LOCUS       NC_009328              26413 bp    DNA     circular CON 07-FEB-2024
DEFINITION  Geobacillus thermodenitrificans NG80-2, complete sequence.
ACCESSION   NC_009328
VERSION     NC_009328.1
KEYWORDS    RefSeq.
SOURCE      Geobacillus thermodenitrificans NG80-2
  ORGANISM  Geobacillus thermodenitrificans NG80-2
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus.
REFERENCE   1  (bases 1 to 3550319)
  AUTHORS   Feng,L., Wang,W., Cheng,J., Ren,Y., Zhao,G., Gao,C., Tang,Y.,
            Liu,X., Han,W., Peng,X., Liu,R. and Wang,L.
  TITLE     Genome and proteome of long-chain alkane degrading Geobacillus
            thermodenitrificans NG80-2 isolated from a deep-subsurface oil
            reservoir
  JOURNAL   Proc Natl Acad Sci U S A 104 (13), 5602-5607 (2007)
   PUBMED   17372208
REFERENCE   2  (bases 1 to 3550319)
  AUTHORS   Wang,L., Feng,L., Wang,W., Cheng,J., Ren,Y., Zhao,G. and Gao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2007) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, Hongda Street, TEDA, Tianjin
            300457, The People's Republic of China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/07/2024 01:12:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,672
            CDSs (total)                      :: 3,549
            Genes (coding)                    :: 3,461
            CDSs (with protein)               :: 3,461
            Genes (RNA)                       :: 123
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 50 of 88
            Pseudo Genes (incomplete)         :: 56 of 88
            Pseudo Genes (internal stop)      :: 20 of 88
            Pseudo Genes (multiple problems)  :: 30 of 88
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:38:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 289767
            Orig. end                         :: 316180
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000557.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26413
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26413
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26413
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16413](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16413
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(540..2015)
                     /locus_tag="GTNG_RS01555"
                     /old_locus_tag="GTNG_0259"
     CDS             complement(540..2015)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013144145.1"
                     /locus_tag="GTNG_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0259"
                     /product="flavin monoamine oxidase family protein"
                     /protein_id="WP_081432631.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-07, bitscore:
                     28.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHPYISPRLPMETMISIIRNGLKKTSIPKKIVVIGAGMAGLVAA
                     SLLKQAGHRVTILEASERVGGRIYTIRSDFRDDQYFEAGAMRIPHTHRLTLEYIQKFNL
                     PIHPFVNSTPRDILYFRGIKARLSEYERHPDLFGFPIASYERGKTASELLQMAVRPVIQ
                     FIEQNPEKHWPIVIEQLDRYSFDTYLRYNPFGLRLSVGAIDMIKAVLSLEGFPELSFLG
                     LLRELMTLFTPNMRFYKIVGGNDRLPKAFLPQLKDELLFSHKVQKIVQNKNSVTIHAIH
                     TKILQPFQITADRVIVTIPFSILQFVDIEPRHSFSENKRKAIRELHYVGSTKTGIQFKT
                     RFWEKEGLFGGRTVSDLPIRYTQYPSQGIGTTGPGVVLASYTWEDDTIPWDSLSAEERL
                     EYTLKNLAVLYGEQVYREFETGTSHSWVRYPYSGGAFTLMKPNQITEISPYIATPEGRV
                     HFAGEHTSTHHGWIQGAIESGICAAYEVNNSPA"
     gene            complement(2112..2885)
                     /locus_tag="GTNG_RS01560"
                     /old_locus_tag="GTNG_0260"
     CDS             complement(2112..2885)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886695.1"
                     /locus_tag="GTNG_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0260"
                     /product="VOC family protein"
                     /protein_id="WP_011886695.1"
                     /transl_table=11
                     /translation="MNIAFDHLVHLTERPEQAKAAFEQLGFTASHGGRHLSWGTYNALC
                     YFKPLCYIEWIGIADMQTANTCGNPLITLLVADSQEGSGFSQLAFRTNDIESLTKQLRN
                     KGFTPIGPFPGSRQRDDGKLLTWSMLFLEDDTGGAFRYPFFIEWGDSDDMRMNELAPLM
                     RHPIGSPSLSSISLYTLDLDRAIDGYRRLFGLPVPEVRHDEEGTYAELTVGGIALRFYK
                     ADDRPSTRPFLCRIAGIQPRRRFELAGGTYIVSES"
     misc_feature    complement(2857..2872)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            3265..3708
                     /locus_tag="GTNG_RS01565"
     CDS             3265..3708
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GTNG_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_041264180.1"
                     /transl_table=11
                     /translation="MHQLQEHRFPLGDEERAETMLCHSFPQREANLGVDAVIIPSGSLV
                     VSHAFLTVPAEWRFIAARVVFVDKLTQWDIHRVRAVERLGKRCFVHRYKFLFISYGVYV
                     RVCPLTTTQIGPECCFISLNFGIIIVLWKVDHVGGEYDVANFD"
     misc_feature    complement(3287..3302)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.16"
                     /tool="antismash"
     gene            3689..3979
                     /gene="gatC"
                     /locus_tag="GTNG_RS01570"
                     /old_locus_tag="GTNG_0261"
     CDS             3689..3979
                     /GO_component="GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA]"
                     /GO_function="GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gatC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229790.1"
                     /locus_tag="GTNG_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0261"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="WP_008881445.1"
                     /transl_table=11
                     /translation="MSRISIEQVKHVADLARLAMTDEEAELFTKQLDAIITFAEQLNEL
                     DTENVPPTSHVLDMRNVMREDEPEPGLPREEVLKNAPDQQDGQFRVPAILE"
     gene            3992..5449
                     /gene="gatA"
                     /locus_tag="GTNG_RS01575"
                     /old_locus_tag="GTNG_0262"
     CDS             3992..5449
                     /GO_component="GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA]"
                     /GO_function="GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gatA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388550.1"
                     /locus_tag="GTNG_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0262"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="WP_008881444.1"
                     /transl_table=11
                     /translation="MSLFDHTVSELHTLLQKKEVSISDLVDESYRRIGEVEEKVQAFLT
                     LNEEQARAKAKELDDKLAKGEETNPLFGLPIGIKDNIVTKGLRTTCASKILYNFDPIYD
                     ATVMERLNAAGAITIGKLNMDEFAMGSSTENSGFQLTRNPWDLERVPGGSSGGSAAAVA
                     AGEVPFSLGSDTGGSIRQPAAFCGVVGLKPTYGRVSRFGLVAFASSLDQIGPITRTVED
                     NAYLLQVIAGVDPMDSTSANIDVPNYVEALTGDIKGLKIAVPKEYLGEGVAEEVRQSVL
                     AALSVLEKLGATWEEVSLPHSKYALATYYLLASSEASANLARFDGVRYGYRTDNAKNLI
                     DMYKQTRSEGFGSEVKRRIMLGTFALSSGYYDAYYKKAQKVRTLIKRDFENVFEQYDVI
                     IGPTTPTPAFKIGEKTSDPLTMYMNDILTIPVNLAGVPAISVPCGFVDGLPVGLQIIGK
                     HFDESTVYRVAHAFEQATDYHKQKPVL"
     gene            5463..6893
                     /gene="gatB"
                     /locus_tag="GTNG_RS01580"
                     /old_locus_tag="GTNG_0263"
     CDS             5463..6893
                     /EC_number="6.3.5.-"
                     /GO_function="GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /gene="gatB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388551.2"
                     /locus_tag="GTNG_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0263"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="WP_008881443.1"
                     /transl_table=11
                     /translation="MNFETVIGLEVHVELKTKSKIFSSSPNAFGAPPNTQTNVIDLGYP
                     GVLPVLNRQAVEFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQYDQPLGKNGW
                     IEIEVNGKKKKIGITRIHLEEDAGKLMHTGDGYSLVDFNRQGTPLIEIVSEPDIRSPEE
                     AYAYLEKLKAIIQYTGVSDCKMEEGSLRCDANISLRPLGSDKFGTKTELKNLNSFNFVR
                     MGLEYEAKRQEKILLSGGVIRQETRRFDEATKTTVLMRVKEGSEDYRYFPEPDLVMLYI
                     DDEWKERVRASIPELPDARRKRYVEEWGLPEYDAKVLTLTKEMADFFEATVANGADPKL
                     ASNWLMVEVSGYLNSEQKELHDIALTPESLAGMIKLIQNGTISSKIAKKVFKELVEHGG
                     DPEKIVKEKGLVQISDEGALRKIVLEVLDANPQSVEDYKNGKDRALGFLVGQVMKATKG
                     QANPPLVNKLLVEEINKR"
     misc_feature    complement(6953..6962)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    6992..7005
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.04"
                     /tool="antismash"
     gene            7080..8384
                     /locus_tag="GTNG_RS01585"
                     /old_locus_tag="GTNG_0264"
     CDS             7080..8384
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (89-224). E-value: 5.4e-11.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_GTNG_RS01585_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013522839.1"
                     /locus_tag="GTNG_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0264"
                     /product="homocysteine synthase"
                     /protein_id="WP_008881442.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1e-14, bitscore:
                     52.3, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.8e-09, bitscore:
                     32.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-07, bitscore:
                     28.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEERAFRPETLAIHAGQQPDAETGSRAVPIYQTSSYVFRDSEHA
                     ANLFGLKEEGYIYTRIMNPTNDVLEKRIAALEGGVGALALSSGQAAVFYSLINIASAGD
                     EIVSSSSIYGGTYNLFAHTLRKFGITVKFVDSSDPENFEKAITGKTKAVFAETIGNPKN
                     DVLDIEAVADIAHRHGIPLIVDNTVASPYLLRPIEFGADIVVHSATKFIGGHGNSIGGV
                     IVDSGKFDWKGSGKFPEFTEPDPSYHGLVYVDAVGEAAYITKARIQLLRDLGAALSPFN
                     AFLLLQGLETLHLRMQRHSENALAVAKFLEEEEAVESVSYPGLPSHPSHELAKKYLPNG
                     QGAIVTFEIKGGVEAGKKLIDSVKLFSHLANIGDSKSLIIHPASTTHEQLTPEEQLSAG
                     VTPGLVRLSVGTESIDDILEDLRQAIRQSQTVAVK"
     aSDomain        7347..7751
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GTNG_RS01585_Aminotran_5.1"
                     /evalue="5.40E-11"
                     /label="GTNG_RS01585_Aminotran_5.1"
                     /locus_tag="GTNG_RS01585"
                     /protein_end="224"
                     /protein_start="89"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AAVFYSLINIASAGDEIVSSSSIYGGTYNLFAHTLRKFGITVKFV
                     DSSDPENFEKAITGKTKAVFAETIGNPKNDVLDIEAVADIAHRHGIPLIVDNTVASPYL
                     LRPIEFGADIVVHSATKFIGGHGNSIGGVIV"
     gene            9056..9226
                     /locus_tag="GTNG_RS18005"
                     /old_locus_tag="GTNG_0265"
     CDS             9056..9226
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="GTNG_RS18005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0265"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_008881441.1"
                     /sec_met_domain="TIGR03731 (E-value: 1e-20, bitscore: 71.1,
                     seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 8.4e-06, bitscore:
                     22.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDIVVKKQDDVVQPNVTSKSLCTPGCITGVLMCLTQN
                     SCVSCNSCIRC"
     CDS_motif       9056..9124
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKFDDFDLDIVVKKQDDVVQPN"
                     /locus_tag="GTNG_RS18005_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9125..9226
                     /prepeptide="core"
                     /locus_tag="GTNG_RS18005_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="17.80"
                     /molecular_weight="3263.9"
                     /monoisotopic_mass="3261.5"
                     /core_sequence="VTSKSLCTPGCITGVLMCLTQNSCVSCNSCIRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDIVVKKQDDVVQPN"
                     /leader_location="[9055:9124](+)"
                     /alternative_weights="3281.9"
                     /alternative_weights="3300.0"
     misc_feature    complement(9644..9655)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            10001..13141
                     /locus_tag="GTNG_RS01590"
                     /old_locus_tag="GTNG_0266"
     CDS             10001..13141
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014194788.1"
                     /locus_tag="GTNG_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0266"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_011886696.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.2e-149,
                     bitscore: 497.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.5e-17,
                     bitscore: 61.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.1e-35, bitscore:
                     121.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDLVFKNIDTFMIRTPVLSVDNYLRFFDQKLTEGEMKERLLEIC
                     HNPVFRESILVASKSLYNKMIDFCNGKEIKKYDYFIKAIYKYLIRISTRPTPFGLFAGV
                     DFGEYTDENTSIRYGTNKYKKFARPDLEWLMKIIKKLEQEQYEQLWFTVNDSIFLKGER
                     AYLLHSTRKDDDKRVNEISVRVTLPFKITCELARHLIHYQTLKKELIKQFPNTSEEKIE
                     RFLKQLIENEFLISNLRPPLTVMDQLDYLIKRLKESHIEEWSNELIDIQQKIRTYTMTP
                     LGEGEQIYKELHKKMKKLADTKNVLQVDMKLNLQEKKLNKQVIKDVNELMHILLPFSMT
                     YQQTDSPLSRYKQEFIEKYGVDREVPLLEMLDNDLGIGAPMDYTNPKNARLAVGVPHQL
                     IDEQLREYFLHKYIEAVKDKKSITITEDEIKELGLDDYDYQSIPDSLDINVIVKCDSEQ
                     DLENNHFKYYIGPNLGSTHAGKSFGRFSYMMEGEEKLFETLNKEMLNLNNDSGEYVTCE
                     LVYLPNETRHANVTRNIHNSEYELALFTNNSKDEYHRLSLNDILIGIENDMFYAKSKTL
                     NKKLIITMNNMLNTQNAPNAIRFLYDISLDGKKIWCNFPWDTIFQDYAYIPAIEYKNFV
                     IAPRKWVINKIIKTNDKISFTEFEKRFKKFCSDYDVPKYVYLTFADNRILLNTEDENCL
                     RILHHEFNNRYGNIILSSYEEADLHLVKDDDEKEYVCELVIPLVKVKQENRQWYAKAKK
                     SNHIPSFSDIRVKLPFENWLYLKLYGVHSRADDFIAFYLSEYCREKLAKGEIEKYFFIR
                     YADPEQHIRLRLNASEEKLLQIYPDMKQWLRTLIEKRVVSRFSIDCYEREIERYGGTEL
                     IDLAENLFFFDSIVVEDILKLKRLKHIQFSDEVIGMVSIIHYMEQFGLNYESQLDFLQQ
                     QVNKQDYREDFQKNRSVYMKVCNTDNDWQGLRDTDEGMLLLNVLNQRNRSIKEYASKIQ
                     DGLEASSELSILDSVVHLHCNRLFGIDREFEKKIRTLVAHTLYALKYIKAHGLVLKN"
     aSDomain        10457..10723
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GTNG_RS01590_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="2.00E-19"
                     /identifier="RREFam001.1"
                     /label="GTNG_RS01590"
                     /locus_tag="GTNG_RS01590"
                     /protein_end="241"
                     /protein_start="152"
                     /score="61.0"
                     /tool="antismash"
                     /translation="VNDSIFLKGERAYLLHSTRKDDDKRVNEISVRVTLPFKITCELAR
                     HLIHYQTLKKELIKQFPNTSEEKIERFLKQLIENEFLISNLRPP"
     misc_feature    13204..13217
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.09"
                     /tool="antismash"
     gene            13308..15137
                     /locus_tag="GTNG_RS01595"
                     /old_locus_tag="GTNG_0267"
     CDS             13308..15137
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229812.1"
                     /locus_tag="GTNG_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0267"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_008881438.1"
                     /transl_table=11
                     /translation="MNIKEYDDHVTIKDIVKSIRIVPKTLVLIKNVDKQSFFIIIFLSL
                     LMGGAPIVTLLGSQNLLNAIGSQNIHIIISALIFYISAVLLSEIISSFMEYYQNKFQTL
                     INYKLNLQIMDKCTRLSLRHFEDAEVYDMLQRVQNETPYKPFEVFLSILGAISAIVTFF
                     SSMMILIHWKPWVLIILIFIPLVFSFYFFKIGQREFNVSWLRAPEKRKSWYLSYLMTRD
                     NTFKEVKIYNLAGYILNKFKEINKTFVGQDIHLFKRRTVFTFIFELVEQICINTVLVII
                     IISALAGEILIGHVVGLIQALNLISSNSKKILNIIHSLYKNNLYINQLFEFLGLDEEVL
                     DKGDRFVSGIDKIENIKIRNLTFRYPTNPKVVLKNINLDINKGERIAIVGANGSGKSTL
                     IKLLLKLYEHDEDSIFYNGVSINDLDTEQLRKNIAVLFQDFVKYELKLRENVGFGDITR
                     IDRDGELKQAMERARVNFIEDLDTQLGLWFVDGVQLSGGQWQKVAIARALFRDASVYIL
                     DEPSSALDPISEKEVIDMFINMTKDKIGIFISHRLSTAKLADKIVVMNDGEIVGIGTHW
                     ELLATNELYRRMYELEALKNEEEYEHLNESAGL"
     gene            15118..16413
                     /locus_tag="GTNG_RS01600"
                     /old_locus_tag="GTNG_0268"
     CDS             15118..16413
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014194793.1"
                     /locus_tag="GTNG_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0268"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_230459250.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-86, bitscore:
                     288.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVCNLAKKLSDYENMKRIVNHPSNYIKIGNKTINPFNELSLS
                     HGLPALCALYGELSEQYPDEGWDLLGHQYMKKIGEQMNQHGFPSLSMFTGLAGIGLAAV
                     CLSKGGKRYQNFISTINQVIEERIGEMIEYLKQKPYPNMDDYDAISGVAGIASYCLLFP
                     QEMKKSITLILKYIIDLSQDKQMEDINVPGWYIPPMNAFSDTERRKWPSGFFNIGLSHG
                     IPALLIVLCNAKKLNIYVHGQDECIQRIADFLMKFQIKDENGSYWGTHVSLEEYKNGSV
                     LNKDTRDAWCYGTPGVAYSLLIAGKTLNNQSYIDCAVSGMKLASKRLYNIFSPSFCHGL
                     SGVAYICNRFYEETNISDFKEAACKLVDDIIKFYNEEFPFGFKNIEESEGSTKYYDYVG
                     LIDGTAGILLTILAIQNSKKTPWDCAFLLSEV"
     misc_feature    16620..16633
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.41"
                     /tool="antismash"
     gene            16756..17454
                     /locus_tag="GTNG_RS01605"
                     /old_locus_tag="GTNG_0269"
     CDS             16756..17454
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881436.1"
                     /locus_tag="GTNG_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0269"
                     /product="response regulator transcription factor"
                     /protein_id="WP_008881436.1"
                     /transl_table=11
                     /translation="MNNKKILVVDDDEDICCTIKQYLELHHYQVETVHSGVEALKMIND
                     DFDLIVLDIMMEGIDGMELCTIIRDRVDYPIVFVSAKTLEEDKVQALAIGGDDYITKPF
                     SLKELKARIDSHLRREERIRSNERYLLSSKNITIDLLANEVFCKGKKLPLTKKEYEIVK
                     LLMLNKKVVFSKERIFERVWGIDSDSQLDTVTESIKNIRKKIKAVDPETSYIQTLYGLG
                     YKWDVTDEKE"
     gene            17441..18859
                     /locus_tag="GTNG_RS01610"
                     /old_locus_tag="GTNG_0270"
     CDS             17441..18859
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888809.1"
                     /locus_tag="GTNG_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0270"
                     /product="ATP-binding protein"
                     /protein_id="WP_011886698.1"
                     /transl_table=11
                     /translation="MKKNKTIKRDFYLLVVKVVLATAISSAVTYLCLIYLIITLATNDV
                     VKPTNYFVKDLDLIEKKVKENEEAIFKGRLIPIHRYSEKIQGEVVDISGKHLYGDREII
                     DDQVDISQSINREIVKGSYVYRFIPLKHDNAIQAVYVLKAPFGFIINNQNRFEAVLIYA
                     VMFISPLIFFIVYLIFFTSRLYKSLFHNVKLLLQASDHIASGNFDFQVSGLKRKEFIKI
                     QDSFNTMISALKEMVERLAKTDDERKMMVSSIAHDIRTPLTVIQGQIDLIQDLRKLDHF
                     DVTPHLEIIRKNCGKMTMLTDNLSLLYKVENDHFSLNGKEVDVRQILEEKKLEISTMVY
                     HQKSINICFDVNLQKSRYILDEAMLMRVLDNILYNSLRFTKSGEIKLEVYDEKEGNECK
                     IYFRCSDTGTGFKENDTSLLFQPFYQDKQYKNHVGLGLYIAKRIVNHHGGEIWAYNNEK
                     GGATVEFYIKELSD"
     gene            complement(18953..19387)
                     /locus_tag="GTNG_RS01615"
                     /old_locus_tag="GTNG_0271"
     CDS             complement(18953..19387)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881434.1"
                     /locus_tag="GTNG_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0271"
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="WP_011886699.1"
                     /transl_table=11
                     /translation="MKNSILLLMLIGILFIGGCSLVSDLKKTATQNMEIDRKLPKYELN
                     KENLQEIHYQGRTYMIQAAKVDRNQLNKPIGKVAETITINEHHQILSKKELRKIEVIPD
                     QTDEKRTHLNFGWVYSIKGVNPDEEVAVTVNHQFLIAKRK"
     gene            complement(19442..20230)
                     /locus_tag="GTNG_RS01620"
                     /old_locus_tag="GTNG_0272"
     CDS             complement(19442..20230)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888811.1"
                     /locus_tag="GTNG_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0272"
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="WP_041264183.1"
                     /transl_table=11
                     /translation="MWFLRLLSSEWIKTKRTAIRMMVIITPIIYSLFMVWYFSHYRTST
                     FWQMKIYQGFFEVMAVSLPIIISLLTGLMSYQEEKAGSFMNILTGPVSKVQWYVGKLTL
                     LIFIACADILLATILMLFGMKYVLKVAHIHYQLFLQGAMLSIVGSLILFSLHLFISFAF
                     GMGASIAVGSGGFLISALIGATSLGDHVWSYIPWAWAVRLSQFPILMMPEVKQALGAQL
                     LNSFSLSLWEGIAYALLSFIIVTIIGSIWFHRWEGNQPHE"
     misc_feature    20212..20221
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.78"
                     /tool="antismash"
     gene            complement(20232..20978)
                     /locus_tag="GTNG_RS01625"
                     /old_locus_tag="GTNG_0273"
     CDS             complement(20232..20978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886701.1"
                     /locus_tag="GTNG_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0273"
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="WP_011886701.1"
                     /transl_table=11
                     /translation="MLNMFESERLKYKRTFAKKLVFIAPLFFVLYAIITMPTVNSTHNY
                     FEYAVFNWWPLIFVPIGTALIASLSTVREKKSGNDKVLRCHDISIVRLWWSKITVIAYY
                     MLLSTIELIILLVLLKWLFPNSLSSATVAVFASLVIWLTSLAYIPIGLFVAERFGMVVS
                     IIVSVIGLALGVVMAAQPYWLFIPWSWGMRMMCPIVGVHPNGVPLEKGSPLLDPSVIPI
                     GLAIALVMFLLLSFLTAVWFARKEVY"
     misc_feature    complement(20972..20986)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            complement(20997..21686)
                     /locus_tag="GTNG_RS01630"
                     /old_locus_tag="GTNG_0274"
     CDS             complement(20997..21686)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888813.1"
                     /locus_tag="GTNG_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0274"
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_011886702.1"
                     /transl_table=11
                     /translation="MGEYMLETHHVSKAFGKQLVVDDVSIKVKKQTVYGLLGPNGAGKS
                     TLLKMLTGLLRPTKGEIMINGHPWSRKDLKDIGVLIESPALYGNLTAHENLLVHAKLLH
                     LPESRIQEVLNIVGLENTGKKKASQFSLGMKQRLGIAKALLNHPKLIILDEPTNGLDPL
                     GIQDLRKLIQSFTENGITVILSSHILSEVKQLADYIGIIQNGKLRYEGKIDESQDLEKL
                     FVDVVNE"
     misc_feature    21804..21817
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.18"
                     /tool="antismash"
     gene            complement(22341..22970)
                     /locus_tag="GTNG_RS01635"
                     /old_locus_tag="GTNG_0275"
     CDS             complement(22341..22970)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881429.1"
                     /locus_tag="GTNG_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0275"
                     /product="ABC transporter permease"
                     /protein_id="WP_011886703.1"
                     /transl_table=11
                     /translation="MELLQTFIERQEEIWIAFQEHVLLSAIAMGIAIAVAVPLGVVLTR
                     YRKLAEPIIGIAAIIQTIPSLALLGFMLPIFGIGKLPAIIALTLYALLPILRNTYTGIL
                     GVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGL
                     GDLIDRGLRIADKNLILAGAIPAAILAIVFDWLLRKVEKKVTPKGL"
     misc_feature    complement(23041..23056)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     gene            complement(23360..24493)
                     /locus_tag="GTNG_RS01640"
                     /old_locus_tag="GTNG_0276"
     CDS             complement(23360..24493)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229819.1"
                     /locus_tag="GTNG_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0276"
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_011886704.1"
                     /transl_table=11
                     /translation="MIRFENVTKQYEDGFVALKNINLEIRKGELVALIGPSGCGKTTTM
                     RMINRLIEPTSGKVYIDGQDISELDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLK
                     KWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEP
                     FSALDPISREQLQDDIIRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPD
                     QMLRRPANSFVREFIGEDRLQMRTRQTAVPTAEDLMSDDVATISPRRGLAEAFRLMKAR
                     KVDSLVVVDKKRSFLGIVTLKQIEQRYNEEHLLVADIADYDVTTLQKEAGVTDVAALFQ
                     DSDVRIIPVLDGDRLVGGITRSSMMRALAEWTFQQHA"
     gene            complement(24510..25412)
                     /locus_tag="GTNG_RS01645"
                     /old_locus_tag="GTNG_0277"
     CDS             complement(24510..25412)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020756897.1"
                     /locus_tag="GTNG_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GTNG_0277"
                     /product="glycine betaine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_008881427.1"
                     /transl_table=11
                     /translation="MLRKWFMSLLAVGLVLGLAACSGKSDAKGKIVITGKKFTEQMILT
                     HVLAEYVKANTDLDVEVKESLGGAFMLQQAIENGDIDMYVEYTGTGYLNILKQPYDPTK
                     TPEQIYNETKKLYKEKYNIAWLKSLGFNNTYALAMRRDLAEKLGVKTYSDLVNHSSSLT
                     FGSDAEFFERSDGYDGLVDTYGFHFKKTVNIDPDLQYEAAKNGKIDVITAYTTDARIKK
                     YDLVVLKDDKQYFPPYYAVPIIRQEVLDANPGLEEKLNQLANILTDEKMMELNGEVNLE
                     GKQPRKVAIDFLKSEGLID"
     gene            25665..25844
                     /locus_tag="GTNG_RS18555"
     CDS             25665..25844
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GTNG_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148206523.1"
                     /transl_table=11
                     /translation="MTPMLPPPRQFTGLPSGLAKLAFVIAESLQPMAKKMKQRQTAGGQ
                     EVALGRLLFGCFET"
ORIGIN
        1 aaatataaag aagcagcgca ggagcttggg atgtttttag ctcgccgcgg cattacgctg
       61 atttacggcg gaggaaaggc tgggctgatg ggagaggtgg ccgaggcagt gctaggccat
      121 caagggcatg tcgtcgggat cattccacag tttttgaaag atcgagaagt agctcatgat
      181 cggttgagcg agttggtcgt cgtcgataca atgcatacgc gcaaggcgaa aatgaacgaa
      241 gcagccgacg ggtttatcgc cctgcctgga ggatatggaa cgtacgaaga gctgtttgaa
      301 gtactgtcgt ggtctcgcgt cggccttcac caaaaaccga tcggcctgct caatgtggac
      361 ggcttttttg acccgctcct cgacttgctt cggcacacgg ttcaacaagg atttgccgcc
      421 ccacaagatc tcgagctgat cgtgagtgcc ggggatgttc cgacgctata tgagcggatg
      481 agcatgttcc gccatcgtcg tgggcagcga tgatggcggg gtggtttgcc gctaagtctt
      541 taagccggcg aattgtttac ttcatatgcg gcgcagatgc cggattcaat ggctccttga
      601 atccagccat ggtgcgtgga agtatgttcc ccagcaaaat gaacccttcc ttcgggggta
      661 gcaatatagg gggaaatctc tgttatttga ttcggcttca tcagtgtaaa ggcgccgccc
      721 gagtatggat agcgtaccca gctatgactt gttccggttt caaattcgcg gtacacttgt
      781 tcaccataga ggacggctaa gttttttaac gtgtattcga gccgctcttc agcgcttaag
      841 ctgtcccacg ggatcgtgtc gtcttcccac gtatagctgg ccaatacgac gcctggtcca
      901 gtcgtgccga tgccttggct tggatattgg gtgtagcgaa ttggcaaatc ggacactgtt
      961 cgtcccccga acaagccttc tttttcccaa aaacgtgttt taaactggat gccggttttc
     1021 gttgaaccga cataatgaag ttcgcgaatg gcttttcgtt tattctcgga aaacgaatgg
     1081 cgtggttcaa tgtcgacaaa ttgcaaaatc gaaaacggga tggtgacgat cactcgatcg
     1141 gctgtgattt gaaatggctg aagaattttt gtatggatcg catgaatggt gacactgttt
     1201 ttgttttgga caattttttg cactttatgg ctaaagagca gctcatcctt cagttgcggc
     1261 aaaaaggcct ttggaagccg atcgttgccg ccaacaattt tataaaagcg catgttcggt
     1321 gtaaacaatg tcatcagttc gcgcaacagc ccaagaaacg acaattccgg gaatccttcg
     1381 agcgagagga ccgctttgat catatcgata gcacctaccg atagccttag gccgaacggg
     1441 ttgtaacgca aataggtgtc aaacgagtag cggtcgagct gttcgatgac aatcggccaa
     1501 tgtttctctg ggttttgttc aatgaattga atgactgggc gaaccgccat ttgcaatagt
     1561 tcggaagccg ttttgcctcg ttcataggaa gcgatgggaa agccaaagag gtcgggatgt
     1621 cgttcgtatt cgctaaggcg cgctttgata ccgcgaaaat acaaaatgtc gcgcggagtg
     1681 ctgttgacaa aagggtggat cggcaagttg aacttttgga tgtattccaa cgtcaagcgg
     1741 tgggtgtgtg gaatgcgcat cgcgcccgct tcgaaatact ggtcatcgcg aaagtcggat
     1801 cggatcgtgt agattcggcc gccgacccgc tcagatgcct caagaatggt gacgcgatgg
     1861 cccgcctgtt tcagcagtga tgccgccaca agcccggcca tgccagcacc gataacgacg
     1921 atctttttcg gtatggatgt tttctttaac ccgtttcgaa taatcgagat catcgtctcc
     1981 atgggcagtc tcggagaaat atagggatgc gccacgtgtc aatccccctt tgccattttc
     2041 actacatttg gatgaaacta cggttattcc atcctattca gcagcaaagg gggatatgtg
     2101 aaaagcatct gtcacgattc agaaacgata tacgtccctc cagctagctc gaagcggcgc
     2161 cttggctgaa tgccggcgat ccgacataaa aatggccttg ttgacgggcg atcgtcggct
     2221 ttgtaaaagc ggagagcgat gccgccaacg gttagctccg catatgttcc ctcttcatcg
     2281 tgcctaacct cgggtaccgg caagccaaac agccggcggt agccgtcgat ggcgcgatcg
     2341 agatcgagcg tatagaggct aatcgacgac aaagaagggg aaccgatcgg gtggcgcatc
     2401 agcggcgcca attcattcat ccgcatgtcg tcgctgtcgc cccattcgat gaaaaacggg
     2461 taacggaacg cgccgcctgt gtcgtcttca agaaacagca ttgaccacgt gagtaacttg
     2521 ccgtcatcgc gctggcgact gccagggaac ggcccgattg gggtgaatcc tttgttccgt
     2581 agctgctttg tcaatgattc gatatcgttc gtccggaacg ctaattgaga aaagccactt
     2641 ccctcttggc tgtcggcgac aagcagggtg atgagcggat ttccgcatgt gttcgccgtc
     2701 tgcatgtcag cgatgccgat ccattcaatg tagcagagcg gtttgaaata gcacaatgcg
     2761 ttatacgttc cccatgacaa atggcggccg ccatgggagg ccgtaaaccc taattgctca
     2821 aacgctgctt tcgcttgttc ggggcgctcg gttaaatgaa cgagatggtc aaacgcgata
     2881 ttcatggcat tgggctcctt tcctatatga aaatggatca gtaggacagc acttcttttc
     2941 gtttgacaga tgatgcattc gttatcgacc gtacggtggg cgatgaaatc taagtccaac
     3001 tggatgtctt cgatttgagg ccaatgattc ggcacgggaa tctatgtttt gttcgaggtg
     3061 gtttctaaac cgagaaggtt cccaccttca cgcatgagca caagtggaag atgaatcgga
     3121 gcctttcacc aagcgtggaa cgtataagga tgtcttggtt gacagcctgc tgtggcgagc
     3181 attctcaagc atctcccatc tttaagtgta aacgtaggtg gggggagtgt tcaattctaa
     3241 tgaagcgctt tctcgtaagg cgatgtgcat cagctgcaag agcatcggtt ccctcttggc
     3301 gatgaagaaa gggcggaaac gatgctgtgc cattcttttc cccagcgtga agcaaacctt
     3361 ggtgttgacg ccgttattat tccaagcgga tctcttgttg tttctcacgc atttctgact
     3421 gttccggctg aatggcgatt tattgccgct cgagttgttt ttgttgataa actgacgcaa
     3481 tgggacatcc atcgtgttcg ggctgtcgag cgcttaggca agcgatgttt cgttcatcgt
     3541 tacaagttcc tttttatcag ttatggcgta tatgttcgtg tatgtccatt gacaaccact
     3601 caaattggtc cggaatgttg ctttatttcc ttaaattttg gtatcatcat agtattgtgg
     3661 aaggtcgacc atgtcggagg tgaatacgat gtcgcgaatt tcgattgaac aagtaaaaca
     3721 tgtcgcggat ttagcgcggt tagcgatgac ggatgaggag gcggaactgt ttacgaaaca
     3781 gcttgacgcc atcattacat ttgccgagca gttgaatgag ctggatacgg aaaatgtacc
     3841 gccgacatcg cacgtgctcg atatgagaaa cgtgatgcgc gaagatgagc cggagcctgg
     3901 actgccgcgt gaagaagtgt tgaaaaacgc gccggatcag caagacggcc aattccgtgt
     3961 accagccatt ttagagtaag gagggggatt tatgtcgctc tttgaccata cggtgtccga
     4021 attacatacg ttattgcaga aaaaagaagt gtccatttcg gatttagttg atgaatcata
     4081 ccgccgcatc ggcgaagtgg aagaaaaagt acaagcgttt ttaacgttaa acgaagaaca
     4141 agcgcgggcg aaagcgaaag agcttgacga caagctggcg aaaggcgagg aaacaaaccc
     4201 gctgtttggc ttgccgatcg gcattaaaga caacattgtc accaaaggac tgcgcacgac
     4261 atgtgccagc aaaattttat ataactttga tccgatttac gatgcgaccg ttatggaacg
     4321 gctgaatgct gcgggcgcga ttacgatcgg gaagctgaac atggacgagt ttgccatggg
     4381 ttcgtcgacg gaaaactccg ggttccagct gacgcgcaac ccatgggatt tggagcgcgt
     4441 tccaggcggt tcaagcggcg gttcggccgc ggcagtggcg gcaggcgaag tgccgttttc
     4501 gctaggatca gatacgggtg gttcgatccg ccagccagca gcgttttgcg gagttgtcgg
     4561 attgaagccg acgtacggtc gcgtttcgcg tttcgggctc gtcgcgtttg cgtcgtcgct
     4621 tgaccaaatt ggtccgatta cgcgcacggt agaagataat gcatatttgt tgcaagtgat
     4681 cgctggcgtt gacccgatgg attcgacgtc ggcgaatatt gacgtgccaa actacgttga
     4741 ggcgttaaca ggcgatatca aagggctgaa aatcgctgtg ccaaaagaat atttaggcga
     4801 aggcgtcgcc gaagaagtac gccagtcggt gcttgcggca ctcagtgtgc tggagaagct
     4861 tggagcgaca tgggaagaag tgtcgctgcc acattcgaaa tatgccttgg cgacgtacta
     4921 tttgcttgct tcgtcggaag catctgccaa ccttgcccgc tttgacggtg tccgctacgg
     4981 ctaccggacg gacaatgcga aaaacttgat cgatatgtac aaacaaacgc ggagcgaagg
     5041 gttcggcagc gaagtcaaac gccgtattat gcttgggacg tttgccttaa gctcgggcta
     5101 ttacgatgcg tattacaaaa aggcacaaaa agtgcggacg ttaattaaac gcgactttga
     5161 aaatgtcttt gaacaatacg atgtcatcat cggtccgacg acgccgacgc cagcgtttaa
     5221 aatcggcgag aaaacgagcg atccgctgac catgtatatg aacgatattt taacgattcc
     5281 ggtcaacctt gcgggtgtac cggcgatttc tgtgccgtgc ggctttgttg atggcttgcc
     5341 ggtcggcttg caaattatcg gcaagcattt tgatgaaagc acggtctacc gtgtcgctca
     5401 cgcctttgaa caagcgaccg attaccataa gcaaaaaccg gtgttataag gggggataga
     5461 cgatgaattt tgaaacggtc atcggacttg aggtgcacgt cgagctgaaa acaaaatcga
     5521 aaattttctc aagcagcccg aacgcattcg gtgcgccccc gaatacgcaa acgaacgtca
     5581 tcgatttagg gtatccgggt gtgctgccgg tcttgaaccg gcaagcggtc gagtttgcga
     5641 tgaaggcggc gatggcgtta aactgcgaaa tcgcgaccga gacaaaattt gaccgcaaaa
     5701 actattttta tccggacaac ccgaaggcgt accaaatttc gcaatacgac caaccgcttg
     5761 gcaaaaacgg ttggattgaa attgaagtga acgggaaaaa gaaaaaaatc ggcatcaccc
     5821 gcatccatct cgaggaagat gccggtaaat tgatgcatac aggcgacggc tattcgcttg
     5881 ttgactttaa ccgtcaaggg acgccactta ttgagatcgt ctccgagccg gacatccgct
     5941 cgccggaaga agcgtacgcc tacttggaaa aattaaaagc gatcatccaa tataccggcg
     6001 tttccgactg caaaatggaa gaagggtcgc ttcgctgcga cgccaatatt tcgcttcgcc
     6061 cgctcggttc ggacaagttc ggtacaaaaa cggaattgaa aaacctcaac tcattcaact
     6121 tcgtccgcat ggggctcgag tacgaggcga aacggcaaga gaaaattttg ctctccggtg
     6181 gcgtcatccg tcaagaaacg cggcggtttg acgaagcgac gaaaacgacc gttttgatgc
     6241 gcgtcaaaga aggttcggaa gactaccgtt acttcccaga gccggatttg gtcatgcttt
     6301 acattgacga cgaatggaaa gagcgcgtcc gcgcctcgat tccggagctg ccggacgccc
     6361 gccggaagcg gtatgtcgaa gagtggggct tgccagaata tgacgccaaa gtgctcacac
     6421 tgacaaaaga aatggccgac ttctttgaag cgaccgttgc gaacggcgct gatccgaaac
     6481 tggcgtcgaa ctggctcatg gtagaagtat ccggttactt aaactccgaa caaaaagagc
     6541 ttcatgacat cgccttgacg ccggaaagtc tagctgggat gatcaagctc atccaaaacg
     6601 gcacgatttc gtcgaaaatc gcgaaaaaag tgtttaaaga gctcgttgaa cacggcggcg
     6661 atccagagaa aatcgtcaaa gaaaaagggc ttgtgcaaat ttccgacgaa ggagcgctgc
     6721 gcaaaatcgt gctagaagtg ctagatgcca acccgcagtc ggtggaagac tataaaaacg
     6781 gtaaagaccg tgcgctcggc ttcctcgttg gccaagtgat gaaagcaacg aaagggcaag
     6841 cgaacccgcc gcttgtcaac aagctgcttg ttgaagaaat caataagcga taaatcaaaa
     6901 gacaaggctg ctgaccggca gccttgtctt tttattttat tttttagact tttaaaaaaa
     6961 tacaattgac atccctcaat ggaaatgata gatttttaga caaaaccaac tgaattagtt
     7021 ggatatagac atcaagagga gcgagagagg aagaatcaaa acagagaggg atgagaacga
     7081 tgagtgaaga acgtgcattc cgcccagaga cgctcgccat ccatgcgggg caacaaccgg
     7141 atgcagaaac aggttcgcga gcggtaccga tttatcaaac gagttcgtat gtattccgtg
     7201 acagtgagca cgcggccaat ttgtttggat tgaaagagga aggatacatt tatacgcgta
     7261 ttatgaaccc gacgaacgat gtgcttgaaa agcgaatcgc ggcgttagaa ggcggcgttg
     7321 gagcgctggc gctgtcatcg gggcaggcgg cagtgtttta ttcgctcatc aacatcgcct
     7381 cggcgggtga tgaaattgta tcgtcttcgt ccatttacgg cggcacatac aacttgttcg
     7441 cccatacgct gcgcaaattt ggcattacgg tgaagtttgt tgactcgtct gatccggaaa
     7501 actttgagaa ggccattact ggcaaaacga aagcagtgtt tgctgaaacg atcggcaacc
     7561 cgaaaaacga tgtgctcgac attgaagcgg tagctgatat cgctcatcgc cacggcattc
     7621 cgctcatcgt tgataacacg gttgccagcc cgtacctgct gcggccgatt gagtttggcg
     7681 ctgatatcgt tgtccattcg gcgacaaagt ttatcggcgg gcacggcaat tcgatcggcg
     7741 gtgtcattgt cgacagcggc aagtttgact ggaaaggaag cggcaagttt ccggagttca
     7801 ccgaacctga tccgagttat catggtttgg tgtatgtcga tgctgttggg gaagcagcgt
     7861 atatcacgaa agcgcgtatt cagctgttgc gcgacttagg ggcagcgctg tcgccgttta
     7921 atgcgttttt gcttttgcaa ggattagaga cgcttcattt acggatgcag cgtcatagcg
     7981 aaaatgcgct cgctgttgct aagtttttgg aagaggaaga agccgtcgaa tccgtcagct
     8041 atccagggct tccaagccat ccgtcacatg aactcgcgaa aaagtatttg ccaaacgggc
     8101 aaggtgcgat cgttacgttt gaaatcaaag gtggcgtcga agccgggaaa aaattgatcg
     8161 actcggtgaa gctgttctcg catttggcca acatcggtga ttcgaaatcg ctcatcatcc
     8221 acccagccag cacgacgcac gagcagctga ccccggaaga acagctgtcc gccggtgtca
     8281 ccccaggtct tgttcgcctg tctgtcggca cggagtcgat cgacgacatt ttagaagact
     8341 tacgccaagc cattcgccaa agccaaaccg tggcggtgaa gtagtgggca tcaacagatg
     8401 cgtatacaac actaccatga aatttaggga ttgagaagtg agggctgaac taaaacgcac
     8461 gcgcgttttg gatcagccct gcttttttac tcccaaagaa gaattgagct cattctagtc
     8521 ggatagcgac tgccatcaaa agaaagatgc cttttttata tggaaagagg atagatcatt
     8581 gacacacttg tggtgtagaa attcgtgagg ggtgtgctca ttttaaacgt gcaactgtac
     8641 gaagtgcaga tctaatgttc attgaataat caaatggaag tgattgagcg aaccgaatag
     8701 tgccctgtat ttgaaaagaa tgcggagcgc tttcgtgtag cggtcttcct cgttacgtca
     8761 actgcaccat cctgatcttg aacaagcaag tcgtcatgta gaagatgttg tgtattttgc
     8821 caataacctt ttgagatagt ctcgtataca caataaattt aagaacatta taaaaaatat
     8881 atacaaatac attagaaaaa tattagaatt tccatttatg ctaaatgtcg aaaaaaggtt
     8941 ttttgttttg gcattaacta tttgatgaaa aaggcaggaa ttcataatcg ttttgtacat
     9001 ctttcatcaa gtagttaatg ataaatatca acaataaaaa ggaggaaatg aaagaatggc
     9061 gaagtttgat gattttgatt tggacattgt ggtgaaaaaa caggacgacg tggtacaacc
     9121 gaacgtgacg agtaaatctc tttgtacgcc aggttgtatc acaggtgtgt taatgtgtct
     9181 cacgcaaaat tcttgtgtat cttgtaactc ttgcattcga tgctaatggt ttcgattgat
     9241 cacacattca ttgaaccatg tgagcgttaa atcacgctaa caaggtcgat cataggctaa
     9301 cttccgacaa aaaagaaaaa gggaatttgg cacttacatt cacccttgat cgacaatcgt
     9361 caaggaggag aaggattagt aaggacaagg gcagaaataa agaggataag aagcccttgt
     9421 ccattcttga tttttcctta gatcatcttg gaatggtcca tgactcatta tatctcgggt
     9481 gagacagaca tgatagggcc acccgatgtt tttgatgaca tcaagcataa aaaacaagca
     9541 atgctaatat cttttgactt gcatatacat ctcgcccgct cagaatgaaa cagaccggat
     9601 tattttatga aagaaaaaac tgggcgataa aagggattgg agtgataacg tttgctacat
     9661 gtagttgcgt taggcacgac tgatttgcgg ccctacccca tcagaatgtt gtgaacccac
     9721 agacaggtgt cattattcct cagtctgttg tttcaaaaac aaagtcgata agtttgaagg
     9781 aagggcaaac tgctcaaaca tgaagtatca caacaatttt tgaaacaccc cgcaaaaacc
     9841 aaatgtcgtt tcgaaagcaa cacaagattg ggccgccagc tttctgcttc gtacgaggca
     9901 gaaggtgtca gctgctttag tatggaatgt atgtatagtt ccgtatagaa tcccctttta
     9961 acttatggag atggtgaatg attgagtagg aggctttatt atgaacgatc ttgtctttaa
    10021 aaacatcgat acgtttatga ttcgaacacc ggttttatca gtagacaact atttaagatt
    10081 ttttgatcaa aaattgactg agggagaaat gaaagagcgt ctgttggaaa tttgtcataa
    10141 ccctgtattt agagagagta tcttagtagc gagtaaaagt ttatataata aaatgattga
    10201 tttttgcaac ggcaaggaaa taaaaaaata cgattatttt atcaaagcca tttataagta
    10261 tttgataaga attagcacga gaccaacgcc atttggtctt tttgcaggag tagactttgg
    10321 tgaatacacg gatgaaaata catcaataag atatggaacg aataaatata agaaatttgc
    10381 taggccagat ttagaatggc tgatgaagat tataaagaaa ttggaacaag aacaatatga
    10441 gcaattatgg ttcacggtga atgacagtat atttttaaaa ggagaacggg catatttact
    10501 acattcgaca cgaaaagacg atgacaagcg agtcaatgaa atcagcgtca gagtcaccct
    10561 tccttttaaa atcacgtgtg aattagctcg tcacttgatc cattaccaaa cattaaaaaa
    10621 agaattaata aaacaatttc caaatacgag tgaggaaaaa attgaacgtt ttctcaagca
    10681 actaatagaa aacgaatttt taatttccaa tctccgccca ccattaacag taatggatca
    10741 gcttgattat ctgataaagc gattgaaaga aagccatata gaagagtgga gtaacgaatt
    10801 aattgatatt caacaaaaga ttcgcacata taccatgacc ccgttaggag aaggggagca
    10861 aatatataaa gagttacata aaaaaatgaa aaagttagcc gataccaaaa atgtgttaca
    10921 agttgatatg aagttaaact tacaagaaaa gaaactgaac aagcaagtga taaaagatgt
    10981 aaatgaacta atgcacatac ttctaccttt ttcgatgacc tatcaacaaa cagattctcc
    11041 actttcgagg tacaagcaag aatttatcga aaaatatggg gtggacagag aagttccttt
    11101 actagaaatg cttgataatg atcttggtat aggagcacct atggattata caaacccgaa
    11161 aaacgcaaga ctcgctgtag gtgtgcccca tcaattgatt gatgagcagt taagagaata
    11221 ttttcttcat aaatatatcg aggcggttaa agacaaaaaa agtataacaa taacagaaga
    11281 cgagataaaa gaattgggtc tagatgatta tgattaccaa agcatcccgg attcattaga
    11341 cattaacgtc attgtaaaat gtgactcgga acaagatctt gagaacaatc atttcaaata
    11401 ctatattggc cctaatttag gatcgaccca tgcggggaaa agttttggaa ggttttctta
    11461 tatgatggaa ggggaagaga aactcttcga aacgttaaat aaagaaatgt tgaacttgaa
    11521 taatgatagt ggcgagtatg taacttgtga gcttgtttat ttgccaaatg aaacgagaca
    11581 tgccaatgtg acaagaaata ttcataacag cgaatacgaa cttgcgttgt ttactaacaa
    11641 cagcaaagat gaatatcatc gattgagctt aaatgatatt ttgatcggca tagagaacga
    11701 tatgttttat gccaaaagca aaacactaaa taaaaagttg attattacta tgaataatat
    11761 gttgaataca caaaatgccc cgaatgcgat tcgttttttg tatgatataa gcttagatgg
    11821 caaaaaaatt tggtgtaatt tcccttggga tacaatcttt caagactatg cttacatacc
    11881 ggcaattgaa tacaaaaatt tcgtcatagc accgcgaaaa tgggtgatca ataagattat
    11941 taaaacaaac gacaaaatta gttttacgga atttgaaaaa cgctttaaaa aattttgttc
    12001 tgattatgat gtgccgaaat atgtttattt gacttttgca gataatcgga ttttgttgaa
    12061 tacagaggat gaaaattgtt taagaattct tcatcacgaa tttaacaata gatacggaaa
    12121 cattattcta agttcttatg aagaggctga tcttcattta gttaaagatg atgacgaaaa
    12181 agagtatgtt tgtgaattgg tcattccgtt agtgaaagtg aaacaagaaa atcgtcaatg
    12241 gtatgccaaa gcgaaaaaat caaatcatat cccaagtttt tcagatataa gagtcaagtt
    12301 gccttttgaa aattggcttt atttaaaatt gtacggtgtc cattctagag cggatgattt
    12361 catcgccttt tatctttcag aatattgtcg cgaaaaattg gctaaaggag aaattgaaaa
    12421 atatttcttt atacggtatg ccgacccgga gcaacatata agattaaggc tgaatgccag
    12481 tgaagagaaa cttctacaga tttatccgga tatgaaacaa tggctgcgaa cgttaatcga
    12541 aaaaagagtg gtgagtcgtt tttccatcga ctgctatgaa agagaaattg agcgttatgg
    12601 tggaacagaa ttgatcgatc ttgcagaaaa cttatttttc ttcgatagca tagtagtaga
    12661 ggacatatta aagttaaaac gtttgaaaca tattcaattt agcgatgaag tgatcggaat
    12721 ggtttccatc attcattata tggaacagtt cggcctaaat tatgaaagtc aattggattt
    12781 cttgcaacag caagtcaaca aacaagacta tcgtgaagat tttcaaaaga atcgatctgt
    12841 ttacatgaaa gtttgtaata cggataatga ttggcaaggg ttaagagaca ctgatgaggg
    12901 gatgttatta ttaaacgttt tgaaccaaag aaacagaagc ataaaagagt atgcaagcaa
    12961 gatccaggac ggtctcgaag cttcttctga attatctatt ttagacagtg tggttcattt
    13021 acactgtaac aggctattcg gcattgatcg agaatttgaa aagaaaatcc gtacattagt
    13081 tgcccatacg ttatatgcat taaagtatat taaagctcat ggattagtgt taaaaaatta
    13141 aagatgttat ccatttgtcc aagcattggg gagacgatat ataaatggac ccacgacttg
    13201 gacttttttc aacaaaagct cgacaagctc tcttctgtgt attcaggtga aaaaactttt
    13261 atgacgggaa gaagatctca ttttagcatg cggggattga aaatgttatg aatataaaag
    13321 agtatgatga tcacgttact atcaaagata ttgtgaaatc aataaggata gttcccaaga
    13381 cgcttgttct tataaagaac gttgacaaac aaagtttttt tatcattatt ttcttaagct
    13441 tattaatggg aggcgcaccg attgttacat tgctcggttc gcaaaacttg ttgaatgcaa
    13501 tcgggtccca aaatattcat attattatat cggcattgat cttttatatt tctgctgttt
    13561 tactcagcga gatcatcagc agtttcatgg aatattacca aaataagttt caaactctca
    13621 tcaactacaa acttaatttg caaatcatgg acaagtgtac aagattgtct ttacggcatt
    13681 ttgaggatgc cgaagtttat gatatgttgc aaagagtaca gaatgaaacg ccgtataaac
    13741 catttgaagt gtttttatcc atattaggtg caatatcggc gattgtaacc tttttttcat
    13801 cgatgatgat tctgatccat tggaaaccgt gggtgttgat tatattaatc ttcataccac
    13861 tcgttttttc tttttatttt ttcaagattg gccaaagaga gtttaatgtt agttggttgc
    13921 gtgcaccgga aaaaaggaaa tcatggtatt tgtcttacct aatgacaaga gacaacacgt
    13981 tcaaagaagt caaaatatat aacttggcag gctatatttt gaacaaattt aaagaaatca
    14041 acaaaacgtt cgtcgggcag gatatccatc tttttaaaag aagaacggtt tttacattta
    14101 tttttgagct cgttgaacaa atatgtatca ataccgtact tgttatcatc atcatttcgg
    14161 cgttggcagg tgaaatcctt ataggtcacg tcgtggggct tattcaggcc ttgaacttaa
    14221 tttctagcaa ctctaagaaa atattgaata tcatccattc cttgtataaa aacaatttat
    14281 atatcaacca actgtttgaa tttttggggt tagacgaaga agtattggac aaaggagatc
    14341 gattcgtatc agggatagac aaaatcgaaa atattaagat aagaaattta acgtttcgtt
    14401 atccaacgaa tccaaaagta gtattgaaaa atattaacct cgacatcaac aaaggggaaa
    14461 gaatagccat cgtcggtgca aatggatcag gaaaaagcac ccttataaaa cttttattga
    14521 aattgtatga gcacgatgag gatagcattt tttataatgg tgtgtccatc aatgatttgg
    14581 atacggaaca attgagaaaa aacattgccg tgttgttcca agattttgtg aagtatgaat
    14641 tgaaattaag ggaaaacgtg gggtttggcg atattacgcg cattgatcgt gacggagaat
    14701 taaaacaagc catggagagg gcgagagtaa attttatcga ggatttagat actcagcttg
    14761 gtttatggtt tgtcgacggt gttcagcttt cgggaggaca gtggcaaaaa gtagcgattg
    14821 ctagggcgtt atttcgggat gcatccgtat atatattgga tgaacctagc tcggcactgg
    14881 atcccatttc cgagaaagaa gtcattgata tgtttatcaa tatgacaaaa gataaaattg
    14941 gtatctttat ctcacatcgt ctatcaacag ctaaacttgc cgataaaatc gtagtaatga
    15001 atgatggtga aattgtcggt ataggtacgc attgggaatt gttagctacg aatgagttat
    15061 acagaagaat gtatgaattg gaagctttga aaaacgagga ggagtatgag catctcaatg
    15121 aaagcgctgg tttgtaatct tgcgaaaaaa ttgtcggatt atgagaatat gaagcgaatc
    15181 gtcaatcacc caagtaatta tattaaaatt ggaaacaaga cgataaatcc gtttaatgag
    15241 ttaagtttaa gccatgggtt accagcctta tgtgcgctgt acggcgaatt gagcgaacaa
    15301 tatccggatg aaggttggga tttattaggg catcaataca tgaaaaaaat cggtgaacaa
    15361 atgaatcaac acggtttccc ttctttatct atgtttaccg gattggcagg gatcggcctt
    15421 gctgcagtat gtttatccaa gggaggaaaa aggtatcaaa actttatctc aacgattaat
    15481 caagtcatcg aagaaagaat cggagaaatg atcgagtatt tgaaacagaa accgtatccg
    15541 aatatggacg attacgatgc tatttcggga gtagcgggta tagcgagcta ctgcctatta
    15601 tttccgcaag agatgaaaaa aagtattacg ttaatcttaa aatacattat agatttatct
    15661 caagataaac aaatggagga tatcaacgtt cctggctggt atattcctcc aatgaatgct
    15721 ttttcagaca ccgaaaggag aaaatggcca tcgggtttct ttaacattgg gttgtctcac
    15781 ggtatacctg ctttactcat tgtcttgtgc aatgccaaaa aactgaatat ttacgtacat
    15841 gggcaagatg aatgcattca aagaatagct gattttctta tgaagtttca aattaaagat
    15901 gaaaatggct cttattgggg gactcatgtt tctctagagg aatacaaaaa tggctctgtc
    15961 ctaaacaaag atacaaggga tgcctggtgt tatggcacgc ctggtgttgc ttattcgtta
    16021 cttatagcag gtaaaactct aaataatcaa tcatacattg attgtgctgt cagcggaatg
    16081 aaactggcaa gcaaacggct ttacaacatt ttttctcctt ccttctgtca tggtttatcg
    16141 ggagttgcgt atatatgcaa cagattttat gaagaaacga atatcagcga ttttaaggaa
    16201 gccgcctgca aattagtcga tgatataata aaattttata atgaggaatt cccttttggc
    16261 tttaaaaata ttgaggagag cgaaggaagc acgaaatatt atgattatgt gggactaatc
    16321 gatggaacag cgggaatttt attgacgata ttagctatac aaaactcgaa aaaaacgcct
    16381 tgggattgtg catttttatt atctgaagtt taaatgttgt ttatatacaa tggaaaagcc
    16441 gactgatcga tggttggagg caagccgcag agggggttcc atcatacctt ggcgtaccga
    16501 tcggtcgaac aactccctaa aaagggtgtt gttcgatcga ccagtcatcg atcaaatatg
    16561 ttggaaaagg ttcatagaca agaggcgtct ttcacccggg cgtcactcaa gacgtgcgca
    16621 ttttttagta aaaagcaaca aagagtaaag cttcacattg cacctatgaa caaacgcaac
    16681 ggtgttatga gattacccca tgatatgggg atggaatagg ttaaaatgcg attcaactgt
    16741 atgggggatc aaaagatgaa taacaagaaa attttggtcg ttgatgatga tgaagatatt
    16801 tgctgcacca ttaaacaata tttggagctt catcattatc aggtagaaac ggtccacagc
    16861 ggcgtagaag cgttgaagat gataaacgac gattttgatt tgattgtgtt ggatatcatg
    16921 atggaaggaa ttgacggaat ggagctgtgt acaatcattc gtgatcgggt tgattaccct
    16981 attgtatttg ttagtgctaa aacgctggag gaagataagg ttcaagctct ggcgatcggt
    17041 ggggatgatt acatcaccaa accgttcagc ttaaaggagt taaaggcgag aattgattct
    17101 catttaagaa gggaagaacg gattcgttca aacgagagat atcttttgag ttctaaaaat
    17161 attacgattg atcttttggc taacgaagtc ttttgtaaag gaaagaaatt accgttaaca
    17221 aaaaaagaat atgagattgt taagttgttg atgctcaata aaaaggtcgt tttctccaaa
    17281 gaaagaatct ttgaacgagt atgggggatt gactccgaca gccagttaga cactgttaca
    17341 gaaagcatta aaaatattcg aaagaaaatc aaggccgtcg atccagaaac ctcttatatt
    17401 caaacattat atgggctcgg ttataaatgg gatgtgaccg atgaaaaaga ataaaacgat
    17461 taaacgagat ttttatttgt tagttgtgaa agtcgtgttg gcaacggcaa tctcttcggc
    17521 cgttacttat ttatgcttaa tctatttgat tattacatta gccacgaacg atgtggtgaa
    17581 accgacaaat tatttcgtga aggatttgga tttgattgaa aaaaaggtga aagaaaacga
    17641 agaggcgatt ttcaagggga gattaattcc catccatcgt tacagtgaaa agatacaggg
    17701 agaagttgta gacatcagcg gtaagcatct gtatggtgat cgagaaatta tagacgatca
    17761 agtggatatt agtcaatcga tcaaccgtga gattgtaaaa ggaagctatg tgtatcggtt
    17821 cattcccttg aagcatgata acgccattca ggcggtatat gtgttgaaag cgccttttgg
    17881 gttcatcatt aacaatcaaa atcgcttcga agccgtgttg atttatgctg tgatgtttat
    17941 ttctccgttg atctttttta ttgtctattt gattttcttt acatctaggc tgtacaaatc
    18001 attgtttcat aatgtcaaac tgttgctcca ggcttcggat cacattgcaa gcgggaattt
    18061 tgattttcaa gtctcggggt tgaaaagaaa agagtttatc aagatccagg attcctttaa
    18121 taccatgatc agtgcactga aagaaatggt ggaacgttta gcaaagaccg atgacgaacg
    18181 aaaaatgatg gtatcatcga tcgcacatga tatcagaacc ccgttaacgg tcatccaagg
    18241 acaaattgat ttgattcaag atttgagaaa gttggaccac tttgatgtca ctccccattt
    18301 agagattatt cgcaaaaact gtgggaagat gaccatgttg acagataatt tgtcgttgct
    18361 ctataaagtg gagaatgacc acttctcatt gaatggaaaa gaagtggatg taaggcaaat
    18421 ccttgaggag aaaaaactag agatctcaac aatggtttac catcaaaaat cgataaacat
    18481 ttgctttgat gtgaatttgc aaaaatcacg ttacatactt gatgaagcga tgttaatgag
    18541 agtgttggac aatattttat acaacagcct gaggtttaca aaaagcggag aaattaagtt
    18601 ggaagtctat gatgaaaaag aggggaatga gtgtaaaatc tattttcgct gttcagatac
    18661 aggaacgggg tttaaagaaa acgatacgtc tttgttgttc cagccttttt accaggataa
    18721 gcagtataaa aatcatgttg gattaggact gtatattgcc aaacgaattg tgaatcatca
    18781 tggcggtgaa atttgggcct acaacaatga aaaaggcgga gcgacggttg aattttatat
    18841 taaggagcta tctgattaat catccaatct tatgggcttt ccgccgttat agagagtgga
    18901 gaatgcagct agggaggaat ttctctttcc ctagctgaca gtctctaagc ctttattttc
    18961 ttttagcaat caaaaattgg tggttcaccg taacagccac ttcttcatct gggtttacgc
    19021 ctttgatgct gtatacccaa ccaaagttca agtgagttcg tttttcatcc gtttgatcgg
    19081 gaatgacttc gatctttcgc agctcttttt tactcaagat ttgatgatgc tcattgatgg
    19141 taatcgtctc cgctactttc ccgatcggtt tgttcaattg attccgatcg acttttgctg
    19201 cttgaatcat gtacgttcgg ccttgatagt gaatttcttg caaattttct ttgttcaact
    19261 cgtattttgg taatttccga tcgatctcca tattttgtgt ggctgtcttt tttaagtcac
    19321 tgacaagtga acaacctcct ataaagagga ttccaatcaa catgaggagt aagatggagt
    19381 ttttcatcgt tactctgaaa cctccttttt taccatccca ttgagaggga gcagtgaact
    19441 ttcattcatg tggttgattt ccttcccaac gatgaaacca gatcgaaccg atgatggtga
    19501 cgatgatgaa gcttagaagg gcgtaggcta ttccttccca taatgatagc gaaaaggaat
    19561 ttaacaactg cgcccccaag gcttgcttta cttcgggcat cataagaatc ggaaattgtg
    19621 agagacgaac agcccaagcc caaggaatat agctccatac gtgatcgcct aaggaagttg
    19681 cgccaatcag ggcggaaatg agaaatccgc cgcttcctac tgcgatcgag gctcccattc
    19741 caaaggcaaa gctgatgaac agatgcaagg aaaaaaggat gagtgagccc acgatggaga
    19801 gcatggctcc ttgcaaaaat aactgataat gaatgtgcgc cactttgagt acgtatttca
    19861 ttccaaagag catgagaatc gtcgctagca agatgtccgc gcatgcaata aagatgagca
    19921 gcgtgagttt gccaacatac cattgaactt tggatacagg accggtcaag atgttcatga
    19981 aacttcctgc tttttcttct tgataggaca tcagcccagt cagtagggag ataatgatcg
    20041 gtaaggaaac ggccattact tcaaaaaatc cttgatagat tttcatctgc caaaacgtag
    20101 aggtacggta gtgcgaaaaa taccatacca taaagagcga ataaatgatt ggcgtgatga
    20161 tgaccatcat ccgaatcgct gtgcgttttg tttttatcca ttcggatgac agaaggcgaa
    20221 gaaaccacat gttaatacac ttcctttcgc gcaaaccaaa cggcggttaa aaaagataac
    20281 aatagaaaca tgacaagggc aatcgccagg cctattggaa tgacagaagg atccaatagc
    20341 ggactccctt tttccaaagg aacaccgttc ggatgaaccc cgacgatcgg gcacatcatc
    20401 ctcattcccc agctccatgg gatgaacagc caatacggtt gtgcggccat gactacccct
    20461 aaggcgaggc cgatgacact gacaatgatc gagactacca tcccgaaccg ctcggccaca
    20521 aataatccga tcgggatata ggctaaagag gtcaaccaaa tgaccaagct ggcgaatacg
    20581 gcgaccgtag ctgatgagag gctgttggga aaaagccatt tcaataaaac aagcaagatg
    20641 atcagctcta ttgttgagag caacatgtaa taggcgatga cggtgatttt gctccaccat
    20701 agacgcacga tgctaatgtc gtgacaacgc aatactttat cgtttcctga ctttttctcc
    20761 cttaccgttg acaaggaagc gatcaaggct gttccaatcg gaacaaaaat caatggccac
    20821 caattaaata cggcatattc gaaataattg tgtgtggaat ttacagttgg catggtgatg
    20881 atggcgtaca ggacaaagaa aagcggagcg atgaatacaa gttttttcgc aaacgtccgc
    20941 ttatatttta aacgttctga ctcgaacata ttgagcatga tttccatcct ccttcattac
    21001 tcgttcacta catcgacaaa gagtttttcg agatcttgac tttcgtctat tttcccttcg
    21061 tacctgagtt ttccgttttg gataatgcca atataatcgg ctaattgctt aacttcggac
    21121 aaaatatggc tcgatagaat gacggtgatc ccgttttcgg taaacgattg aatgagtttt
    21181 cgcaagtcct gtatgcctaa tgggtccaag ccgtttgttg gttcgtcgag aatgatcagc
    21241 tttggatggt ttaaaagcgc tttggcaatt cctaatcgct gtttcattcc gagggaaaat
    21301 tgagatgctt tctttttccc tgtattttct aagccgacga tgttcaaaac ttcttggatc
    21361 cgcgactcag gcaaatgaag caatttagcg tgaacaagca agttttcatg agccgttaga
    21421 ttgccgtaaa gagcagggga ttcgatcagc acaccgatat cttttaagtc ttttctgctc
    21481 caaggatggc cgttgatcat gatttcccct ttcgtaggac gcaaaagccc tgtcagcatt
    21541 tttaaaaggg ttgactttcc ggctccattt ggtccgagca atccataaac cgtctgtttc
    21601 ttgactttaa tggatacatc atctacgacg agttgtttcc caaacgcttt gcttacatga
    21661 tgggtctcta acatatactc tcccatgttc attctcctcc tatatataga aaattgggtg
    21721 gtgatgttgt ttttagctgg cattagtgaa aggagcgatg gcgatatccg tgctgtgttt
    21781 catattaatg gctcaatgta atgtttttat aagaaaatga gcacatggat gatgtttttt
    21841 atagattggg cttcgtacct tggtttatcg tttgctgttg ccgtgatcag cgctcttcac
    21901 tgaccagtga atgaaaatga ttggaagtat cgatggattt gagcgattaa gttgatgtca
    21961 catgtggtga ggaaacaaaa tggtcaacgg ggctgttgtg gttcatacat agggagtggg
    22021 aggcggatga atcatcataa ggggtagtgt ccattttcat ggtgaggtgg ttgactaatg
    22081 aacaaaacat atcatttgtg ggggggggga atcacccacc ccacaatgat tttcaaatct
    22141 tatttatggc agcaaaaact ggatcgaact tcctccgttt tgtatcctta ctcaaataat
    22201 cattgacaag cattcatttt gattagtacg aacgtcaggg gttatatcta tataaatatt
    22261 ctcgcccgct tcggggcgag taagcagggg agagtggtgt tcgaattctt gttggggtgg
    22321 cgtcaaaggg ctgattacag ctacagccct tttggcgtca ctttcttttc cactttgcgc
    22381 agcaaccagt caaacacaat cgccaaaatg gcagctggga tggcgccggc taaaatcaag
    22441 tttttatcgg cgatacgcaa accgcggtcg atcaagtcac caagcccgcc agcgccgata
    22501 aacgtcgcta aggcggcgac accgatcgtc aacaccgttg ctgtgcgcac gccggccata
    22561 atgaccggaa gagagagagg aagctcgacc atccataaaa tttgtcgcga tgtcatcccc
    22621 atccctcgtc cggcatcaac gagcgccggg tcaacgccga gaatgcccgt gtacgtgtta
    22681 cgcaaaatcg gcaatagggc ataaagcgtc aaggcgatga tcgccggcag tttgccaatg
    22741 ccgaaaatcg gcaacataaa cccaagcaat gctaagcttg gaatcgtttg gatgatggcg
    22801 gcaatgccga taatcggctc agcgagtttg cgataccgcg tcaacaccac accgagcggc
    22861 acggcaaccg caatggcgat gcccatggca atagcagata acagtacgtg ctcttgaaaa
    22921 gcgatccaaa tctcttcttg tcgttcgata aacgtttgca ataattccat tgtacccctc
    22981 cttggtggaa aaacagcggc agatggatag ccgcttggtc atcgtgttat tccttccttg
    23041 gtgaaacaat cgttggcaga tggactagtt ttcccccttt ggggaaaagc gacgggaaat
    23101 gagccgcgac ttcatcatgg tatgccattc ggcagaaagg cggcgggtca gccgccactt
    23161 cgttctcggc tgaaaccggc cgccaaccgg atgagtgatt tcagcggcta cttttcaaac
    23221 aagcagtcgc atccccttgt ccataaacca cttatcagca gttcaaccct tattttaatc
    23281 gagccatcgt ttcaagcggt ttgccaacaa gatggacaga aacgggacat tcctctccac
    23341 ctatatctca ttcatttttt tatgcatgtt gttgaaatgt ccactcagca agcgcgcgca
    23401 tcatgcttga gcgcgtaata ccgccgacaa gacggtcgcc gtcgagcacc ggaatgatgc
    23461 gcacatccga gtcttggaac aaagcagcga cgtcggtgac acccgcttct ttttgtaatg
    23521 tcgtcacatc gtaatcagcg atatccgcaa caagcaaatg ttcctcattg tatcgttgtt
    23581 cgatttgttt gagtgtcacg atgccgagaa acgagcgctt tttatcgacg acaaccaaac
    23641 tgtctacttt tctcgctttc attagccgga acgcttcagc taagccacgc cgtggcgaaa
    23701 tcgttgcgac gtcatcggac attaaatctt ccgctgttgg cacggctgtt tggcgagttc
    23761 gcatttgcag ccggtcttca ccaataaatt cgcggacaaa cgagttcgct ggtcgccgaa
    23821 gcatttggtc tggcgtcgca aactggacga tttcaccgtc tttcatcagc gcaatccgat
    23881 cggcaatttt aatcgcttcg tccatatcat gggtgacaaa gacaatcgtt ttgtgaatct
    23941 cctcttgcaa acggatgatg tcatcttgca gctgttcacg gctgatcggg tcgagagcgc
    24001 taaatggctc gtccatcaaa atgatgtccg gttcagcagc caaggcgcgg acgacaccga
    24061 cgcgttgctg ttggccgccg ctgagctccg acggatagcg atgcttgaat gtcgctggat
    24121 ctaagccgac gagctcaagc aactcatcga cccgcttttc ataggcgtgt ttttcccatt
    24181 ttttcagctt cggcacgagc gcgatgtttt ccgcgatcgt catatgtgga aacaagccga
    24241 tttgctggat gacatagccg atgttacgcc gcagttcgac cggatcaagc tcagaaatgt
    24301 cttgtccatc gatatacact tttcccgatg tcggctcgat taagcggttg atcatccgca
    24361 tcgttgtcgt tttcccgcag ccgctcggcc cgatgagggc aaccagctct cctttacgga
    24421 tttcaagatt gatatttttt aaggcaacga acccatcttc atactgtttt gttacgtttt
    24481 caaaccgaat catccacatt cctcactttc tagtcgatca gtccttccga tttcaagaag
    24541 tcaatcgcca ccttgcgcgg ctgtttccct tctaagttca cttcgccgtt gagttccatc
    24601 attttttcgt cagttaaaat attcgctagt tgattgagtt tttcttccaa tcccgggttg
    24661 gcatccaaca cttcttggcg gatgatcggt acggcgtagt atggcgggaa gtactgttta
    24721 tcgtctttga gcacaacgag gtcatatttc ttaatacggg catccgtcgt gtaggccgtg
    24781 atgacatcaa tctttccatt tttcgctgct tcgtattgca agtctggatc gatgttgacc
    24841 gttttcttga agtggaatcc gtacgtatcg acaagcccat catagccgtc gcttcgctca
    24901 aaaaactcgg cgtctgaccc aaatgtgagg gaagatgaat ggttcactaa atcggagtac
    24961 gttttaactc cgagcttttc agcaaggtct ctccgcatcg ctaatgcata cgtattgtta
    25021 aatccgagtg atttgagcca agcgatgttg tatttttcct tatataattt cttcgtttca
    25081 ttgtagattt gttcgggcgt tttcgttgga tcgtacggct gttttaaaat gtttaaatac
    25141 cctgtccctg tatattcaac atacatgtcg atgtccccgt tttcaatggc ttgctgcaac
    25201 ataaaggcac cgcctaaact ttccttcacc tcgacatcca aatcggtgtt ggctttcaca
    25261 tattcagcta gtacatgcgt caaaatcatc tgttcggtaa acttctttcc ggtaatcacg
    25321 attttccctt tcgcatcact ttttccgctg caggcggcca atcctaaaac aagcccgaca
    25381 gcgagcaaag acatgaacca ttttcgcaac ataattcctc ctttttctgc tagtatcata
    25441 ggggagaaga gaataaaaaa agcggcaaaa tgacgcggag gggtgaaaag cgtcataata
    25501 aaagggtaac gtaatatggg ggtagctggc aaatttggta tcggccgatc tgtccgtctg
    25561 tcgcttgctc ttgtagtgat cagtgttctc tcctccttga tgcttataaa tgctcgggaa
    25621 tgctctcaga tcctctcgaa tactccgaac tcaagatatt ctggttgacc ccaatgttac
    25681 cgccgccccg tcagtttacc ggtctcccga gcgggctcgc caagctcgcc ttcgtcatcg
    25741 ccgaaagctt gcagcccatg gccaagaaga tgaagcagcg ccaaacagca ggcggccaag
    25801 aggtggccct cgggcggctg ttgttcggat gtttcgagac atagtttgcg attgtgtgaa
    25861 gaagaggagc tccaattgcg aaatgaggtg agcgaaataa tgaatagaat ggatggcctc
    25921 gtacgaacag tggggaatcg tgaaagaaaa gatacatatt gcgaagcgaa tgctgacgca
    25981 agagatataa cgtgaaggcg attagtgaac tgacccgatt gtcggtggca gtggtgggaa
    26041 aactgaaaaa gtagaagatc catgtgagga cactaagaag caagattcgt ttgtcgtcga
    26101 cctccaatcg tgcaaaaacc ccagggggtc gacgacattt gtgtttgtca ctgggttcct
    26161 acagctatcg caggcgagcg ttattgacgg aattttttta ctgtgttatt ctgaaggcaa
    26221 caagggatga aaaaacttga tataacagca ctttttgggt ttgtatcgta cctatgaggg
    26281 attgaaactc tgtcgatgaa ctgaattttt atttcgcctg cggtttttat cgtacctatg
    26341 agggatcgaa acgcctctgc ttataaataa agaaagaagg aattatagaa agcagggtat
    26401 tctcatgaga ctg
//
