSSDKKGKKTKILYAVNDIAAMHSQKIGNAIRTIDTWYPDFT
                     NQEQTAGPIAIEPYGAVTNLGRAYRTPKDKQDFYTFFDAWARGEQLARIEDEHYVMAVL
                     VRGGVFGKSDKKESDK"
     gene            42269..42826
                     /gene="cas6f"
                     /locus_tag="CBUD_RS09705"
                     /old_locus_tag="CBUD_1947"
                     /old_locus_tag="COXBU7E912_1947"
     CDS             42269..42826
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /gene="cas6f"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819208.1"
                     /locus_tag="CBUD_RS09705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1947"
                     /old_locus_tag="COXBU7E912_1947"
                     /product="type I-F CRISPR-associated endoribonuclease
                     Cas6/Csy4"
                     /protein_id="WP_011997341.1"
                     /transl_table=11
                     /translation="MNYYFDINLLSDAEIPSTVLINAVCKKLHKLLCDLDSTRIGISFP
                     KYKITLGNVLRLHGTEFDLQKLHEVSWLGGMNGYCKISEVATVPVNTKHRTVYRKQPTM
                     SQSKLKRLLKRGTITNDEVKSYKAKMVAEKGLNNPYLDLVSGTNCQRHRRYIVLGELLD
                     EPVEGGFDQFGLSKTVTVPWFD"
     gene            42823..42924
                     /locus_tag="CBUD_RS09710"
                     /old_locus_tag="CBUD_1947a"
     CDS             42823..42924
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819207.1"
                     /locus_tag="CBUD_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1947a"
                     /product="hypothetical protein"
                     /protein_id="WP_010957411.1"
                     /transl_table=11
                     /translation="MKENCIGDTKILNEFCGEKEGSIFFLSPIILAL"
     gene            43067..43228
                     /locus_tag="CBUD_RS09715"
                     /old_locus_tag="CBUD_1948"
                     /old_locus_tag="COXBU7E912_1948"
     CDS             43067..43228
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002332950.1"
                     /locus_tag="CBUD_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1948"
                     /old_locus_tag="COXBU7E912_1948"
                     /product="hypothetical protein"
                     /protein_id="WP_011997342.1"
                     /transl_table=11
                     /translation="MLAEALQELQQLGGWSSFSMVLRYAHLSSHRLREAAKRIYVTKSL
                     HAESVKYF"
     tRNA            complement(43273..43345)
                     /anticodon=(pos:complement(1931837..1931839),aa:Thr,
                     seq:cgt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CBUD_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CBUD_1949"
                     /old_locus_tag="COXBU7E912_1949"
                     /product="tRNA-Thr"
     gene            complement(43273..43345)
                     /locus_tag="CBUD_RS09720"
                     /old_locus_tag="CBUD_1949"
                     /old_locus_tag="COXBU7E912_1949"
     gene            43476..43898
                     /locus_tag="CBUD_RS09725"
                     /old_locus_tag="CBUD_1950"
                     /old_locus_tag="COXBU7E912_1950"
     CDS             43476..43898
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819206.1"
                     /locus_tag="CBUD_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1950"
                     /old_locus_tag="COXBU7E912_1950"
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="WP_005769527.1"
                     /transl_table=11
                     /translation="MQRNRTAGFTLMELLIVIAIIGILIIIAIPSYHTYTRRAHFTEVV
                     QATAPYKLGVKECYQMTNDLSECSAGDNGVPPAIASGSGTGLVDAIEIQNGVITVTPQV
                     KYGIEAKDNYILTPTPEREGLTWASSGGGVAAGYAN"
     gene            43888..45441
                     /locus_tag="CBUD_RS09730"
                     /old_locus_tag="CBUD_1951"
                     /old_locus_tag="COXBU7E912_1951"
     CDS             43888..45441
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819205.1"
                     /locus_tag="CBUD_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1951"
                     /old_locus_tag="COXBU7E912_1951"
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_011997343.1"
                     /transl_table=11
                     /translation="MQTKVEGLAHILLQTNALTNSQIARAIEQAAGAQSPLLHYLVTEK
                     IVSSEKIAEACATYFGLEAINLQTQPLNPSLCHEIPRKYLMRYAFIPLAVKSPTLAISD
                     PLYFPLIEELQFQTNKQYKIVFAPYKSFAALINNFVSRQIYETVSQGKASIVELVNQVL
                     TDAIYREASDVHFEPMQQHYRIRMRIDGILHTTTLLPNTQSPAMSSRLKVLAELDISEK
                     RLPQDGRFYFTTLTHLKRDCRLSSCPTLFGEKIVIRLLNPVHHLLKFEELGLEEKPKQL
                     IMKKIKQPQGLILVTGPTRSGKTVSLYAALNQINSTQKNISTVEDPIEIQLAGVTQVNI
                     RPKAGLNFAAVLRAFLRQDPDVIMVGEIRDFETASIAVRAAHTGHLVLSTLHTNSAVEC
                     ITRLIDMGIEPFNLASVLKLVVAQRLVRQLCAHCQATKISCPFCLNGYQGRTGIYEVLP
                     ITPSIIELILQKRSAQEINACAIQEGMQTLWQAALNKAKTGITNLNEIYRVIQSENNYA
                     "
     gene            45434..46489
                     /locus_tag="CBUD_RS09735"
                     /old_locus_tag="CBUD_1952"
                     /old_locus_tag="COXBU7E912_1952"
     CDS             45434..46489
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819204.1"
                     /locus_tag="CBUD_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1952"
                     /old_locus_tag="COXBU7E912_1952"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_011997344.1"
                     /transl_table=11
                     /translation="MLKYWKNRIRSKNILGLFRQLNVLINAEIPLAQALALLAGGSHSG
                     SLRQLILAIWSKIENGLSLSETLKIYPRYFHTVHHEIIHAGEQSGKLGELLKLLIHYEE
                     GLFIFKKKIQKAIRYPLTVLSIALGVTIGLLEFVIPQFQNAFSEFGSQLPFFTQVIINL
                     AHNVRAYGLLIFFSFSLFLFVFVYAKKHSDKFSKSVDHALIKIPLIGKGIQNTMITLWI
                     KVLATLSAAGIPLNKALITANHIIRNHALRQALDKLPCWISEGVSFSTAIERCGFFSHQ
                     AIQLIHIGENSGTLNEMLNKVAVIYQEEIDERYDRLSECLEPAIMIVLALLIGGLIIAM
                     YLPVFRIGSAL"
     gene            46515..47375
                     /locus_tag="CBUD_RS09740"
                     /old_locus_tag="CBUD_1953"
                     /old_locus_tag="COXBU7E912_1953"
     CDS             46515..47375
                     /EC_number="3.4.23.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819203.1"
                     /locus_tag="CBUD_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CBUD_1953"
                     /old_locus_tag="COXBU7E912_1953"
                     /product="A24 family peptidase"
                     /protein_id="WP_011997345.1"
                     /transl_table=11
                     /translation="MQIISFLQFHFYITIVAIAVIGLIVGSFLNVVIVRYPTLLAARWR
                     RECQEYLNLPVEPKPKFNLATPRSQCPRCKKTLKILHNLPLISYLTLRGRCAYCHEKIS
                     PLYPIVELLCAILSVAIVIRYQISWQALAGLLLTWVLIVLFFIDLKTQLLPDAITLPTL
                     WFGLSLSLFYMFVSPYQAIFGAILGYGLLWITAAFYQLIRKKEGMGRGDFKMVSMLGAW
                     FGPGIVLNVLLLAVFLGLITSFMLLALKKISVKQPIPFGPFIAVAGWISLLSGPVLIHK
                     LISYL"
     gene            47386..47985
                     /gene="coaE"
                     /locus_tag="CBUD_RS09745"
                     /old_locus_tag="CBUD_1954"
                     /old_locus_tag="COXBU7E912_1954"
     CDS             47386..47985
                     /EC_number="2.7.1.24"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_819202.1"
                     /locus_tag="CBUD_RS09745"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CBUD_1954"
                     /old_locus_tag="COXBU7E912_1954"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_011997346.1"
                     /transl_table=11
                     /translation="MLRIGLTGGIGSGKSTVANYFAELGAPVIDADQIAHEITKPDQAA
                     FKQIINHFGSAVLTKGKFLNRTKLRELIFENPDDRQWLENLLHPLIIAKMKTQLKKIKA
                     PYCILAIPLLAEASQSVDFIDRILVVDAPETLQIQRTKSRDQLSDQQIQLILQSQSPRE
                     KRLAIADDVIVNDQTIPILRKAVFQLHCKYLQIAQT"
ORIGIN
        1 tagctacccg gcaatgccac tggcgtgaca accggaacac cagaggtacg tccactccgg
       61 tcctctcgta ctaggagcag ctcctctcaa atctccaacg cccacggcag atagggaccg
      121 aactgtctca cgacgttcta aacccagctc acgtaccact ttaaatggcg aacagccata
      181 cccttgggac cggctacagc cccaggatgt gatgagccga catcgaggtg ccaaacacca
      241 ccgtcgatat gaactcttgg gtggtatcag cctgttatcc ccggagtacc ttttatccgt
      301 tgagcgatgg cccttccata aaggaccacc ggatcactaa gacctacttt cgtacctgct
      361 cgacttgtca gtctcgcagt caagcaccct tatgcctttg cacacaatgc acgatttccg
      421 accgtgctga gggtaccttt gtactcctcc gttactcttt tggaggagac cgccccagtc
      481 aaactaccca ccatacactg ttcccgaccc ggattacggg acagggttag aacctcaaac
      541 acgccagggt ggtatttcaa ggttggctcc actggagcta gcgctccagc ttcaaagcct
      601 cccacctatc ctacacaggc atattcaaag ttcagtgtaa agctgtagta aaggttcacg
      661 gggtctttcc gtctagccgc gggtacgctg catcttcaca gcgatttcaa tttcactgag
      721 tcttgggtgg agacagcgtg gctatcgtta cgccattcgt gcaggtcgga acttcactct
      781 ttcctatgtt tccataggga gtagactata ccattttctc accaagcaac cttaggagat
      841 catttatttc atgcctacgt ttacctgatg gattcatcag ataagccatt tttattattt
      901 caattaaatg ttgtttattt aaatgaaaat tggtatgtat ttttttacag atttcagaaa
      961 aatatcgaaa atctttttgt ttacctcctc taagaggata gttatcgaag tgtggaatta
     1021 ttcgcttcac aagatctttt acggaacgga cttcatattt atacgtacga tcccctcgtg
     1081 aaaatctaat tgctccacat tcaaaaaacg aatgtatctc ttttaagaga ggtaaatctc
     1141 tttgatttaa cgtgatggaa aaagatggtc ttgtttcaat accaattttt aacttttttc
     1201 tgaagttaaa tgatatcgaa aaacaccctt ctccttctgt taaaccactt acataccatg
     1261 gctctaaatg taaatacata aataaattct ccatagtcac ttacttcttg agtataaacc
     1321 caagggcaag aagtcagcgt attgcacaca aatgcgtgcc tcacctttcg gatcagtcgt
     1381 tacggggtca tttaagactt ccctcgggat tgccctttgc taaaaagcag gagggttccc
     1441 ccgatatgag ctgactttat cactaaactt tacagtttag cggggcaatt ttttacccga
     1501 caaggaattt cgctacctta ggaccgttta ttgacgttat gttaatcatg ggataatgat
     1561 taacaggttt cttttgaaaa ccctctatat cgctatagag atcggactct atcatcacac
     1621 ttagaatgga ttttttctaa gtacgctcgg cgtattagtc tctgaggatt ctaatcaaaa
     1681 agattagtct ttcctgctga ttgtccgcac ctcgcagatt tttactacct caattttagt
     1741 tgagatgagt actggaggat actcggagtt tccagcatat agccaagttt atttacgtaa
     1801 ctacaacggt taatttatag ttacggccgc cgtttaccgg ggcttcgatc aagagcttcg
     1861 cccgagggct aaccccatca cttaaccttc cggcaccggg caggcgtcac accctatacg
     1921 tcctcttacg agtttgcaga gtgctgtgtt tttagtaaac agtcgcagcc acctggtatc
     1981 tgcaaccctt ttcagctcca gtcgcaagga ccttcactta ccaagggcgc accttctccc
     2041 gaagttacgg tgccattttg cctagttcct tcacccaagt tctctcaagc gccttggtat
     2101 tctctacctg tccacctgtg tcggtttata gtacggtttt acaatacctg aagcttaggg
     2161 acttttcctg gaagcgtggc atcaatcact ttgcacgaac aagttcgtac ttcgtcatca
     2221 tgtctcggaa ttgagttccc ggatttgcca aagaaccctt cctacacact taaaccacca
     2281 caaccatcgg gtggctgacc tagccttctc cgtcctccca tcgcagtatt gtaaagtacg
     2341 ggaatattaa cccgtttccc atcgactacg catttctgcc tcgccttagg ggccgactca
     2401 ccctgcgccg attaacgttg cgcaggaaac cttagacttt cggcgtgtgg gtttttcacc
     2461 cacattatcg ttacttatgt cagcattcgc acttctgata cctccagcaa acctctcgat
     2521 tcaccttcac aggcttacag aacgctcctc tacccatcag aagacagatg gcagaagact
     2581 gaggacagaa agataaaaat taactccagc ttttgtgcaa accctttagc attttcgcaa
     2641 tatcctgata gttattgcgg aagtctaccc aggttttttc attcaaataa cctaaatcaa
     2701 aacaatatcg taaccacaca cgcatctcat ctgccgaacc cattgcaatt aaaataaatc
     2761 gcttagattc agccgtagaa acactctgct ttccaaaccc ttcagcaata ttcgcgcaaa
     2821 ttgatttact tgcttgacgg atttggcttg ccaatccata ttgctcttct ttaggcatac
     2881 ttaaagttag tttatgaagc tttaaagaaa gcttatacgc tttctgaaaa accactaaat
     2941 cttcaaagct agatatttct tttttcatat ttctgtcatc tgtcatctgt catctgtctt
     3001 ctgatgccgc agcttcggta cacagtttga gccccgttaa atcttccgcg caggacgact
     3061 cgaccagtga gctattacgc tttctttaaa ggatggctgc ttctaagcca acctcctggc
     3121 tgtctgagcc ttcccacatc gttttccact taactgtgat tttgggacct tagctggcga
     3181 tctgggctgt ttccctttcc accacggacc ttatcacccg cagtgtgtct cccgtgctaa
     3241 aacttcttgg tattcggagt ttgcctcggt ttggtaggcc gggatggccc cctagccgaa
     3301 acagtgctct acccccaaga gtcatacacg aggcgctacc taaatagctt tcgaggagaa
     3361 ccagctatct ccgagcttga ttagcctttc actcctatcc acagctcatc ccctaatttt
     3421 tcaacattag tgggttcggg cctccagtca gtgttacctg accttcaccc tggccataga
     3481 tagatcgttc ggtttcgggt ctactcgttg caactaaacg cccatttcgg actcggtttc
     3541 cctacgcctc ccctagacgg ttaagctcgc tacaacaagt aagtcgctga cccattatac
     3601 aaaaggtacg cagtcacact tccgaagaaa tgctcctact gcttgtacgc atacggtttc
     3661 aggttctatt tcactcccct cgccggggtt cttttcacct ttccctcacg gtactggttc
     3721 gctatcggtc agtaaggagt atttagcctt ggaggatggt ccccccatgt tcagtcaaga
     3781 taccacgtgt cccgacctac tcatcgttac ccacattatt tactctttcg cgtacggggc
     3841 tatcacccgc tatggctgaa ctttccagaa cattctgcta gaacaaataa tgatttagta
     3901 actgggctgt tccgctttcg ctcgccgcta ctgacggaat ctcggttgat ttcttttcct
     3961 ctgggtactt agatgtttca gttccccagg ttcgcctcgt atacctatga attcagtata
     4021 cgataacctc gaaaggttgg gtttccccat tcggaaatct ccggatcatc gcttgtttgc
     4081 cagctccccg aagcttatcg caggctacta cgtccttcat cgcctcttac tgccaaggca
     4141 tccaccatat gcgcttattc acttgaccat gcaaccctaa atgattccag ggttgttatg
     4201 tcaataacga catagaatac ctaaatggcg cctttacttt acatttcacc aaattgttaa
     4261 agagcagcgt gcaagtttca cgcatcaaca aacctgtgtc aaggaattaa cacaggtttg
     4321 ttgacgccag aaatcaagtt ttggaagcgg ttaattttaa agtttggtgg agccaggcgg
     4381 agtcgaaccg ccgaccctct gcttgcaagg cagatgctct cccaactgag ctatggcccc
     4441 gagatggtgg gtctgggaag atttgaactt ccaacctcac ccttatcagg ggtgcgctct
     4501 aaccaactga gctacagacc cgagttcatg gataattgaa tcggatctga atactcagat
     4561 cctggatcct ttaaaaatta agaaagcagt ttgtgtggat accggtacaa gtattggatc
     4621 actaaaagta aggaggtgat ccagccgcag gttcccctac ggctaccttg ttacgacttc
     4681 accccagtca tggatcatac cgtggtgagc ggcctcccga aggttagcct acccgcttct
     4741 ggtacaattc actcccatgg tgtgacgggc ggtgtgtaca aggcccgaga acgtattcac
     4801 cgcgacatgc tgattcgcga ttactagcga ttccaacttc atggagtcga gttgcagact
     4861 ccaatccgga ctacgagcag ttttctggga ttagctccac ctcgcggctt ggcaaccctt
     4921 tgtactgccc attgtagcac gtgtgtagcc ctacccgtaa gggccatgat gacttgacat
     4981 catccccacc ttcctccggt ttatcaccgg cagtctcctt agagttcccg acttgactcg
     5041 ctggcaacta aggacgaggg ttgcgctcgt tacgggactt aacccaacat ctcacgacac
     5101 gagctgacga cagccatgca gcacctgtca ctcggttccc gaaggcacca aatcatctct
     5161 gacaagttcc gaggatgtca agggtaggta aggtttttcg cgttgcatcg aattaaacca
     5221 catgctccac cgcttgtgcg ggcccccgtc aatttctttg agttttaacc ttgcggccgt
     5281 actccccagg cggagaactt aacgcgttag cttcgctact aagaagtgaa cttcccaaca
     5341 gctagttctc atcgttgacg gcgtggacta ccagggtctc taatcctgtt tgctccccac
     5401 gctttcgcgc ctcagtgtca gtattggtcc aggaagtcgc cttcgccact ggtgttcttt
     5461 ccgatatcta cgcatttcac cgctacaccg gaaattccac ttccctctac catactcaag
     5521 atacccagta tcgggtgcaa ttcccaggtt aagcccaggg ctttcacatc cgacttaaat
     5581 atccacctac gcgcgcttta cgcccagtga ttccgattaa cgcttgcact ctctgtatta
     5641 ccgcggctgc tggcacagag ttagccagtg cttcttctgt gggtaacgtc aacgcccaag
     5701 gatattaccc ttgagaattt cttccccacc gaaagtgctt tacaacccga aggccttctt
     5761 cacacacgcg gcattgctgg atcagggttt cccccattgt ccaatattcc ccactgctgc
     5821 ctcccgtagg agtctgggcc gtgtctcagt cccagtgtgg ctgatcgtcc tctcagacca
     5881 gctacggatc gtcgccttgg taggccatta ccccaccaac aagctaatcc gacgtaggct
     5941 catcttatag cacgaggtcc gaagatcccc cgctttgctc caaagagatt atgcggtatt
     6001 agcccgagtt tccccaggtt atcccccact acaaggtaga ttcctacgca ttactcaccc
     6061 gtccgccact cgccgccagg gagcaagctc cccgcgctgc cgttcgactt gcatgtgtta
     6121 agcatgccgc tagcgttcaa tctgagccag aatcaaactc ttcaattaaa tataacgtta
     6181 tgcctttaca aaaaaggcac aaaaaaggct cgacacaaaa cactgcagtt agcaggctgt
     6241 gtgtcgaaaa tcttggtgat tcaacgactt gcacagtacc cacacaaact gcttccgttt
     6301 gctgctaaat ttttaaagag caattccatt aaggaaagga tggctatttt acgcgtcccg
     6361 taagcaatgt caacaagtat cgcgtgcttt tccttaaccc cgcttgggag caagaactcc
     6421 atagctgggt tggaaatagt accctagtgt acgctggatg acaatagatt ccttgggaaa
     6481 cgttctcaaa ttcaattata gcatactagc cctatttttc attaaaaaat caatcaatta
     6541 gcattatttt tgatcagata ttgctcacat tacaagtggg cgatcgccag cagattagtt
     6601 tggccaaatg ttagacaatt gcttcatggc gttacagatt tcaatgacgg aggtaaagag
     6661 atgaagtata gaatcaaaaa aatgggtctg cttttcatga gcttggtatt gatgacaaca
     6721 taccttttgg cgatgactcc tcatgcaacc tcatgggaga attctaccac cacccgatgg
     6781 agcgctagca ccgaaagcgc cttctaatga agttaaccac ccgggcagca ggtccgggtt
     6841 gtgttaaatg accttcactt tcgcaaaccg ccgctttccc acttgaaaaa gatggctttc
     6901 acctcgaggg atagctaatt taatatcttc aacacgttca ccatcgatgc gcacagctcc
     6961 ctgtgcaatc attcgtaagc cttccgaggt ggtattcacc aatccggcgc gttgcaaaat
     7021 gtagcctatc gttaaatggg tattttcagc cgttaattca atttcatcaa gatcggtcgg
     7081 taattcatga cgtttaaacc ggtcaataaa atgttgatgc gcttttgttg cggcttcttt
     7141 actgtgaaag cgcgtcacta attcctcggc taataggatt tttatatcac gcggatttct
     7201 tccttccgac acttcttcac gccatcggtt aatttctcgc atcggtcgaa aactcaataa
     7261 ttcataataa cgccacatca attcatccga tattgacatc actttcccaa acatttcctc
     7321 gggtggttcg gtgatgccga tgtagttatt taatgatttc gacatttttt gaatcccatc
     7381 tagcccttcc aataaaggca cggttaatac gcattgcggt ctttgcccaa agtgtttttg
     7441 caattcacgc ccgactaata aattaaattt ttgatccgtg ccacctaatt caacatccgc
     7501 cttcaacgcc accgaatcgt agccttgtaa taaggggtac aaaaattcat gaatggcaat
     7561 cggttgctgc gacagataac gtttattaaa atcatcgcgt tccaacatgc gcgccaccgt
     7621 ataagtggca gctaaccgca ctaaatcatc ggcttttaat ttatttatcc aggtagagtt
     7681 agaagtaact tgcgttttat caggatctaa aatccgaaag gcttgcgttt cataagtttt
     7741 ggtattctcc atcacgattt cacgcgtgag tggttggcgc gtgatatttt ttcctgtcgg
     7801 gtcaccgatc atcgcagtga aatcaccgat taaaaaaatc acctcgtgcc ctaacgtttg
     7861 aaattggcgc aatttattca gtaccaccgt atggcccaaa tgaatatcgg gagcggttgg
     7921 atcaaatcct aatttaattc gaagcggctt ttcttccgcc aatcgggaaa gcaattcatc
     7981 ctcatgaata atttcaacag cccctctttt aatttcttcg aaagcttctt gtgacgaaat
     8041 cattacgtta aattcctaat cataatttgg agtattttat tccgtgcttt tatattacgt
     8101 ggtatgattc agaattggaa ctggcaaccc cggacaaaac aaagggaacc tcaatgaaag
     8161 gttggaaatc aacaatcgta atttttactg tcatccccct acttttcgtc gcactcgcaa
     8221 gtttacttta cgctcatgcc tccccgaaca cgaaacaact aacgctcaat gaacctcatt
     8281 caatcactat tgtaaaaaat atagacaact ctaattcgga ttggaaaaaa ataattatta
     8341 aaaaggggga tactttagcg gctattttta atcgtctaaa gattaaccaa aaagatttag
     8401 ttcaactggc aaaacaatat aaatcgttga ccgctcttca tcccaatcaa acactctatt
     8461 ttcaaatcaa accgccccac caattggccg cgctcaaata tcccctctca tccgccaaga
     8521 ctttgatcat taaacgcgag aacaatcgct tcatcagcca aatagaccaa aaaccgatta
     8581 ccaccgcatt gggttacaaa tccgtaacca tacatcattc tctgaatcaa gatgccagaa
     8641 acgccggttt gacctatcgg atgcaaaaag aacttcaatc gatttttggc gggcagatta
     8701 atttttcacg cgatattcac cgcggggatc gttttgaatt tttgtatcaa gttgaatacg
     8761 tcaacgggaa aaagtatcgc gacggcgata tcatcgccgc ggaattcagc catcggggca
     8821 aaacctatca agctgttcgc tacacttatc cgatcgcgca tacggcctat tacacgccgg
     8881 acggtcgtgg gattgaagcg cgtttcttac atgcgccatt gcattacact cgcatcagca
     8941 gtcgttttac ctatcatcgt ttagacccta ttttacataa aatacgccct cacttgggag
     9001 tcgattttgc cgcacgtttc ggaacgcccg ttaagtccat cggcgaaggg cgtgtcgttt
     9061 ttatcggacg agatggcggc tatggaagga ccgttaaaat tagttatggg catcattatc
     9121 tggcgctgta tgggcatctg tcgcgttttg cgaaaattaa acgccaccag tgggtgcaca
     9181 aagggcaaat catcggatac gtgggtgaat ccggctgggc aaccggtcct caccttcatt
     9241 ttggattttt catcgatggt aaagccaaag attggttagc catgaaactg cctaccgacc
     9301 aatccattcc ccgcagttat gaaacccgtt ttcacaaaga agctagacag ttgttagctc
     9361 aattgcatct ccatcaagac actgaattag cggcgaataa catgaaaatg aaacatccga
     9421 gttaaccggt gccaaaagaa cggtatatcg gtcttatttc cggcacgagc atggatgcgc
     9481 ttgataccgc tctcgttcaa ttcgatccat tgaaaatcat tgcaacgcat ggggaaccta
     9541 tcccgacgga attgaaaaaa aatcttgtgg ctttatccac cggcactgat aattccatcc
     9601 ccagcatggg agaaaccgac gttgccttgg gacggctttt tggcgaagct gtcttaacgc
     9661 tgttagaaaa agcgaaggtt tcctcggatt ccattcaggc cattggcagt cacgggcaga
     9721 caattcgaca catgcccaac gggaaacatc cttttactct ccaaatcggc gaccctaaca
     9781 ccattgccgc cctcaccggc attacgacag tggccgattt tcgacgtcgc gatatggctt
     9841 taggggggca aggagcgccg ttagcgcctg cttttcatga atttctttta cgcgatcaaa
     9901 gcgaaaaccg gttgattttg aatattggcg gtattgccaa tctcaccttt cttccgcgcg
     9961 accctgaaaa atctaccatt ggttttgaca cggggccagg aaacactttg ttggacgcct
    10021 ggtgcttaat gaatttaaat aaagattacg atgatcaagg acagtgggcc gcgagtggac
    10081 gtgtgcaaga aaaattagta gcgcaattgt tggcagaacc ttattttcaa accccgcccc
    10141 ccaaaagcac cggtcgcgaa tattttaacc ttaattggct taaaaaaaat ttgaatggcg
    10201 aaaaatttga tcccgtcgat attcaggcaa cgctcgttga attaacggca agaagcgttg
    10261 ccaattgctg tcgaaatttt tctatggatt cgggaagtct gtggttatgc ggcggcgggg
    10321 cccgcaatca tcatttggtt aatcgtttaa aagtattgtg caaaccactg cgtgttacca
    10381 caacagaaga aattgggatt catcccgatt ggcttgaagc cgtttgtttc gcttggcttg
    10441 ccaaacaaac cttagaaaaa aaacccggca atttacccag cgtcactggc gctaaaaaat
    10501 ccgctatttt aggcgcgatt tattggggtg aaaaatttaa ttattaaaat ttagagtctg
    10561 tttacgattc gctctatccg ttataatagc atcatgatca cgctcgaccg cattacgaaa
    10621 ttctaccgct cggtcaaatc ccccgctgtc gattcggttt cctttgaagt caaagatggt
    10681 gaaacccttg tcttgctggg ttcttcagga agcggtaaga ccactctcat gaaaatgatc
    10741 aatcgactta tcgaacccac ctcgggaaca attaaaattg aaggaaaaga tgttagggaa
    10801 tacaacctga gcgaactgcg tcgctccatc ggctatgtgt ttcagcaaat cggattattc
    10861 cctcatatga caattgaaaa aaatatcact atcttgttaa aactgctgca ttatccgaaa
    10921 gctaagcgca tccaacgtgc tgctgaattg ctcgaaatgg tgcatttaga tcctcaaaag
    10981 tttgcacagc gttattccga tgaactctcg ggtggccaac aacagcgtgt cggtgtggct
    11041 cgcgctttgg cagccgatcc caaatattta ttgatggatg aacccttcgg cgcgttagac
    11101 gcaatgacac gttctgcttt acaagaggaa atgattcatc ttaaccaaaa gttaggtaaa
    11161 acaatcgttt ttgtcactca cgatatcttt gaagctttcc gtatcgccga tcgcatcgcg
    11221 gtgatgcaca aaggcaagct tgaacaaata ggtacaaaaa atgaattact caataatccc
    11281 gctaccgaat tcgtagaaca attagttaaa cagcctgcgc agcaaattga agatttggaa
    11341 aaaaatcgat gagcaccccc acaggaatgt ttttgataaa taacgcctcc ttactcggag
    11401 taaaattatt agaacatctt tatctttcct tatcagccac ccttttagcc attattatcg
    11461 gaattccatt gggcactgta attttaaacc gacatgccct gaaaaacacg gttttaagcg
    11521 ttacaagcat tttccaaact attcctagcc ttgctttact cgccttttta attcccttta
    11581 ttggcatcgg attcaaaccc accattgtca ctttaacgct ttatgcgtta ttacccatta
    11641 ttcgtaacac ctttatggga ttgactggtg ttcctcctga aagcgtcgag gcagcacgag
    11701 caatgggatt cactcgctgg caacgcttgc gtttagttga actacccctg gccttaccca
    11761 ttattgtcgc cggcatccga acagcaacgg ccatgaccat tggcattacc acaatcgctg
    11821 catttattgg cgagggtggt ttaggcgatt ttatcactca aggcctgtct ttaaacgatc
    11881 cgcgattaat tttactcgga gcaatcccga ccgctctatt ggctatcgct ttagatttca
    11941 ttatcgctta tattgaaagt gcgttgtcgc accgccaacg gcagttaatg aaatataaaa
    12001 aaattaaatt aacgtttatt tttattctct tatttgcttc tctttactta atgattgata
    12061 caatcatccc aactgctttt aaatcgaaaa aaaatacgat cgttattgcc actaaaaatt
    12121 tttctgaaca atatatcctt ggcgatatca tggccgacat gattgaaacc cgaactcact
    12181 taactgtgag aaagaaattt aatctcggat caaccgccat cattcaaaat gctttattaa
    12241 acggggaaat tgatctctat cctgaataca ccggaacggc ttacttaacc gttttacatc
    12301 atgctaacct tgttagcgct cctcagatct ttaaaatagt taaaaaggaa taccagcagc
    12361 aattcaattt aatttggtta aatccgtttg gttttaataa ctcacaaact ttagcggtta
    12421 gggccgattt tgcaaaacag catcgtctta aaaccctgag cgatctcgct gtcatttcac
    12481 cccgcctcac tattgctgcg ccggcagaat ttctaaaacg ccccgacgcg ctcccgggcc
    12541 ttaaaagggt ttatgggttt cgttttaaac gcgttattca aatgcaaccg gatttaattt
    12601 atcaagccat tagaaataaa gatgttaacg tcatcgaagt atttacaact gacgggcgaa
    12661 tcccggctta tcatttagtt cccttggaag atgacaaaca cctatatcca ccctactacg
    12721 cggctcccgt tattcgcgaa gcttttttaa aagctcatcc tgaagtcgaa aaagcattag
    12781 cgccgttggc cggattgatc gatgaaaaaa ccatgcaaca cttgaatgcc ttagtggata
    12841 ttaagcatga atcgccagaa aaagtggtgc atgattttct ggtagaaaaa ggtttaatta
    12901 aactgtctcc tcaggcggga gagaaatagg aagagaatca aaagcaattt gcattgtaag
    12961 aagaaagcgc ctgagccaca ccatcgagat gataaaccat aatcgctttc ccaatattcg
    13021 gatcgggatc atcaaatacc actctaaaag cacgagaatt caaaaatacc gaacgaggat
    13081 tctgactaaa gcgcatcact aagaacgggt atttatggtt atccacctgc gaaccgtaaa
    13141 gcggataagg ctgccctgca atgtacagcc gacttttaga tcggtaagaa acttcatttt
    13201 ttgtttcctt atcaagcaaa gccatataaa taatactgag cgcttctttg atgctggcgg
    13261 tggaaggaaa aacgattaat gtggtgtcgt attttggatt ccataaaatg gcactcgcca
    13321 aatcaccgtt tgtgtctgtt cccggaatta acaaaaaaca ctctttatta tttcggtaca
    13381 gtccaatctt atccaaacca tacgttccta aaaaagacaa tgcgctaata gcatctggat
    13441 aaataatcgg agaattatcg aaattatttt tttcagcacg tatgtttttc accggcatct
    13501 gtgctagagc gtgcgtaatc cattcagtag gaatggcaaa tccgaaattg cctcccattt
    13561 tagtggtaat accgattaaa tttccctgag catcgaataa gcctcccccg ctcgaaccaa
    13621 aataaatagc agcatctgtt cgtaaccacg ctccatcttt taccgggtgt ttatttgaaa
    13681 taatcccttt cgacaaagat ttctcagtgc cttgtgggtt cccaaccgcg taaacttctt
    13741 ctccaatatt aacttcggaa gaaggacgca ttttaacagc cgcaaaattg gcactgggaa
    13801 tttttaataa acaaagatct tgtttttcat ttttgaaaaa aatagttgcg ggctgcatat
    13861 taggtaaatt aggcaatttc acaacgagat caccaattaa agcaatatgg caattagtaa
    13921 ctaaagtcgt tttactggtt gcaatcgcgc tccctcgcgc tctaactacc ccggattgag
    13981 gatcgacact gtagagcgta tagacggaat cttttacttt ttgatagact tcctgcgcgg
    14041 ttaaaccaac gctaatcagc gggaatgtta tagaagcaat aaataagaaa ctagccgttt
    14101 tccttggcca atgactccat ttcataatta ccgaaactcc tccacattac tatagcacat
    14161 aaaaactgat gcactttaac tctaattaat taatcccatt caatattttc taaatgtaat
    14221 cgcaaatggc ccgcagtatt aaactgttca cgaatgaggt tatgttttcg gcctaaaacg
    14281 aattgcttta tgtgagggtt acagtagcga tagcccgtcg ccccgccaat catttcataa
    14341 aaaatattaa taagatcgta aacatcttgt tgaattttat ccttagtagg agatcccaag
    14401 tgcaataaat caatcaaatg cacttcaaat cctaatcctt ttttctttac catgatattc
    14461 tcagaatgga tgtcaccatg gtattcccct tgaaaatgaa tttgttctac gccttgagtt
    14521 agggcgtaca acaggtgtaa tgcctcaaag ggcaagagac gctttccttt ttgacgagcg
    14581 atgtaactgg aaagcacttc tccgtcgacg aagtcagaga ccagaaaatc aattttcttt
    14641 tttttgagat aaatgatgtc gtgaaaatga tattgaataa caatggggca tttacgtaat
    14701 ttatataatt tttttgcgta gtggatatgg ggattctcac cattggcctt tcgatgataa
    14761 aagagtttcg ccgctcgaat aataccggtt tttcgctcct ccaccttgta gacctcgcct
    14821 tcccaccctg aacccaaata ctccagcacc cgatagttcc gccctaatac cttgcccttc
    14881 ttcaaatcat aaaagtcagc cacactaagc ctcatataag ccattgacat taagccgaat
    14941 aagatagccc ctcagcagct aaaaggaaag cggcggatac acttgtttaa tttttgtcca
    15001 aattttggta tgatagatct ttagccagaa atgtaactcc gactgagtcc caccgagggt
    15061 aaatcgatga taaaacgact gattgccttg tcaataacct tgttcctccc actccttggg
    15121 gtagccaata cggacaatgc cttgcaaagg ttagtggtaa cggttgaaaa tacgaccaat
    15181 aaaacattga cttaccgaaa catttacgag cctgcgggaa ctattaaaaa aatagaagtt
    15241 gagcacactg tcttgttacc tggtcagcgc tccagaatcc ttatttttgg tgacggcacc
    15301 ggcttaattg catccgttaa ttttaccgat aacgatgcaa acgaactcct ttttgaattc
    15361 aatgaccccg cacaatacta tcaaggggga tacacagatt tcaaaactac ggctcaacac
    15421 ttagcgacga gtacaacaca ggttcacaac cctgccaaac cctccgcaaa gcttttgctg
    15481 tggacagaaa tcaattatca ggtcagtaat gcttaaaagc tgttggagcg cacacgatcg
    15541 ctatctctta gcaagagcct agattgcccg aattaattgc aaatttcagt ggggggacta
    15601 tatttgcaat gttaatagcg gaaaggaatc cctatgctaa aaaagataca tgcttatatt
    15661 gttgatgaat taatgttttt gcccatcctg attgtcaatt ggagcctgtg gatcgtcagc
    15721 ggctttcaca aggtaagccg gatcattaca aaacaaattt gggtcgctcc aaatgggtgg
    15781 attccttggt tgcatacgca ttttcacggt acgtttttag atcctttcgt agtacccctt
    15841 ttctttatac tcactttctt gcaagtattg gcaggacttt tattaacggt tgccctattc
    15901 aagcttgagt ttttagacta ccggaaaaaa gattttttca aagccgggtt gtttgtgggc
    15961 gcctttacga ttgccgtaat gtcatttgga caaaacatag cgaatgcgga tgaagatata
    16021 tttcagctat cctcctatct gacaacgacg ctggtttctt atttattttg ctctatccca
    16081 agctgattcg tcctaaaaag tgagaaggcg gagttggaaa caccgatgga ctttgttaat
    16141 ccttgctcga ccaaattttc catacctttc caagtggtag cacgtagggg ctgagcttgc
    16201 gaagcccaac aaaaaatgca atatcgtaaa gtcttactca agcgttcatt gttacgtggc
    16261 taaaggtatt ttacttgcca actgagctgc tgaacttgat aagaaggtga ttgttttgga
    16321 aaataaaatt ttacactgtt gggcttcgca agctcagccc aacctacgcg ctaaatctga
    16381 aagtcaggaa atcaattacc ctaggctttt cataaatacg ggtagtctat acttaaaaca
    16441 aaatggtaaa gttgcaccag agtcctattc ggatttaagt aaaaaattca atgtgtgatg
    16501 gactaagaaa tttatttgaa cttttgttaa atgtttcgca tcatattcaa aagttaacct
    16561 taatttatct tcaaaaagat gatttattgc ctgataagta aaataatttg ggttattaga
    16621 ataattataa ggtccgatac cgaatgaaaa ttttaaaaat tcagctgact tcggcaatat
    16681 tatttttctg gaagaaatgc taatcgtagg gaaatttaat tttttcagtt ctttataagc
    16741 agttagatct ttagcttttt cgatgtctga aatagaagat tttaactttt caaaaggagt
    16801 gtttttagaa atgttttctt caatatctct attgagatat ttggcaattt cccaaaaatt
    16861 aatggatttt gataccacca atagcgtgtt tatctctgaa tgataatctc ctaaagagtc
    16921 ttctaattta gtttttaata aagaacgtaa attaaaagct gttcgaaaat taatagtcat
    16981 ttgtgattga ccataataaa caattaaagc cgaagccatt gctgttaaaa ccgcattatg
    17041 tatactgact tgatattttt tacagcgctc taccaaagtt aatgtatctg tagcatttac
    17101 ttcgatatga ataaattcca tgccggtaaa ttttttgact gggggtccac ttaataccct
    17161 tttaatattt tcatcgagag cccgattttc atcgggcgat agatttaaca catctggacg
    17221 gttaagtgta tgtgtttttg aagtgttagc aacatttggc gacgtcatta tttttataaa
    17281 atcagaaata aaataaacaa aagacatacc atcgacaatg atatgatcga ttgaaaatat
    17341 cagaacgcat aaattattgt atgttgcttt tgttaagcgt aacattaatt ctttttgtgg
    17401 gtcaaacgct ttgcggaatt cctcgtacat aagatcataa agttgtttgt tgttaattat
    17461 ttccccttta ttttgaaaaa ttatttcttt ttctggatgt tcttttaatt gtataccatc
    17521 attcaattca attgtagagt taaatatttt atgcttttct ttaaataatt ttaaactttg
    17581 gattagttta tcatccggta tttcaatgca aaaacccaat gctaaaacac tattgtgttc
    17641 aattaaataa tgccggagaa agtcaatttt ttctacacaa tttaattcat tttctttcag
    17701 taggcggaac attatttttt gtttctctcc attatatgca attgggtgtc taataaatct
    17761 gctaattcac ccaaattttt ttcttcagaa aaataagata aaggtaattt aagatccaaa
    17821 gtttccataa cagaaataat aatttccgcg cgatccattg aattagcgcc aagcatacgc
    17881 agactatttt gtggttgtaa ttgttcttgt gtaatatcag gtaatatttt ctgtatagta
    17941 tctgttagag caacccatgc acgttttttt gtattcacaa ctttctccat tacttttctt
    18001 taggaaattt tccataatta acaaaattta gaatattctc tctaacccaa ggtgtttgtg
    18061 ttagtctttc catttcagcg atagctcttg actgtgtttc agcagtgatt ggccataatt
    18121 ttgtataata actttttaat ccttcaatcg tgcgtaaatc aatacggcta atgcgcaaga
    18181 cataggagtg aattttttta gcggctcatc acttaataag tcaattaatt gtaaacgata
    18241 ggcttctttg gcatcgatgg tttcggtagt aaaacccaaa cgataagcag cttgaaatcc
    18301 gacacgtcgt attaaatatg gtgttacaca aacaggcaat aaaccccaaa tggcttctga
    18361 caaactgaat tggctttgag aggtcgcaac cactaaatca ctgcttgcaa ctaaacccat
    18421 accacctgca atgaccgcac cctcaacaca actaattatt atgcgtggaa acgtaacaaa
    18481 gcgatgtaat aattttatat aaagcgtatt atccgatggt tgacgcgatt tgggcggttg
    18541 taggttcgta aaatccatac cggtgcaaaa cacccctatc tgtccttgta aaataattga
    18601 atgaacttcc ttatcttttt caatttcatc taatgcggcg tgcaattctt gaagtatggt
    18661 tatatccaaa ctatttttta tttgtggtcg attgagcgtt actaagtagt aaagcggttt
    18721 tttttcaatt attattgttt gataattcat tgtggctaac tccaacgata ataacgctta
    18781 taattttcga ttttatctag tattaataat cccttattag caaattgtct ggtatatatt
    18841 tcctcaaaag gtgtaatatc aacgtttttg tttttaacac caaaaaacca ttcttgatta
    18901 atatcaataa ttttttcata ggctaacata tccagcaaat aacgattttc taatgattgt
    18961 ttaatagaca aaattcctaa tttttcttta gcgatcggtt gcaaaattcc agaataaaat
    19021 tctgcacaac aacccgagcc ataagaaaaa ataccaacac gtttaggatt gataaaatcg
    19081 gtattatcaa taatgccaca caatgctaaa tagactgtgg ctgaataaat attaccaacc
    19141 tgttcacaat aaactaaaga aggcgctacc cgcttttgaa aatctgcttc tatgaattgt
    19201 gcgtcagtat aaccattttt tctaagcagt tggcgatgtg caccttttac catacctgca
    19261 aaaggcgtat ggaatgcaaa atagttaaag gttgtttgaa tatttatatc ttccactttt
    19321 tcacaatata tcctgtaaca attatctaaa caatcaagat acgataacaa cgacaaatca
    19381 ggattacctg tttctaaatc aggttctgga cgacaggtat ccataatttc ataaccataa
    19441 taaccagtcg caccattgtc caagataagt atttccggat ttttgctaat taacatggct
    19501 actgcaccag ttccttgaga aggttctgca taagtttttc tcgccgcggc tcgtgcagca
    19561 tcggttgcaa taatcaatgc tttaacttgt gaagaaggct gggaagacac ccatgctgca
    19621 gccatttgta aagcagcagt tccaccataa caagcctgtt tgatctcaaa taatcggcaa
    19681 tttttcgata gatttaaata aggataaata taagtgctaa gtgattttcc aaaatctaaa
    19741 cctgtttcag tagccgtaat tagtaatgca atctggttac gttcagattg agaaagtggg
    19801 tcaagaatcg gttttgcagc gttcactgca ctagttacac tatcttcgca aggtaaattt
    19861 acagattttt tctgcatcat taaattatca aaacgggtta aatctaaatc tcgtgctgca
    19921 aacaatgttt taatatctaa cgatgcttgt ccacaatatg cattgattga ttcaataccg
    19981 attttagtag tcatatattt tcattcttcc ttttctaata agaggcatgt gtgaataccg
    20041 aaaaaaccaa aactattact taatgcataa tgattatgaa tgttttctac taattttttt
    20101 cctacccaat tagcctgcaa atcaataggt tcatctaagt taatattagg atgcaaaaaa
    20161 ttatttttca attgtataat cgttgcgatt gcttcaagaa tgccagcgct atttaaacta
    20221 tgtccaatta aactctttgt tgaattaagc caaactttag gtaaatgttc agcaaatatt
    20281 gtgcgaatgg cagccatttc tgtcacatct cctaacaaag atgaagttcc atgcgtatta
    20341 agatacgtga tgtcttttgg agataattgt gtttgagata atgtttgtcg catcacgcga
    20401 acttcagcgg ttatatctgg tgcggtggat tgagtggctg ataacgccat cgaaccactt
    20461 agtatttttc cgtaaactgt agaacgtctt tgagtgggtt tttctttttc caataaaata
    20521 gcgccagccg cctcccctaa aataaaacca tctcgatttt tatcaaaagg tcgagaggct
    20581 ttgttcggat gatcaataaa atgcgcgcca cctaatgccc cactattgta aaatgcttga
    20641 atagcaattg gagaaaaatg cgtaaagtta ccaactacta aacaggcatc gaggctttct
    20701 tgctgcagca attgctgagc ttgaattaaa gcaatattac cacttgcaga tgcgccaccc
    20761 gcaacaaaac ccgctcctgt aatgtttaat acttcactaa tcactcccaa atgatagctg
    20821 tcaaaacatt gagtaatcgc tttgggagaa agataagttg gattattagt aaaagcttta
    20881 taatatttaa aattcaaatt aggcagtaga ttatcgccag taactacaag acctactcga
    20941 tttgacaatg gagggtgatc cataaaaccc gcatccttcc atgcctctac tgcggcagct
    21001 aatgtcactt gcaactcata aggcagccga ctcaccccag gtagggaaga cgctattaaa
    21061 gtctcgttga aaccttccaa ttgagccatt aatacaggaa attccaactc tggatagttt
    21121 gatactcgct taatagaaca gtttccggct cgcaatgcgg cagaaaaagt cttcgtgctt
    21181 aagccaatac tcgtttgtac acccagccca gtaatgtaaa cagggaacat catcattttt
    21241 taccatgctt ttcttaacat attaactata atagtatatc tagtacagca aatgtaggta
    21301 agtgctggat ggatggatgg agaattgata tgcgcctctt caatgcaaaa ctattttacc
    21361 gattaaaaaa tttacttttc catagcaatc attcaatttc tgctgatccc atcgccatca
    21421 ttggtatggc aggtcgctat cctgatgtta aaaatctaga agatttttgg caaaaattaa
    21481 aaatagggtg ggatggtatt acagaaatac cagctagtcg ctgggactgg catgaatatt
    21541 atctgccagg tagcgcgggg aaaaatcttc ctaacaaaag ctgtagcaaa tggggtggat
    21601 tcctcactga tgttgataaa tttgatgccc tattttttaa catttctcca aaagaggcga
    21661 aaaaaatctc cccagaagaa cgcttaatgt tggaagttgt ctgggcactt ttagaaaaca
    21721 gtggctatac ccctgaaaaa ttaaaaaaac aaacgaatgg ttctgtcggt gtatttgtcg
    21781 gcagcacttg gaatgactat cgtttactat gcgggatttt ggggaaatcc gcagaatatg
    21841 gacttgcttc aattggttta attcccaacc gaatctctta tttttttgat ttacatggtc
    21901 caagtgttgg tgttgatacg ttgtgttcgt cttcattaac cgtattgcat ttagcctgcg
    21961 aaagtctaag acgtggagaa tgccgttatg caattgttgg tggcgtaaat ttaatattac
    22021 atccttcgaa atatttactt ttaaacgcgg ctggattttt atctccgagc ggtcattgca
    22081 aaagcttttc tgcggatggc gatggttttg tgcctgcaga aggtattggt gcagtcatgc
    22141 ttaaaccact aaaacaagca caagctgatg gtgataatat tttggcaatt attcgtggta
    22201 ccgccgtcaa tcacggtggt aaagcaaatc gatatactgt tttaaaatta ttttctggaa
    22261 tacgaaaaaa taaagcagat aaaaataata aagctgctga aaaaacgaga catacaggtc
    22321 ctcaggcagg ccctaccgta ccaaatcccg tttcgcaagc agaagtcatt caacaagcat
    22381 taaagaatgc aaatctaaca cctgaacaga ttaattacat tgaagcacat ggtactggta
    22441 cggaattagg tgatcctgtt gaaatggcag gattatgtaa agcctttgaa aaaagaatag
    22501 caacgacaaa atgtccaatc ggtgcagtta aaagcaatgt tggccatatg gaagcagcat
    22561 ctggtatagt ttctttaata aaagtcatcc tgcaatcgca gcataaacaa ttagtgcctt
    22621 ctattcacgc taaaaaatta aatccattga ttgattttac acacacgcct ttttacattc
    22681 agcaagaatt aagtgattgg tccccgacaa aagatgaatt acgtcgggcg ggaattagtt
    22741 cctttggcgt tggtggcagc aatgggcatg tgattataga acaagctccc gaaaaagaaa
    22801 tttcgtcacc cccagaaaag ccttattatt tactgacttt ttccgcaaaa ctacaagaat
    22861 ctttacagca gagaatgaac gattttcata attatctcgt gcaacaatct tcattggttt
    22921 cattagcaaa tattgcgtat acattgaatg caacacgagt tcactttcca gaaaaccgcg
    22981 cggcaataat cgtgagctca acagaagaaa tcattcatac gttgaataaa ataaaatcaa
    23041 acgaaaaacc agagaattat ttattgcaag taataaaaaa atgaaaaaca caacggcaaa
    23101 tgaagtgctg aaaacattaa tagaaaaact gaaaaccaaa tcgttaacac caactaccta
    23161 ttacgagtta ctgaatgcca ttggagattt gtatgtacag ggacatgata tagattggga
    23221 tgctttctat caaagtgaat cacatcaatt gattatgtta ctaaattatt catttttgaa
    23281 aaaaactcat tggtgcgata ctaataaaat acaaagctcc cctcctcaac cgttgcctgg
    23341 tgaaaaaata cagctatccg agttagaagt gaaaccacca caaatagaaa atgcgccctc
    23401 agttcctgat aaaccagaaa ttctttcacc aaagatgaag gaagataatt tgcgacaaaa
    23461 cacgaacgag cctgttaatg aagcaatcag aaaaataatt gcagaaacat tatttatcga
    23521 ttctaactta attcatgata cagaattttt tcaagattta ggtattgatt cgattctggg
    23581 cgtagaaatt gcccaaaaaa ttcagaaaaa atttaacata gaattaaatg cagccacgct
    23641 ctatacgtat tctaccgtct cgcaactagc caatttcatc gttcagcaag ctaacatacc
    23701 atcaacgtca gatgaacaaa aagaggtaat gcaaattcaa gctcaagatc aagctttatc
    23761 gataagcata tctccctggt ttcggacaac tttgttatca cgacctgata tagatttgtt
    23821 ttgttttcac tgcgctggag gtggtcctgc tttattcaat ggttggcgtg tattattgcc
    23881 aaaaaatatc ggtttgcatt taattgaatt accgggtcga gaaaaacgta taggtgagcc
    23941 actagaaacg aatgctcaaa agttagtaga aaatattggt aatgaaatta ttggagccaa
    24001 attgaaacgt tatatatttt tttctcacag cctaggtgct ttattggctt tttacgtagc
    24061 caaatattta caacaaaaaa aggtaaattt acctgaaatt atttttttat cgtcatgtcc
    24121 ttctccggaa aatgatatag gactcctgaa agacttcaaa aaaaattcgt tatcagatca
    24181 aacgttatta gaaaaattgg atgaattagg tgttaatgga ataccctcag aaattcgtta
    24241 taattctgat gctttaaaaa tttatctcaa catactgcgc gccgatatgg atttagaatt
    24301 taataccccc tggtttgaac aattattagc aactgatcga ttgtctagta ctttcgttat
    24361 catggcaggt gaaaatgatc gttttatttc attaaaagaa atggaatcat ggaaagaata
    24421 tacttctgga tcctttttta aaaaatcttt tcctggcaat catttttatt taactgttga
    24481 taaagcagca gtgtgcgatt ttatcgccaa tatgatcgtt acctaatgct tagctgcaat
    24541 ccgcagaaag taagctatat ttctattgtt ttccttatgg aaaatataaa cgaaattata
    24601 aaagaacttt tatcatatga aaaccatcat aagagccagt gaatatagta aaatattttg
    24661 gtttgagagg ctgaatctgc cagagaatca acagtatttt tatcatttat atggtgctta
    24721 ttgttataaa aacgatttag atatatatcg tttgaaacaa gcactccaag ccacagtcaa
    24781 tactaattat aatctgcgca gtaattttga tgagcaagct ggaactttac aacaaatcat
    24841 tcatgatcat gtacaagctg ttttagaaga acatacagtt gaaaagcaaa ttgaaagtaa
    24901 agccattgtt caaaaaacaa taacccagcc atttgactta gcgaaagatg cattatttcg
    24961 atttgcgtta ataaatagta aatacaatca aacggtgaca ctattggttg ttttccatca
    25021 catcatttta gatagcactc aatatggtaa actgatgcaa tgtattagta ataattacca
    25081 ccatgctcca gaccttaata taacagataa agatgaaatt aatcatcttg aagattacat
    25141 tgcttgggaa gaagagaaga tcaaaaatgc ggatgtacaa tattgggtat caaaattaaa
    25201 aaaatatcca ttaaataaca atttgcctta tcaaacaata gaaataaaaa gaacgcaatt
    25261 aaaacaagtc tcaaaattgt atgaacttga taattcactt tacagcaaac tgtctagttt
    25321 tagtaaaaaa agtgggcatt ccgtattcaa tattattaaa acaatttggg caatgctaat
    25381 aagcttgtat tgtaatcaag ataaggtagt cattgcttat ccatttaata cacgtcctaa
    25441 gcaatttaaa gatattaagg gatcattcgt taatacttta tttttccctt ttgagagaaa
    25501 gggaaatttt attgatcaac tcgacatgca aaaaaaggag ataaatctat cttatattaa
    25561 aaataaatat attagtacag ttgatttggt tgctcagtta ggtaggcata atgcggcatt
    25621 taatgtggcc gtgtcgcaaa cagacccccg tttttatggg ccaacattga acgaatcatg
    25681 tacttatttt aaaactacaa gtattggagc agcagaatta tttcttttat ataaagagaa
    25741 tgaagagtgt ttacgttatt cattacagac attagataaa ttatttgatg acgacttttt
    25801 ggatagagta gcacaacatt ttaaaaactt acttaggaag gttttagata atcctaaaat
    25861 aaatattagt actgtttctt gcttgagtga gtcggaatat aaaaaaattg ttaatcagtg
    25921 gaatgaaacc gatcaatttt atccaaaaga tcagactata catcagctat ttgagttgca
    25981 ggctgataaa atacctgctg caattgcagt agagtatgaa aatcaacgtt taacatatcg
    26041 tgaattaaat tcaaaagcca atcaagtggc gcatcatata cactattatt atcaaaaaat
    26101 aatacaacaa ccatttttag cagatacctt aattggaata tctgctgatc gaagtcttga
    26161 aatgatcatt gggatattgg gtatacttaa agcaggtggt gcttatacac ccattgatcc
    26221 tggctatcct aaaaatcgag tagaatatat tttagaaaat acacaaataa aactcgtatt
    26281 aactaaaaaa tcattactaa aaaaatttag aaataatatt tatttactcg cattagattc
    26341 cgaagaatgt ttaagtgcag atgacgataa tttagctata aacactacag ccgatcactt
    26401 agcctatgta atttatacat ctggtactac cggcgatccc aagggagtta tgattgaaca
    26461 taagagtgtt atctcattag taaaagaaaa tggatttttg aatattcaag cgaatgatgt
    26521 attgcttcaa ttagctagcc ctatttttga tgcagccatt tttgaaatat ggggagcttt
    26581 attaaatggt gctaaactta tattaccgaa aggaaaatta gatatactca atagcattga
    26641 tcaatttaaa aaatttctaa caaaaaataa aatttctatt ttatggttaa ctaaaacact
    26701 ttttgataac ttgtatcaac ttgataatac attgttcaat tctattcgat accttttaat
    26761 tggtggagaa agcttagctc cttctttaat tcaaaaatta tgttcacaaa aattgcgacc
    26821 ccagtatatt ttaaatgcat atggacctac agagggtact acttttagca ctatttattt
    26881 ttgtgataat aggctgtacg gtagcgtccc gattggaaaa ccatttaacg cgagaaaagc
    26941 ttatattctt gataagtcgt tgaatcctgt agcaattggc gtaattggtg agatgtatat
    27001 tggaggcgca ggattagcac gtggttattt gaatcagcct gaattaacag cgaagtgttt
    27061 tattgcaaat ccttttgcta ccgcagctga ccaagcaaaa ggatatacac gattgtataa
    27121 gacaggagat ttggtgcgtt atttaccaga tggcaatatt gaatatatgg ggcgtagcga
    27181 ttttcaagtg aagataaatg gatatagaat tgaattagga gaaattgaaa cggtattaaa
    27241 ccgttatcct gctgtcaaac aagtagtggt gctggtcaaa gaacatgaag gaaataaata
    27301 tttagtggct tattatgtgg cagaaaatga attcaatgca acagatctca aaaattattt
    27361 atccaaaaat ctgcctgatt atatgttgcc acatgcttat gtttatttaa aacaatttcc
    27421 actgactatc aacggcaaat tagaccgtgc ggctttgcct gagccagctc tcgtcaatgc
    27481 tgatcaatac gttgcacctc gcaacgaatt agaagagaaa atggttagta ttttggaaga
    27541 attattaaaa gtaagaccca ttggtatcaa agatgatttt ttccgaattg gtggaaattc
    27601 cattttagct ttaaaatttg ttgcaaaatt gaaaagtcaa ataaatttat cgcttaaaat
    27661 atctgaattg ttctcgtcta gagacattga atctattaca gcactcgtga ataacagaaa
    27721 aagctatcag ccgattgtat cgatgaacaa agatagaaat caaaaaaata cattatttat
    27781 gattcattcc ggtttttcgg ggtgtgaagt ttataataat ttagttactg agttagataa
    27841 tgattatcat tgttatggaa tagataatta taatttgtat catgataaaa aaattgatag
    27901 tttacacaag atagccgccc tctatttagg gtatattaaa ttatgtcaaa aaaatggtaa
    27961 ctcctatcgt cttttgggtt ggtcatcagg tggtaccatt gctcttgaaa tagctgccat
    28021 tttagaaaaa gaaggcgtaa aagatataac tgtttattta ttagatacta ttttatcaga
    28081 tgctacgatt cgacgattga gccctaaagt agatagttca tatctcaaag aattggaatc
    28141 taaaatgaag ggcttcggtt acgaagacag ttatatcaaa aaagttttat cggtttgcat
    28201 tcctgaatca ttaatttctc acgatgttat ttccaaaatg ctgaatgaca caaatgtaat
    28261 tctgtttaag gcattgaaag aagatgctaa gcgagatcaa tggggcttgg aaaaactcac
    28321 taaatatgca ttatcattaa aggataataa tgtaggaaat tattgtagaa aattaaccgt
    28381 cataaatgta aatttgtctc ataagcagat gccattgggt caatatctta agtttatgaa
    28441 gaatactgga gaacattaag cacagataaa tagtctcata gcaaaacgag aaaaagccct
    28501 tcaaatggaa acttctattt ccacttctat tatcaagtgc aaaaccaaag gacggcgcat
    28561 tcaatttttc aagtgcgaat ttcccctgag gatttaagag ttatcttgta ctcataaaaa
    28621 gcttcttttg ggatgcgata atctaaacac cgcattaagg tcaggccgga actaaaactt
    28681 aaaacttgtc ttaaaaagaa tccagaaact tcttcaatac cagcaattca gtaggttggg
    28741 ttgggcttcg caagctcagc ccaacctacg cgctatccca agctgattcg tcctaaaaag
    28801 tgagaaggcg gagcaacttt aattatggag aatttatttt ttggggaaaa ccccttgatt
    28861 gactgcattt ttcatttttc ttctatttac ttcatcgctc ttcgtctcaa gaaaactcct
    28921 caccgaatga tgctgatttt ttgttgcaag acgatatgca gcaaaattgc tggcttttaa
    28981 agcttctaat tgtaatggag aaggtataga ttcccaaatt aattgtacta tttctaaata
    29041 ccctttatcg gcagcataaa taaaagcact aaaatcctta cttttaagaa gcgatatttt
    29101 tagttgcttt gattcaaccc atttcactag ttgcttgaga atttctacgt gtccgttttt
    29161 tgcagccagg atgaaagagg cttcaaatcg attttcgatt aatttttttt ggtttgaact
    29221 actagataaa ctccataata attggacaat atccagcttc ccgctttgac aggcccgctt
    29281 aaaatgactt aaattcaccc tataaaaact tatcgataca ggaagtttgc cagggtcatc
    29341 taaaagtaaa tgctgtgatg gtttaggcac aagctccagt atacgctgaa ccgatgaaat
    29401 atcctgagaa cagcattctt caaatatata taaaatgcag ttcctcagag aggaattcca
    29461 aataattttc ataaaagttg gattttctgc aataatatct atacagtatt gaaataaata
    29521 ttcttcttct aagattctct ctacaatttt aatatgttgg ttagctaacg cggctttaaa
    29581 gccctcacca tttctatcta aaaaaacaga tatgacggct tcatctgcag gtattttatc
    29641 agtgattgat ttaacataat taaaaataaa atcgattaca tcaaaatgcc catttgcagc
    29701 agcaacatga aaacaagcat agtgatcaaa cttaataatt tgatttttct gctcgagcga
    29761 aggagaagag aaggttttgt taacctcttc aatgttacct aaactacaag cattaacaac
    29821 cctagaagaa agggaatccg gcatacgata acctacttat aacaacatca aaaatcatac
    29881 cagaattcga ttaacaaact attaaaaacc ccatgatttt aaatttgtac cgaacaaaaa
    29941 tcataaaaag tagcccgtat gaagcgtagc gaaatacggg aattaccatt attttcccta
    30001 tattcctctg cgcttcacac ggctacttct aataaccaat attatattgg gaaaccctgg
    30061 gttttggctg aaggtaaatt gccgttacta tatcacctgg atagtcgcaa gtgtttaaaa
    30121 tcttccccgg tccaatttcc tggtaattca ttaataaagc tttttacctc ttccaccgtg
    30181 ctgtacccgt tgagtccacc ccctaaattt aaaggcccta acatttgttt acctaggggg
    30241 tcgggagcag ttacacgcaa atgctgtgat aaaagaggtg aagcgactgg tatatatcca
    30301 agacagccta gtactgtctt tgtattaagt gcagggttat atttttgggg attttcttca
    30361 ctggtataaa taaagctgaa acaatcacgc tttaattctt cacaagcttg cccaaaagtg
    30421 aacaataact tatcgtaata gggacaaccc tcaaaacccg taataacagt tacgaaatta
    30481 tctttgcctt ccctcaatgc tgtctcacaa ccgacaggat ttaaattagg caatggcgtg
    30541 actttagcgc tggccatagt ttctggattt gaaaaaattg aaaatacagc taacgatcgt
    30601 actaatgtct cagtaaattt ctcacatgca gatttcctac gcataaaata ctcccttttt
    30661 gaaattatag ttaaaattca attattcgag tagtttcatg atttggcgct tccagaacct
    30721 cccagcaggc atttcgaaaa caaccgcatc catccatcaa ccatagtatt ttattctccc
    30781 attgttaaat ttaacttaat ttttgcaaaa caattcttgc ctcacagaga atctccacca
    30841 agttattaaa agaggattaa agggaacttt ggaagaagga acccttttga cgaagcccgt
    30901 agcccgtagg ttgggctgaa cttgcgaagc ccaacaaaca atgcaatatc gcagagcctt
    30961 actcaagcgt tcattgttac gtggctaaag gtattttacc tgccaactgg gctgttgaac
    31021 ttgataaagg tgattgcttt ggaaaataaa attttatacc gttgggcttc gcaagctcag
    31081 cccaacctac gcactttaca aagcagtacc ccacttttcc attttatttc cacaatgatt
    31141 caagtgtgta aggcgaacct tttattgtaa aaatgctgcc atcaatgagg cggcaacctg
    31201 agtttagtgc tttaatcgcc tcaagatcct cagcggtcaa tgcgatatcc agcgattcga
    31261 agttttgttg taatcgcgcg ggattaaccg atttaggaat aacagcgaca tcgcggtgca
    31321 actgccacgc aattaaaatt tctgcgggtg tggcattatg cgcttcggca atcgcgttta
    31381 ttactggatt ttccaataaa gaaggttcat ctttagcttt gcgtgtttcc ggacgatcgg
    31441 ttgagccgag tggtgaataa gcagtcataa ctatattatt ttttcgacaa aaatttaata
    31501 gctcattttg cgctaaaaaa ggatgacttt cgacctgatt aactgtaggt ttaaaggatg
    31561 cttgatttaa taactcttcc attcggctaa tcgaaaagtt ggaaacaccg atggactttg
    31621 ttaatccttg cccgaccaaa ttttccatac ttttccaagt agaagtaata ggtaatttgc
    31681 ttaatggaat aaaagcgtcc gcattttcag ggatgttata acccaccgaa tgtttttgcg
    31741 ccaccggcca atgtattaaa tacaaatcta aataatccag ttgtaaatcg tttaacgttt
    31801 ttttacaagc gggttctaca tcttcaggcg catggtcgct attccacaat ttcgacgtaa
    31861 tccacaattc ttcgcgcctc acatcacctg ccttgattgc atcctttaac gccttaccga
    31921 tggttggctc attaaaatag atgggagcac aatcgatatg gcgataacca atctcaatgg
    31981 ctttgcgtat agcggtgtaa agctcgtttt cgggtgattt ccaggtacct aaaccgagaa
    32041 gtggaaaacg ttggccggaa gatagagtag cgtatttcat agcattctct tgtagttaat
    32101 aaggcgtcat tctaccaggc ttattcggtt gcttcaaagg caccaataat gttttcatcc
    32161 aggattttta attctggcat aaaatccaag tccatcgggt attttagccg ttgggcttcg
    32221 caagctcagt ccacctaggt gcatttttgt taaagaacgc ttaaagataa ggtattttat
    32281 caaatctcat ttgcaaggaa aaaccgccta tgtcatattt ttgctcgtac aaataagcgg
    32341 aacaaatcat gctttcaatt gaagttgaag aaaagccacc cttgctcaat gagcattcta
    32401 acagagacgc ttgcccctat tttaatttag ggaggctgct gcgggacatc aatcgactgc
    32461 ttcctacatt gccttacgtt ttcaaaacta tccactctat tatgggggtt tcgcgatatt
    32521 atggtataaa accgataatg cttttgtacg acttgattga aatagttaat tcagatgaaa
    32581 agagtgattg cggccgcgtt aacatcaatg aattgctggc gatggcattt ttttcggctg
    32641 aaaaagaata tattgcgata ttggaattgt gtttatcggc acttatcact gtgcaagaaa
    32701 aacgtttttt ttccagttta tatctgattg cggcatccgc gactaatgca gacgttttat
    32761 catgtttgga cgttatggaa attccaatcc caactgaccc cgctgctcgt agagcatttt
    32821 taagagcact ttatgaaaat cgtactatat cacatagtat ttatactaaa tattactgca
    32881 aagtccaaca ttactgtaaa ttgtttgcgg tggatgcccg tgaaatcacg ccagatgata
    32941 ttttgaaaaa cagaatattt caattatatc aggatgaaga tattgagaaa ttgttggatg
    33001 attttcagcg ttacttccat caaaagcgat tcgataaaat catgaatgta ttgcacgctg
    33061 tggaaaatcc aagtttaatc aatcgtatta tgcttcattt attgggcctt acgaacattg
    33121 aggtctccgc aaaacaattt ttgttgacgt ccctgagttt tagaatagac agttggttta
    33181 gttttttgga ggctattaca tttatttctg atgatgaacg acaatattta ttgctcagaa
    33241 attttatgca gtcgattcag actaatgcgg gcttaatcaa ttttctgctt attcaggcag
    33301 aatatgaatc tagcatgata ccggaacaaa agcatagcat taaggactcc ttactatatc
    33361 gaatattagc cattttatgt agtgttaaat ccgatttttt actagtcgat caacgacaaa
    33421 aacgcttttt gttaaatgcc atcgatctta ttgccatgga tgctgatctt tccactgcca
    33481 tacgaattaa aaaaaataca cggctttgtg ggacaggtac ctaatttcgc ccaatacacc
    33541 aacggttatt gacgaaatcg ttttgaccta tttatatcag ccctatgact ttaactctga
    33601 ctattgttca ggaccgctga aagcagaatt tattacgatg ttttcgccac atttaatacc
    33661 tgattataaa acataccgtt atcggcgtct cattcaaatc ctgtataacg tcataaatgg
    33721 aagaatcgga atagacaaag acacctatag tcgtacaagt cataagtgtg gtttagtgtg
    33781 gcgtatggag gaggcagtca ctttgctatt tatagccgga gtgacaatag gtccatttac
    33841 ctcttttttc tgtgctgcca ttttagggta tatagcaaca atttttgtcg accgtcttac
    33901 ctattctagg ctagactatg tcatcacaca ttattctttt cgctatccct ttttaagaga
    33961 ggatattaat agagttattc ctgatctggc aggtaatgag gatatcgcaa tattcaaaaa
    34021 aaatttttac caattgccca ttaacaaggt aatcgatcga ttagaacaaa agtttttcga
    34081 aattacccgt gagcggaaaa tacacgaaga tcgtgatgaa aagttcgtaa gcttgggctt
    34141 cgcaagtgta tagcccgtag gttgggctga gtttgcgaag cccaacaaaa aatgcaatat
    34201 cgcagaggct tactcaagcg ttcattgtta cgtggctaaa ggtattttac ctgccaactg
    34261 ggctgctgaa cttgataagg gtgattgttt gggaaaataa aattttatac agttgggctt
    34321 cgcaaactca gcccaaccta cgggctacat agcttctaca tcaaatttcg actacttagg
    34381 attaacgata actgtttgat tttaaatgcc ggtgcgcaga ctcgaactgc ggacctactg
    34441 attacgaaac cggactttta cttacaactt acttaaaatc aataccttgc gatgcgattt
    34501 tggcagaaaa actgcctagt tctgcctatc caggcaataa atcagcctaa ctatgttaca
    34561 aattccctac atcgactaaa atcttcacct tcttctacaa tgctttgagt gacggggtaa
    34621 aatgactatg gaacaatttt catcttctga actaaaaacc attttgcact caaagcgcgc
    34681 gaatctgtat tacttggaac attgtcgagt catgcaaaaa gatggtcgcg tgctgtatct
    34741 cactgaagcc aaaaaaagca atctctattt caatattcct attgctagta cgaccgtaat
    34801 actgttaggc acaggcacct ctattacaca ggctgcaatt cgaatgcttg cgcaggcagg
    34861 tgttttagtt ggattttgtg gtggcggtgg aacaccgttg tatatgggga atgatattga
    34921 gtggatgaca ccgcagagtg aatatcgacc tacagaatat ttgcaaggct ggatgaaatt
    34981 ttggtttgac gataaaaaaa ggttgcgcgc ggcaaaaaca ttacaacatg ctcgtatggc
    35041 atatttagag gctgtctgga aaaaagacag ggagctgaaa gtatcgggat ttgattttcc
    35101 agatagtgct atcatgcgcg caattgaagc atcgaaggct caaattgatc gttcttcgac
    35161 agtttctata ttactcaaca atgaggcgca attaacaaag atattgtata aatttgctgc
    35221 aacgcaaaat agtatcgata cttttacgcg aaatagagat tcaaccgaca aagccaacgg
    35281 atttttaaat catggtaatt atttggcgta tggattagct gcaacaacct tgtgggtgtt
    35341 aggaattccg catggtttcg cagtgatgca tggaaaaact cgtcggggcg ccttggtttt
    35401 tgatgttgct gatttgatta aagatgcaat tgttttgcct tgggcattca tctgcgcaaa
    35461 agaaaatgca actgagcaag aatttcgtca gcaatgcctc caatcttttg cagagcataa
    35521 atcattagat ttcatgttta atcaggtgaa aaaaattgcg ttggatcacg atgagggcag
    35581 tgcaccatga tggtaacctt tatttcccaa tgtgaaaaaa aagcgctttc aaaaacaaga
    35641 cgggtgcttg atgcgtttgc aaatcgtatt ggtgataaca cttggcaaac agtgattacg
    35701 caagagggct tggttaccgt taaaaaaatt ttgcgacaga cggcgagtaa aaataccgct
    35761 gtttcatgtc attggataag aagccgttca agaagtgatt tggtttgggt tgttgggaat
    35821 aggcagaagt tcaatcgtga gggagtagtc cctgttaata gaactacacg aaatttgatg
    35881 tacgctcata ctgaaaatga ttggacgtat ttgcctttaa ttaaagccct agtggctatt
    35941 gccgcacttt tgcatgattg gggaaaagcc agtcagcttt ttcaagaaaa gttaaaccct
    36001 aaaaataaag tcggatttaa gggtgaccca attcgacatg aatgggtttc gtgtctattg
    36061 ctgaatgcac tgattcaaat ccatcaagac aacagcgatc agatggatga tagaggttgg
    36121 attgaagctt taatcagcgg cgatattgat gaagccaaga taaaagcgct tacaataaaa
    36181 cagaagatta agccgttagc tgatttaccg ccgatagcaa agtttgtggc gtggctgata
    36241 gtttcacacc atcgcttgcc actaaacaaa gatgcggata tgcgggcaga atactgccct
    36301 gaaattgatg atgtcttgaa tcgaattacc caacgatggg gctatgaaaa taattacgat
    36361 gaacttgatt accaacaacg tgttgagcag tgttttaatt tccctaatgg attgctaagc
    36421 aattcgaaat cttggatgaa acaaatccaa aaatggtctc aacgattgct gacctgtgaa
    36481 ggccaagcat tgcaatccct aagtgatggt agttatcgct cagtgttaag ctatgcacgt
    36541 ttgtgcttaa tgttgggtga tcattattat tcatcccagg gtgccgatga gaaatggaaa
    36601 aatatctcgg gtctatttgc taatacagat tttaaaacta aagctctaaa gcaaaaactt
    36661 gatgaacatc tagtaggtgt tgcaaaacat ggcttaaata cagcacattt attacctgca
    36721 tttgaaagtg agccgccaat agcacaagat attgtggcgc ttaaaaagcc gtgccttaaa
    36781 gagttccgct ggcaagacaa agcggtggaa aaaatcaaac tttggcgaaa ggataatacc
    36841 aaaaagcagg ggtttttttg ccgtgaatat ggcgagcacg ggttgcggta aaacctttgc
    36901 caatgccaaa gtgatgcaag ccttatcagc tgatggtaat agtctgcgct ttattctagc
    36961 tttaggcttg cggactttaa ccttgcaaac aggagatgag tatcgcaaac gtgtcggctt
    37021 ggatgacact gaactggctg tactgatcgg ctcgcgtgcg gtaatggaac tgcatcaaaa
    37081 agctaaatta gaagccgatg agcagagctt tgaggaaagc ggttcagaat cacaagaagc
    37141 gctattggat gaagaggttg attatgattc cgccattcct gaagaagggt tcgccactgt
    37201 attgcgtgag cagcgcgata aaaaattcct ctatgcacct gtgttagtct gcacgattga
    37261 ccatttgatg gccgcaaccg aaacgaagcg cggcgggcgt tatattttac ctacgttacg
    37321 gctcatgtct tctgatgtgg tgattgatga aattgacgat ttttcaggta aagatttagt
    37381 tgcgattggt cgattagttc atttagcggg gatgttaggc cggaaggtaa tgatctcttc
    37441 ggcaaccatt ccccctgatt tagccgaagg ctgttttaaa gcttaccgag acggttggca
    37501 aatctattgc aatacccaca acgctagccc aacgattggt tgtgcttgga tagatgaatt
    37561 taatactgat gtgtcaagta atgtcggtgt agaagttcaa gatgcaatac tcgcctatcg
    37621 agagcaacac gcgaagttta tagaaaagcg cgttgccaaa ttattaaagc aaggggttaa
    37681 gcgcaaagcc gatattgctt tatgcgatgg tatcttttca gatttcgccg agaatcataa
    37741 cgatgaagat gttgtagtca acaaacagca agcttatttt aagtgcattg tcgatagtgc
    37801 catagccaaa catcagcacc accacaccgt cgataatcaa agtaagttgg ctgtatcttt
    37861 tggcgtcgtg cgaatggcta atatccaacc ctgcattgca ctagcgaact atttattatc
    37921 ggttgaaatg ccagcagata ctcaaattag aaccatgccg taccacagcc aacaagtctt
    37981 gctgatgcgt cataagcaag agcagcacct tgatgaagtg ttaaagcgta aagaagatga
    38041 gggagagcaa ccccaagcat tttcaaaccc tgttattcgt cagcatcttg atcacattta
    38101 ccaagctgaa ccgcaggtta aaaatgtaat gtttgtattg gtggccaccc ctgtagaaga
    38161 agttggtcga gaccacgact ttgattgggc agtagttgag ccctcgtcat atcgttctat
    38221 tatccaatta gctggacgtg tacgccgtca tcgtaaaact gaggtgcaat tccccaatat
    38281 tagcctgctg caatacaact ggaggggtgt tcgagatagc catcgagaaa aagccattgt
    38341 atttaaatgg ccagggtttg aagacagtaa acataggctc gaaagccacg acctaaaaaa
    38401 attgctagac gctaatgcca tattacaacg cgtggatgcc attccccgta ttcaaaagcc
    38461 taaagactta caacccaaaa agaaattagc tgatttagaa cactctgtga ttaaaagttt
    38521 attggctaac taccggagtg atagcaatgg tccagctaat ctacaaggtt atttacgaga
    38581 agcatggttt ttaacggcgt acccgcaaca actagtgccg tttagacaag gtcagtcgaa
    38641 tttgaaagta tttctaacgt ttgatgagga taagcaggta tatatgtttt gtgagaagaa
    38701 tgaaaaaggc tttcctgtac cacgtgaatt acctctcggt attagtcgcg ttcagctaga
    38761 tgataatgct agtaagcgcc tgtggttaaa gcgtaatttt gagaaagaaa tagaagcatt
    38821 gtcagagaag caagaagtga gtatgcggaa cgcgtcaatg cgttatgggg aattaagctt
    38881 tccgtattat gagaaaaata aatatgaata taacgatcag tttgggttgg taagagttta
    38941 aagaggtgct tatgttaaat agttcaattg atgaattttt taaaaaaagg aaagttgcat
    39001 ggcttaaaaa ggccattaat gcttccatgg atgaaataga agttagcgag aaagagcttg
    39061 agtgtgagca ggtttttgca ttagagcatt ggctaccaag tgctgctaaa cgagcaggac
    39121 aaatatccat atccacccac ccatgcactt ttagtcatcc tagttcacga aaaaataaaa
    39181 atgggtatgc ttcttctatc atcgctaaca gcaagcgcag cgaggatggc tatttacgca
    39241 gtggaaatgt aactgtgaag gccgatgctt taggtaatgc agcagcgtta gatgtatata
    39301 aattcttatc gcttgaaatg gcagatgggc aaacattact tagccatatt cagcaagata
    39361 gtgatttggc tcaacaactt cttaatatta agagcgagtc atataacacg ctaaaagatg
    39421 ggtttttggc aatgatcaat aggaattcag actgtgtgac aagctcaaaa attaaacagg
    39481 tctatttccc tttagataat ggctaccatc agttatccat attgtctgca tcaggtatca
    39541 tgttcgaatt aagaaaacgc atcgacacga tccgtttttc cgatgaagcc aaagcagcgc
    39601 gagtgtgcga aaaaaataat gaaatttatg atggtgatta taagcagata gtcaacataa
    39661 caaccattgg ctatggtggc actaagcctc aaaatattag cgttctaaat aatcaaaacg
    39721 gtggaaaagt acacttaatt tcaagtgaac cacccaaact aattaaacgt gacgctcact
    39781 ttccaacagt agattttttt agccagtccc ttaggtattt ccaatgcaaa gacttattct
    39841 actcattaca cgaactattt cttaatcaca aaaacgattg gaacattcgt catgagcgag
    39901 acgaatatta ccaagcaatt attgatctca ttatcgaaaa aatgtggttg gtaagaagcg
    39961 tgagtcaggt gcaatacaac ccggattcga ctcgattaaa cgaaactcaa aaaatttggc
    40021 tttgtgaagt gaataaagaa aatcgagaaa ctgaaaatga ttggttagat gatctatgcc
    40081 aagctattgc ccgttttatc tttactggct atgaaaagct tctaggtaaa aaagcattta
    40141 tattttcaga cgatgaattt aaacatattc ataaacaagt ggtgaaaaac aaggaggcac
    40201 tgcgatgagc tataacaaaa tattgctaat cccgcatctt cgtatccata acgcaaatgc
    40261 actatcaagt ccatttacga ttggttttcc tgcgatgaca gcttggctag gcgcaactca
    40321 tgcgttgcaa cgaaatttaa atgaacgtgg catacccgta acgattccgg caacaggcgt
    40381 agtaagccat cagatggatt tgcagactta tcgaggtaat gacgattatg tttcatcaat
    40441 tatcaataca ggtaatccgc ttgttccgaa aactaaaaga gagaaaggtg agccatggca
    40501 taactttgag aggccaccgt ttattgaaga agcccgttgt cacctcgatg tttctttgct
    40561 gatcgaattc cggggtgtga gccaagagca ggatgacgaa ataaaagaac aagtaagcca
    40621 cttgcttaac tgtaaaatga aagtggcagg tggagacatt caatctttta acccccctgc
    40681 tattttgctg atcgaagatg gcaacgacgc agatttacga agactttctc ggaaaattat
    40741 gcccggatat gtgctgattg agcgacgcga tttaatgata gaggccatgc aacaaggcca
    40801 agacgcgctg gatgcgttaa ttgattatgt ggcgatacac cacagctgcg aaaaaaccga
    40861 agacggcgac gtgttatggg aaagtcaccg taaaacccaa atagacaaac ctccaggctg
    40921 gattgttcca attgcgacag gttttcacgg cattagtgaa ttaggacaag ccaaaaatca
    40981 acgtgaccca gaaaccccac accgttttgc agaaagccta gtgactttag gcgaatttaa
    41041 aatgcctcac cgatttgagt cagtaacaga catgttgtgg tgttatcaag tggatagtac
    41101 taacaatctt tatcaatgtg tagcccttaa tacgattacc gaaaaccttt atgacgaatt
    41161 tggttaattt aaaactcagg agaacgacca tggctaagaa agaaaatatt gatattgcat
    41221 cagtactctc atttgaaaag aagctgatac ccagtgatgg ctatatgttt ggcacgagct
    41281 gggataaaaa aagtgaagtg acaccactta aattgcgcga aaaagcagtg cgtggaacaa
    41341 tctctaaccg atttaacaaa aatgacagca agacatttct ggatgaccct atgaaactgg
    41401 atgcagacgt tgaacgccca aatttacaac gtgttgatgc ttgcgcacta gaccaaaatc
    41461 aagacacact aaaactgtgt tttacactca aagtattagg tggtattacc aatccttcag
    41521 cttgtaataa cgcattattt aaacaaagtt acaaggccgc agcgaaaatc tatatcgata
    41581 cgcatggctt tactgagctg gcgacacgct acgctgaaaa cctagcgaat gcacgtttcc
    41641 tttggcgaaa tcgtttcggc gcagagagaa tagaagtgcg ggttaatgcc agcaataaaa
    41701 ctgttagcca aaaatgggca tttgatgcga caaaattcaa cctccataca tttgactcaa
    41761 gcgatacgtc ggtaaaagaa ttgggggcat tgattgccaa cgcgctgagt agtgaagatg
    41821 attatttatt attggatgtt aattgctatg ttcaagtagg tagttctcaa gaagtttacc
    41881 ccagtgaaga gttggtgcta gacaaaagtt cgtcagataa gaaaggaaag aaaaccaaaa
    41941 ttttgtatgc agtaaatgat attgctgcca tgcactcaca aaaaataggt aatgccattc
    42001 gcaccatcga tacatggtac ccggatttta caaatcaaga gcaaactgca ggtccgatag
    42061 ctattgaacc ttatggagcc gtaactaacc taggtagggc ttatcgcacg ccaaaagaca
    42121 aacaagactt ttataccttt tttgatgcgt gggcgcgagg cgagcagctt gcaaggatag
    42181 aagatgaaca ctatgttatg gccgtgttag ttcgtggtgg tgtttttggc aaaagtgata
    42241 agaaagaaag tgataagtag gtgattttat gaattactat tttgatatta atttgttatc
    42301 ggatgccgaa atcccaagta ctgtgctaat aaatgccgtt tgcaaaaaac tgcataaatt
    42361 actttgcgat ttggattcaa cccggattgg tattagtttt ccaaaataca agattacatt
    42421 gggaaatgtt ctgagactgc acggtactga atttgatttg caaaagctgc atgaagtaag
    42481 ctggcttggt ggcatgaacg gttattgtaa gattagtgaa gttgctactg tgccagtcaa
    42541 tacaaagcac cgaacagttt atcgtaaaca gcctactatg agtcagtcca aactcaagcg
    42601 gttattaaag cgcggcacga ttacgaacga tgaggtgaaa tcctataaag caaaaatggt
    42661 tgctgaaaaa gggttgaata atccgtatct ggatttagtt agtggtacta attgccaacg
    42721 acaccgacgt tatattgttt taggtgaact gctggatgag cctgtagagg gtgggtttga
    42781 tcaatttggt ctttccaaaa cagtcacggt tccttggttt gattgaagga aaattgtatt
    42841 ggtgatacca aaatattgaa tgaattttgc ggagaaaagg agggctctat tttcttttta
    42901 tcaccaataa ttttagctct ttaaaaatta aatttataat caagaagtta tttcttatat
    42961 aaaacacatt gggtaaaata atcattttta gttaactgct tataattatt ggttattttt
    43021 gtgaatgttt tggttcactg ccgcacaggc agcttagaaa gtttggatgt tagcggaggc
    43081 gttgcaagag ttacagcagt taggaggatg gtcaagtttc agtatggttt tacgttacgc
    43141 acacctctca agtcatcgcc ttcgagaggc agctaagcgt atttacgtga caaaatccct
    43201 acacgccgag tcagtgaaat atttttaatc aaccagtctt atgcaaggca atgattttta
    43261 atgatttact gatgccggtg cgcagactcg aactgcggac ctactgatta cgaatcagtt
    43321 gctctaccac ctgagctaca ccggccgacg tgacgcttat gatcacgtaa gcggggcagg
    43381 aggtcaagtt ggcgggtacc gcaatcatca aaaccctgta ttgcaacttc attccccttc
    43441 gcctataaag gcatctcgtt tttggggaag ttattatgca gagaaatcga acggcgggat
    43501 tcacattaat ggaattatta atcgtgattg ctatcattgg tattttgatt ataatcgcga
    43561 ttccttctta tcatacctac actcggcggg ctcattttac ggaagtcgtc caagccacgg
    43621 cgccctacaa actaggggtc aaagagtgtt accaaatgac aaacgacctt tcagaatgct
    43681 cagcggggga taatggcgtg ccccctgcta tagcgtcggg gagcgggaca ggattggtcg
    43741 atgccatcga aattcaaaat ggcgtaatca cagtcacacc tcaagtaaaa tatgggattg
    43801 aagcgaaaga caattacatc ttaacgccga cccctgaacg cgaagggttg acttgggcct
    43861 ccagcggcgg aggcgtggcg gctggttatg caaactaagg tcgagggcct cgctcatatt
    43921 ttattgcaga caaatgcgtt aactaacagc caaattgccc gtgctattga acaggcggcg
    43981 ggagcacaat caccgttgct gcattattta gttaccgaga aaatagtatc ctcagaaaaa
    44041 atagcagaag cctgcgccac ttactttggt ttagaagcga ttaacttgca gactcaacca
    44101 ctgaacccat cgctttgtca tgaaatacca cggaaatatt taatgcgcta tgcgttcatt
    44161 ccacttgcag taaaatcacc tacgctagct attagcgatc cgctatattt tcccttaatc
    44221 gaagagctcc agtttcagac taataaacaa tacaaaattg tttttgctcc ctataaatca
    44281 tttgctgcgt taataaataa ttttgtgagt cgtcaaattt acgagacagt ttcacaaggt
    44341 aaagcttcca ttgttgagtt agtaaatcaa gtgctcacgg atgccatcta tcgagaagcg
    44401 tcagatgttc actttgaacc gatgcaacaa cattaccgaa ttcggatgcg tatcgatggg
    44461 attttacata ctactactct cttgccaaat acacagtcgc cagcaatgag tagccggtta
    44521 aaagtactgg ctgaattaga tatttctgaa aaacgcttgc cgcaggatgg gcgcttttat
    44581 tttacaacgc ttacccatct taaacgtgac tgccgactta gtagctgccc gactttattc
    44641 ggggaaaaaa tcgtcatccg tttactaaac cccgttcatc atttattaaa atttgaagag
    44701 ttgggtttag aagaaaaacc gaagcaactc atcatgaaaa aaatcaaaca accccaaggt
    44761 ttgattcttg tcacaggacc cacgagaagc gggaaaacgg tttcactgta tgccgcgctt
    44821 aatcagatta attcaactca aaaaaatatc tccaccgtag aagatcccat tgaaatacaa
    44881 ttagccgggg ttacccaagt taatattcgc ccaaaagccg gacttaattt cgccgctgta
    44941 ttacgcgctt ttttgcgcca agatcctgat gttatcatgg tgggggaaat tcgcgatttt
    45001 gaaactgctt ccattgctgt tcgcgctgca cataccgggc atttagtctt atccacctta
    45061 cataccaata gcgccgtcga atgcattaca cgattaatcg atatggggat cgagccattc
    45121 aaccttgcta gcgtattaaa gctcgtggtt gctcagcgac tcgtcagaca gctttgcgct
    45181 cattgccaag caacgaagat ttcctgcccc ttttgtttaa acggatacca ggggcgtacg
    45241 ggaatctatg aagttctgcc tattactcct tccattatcg aacttatttt acaaaaacga
    45301 tccgcgcaag aaattaatgc ctgcgccata caagagggca tgcaaacttt gtggcaagca
    45361 gctttgaata aagcaaagac gggtattaca aacctcaacg aaatttaccg cgtgattcaa
    45421 tctgaaaata actatgctta aatactggaa aaataggata agatcaaaaa atattttggg
    45481 ccttttccgt caattaaatg tattaataaa tgctgaaatc ccactcgctc aagcacttgc
    45541 tttattggcg ggaggatctc attcaggctc attgcgccag ttaatcttag ccatttggag
    45601 caaaatcgaa aacggtctga gtctttctga gacgttaaaa atttaccccc gctatttcca
    45661 taccgttcac catgaaataa ttcatgccgg tgagcaaagt gggaagctcg gcgaattatt
    45721 aaaattatta attcattatg aagaaggttt gtttattttt aagaaaaaaa ttcaaaaagc
    45781 aatccgctac cccttaaccg ttctttcaat tgccctaggc gttaccattg gtttgttgga
    45841 gttcgtcatc ccgcaattcc aaaatgcttt ttctgaattt ggttcacaac tgcctttctt
    45901 cactcaagtc atcatcaatc tcgcccacaa cgtacgcgct tatggcctac ttattttttt
    45961 tagcttttct ctttttctat tcgtttttgt gtacgcaaaa aaacattcag acaaattctc
    46021 caagtccgtt gatcacgcat taataaaaat tccactcatt ggaaagggta ttcaaaatac
    46081 aatgataacc ctttggataa aagtgctagc gaccctgagc gcggcaggta tccctttgaa
    46141 caaagcgtta atcactgcca atcatatcat tcgtaaccac gctttaagac aagccctcga
    46201 caaactgcct tgttggatta gcgaaggcgt ctcctttagc accgccattg aacgctgcgg
    46261 ctttttttcc caccaagcaa tccagcttat tcacatcggt gaaaattccg gaacactcaa
    46321 cgaaatgttg aataaagtgg ccgttattta tcaggaagaa atagacgagc gttacgatcg
    46381 tctcagcgag tgcctggaac cagctatcat gatagtattg gcattattaa tcggcggact
    46441 aattatcgct atgtatttac ccgtattccg aattggttcc gctctttagc agcgatttca
    46501 agtgaaaaac agaaatgcag attatttctt ttttacaatt tcatttttat ataacgatcg
    46561 ttgcaatcgc cgttatcgga ttgatcgtgg gcagttttct taacgtggtt atcgtccgtt
    46621 atcctacctt gctcgccgca cgttggcgcc gagagtgtca ggaatacctt aatttacctg
    46681 tcgaacccaa accaaaattt aatttagcaa ctccgcgctc ccagtgcccc cgatgcaaaa
    46741 aaactctaaa aattctccat aacctgccat taataagcta cttaaccttg cgcggtcgct
    46801 gcgcatattg tcatgaaaaa atatcgccgc tttatcccat agttgaatta ctctgcgcca
    46861 ttttatcggt ggctattgtg attcgttatc agataagctg gcaagcgctg gctggattac
    46921 tacttacctg ggtattaatt gtgctttttt ttattgattt aaaaacgcaa ctcttgcccg
    46981 acgcgatcac acttcctact ttatggtttg gtctttccct cagcctcttt tatatgttcg
    47041 tatcacctta tcaagcaata tttggcgcta tactcggtta cggacttcta tggattaccg
    47101 ccgcgtttta tcaattaatt cgtaaaaaag aaggaatggg ccgtggcgat tttaaaatgg
    47161 tcagtatgtt gggcgcttgg ttcggccctg gcattgtatt aaatgtttta ttgctggcgg
    47221 tttttctcgg cctgataaca agcttcatgc tactagccct gaaaaaaata tcagtgaaac
    47281 aacccattcc ctttggccct tttattgctg tagcgggctg gatcagcctt ttgtcgggtc
    47341 cggttctaat acacaaattg atttcttatt tataaaggag gtgctatgtt acggattgga
    47401 ttaactggtg gcatcggaag cgggaaaagc accgttgcca actactttgc agaattaggc
    47461 gctcctgtca tcgacgctga tcaaatcgct catgaaataa cgaaacctga tcaagcggcg
    47521 tttaaacaaa taatcaatca ttttgggagt gcagtgctta ctaagggaaa atttttaaat
    47581 cgcactaaat tacgagaact aatttttgaa aatcctgacg atcgacaatg gcttgagaat
    47641 ttattacacc cccttatcat tgcgaaaatg aaaacccaac taaaaaaaat aaaagcgcct
    47701 tattgtattt tagcgatccc tttacttgcc gaggcctcgc agtcggtcga ttttatcgac
    47761 cgaatcttgg tggtggatgc gccagaaacg ctgcaaatac aacgtacaaa atcgcgcgat
    47821 caactttcgg atcaacaaat tcaacttatc ctacaatcac agagcccgcg tgaaaaacgg
    47881 ctcgctatcg ccgatgacgt gattgttaac gatcagacga tccccatttt gcgcaaagcg
    47941 gtttttcagc tacactgtaa gtatttgcaa atcgcacaaa cataaaaaac acataaggct
    48001 aaccaatgag cactttacga gtcttacacg aaaaatccga acttgggaaa acaacggttt
    48061 accctaagga atacgcccct catttgttat tgcctatccc aagggactta aatcgaaaaa
    48121 cactcaacgt caacgtcagt gagccaccac ctttttacgg ctatgactta tggaatgctt
    48181 acgagctgtc ttggttaaat gaaaaaggga aaccttttgc cgccaggggt gaatttataa
    48241 ttccggccac ttcatcccat ttaatcgaat ctaaatcatt taaactgtat ttgaattcct
    48301 ttaacaacga acgttttgcc gacgcagccg ccgtttcgca aaccatgaaa cgcgatctta
    48361 gcaaacgcgt caacgagtct gtcacggtta atttcatcct gcacgaaacc gagatacccg
    48421 tggcctattc tccaaagggt agccttttgg atgttttag
//
