LOCUS       NC_007777              27177 bp    DNA     circular CON 05-SEP-2024
DEFINITION  Frankia casuarinae, complete sequence.
ACCESSION   NC_007777
VERSION     NC_007777.1
KEYWORDS    RefSeq.
SOURCE      Frankia casuarinae
  ORGANISM  Frankia casuarinae
            Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
            Frankia.
REFERENCE   1  (bases 1 to 5433628)
  AUTHORS   Normand,P., Lapierre,P., Tisa,L.S., Gogarten,J.P., Alloisio,N.,
            Bagnarol,E., Bassi,C.A., Berry,A.M., Bickhart,D.M., Choisne,N.,
            Couloux,A., Cournoyer,B., Cruveiller,S., Daubin,V., Demange,N.,
            Francino,M.P., Goltsman,E., Huang,Y., Kopp,O.R., Labarre,L.,
            Lapidus,A., Lavire,C., Marechal,J., Martinez,M., Mastronunzio,J.E.,
            Mullin,B.C., Niemann,J., Pujic,P., Rawnsley,T., Rouy,Z.,
            Schenowitz,C., Sellstedt,A., Tavares,F., Tomkins,J.P., Vallenet,D.,
            Valverde,C., Wall,L.G., Wang,Y., Medigue,C. and Benson,D.R.
  TITLE     Genome characteristics of facultatively symbiotic Frankia sp.
            strains reflect host range and host plant biogeography
  JOURNAL   Genome Res 17 (1), 7-15 (2007)
   PUBMED   17151343
REFERENCE   2  (bases 1 to 5433628)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Goltsman,E.,
            Martinez,M., Schmutz,J., Larimer,F., Land,M., Kyrpides,N.,
            Lykidis,A., Francino,P., Benson,D.R., Huang,Y., Mastronunzio,J.,
            Bickhart,D., Niemann,J., Rawnsley,T., Tisa,L.S. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2006) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000013345.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 02:41:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,755
            CDSs (total)                      :: 4,702
            Genes (coding)                    :: 4,516
            CDSs (with protein)               :: 4,516
            Genes (RNA)                       :: 53
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 53 of 186
            Pseudo Genes (incomplete)         :: 162 of 186
            Pseudo Genes (internal stop)      :: 10 of 186
            Pseudo Genes (multiple problems)  :: 37 of 186
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:46:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1652353
            Orig. end                         :: 1679530
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000249.1.
            URL -- http://www.jgi.doe.gov
            Source DNA and bacteria available from Louis Tisa
            (lst@patia.unh.edu)
            Contact: Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27177
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..27177
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27177
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:17177](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..17177)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    1004..1017
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            1247..3490
                     /locus_tag="FRANCCI3_RS06915"
                     /old_locus_tag="Francci3_1377"
     CDS             1247..3490
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435819.1"
                     /locus_tag="FRANCCI3_RS06915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1377"
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_011435819.1"
                     /transl_table=11
                     /translation="MDAETVGAGLPAGGGLTPALSRADGGADEASRALSAARQASVRLA
                     HLARRMATPRMSQVPPELRDIVEAHRDYHPRADIGLLVHAYGVAERLHAGQMRRSGDPY
                     ISHPLAVTEVLAELGVDTTTLIAALLHDTVEDTGYTLDSVTQEFGAEVANLVDGVTKLD
                     KMRFGEAAEAETLRKLIVALARDYRVLVIKIADRLHNMRTLAFMSPPKQVKISRVTLEV
                     LAPLAHRLGVSVIKRELEDRAFAVLHPAEHARIAATVDEFTAAERAAGTVAALVARLRA
                     GLAGARIDGAVSIRVSHLFSIYKRAQERNRPVQDYTDLVRVLVLVDEVTDCYAALGVIH
                     ALWRPVPGRLRDFVATPKFNMYQSLHTTVTDGAGRSLDIQIRTPSMHRLAETGIVARPV
                     GPGADGARLEGLSWLHSLLDWQEEVDSDEFLESLSSDLDADEVLAFTPKGRMLALPARS
                     SPVDVAYAVHTDIGHRAIGARVNGRLVPLHTRLRNGDVVEILTSNLPGAGPSEDWLHFV
                     RTSRARVRIRRRLARQRRDTAAGAAEPGVTTTRSGSGGGARTAGGADGASSGLPSPTRP
                     IARRGMPSLAAVADDGVGGRVPARLARCCLPLPGDVVVGFATHGSTVSLHRRECMNATE
                     AGSDRERVAVATWSAPQAQIFPAEIAVEAFDRYGLLADITEVLSEISASVRAASTTTSD
                     DRVAHARFTIEVTGPEQLDKVLGAVRGVGGVYDCYRVCQTQGSSAHGAPAGDG"
     misc_feature    3720..3730
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            3837..4163
                     /gene="cutA"
                     /locus_tag="FRANCCI3_RS06920"
                     /old_locus_tag="Francci3_1378"
     CDS             3837..4163
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435820.1"
                     /locus_tag="FRANCCI3_RS06920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1378"
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="WP_011435820.1"
                     /transl_table=11
                     /translation="MGHLQVIVSIDSRESADRIGRILVEARLVACFQVIGPMSSTYRWK
                     GQIEQAEEWLCLAKTTTERFDELHERLVVLHPYENPEIIATPIVAGHADYLGWISAETA
                     PTVR"
     gene            complement(4156..5679)
                     /locus_tag="FRANCCI3_RS06925"
                     /old_locus_tag="Francci3_1379"
     CDS             complement(4156..5679)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435821.1"
                     /locus_tag="FRANCCI3_RS06925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1379"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_011435821.1"
                     /transl_table=11
                     /translation="MQLTTGPSAVPRAPVASAPTPEVSGGDRTPTTRTPNTRTPNTRLR
                     LSREERGWSQERLATEIRRFSVIHEGREAGVTGNMICKWEKGDKKPSLRYQRLLRALFG
                     RSSAELGFVDDEALPAAVGALRGGTGQGTAVAASMNLEQAACETGAAGTLVLHPGTDMI
                     DTNGIPVERRDFLRLFAAAGGVAVVPMNGVTDTPPWERLSAALRRRSTVTPELVNELGQ
                     LTAGLYGLEERVPARILIQRVTGHLSRLSQLLETTSRSPVRRELTSTAGETAALAGWLS
                     FDMNDLPAAVAYYRVAIEAAREADDHALWACVLGYESYQTASRGRHDQACALLGEAQRR
                     AATGSTVMTRAWLAAREAEEQAARGEGRAALAALDRAQDAFDRGESDGDRVWTQFFDRG
                     RLDGLKVTTYTRLRRPAAAYAAATEALRAAAPGATKKRSLLMSDIAEVHIQRREIEAAC
                     HFAAESLAIVLQTDFSLGLARIRRAREHLRPWQHTQAVREFDEQLRALT"
     misc_feature    complement(4990..4992)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5852..7657
                     /locus_tag="FRANCCI3_RS06930"
                     /old_locus_tag="Francci3_1380"
     CDS             5852..7657
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435822.1"
                     /locus_tag="FRANCCI3_RS06930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1380"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_011435822.1"
                     /transl_table=11
                     /translation="MRAGPLDRSPRPRRPVPPARPLRAWQRAALEIYRSRSSSGARDFM
                     AVATPGAGKTTFALQVAADLLTAGEISRITVVAPTEHLKRQWAVAAAEVGVDLDPDFRN
                     SAGATSSDYTGVAVTYAQVAAHPALHRARTAARRTLIVLDEIHHAGDALSWGEAIREAF
                     TPAARRLALTGTPFRSDVNPIPFVTYLPGPDGVMRSIADSSYGYAEALRDGVVRPVLFL
                     AYSGEMTWRTSAGAELSARLGEPLTNEQTAAAWRTALDPGGDWMPAVLASADTRLSQVR
                     AGGMPDAGGLVIATDHAAARAYAALLTRITGTSPVLILSDDPTASTKIDDFRRSADRWM
                     VAVRMVSEGVDVPRLAVGVYATSASTPLFFAQAVGRFVRGRGRGETASVFLPSVPSLLA
                     LAGEMEVQRDHALEKSPRDPDAFDDDALRDANRRKDIPDKPDTLFTALGSSAHLDRVIF
                     DGGEFGTPAAPGSIEEEDFLGLPGLLEPDQVAVLLRQREAAQQAAQQAATRRAAARAAD
                     SPVVPPAREGVQPAVEAATRPVHEVIGELRKELNRLVGAHFHRTGKPHGMIHAELRRTC
                     GGPPSGQATAAQLQARIDTIRRWAG"
     gene            complement(7666..8544)
                     /locus_tag="FRANCCI3_RS06935"
                     /old_locus_tag="Francci3_1381"
     CDS             complement(7666..8544)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435823.1"
                     /locus_tag="FRANCCI3_RS06935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1381"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_011435823.1"
                     /transl_table=11
                     /translation="MASSKERRQRELAEARAARQAQRRRLAHRRRQQRLAIVAGFIAIV
                     VAASTIAAILLTGKDDQPDVAAAGAATTPTATAPTATAPTPSAAPRQTSRVGQCTYTSN
                     GEAPARGATLPAAAATVDTSPATMVIITDAGTITAALDAQKAPCTVHALRTLADARYFD
                     GTTCHRQTGGADAGISVLQCGDPTGTGNGGPGYGYANENTQGVTYDRGVLAMAHSQLPD
                     SNGSQFFINYQNPTPQGAAALAGNYTVFGKITKGLDVLDKLTGPGVEGGGSDGAPASKP
                     KILSITITQGG"
     gene            8766..10028
                     /gene="serS"
                     /locus_tag="FRANCCI3_RS06940"
                     /old_locus_tag="Francci3_1382"
     CDS             8766..10028
                     /EC_number="6.1.1.11"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009739606.1"
                     /locus_tag="FRANCCI3_RS06940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1382"
                     /product="serine--tRNA ligase"
                     /protein_id="WP_011435824.1"
                     /transl_table=11
                     /translation="MLDKRFIRENPQAVKDAVAAKGIDLDVDELLQLDRDNRKLQFEVD
                     EAQARRKSFAKQFAGADAARRAELRAEHEAFDRQLKDLREQLARTGGRLSELMLLVPGI
                     PWSGAPVGADESANVVLRTVGEPPEFDFTPLDHTALAEKRGWAEFARARRVAGERAYAL
                     VGDMVMLERAVHSYALDLLRGLDFTPVSVPALVREEPLVGTGMLPKAREEIYAIPADDL
                     YLAGTAEVALVGLHAGEILDVGRLPIRYAGISPCFRREIGSASRDVRGLLRVHQFEKVE
                     QFVLCAADEAESARWHAELLATAERILSDLGLCYEVVECATGDMGVGKFRMNDINTWFP
                     SLGRFRETHSCSTLHDWQARRANLRYRDTDGTVRFAHTLNNTAVATPRLLAALLENFQT
                     ADGEVRVPKVLRPYLGGRELI"
     gene            complement(10001..11002)
                     /locus_tag="FRANCCI3_RS06945"
                     /old_locus_tag="Francci3_1383"
     CDS             complement(10001..11002)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009739605.1"
                     /locus_tag="FRANCCI3_RS06945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1383"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_035958219.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.9e-99, bitscore:
                     328.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.1e-66,
                     bitscore: 222.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQLDAAGIIDPRLRSSYARARALNAAHGRTYYLATLLLPGWKRP
                     HVHALYGFARYADEIVDDLDSTLTEAERARWLHEWGSRFLAALRAGTPAVDVGTEMAGT
                     GRDRHRAEVSVLPAVVDTIHRFKIDPDHFAAFLASMAMDLTVTEYATWDELTVYMHGSA
                     AVIGLQMVPILEPVDDSALPYARDLGMAFQLANFIRDVGEDLRRGRVYLPRTSLDLFGV
                     TREQLAAGVVDGPVRRLLAFEISRARELFRAAEPGIRLLHPTSRDCLRTAFVLYRGILD
                     EVERADYRVLERRVSVGPPRRLAVAGPALVRAVRARRGQGHGMPQISSRPPR"
     gene            complement(11110..12069)
                     /locus_tag="FRANCCI3_RS06950"
                     /old_locus_tag="Francci3_1384"
     CDS             complement(11110..12069)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020462604.1"
                     /locus_tag="FRANCCI3_RS06950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1384"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_011435826.1"
                     /transl_table=11
                     /translation="MSFLAGHWLWLYLGVGALLISYVVVSARRRVYAARLSSTSLLSSV
                     LPRRPQWWRRHVPAALLLLALAGLVFSLARPARAERVPRERATIILAIDVSNSMAATDI
                     APTRLAAAKQGASAFVDQLPPRINLGLVSFAGSATVLVPASADRESVRAGIRGLQLGPA
                     TAVGEGIFASLQAITTAGKRFSDTGQSAPPAAIVLLSDGETTRGRPNNQAIEAARQARI
                     PVDTIAYGTADGTLDVGGQEVPVPVNEQALRDIAEQTGGSYHRATSGDELRSVYRGLGS
                     SIGYRTEYREVTTWFLGLSLGLGFAAAATSLAFTSRLP"
     gene            complement(12066..13118)
                     /locus_tag="FRANCCI3_RS06955"
                     /old_locus_tag="Francci3_1385"
     CDS             complement(12066..13118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435827.1"
                     /locus_tag="FRANCCI3_RS06955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1385"
                     /product="DUF58 domain-containing protein"
                     /protein_id="WP_011435827.1"
                     /transl_table=11
                     /translation="MTDPADRLRAGSVSATDPAVERTLRRLELTVLRRLDGMLLGDHLG
                     LLPGQGSEKAESREYAVGDDVRRMDWAVTARTTVPHVHDLIADRELETWALVDLTASTE
                     FGTGTWQKRDLAIAATAAVGFLTARTGNRMGAIALTQAGPRAIPARPGRDGLRALLHTL
                     ITAPRGAHDRPRRRPDPAAATDLAAAVEGLLRPPRRRGLAVVVSDFLSTDLRWERPLRV
                     LAARHQVLAIEIVDPLELTLPPVGPLPVVDAETGAFVEVPTSSRRLRERYAAAAVAHRS
                     AVSLALRRVGADHLVLRTDSDWLVDIVRFASANRRGRGAGRRPPVGRTDQGGTAAPATS
                     RAGTSRAGSR"
     gene            complement(13115..14224)
                     /locus_tag="FRANCCI3_RS06960"
                     /old_locus_tag="Francci3_1386"
     CDS             complement(13115..14224)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435828.1"
                     /locus_tag="FRANCCI3_RS06960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1386"
                     /product="MoxR family ATPase"
                     /protein_id="WP_011435828.1"
                     /transl_table=11
                     /translation="MDEGHSPAGLAVPDTTSDAALLERALFEIKKVIVGQDRMVERMLV
                     ALLARGHCLLEGVPGVAKTLAVQTLATVVGGSFVRIQFTNDLVPSDIVGARIYRASQEA
                     FDVELGPVFANFVLADEINRAPAKVQSALLEVMSEKQVSLGGVTHRLPEPFLVLATQNP
                     IESEGVYPLPEAQRDRFLMKVNVPYPNPAEELEIVRRMGTSPPLPERVLTPQALTRLQT
                     RADEVFVHHAIIEFAVRLVLATRSPGEAGLPELEGHLAYGASPRASLGLVAAARALGLL
                     RGRDYVVPDDVAAVALDVLPHRLVLSYEALAEGLTADAIAARILGVVPQPQVAPRQQGP
                     HYPTGPHAGGWGTNPRSGFPEYLDQGASG"
     gene            complement(14402..15913)
                     /gene="crtI"
                     /locus_tag="FRANCCI3_RS06965"
                     /old_locus_tag="Francci3_1387"
     CDS             complement(14402..15913)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435829.1"
                     /locus_tag="FRANCCI3_RS06965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1387"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_011435829.1"
                     /sec_met_domain="DAO (E-value: 2.2e-15, bitscore: 55.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGATDHVVIVGAGLAGLSVALRLVGAGRRVTVLERDATPGG
                     RAGLLALGDYRFDTGPTVLTMPELIADALDCVGEDLDRWLSLTRLDPMYRGFFADGSSL
                     DIRADPADTAQEIRALCGPAEAAGFERFVGIVTAMFRTQLRHFIDAQVDSPLSLLRPQL
                     ARLAALGGFRRLDTVVGRHLRDPRTRRMFSFQAMYAGLAPHDALALYAVISYMDCVAGV
                     YHPAGGMHAVAEALAGAAAKHGATLRYETTVTRVEVRGGRAVAVHTAAGERIGADVVVL
                     NPDLPIAYTELLPPSTAPARLRRLRYSPSCFLLLAGARVEYPHTAHHTIHFGRAWRSTF
                     REIIDRGELMSDPSFLVTTPSRTEPAMASAGGHTYYVLFPTPNLTAPLDWSVLRSRYRD
                     EVVATCERHGYRGFGDAIEVEQVTTPADWRARGMAAGAPFAAAHTFRQTGPFRPSNLAP
                     GLANVVFAGSGTRPGVGVPMVLISGRLAAERILGADRGYRSRALC"
     gene            complement(15981..17177)
                     /locus_tag="FRANCCI3_RS06970"
     CDS             complement(15981..17177)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018353507.1"
                     /locus_tag="FRANCCI3_RS06970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_049761056.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-45, bitscore:
                     153.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHTTVPDHTTVDVRRRVSAVLRRFAGSRGALLRGIDDDLIPFV
                     RIATEFLLAEGKRLRPAFCYWGWRGAGGPDCDEIVTAAAAIELLHACALIHDDVMDASD
                     TRRGRPAAHRRFSRVHRTAGWRGDPADFGRSAAILLGDLFLAWADELLAASRMPPEALV
                     RAWPTYGRMRSELMAGQYLDLVGQAEAGPHGGLDPGRAVRIARYKTAGYTVVRPLQLGG
                     LLAGAPPDLLAAYAAFGLPLGEAFQLRDDLLGVFGDPAVTGKPTGEDLRDGRPTGLLAL
                     ALTRAQPAAAARLRTLISPPVRRAGHPEDAGQPENPGYSGGPGCSPGFGPTENPAARAA
                     RVAEARDIIAASGAVAAAEERIAARTATAVEAARRADLDVTTLAALTELAMAATSRSH"
     gene            17277..17969
                     /locus_tag="FRANCCI3_RS06975"
     CDS             17277..17969
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020462600.1"
                     /locus_tag="FRANCCI3_RS06975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_236707299.1"
                     /transl_table=11
                     /translation="MPVFDTAVVVVAVLLVAAALGGLTLLRLPPAELTHTVDGIDAVEV
                     LVAAGRVEISGRDREDVHVALTVRRRPGRSVPVLTRAGSTLRIDGRASDVRVRLTVPPR
                     VRVRAEVLAGEITLWGVGGELSLVTRDGTIAGRELTRGPVAARSRDGDVNLHFSEPPDG
                     VRAQSETGMVTVMLPDGEYGVEVETADPGAADVELTPSAHAACQVVARSVSGRVRVGLA
                     APLGPLSI"
     gene            18214..19110
                     /gene="metF"
                     /locus_tag="FRANCCI3_RS06980"
                     /old_locus_tag="Francci3_1389"
     CDS             18214..19110
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435831.1"
                     /locus_tag="FRANCCI3_RS06980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1389"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_011435831.1"
                     /transl_table=11
                     /translation="MAAVRSLSTQPTTMGEYLATGRASFSFEFFPPKTPDGERQLWTAL
                     RQIEALHPSFVSVTYGAGGSTREGTIRVTERIATDTTLTPIAHLTAVNHSVAELRRVIG
                     NYAGVGVRNVLALRGDPPGDPQGTWTAHPAGLRHADELVRLVRSVGGFCVGVAAFPDKH
                     PRSVDFDSDARYLVGKFDAGADYAITQFFFGADDYFRLVDRVRRLGCDKPIIPGIMPVT
                     NVAQIVRMAQLSGAAFPPALASRLQAVADDPAAVRAIGVEVATELSRRLLDGGAPGLHF
                     ITLNRSSATREIYQAVR"
     gene            complement(19215..19463)
                     /locus_tag="FRANCCI3_RS06985"
                     /old_locus_tag="Francci3_1390"
     CDS             complement(19215..19463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435832.1"
                     /locus_tag="FRANCCI3_RS06985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1390"
                     /product="hypothetical protein"
                     /protein_id="WP_011435832.1"
                     /transl_table=11
                     /translation="MSEQVGGVVETLEDLDPRAVFSAHRDQVILAVRITPIFNTLDLSL
                     VTAVVDAANQAGFALVREHSLRDEWLLCVFDAYDEHD"
     gene            19753..20511
                     /locus_tag="FRANCCI3_RS06990"
                     /old_locus_tag="Francci3_1391"
     CDS             19753..20511
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435833.1"
                     /locus_tag="FRANCCI3_RS06990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1391"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_023840954.1"
                     /transl_table=11
                     /translation="MDDVSTPLPGRDTYLAQWSALHGGYDLARGLWLVRAWLTVVYWLA
                     RPLAARRVRPSAVTAGGAVLTALAIPPAVAGGRWPLLGALVIVLSGLADNLDGAVAILT
                     RRASAWGYVLDSVVDRCGDLAYLLALWCLGAPGGLVIAAGSMLGLLEYTRARAGNAGFD
                     EIGVVTVGERPTRIIIAAVGSFGAGLVPGLANLAASIATTATLAVCAIGLLQLTATVHA
                     ALTAGSGRADETGDDAGGEHDERQPAAGMG"
     gene            complement(20434..21921)
                     /locus_tag="FRANCCI3_RS06995"
                     /old_locus_tag="Francci3_1392"
     CDS             complement(20434..21921)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435834.1"
                     /locus_tag="FRANCCI3_RS06995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1392"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_011435834.1"
                     /transl_table=11
                     /translation="MARVVVIGAGVGGLAAAARLAATGHDVTVCEQSSRTGGKLGWYER
                     DGFGFDTGPSLLTMPGVFEDLFTATGGPLRGEVELRRLDPIASYRFADGTTLAAHADDD
                     AFVAELDDRIAPGSGEDWRRLADRACRVFDAAEGPFLSSPVSATGLVRLAWSAPGDIAA
                     IAPGRSLRRLGLRYLRDPRLRMILDRYATYSGSDPRHAPAALVSVVHAERRFGGWYVAG
                     GLRRLGDALTRRAEERGVRILLDAPVLAVTRTPGGRVDGVRLADGIRLPADVVVANADA
                     AALYGRLVNDRVGRRRLRRTVPSMSGFVLLLALTGRTPGLGHHTVTFPADYDAEFDAVF
                     AGRLAADPTIYLAAPADPACAPPGCEAWFILVNAPPHRGAGGHNGAGTLDWDRPGLTDG
                     YARRILDVLAARGFDVRSRLRWYETITPADLERRTGTVGGSIYGGSSNGVRAAFLRPPN
                     ASRVPGLFLVGGSTHPGGGLPLVVLSAGIVAGLIGPA"
     gene            complement(22070..23257)
                     /locus_tag="FRANCCI3_RS07000"
                     /old_locus_tag="Francci3_1393"
     CDS             complement(22070..23257)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435835.1"
                     /locus_tag="FRANCCI3_RS07000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1393"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_011435835.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.1e-19,
                     bitscore: 67.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPWRTGHGTRHRTVPRSPARWLAGRCWSGAVRSAAVASTAIAV
                     HTAVNARLLRVPPPARPVRERVTVVLPVRDEARSLPRCLSALLGSRWVPDLEILVYDDG
                     STDGTGEILARWAARDNRIVALRGAEPPAGWLGKPHACARAAAAATGTVLVFVDADVTV
                     APDGVARTVLLLRDAGLDLVSPYPRQEAAGVAERLIQPLLQWSWLALLPLRLAERSARP
                     SLSAAGGQLLAVDVAAYRRAGGHEGVRDQVIEDVALLRRLKRAGGRGVVVDGTDLAVNR
                     MYSGWSQLRDGYAKSLAVAGGSTLGSVGQIGMLAWLFVVPAVAALGGSGPGAVGYLAGV
                     AGRVLAARRTGGRSWPDAAAHPASVSLLGYLTAVSWWRRRRGTARWKGRPVTRCP"
     gene            complement(23254..24081)
                     /gene="cruF"
                     /locus_tag="FRANCCI3_RS07005"
                     /old_locus_tag="Francci3_1394"
     CDS             complement(23254..24081)
                     /EC_number="4.2.1.161"
                     /codon_start=1
                     /gene="cruF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435836.1"
                     /locus_tag="FRANCCI3_RS07005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1394"
                     /product="bisanhydrobacterioruberin hydratase CruF"
                     /protein_id="WP_011435836.1"
                     /transl_table=11
                     /translation="MTADALFTGSARPARPTAVPWIFAAATVAVQLPCPLVTGSAGAAL
                     AIASIVLFFASSVSHALLTRGRAWTAGFLAVTVGGGLLVETVGVHTGWPFGRYVYGSAL
                     GTRLYGVPVVVPMAWAMATYPAYVLARRHHRGRARTVVLAALVLAAWDLFIDPQMVAAG
                     YWRWLGGGPTLNGIPLTNTAGWVAVAIAMTAALTALPDQAGSTARDERAPLALLLWAYV
                     SSTLANLTFFDRPGVAAAGGIAMGAALVAAARAGPRDRARAGDRPVPAGSPPR"
     gene            complement(24078..24656)
                     /locus_tag="FRANCCI3_RS07010"
                     /old_locus_tag="Francci3_1395"
     CDS             complement(24078..24656)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011603336.1"
                     /locus_tag="FRANCCI3_RS07010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1395"
                     /product="N-acetyltransferase"
                     /protein_id="WP_232234953.1"
                     /transl_table=11
                     /translation="MRTRLDDVIAVYKAAFLDHHEPDPQRAARDRAAHARRHFERRDLR
                     AVAAVTPDDELIGITYALPGRVGQWWHDVVAGALPPDSAAYWLDDCLEIVELHVLPAYQ
                     GRAIGRTILRELLRGAPQRTAALSALEPPGSPARRLYDHEGFVPLLSDFQFPGTLTPYA
                     VLGKELRGRSPARPDAASAQGADRHAPVR"
     misc_feature    24948..24962
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(26560..26574)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    complement(26917..26930)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    complement(27131..27145)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(27143..27158)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.58"
                     /tool="antismash"
ORIGIN
        1 gcgcactgga agtacaagga ggacggggtt gcggcccggc cctcggcggg gaccccggag
       61 ggcgggcggg ccggtcggcg caagggcgga cccgatgcgg acctcatgac ctggctgcgt
      121 caggtgctcg actggcagcg ggagaccgcg gacccgggag agttcctcga cagcctgcgg
      181 ttcgccgccg agaccgacga ggttttcgtc ttcaccccca agggcgacgt catcccgctg
      241 cctgccgggt cgacctcggt ggacttcgct tacgcggtgc acaccgacat cggccaccag
      301 tgcgtcgggg cccggatcaa cggccgtctc gcggccctgg acaccccgct ggacaacggc
      361 gacgcggtcg agatcttcac ctcgcgggcc cattcggccg gcccgagcga ggactggttg
      421 atgttcgtcc gttcgtcgcg ggccaggacg aagatccgcc agtggcacgc ccgtgggcgc
      481 cgggaggacg cgatcgtcgc cggccgcgac gcgatcggcc gcgcgatgcg ccgccacggc
      541 ctgccgctgt cccgcctgat gagcggggac gcgctgttga acctggccaa ggacctgcgc
      601 tacgccgacg tggccgccct ctacgcggcc gtgggggaga accacgtcag cgcccagtcg
      661 gtggtctcgc ggctgctcgt ggccctcggc ggtccggagg gggccgagga ggacgcgggt
      721 gagaccgagc tgccgatccg cacgctgcgt cgctcgaccg gggaggcggg ggtgctcgtc
      781 accggtgctc ccgacgtgtg gacgaagctc gcccgctgct gcacccccat gcccggcgac
      841 gagatcgccg gtttcgtcac ccggggcaag ggcgtgtcgg tccaccggac ggactgctcc
      901 aacctgtcgg ggctgcgcgg cgggccgcac gaccgcacgg tccaggtcga gtgggcgccg
      961 tcgtcgggct cggtgttcct cgtcgtgatc caggtcgagg cgatggaccg taccaaacta
     1021 ctttcggatg tcacccgggt actgtccgac cggcacgtga acatcctgtc ggcgtcggtg
     1081 gccaccacac gggatcaggt ggcggtcagc cgcttcacgt tcgagatggg agacgccaag
     1141 catctccggc acatcctgag tgcggtgcgt gccatcgagg gcgtatacgg ctgtttccgc
     1201 gttacctcgg gcgtacaggt ctaacgggtc gaatcagggg ggtgccgtgg atgctgagac
     1261 cgtgggtgcg ggtctgccgg ccggcggcgg tctgaccccc gcgctgtccc gggccgacgg
     1321 cggtgccgac gaggcctccc gggccctgtc ggcggcccgg caggcgagcg tgcgtctcgc
     1381 ccacctggcc cggcggatgg cgacaccgcg gatgtcccag gtgccgccgg agctgcgtga
     1441 catcgtcgag gcgcatcgcg actatcatcc gcgcgccgac atcggcctgc tggtgcacgc
     1501 ctacggcgtc gccgagcggc tgcacgccgg tcagatgcgg cgcagcgggg atccgtacat
     1561 cagccatccc ctcgccgtca ccgaggtcct cgcggagctg ggggtggaca cgactaccct
     1621 gatcgctgcc ctgctgcatg acacggtcga ggacaccggg tacaccctcg actccgtcac
     1681 ccaggagttc ggcgcggagg tggccaacct cgtcgacggt gtcaccaagc tggacaagat
     1741 gcggttcggg gaggccgcgg aggccgagac gctgcgcaag ctgatcgtgg ccttggcccg
     1801 ggactaccga gtactggtca tcaagatcgc ggaccggttg cacaacatgc gcacgctcgc
     1861 cttcatgtcc cctcccaaac aggtgaagat ctcccgggtc acgctcgagg tcctggcccc
     1921 gctggcccac cggctcggcg tcagtgtgat caagcgagag ctggaggacc gggcgttcgc
     1981 cgtgctccat cccgccgagc acgcccggat tgccgccacg gtggacgagt tcaccgccgc
     2041 tgagcgcgcg gccggaaccg tcgcggcgct ggtggcacgg ttgcgagccg ggctcgcggg
     2101 ggctcgcatc gacggcgccg tctccatccg ggtcagccac ctgttctcga tctacaagcg
     2161 ggctcaggag cgcaaccggc ccgtccagga ctacaccgac ctcgtccgcg tcctcgtgct
     2221 cgttgacgag gtgacggact gttacgcggc gctgggtgtc atccacgccc tgtggcgacc
     2281 ggtgcccggc aggctgcgcg acttcgtggc taccccgaag ttcaacatgt accagtccct
     2341 gcacacgacg gtgaccgacg gcgccggccg ctccctcgac atccagatca ggacgccgtc
     2401 gatgcaccgg ctggccgaga ccgggatcgt cgcccgaccg gtcggccccg gcgcggacgg
     2461 cgcccgcctg gagggcctgt cctggttgca cagcttgctg gactggcagg aggaggtcga
     2521 ctcggacgag ttcctcgagt cgctgtcctc agacctggat gccgacgagg tgctggcgtt
     2581 cacgcccaag ggcaggatgc tcgcactgcc ggcccggtcc tccccggtgg acgtcgccta
     2641 cgccgtgcac accgacatcg ggcaccgggc gatcggcgcc cgggtcaacg gtcggctcgt
     2701 cccgttgcat acccggctgc gcaacggcga cgtcgtcgag atcctgacct ccaacctccc
     2761 cggcgcggga ccgtcggagg actggttgca cttcgtcagg acctcccggg cccgggtacg
     2821 tatccggcgc cggctggccc ggcagcgcag ggacaccgcc gccggggcgg ccgagccggg
     2881 cgtcacgacc acccggtccg ggagcggcgg cggggcgcgg accgccggcg gcgcggacgg
     2941 cgcctcgtcg ggcctgccgt cgccgacccg tccgatcgcc cggcgtggga tgcccagcct
     3001 cgcggccgtg gcagacgacg gggtgggtgg tcgggtgccg gcgaggctgg cgcgatgttg
     3061 ccttccgctg cccggagacg tggtcgtcgg cttcgcgacg cacggcagca ccgtgtctct
     3121 gcaccgccgg gagtgcatga acgccaccga ggcggggtcg gaccgcgagc gcgtcgcggt
     3181 ggcgacctgg tcggcaccac aggcgcagat ttttcccgcg gagatcgccg tcgaggcgtt
     3241 cgaccgctac gggctgctcg cggacatcac cgaggtgctc tcggagatct cggcgtccgt
     3301 ccgcgcggcc tcgacgacca catccgatga tcgggtcgcg catgcgcgtt tcacgatcga
     3361 ggtcaccggg ccggagcaac tggacaaggt gctcggcgcc gtgcgcggcg tcggcggtgt
     3421 ctacgactgc taccgcgtgt gccagaccca ggggtcgtcg gctcacggcg cgcccgccgg
     3481 ggacgggtga agccagcgca gggcggcggt ggcaccgacc cgggcggggg accgcggcag
     3541 cggtaggacc aaccggtggg tgagaccagg ctggttacgg gagcaggccg gtcttctccg
     3601 gccggcgtgg ggtgctgtct cttgcgccca gcgtggcctt tccgcgccgg aatgtaccct
     3661 cccgatcaac cggcggtaaa cggcttgcga ctgaaccgcc cattccgggt ggatccgggt
     3721 ggaatgtcac gcggagaata cggaccatcc taccggacgc cgtaaattca acggctaccg
     3781 ccactgatcg atgtagggta tcttgcgtat ccatcgtttt agagatggga gtgcgcgtgg
     3841 gtcaccttca ggtcatcgtg agtatcgact cccgggaaag cgctgaccgt atcggtagga
     3901 tcctggtgga ggcgcgtctg gtcgcctgtt tccaggtgat cggaccgatg agcagcacct
     3961 accgctggaa gggccagatc gagcaggccg aggaatggct ctgtctggcg aaaacgacca
     4021 ccgaacgatt cgatgagcta catgagcggc tcgtggtcct ccacccctac gaaaatcccg
     4081 agatcattgc cacgccgatc gtcgccggcc atgccgacta tctgggctgg atcagcgccg
     4141 agacggcacc caccgtcagg tgagtgcccg cagctgctcg tcgaactcgc gcacggcctg
     4201 ggtgtgctgc cagggccgca ggtgctcccg ggcgcggcgg atacgggcca ggcccagcga
     4261 gaagtccgtc tggagcacga tcgcgaggga ctcggccgcg aagtggcagg ccgcctcgat
     4321 ctcccgccgc tggatgtgca cctccgcgat gtcgctcatc agcaacgacc gcttcttcgt
     4381 cgcaccggga gcggccgccc gcagtgcctc ggtggcggcg gcgtaggccg cggcgggtcg
     4441 ccgtagccgc gtgtaggtgg tgaccttcag gccatcgagc cggccccggt cgaagaactg
     4501 cgtccagacc cggtccccgt cgctctcacc ccggtcgaag gcatcctggg cacggtcgag
     4561 ggcggccagc gccgcccggc cctcgccgcg agcggcctgc tcctcggcct cccgggcagc
     4621 cagccaggcc ctggtcatca ccgtgctgcc cgtggcggct cgccgctggg cttcaccgag
     4681 cagcgcgcag gcctggtcgt ggcggccacg gctggcggtc tggtagctct cgtaaccgag
     4741 tacgcaggcc cacagggcgt ggtcatcggc ctcgcgggcg gcctcgatgg ccacccggta
     4801 gtaggcgacg gccgcgggca ggtcgttcat gtcgaacgag agccatccgg cgagcgccgc
     4861 cgtctccccg gcggtggagg tcagctcacg gcgcaccggg gaccggctcg tggtctccag
     4921 cagctgactg agcctgctca gatgcccggt gacccgctgt atcaggatcc gggcgggaac
     4981 gcgttcctct aagccgtaca gccccgcggt gagctggccc agctcgttga cgagctccgg
     5041 ggtcaccgtg ctacggcgac gcagcgccgc cgagaggcgc tcccagggcg gggtgtccgt
     5101 gacgccgttc atgggcacga cggcgacgcc gcccgccgcg gcgaagagcc ggagaaagtc
     5161 ccgacgttcc acgggaatac cgttcgtgtc gatcatgtcg gtgccggggt gaagtacgag
     5221 tgtgcccgcg gcgcccgtct cgcaggccgc ctgttcaagg ttcatcgacg cggcgacggc
     5281 cgtaccctga ccggttccgc cccgcagtgc tccgacggcg gcgggaagcg cttcgtcatc
     5341 cacgaaaccg agctccgccg acgaccggcc gaatagcgcc cgcaacaacc gctgataacg
     5401 caggcttggt ttcttgtcgc ccttctccca cttgcagatc atgttgccgg tcaccccggc
     5461 ctcgcgaccc tcgtggatga cggagaaccg acggatctcg gtggcgagcc gttcctgcga
     5521 ccagccccgt tcctcccgac tcagtcgcag ccgggtgttg ggtgtgcggg tgttgggtgt
     5581 gcgggtggtg ggcgtcctgt caccaccgga tacctcaggt gttggcgcgg aggccaccgg
     5641 tgcgcgggga actgccgaag gaccggtcgt gagctgcatc ggggcctccg aagtcaatcg
     5701 gttgactcca ggagcttaac cctctgtgag ataagacggt catgctcggg cgtggtccct
     5761 tcgggaccat ccacggcaaa agtgtggtca tcccgacgcg cctgcggccg ccagcgtctt
     5821 cgccgagtgc cgccttctag agtgtgatgg cgtgagagcc ggccccctcg accgaagccc
     5881 tcgtccacga cgtcccgttc caccagcccg accgctgcgc gcgtggcagc gtgcggccct
     5941 ggagatctac cggtcacggt cgtcgtcggg cgcccgggac ttcatggcgg tcgccacccc
     6001 gggcgccggg aagacgacct tcgccctgca ggtggccgcc gaccttctca ctgccggcga
     6061 gatcagtcgg atcaccgtcg tcgcgcccac cgagcacctc aaacgccagt gggccgtggc
     6121 cgcggcggag gttggtgtcg acctcgatcc ggacttccgc aactcggccg gggcgacatc
     6181 ctccgactac accggtgtcg ccgtgaccta cgcccaggtg gcggcgcatc cggccctgca
     6241 ccgtgcccgg accgccgcgc gtcgcaccct gatcgtcctg gacgagatcc accacgccgg
     6301 cgacgcgctg tcatggggtg aggcgatccg ggaggcgttc accccggccg cgcgtcgcct
     6361 cgccctgact ggtactccgt ttcgctccga cgtcaacccg atccctttcg tcacctacct
     6421 gccgggcccc gacggggtga tgcgcagcat cgcggactcc tcctacggct atgccgaggc
     6481 gctgcgcgac ggggttgtcc gcccggtgct cttcctcgcc tactcgggcg agatgacctg
     6541 gcggaccagt gccggcgcgg aactgagcgc ccgactcggg gagccgctca ccaacgagca
     6601 gaccgccgcc gcgtggcgca ccgcgctcga cccgggcggg gactggatgc cggcggtgct
     6661 cgcctccgcc gacacccggc tgtcccaggt gcgggccggc ggcatgcccg acgcgggcgg
     6721 gctggtcatc gccacggatc acgcggccgc gcgcgcctac gccgcgctgc tcacccggat
     6781 caccggcacc tcgcccgtgc tgatcctctc cgacgacccg accgcgtcga ccaagatcga
     6841 tgactttcgc cggtcggccg accggtggat ggtggcggta cggatggtca gtgagggcgt
     6901 ggacgtgcct cgcctggcgg tcggggtcta tgcgacctcg gcgtcaaccc cgctgttctt
     6961 cgcccaggcc gtcgggcggt tcgttcgggg ccgcggtcgc ggggagacgg cgtcggtctt
     7021 cctcccgagc gtgccgtccc tgctggcgct ggctggcgag atggaggtcc agcgggacca
     7081 cgccctggag aagtccccgc gcgatccgga cgccttcgac gacgacgcgc tgcgggacgc
     7141 caaccggcgc aaggacatcc ccgacaagcc ggacaccttg ttcacggcgt tgggatcctc
     7201 ggcccatctc gaccgagtga tcttcgatgg cggcgagttc ggcaccccgg cggcccccgg
     7261 gtccatcgag gaggaggact tcctgggcct gccgggcctg ctggagcccg atcaggtcgc
     7321 ggttctgctg cgccagcggg aggccgccca gcaggccgcc cagcaggccg ccacgcgccg
     7381 tgccgctgcc cgtgccgcgg attcgccggt cgtcccgccg gcccgcgagg gcgtgcagcc
     7441 ggcggtcgag gcggccaccc ggcccgtgca cgaggtgatc ggcgagctgc gcaaggagct
     7501 gaaccggctt gtcggcgcac acttccaccg cacgggcaaa ccgcacggga tgatccacgc
     7561 cgagctgcgc cggacctgtg gcggtccgcc gagcggccag gccaccgccg cgcagctcca
     7621 ggcccgcatc gacaccatcc gccgctgggc cggttgaccg gcgggtcagc cgccctgggt
     7681 gatcgtgatc gaaagaatct tcggcttgct cgccggggca ccatcggagc cgccgccctc
     7741 gacgccgggc ccggtgagct tgtcgagcac gtcgagtccc ttggtgatct tcccgaagac
     7801 ggtgtaattg ccggcgagcg ccgccgcgcc ctgcggggtc gggttctggt agttgatgaa
     7861 gaactgactg ccgttgctgt ccggcagttg gctgtgcgcc atcgccagca cgcctcggtc
     7921 gtaggtcacg ccctgggtat tctcgttggc gtacccgtac cccgggccgc cgttgccggt
     7981 tccggtggga tcgccgcact gcaggaccga gatgcctgcg tcggcccccc cggtctggcg
     8041 gtggcacgtg gtgccgtcga agtacctggc gtcggcgagc gtgcgcaggg cgtgcaccgt
     8101 gcatggtgcc ttctgggcgt ccaaggcggc cgtgatggtg ccggcgtcgg tgatgatcac
     8161 cattgtcgcc ggggacgtgt cgacggtggc cgcggccgcc ggcagggtgg cgccgcgggc
     8221 cggggcctcc ccgttggagg tgtaggtgca ctgcccgacc ctgctggtct gacggggggc
     8281 ggccgatggt gtcggtgcgg tcgcggtggg tgcggtcgcg gtgggtgtcg tcgcggcacc
     8341 ggcggcggcc acgtcgggct ggtcgtcctt gccggtgagc aggatcgcgg cgatcgtcga
     8401 tgccgcgacg acgatcgcga tgaatccggc gacgatcgcg agccgctgct gacgacggcg
     8461 atgggcgagc cggcgccgct gcgcctgccg ggccgcccgg gcctcggcga gctcgcgttg
     8521 acgtcgctcc tttgaactgg ccaccgtcgc cggcctccct cgcttctgat gcggtctgct
     8581 ggttctggtg tggtctggtt ctggtgtggt ctgtgcaccg taaccggtga gcggcggatc
     8641 gccccgcatg gtgcctgccg gggcgggtgc ccgccgggcc gggagcggac cggtgcgcgg
     8701 gccggacggc tggtagcgtt accgcaaagc acaatgcggt accgatcaga ggctgacgcg
     8761 attccatgct cgataagcgc tttatccggg agaatccgca ggccgtgaaa gacgcggtcg
     8821 cggccaaagg cattgatctg gatgtcgatg aactgctgca gctcgaccgg gacaatcgca
     8881 aactgcagtt cgaggtggac gaggcgcagg ctcggcgcaa gagcttcgcg aagcagttcg
     8941 ccggggccga cgcggcccgg cgggccgagc tgcgggccga gcacgaggcg ttcgaccgcc
     9001 agctgaagga cctgcgcgag cagctggccc gaaccggggg ccggctgtcc gagctgatgc
     9061 tgctggtgcc gggcatcccg tggtcgggtg cgccggtggg agccgacgag tcggccaacg
     9121 tggtgttgcg gaccgtcggc gagccgccgg agttcgactt caccccgctc gaccacacgg
     9181 cactggccga gaaacgaggg tgggcggagt tcgcccgggc ccggcgggtc gcgggggagc
     9241 gggcgtacgc cctcgtcggt gacatggtca tgctggagcg cgcggtgcat tcctatgcgc
     9301 tcgacctgct gcgcgggctg gacttcaccc ccgtgtcggt gcccgccctg gtccgggagg
     9361 agccgctcgt cggcaccggg atgctaccca aggcccgcga ggagatctat gcgatccccg
     9421 ccgacgacct ttacctggcg gggactgccg aggtggctct tgtcggcctg catgccgggg
     9481 agattctcga tgtgggccgc ctgccgatcc gctacgccgg catctcgccg tgctttcgcc
     9541 gggagatcgg cagcgccagc cgggacgtcc gcggtctgct gcgcgtccac cagttcgaga
     9601 aggtcgaaca gttcgtgctg tgcgccgctg acgaggccga gtcggcccgc tggcatgccg
     9661 agttgctggc cactgccgag cggatcctgt ccgacctcgg gctgtgttac gaggtcgtcg
     9721 aatgcgccac cggggacatg ggcgtcggca agttccggat gaacgacatc aacacctggt
     9781 tcccctcgct cggtcgattc cgcgagacgc acagctgctc gacgctgcac gactggcagg
     9841 cgcgccgggc gaacctgcgc taccgcgaca ccgacggcac cgtgcgtttc gcgcacacgc
     9901 tcaacaacac cgccgtggcg accccacggc tgctggcggc gttgctggag aacttccaga
     9961 ccgccgacgg cgaggtacgc gttcccaaag tgctgcggcc ctacctgggg ggccgtgagc
    10021 tgatctgagg catcccgtgg ccctggccgc gacgcgcccg gacggcccgg accagggcgg
    10081 gtccggcgac cgccagccgg cgcgggggcc cgactgacac gcggcgttcg agcacccggt
    10141 agtcggcgcg ctcgacctcg tcgaggatgc cccggtagag gacgaacgcc gtccgcaggc
    10201 agtcgcgtga ggttgggtgc agcaggcgga tgccgggctc ggcggcgcgg aacagctccc
    10261 gcgcccggct gatctcgaag gccagcagcc ggcggaccgg cccgtcaacg acgccggcgg
    10321 ccagctgctc ccgggtgacc ccgaacaggt ccagcgaagt ccggggcaga tagacgcggc
    10381 cgcgccgcag atcctcgccg acgtcgcgga tgaagttggc gagctggaag gccatcccca
    10441 ggtcgcgggc atagggcagg gcgctgtcgt ccactggctc gaggatcggc accatctgca
    10501 ggccgatcac cgcggccgat ccgtgcatgt agacggtcag ctcgtcccag gtcgcgtact
    10561 ccgtcacggt gaggtccatc gccatcgagg ccaggaacgc cgcgaagtgg tccggatcga
    10621 tcttgaagcg gtgaatggtg tcgaccaccg cgggcagcac cgagacctcc gcgcggtgcc
    10681 ggtccctccc ggtgccggcc atctcggtgc cgacgtcaac ggcgggtgtc cccgcccgta
    10741 gcgccgcaag gaaccggctg ccccactcgt gcagccagcg cgcccgctcg gcctcggtca
    10801 gcgtggagtc gagatcgtcg acgatctcgt ccgcgtagcg ggcgaagccg tacagcgcgt
    10861 ggacgtgggg ccgcttccac cctggcagca gcagggtggc caggtagtac gtgcggccgt
    10921 gggcggcatt gagcgcccgg gcccgcgcat aggaggaacg tagtcgagga tcgatgattc
    10981 cggccgcgtc gagctgcccc acgttagtca gcgtagccac ccagcgaggc ggatagcgac
    11041 ggctcccgcc cgatcggggt cgacctgccc cggggcgtcc ggttgacccc ctcgtcggcg
    11101 tcgatcccct cagggaagcc gggacgtgaa cgccagggac gtcgccgccg cggcgaatcc
    11161 cagccccagg gacagcccga ggaaccaggt ggtgacctcc cggtattcgg tccggtagcc
    11221 gatcgagcta ccgagccccc ggtagaccga acgcagttcg tcgccggagg tggcacgatg
    11281 gtacgagccg ccggtctgct ccgcgatgtc acggagcgcc tgttcgttga ccggcaccgg
    11341 cacctcctgg ccgccgacgt cgagcgttcc gtcggcggtg ccgtaggcga tggtgtccac
    11401 cgggatacgg gcttgccgcg ccgcctcgat cgcctggttg ttcggccgcc cacgggtggt
    11461 ctccccgtcg gagagcagca cgatggcggc cggaggcgcg ctctgccccg tgtcggagaa
    11521 ccgtttgccg gcggtggtga tcgcctggag cgaggcgaag attccttcgc cgacggcggt
    11581 cgcgggaccg agctgcaggc cgcggatgcc ggcgcggacc gactcgcggt cggcggacgc
    11641 gggcaccagg accgtcgcgc tgccggcgaa cgagaccagc ccgaggttga tacggggagg
    11701 gagctggtcg acgaatgccg aggcgccctg cttggcggcc gccagccggg tcggggcgat
    11761 gtccgtggcc gccatcgagt tggagacgtc gatcgccagg atgatcgtcg cgcgttcccg
    11821 gggaacccgc tcggcccgcg ccggtcgcgc cagggagaac accaacccgg cgagggcgag
    11881 cagcagcagc gccgccggga cgtgacggcg ccaccactgc ggtcggcggg gaagcaccga
    11941 ggacagcagc gacgtcgacg acagccgggc ggcatacacc cgccgccgcg ccgagaccac
    12001 gacataggag atcagcaacg cgccgacccc caggtacagc cacagccagt gcccggccag
    12061 gaagctcacc ggctgcctgc ccgactggtg cctgcccgac tggtggcggg cgccgccgtg
    12121 ccaccctggt cggtccgacc cacgggcggg cggcggccgg ctccccggcc gcgccggttc
    12181 gccgaggcga accggacgat gtcgaccagc cagtccgagt cggtgcgcag gaccagatgg
    12241 tcggcgccga cccggcgcaa cgccagcgag accgcgctgc ggtgggcgac ggcggccgcg
    12301 gcgtaacgtt cccgcaaccg ccgcgacgac gtcgggacct cgacgaacgc ccccgtctcg
    12361 gcgtcgacga cgggcagcgg cccgaccggt ggcagggtca gctcgagcgg gtcaacgatc
    12421 tcgatggcga gcacctgatg ccgcgccgcg agcacccgca gcggccgttc ccagcgcagg
    12481 tcggtggaca ggaagtcgga gacgacgacc gcgagccccc ggcggcgcgg cgggcgcagc
    12541 aggccctcca ccgccgcggc gaggtcggtg gccgccgccg gatcgggccg gcggcggggc
    12601 cggtcgtgcg cgccgcgagg cgcggtgatg agcgtgtgca gcagcgcccg cagcccgtcc
    12661 cggccgggcc gggccgggat cgcccgtgga ccggcctggg tcagcgcgat cgcgcccatc
    12721 cggttgccgg tgcgggcggt caggaagccg accgcggccg tggcggcaat cgccagatca
    12781 cgcttctgcc aggtaccggt gccgaactcg gtgctggcgg tgaggtccac cagcgcccag
    12841 gtctcgagct cccggtcggc gatgagatcg tggacgtggg ggacggtggt ccgggccgtg
    12901 acggcccagt ccatccggcg cacgtcgtca ccgacggcgt actcgcggct ctcggccttc
    12961 tcgctgccct gaccgggcag cagcccgaga tgatcgccga ggagcatgcc gtcgagacgg
    13021 cggagcacgg tcagttcgag ccggcgcagg gtccgctcca ccgccggatc ggtcgccgac
    13081 acggagccgg cccggagccg gtccgcgggg tccgtcatcc ggacgcaccc tggtcgaggt
    13141 attccgggaa gcccgaacgc gggttcgtcc cccacccgcc ggcatgcgga ccggtggggt
    13201 agtgggggcc ctgctggcgg ggcgccacct gaggctgcgg gaccacgccc aggatccggg
    13261 cggcgatcgc gtccgcggtc agcccctcgg ccagcgcctc gtacgagagc accaggcggt
    13321 ggggcaggac gtccagggcg accgcggcga cgtcgtcggg tacgacgtag tcgcgcccgc
    13381 gcagcaggcc gagcgcgcgg gccgccgcga ccagtccgag cgaggcgcgc ggcgaggctc
    13441 cgtaggccag gtggccctcg agttcgggta gacccgcctc gccgggggac cgggtggcga
    13501 gcaccagccg gacggcgaac tcgatgatgg cgtgatggac gaacacctcg tcggctcggg
    13561 tctgcagccg ggtcagcgcc tgcggggtca ggacccgctc ggggagcggt ggcgaggtgc
    13621 ccatccgccg gacgatctcg agctcctccg ccgggttcgg gtaggggacg ttgaccttca
    13681 tcaggaaccg gtcccgctgc gcctccggta gcgggtagac accctcggat tcgatcgggt
    13741 tctgggtggc cagtaccagg aacggctcgg gaagccggtg ggtgaccccg ccgagcgaga
    13801 cctgcttctc cgacatcacc tccagcagcg ccgactgcac cttcgcgggt gcccggttga
    13861 tctcgtcggc gagcacgaag ttcgcgaaga ccgggccgag ctcgacgtcg aacgcctcct
    13921 gactcgcccg gtagatgcgg gcaccgacga tgtcggaggg cacgaggtcg ttggtgaact
    13981 ggatgcggac aaacgaaccg ccgacgacgg ttgcgagggt ctgcacggcc agcgtcttcg
    14041 cgaccccggg cacgccctcc agcaggcagt ggccccgggc gagcagggcg acgagcatac
    14101 gttcgaccat ccggtcctgt ccgacgatca cttttttgat ctcgaacagg gcgcgttcga
    14161 gcagcgccgc gtccgacgtg gtgtccggta cggcgaggcc ggccgggctg tgcccttcgt
    14221 ccatggcagc attgtcccag ccgcatcgtg gaacagggtg ccaaaggact cggcacggcc
    14281 tggccggaag cctcttctaa gccgctcttc agcaacttct cggcggtggg aaatgttcgg
    14341 ggcaccgggg caccggggca ccgggctgtc gggctgtcgg gctgccgggg tgcgtcacgg
    14401 gtcagcacag ggcgcgggaa cggtaacccc ggtcagcgcc gaggatccgc tccgcggcca
    14461 gccggccgga aatgaggacc atcgggaccc cgacgccggg ccgggtgccg ctgccggcga
    14521 acacgacgtt cgcgaggccc ggggccaggt tcgaggggcg gaacggaccg gtctggcgaa
    14581 aggtgtgggc cgccgcgaac ggggcgcccg ccgccatccc gcgggcccgc cagtcggcgg
    14641 gcgtggtgac ctgctccacc tcgatggcgt cgccgaagcc tcggtagccg tggcgttcgc
    14701 aggtggcgac cacctcgtcg cggtagcgcg agcgcagcac cgaccagtcg agcggggcgg
    14761 tgaggttggg tgtggggaag agcacgtagt acgtgtggcc gccggccgag gccatcgcgg
    14821 gttcggtgcg tgagggggtg gtgacgagga aggacgggtc gctcatcagc tcgccgcgat
    14881 cgatgatctc gcggaaggtc gaccgccagg cccggccgaa gtggatggtg tgatgcgcgg
    14941 tgtgcgggta ctccacgcgc gccccagcca gcaggaggaa gcacgagggc gagtaccgca
    15001 ggcggcgcag gcgggccggc gccgtcgagg gaggcagcag ttcggtgtag gcgatcggca
    15061 ggtcggggtt gagcaccacc acgtcggcgc cgatgcgctc ccccgccgcg gtgtgcaccg
    15121 cgaccgcccg gccgccccgc acctccaccc gcgtcaccgt ggtctcgtag cgcagggtgg
    15181 caccgtgttt ggccgcggcg ccggccagcg cctcggcgac ggcgtgcatg ccgccggccg
    15241 ggtggtagac cccggcgacg cagtccatgt aggagatgac ggcatagagg gccagtgcgt
    15301 cgtgcggggc gagcccggcg tacatcgcct ggaaggagaa catccgccgg gtccgcgggt
    15361 cccgtagatg gcggccgacg acggtgtcga gccggcggaa gccgccgagg gcggccagcc
    15421 gggcgagctg cgggcgcagc aacgacagcg gggagtcgac ctgcgcgtcg atgaagtggc
    15481 gcagctgggt gcggaacatt gcagtgacga ttccgacgaa ccgctcgaag ccggccgcct
    15541 ccgccgggcc gcacagcgcc cggatctcct gtgcggtgtc ggcggggtcg gcgcggatgt
    15601 ccagcgacga accgtcggcg aagaaccccc ggtacatcgg gtcgagccgg gtcagtgaca
    15661 gccagcggtc gagatcctcc ccgacacagt ccagggcgtc ggcaatcagc tcgggcatgg
    15721 tcaggacggt cggtccggtg tcgaaacgat agtcgcccag tgcgagcagg ccggcccgac
    15781 cgccgggggt cgcatcccgc tcgagcaccg tcacccgccg gccggctccg accaggcgca
    15841 gcgcgaccga cagaccggcg agaccggccc cgacgatgac gacgtgatcc gtcgctccgg
    15901 tcaccgtgcg cacctgccac ctgcttcctg gtcgatggac ttccctgtcg atggtgcggt
    15961 tacccgatgt ggtcggttgc tcaatgtgat cgcgaagtcg ctgccatggc gagttccgtc
    16021 agggcggcga gggttgtgac gtccagatcc gcccgtcggg ccgcctcgac cgccgtggcg
    16081 gtccgggcgg cgatccgttc ctcggcggcg gccaccgctc cgcttgcggc gatgatgtcg
    16141 cgggcctcgg cgacccgggc ggcgcgggcc gcggggttct cggtgggccc gaatcccggg
    16201 gaacatccgg gtcccccgga atacccggga ttctcgggct gtcccgcatc ctcagggtgc
    16261 ccggcgcgcc ggaccggcgg ggagatcagc gtgcgcagcc gggccgccgc ggccggctgc
    16321 gcacgggtca gcgcgagcgc cagcaggcca gtgggccgcc cgtcacgcag atcctccccg
    16381 gtgggttttc ccgtcaccgc cggatcgccg aacacgccca ggaggtcatc gcggagttgg
    16441 aacgcctcgc cgagcggcag gccgaacgcc gcataggccg ccaacaggtc cggcggcgcg
    16501 cccgcgagca gaccgccgag ctgcagggga cggaccaccg tgtaaccggc ggtcttgtac
    16561 cgggcgatgc ggaccgcccg cccgggatcg aggccgccgt gcggaccggc ctcggcctgg
    16621 ccgacgaggt cgaggtactg ccccgccatc agctcgctgc gcatccgccc gtaggtgggc
    16681 caggcccgga ccaacgcctc gggtggcatc ctgctggccg cgagcagttc gtcggcccag
    16741 gccaggaaca gatcgccgag caggatcgcg gccgagcggc cgaagtcggc gggatcaccc
    16801 cgccagccgg cggtccggtg gacccgggag aagcgccggt gcgcggccgg cctgccgcgc
    16861 cgtgtgtcgg aggcgtccat gacgtcgtcg tggatcagcg cgcaggcgtg cagcagctcg
    16921 atggcggcgg cggcggtcac aatctcgtcg cagtccgggc cgcccgcgcc ccgccacccc
    16981 cagtagcaga aggcgggacg caaccgcttg ccctccgcca gcagaaattc ggtggcgata
    17041 cggacgaacg ggatcagatc gtcgtcgatt ccgcgcagga gcgctccgcg cgaaccggcg
    17101 aagcgccgca acacggcgga gacccgccgg cgcacatcca ccgtggtgtg gtccggcacc
    17161 gtggtgtggt ccggcaccgt ggtgtggtcc ggcaccgtgg tgtggtccgg caccgtggtg
    17221 tggtccggca ccgtggtgtg gccggggatt ggccggcgcc cggggtaccg tgcggtgtgc
    17281 ccgtgttcga caccgccgtc gtcgtggtcg ccgttctgct ggtcgccgcc gcactgggcg
    17341 gattgaccct gttgcggctg ccacccgcgg agctgactca cactgtcgac ggtatcgacg
    17401 ccgtggaggt tctggtggcc gccggccgcg tcgagatctc cgggcgggac cgcgaggacg
    17461 tgcacgtcgc gctgaccgtg cggcgtcgtc ccggtcggtc cgtacccgtg ctcacgaggg
    17521 ccgggagcac gctgcggatc gacggccggg ccagcgacgt gcgggtcagg ctgaccgtgc
    17581 cgccacgggt ccgggtgcgg gccgaggtgc tcgccggcga aatcacgctg tggggggtag
    17641 gcggtgaact gtccctggtc acccgcgatg gcaccatcgc cgggcgggag ctcacgcgcg
    17701 gtccggtcgc cgcgcgcagc cgggacggcg acgtcaacct gcacttcagc gaaccgccgg
    17761 acggcgtgcg ggcgcagagc gagacaggca tggtcaccgt catgctgccc gacggcgagt
    17821 acggggtgga ggtggagacc gccgatcccg gggcggccga cgtggagctg accccgtcgg
    17881 cgcacgcggc gtgccaggtg gtggcgcgca gcgtgtccgg gcgggtacgg gtcggtctcg
    17941 ccgcgccgct gggacccttg tctatctgac gtctcttgtc catctaccgt ccatctgggt
    18001 tgtcccagct ggtcccgccc aacgagcccg tttcagccgg gttgctcacc cacgttggtg
    18061 gaatcgacgg atcatgactc tcgcgtgatc acgctgggga ttcatgggat cacgccgggg
    18121 aaatgttgct gcccgctgtc ggggcctgat cggtcgtgtt tccgatcggg ggtccgtctt
    18181 cgatcgtggc cacgctcggt ctaccctcgt gccatggcgg cggtccggag tctgagcacg
    18241 caacccacga cgatgggcga gtacctcgcc accggtcgtg cgtccttttc cttcgagttc
    18301 tttccgccga agacgccgga cggcgagcgg cagttgtgga cggccctgcg ccagatcgag
    18361 gcgctgcatc cctcgttcgt ctcggtgacg tacggggcgg gcgggtcgac gcgcgagggc
    18421 acgatccggg tgaccgagcg gatcgccacc gacaccaccc tcacgccgat cgcccatctc
    18481 accgcggtca accactccgt cgccgagctg cgccgggtca tcggcaacta cgccggcgtc
    18541 ggggtgcgca acgtcctggc cctgcgcggc gacccgccag gggatccgca gggcacctgg
    18601 accgcccatc ccgcgggcct gcggcacgcg gacgaactcg tgcgcctggt gaggtcggtc
    18661 ggcggcttct gcgtcggcgt ggcagccttc cccgacaagc acccacgatc ggtcgacttc
    18721 gacagcgacg cgcgctacct ggtgggcaag ttcgacgccg gcgcggacta cgccatcacc
    18781 cagttcttct tcggcgctga cgactatttc cgtctcgtcg accgggtccg ccggctgggc
    18841 tgcgacaagc cgatcattcc tgggatcatg ccggtgacga acgtcgcgca gatcgtccgg
    18901 atggcgcagc tgtccggcgc ggccttcccg ccggcgctgg cctcccggtt gcaggccgtc
    18961 gccgacgacc cggcggccgt gcgggcgatc ggggtcgagg tggcgaccga gttgtcccgt
    19021 cgcctgctgg acggcggtgc accgggcctg cacttcatca ccctcaaccg ctccagcgcc
    19081 acccgagaga tctaccaggc ggtccgatag ccggccgcgg tccgcggggt ggccgatccg
    19141 cggggtgtcc cggtggcgca tgacgggtgg gccgctcgcc tgacccgtcc gcgctcatgc
    19201 cgccgggccg gcactcagtc gtgctcgtcg taggcatcga agacgcacag cagccattcg
    19261 tcgcggagcg aatgctcccg gaccagcgcg aacccggcct ggttggcggc gtccaccacc
    19321 gccgtcacca ggctgagatc aagggtgttg aagatcgggg tgatccgtac cgcaaggatc
    19381 acctggtcgc gatgggcgga gaagaccgcc cgcgggtcga ggtcctcaag ggtctccact
    19441 acgccgccta cctgttcgga cacgtcactc ccgccacgtc tgggtggcac cgctgttctc
    19501 tcgtgacacc gctgttcctc cgacaccgcg tctccccacc tcgggccggt ccggtgaccg
    19561 atcgacgcct tcggttttgg tcgccggccg gacgcagggt gccgctacgg ctcgcggtag
    19621 gggacgacga gactctatgt cccagcatgt cccagcgcga gacggcgtac cggacggatg
    19681 gcggcgtacc gggcggggcg ctggccgtac cgggcggaac gggatggcgg aacgggatgg
    19741 acgacgggca cgatggacga cgtgagcacc ccgctacccg gtcgggacac ctaccttgcc
    19801 caatggtcgg ccctgcacgg cggctacgac ctggcgcgcg ggctatggct cgttcgtgcc
    19861 tggttgacgg tggtctactg gctggccagg ccgctcgccg cccgccgggt gcgcccgtcg
    19921 gcggtgaccg ccgggggggc cgtgctcacc gccctcgcga ttcccccggc cgtggccggt
    19981 ggccggtggc cactgctggg ggctctggtg atcgtgctca gtggcctggc cgacaacctc
    20041 gacggagcgg tggcgattct cacccgacgc gcgagcgcct ggggatatgt cctggactcc
    20101 gtcgtggacc gctgcggtga cctggcctac ctgctggccc tgtggtgtct cggcgcaccc
    20161 ggcggcctcg tgatcgcggc aggcagcatg ctgggactgc tggagtacac ccgggcccgg
    20221 gccggcaacg ccggcttcga cgagatcggt gtggtgaccg tcggggagcg gccgacccgg
    20281 atcatcatcg ccgcggttgg ctcgttcgga gcgggtctgg tgcccggcct cgcgaacctc
    20341 gccgcgagta tcgcgacgac cgcgacgctg gcggtctgcg ccatcggcct ccttcagctc
    20401 acggccacgg tccacgcggc cctgaccgcc gggtcaggcc gggccgatga gaccggcgac
    20461 gatgccggcg gagagcacga cgagcggcag cccgccgccg ggatgggttg acccaccgac
    20521 gaggaacagg ccgggtaccc gggatgcgtt cggaggccgc aggaaggccg cccgcacgcc
    20581 gttcgaggat ccaccgtaga tggatccgcc caccgtcccg gtgcgccgtt ccagatccgc
    20641 cggggtgatg gtctcgtacc agcgcaaccg ggagcggacg tcgaacccgc gggcggcgag
    20701 cacgtcgagg atgcgccggg cgtagccgtc ggtgagcccg ggacggtccc agtccagggt
    20761 gcctgcgccg ttgtggccgc ccgcgccgcg atgcgggggc gcgttcacca ggatgaacca
    20821 cgcctcgcag cccggcggcg cgcaggccgg gtcggcgggc gcggcaagat agatagtggg
    20881 atcggccgcc agccggcccg cgaagacggc atcgaactcg gcatcgtagt cggcggggaa
    20941 ggtgaccgtg tgatgcccca gcccgggcgt gcgacccgtc agggccagca gcagcacgaa
    21001 gccggacatc gacggtacag tccgccgcag ccgccggcgg ccgacccgat cgttcaccag
    21061 ccggccgtag agcgccgccg cgtcggcgtt cgcgacgacg acgtccgcgg gcagccggat
    21121 accgtcggcg agacggaccc cgtcgacccg gccgccgggg gtccgggtca ccgccagcac
    21181 cggcgcgtcg agcaggatcc ggacgccgcg ttcctcggcg cggcgggtga gcgcatcccc
    21241 gaggcggcgc aggccgcccg cgacgtacca gcccccgaag cgccgttccg cgtggaccac
    21301 cgacaccaga gcggcggggg cgtgccgggg atcggacccg gagtaggtgg catagcggtc
    21361 caggatcatc cgcagccggg gatcacgcag gtagcgcagg cccagccggc gcaggctccg
    21421 gccgggcgcg atcgcggcga tgtcaccggg tgcggaccag gcgagccgaa ccagcccggt
    21481 cgccgacacg ggactggaca ggaacggtcc ttcggcggcg tcgaagaccc ggcaggcccg
    21541 gtcggcgagc cgccgccagt cctcgcccga cccgggggcg atccgatcgt ccagttcggc
    21601 cacgaacgcg tcgtcgtcgg catgtgcggc gagcgtcgtg ccgtcggcga accggtagga
    21661 cgcgatcggg tccagccgac gcagctccac ctcgccgcgc aacggcccgc cggtcgcggt
    21721 gaacaggtcc tcgaacacgc cgggcatggt cagcagggac ggaccggtgt cgaagccgaa
    21781 cccatcgcgc tcgtaccagc cgagcttgcc tccggtccgc gacgactgct cgcagaccgt
    21841 cacgtcatgc ccggtggcgg cgagccgggc cgcggccgcc agcccgccca caccggcgcc
    21901 gatcaccaca acacgggcca tgcgacgact gtacgagctg ctccttcccg gttatccacg
    21961 aggaaggaaa cgggcatcga agcctcggga agaagaagga agccgccgga ggggcaaggg
    22021 aagctcctgg cggggtgcgg ggtgcggggt gcggggtgcg gaccagtggt caggggcagc
    22081 gggtaaccgg tcgtcccttc catcgggcgg taccccgccg acgacgccac cacgacaccg
    22141 cagtcaggta gcccaacagg ctcacggaag ccggatgagc ggcggcgtcg ggccagctcc
    22201 ggccgcccgt gcggcgggcg gcgagcaccc ggccggcgac cccggcgagg tacccgaccg
    22261 cgcccgggcc cgagccaccc agtgccgcca ccgccggcac gacgaacagc caggccagca
    22321 tgccgatctg cccgacgctg ccgagcgtgc ttccaccggc gacggccagc gacttcgcgt
    22381 agccgtcccg cagctgtgac catccggagt acatccggtt gaccgcgaga tcggtgccgt
    22441 ccacgaccac tccccgcccg ccggcacgct tgagcctgcg cagcagggcg acatcctcga
    22501 tgacctggtc ccggacaccc tcgtggccgc cggcccggcg gtaggccgcc acgtccacgg
    22561 ccagcagctg tccgcccgcc gccgaaagcg acggccgggc ggagcgttcg gccagccgca
    22621 gcggcagcag cgccagccac gaccactgga gcaggggttg gatcagcctt tcggcgacac
    22681 cggccgcctc ctgacgcggg tagggcgaga cgaggtcgag gccggcgtcc cgcaggagga
    22741 gaacggtccg cgcgacgccg tcgggggcca ccgtgacgtc ggcgtcgacg aagacgagga
    22801 ccgtgcctgt ggccgccgcc gcggcccggg cgcaggcgtg cggtttgccg agccagccgg
    22861 cgggcggctc cgcaccgcgc agcgcgacga tccggttgtc cctcgccgcc caccgcgcga
    22921 ggatctcccc ggtgccgtcg gtggaaccgt cgtcgtagac gaggatctcg aggtcgggca
    22981 cccaccgtga gccgagcagg gccgacaggc accgcggcag gctcctggcc tcgtcgcgga
    23041 cgggtagcac gaccgtcacc cgttcgcgta ccggccgggc cggcggtggg acgcgtagca
    23101 gccgcgcgtt caccgccgtg tgcacggcga tggcggtgga cgccaccgcg gcggaccgta
    23161 ccgcacccga ccagcatcgc ccggcaagcc accgggccgg ggatctcggt accgtccggt
    23221 gcctcgtccc gtgccctgtc cgccacggcg ccgtcatcgt ggtggggagc ccgccgggac
    23281 cgggcggtcc ccggcccggg cacggtcccg gggtccggcc cgggccgccg cgacgagcgc
    23341 agcccccatc gcgatcccgc cggccgcggc cacaccggga cggtcgaaga aggtgaggtt
    23401 cgccagcgtc gaggagacgt aggcccacag gagaagggcg agcggggcgc gctcgtcgcg
    23461 agccgtgctc ccggcctggt ccggaagcgc cgtcaacgcc gcggtcatgg cgatcgcgac
    23521 ggccacccag ccggcggtgt tggtgagtgg gattccgttg agcgtcgggc cgccgccgag
    23581 ccaccgccag taccccgcgg cgaccatctg cgggtcgatg aaaagatccc aggccgcgag
    23641 gacgagcgcg gccagcacga cggtgcgcgc ccggccgcgg tggtggcgac gggccaggac
    23701 atacgccggg taggtcgcca tcgcccaggc catcggcacc acgaccggga cgccgtacag
    23761 gcgggtgccc agggcggagc cgtagacgta gcggccgaag ggccagccgg tgtgcacgcc
    23821 cacggtctcc acgagcagcc cgccgccgac ggtcacggcg agaaacccgg cggtccacgc
    23881 tcggccacgg gtgagcaggg cgtggctcac cgaggaggcg aagaacagca cgatcgaggc
    23941 gatggcgagc gccgccccgg cggatccggt gaccaacgga caggggagct gcaccgccac
    24001 ggtggccgcc gcgaagatcc acggcaccgc ggtgggccgc gccggccgcg ccgatccggt
    24061 gaagagcgcg tcggcggtca tcgtaccggt gcgtgccggt cggctccttg ggcggaggca
    24121 gcgtcgggac gggcggggga gcgtccgcgg agctccttgc cgagcacggc gtagggggtg
    24181 agggtcccgg ggaactggaa gtcggacaac aatggaacga atccctcatg atcgtacaac
    24241 cggcgcgccg gactgcccgg gggttcgagg gcggacagcg cggccgtgcg ttgcggggcc
    24301 ccgcgcagca gctcccgcag tatggtgcgc ccgatcgccc ggccctggta ggcgggcagg
    24361 acgtgcagct ccacgatctc gagacagtcg tcgagccagt acgcggccga gtccggcggg
    24421 agcgcgccgg cgacgacgtc gtgccaccac tggccgaccc ggccgggcag ggcgtaggtg
    24481 atcccgatga gttcgtcgtc gggtgtgacg gccgccacgg cacgaaggtc ccgccgctcg
    24541 aagtgccggc gcgcatgggc ggcccggtcc cgggcggccc gctgcgggtc aggctcgtgg
    24601 tgatcgagga aagcggcctt gtagaccgcg atgacatcgt cgagccgggt gcgcatccgg
    24661 ctcggggacc agcggaccac cctcacgtcc acgtcggtca ccggcgtcgc ctcctgtccg
    24721 cgcccggatc gccgacctgg ccccacgagt cgggtccggc gagccaggag gctggggcgc
    24781 accatcacgt cgctcgacga taactcgccg cccgccggca ccgctcggcg atgggaatta
    24841 ctgctacgta acgtcattcc actgatgtgg agggtgctaa ctccggatgg gtgggagacc
    24901 ggcccgatca ccggccatgg cgagcgtggc gcagcgcggc gtgccggcga ggaggtcggc
    24961 caccagcatg gccaccgccg gggcctgcac ggtgccaccc gcgttcgtcc ctgccgccac
    25021 gatcacccgg ccgccgtggt ctgccacggc ctcgacaagg gggaggccgt ccggggtcgc
    25081 cgggcgctcg cagacgcgga cgtcgagcat ctccacgctg ccgtcaggcc ggcgcagcgt
    25141 cgggaacagg ccggcgaccg cctgctcgaa aaccgcgcgc agacgggcga cgccgctgtc
    25201 cgcggccgcc cgcacggcgg tgcccagata cccgaatccg ccgctgacat ggatcctggc
    25261 accatcggcg gacagcgtca cattgatcac acctagggga tctccggcgt ggaccttcac
    25321 cggccgtcgc agacccgggt tcggcagggt cagcgagagg ccgagcagat gcgcgacggc
    25381 accggcgccg ggccaggcgg cgcccagcag ccgctgcagg tcgcggccgg ccacggtcac
    25441 cacggcccag ccggtgcgca gggtcgagcc gtccgcgaga tgcagccgga ccccgctgcc
    25501 ggctccgttc ccgatttcgt gcccggcctc gttcccgttg ccgtcggggt tcccgtcgag
    25561 gttcccgtcg atgtcggtct cgatgtcggt ctcgatgtcg gtctcgatgc gttccacccg
    25621 ggtgccggcg cgcacctcga cgcccgcggc ccgcagccgg tcgatgagta ccgtggccag
    25681 atcgtggatg ttgaccgcgt agccgtccac ctcgaccgct gcggtcacct cccggacgcc
    25741 gtcgggcagc gggaccgagc ggcccagcgc gggccagtcg cgaaccaggt ccgcccggga
    25801 caaccgaacg acccgccccc ccgcggaccg ctgcagccgc tcgcccgcgg cgaggtcgtc
    25861 cggaccgaga tagatccgcg ggatgcgggc gtcccagcgc aacccgcacc cggcagcgag
    25921 cccgtccccg ccgtcggcga gcgcgaaaag atgctcccac ccgcgcaacc ccagccggtt
    25981 cagggcgatc accaggtccc gggccaccgc gtgcagcccg ggacggtcgg cgcactgctc
    26041 gaaggcgccg gcccaggccc tctccggctc cgacagcgac tccgggtccc gtagccgcca
    26101 gccgccgtgc gtcggatcgc gatcgaggac acccgcgcgg ctcgcgtccg cctgcggcag
    26161 ggtctcggtc gccgacaggt gccgaccgtt cgtccccgcg aacgtcgtgc cctgggcggc
    26221 agggtctgcc cggtcggcag gcgcggcgtc gaggacccgg acggggtggc cccgcagccg
    26281 cagcacgagc gcgatcgtga gtccgacgat cccgccgccg acgaccacca cgtcgtgctt
    26341 gtcgacggcg gaaccgtcag aggccgggtc ctcgacggcc cggcggccgg tgccccgccg
    26401 atcgccccgg cgatcggcca ggtcatgacg atcgtccttc gggccgttcc cggtgaggcc
    26461 gttcccggtg aggtcgttcc cggtgaggtc gttcccggtg aggtcgttcc cggtgaggtc
    26521 gtccaggtcg gcccgtccga ccaccgcgag gaacgcctga tcgagatcgt tgctgcaggc
    26581 gggactgtgc atcgccacgg agcagagagt gaatccgcgc cgcggctccc cgccgtcctc
    26641 ggcgatccgc cccgcgagca gctcgcggac cgggccgagg aaccgggggg cgttgtcgat
    26701 cacgacctcc aggtcgcggc ggtcgtaggc gtcgaccagc gcccggtcgg tgaagacgtg
    26761 cggttcgctg accgacacga gtcggcggcc ggtgaacgac ttgacgtgcc gcatgtcgat
    26821 catgcccgcg gatatccggg gcccgtcgtg cacgaggggc gcggcgatgc tgatcagatc
    26881 ggcggcgtcg aggacgtcct cgacggtgcg ggcgacgtgg atccggtcta ccggcagtcg
    26941 gtgcttcgcc gcccagagcg cgaccgtcgc cggcctcgcc gcgagtgagg gagcgtgcac
    27001 ggccaggtgc cagccgcgtg cgacgccctc ccgggcgacc cggctgttga tgtttccggc
    27061 gccgacgagg ccgagcacgc ccggccgatc ggtgcgcgtg gcggccccgg ccgactcggc
    27121 gccgggtgcg tggccgagcg ggtcgaacag ccggtcgacg atgaaccggg cgacgtg
//
