LOCUS       NC_007777              21334 bp    DNA     circular CON 05-SEP-2024
DEFINITION  Frankia casuarinae, complete sequence.
ACCESSION   NC_007777
VERSION     NC_007777.1
KEYWORDS    RefSeq.
SOURCE      Frankia casuarinae
  ORGANISM  Frankia casuarinae
            Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
            Frankia.
REFERENCE   1  (bases 1 to 5433628)
  AUTHORS   Normand,P., Lapierre,P., Tisa,L.S., Gogarten,J.P., Alloisio,N.,
            Bagnarol,E., Bassi,C.A., Berry,A.M., Bickhart,D.M., Choisne,N.,
            Couloux,A., Cournoyer,B., Cruveiller,S., Daubin,V., Demange,N.,
            Francino,M.P., Goltsman,E., Huang,Y., Kopp,O.R., Labarre,L.,
            Lapidus,A., Lavire,C., Marechal,J., Martinez,M., Mastronunzio,J.E.,
            Mullin,B.C., Niemann,J., Pujic,P., Rawnsley,T., Rouy,Z.,
            Schenowitz,C., Sellstedt,A., Tavares,F., Tomkins,J.P., Vallenet,D.,
            Valverde,C., Wall,L.G., Wang,Y., Medigue,C. and Benson,D.R.
  TITLE     Genome characteristics of facultatively symbiotic Frankia sp.
            strains reflect host range and host plant biogeography
  JOURNAL   Genome Res 17 (1), 7-15 (2007)
   PUBMED   17151343
REFERENCE   2  (bases 1 to 5433628)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Goltsman,E.,
            Martinez,M., Schmutz,J., Larimer,F., Land,M., Kyrpides,N.,
            Lykidis,A., Francino,P., Benson,D.R., Huang,Y., Mastronunzio,J.,
            Bickhart,D., Niemann,J., Rawnsley,T., Tisa,L.S. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2006) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000013345.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 02:41:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,755
            CDSs (total)                      :: 4,702
            Genes (coding)                    :: 4,516
            CDSs (with protein)               :: 4,516
            Genes (RNA)                       :: 53
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 53 of 186
            Pseudo Genes (incomplete)         :: 162 of 186
            Pseudo Genes (internal stop)      :: 10 of 186
            Pseudo Genes (multiple problems)  :: 37 of 186
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:46:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4770958
            Orig. end                         :: >4792292
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000249.1.
            URL -- http://www.jgi.doe.gov
            Source DNA and bacteria available from Louis Tisa
            (lst@patia.unh.edu)
            Contact: Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..>21334
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="22"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..>21334
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>21334
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:>11334](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..>11334)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    949..965
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     misc_feature    1301..1317
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.33"
                     /tool="antismash"
     misc_feature    complement(1357..1375)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.71"
                     /tool="antismash"
     gene            1417..1950
                     /locus_tag="FRANCCI3_RS20140"
                     /old_locus_tag="Francci3_3988"
     CDS             1417..1950
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS20140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Francci3_3988"
                     /product="hypothetical protein"
                     /protein_id="WP_236701424.1"
                     /transl_table=11
                     /translation="MARLRSEGYLVCSGSSPVPVEVRGVRPDGVGLLFRCRGTAIRLAL
                     YRPGRAVWQIAVRDKAWCPEESLQLWTHHPLGTPDVPTDARLAFPRGTEPDQELVIDGA
                     RVWGWCGHEAGLLRPAAAAPLFDRLMATVARSGGARSGLALSDRIQPDLTREVAVPAAR
                     SRARGKEGISISIS"
     tRNA            2033..2109
                     /anticodon=(pos:4773025..4773027,aa:Ala,seq:cgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="FRANCCI3_RS20145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="Francci3_R0054"
                     /product="tRNA-Ala"
     gene            2033..2109
                     /locus_tag="FRANCCI3_RS20145"
                     /old_locus_tag="Francci3_R0054"
     gene            2201..2497
                     /locus_tag="FRANCCI3_RS28380"
     CDS             2201..2497
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS28380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_035958066.1"
                     /transl_table=11
                     /translation="MGQLRLADVSSVYVGDVPWSVGSEDLEDRCEPVGSGDLYFGDQGF
                     DESLASEVVACLDNRFDVPGDCAKAGTGRHNGFVVDLFGEFGLPLAELLLLGA"
     gene            complement(<2768..3784)
                     /locus_tag="FRANCCI3_RS28385"
                     /pseudo=""
     CDS             complement(<2768..3784)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.5"
                     /locus_tag="FRANCCI3_RS28385"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="recombinase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRSTARRTTAKRTKQAVAAQPEIVRVGIYLRRSTDDENQPYTIE
                     AQEERLRSYVDSQPNWIVALRFADDASGATTERKDLQRALAAARNGLIDVLLVYRVDRL
                     SRSLRDTVDLLEELEQAGVVFRSATEPFDTATPIGRMLLQILAMFAQFERDMIIDRVIA
                     GMERKAAKGLWKGGRRPFGYQVDKIAKKLIIDVAEATIVRLIFDLYVRDRLGTRAIASV
                     LNNRGLRTTVGGPWSGHKILRMLDNRAYLGELTFREITVEGTHEPIIDEETFDAAQKIL
                     TERSEETSRRASNPSDYYLTGRMRCPQCGTALIGTRATGRNHTYRYYTCHTRNRYNRH"
     gene            complement(3899..5089)
                     /locus_tag="FRANCCI3_RS20165"
                     /old_locus_tag="Francci3_3990"
     CDS             complement(3899..5089)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011434597.1"
                     /locus_tag="FRANCCI3_RS20165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3990"
                     /product="ISAs1 family transposase"
                     /protein_id="WP_011438364.1"
                     /transl_table=11
                     /translation="MPVGALSRDAAGVVGAGAVSREGIWQRLHAMGEHRGRRGRVYPLA
                     VLAAVWLCALTAAGHDRVTAVIEWLAGTTEEERRRLRLPYDPFDGYRLPSESTIRRFLN
                     DTDDARLARALLDPPLADPAPPKPASPEAAGEAVRAVYALDGKTSRGAKRADGRQVQLV
                     GVADQATGRLVNQHEVDSKSNETKAFRPVLEPLDLACDLLTFDALHTVRDHLDWLVTDK
                     KAHYLAVVKGNQPTLRAFLAALPWADVPVADTTHDHGHGRDETRTLKAATVEHAEFPHA
                     RQAVRIQRWRREKGRKPSRETVYGITDLAFEQASAGFLADAARGQWIIENRQHHVRDVT
                     FGEDASRSRTRRGPVNLAIFRATVAHAVRAAGHRYVPAGRRACKTATAALDLHGFP"
     misc_feature    complement(5167..5182)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.28"
                     /tool="antismash"
     gene            complement(5424..5936)
                     /locus_tag="FRANCCI3_RS20170"
                     /old_locus_tag="Francci3_3991"
     CDS             complement(5424..5936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438365.1"
                     /locus_tag="FRANCCI3_RS20170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3991"
                     /product="hypothetical protein"
                     /protein_id="WP_011438365.1"
                     /transl_table=11
                     /translation="MKREEGQDLTRIGVTGHMDLTPATVPLVRAALTAALMPYAPDLTG
                     VSCIAAGSDSIFADVVLDIGGTLEVIIPAADYRARKVKPDHAPLFDDLVRRAATVRVLP
                     HEVSDRAAYEAANEALLDTVDLLIAVWDGQAAADQGGTAAVVARAQANDRAVQVIWPTG
                     AARQRHL"
     gene            complement(5933..6577)
                     /locus_tag="FRANCCI3_RS20175"
                     /old_locus_tag="Francci3_3992"
     CDS             complement(5933..6577)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438366.1"
                     /locus_tag="FRANCCI3_RS20175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3992"
                     /product="hypothetical protein"
                     /protein_id="WP_108913875.1"
                     /transl_table=11
                     /translation="MFCANILAGMARQQFYLGRTTEGLELVRLAQDVAGARATPAVRAM
                     LFTREAWAYAQQGRLSAFRRVTGRAQDALRDVDPGVEPHWISYFDQAELAGVTGGRLLD
                     VAHQAPEYADEAATWLSQAVRARGVGSVRSTALDQLGHAEIRLVQGEFDEAARLGHAAV
                     TTVEQTRSSRVRVKLGQFYRHAETRTSARPIAELCGRIKPMLRAEDTAARI"
     misc_feature    6620..6633
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    6999..7013
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(7036..7047)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.08"
                     /tool="antismash"
     misc_feature    7076..7085
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    7217..7237
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.63"
                     /tool="antismash"
     gene            complement(<7229..7625)
                     /locus_tag="FRANCCI3_RS25015"
                     /pseudo=""
     CDS             complement(<7229..7625)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020460419.1"
                     /locus_tag="FRANCCI3_RS25015"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRPSQRVEQDELRARMRAVGMSHDEIAIEFGRRYRLRPRAAHRV
                     AHGWTQQQAANHINTHAVHVGLDPHGAAPMTAPKLSELENWPLPNNRRRPTPQILALLA
                     EVYDTSIHNLIDLDDREHFDPADLLLID"
     gene            complement(7716..8252)
                     /locus_tag="FRANCCI3_RS20180"
                     /old_locus_tag="Francci3_3994"
     CDS             complement(7716..8252)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438368.1"
                     /locus_tag="FRANCCI3_RS20180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3994"
                     /product="flavoprotein"
                     /protein_id="WP_043590376.1"
                     /sec_met_domain="Flavoprotein (E-value: 2.2e-11, bitscore:
                     41.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHLVVCAAPPAAQVDELIRHVHTDGWAVCLVPTPVATTWLDVHA
                     LEELTGHPVRSRPRRPDEPRLPPADAVVVVPATFNTINKCAAGINDNAALGVMNETIGL
                     GLPVVIAPYVKPTLAAHPAFARALRDLTTYGFTVLPTNAIGPPDGTTSFAWRPVLNSLP
                     ARRPAGEISAPEDPS"
     gene            complement(8267..9859)
                     /locus_tag="FRANCCI3_RS25020"
                     /old_locus_tag="Francci3_3995"
     CDS             complement(8267..9859)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438369.1"
                     /locus_tag="FRANCCI3_RS25020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3995"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_085949882.1"
                     /transl_table=11
                     /translation="MSKLSRRVEQEELRARMRAVGMSHDEIAVEFARRYKLRPRAAHRH
                     ARGWTQTQAANHINTHAARVGLDPDGAAPMTGPKLSELENWPLPNNRRRPTPQILALLA
                     EVYDTSIHNLIDLDDREQMPPADLLLITTIRERAVPASAIGSLPQAQSASSEVTPMVDA
                     PNRQQFLLAASALGVAVVLPRQPAAPSPSVSVRSTVFPAACDLLADLREAITAPAEWST
                     DPDPASFAGPADLDARARECHDRYQRADYAGTARLLPAVVRGIETLTVDPPTGVNHRAV
                     RRTQAVAYIAAAKLATKTGDHDLAWLAADRGQHAALAADAPALLATARRQIACVFHDTG
                     RLADAERVAVSALDALNQRPGDEDHRDLSSARGALLLLSAMTSIRRGERTEGRRRLTAA
                     AEQADALGRDNNRLWSAFGPTNVAIHTLTATLVLDDPTEAVGVGEQIDTRLLPPPLAGR
                     RARLHVDLSGGHARLGEDAIAAVHILDVARRAPQLLRVDPTARAVLATLLGRARGSTVS
                     VLRSVAEQAGVAT"
     gene            complement(10001..10783)
                     /locus_tag="FRANCCI3_RS20195"
                     /old_locus_tag="Francci3_3996"
     CDS             complement(10001..10783)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438370.1"
                     /locus_tag="FRANCCI3_RS20195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3996"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_035959242.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9e-25, bitscore:
                     85.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEETPWKQVNITYPAEDPAERERQAIAHLTEILPPAEAGGLITSW
                     WFIRKGPWRIRYLLTDTAGGRHSDATDPLHPLLTKGVIWTDDIYEPEVHAFGGPASMDL
                     AHSLFHADSRRLLSALGDGCTDRRERSLLLCTKLMRAAGLDINEQGDVWARVAEQRAAL
                     AGVPPDPQIWASFTWDVRRLLLGDARADLTDGDWLTAFHETGRALRTLRENGQLTRGIR
                     STIALHVIFHWNRIGLAATTQATLARAAKEAVFDNAPG"
     gene            complement(10798..>11334)
                     /locus_tag="FRANCCI3_RS25025"
                     /old_locus_tag="Francci3_3997"
                     /pseudo=""
     CDS             complement(10798..>11334)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006544852.1"
                     /locus_tag="FRANCCI3_RS25025"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3997"
                     /product="lanthionine synthetase LanC family protein"
                     /pseudo=""
                     /sec_met_domain="LANC_like (E-value: 4.7e-14, bitscore:
                     50.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSDGIKVDGQTEAITRICWWLDAWEQQKPGGGSWWPQIVTLTDLD
                     RGTTSQLGPLRPSWCYGTPGIARSQQLAARALHEPARQRRAETAFLDCLNDPTQLSRLT
                     DRSLCHGTGGLLATARNIAADALTPISLTQPQLLHQPAAAEDDEPPGFLVGSAGADLAT
                     TATTTTSWDACLLLR"
     gene            11437..12273
                     /locus_tag="FRANCCI3_RS20205"
                     /old_locus_tag="Francci3_3998"
     CDS             11437..12273
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435557.1"
                     /locus_tag="FRANCCI3_RS20205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3998"
                     /product="IS5 family transposase"
                     /protein_id="WP_011435557.1"
                     /transl_table=11
                     /translation="MAERKPYPSDLSDEAWDLIRPVLTAWKARHPSASGHEGGYDMREI
                     VNAVLYQARTGCQWRYLPHDLPPTSAVYYYFGQWRDDGTTETIHDLLRWLVREHHRRKA
                     DPSAVVLDSQTVRSSTNAPKGTTGLDPGKKSPGRKRGIAVDTLGLLIAVVVVAASVHDN
                     TIGTALLDRVAAAAPPVRKAWVDAGFKTTVVEHGAGLGIDVEVVGREPGARGFTPLPKR
                     WRVEQTLGTLMLHRRLARDYEAKPASAVAMIHWSMVEVMARRLTGAATPTWRDPPV"
     misc_feature    complement(11438..11450)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            12292..12735
                     /locus_tag="FRANCCI3_RS20210"
                     /old_locus_tag="Francci3_3999"
     CDS             12292..12735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438373.1"
                     /locus_tag="FRANCCI3_RS20210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_3999"
                     /product="hypothetical protein"
                     /protein_id="WP_011438373.1"
                     /transl_table=11
                     /translation="MTSGVPVREVLEQIEARRARAGRAVEELREEIARLTGQLAAAERA
                     LERLEITRETVLDLAAENDAAPAEPLPPGYREVLAVFTRGGNGLHAKDVCRALGGGTEP
                     RHVESMRARLKRLVERGVLTEPDPGLFVLPRPDPPATPEINSS"
     gene            13170..14891
                     /locus_tag="FRANCCI3_RS20215"
                     /old_locus_tag="Francci3_4000"
     CDS             13170..14891
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011434965.1"
                     /locus_tag="FRANCCI3_RS20215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4000"
                     /product="IS66 family transposase"
                     /protein_id="WP_237704547.1"
                     /transl_table=11
                     /translation="MTVVESGAGAAASGEVAEGAALLAENAWLRARVAELLTDIAGLVA
                     REATREAEVVELRLQLEALQAELATLRRMLFGRSSERECGGSPAVGSPDGGDGCGDGAR
                     GEAAGSAGRRRGPGARSGRRSYDHLSRDEVDCDFEGGGYGCLSCGQPFTPWGEHVVEQL
                     DWLVTVRVRVSRRRRYRRGCRCGGSLTVTAPGPSKAIGKGLFTHRFLAMLIVERYVAGR
                     SQNSLVTGLARHGAQLSPATLTGACAQVAGLLAPLAEQIVGRSRGSWHLHADETTWRVF
                     TPTGGGGPARWWLWVFLGPDSVCFVMDATRSTAVLAEHVGLDPDSGQLTDDADGGPRRL
                     VLSSDFYTVYVSAGRRADGLVNLYCWAHARRYFVRAGDANPAQLGIWARQWVERIRALY
                     TAHGELAAAWHTAAAAPSPATEKRLAAAYAGWDTAITVIDTVRREQTASPGLQEPARKA
                     LATLDREWDGLVAHRDYPMIGMDNNPAERAIRGPVVTRRNAGGSRTEDTARHAATIFTV
                     TATAAMHNLNLLTYLENYLDACGRAGGKPPTGADLDRFLPWAASPEDLTTWQQPPG"
     gene            complement(14943..15239)
                     /locus_tag="FRANCCI3_RS20220"
                     /old_locus_tag="Francci3_4001"
     CDS             complement(14943..15239)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS20220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Francci3_4001"
                     /product="AMP-binding protein"
                     /protein_id="WP_011438374.1"
                     /transl_table=11
                     /translation="MGSLPGAPAAAPFYLGDLLAEAADDNPGMTVTTNHPLNLVDGGRD
                     RREFTVAELAGVVDKTAHRLYAAGVRPADQVAVIMTNGFDVVLAYVFGNPVGA"
     misc_feature    15277..15293
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            complement(15313..15933)
                     /locus_tag="FRANCCI3_RS20225"
                     /old_locus_tag="Francci3_4002"
     CDS             complement(15313..15933)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044569.2"
                     /locus_tag="FRANCCI3_RS20225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4002"
                     /product="DUF6875 domain-containing protein"
                     /protein_id="WP_011438375.1"
                     /transl_table=11
                     /translation="MSDDHTAEKTVNSWFRSYLARPHPMLGRLGAVCPYVRPALDGDQI
                     RLWTLDLPKPIFASWLEDRVREAIRLFPALFWQPELSLPALVLAFPDMGEQDWPLIDQV
                     HSIVKSEAVSLGLMIGQFHGSCTEPSARNQDFHVNVSPVPLFAIRRMSVHDILFLHSRP
                     DWFAVYRDRFGDHYRGERTQTGILAELYSAAEERFFGTPLCPA"
     misc_feature    16241..16254
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.48"
                     /tool="antismash"
     gene            16406..16939
                     /locus_tag="FRANCCI3_RS20230"
                     /old_locus_tag="Francci3_4003"
     CDS             16406..16939
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438376.1"
                     /locus_tag="FRANCCI3_RS20230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4003"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_011438376.1"
                     /transl_table=11
                     /translation="MRLSQGIEWALHCCHALAEAPDGSSLPVQQLAALHGGNPAYLAKH
                     LQALSKAGVVVSVLGPRGGYRLGRPADQIRLLDVVDAIEGSSPVFLCTEIRQRGPAALP
                     PANYRAPCAIAAAVSSAEDAWRQALASTTIADIVTASRRQAPEAVTATARWLRETVDAR
                     SRGQADEQNRKADG"
     misc_feature    complement(16976..16995)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.46"
                     /tool="antismash"
     gene            16981..18270
                     /locus_tag="FRANCCI3_RS20235"
                     /old_locus_tag="Francci3_4004"
     CDS             16981..18270
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="FRANCCI3_RS20235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4004"
                     /product="MFS transporter"
                     /protein_id="WP_237704548.1"
                     /transl_table=11
                     /translation="MTRPPVEASSASTREVRLDGAPPNSTDHGDAPCPRPETRDRQRWG
                     ALITGWLALFVIGTDLFVVSPLLPIWRSRFDVSLRTAGLTVTVFALAYVVAAPAWGRRA
                     VKVSPPAVLVLALSGFAVCNVLTALAPNFWTLLAARVGTGLFISGATATVFTLVASSAP
                     NGRRASWLGIATSGLLSALWAGAPLGGLVARHTSWRAVFVILAAFAVLILVAARRIWPD
                     TQAARAAAAPASRSAAWRARAVAPTACWAAAVYGLYTYLSAGLGDRPGWSTAWLNASLI
                     VYGLCAVAATFLGGRIADRHGAARTTWTALLLLAAADVAFSASLSSAAVTTCLAIALLA
                     FAAYTAFPAKQAQLVSDHPADSAQLMSWNQSAMYLGITLGSLAGGRIADGHFRALPLAC
                     AAVAILGATTQVSTVRRRTPAGHAADSDRW"
     misc_feature    complement(17004..17017)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(18354..18548)
                     /locus_tag="FRANCCI3_RS20240"
     CDS             complement(18354..18548)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS20240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_035959288.1"
                     /transl_table=11
                     /translation="MFFDYDADSLRSAVADAIGDLHEDTLGRYWVTDMLTTAWRVYVTH
                     AGHSPRSAWDRELATKWRR"
     gene            complement(18624..19067)
                     /locus_tag="FRANCCI3_RS20245"
                     /old_locus_tag="Francci3_4005"
     CDS             complement(18624..19067)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011438373.1"
                     /locus_tag="FRANCCI3_RS20245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4005"
                     /product="hypothetical protein"
                     /protein_id="WP_011438373.1"
                     /transl_table=11
                     /translation="MTSGVPVREVLEQIEARRARAGRAVEELREEIARLTGQLAAAERA
                     LERLEITRETVLDLAAENDAAPAEPLPPGYREVLAVFTRGGNGLHAKDVCRALGGGTEP
                     RHVESMRARLKRLVERGVLTEPDPGLFVLPRPDPPATPEINSS"
     gene            complement(19086..19922)
                     /locus_tag="FRANCCI3_RS20250"
                     /old_locus_tag="Francci3_4006"
     CDS             complement(19086..19922)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435557.1"
                     /locus_tag="FRANCCI3_RS20250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4006"
                     /product="IS5 family transposase"
                     /protein_id="WP_011435557.1"
                     /transl_table=11
                     /translation="MAERKPYPSDLSDEAWDLIRPVLTAWKARHPSASGHEGGYDMREI
                     VNAVLYQARTGCQWRYLPHDLPPTSAVYYYFGQWRDDGTTETIHDLLRWLVREHHRRKA
                     DPSAVVLDSQTVRSSTNAPKGTTGLDPGKKSPGRKRGIAVDTLGLLIAVVVVAASVHDN
                     TIGTALLDRVAAAAPPVRKAWVDAGFKTTVVEHGAGLGIDVEVVGREPGARGFTPLPKR
                     WRVEQTLGTLMLHRRLARDYEAKPASAVAMIHWSMVEVMARRLTGAATPTWRDPPV"
     misc_feature    19909..19921
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            complement(19988..20335)
                     /locus_tag="FRANCCI3_RS20255"
                     /old_locus_tag="Francci3_4007"
     CDS             complement(19988..20335)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019846.5"
                     /locus_tag="FRANCCI3_RS20255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_4007"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_011438378.1"
                     /transl_table=11
                     /translation="MLDGAAARTGQDLLDLSLGARLTPAALAAVVPGGSVTTLAPTRAA
                     LSQIRPTPENSQTWGSVWDLAERPLPLPDASFDAVIGFSVLAPLRHPRRMLTDITRVLS
                     GRSARFRRVSA"
     misc_feature    complement(21193..21208)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.61"
                     /tool="antismash"
ORIGIN
        1 gggtcgccag caccacgtgg gtggctccct gggcccgcac gacctggcac gcggcagagg
       61 ccgtcgagcc ggtcgcgatc ccgtcgtcca ccacgaccac cgtccgcccg gcgagcggga
      121 tccttggccg gccgttccgg aaccgccggg tccgacgatc aagctccacc aactcgcgcg
      181 cctgaaccgc ggcgaactcc tccggcccca cgttggccag ccgccgggcc tcctcgttga
      241 cgacccgcac cccaccctcg gcgatcgccc ccatcgcgag ctcaggctgg aaggggacac
      301 cgagcttgcg gacgaggatg acgtccagcg gggcctccag cgcccgcgcc acctcgaacg
      361 cgacgggaat gcccccgcgg ggcagcccgg cgacaacgac atcacgaccg cgtagatgcg
      421 ccagccgctg cccgagctgc cggccggcct cctcccgatt atcgaagatc acgacaacct
      481 cctcgtgccg gccgggcgga ctcctcgtgc tcgccgtccg gaccggacat cgtcctgtgg
      541 ttgtcgttcc ccggtagtcg ccgggatacc gacccacacc gtctcggggc acctgccccg
      601 agacgagcga tacacggcgt gcggcgcgcg gcgcgcggcg cgtggcgcgt ggttcgcggc
      661 gcgtggttcg cggcgtgcgg cgtgcggcgt gcggcgtgaa gatcgtcaag gcactccgga
      721 cagccggaat caccgtgtcc gcatgggcct gaaccgatct ccggcggcca cttgcgctcc
      781 gacgcccggc cgggctgccg tgcataataa agatgtgacg ctccgttggc agcccggctc
      841 cacccctcac tgggcgtggc gagaggtctg ttgtccaggg cgctgtcggt gttgtcccag
      901 ccctcgcgtc cactgagcct cgccgcacgc gcgacgagca catcggtcct gtaattctgg
      961 gaccgttctg ggcgcgaggg gcctcggagc tcggcgccag acctgaacgg atgatctttt
     1021 tgctcccggt gggagcagct atcgatcatc cgtattcccg gactcccgtc ctgccccggc
     1081 cggttcgttc accggagtgc tccgtgtgcg ctccccggat aaccggctga gctgtgcgct
     1141 ccgccggatg agccaggtcg cgccgtctcc gtcttctccc gtcacacgcc agcccgctgc
     1201 ccgccccggt cacctgtggc cgcgccgcca gggccagccg ggctgatccg gccctggcgg
     1261 ctggtccggt cctggcggct ggtccggtcc cgaccggccg atcccccgat ggggcttccc
     1321 agaccagcgc aactactgcg taatcatcac gtaatcactg tgtagctatc gagaactatc
     1381 aggaaggcag cgttcgctgt gaccttcgag tcgtggatgg cccggttgcg gagcgaggga
     1441 tacctcgtct gctcggggag ctccccggtg cccgtcgagg tacgaggtgt tcgtcccgac
     1501 ggggtcggtc tgctgttccg ttgccgggga acggcgatcc ggctcgccct gtaccggccc
     1561 ggacgggcgg tatggcagat agccgtccgc gacaaggcgt ggtgcccgga ggagtccctg
     1621 cagctgtgga cgcaccaccc gctcggcacg ccggatgttc cgaccgacgc ccggctggcc
     1681 ttcccccgag gcaccgagcc ggaccaggag ctcgtcatcg acggcgctcg ggtgtgggga
     1741 tggtgcggcc atgaggcggg gctgctccgg ccagccgccg cggcccccct gttcgaccgg
     1801 ttgatggcca ccgtcgcgag gtccggcggg gcgcggtccg gcctcgccct gtcggaccgc
     1861 atccagccag atctcacccg ggaggtcgcc gtgccggccg cccgatcgag ggctcggggc
     1921 aaggagggca tcagcatcag catcagctga cggccggccg gaggtggcga tccatccgaa
     1981 ccgggtggtc gtcacatggg ctacgcggtc ctgtaagctt cagatgcttc cagggggtgt
     2041 agctcagcct ggtagagcgc ctccctcgca cggaggaggc caggggttcg agtcccctca
     2101 cctccaccaa tgtaggcatt gcgcgaaccg ctcccttcgg gggcgttgtg gctggtagga
     2161 cagctgcggc gcccctgtgg ggggcggggg acgtggctgg ttgggtcagc ttcggctggc
     2221 tgatgtctcc agtgtctacg ttggtgacgt cccttggagc gtcgggtccg aggaccttga
     2281 agatcggtgt gagccggtcg ggtccggtga tctttacttc ggcgaccaag gcttcgatga
     2341 gagccttgcg tccgaggtcg tcgcctgtct cgataatcgt ttcgatgtgc cgggtgactg
     2401 cgcgaaggct ggaacgggcc ggcataacgg gttcgtggtc gatctcttcg gtgagttcgg
     2461 cctgccgttg gcggagctgc ttctgcttgg tgcgtagtgc ttcgaggcgt gtggcgaggg
     2521 tctcgtcgtc gagggtaccg cgctcgaacg ccccaagata acggtcgatg gcctggtctg
     2581 tcagggtgag ttccgtctca atggtgctga gttcggccgt gtgttcggat cgggcgtcgc
     2641 ggtggctgcg ctgggctttg aggacggcgt cggcgatgag ctgctggtgg tcgcggtaga
     2701 agccggcaag agcggtgagt acggcgtagt cgacggcgtc ggcgtcgagg cggggggcgt
     2761 cgcattcgtg gcggttgtag cggttgcggg tgtggcaggt gtagtagcgg taggtgtggt
     2821 tgcggccggt cgcgcgggtg ccgatgaggg ctgtgccgca ctgggggcag cgcatccggc
     2881 cggtgaggta gtagtcggag gggttggagg cccggcgtga ggtctcctcg ctgcgttcgg
     2941 tgaggatctt ctgagcggcg tcgaacgtct cctcgtcgat gatcggttcg tgggtgcctt
     3001 cgacggtgat ctcgcggaag gtcagttcac ccagataggc tctgttgtcg agcatgcgca
     3061 ggatcttgtg gccggaccag gggccgccga cggtggtacg caggccgcgg ttgttcagga
     3121 cgctcgcgat ggctctggtt ccgaggcggt cgcggacgta caggtcgaag atcagccgga
     3181 cgatcgtggc ttcggcgaca tcgatgatga gctttttggc gatcttgtcg acctggtagc
     3241 cgaacgggcg ccgtccgcct ttccacagac ccttggcggc cttgcgttcc atcccggcga
     3301 tgacccggtc gatgatcata tcgcgctcga actgcgcgaa catcgccagt atctggagaa
     3361 gcatgcggcc gatgggagtg gcggtgtcga acggctccgt ggccgagcgg aacacgaccc
     3421 cggcctgttc gagttcttcg aggagatcga cagtgtcgcg caggctgcgg gagagccgat
     3481 cgacgcggta gacgagcagg acgtcgatga gcccgttgcg ggcggcggcc agggcccgct
     3541 ggaggtcctt gcgttcggtg gtggcgccgg aggcgtcgtc ggcgaaccgc agggcgacga
     3601 tccagttggg ttgggagtcg acgtaggagc gcagccgttc ttcctgggcc tcgatcgtgt
     3661 agggctggtt ctcgtcgtca gtggagcgac gcaggtagat cccgacccgg acgatctcgg
     3721 gttgcgcggc gacggcctgc ttggtgcgtt tcgcggtagt acggcgcgca gtcgagcgcg
     3781 gcatggtgag gtacccttcc ttcccgaatg gggtgtgctg agacgccagg gctccggcac
     3841 gttcgcgtta tgaccggctc gtccgcgcgc cgacgggacg gcctggatgt ccgtatcgtc
     3901 agggaaagcc gtgcaggtcg agcgcggcgg tggcggtctt gcaggcccgg cgcccggccg
     3961 gaacgtagcg gtggcccgcg gcgcggaccg cgtgcgcgac agtggcgcgg aagatcgcga
     4021 ggttgaccgg gccgcggcgg gtccggctcc ggctcgcgtc ctcaccgaaa gtgacgtcac
     4081 ggacgtggtg ctgacggttc tcgatgatcc actggccgcg ggcggcgtcg gcgaggaacc
     4141 cggccgaggc ctgctcgaag gccagatccg tgatgccgta gaccgtctcc cggctgggtt
     4201 tcctgccctt ctcccggcgc cagcgctgga tccggacggc ctggcgggcg tgcgggaact
     4261 cggcgtgctc gacggtcgcg gccttcagcg tgcgggtctc gtcacggccg tggccatggt
     4321 cgtgggtggt gtcggcgacc gggacgtccg cccacggcaa cgcggccagg aacgcgcgca
     4381 gcgttggctg gttgcccttc acgaccgcaa ggtaatgggc cttcttgtcg gtgaccagcc
     4441 agtcgagatg gtcgcgcacg gtatgcagag cgtcgaaggt caacaggtcg caggcaaggt
     4501 cgaggggctc gaggacaggg cggaacgcct tcgtctcatt gctcttcgag tccacctcgt
     4561 gctggttgac cagccggccg gtcgcctggt cggcgacccc gaccagttgg acctgccgcc
     4621 cgtcggcgcg cttcgcgccg cggctggtct tcccatccag tgcgtagacc gcccgcaccg
     4681 cttctcccgc cgcctcgggt gacgccggct tcggcggggc cgggtcggcc agcggcggat
     4741 cgagcagtgc gcgggcgagc cgcgcgtcgt cggtgtcgtt gaggaaccgg cggatcgtcg
     4801 actcgctcgg cagccggtag ccgtcaaacg ggtcgtacgg cagccgcagc cggcgccgtt
     4861 cctcctccgt ggtgccggcg agccattcga tcacggcggt gacccggtca tggcccgccg
     4921 cggtcagcgc gcacagccac accgccgcca gcaccgccag cgggtagacc cgcccacgtc
     4981 ggccccggtg ctcgcccatc gcgtgcagcc gctgccagat tccctcacgc gacaccgcgc
     5041 cggctcccac cacaccggcc gcgtcacgcg acaatgcccc cacaggcacg tgcgctcccg
     5101 gaccacgaag acgttagaca cctccgtgat ctacaggcgc cgtgcctgtc ttcttctcag
     5161 cgacgcgtga cctggccgtg tccgcccgcc gacccccgcg cccgcccgat cagggcatac
     5221 cgggacccca ccagccaact ccgggcggac cgggacctca gctgacagaa ccggccaggg
     5281 caccgcccag caggccagaa caacgaacac ctggatcgat cacgcgatca gcgccaccca
     5341 ggacgcacgg ccacgatcac accaaagcgc gaacgtgccg gagccctgct ggctctggtc
     5401 cgcctgtccg agcaaagcca ggattacagg tgtcgctgtc gcgctgcccc ggttggccag
     5461 atgacctgga cggcgcggtc gtttgcttgg gcacgagcga cgacggcggc tgtgccaccc
     5521 tggtcggcgg cggcctggcc gtcccagacc gcgatgagta gatcgacggt gtcgaggagc
     5581 gcctcgttcg ccgcctcgta cgcggcccga tcggagacct cgtgcggcag gacccgcacg
     5641 gtggcagccc ggcggacgag gtcgtcgaac agaggggcgt ggtcgggttt gaccttcctt
     5701 gcgcggtagt cggcggcagg gatgatcact tcgagtgtgc cgccgatgtc caggacgacg
     5761 tcggcgaaga tgctgtcgga gccggccgcg atgcagctga cgccggtcag gtctggcgcg
     5821 tacggcatga gagccgcggt gagagcggcc cggacgaggg ggacggtcgc gggggtgagg
     5881 tccatgtggc cggtgacgcc gatgcgggtc aagtcctgac cttcctcacg tttcatatcc
     5941 gggccgccgt gtcttcggcg cgaagcatgg gtttgatcct cccgcacagc tcggcgatgg
     6001 ggcgggcgga tgtcctggtc tcggcgtgcc ggtagaactg gccgagtttg acccggacgc
     6061 ggctggaccg ggtctgctcg accgtcgtca cggcggcgtg acccagccgt gctgcttcgt
     6121 cgaactcgcc ctgcaccagt ctgatctcgg cgtgcccgag ctgatcaaga gcggtactgc
     6181 ggacgctgcc gacgccccga gcccggacgg cctggctcaa ccaggtggct gcctcgtcgg
     6241 catactcggg cgcctggtgc gcgacgtcga ggagacgacc tccggtgacg ccggccagtt
     6301 ccgcctggtc gaagtaggag atccagtgcg gttcaacgcc cgggtcgacg tcgcggagag
     6361 cgtcctgcgc ccggcctgtc acgcgccgga aggcggagag tcgaccttgc tgggcgtagg
     6421 cccatgcctc gcgcgtgaac agcatcgcac gcaccgccgg agtcgcccga gcaccagcga
     6481 cgtcctgcgc gaggcggacg agctcaagtc cttcggtcgt ccggccgaga tagaactgct
     6541 gccgcgccat gccagcgagg atgttcgcgc agaacacagg atcgtcagcc gccttggccg
     6601 atcgaagagc gagcaggtaa taacgctgag cgatcccccc ctggccccga gtcccaggac
     6661 atcgtcgcgg cggtctcagc aagatcggcc atcacgccgt gcagccgccg ggtcagattc
     6721 tgcggatgcg agaagtcgcg aagctcatcc gcgatctcag cgagctgacc cacgaccgct
     6781 ttccgtcgaa ggccaccgcc gaactggttg tcccaggccc gaaaggttcg cgcggccagc
     6841 tcgatctgct cgatctcctc atcgccgacg cctgcggtgc gacgctgccc ggcgggcggc
     6901 tcgatggcat gtagccagcg ctccgccccc tcaagcagag cagcgccgac gatcacgtcc
     6961 gccatcgcgc gagccgcctc gcggcgatca agggagagat catctctggc gatcttattc
     7021 accgcctctg tcgtcgatac cgtttcccat cccatgaaat ctgtcgttgc ctcgggaagg
     7081 cggccgatgg gactcgtgca cagttccacc agcgatcgag tttcccgggc ggtgggctcc
     7141 gccatggcgc cggcatcggt tctgtcgctc tggcgcctcg tctgtcccga cagttccacc
     7201 ggctgcggcc gtgcggtttt cgacgtcttg tcgatgagga gcaggtcggc ggggtcgaaa
     7261 tgttcgcggt cgtcaaggtc gatcaggttg tggatgctgg tgtcgtagac ctcggcgagc
     7321 agggcgagga tctggggggt gggccggcgg cggttgttcg gcaacggcca gttctccagt
     7381 tccgacagct tcggtgcggt catgggcgcg gcgccgtggg ggtcgaggcc gacgtggacg
     7441 gcgtgggtgt tgatgtggtt ggcggcctgc tgctgggtcc agccgtgcgc gacgcggtgg
     7501 gcagcgcgtg ggcgcagccg gtagcgccgg ccgaactcga tcgcgatctc gtcgtggctc
     7561 atcccgaccg cgcgcatccg cgcccgcaac tcgtcctgtt caacacgctg actgggtctg
     7621 ggcatgagac agcctccttc catcgggact tgggcgccgc cgtccagaat gatgcgcggg
     7681 tcgaggcgca gcagcgtcgt gggataggcg catggtcacg atgggtcctc tggcgcggag
     7741 atctcaccgg cgggccgacg cgctggcagg gaattgagaa cgggacgcca ggcgaaggag
     7801 gtggtgccgt cggggggccc gatcgcgttg gtcggcagga cggtgaagcc gtaggtggtc
     7861 aggtcgcgta gggctcgggc gaaggccggg tgggcggcga gggtgggttt gacatagggg
     7921 gcgatgacga cgggcagccc gagcccgatt gtttcgttca tgacgccgag cgccgcgttg
     7981 tcgttgatcc cggcggcgca cttgttgatc gtgttgaagg tcgcagggac aaccaccacg
     8041 gcgtccgcgg gcggcaggcg aggctcgtcc ggccgccggg gccgtgagcg gaccgggtga
     8101 ccggtcaact cttccagagc gtgcacgtcc agccaggtcg tggcgaccgg cgtcggcaca
     8161 aggcagactg cccaaccatc cgtgtggacg tggcggatca gctcgtcgac ctgcgcggcg
     8221 ggtggggccg cgcagaccac cagatgcagc attggtcgtc cactgatcac gttgcgactc
     8281 cggcctgctc cgcgacactc cgtaggaccg agacggtgga gccgcgggca cggccgagca
     8341 gtgtcgccag cacagcccga gctgtcggat caaccctcag cagctgcggc gcccggcggg
     8401 cgacgtcaag gatgtgcacc gccgcgatgg catcctcgcc caggcgggca tgcccgccgg
     8461 aaagatctac gtgcagacgt gcgcgcctgc cggccagcgg gggtggcagc agacgtgtgt
     8521 cgatctgctc gccgacgccg accgcctctg tcggatcgtc cagtaccagg gtggcggtaa
     8581 gggtgtggat cgcgacgttc gtcggcccga acgccgacca cagccggttg ttgtcccggc
     8641 caagcgcgtc agcctgctcg gccgcggcgg tgagccggcg gcggccttcc gtccgttcgc
     8701 ctcggcggat cgaggtcatt gccgagagca gaagaagagc gccccgcgcg gacgagaggt
     8761 cgcggtggtc ctcgtcgcct ggtcgctggt tcagggcgtc gagggcgctg accgcgaccc
     8821 gttcggcgtc ggccagccgt cccgtgtcgt ggaagacgca ggcgatctgt ctgcgcgctg
     8881 tcgccagtag cgctggcgcg tcggcagcga gcgccgcgtg ttggccacgg tctgcggcca
     8941 gccaggcgag atcgtggtcg ccggtcttgg tcgcgagctt ggcggcagcg atgtacgcga
     9001 cggcctgcgt ccgccggacc gcgcggtggt tcacgccagt cggcggatcg accgtgagtg
     9061 tctcgatgcc ccgcaccacc gcggggagaa gtctcgccgt gcctgcgtag tcggcccgct
     9121 ggtagcggtc gtggcactcc cgcgcgcgag cgtcaaggtc ggcagggccc gcgaatgagg
     9181 ccgggtcggg atcggtggac cactccgccg gtgccgtgat ggcttctcgc agatcagcga
     9241 gaagatcgca tgcggccggg aacacggtcg accggacgct cacggacggg gacggcgcgg
     9301 ccggctgtcg gggcagcacc acggcaacgc ccaaggctga cgccgcgagc aggaactgct
     9361 gccgattcgg cgcatccacc atcggcgtga cctccgagct tgccgactgc gcttgtggga
     9421 gcgaaccgat agcgctcgcc ggcacggccc tctcacggat cgtggtgatg agcagcagat
     9481 cagcaggagg catctgttcg cggtcgtcaa ggtcgatcag gttgtggatg ctggtgtcgt
     9541 agacctcggc gagcagggcg aggatctggg gggtgggccg gcggcggttg ttcggcaacg
     9601 gccagttctc cagctccgac agcttcgggc cggtcatggg tgcggcgccg tccgggtcga
     9661 ggccgacgcg ggcggcgtgg gtgttgatgt ggttggcggc ctgcgtctgg gtccagccgc
     9721 gggcgtggcg gtgggcggca cggggccgca acttgtagcg gcgggcgaac tcgacagcga
     9781 tctcgtcgtg ggacataccc accgcgcgca tccgggcccg caactcctcc tgctccaccc
     9841 gccggctgag cttgctcatg acgccaccgc acatcccctc cggacccgaa tattgatctc
     9901 tgtgccctct gcgttgtaac gggaactgtt acaccgtagt caaacggtcg cgggtagaac
     9961 aatgatttgg ctcatcgggt atccgttgat gttgcggatg ttatccgggt gcattgtcga
    10021 agacggcttc cttcgcggca cgcgcgagcg tggcctgggt ggttgctgcg agtccgattc
    10081 ggttccagtg gaagattaca tgtagtgcga ttgtcgagcg tattccccgg gtgagttggc
    10141 cgttttctcg cagggttcgg agcgctcgtc ctgtctcgtg gaacgctgtg agccagtcgc
    10201 cgtcggtgag gtctgcgcgg gcgtcgccga ggaggagacg acgtacgtcc caggtgaagg
    10261 acgcccatat ctgcgggtcg ggtggtactc cggcgagggc ggcgcgctgc tcagctacgc
    10321 gtgcccatac gtcgccttgc tcgttgatgt ccagtcccgc ggcccgcatg agcttggtac
    10381 acagcaggag ggagcgttcc cgccggtcgg tgcagccgtc gccaagggcg gagagcagac
    10441 ggcggctgtc cgcgtggaac agcgagtggg ccaggtccat gctggccggc ccgccgaagg
    10501 cgtggacctc aggttcgtag atgtcgtcgg tccagatgac gcctttcgtg agcaggggat
    10561 ggagcgggtc ggtggcgtcg ctgtgacggc cgcccgcggt gtcagtgaga aggtagcgga
    10621 tacgccacgg gcctttgcgg atgaaccacc aggaggtgat caggccgcct gcctcggccg
    10681 gcgggaggat ttcggtcagg tgggcgatgg cttgacgctc ccgctcagcg gggtcctcgg
    10741 cggggtaggt gatgttcacc tgcttccagg gagtctcttc cacggcgggc ctttccatca
    10801 gcggagcagg agacaggcgt cccacgaggt tgtcgtggtc gcggtggtag ccaggtctgc
    10861 gccggccgat ccgaccagga aacccggggg ttcgtcgtcc tcggcagcgg cgggctggtg
    10921 caggagttgc ggctgtgtga gggagatcgg ggtgagggcg tcggcggcga tgttgcgggc
    10981 ggttgcgagg agcccgccgg tcccgtggca caggctccgg tcggtgaggc ggctcagctg
    11041 cgtcgggtcg ttcagacagt cgaggaaggc ggtctcggcg cggcgttggc gggcgggttc
    11101 gtgcagggca cgggcggcga gttgctggga gcgggcaatg ccgggagttc cgtaacacca
    11161 ggaaggtctg agcgggccca gttggctggt ggtgccgcgg tcaaggtcgg tcagtgtgac
    11221 gatctgcggc caccaggagc cgccgccagg cttctgctgc tcccaggcgt ccagccacca
    11281 gcagatccgg gtgatcgcct ccgtttgccc gtcaaccttg atgccatcgc tgagtgggcg
    11341 ttctgcacgc tttcgccggg tctcagcttg agttgatctc tggggtgcgg agttgatcgt
    11401 cttgcgttcg ccggctggcg cgttctgctg gaagacatgg cagaacgcaa gccgtacccc
    11461 agtgacctgt ccgatgaggc gtgggacctg atccgcccgg tcctcaccgc gtggaaggcc
    11521 cggcatccct cggctagcgg gcacgagggt ggctacgaca tgcgggagat cgtgaacgcg
    11581 gtcctctacc aggcccggac cggctgccag tggcgctacc tgccccacga cctgcccccg
    11641 acgtccgcgg tgtactacta cttcggccag tggcgcgacg acggcaccac cgagacgatc
    11701 cacgacctgc tgcgctggct ggtccgtgag caccaccgca ggaaagccga cccgagcgcg
    11761 gtcgtgctgg actcccagac cgtccggtcc tccaccaacg ccccgaaggg cacgaccggc
    11821 ctggacccgg gaaagaaaag cccgggccgt aaacgcggga tcgccgtcga cacgttggga
    11881 ctgctcatcg ccgtggtcgt ggtcgcggcc agcgtgcacg acaacaccat cggcaccgcc
    11941 ctgctggacc gggtcgccgc cgccgccccg ccggtgcgca aggcgtgggt ggacgccggg
    12001 ttcaagacca ccgtcgtcga gcacggcgcc ggtctgggca tcgatgtcga ggtcgtcgga
    12061 cgcgagccgg gagcgcgggg gttcaccccg ctcccgaagc ggtggcgggt tgagcagacc
    12121 ctgggcacgt tgatgctgca ccggcggctg gcccgggact acgaggcgaa accggccagc
    12181 gcggtagcga tgatccactg gtcgatggtg gaggtgatgg cccgccggct gaccggggcg
    12241 gccaccccga cctggcgtga cccgccggtc tgaccggcgg gagtgtcggg aatgacgagc
    12301 ggagtgccgg tgcgggaggt gctggaacag atcgaggctc ggcgggcccg cgccgggcgg
    12361 gccgtcgagg agctgcggga ggagatcgcc cggctcaccg ggcagctcgc cgccgctgaa
    12421 cgtgccctgg aacggttgga gatcacccgg gagacggtgc tggacctggc cgcggagaac
    12481 gacgccgcac cggccgagcc gctgccgccg gggtatcggg aggtgctggc cgtgttcacc
    12541 cggggcggga acgggctgca cgccaaggac gtgtgccggg cgctgggtgg cggcaccgag
    12601 ccccggcatg tcgagagcat gcgggcccgg ctgaaacggc tggtagagcg gggtgttctc
    12661 accgagcccg atcccggcct gttcgtcctg ccccggcccg acccaccggc caccccagag
    12721 atcaactcaa gctgaggccc gacgaaagcg tgcagaacgc ccactcaggg ccggctcgtc
    12781 ggcacgcagg cggactggcg ggcggtcgcc gggcggctct ggcaccgatc taagatcgac
    12841 caccccggga acgtcgctgc ctgcgatagc aagcacggcg cggaccatgc cagacagcac
    12901 agccgggtcc agctgctccg ccagtgctgc gtctgtgatg acgacagggt tgtccagtcg
    12961 acgtagcaac gcccggtgaa cgtccgccga gaaatgcgaa gagatcagta ctgggactgc
    13021 gccaacgcgc gccacggcca gcgctgccag cacgtacgta ttcggaagtc ccgttgttga
    13081 tcttttgggg tgacggcctt cggggctggg tgtggcctga tggtcgtggt gggtgatgtt
    13141 ctgccggtcg gggtggtttg ctgcggtgcg tgacggttgt cgagtcgggg gcgggcgctg
    13201 ccgcgagcgg tgaggttgcc gagggcgcgg cgctgctggc ggagaacgcc tggctgcggg
    13261 cccgggtcgc ggagctgttg acggacatcg ccgggctggt cgcgcgggag gcgacgcgtg
    13321 aggccgaggt ggtggagctg cgtctccagc tcgaggcgtt gcaggcggag ctggcgacgt
    13381 tgcggcggat gctgttcggc cggtcgtcgg aacgggagtg cggcgggtcg ccggccgtgg
    13441 gttcgccgga tggcggggac ggttgtggcg acggggcgcg gggcgaggcc gccgggtcgg
    13501 caggccggcg gcgggggccg ggcgcgcgct cgggccggcg gagctacgac catctgtccc
    13561 gcgacgaggt cgactgcgac ttcgagggcg ggggctatgg ctgcctgtcg tgtgggcagc
    13621 cgttcacgcc gtggggcgag catgtcgtcg agcagctcga ctggctggtg acggtgcggg
    13681 ttcgggtgtc gaggcggcgc cggtatcggc ggggctgccg ctgtggcggg tcgttgacgg
    13741 tgaccgcgcc gggaccgtcg aaggcgatcg ggaagggcct gttcacgcac cggttcctcg
    13801 cgatgctgat cgtggagcgc tatgtcgcgg gccgttcgca gaactcgctg gtcaccgggt
    13861 tggcccggca cggcgcccag ctctcgccgg cgacgctgac cggggcgtgc gcccaggtcg
    13921 cgggcctgct cgccccactc gccgagcaga tcgtcgggcg gtcgcggggg tcgtggcacc
    13981 tgcacgccga cgagacgacc tggcgggtgt tcaccccgac cggcggcggc gggccggccc
    14041 gctggtggct gtgggtgttc ctggggccgg acagcgtctg tttcgtgatg gacgcgaccc
    14101 gctcgacggc ggtgctcgcc gaacacgtcg gcctcgaccc ggacagcggc cagctgaccg
    14161 acgacgccga cggcggaccg cgccgcctcg tgctgtcgtc ggacttctac accgtgtacg
    14221 tctccgccgg ccgccgcgcc gatggcctgg tcaacctgta ctgctgggcg cacgcgcggc
    14281 ggtacttcgt gcgggccggc gacgcgaacc ccgcccagct cgggatctgg gcccgccagt
    14341 gggtcgagcg gatccgcgcg ctctacaccg cgcacggcga gctcgccgcc gcctggcaca
    14401 ccgccgccgc ggccccgtcg ccggccaccg agaagcggct cgccgccgcg tacgccggct
    14461 gggacaccgc gatcaccgtg atcgacacgg ttcgccgcga gcagacggcc tcgcccggcc
    14521 tgcaggaacc cgcgcgcaag gcgctcgcga ccctggaccg ggaatgggac gggctggtcg
    14581 cccaccgcga ctaccccatg atcggcatgg acaacaaccc ggcggaaagg gcgatcaggg
    14641 gcccggtcgt gacccggcgc aacgccggcg gctcccgcac cgaggacacc gcccgccacg
    14701 ccgccacgat cttcacggtc accgcgaccg ccgcgatgca caacctgaac ctgctgacct
    14761 acctggagaa ctacctcgac gcctgcggcc gggccggcgg caagccgccg accggcgccg
    14821 acctcgaccg gttcctgccc tgggccgcca gccccgagga cctcaccacc tggcaacagc
    14881 ctcccggctg accccgaccc ccgagacccc agcggagtgc cccacggtca cgccgcccac
    14941 gatcatgccc caacgggatt tccgaatacg tacgccagca ccacatcgaa cccgttcgtc
    15001 atgatgacgg ccacctgatc ggccggacgg accccagcag cgtacaaccg gtgtgccgtt
    15061 ttatcgacaa ctcccgccaa ctcggcgacg gtgaattccc tccgatcgcg tccaccgtcg
    15121 accaggttca gtggatggtt tgtcgtgaca gtcattcctg gattgtcgtc ggccgcctcg
    15181 gcgagcagat cgccaagata gaagggtgct gcggctggtg ctcctgggag gcttcccata
    15241 cctgtccaat ctcccgcaat gttttacgtc cgaggctcgt tattagtcca catccctgag
    15301 gcttcgaagg tcttatgcgg gacacagggg ggtcccaaaa aagcgctctt cggctgcgga
    15361 gtaaagctct gcaaggatgc ccgtctgggt gcgctcgccc ctgtagtgat ctccaaagcg
    15421 gtcgcgatag acggcgaacc agtcgggtcg gctatgcaaa aagagaatgt cgtgtactga
    15481 cattcttcgt attgcgaata gcgggactgg tgagacgttg acgtgaaaat cttgattgcg
    15541 tgccgatggt tccgtgcagg agccgtggaa ctggccgatc atcaacccca gagacaccgc
    15601 ctcgctcttg actatggaat gcacctggtc tatgagaggc cagtcctgtt cgcccatgtc
    15661 agggaacgcg agcacaagag ccggcaagga aagttcaggc tgccagaaca acgcgggaaa
    15721 caggcgtatc gcctcgcgga cccggtcctc cagccaactg gcgaagatcg gcttcggtag
    15781 atccagtgtc catagtcgga tctggtcgcc gtcgagggcg gggcgtacat aggggcagac
    15841 ggcccccagg cgtccgagca tggggtgcgg tcgtgcgagg tagctgcgaa accaactgtt
    15901 gacggtcttc tccgccgtgt ggtcgtcaga catcgactct ccggatttga cgctgccagg
    15961 caggcgcgac caacggtcgg cacctcgccg tagcgggacg gcatccgctc ccccggcgac
    16021 gcggtcggac caggccgcac aggcgcgcgt gcacttgtgc gcagggaccg atgtatgccg
    16081 cgttccagcg acccctcacc gcgaggtgga gcggcagact ccatgatcag aaagctctta
    16141 gcggacatct cagataggaa aagactgtaa tagcacccgc gtgggattgc aaccacatgc
    16201 agcgatcggg tcgcattcgg ctgcatgccc caccttgatg gtcaccatgc gtaagcatgt
    16261 cataaacggt gagatccgga gcgccggcgg gctcgcgcta ccgccacccg atccgacggc
    16321 gccatgcatc gcgccctagc tgcgacctga cccgcggcgc gtctacccag gtgaagcagt
    16381 attccggtga tatactatcc ggaatatgag gctcagtcag ggaatcgagt gggcgttgca
    16441 ctgttgccat gccctcgcgg aggcgccgga tggaagctcg ctgcccgtgc agcagctcgc
    16501 tgcgctgcac ggtggtaacc cggcctacct ggccaaacac ctccaggcgc tgtcgaaggc
    16561 cggggtggtc gtgtcggtcc tcggcccacg cgggggctat cgactcggcc gtcccgcgga
    16621 ccagatccgg ctcctcgacg tggtcgacgc gatcgagggc tccagcccgg tgttcctgtg
    16681 caccgagatc cgccagcgag ggccggccgc gttgccaccg gcgaactacc gagcgccctg
    16741 cgcgatcgcg gcggcggtgt cgtccgcgga ggacgcgtgg cggcaagctt tggcgtcgac
    16801 caccatcgcc gacatcgtca ccgcatcgcg ccggcaggca cccgaggccg ttaccgctac
    16861 cgctcgctgg ctacgcgaga ccgtcgacgc gagaagccgg ggccaggcag acgagcagaa
    16921 caggaaggcg gacgggtgac gggccacggc gcggcccggc gagacgtacc agagcccagg
    16981 gtgactcgtc cccctgtgga ggcttcatcc gcgtcgacgc gcgaggtccg actcgacggg
    17041 gccccgccga actcgacaga ccacggtgat gcgccctgtc cccggcccga gacgcgcgac
    17101 cggcagcggt ggggcgcgct gatcaccggc tggctggcac tgttcgtcat cgggaccgat
    17161 ctgttcgtcg tctcgcccct gctgccgatc tggcgctccc ggttcgacgt gtcactgcgc
    17221 acggccggac tgacggtgac ggtcttcgcc ctggcctacg tcgtcgcggc acccgcgtgg
    17281 ggtcggcgag cggtgaaggt atcgccgccc gcggtgctgg ttctggccct gtccggcttt
    17341 gcggtgtgca atgtgttgac cgccctcgcc ccgaacttct ggacgttgct ggccgctcgg
    17401 gtcggcaccg gtctgttcat ctccggcgcc acggccaccg tgttcacact ggtcgcaagc
    17461 agcgccccca acgggcgacg ggcgtcgtgg ctggggatcg ccacctcagg gctgctgtcc
    17521 gcgctgtggg ccggagcccc tctcggtggc ctggtcgcac ggcacaccag ctggcgggcg
    17581 gtgttcgtca tcctggccgc attcgccgtc ctcattctgg ttgctgcccg cagaatctgg
    17641 ccggacacac aggcagcccg cgccgccgct gcgcccgcca gccgcagtgc cgcgtggcgg
    17701 gcccgcgccg tcgcgccgac cgcctgctgg gcggcagccg tctacggcct gtacacctat
    17761 ctgtcggctg gcctcggtga ccggcccgga tggtccaccg cctggctgaa cgcatcgttg
    17821 atcgtgtacg ggttgtgcgc tgtcgccgcc acgttcctcg gcggtcggat cgcagaccgc
    17881 cacggcgccg cccgcaccac ctggacggca ctcctgctgc tcgccgccgc cgacgtcgcg
    17941 ttctccgcaa gtctctccag cgcggcggtc accacctgcc ttgcgatcgc gttgctcgcg
    18001 ttcgccgcct acaccgcctt tcccgccaaa caggctcagc tcgtctccga ccatcccgcc
    18061 gactccgccc agctgatgtc ctggaaccag agcgccatgt acctggggat caccctcggc
    18121 tctctggccg gcggacgcat cgccgacggc cacttccgcg cgctgccact cgcatgcgcg
    18181 gcggtcgcca tcctcggcgc caccacacag gtatccaccg tccgccgccg gactccggcc
    18241 ggtcatgcag cggatagtga ccggtggtga cggttgattc tggagcgccg gtcccggacc
    18301 tccggactcc ggaagcgccg aattccggac gtcgaaagtg ggcccgacta cggtcaacgc
    18361 cgccacttcg tggcgagctc ccgatcccag gccgacctgg gggagtggcc agcgtgagtg
    18421 acgtagacgc gccaagcagt cgtgagcatg tcagtgaccc agtagcggcc cagggtgtcc
    18481 tcgtgtaggt cgccgatggc atcggcgacc gcggagcgca gactgtccgc gtcgtagtcg
    18541 aagaacatga tcagatagct ggcgagttcg gcggttgcgc cacgttcccc ctcagtgggc
    18601 gttctgcacg ctttcgtcgg gcctcagctt gagttgatct ctggggtggc cggtgggtcg
    18661 ggccggggca ggacgaacag gccgggatcg ggctcggtga gaacaccccg ctctaccagc
    18721 cgtttcagcc gggcccgcat gctctcgaca tgccggggct cggtgccgcc acccagcgcc
    18781 cggcacacgt ccttggcgtg cagcccgttc ccgccccggg tgaacacggc cagcacctcc
    18841 cgataccccg gcggcagcgg ctcggccggt gcggcgtcgt tctcggcggc caggtccagc
    18901 accgtctccc gggtgatctc caaccgttcc agggcacgtt cagcggcggc gagctgcccg
    18961 gtgagccggg cgatctcctc ccgcagctcc tcgacggccc gcccggcgcg ggcccgccga
    19021 gcctcgatct gttccagcac ctcccgcacc ggcactccgc tcgtcattcc cgacactccc
    19081 gccggtcaga ccggcgggtc acgccaggtc ggggtggccg ccccggtcag ccggcgggcc
    19141 atcacctcca ccatcgacca gtggatcatc gctaccgcgc tggccggttt cgcctcgtag
    19201 tcccgggcca gccgccggtg cagcatcaac gtgcccaggg tctgctcaac ccgccaccgc
    19261 ttcgggagcg gggtgaaccc ccgcgctccc ggctcgcgtc cgacgacctc gacatcgatg
    19321 cccagaccgg cgccgtgctc gacgacggtg gtcttgaacc cggcgtccac ccacgccttg
    19381 cgcaccggcg gggcggcggc ggcgacccgg tccagcaggg cggtgccgat ggtgttgtcg
    19441 tgcacgctgg ccgcgaccac gaccacggcg atgagcagtc ccaacgtgtc gacggcgatc
    19501 ccgcgtttac ggcccgggct tttctttccc gggtccaggc cggtcgtgcc cttcggggcg
    19561 ttggtggagg accggacggt ctgggagtcc agcacgaccg cgctcgggtc ggctttcctg
    19621 cggtggtgct cacggaccag ccagcgcagc aggtcgtgga tcgtctcggt ggtgccgtcg
    19681 tcgcgccact ggccgaagta gtagtacacc gcggacgtcg ggggcaggtc gtggggcagg
    19741 tagcgccact ggcagccggt ccgggcctgg tagaggaccg cgttcacgat ctcccgcatg
    19801 tcgtagccac cctcgtgccc gctagccgag ggatgccggg ccttccacgc ggtgaggacc
    19861 gggcggatca ggtcccacgc ctcatcggac aggtcactgg ggtacggctt gcgttctgcc
    19921 atgtcttcca gcagaacgcg ccagccggcg aacgcaagac gatcaactcc gcaccccaga
    19981 gatcaactca agctgagacc cggcgaaagc gtgcagaacg cccactgagg acccgtgtga
    20041 tgtcggtcag catgcggcgg ggatgacgta gcggtgccag gacactgaag ccgatgaccg
    20101 cgtcgaagct ggcgtcgggc agcggcagtg gccgttccgc gagatcccat accgatcccc
    20161 atgtctggct gttctccggg gtcggccgga tctggctcag tgccgcccgg gtcggggcca
    20221 gggtcgtgac gctgccgccg ggcacgacgg ccgcgagcgc cgcgggcgtc agtctggcgc
    20281 ccaggctgag gtccagcagg tcctgtccgg tacgggcggc ggcgccgtct agcacggtag
    20341 ctgctagggc ctgttctgag tccggatcac aatcggggtg ttcatccttc gttcgggtgc
    20401 ttcggctggt agcacggctg tatgacgcgt ggtgatctga ccgatggtga atgggagttg
    20461 atcgagccgc acctcccgct gggggcgtcc ggaccgatcc ctgacctgcg cagctatttc
    20521 aacgcggtga tgtggaggtt ccgtaccggc agcccctggc gggacgtgcc gaacagctac
    20581 ggctcctggt cgacgatcta cgaccggttc cgcatgtggg cgcgggacgg ggtcttccag
    20641 accctcatgg acgcaatgat caccgaggcg gcggcgcgcg acgatgtcga tctcagcctg
    20701 gtcagcgtgg actccaccat cgcccgcgcg catcaccacg cggcgggcat ggcggtcgac
    20761 ccggacctcc tggaggacat agagaaggcc ctgacggagg aaaaggggct tcagaaaccg
    20821 ggcaaaacga ctccgtaacc gaggcgcccg agggcggaga ggaagccgaa cgggcacggc
    20881 gccgcgcggt acgccgacgc cgcaaggccc ggctgaaagc cgccgaactg ggacgctccc
    20941 ggggcgggct gaccagcaag gtgcacctcg cgaccgaccg gcgctgccgc ccactgtcca
    21001 tcatcctcac ccccggacag gccgcggaca gcccgcgttt cctcccggtc cttaagaaga
    21061 tcaaggtgcg tggaccggtc ggccgcccca ggacccggcc ggacgcggtc gccggcgaca
    21121 aggcgtactc ctcccgcgcc aaccgcgccc acctgcgcac acggaagatc caggcggtga
    21181 tcccggagaa ggccgaccag acggccaacc gtaagaagcg cggcagcgcc ggaggccgcc
    21241 cggtcagcca cgacgccacg ctctacaaag accgcaacac cgtggaacgc ggcatcaaca
    21301 agatcaagga atggcggggt ctggccaccc gcta
//
