LOCUS       NC_007777              25326 bp    DNA     circular CON 05-SEP-2024
DEFINITION  Frankia casuarinae, complete sequence.
ACCESSION   NC_007777
VERSION     NC_007777.1
KEYWORDS    RefSeq.
SOURCE      Frankia casuarinae
  ORGANISM  Frankia casuarinae
            Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
            Frankia.
REFERENCE   1  (bases 1 to 5433628)
  AUTHORS   Normand,P., Lapierre,P., Tisa,L.S., Gogarten,J.P., Alloisio,N.,
            Bagnarol,E., Bassi,C.A., Berry,A.M., Bickhart,D.M., Choisne,N.,
            Couloux,A., Cournoyer,B., Cruveiller,S., Daubin,V., Demange,N.,
            Francino,M.P., Goltsman,E., Huang,Y., Kopp,O.R., Labarre,L.,
            Lapidus,A., Lavire,C., Marechal,J., Martinez,M., Mastronunzio,J.E.,
            Mullin,B.C., Niemann,J., Pujic,P., Rawnsley,T., Rouy,Z.,
            Schenowitz,C., Sellstedt,A., Tavares,F., Tomkins,J.P., Vallenet,D.,
            Valverde,C., Wall,L.G., Wang,Y., Medigue,C. and Benson,D.R.
  TITLE     Genome characteristics of facultatively symbiotic Frankia sp.
            strains reflect host range and host plant biogeography
  JOURNAL   Genome Res 17 (1), 7-15 (2007)
   PUBMED   17151343
REFERENCE   2  (bases 1 to 5433628)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Goltsman,E.,
            Martinez,M., Schmutz,J., Larimer,F., Land,M., Kyrpides,N.,
            Lykidis,A., Francino,P., Benson,D.R., Huang,Y., Mastronunzio,J.,
            Bickhart,D., Niemann,J., Rawnsley,T., Tisa,L.S. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2006) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000013345.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 02:41:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,755
            CDSs (total)                      :: 4,702
            Genes (coding)                    :: 4,516
            CDSs (with protein)               :: 4,516
            Genes (RNA)                       :: 53
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 53 of 186
            Pseudo Genes (incomplete)         :: 162 of 186
            Pseudo Genes (internal stop)      :: 10 of 186
            Pseudo Genes (multiple problems)  :: 37 of 186
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:46:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1328465
            Orig. end                         :: 1353791
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000249.1.
            URL -- http://www.jgi.doe.gov
            Source DNA and bacteria available from Louis Tisa
            (lst@patia.unh.edu)
            Contact: Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25326
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="4"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25326
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25326
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15326](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15326)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    224..238
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            289..1035
                     /locus_tag="FRANCCI3_RS23215"
                     /old_locus_tag="Francci3_1115"
     CDS             289..1035
                     /NRPS_PKS="Domain: PKS_AT (1-183). E-value: 8.5e-49. Score:
                     158.4. Matches aSDomain:
                     nrpspksdomains_FRANCCI3_RS23215_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="FRANCCI3_RS23215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1115"
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_011435563.1"
                     /sec_met_domain="PKS_AT (E-value: 6.7e-47, bitscore: 158.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIACRRSALLRRISGRGALATTELSPAQAHAVADASAGRISVAGE
                     NSPRSTVLAGDAASLARLVDDLTRRDVYCRVITGTVASHSHYVDDLRADLDLALRSLAP
                     GPTRIVMYSTVTGEPVPGTSLASQYWMRNLREPVRFAAAVERLGDTGHEVFVEVSAHPV
                     LLSPVRQTLAHAGRPAHLLASGRRQAERRSVLASLGMLYGCGREPRWAAFALSEPGATL
                     TPYQAAVLGAVRLTRPASQLETSPAL"
     aSDomain        292..837
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: False, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRANCCI3_RS23215_PKS_AT.1"
                     /evalue="8.50E-49"
                     /label="FRANCCI3_RS23215_PKS_AT.1"
                     /locus_tag="FRANCCI3_RS23215"
                     /protein_end="183"
                     /protein_start="1"
                     /score="158.4"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="IACRRSALLRRISGRGALATTELSPAQAHAVADASAGRISVAGEN
                     SPRSTVLAGDAASLARLVDDLTRRDVYCRVITGTVASHSHYVDDLRADLDLALRSLAPG
                     PTRIVMYSTVTGEPVPGTSLASQYWMRNLREPVRFAAAVERLGDTGHEVFVEVSAHPVL
                     LSPVRQTLAHAGRPAHLLA"
     CDS_motif       418..456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS23215_0001"
                     /evalue="2.10E-03"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="FRANCCI3_RS23215"
                     /protein_end="56"
                     /protein_start="43"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GENSPRSTVLAGD"
     CDS_motif       541..567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS23215_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="FRANCCI3_RS23215"
                     /protein_end="93"
                     /protein_start="84"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="SHYVDDLRA"
     misc_feature    583..585
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       664..708
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS23215_0003"
                     /evalue="2.40E-06"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="FRANCCI3_RS23215"
                     /protein_end="140"
                     /protein_start="125"
                     /score="19.3"
                     /tool="antismash"
                     /translation="ASQYWMRNLREPVRF"
     CDS_motif       751..780
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS23215_0004"
                     /evalue="7.30E-04"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="FRANCCI3_RS23215"
                     /protein_end="164"
                     /protein_start="154"
                     /score="11.9"
                     /tool="antismash"
                     /translation="FVEVSAHPVL"
     gene            1098..1727
                     /locus_tag="FRANCCI3_RS05570"
                     /old_locus_tag="Francci3_1116"
     CDS             1098..1727
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435564.1"
                     /locus_tag="FRANCCI3_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1116"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_011435564.1"
                     /transl_table=11
                     /translation="MSREESRELTREKLLRSAAELFAERGLAGTSVEQIVERAGFTRGA
                     FYGNFDGKHELVLALLEKRTERELEELRALGRDAGSFEGMVEQFRAWHRERDRHLASWL
                     VLRTELWLYGLRNPGVLPTLTDREARTRTIIAEALARDFTSRDASPPAPVEVLALIVHA
                     LDDGLAIQRVLSPESSPDDAAVDAVDLLLRSWVALGREIAAEKGND"
     misc_feature    1668..1670
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1727..2071
                     /locus_tag="FRANCCI3_RS05575"
                     /old_locus_tag="Francci3_1117"
     CDS             1727..2071
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039377.4"
                     /locus_tag="FRANCCI3_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1117"
                     /product="DUF6204 family protein"
                     /protein_id="WP_011435565.1"
                     /transl_table=11
                     /translation="MPEHVYRVLVRGRFDKLDPPAREKLRRNADQQDVLNASFTEEGTL
                     VYNESIVAFTFRLVVRVEFDDKAEQRAQDAAEERLMARFDEIGCGYRDLRFGVTDMDSM
                     KINRPARERR"
     gene            2099..3514
                     /locus_tag="FRANCCI3_RS05580"
                     /old_locus_tag="Francci3_1118"
     CDS             2099..3514
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435566.1"
                     /locus_tag="FRANCCI3_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1118"
                     /product="MFS transporter"
                     /protein_id="WP_011435566.1"
                     /transl_table=11
                     /translation="MVDTERTTWPSEPVLQVAQPAPDPRRWWALAVLLVATFMDLLDNN
                     IVTVAIPNIQQHLGASPTSIQWMNAGYTLAFAVMLITGGRLGDIFGRKRMFLTGVAGFM
                     AASGMCAIAQSPEFLVGARVVQGGAAAVMVPQVLAIIHVSFAREEVGKVVSLYAGIVGL
                     AIVAGPLVGGLLLQWNPFGLEWRSIFAVNLPVGAVALVAVSAWMRESRSPNARRPDGIG
                     MILVAVGLLLVLFPLVQGRELGWPMWSIVAMVIAVPVFALFLRYEREKVRRDDSPLLAL
                     NLFKTGSFSVGVGTQLLFSCVPAGFFITWTVYLQGGLGWSALHTGLTTIPFSVAVPVAG
                     GLAVRYIFPKYGRRCLMVGVAVMTSGVLSYVWTAHHFATTVTAWHAAPSLLLIGSGMGL
                     LVAPLTGMILIDVPPHEAGAASGIINATGQLGAAVGVALIGGLFFSQGLGKFAGKQTFG
                     VVWGFQWGCVARF"
     gene            3600..4772
                     /locus_tag="FRANCCI3_RS05585"
                     /old_locus_tag="Francci3_1119"
     CDS             3600..4772
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011434857.1"
                     /locus_tag="FRANCCI3_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1119"
                     /product="ISAs1 family transposase"
                     /protein_id="WP_011434857.1"
                     /transl_table=11
                     /translation="MPAAPVLPPAPVLDRLAAVGAGNQPPSPAGLLAVFNQLPDPRKPR
                     GRRHSLAAVLTLATCAVLAGARSFTAIGEWSADAGQAVAGLLGVSRVPEESTFRRVLAA
                     LDADALDTALGAWAAAATTPPAGTRRRLAVDGKTLRGSRTPDSPGRHLLAALDHTSGVV
                     LGQVAVDAKSNEIPALPVLLADLDLTDVIVTADALHTQRQTASWLVSRHAHYILTVKAN
                     QPALYAQLAALPWRRVKTAARTVERGHGRRERRTVKTTEVRAGLLFPHAVQAVQVTRRR
                     QPLADGPATTEIVYLVTSLPTHQASPTLLATYAREHWLVENRLHWVRDVTFGEDLSQVR
                     TGHAPQVMASLRNLAIAILRLTGATNIAQAIRHHARRPERPLETIKSLAC"
     misc_feature    3618..3620
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4782..5141
                     /locus_tag="FRANCCI3_RS05590"
                     /old_locus_tag="Francci3_1120"
     CDS             4782..5141
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Francci3_1120"
                     /product="hypothetical protein"
                     /protein_id="WP_011435567.1"
                     /transl_table=11
                     /translation="MPGPWFFSALATGEPARTDRVTSQVQQALVSQGHSSGEVTRLMAE
                     LRRCDIHQPDLSLVPADCGGRVSVTDRGSLTNALAKVRAEEFVSGFVKTLWWIVGALAV
                     VLCLLFLLPARRGGP"
     gene            complement(5308..5685)
                     /locus_tag="FRANCCI3_RS05595"
                     /old_locus_tag="Francci3_1121"
     CDS             complement(5308..5685)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435568.1"
                     /locus_tag="FRANCCI3_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1121"
                     /product="DUF3037 domain-containing protein"
                     /protein_id="WP_011435568.1"
                     /transl_table=11
                     /translation="MQGKAHYALLFAVPRVDRGERINVGVLLYSPAAEFLAAAINVDTE
                     RLRALDSNADVELIQAALNFIQMVCAGDPAAGPAATRSARARFGWLTAPRSTVVQPGAV
                     HGGITAKPEVELDRLMDRVVR"
     misc_feature    5692..5705
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            5813..6646
                     /locus_tag="FRANCCI3_RS05600"
                     /old_locus_tag="Francci3_1122"
     CDS             5813..6646
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435569.1"
                     /locus_tag="FRANCCI3_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1122"
                     /product="IS5-like element ISFsp7 family transposase"
                     /protein_id="WP_011435569.1"
                     /transl_table=11
                     /translation="MSFTYTAELPFGDHTVFRLAGLLVAERQRRGTRKGTRTLSALEQA
                     VMVLRWFCDGTRARRLFSDHGVSRSVGYRYLHEGVAVLAWQAPDLREALMRARVAGYEH
                     LIVDGTVIETDRLRMPGPTEGVDLWWSGTISNHGGNIQVLSAPDDGWPLWVSDVRPGRE
                     HDSTALKASGALPVLAEWTADLHEVLFDLGYEGLGNPAGPLATAYKKPKGGTLTDEQKA
                     HNRIHNALRAVGERANALLKGTFRLLHNITIDPWKIGLVVKAALVILHTEHRRTA"
     gene            complement(6989..8266)
                     /locus_tag="FRANCCI3_RS05605"
                     /old_locus_tag="Francci3_1123"
     CDS             complement(6989..8266)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006503528.1"
                     /locus_tag="FRANCCI3_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1123"
                     /product="hypothetical protein"
                     /protein_id="WP_011435570.1"
                     /transl_table=11
                     /translation="MATRRGLFAELQYQAAQAEKRQRQQRAAAHRALLAAEKEAAQKAR
                     AAERAAAAAAKASTKEQARLLKEAGLLYVAARLSEVGSLNADLASTFEEIDGILATALL
                     VDSYVDLEALKVTTVVHPPFEPGALAVPTPPVAAPVYPAEPVYQEPQVPGVLFGAKKKH
                     AQAIAQAQTTHEQALRRWREQVSAIRTAHVSALEQRQRAEDARLAKLAAARAVHVEACR
                     RRDADADERNRGLTRLINDLAFDVEAAIREYVGIVLSNSAYPDAFPVTHDYEFDLSSRE
                     LRLAAAVPEPSAVPSVKEYKYAPRKDEISSTKLPATVQKDRYASAVFQTAVRTLHDVFG
                     ADRQGKIHSIALTVGVDRISPATGLPETIPLAIVAADRATFRKFRLDQDEIVPQKTLEY
                     LGAALSPSPFTLKPADASRGIRQRGQ"
     misc_feature    complement(8349..8363)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    8349..8364
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            complement(9099..9962)
                     /locus_tag="FRANCCI3_RS05610"
                     /old_locus_tag="Francci3_1124"
     CDS             complement(9099..9962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435571.1"
                     /locus_tag="FRANCCI3_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1124"
                     /product="hypothetical protein"
                     /protein_id="WP_236701472.1"
                     /transl_table=11
                     /translation="MRAAHERASAALRVTVDRTQAEEAWGFAGRTLGRPVMTPDSPGWL
                     RIAATEAGQQITTFWDGGRTAQQALPASIPRPALRAIHDHHHDGWDYRAELYDRVHVRP
                     LAVTTVPRRLTDSPKGQWFQALRRSFRILATVSTDRRTIEQSYLDDVMPRILGEPITTT
                     SPAPWVTAHGDLHWANLCGPTLCMLDWEGWGLAPAGYDAATLYCHSLFMPTLAAQVQAR
                     FADALSTESGRYAELAVIAELLDTVHSGTGLDIDHAGLLRIRATHLLRRGIPRQQEGAA
                     TRPGQT"
     misc_feature    complement(9183..9185)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11041)
                     /locus_tag="FRANCCI3_RS05615"
                     /old_locus_tag="Francci3_1125"
     CDS             complement(10001..11041)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435572.1"
                     /locus_tag="FRANCCI3_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1125"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_011435572.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.5e-50, bitscore:
                     168.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPADPLTVPSRDIGTEQAVLAVLAGIPLPTAAAHAALPPDQLAAA
                     VATYQAAGRAALAVQGAAWFQVRVTFPEPADAETVAATHLAPVLRHAQAAGAVASWWFV
                     RKSPDWRLRLSPASGQSVADLRATLRSAFDDLTAAGTIPTWAEGIYEPEEYALGGEVGT
                     DVAHRLFTADSGHVLDRIHSEITSRTPPTLGRRELSMLLIGTLLRTAGLDWYERGDVFN
                     RVSRLRPPPATSPTAAEIQRLATALRRLLTTDTDPAGDLFGADRPLANLGIWASAFHNA
                     GRALGQAAYAGTLRRGLRDVLGHHVIFHWNRLGLNAETQGVLAATARETILRAPALPEA
                     LTPQAR"
     gene            complement(11023..12240)
                     /locus_tag="FRANCCI3_RS05620"
                     /old_locus_tag="Francci3_1126"
     CDS             complement(11023..12240)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435573.1"
                     /locus_tag="FRANCCI3_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1126"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_011435573.1"
                     /sec_met_domain="LANC_like (E-value: 2.8e-45, bitscore:
                     152.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIACDQAAATAASLATRLTVPSPRELGQTAQSLADGAAGIALLHA
                     ERAHASAERWEPVQAWLTAAISGHLSVAMNSSLYAGAPAVAFAVHIAAGQTRRYTAART
                     ALDQAVATIAHRLVDAANARIDQGEPGRFTEYDVISGLTGIGAHLLAHTPGDDALGRIL
                     TYLVRLTTPLNLDGEELPGWWCSHDPSQGNTAEFAGGHANLGMAHGAAGPLALLSLATR
                     AGIRVHGQTNAINALCAFYDQWRHDSPSGPSWPQWITRADQQAARPAQPGPARPSWCYG
                     TPGIARALQLAGIATGDTTRQNAAEQALAACLTDSTQLAHLTEAGLCHGWAGLYQTVAR
                     AAADATTETLSRHLPTLAASLLLCALSSSGRADGLLEGDAGIALVLHSVATGAPATGWD
                     RCLLIH"
     gene            complement(12237..15326)
                     /locus_tag="FRANCCI3_RS05625"
                     /old_locus_tag="Francci3_1127"
     CDS             complement(12237..15326)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018635957.1"
                     /locus_tag="FRANCCI3_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1127"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_011435574.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9e-187, bitscore:
                     620.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1e-11,
                     bitscore: 43.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.8e-26, bitscore:
                     89.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRSLDVPLLRMAVVPTDVDLPPWPDLDDTTDGAVAGWTDWLRDI
                     WARPVFADAMRLASPSLAARVASVFDGQCHDRRTARRAVTATARYVLRMTGRATPFGLF
                     AGVGPADFGPRARVRLGDDHRVHARPGGAWLAALADDLEAFDTLLRRLPVTADGIPVAR
                     GDRLFIGPVARSGDDAGPESVVEVSVRRTRAVEAALLHAVSSLPVPELVARLAADKPAP
                     AAGQIETMVIELVRRRFLHTPLRPATTITDPLSEVADQLAAARIDDLPPLAGRLNVIRD
                     LQDLLAHHDNTRSASHRRTLRTQAETLQRRVVPSADPDLDVGLVLNADVVLPAAVAEEA
                     GAAARALARLTGPTAVPPEWADWHEAFLERYGPAALVPLLEAVNPDTGLGLPATFRGST
                     RSHRPRGNAARDQRLAALTQRAALDGALEARLGDAAIAALAGDTAPDRVPPHAELIAEV
                     HANDLPALSRGLFTLRVTGGGRAAATTTGRFLHLLDPASFDRFRDIYAALPTMRAGATA
                     AQVSCPPLPAATVGVARSPRLTDTVITLAEHHDAGPCVLRPADLAVGADAEGLYLVSLP
                     DRRLVEPSAAHAVEFQYHTHPLTRFLCELPTARVAVSIPFSWGAAGGLPFLPRLVHRRT
                     VLAPAHWNLTAADLPSRAESAQEWREALARWGGTIPVPTRVQLVETDNRLRLDLHVDAH
                     LALLRDHLHRHGSARLDEDAAPEAFGWLAGHAHELVIPLATTAAPLPGPAPERLAATVP
                     AARSDAQLPGVSPWLSARLYGHPDRATDLLARLHDLLDAWPDPPAWWFLPYRDTEPHLR
                     LRLAVNEPGGYGLAATRLGTWAAVQREAGLLSHLHLDTYQPETGRYGYGPAMTAAEGVF
                     SADSAAALAARRLAASARLSVGALTVAGLVDMAIAFTGALSTGMRWLRDVLPHEPARVP
                     RAERTTTLHLANPADSFAHLRAVPGADAVLSAWQPRATALAAYRDALAAQRPPDQALAS
                     LLHLHVVRTLGLNPAAEQTCIALARATAARALATTEATVS"
     aSDomain        complement(14586..14840)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FRANCCI3_RS05625_Lanthipeptide_LanB_R
                     RE.1"
                     /evalue="6.20E-14"
                     /identifier="RREFam001.1"
                     /label="FRANCCI3_RS05625"
                     /locus_tag="FRANCCI3_RS05625"
                     /protein_end="247"
                     /protein_start="162"
                     /score="43.5"
                     /tool="antismash"
                     /translation="RGDRLFIGPVARSGDDAGPESVVEVSVRRTRAVEAALLHAVSSLP
                     VPELVARLAADKPAPAAGQIETMVIELVRRRFLHTPLRPA"
     gene            complement(15351..15521)
                     /locus_tag="FRANCCI3_RS24210"
     CDS             complement(15351..15521)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018635958.1"
                     /locus_tag="FRANCCI3_RS24210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_023840439.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 3.5e-17, bitscore:
                     60.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAHTTAPAPLPLAGDYDLDVEIVDGGPVIPELLRSTSDNCGKT
                     CSSACTSCKQN"
     CDS_motif       complement(15432..15521)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTPAHTTAPAPLPLAGDYDLDVEIVDGGPV"
                     /locus_tag="FRANCCI3_RS24210_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15351..15431)
                     /prepeptide="core"
                     /locus_tag="FRANCCI3_RS24210_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-11.30"
                     /molecular_weight="2602.9"
                     /monoisotopic_mass="2601.2"
                     /core_sequence="IPELLRSTSDNCGKTCSSACTSCKQN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTPAHTTAPAPLPLAGDYDLDVEIVDGGPV"
                     /leader_location="[15431:15521](-)"
                     /alternative_weights="2620.9"
                     /alternative_weights="2638.9"
                     /alternative_weights="2657.0"
                     /alternative_weights="2675.0"
     gene            complement(15570..16793)
                     /gene="fxlM"
                     /locus_tag="FRANCCI3_RS05630"
                     /old_locus_tag="Francci3_1128"
     CDS             complement(15570..16793)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013422664.1"
                     /locus_tag="FRANCCI3_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1128"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_373420615.1"
                     /sec_met_domain="PCMT (E-value: 3.5e-42, bitscore: 142.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRPEPTGKHAPEDLRARLVDDLVAAGSIKTKEVEAAFRAVPRHL
                     FAPEVSLQDAYADDIVRTKQDQHGITVSSVSAPWLQATMLEQAGISPGMRVLEVGSGGY
                     NAALIAELVGPTGAVTTMDIDADVTERAHHCLAAAGYDQVHVVLADAEHGVPEHAPYDR
                     IIVTAGAWDIPPAWTDQLAPDGRIVVPLRMRGLSRTVALTPRDGVLVSLDHQMAGFVPV
                     RGDGAHPERLVQLHDADVGLRFDEQAPELDAAALRAALLAPRVEAWSGVRFGGMEPFDG
                     LLLWLASSLDDYGLLSRARSPTARELVDPVSPIGTPTAVEADSFAYLTLRKVEDGDDTY
                     EFGAYAHGPDAARLAGLVVTQVQAWNRTHRDASPATISVWPATTPAEALPPGRVIAKRH
                     RIVVLSWS"
     gene            complement(16853..17203)
                     /locus_tag="FRANCCI3_RS27830"
     CDS             complement(16853..17203)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS27830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_023840441.1"
                     /transl_table=11
                     /translation="MQPTYGRLHGTDASAGAELPADASAGVSACWSDDSLAFLAFTPTG
                     GTGVEIGVVAYGPDRYRLADLLTHDVRVWDAERRGGPDPTIRVYPTDAGRASAPAGRLL
                     TKPSAQLLITWG"
     gene            complement(17235..17723)
                     /locus_tag="FRANCCI3_RS27835"
     CDS             complement(17235..17723)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.5"
                     /locus_tag="FRANCCI3_RS27835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_023840442.1"
                     /sec_met_domain="PCMT (E-value: 7.1e-25, bitscore: 86.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPASTQASIALLHTAMVDLVLAKEPVSAPVVAALRAVPRDLFLPD
                     AGTEEAYKDDAVVTKWDVYGAPLSAVSRPSTVAATLEQLRVEPGQRILEIGSGGYTAAL
                     LAELTGPTGHVTTIDIDQSVVHRTHACLDKAGYTDVTALINDGYFGFPLRAPYDRLRR"
     gene            complement(17723..17953)
                     /locus_tag="FRANCCI3_RS05640"
     CDS             complement(17723..17953)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018635961.1"
                     /locus_tag="FRANCCI3_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_023840443.1"
                     /transl_table=11
                     /translation="MSVAPTGMPVPAVPRWRRPSTLDPTVPDAVEVALDGHRVLIRSSL
                     GPSVRTTPGAFGDFVRAVKRGEYDDLLGEVA"
     gene            17988..19529
                     /locus_tag="FRANCCI3_RS05645"
                     /old_locus_tag="Francci3_1130"
     CDS             17988..19529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435576.1"
                     /locus_tag="FRANCCI3_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1130"
                     /product="hypothetical protein"
                     /protein_id="WP_236701471.1"
                     /transl_table=11
                     /translation="MEPAEPGPHDSAQARREQKRRHDTTRGSSALSWWNGRDRIGVFTA
                     RSTHDTLRPNGATERNGSLRACNSSLHPPAKASTGRPKVQAGQRNDALANLADLLRTLR
                     DQHRTNNSRLEARTGFKRQQISRAVNGQEIPSADLADALDTALAAAGAIRRLRDEAVRE
                     KRARDLGLDPSRQEEPVDANRRQAFELAAASLVAAQMYREWTSSAPDVLTLDEIDDAIN
                     AHTVAFTVEPHQRLAPKVWKTWKSAHHHLMNGSGRARPQTRLTVAAGYASYMLSRLSFN
                     LGDTLASRRFIRLAEDHASQTDDVVLTASVGEMVTTLAFYGRRYQEAAVSARKTAVVAD
                     NPYTRARIASYEARALGALGDVEGTRAALNRMRTSVTDLPLQPGISPFGPAAAEMMYAG
                     VLTRIGGGVEAEPIARAALAAYEGGQAGGFEDYGHALLALAASLTAREQPEIDEAATMA
                     GKVVDMLDTRPTASVSDRVAEIAIAFTGHPTVEPVRDFWDRWQARPRLELTTGQA"
     gene            19532..20104
                     /locus_tag="FRANCCI3_RS05650"
                     /old_locus_tag="Francci3_1131"
     CDS             19532..20104
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435577.1"
                     /locus_tag="FRANCCI3_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1131"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_011435577.1"
                     /transl_table=11
                     /translation="MTLHYGTPTVVTIPTVLTERLVLRGWKVVDLDPYAAMNADPETMR
                     YLDGTFDRAGTERLVTHLIGMWAIRGHGMWAVEDRASGEFLGRAGTYFAQGWPGVEVAV
                     SIRRDRWGQGLGTEAITAALDFGFAHLDVDELITATHQENAGMNMIARKLGMTFREIAD
                     VGPWKANNVHAISRASWAANRPEESKG"
     misc_feature    20213..20227
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    20702..20720
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.36"
                     /tool="antismash"
     misc_feature    complement(20851..20862)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            21008..21904
                     /locus_tag="FRANCCI3_RS05655"
                     /old_locus_tag="Francci3_1132"
     CDS             21008..21904
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016883343.1"
                     /locus_tag="FRANCCI3_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1132"
                     /product="restriction endonuclease"
                     /protein_id="WP_023840445.1"
                     /transl_table=11
                     /translation="MTSPDVGVPTYDQLLWPTINALRDLGGSGAISEINERVIELEKFS
                     PEQQDQLHGDGPRTEIEYRLAWARTYLKMMGLTDNSSRGVWTLSEPGRSVDRADIPKIH
                     AEAKRAWAAERAEKARKPADSEPKATYEQATSDDGEKDQEIAWKEELLEAVMAMPPDAF
                     ERLARRLLREAGFISVNVTGGTGDGGIDGLGIYRLSLVSFPVFFQCKRYKGSVSPSAVR
                     DFRGAMAGRGDKGLLITTGSFTSAAQKEATRDGAPPVDLIDGDRLCDLLREYNLGVKVE
                     IVQHEKAIVNRRFFDDI"
     gene            complement(22242..22571)
                     /locus_tag="FRANCCI3_RS05660"
                     /old_locus_tag="Francci3_1133"
     CDS             complement(22242..22571)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828129.1"
                     /locus_tag="FRANCCI3_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1133"
                     /product="hypothetical protein"
                     /protein_id="WP_035730000.1"
                     /transl_table=11
                     /translation="MSFDLVSWEGERPADNLAAGSAFNEMFQRYDDDPETPATDLIAAY
                     CEALTHRWPDDDTAPWSVTPQPSGPFLYLCVVWSMAEEVSAYTAELAASMRLVCYDPQE
                     EMLLP"
     misc_feature    22799..22808
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            23079..23627
                     /locus_tag="FRANCCI3_RS05665"
                     /old_locus_tag="Francci3_1134"
     CDS             23079..23627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006541413.1"
                     /locus_tag="FRANCCI3_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1134"
                     /product="HD domain-containing protein"
                     /protein_id="WP_011435580.1"
                     /transl_table=11
                     /translation="MEVAVAERLASELLTPLGDRWRHVQAVAAAAWEVSAAVDPEERDL
                     LVAAAWLHDIGYAPPIGHLRFHPVDGARFLESHDAPKRLCALVAHHSCARYEAEERGLT
                     AELSAWELEVSPVMDALCAADMTTGPQGQRFTFDERIAEILSRYGDGSIVHRSVTRARA
                     DLQATVERTTARLVAVQPR"
     gene            complement(23615..24085)
                     /locus_tag="FRANCCI3_RS05670"
                     /old_locus_tag="Francci3_1135"
     CDS             complement(23615..24085)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435581.1"
                     /locus_tag="FRANCCI3_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1135"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_011435581.1"
                     /transl_table=11
                     /translation="MARIDYFNDPNAPKANSVVPSVTAVVTDEAGRILMVHKTDNNLWA
                     LPGGGMDLGESITDAAVRETKEETGIDIEVTGLIGVYTNPRHVLAYDDGEVRQQFSLCF
                     TTRNLGGELRTSSETKEVKFVAPEDLDGLNIHPSMRLRIDHYLENRATPYLG"
     gene            complement(24091..24879)
                     /locus_tag="FRANCCI3_RS05675"
                     /old_locus_tag="Francci3_1136"
     CDS             complement(24091..24879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435582.1"
                     /locus_tag="FRANCCI3_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_1136"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_232234883.1"
                     /transl_table=11
                     /translation="MADALARRDIGTVFKIYRQWTGATQTQIAAVCGLPQSHVSDIMNG
                     RRQVTSLEIFERIADGIGIPRGRIGLAERPGAVPEPRTEPGSPAADVPSDVVRVYPSRA
                     AVPAELWRTLFAGARHQVDVLVIAGLFLPDGHADFTAVLRRKGAEGVNIRYALGDPDSP
                     AVALRGDEEGIGDGLAARTRITLTYLASLRDAPGIELRLHATTLYNSIYRFDGDMLVNT
                     HVYGAPAAHSPVMHLRAQPGGLFDHYAASFERIWATTEGA"
     misc_feature    24864..24878
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 gcgagctgct ggccgctgag ccggcgttcc gggaggcgct ccttcgctgt gatcaggagg
       61 ttcggcgttt cgccgaattc tcggtggtcg agcagctcgg tttggacccg ccagcgtccc
      121 ggatggacga gatcgacgtg ctgcagccga ccatggtgtc gttgcagatc gccctgacgg
      181 ctttgtggcg cagttggggg atcgtgccgg atgccgtggt cggccacagc atggggggag
      241 atcgcggccg cgcataccgc aggcgcgctg ggcctccgag atgcgataat gatcgcctgc
      301 cggcgcagtg cgctgctgcg ccggatctcc ggtagggggg cgttggccac cacggagctg
      361 tcccccgccc aggcgcatgc cgtcgcggat gccagcgccg ggcgcatcag cgtcgccggc
      421 gagaacagcc cccggtcgac ggtgctggcc ggcgacgcgg cgtcactcgc caggctcgtc
      481 gatgatctca cccggcgcga cgtctactgc cgcgtgatta cgggaaccgt cgcctcgcac
      541 agccactacg tcgatgacct gcgtgcggat cttgatctgg cgttacggtc gctggcaccg
      601 ggacctacga ggatcgtgat gtactcgacc gtgaccggcg agcccgtgcc aggaacgagc
      661 ctcgcctcac agtactggat gcgtaacctg cgcgagccgg tccgtttcgc cgccgcggtc
      721 gagcggctcg gtgacaccgg ccatgaggtg tttgtggagg tgagcgcgca tcctgtcctg
      781 ttgagcccgg tgcggcagac gctggcgcac gccggacggc cggcgcatct gctggcatcc
      841 ggtcggcggc aggcggaacg gcgctcggtc ctggcgtcgc tcggcatgtt gtacggctgc
      901 gggcgggagc cgcggtgggc ggcgttcgcc ctgtcggaac ccggagccac gctcacccct
      961 taccaggcgg ccgtgctcgg cgcggtccgc ctgacccggc ccgcctccca gctggagacg
     1021 agcccggcac tctgataggc tcttgtatct ggatgcacct ctgtatctag aaggagcctg
     1081 tcatcgcgac cagacggttg tcccgagagg agagtcggga gctgacccgc gagaagctgc
     1141 tgcgctcggc ggcggagctg ttcgccgagc gtggccttgc cggcacatcg gtcgaacaga
     1201 ttgtcgagcg tgccggtttc acgcgaggcg ccttctacgg caacttcgac ggcaagcacg
     1261 agctcgtgct cgccctgctg gagaagcgca cagagcgtga gctggaggag ctgcgggcgc
     1321 tgggccgtga cgccggctcg ttcgagggca tggtcgagca gttccgggcc tggcatcgtg
     1381 agcgtgaccg tcacctcgcg agctggcttg tgctgcgcac cgagctgtgg ctctacggcc
     1441 tgcgcaaccc gggcgtcctg ccgacgctga ccgaccggga ggcgcggacg cggacgatca
     1501 tcgcggaggc gctcgcccgc gacttcacgt ctcgtgacgc gtccccacct gctccggtcg
     1561 aggtgctcgc gttgatagtg cacgcgcttg acgacggcct ggcgatccaa cgggtcctgt
     1621 cgcccgagag cagcccggac gacgcggcag tcgacgcggt ggacttgtta ctgcggtcgt
     1681 gggtcgcgtt gggtcgcgaa atagctgcgg agaaagggaa cgactgatgc ccgagcacgt
     1741 ctaccgggtg ctggtacgcg gacggtttga caaacttgac cccccggcgc gggagaagct
     1801 tcgccggaac gccgaccagc aggatgtgct caacgcgtcg ttcaccgaag aaggaacgct
     1861 cgtctacaac gagtccatcg tcgccttcac attccgcctg gtcgttcgag tcgagttcga
     1921 cgacaaggcg gagcagcggg cgcaggatgc cgccgaagaa cggctgatgg caaggttcga
     1981 cgagatcggc tgcggctatc gcgacctccg attcggagtg acggacatgg acagtatgaa
     2041 gatcaaccgg ccagcgcggg agcggcgctg aggcggaatt ccgcagaaca ggtagatcat
     2101 ggtcgatact gagcggacca cctggccgtc cgagccggta ctgcaggtgg cccagcccgc
     2161 acccgacccg aggcgttggt gggctctcgc ggtcctgctc gtcgccacgt tcatggacct
     2221 gcttgacaac aacatcgtca cggtggctat tccgaacatc cagcagcatc tcggggcgtc
     2281 gccaacgtcc atccagtgga tgaacgcggg ctatactctc gccttcgctg tgatgctgat
     2341 aaccggaggt cgactgggag atattttcgg tcgcaagcga atgttcttga ccggtgtcgc
     2401 cgggtttatg gcggcgtccg gaatgtgcgc gattgcgcag agtccggaat tcctcgtcgg
     2461 cgcccgggtg gtccaggggg gcgctgcggc cgtcatggtg ccgcaggtac tggcgatcat
     2521 ccacgtcagc tttgctcggg aagaagtcgg caaggtcgtc agcctatacg cgggcatcgt
     2581 gggcctggcg atcgtcgcgg gaccgctcgt cggtggtctt ctgctccagt ggaacccgtt
     2641 cggcctcgaa tggcgcagca tttttgcggt caacctcccc gtcggcgcgg tagcgttggt
     2701 ggcagtgtcg gcgtggatgc gggaatccag gtccccgaat gctcgccggc ccgacgggat
     2761 agggatgatc ctcgtcgccg tagggctgct gctcgtgctt tttccgcttg tgcaggggcg
     2821 cgagctgggc tggccgatgt ggagcattgt cgccatggta atcgctgtcc cagtgttcgc
     2881 gctgttccta cggtatgaac gggaaaaggt gcgccgtgac gattcgccac tgttggcgct
     2941 gaacctcttc aaaactggca gcttttctgt cggtgtcggc acgcaactgt tgttcagctg
     3001 cgtgccggct ggattcttca tcacctggac ggtttatctg cagggtggtc taggctggtc
     3061 ggcactgcat accggtctga ccacgattcc attctccgtc gctgttcccg tggctggcgg
     3121 actcgcggta cgctacattt ttccgaagta tggccgtcgc tgcctcatgg tgggagtggc
     3181 ggtgatgacg tcgggtgttc tttcctacgt gtggacggcg catcacttcg ccaccaccgt
     3241 gacagcatgg catgctgccc cgtctctgct gctgatcggt tcgggcatgg gcctgctggt
     3301 cgcgccactg accgggatga tcctgatcga tgtgccgccg cacgaagccg gcgcggcctc
     3361 cggaatcatc aacgcgaccg gccagcttgg cgcggcagtg ggcgtcgcgc tgatcggtgg
     3421 gctgttcttc tcccagggcc tcggcaagtt tgctggtaag cagactttcg gcgttgtgtg
     3481 gggcttccag tggggttgcg tagcgcgctt ctgacgcgag gccgggggcg tcatgggtgc
     3541 gggcacggct cctggagatc atggaggttc ctacaccgtc atgatcgtct cgaggtgcca
     3601 tgcccgccgc accagtatta ccgcctgccc ctgttctcga tcggctggct gccgtcggcg
     3661 ccggcaacca gcctccgtcg ccggcgggtc tgctggcggt cttcaaccag ctaccggacc
     3721 cccggaagcc ccgcggcagg cggcacagcc tggccgctgt gctgacgctg gcgacctgcg
     3781 cggtgctcgc cggggcgcgg tcgttcaccg cgatcggtga atggtccgcc gacgccggcc
     3841 aggcggtcgc gggcctgctc ggcgtctctc gagtgcccga ggagtcgacg tttcgccggg
     3901 tactcgccgc actcgacgcc gacgccctgg atacggcgct gggagcatgg gccgccgcgg
     3961 cgaccacccc gccggccggg acgcggcggc ggctcgcggt cgacggcaag acgctgcgcg
     4021 gctcccgcac gcctgacagt ccgggccgcc acctgctcgc cgcgctcgac cacaccagcg
     4081 gtgtcgtgct cggccaggtc gccgtcgacg cgaagtcgaa cgagatcccg gcgctgcccg
     4141 tcctgctcgc cgacctggac ctgaccgatg tgatcgtgac cgcggatgct ctacacaccc
     4201 agcgacagac cgcatcctgg ctggtcagcc ggcatgcgca ctacatcctg acggtgaagg
     4261 ccaaccagcc ggcgctatac gcccagctcg ccgccctgcc ctggcgccgg gtgaagaccg
     4321 ccgcgcgcac cgtcgaacgc ggccacggcc gccgcgagcg gcgcaccgtg aagaccaccg
     4381 aggtccgcgc gggactactc ttcccgcacg ccgtgcaggc agtgcaggtc acccgccgcc
     4441 gccagccgct cgccgacggg ccggccacga ccgagatcgt ctaccttgtc accagcctgc
     4501 cgacccacca ggccagcccc acgctgctgg ccacctacgc ccgcgagcac tggctcgtgg
     4561 agaaccggct gcactgggtc cgcgacgtca ccttcgggga ggacctcagc caggtccgga
     4621 ccggccacgc tccccaggtc atggccagcc tgcgcaacct ggcgatcgcg atccttcgcc
     4681 tgaccggcgc cacgaacatc gcccaggcaa tccgacacca cgcgcggcgc cccgaacgac
     4741 cactagagac gatcaagagc cttgcttgct aaccgacaac tttgccgggg ccctggttct
     4801 tctccgccct cgccaccggc gagccggccc ggaccgaccg ggtgacgtcg caggtccagc
     4861 aggccctggt cagccagggg cactcttccg gcgaggtgac tcggctgatg gccgagctgc
     4921 gtcggtgcga tatccaccag cctgacctca gtcttgtccc cgctgactgc ggcgggcggg
     4981 tgagcgtcac cgatcgtggg agtctgacga acgccttggc caaggtgcgc gcggaggaat
     5041 tcgtctccgg attcgtcaag accctgtggt ggatcgtggg tgcgctcgcc gtcgtgctct
     5101 gtctgctctt cctgctaccc gcccggcgcg gcgggccctg agagcggacg atcgggcgtg
     5161 ttggccaggc gggccgcgga ttcgccgacc cggcgaatcc gcggcccgcc cgagagcccc
     5221 cgggcacaga ccagttccat cggcctccga accagagcac cgccggctgt ccgtggcagg
     5281 tgcggtcgat ccgcggtcag agcccgttca ccggaccacg cggtccatca gccggtccag
     5341 ctctacctcc ggtttggcag tgataccgcc atgcacggcg ccgggctgaa cgactgtgct
     5401 gcgcggcgcg gtgagccagc cgaagcgtgc ccgcgccgat ctcgtggcgg ccgggccggc
     5461 ggcgggatca ccggcacaca ccatctggat aaaattcagc gctgcctgga tcagctccac
     5521 gtcggcattg gagtccagcg ctctgagtcg ttcggtatca acgttgatcg ccgcggccaa
     5581 aaattccgcg gcaggactgt agagcagtac accgacgttt atccgctcgc cccggtcgac
     5641 ccttgggaca gcgaacagaa gagcatagtg agcctttccc tgcaacgttt ggtgacgctc
     5701 cgtgagcgtc gctgggtgtg agcgtccctg ggggtggaga cgatgaaggc gcggggctcc
     5761 ggtaggaagt tgttccgacc aaagagcaac tccgaaggaa ccccacgcct cgatgagttt
     5821 cacatacacc gccgagctgc cgttcggcga tcacaccgtt ttccgtctgg cgggtcttct
     5881 cgtggcggag cgtcaacgtc gtggtacccg caagggcacc cggacgctgt ccgcgttgga
     5941 acaggccgtg atggtcctgc gctggttctg tgacggcacc agggccaggc ggctcttctc
     6001 cgatcatggg gtgtcccggt cggtgggcta ccgctacctg cacgagggag tcgccgtgct
     6061 cgcctggcag gccccggacc tgcgtgaagc gctgatgcgg gccagggtcg ccggctacga
     6121 gcatctcatc gttgacggca cggtcatcga gaccgaccgg ctacgcatgc ccggcccgac
     6181 cgaaggcgtg gacctgtggt ggtccggcac gatctccaac cacggtggca acatccaggt
     6241 gctctccgcc ccggacgacg gctggccact gtgggtctcc gacgtgcggc ccggccgcga
     6301 gcacgactcg accgccctga aagcctccgg ggcgctgccg gttctcgccg agtggaccgc
     6361 cgacctgcac gaggtgctgt tcgacctcgg ctacgaaggg ctgggcaacc cggccgggcc
     6421 gctcgcgacc gcgtacaaga agcccaaggg cggcaccctc accgacgaac agaaagcgca
     6481 caaccggatc cacaacgcgc tacgcgccgt cggtgaacgc gcgaacgccc tgctcaaagg
     6541 caccttccga ctcctccaca acatcacgat cgacccctgg aagatcggac ttgtcgtgaa
     6601 agccgccctc gtcatcctcc acaccgagca ccgcagaacc gcctgacacc caacacacca
     6661 acacaccatt gcgatcacgt cacgtgacga atcgttaccg ggaaaggctc agtgatgcga
     6721 gccatcagcg cggcgctgtc gaccggcatc tcgctggtct cggatccgga tgacatggat
     6781 gcgccttcga gcgagaactc ctggactccg ggttccgatc ggatgagaag gtcgtcgccg
     6841 gtcccgagcg acgtgacggt gggccccgga agccagagct gccatccgtg gggcggcctg
     6901 ggccaagatg ggtctggaac ccaacctggt gggggagtcc agccttcggg gggtgtgggc
     6961 cagcctggcg gtgggttgaa ccgcatggtc actgcccacg ctgcctgatg ccgcgggagg
     7021 cgtcggcggg cttgagagtg aacggcgaag gggacagcgc cgcgccgagg tactcgaggg
     7081 tcttctgagg gacgatctcg tcctggtcga gccggaactt gcggaacgtt gcgcggtctg
     7141 cagcgacgat cgcgagcggg atggtctccg gaagcccggt cgcaggcgag atccggtcga
     7201 ccccgaccgt cagggcaatc gagtggatct ttccttggcg gtcggcgccg aagacgtcgt
     7261 gcagcgtgcg tacggcggtc tggaagacgg cgctcgcgta gcggtccttc tggaccgtcg
     7321 ccggcagctt ggtcgacgag atctcgtcct tcctcggggc gtacttgtac tccttgaccg
     7381 aggggactgc ggatggttca gggacagcgg ctgccagacg cagctccctg ctggagagat
     7441 cgaactcgta gtcgtgagtg actggaaatg catccgggta ggcggagttc gacaggacga
     7501 tcccgacgta ctcgcggatc gccgcctcga cgtcgaaggc gagatcattg atcagtctgg
     7561 tgagtccccg gttccgctcg tcggcgtcgg cgtctctccg acgacacgct tcgacgtgga
     7621 ccgcccgcgc cgcggcgagc ttcgccaggc gagcgtcctc ggcacgctgc cgctgctcca
     7681 gagcggagac atgcgccgtc cgtatcgctg acacctgttc ccgccaccgc cgcagcgcct
     7741 gctcgtgcgt ggtctgagct tgagcgatcg cctgggcatg ttttttcttc gccccgaata
     7801 ggactcccgg tacttgcggc tcctggtaga cgggttccgc cgggtacaca ggagcagcaa
     7861 cgggcggtgt cgggactgcg agagcaccgg gctcgaacgg tggatgcacg acggtcgtga
     7921 ctttcaaggc ctcgagatca acatagctgt cgaccaggag cgccgtggcc agaatgccgt
     7981 cgatctcttc gaatgtgctc gcgagatcgg cattcagcga cccgacctcg ctcaatcgcg
     8041 ccgcgacgta cagcaggccc gcttccttca gcaagcgggc ctgttctttc gtggacgcct
     8101 tggccgccgc ggcggctgcg cgctcagcgg cccgagcctt ctgcgcggct tccttttcag
     8161 cggcaaggag tgcacggtgg gccgcagccc tctgctgccg ctgccgcttc tcggcctgcg
     8221 ctgcctggta ctgcaactcg gcgaatagcc cccgccgcgt ggccaccggc accccctccg
     8281 aaccaggaac aaccttgcgc tcagctaccg tatcctcacg tcccgacgat ttctcgcggt
     8341 cacgacagat cgagactggt tatcccgcga ggctccggtg gacgccgccg ccccttccgg
     8401 ccccggaccg ccgcgtctcc agcacgcgtt ggaatccgga cagttcagcg ggtcaaccgt
     8461 cttcgtagcg gccggcatct ggacagtgct ggcgcgctga cccttgagca cggcgggccc
     8521 gtcagtgtcc ttgaagacgg gagggcatcg acgggtgctg acaaggaagc ctgcccagat
     8581 ggtcgttgat caggcagcat gcgaaccatc gacggcggac cggccctccg ggtgacgccc
     8641 ctactcggtg atcttcctgg cctccgagtg gaacattcga acttcgcggg ctcggcggac
     8701 aggttgagct cgccggaccg ggcaagcttg ggacgacgag ccatcgtggg ttgcggaggc
     8761 tgtccggagc gcagccacgg ggcagataga ccagggccgt agagatctga cggtgatctg
     8821 acagatgttg catacacaac aacagtcaga tcgccgtcag gtcattttcg gccctgtgag
     8881 accctccgtt gaattggctt gcagtctccg ccgggtgtgg ggcagctgca cgtccgggcg
     8941 cagcggcgat gagagcgttc gtgggcctgt tctggccagt cccggggtcc agcgccgtct
     9001 accaccgcgc acaggcgtag gggcaggtgc ctttgcccca acgcatgccc ggagcgctgc
     9061 ccagcggagc tgtttccgag cgtggccgtc tgcgcgggtc atgtctgtcc tggcctcgtg
     9121 gctgcgcctt cttgctggcg gggtatgccg cggcgaagaa gatgtgtggc gcgtatgcgc
     9181 aataaccccg catgatcgat atcgaggccg gtcccggagt ggacggtgtc gagtagctcg
     9241 gcgatgacgg ccagttcggc gtaccggccg ctctctgtgg agagtgcgtc tgcgaaacgc
     9301 gcctgaacct gtgcggcgag cgttggcatg aacaggctgt ggcagtagag ggtggcggcg
     9361 tcatagccgg cgggtgccag gccccagcct tcccagtcga gcatgcagag ggtggggccg
     9421 cagaggttgg cccagtgcag gtctccgtgc gcggttaccc acggtgcggg cgaggtggtg
     9481 gtgatcggtt cgccgagaat ccttggcatg acgtcgtcga ggtaggactg ctcgatggtg
     9541 cgccggtcgg tggagaccgt ggcgaggatg cggaaggaac ggcgcagtgc ctggaaccat
     9601 tgccctttcg gtgagtcggt gagccgccgc ggcacggtcg tgacggcgag aggtcggacg
     9661 tggacgcggt cgtatagctc ggcgcggtag tcccagccgt cgtggtgatg gtcgtggatc
     9721 gcgcgtagcg ctgggcgtgg gatggatgct ggcagcgcct gctgtgcggt gcgtccgccg
     9781 tcccagaacg tggtgatctg ctgtccggct tcggtggcgg cgatccgtag ccagcctggg
     9841 ctgtcggggg tcattaccgg tcggccgagg gttcgtccgg cgaagcccca cgcttcctca
     9901 gcctgggtcc ggtcgaccgt gacccggagg gcggcgctgg cgcgctcgtg cgctgcgcgc
     9961 atgcgggtga cggtgtctgc gtcgttcggc ggcggccaca tcagcgtgcc tgcggcgtta
    10021 gcgcttcggg gagtgcggga gcgcggagga ttgtctcgcg cgctgtggcg gcgagtacgc
    10081 cctgggtctc ggcattcagg ccgaggcggt tccagtggaa gatcacatgg tggccgagga
    10141 cgtcgcgtag cccgcggcgc agggtcccgg cgtatgcggc ctggccaagg gcccgaccgg
    10201 cattgtgaaa ggcgctggcc cagattccca ggttggccag cggtcggtcc gcgccgaaca
    10261 ggtcgcctgc cgggtcggtg tcggtggtca gcagcctgcg tagagcggtg gccagccgtt
    10321 gaatttcagc agcggtgggt gatgttgctg gtggagggcg taggcggctg acacggttga
    10381 agacgtcgcc gcgttcgtac cagtccaggc ccgcggtgcg cagcagcgtg ccgatcaaca
    10441 gcatcgacag ttcgcggcgg ccgagagtcg gcggggtcct gctggtgatc tcgctgtgga
    10501 tgcggtcgag gacgtgcccg ctgtcagcgg tgaacagccg gtgcgcgacg tcggtgccga
    10561 cctcgccgcc gagggcgtac tcctccggct cgtagatccc ttccgcccag gtggggatcg
    10621 ttccggccgc ggtcaggtcg tcgaaggcgg agcggagggt ggcacgaaga tccgccacag
    10681 attggccact ggctggagag agccgtagcc gccagtcggg cgacttgcgc acgaaccacc
    10741 aggaggcgac agcgccggcg gcttgggcgt ggcgtaggac aggtgccagg tgggtggctg
    10801 cgacggtctc tgcgtccgct ggctcgggaa acgtgacacg cacctggaac caggcagcac
    10861 cttggactgc gagcgcggcg cgacctgccg cctggtaggt ggcgacagct gcggcgagct
    10921 ggtcgggagg caaggcggca tgggctgccg cagtgggtag cgggatgccg gccagcaccg
    10981 cgagtacggc ctgttcggtg ccgatgtctc ggctggggac ggtcagtgga tcagcaggca
    11041 tctgtcccat ccggtggccg gtgcgccggt ggcgacgctg tggaggacga gggcgatgcc
    11101 ggcgtctcct tcgaggagcc catcagcccg cccgctgctc gaaagggcgc agagcaggag
    11161 ggaagcggcg agtgtcggca ggtggcggct gagggtctcg gtggtggcgt cggcggcggc
    11221 gcgggcgacg gtttggtaga ggcctgccca tccgtggcac agtccggctt cggtgaggtg
    11281 ggcgagttgg gtggagtcgg tgaggcaggc tgcgagtgcc tgttcggcgg cgttctggcg
    11341 ggtggtgtca ccggtggcga tgccggcgag ttggagggcg cgggcgattc cgggggtgcc
    11401 atagcaccag ctcggacggg cggggccggg ctgggccggt ctcgcggcct gctgatcggc
    11461 acgggtgatc cactgtggcc aggacggacc gctgggggag tcgtggcgcc attggtcata
    11521 gaaggcgcac agcgcgttga tggcgttggt ctggccgtgg acgcgtatcc cggcgcgtgt
    11581 ggcgagcgag agcagggcca gtgggccggc ggcgccgtgg gccatgccga ggttggcgtg
    11641 tccaccggcg aattcggcag tgttgccctg ggacgggtcg tggctgcacc accagccggg
    11701 gagttcctct ccgtcgaggt tgagaggtgt ggtgaggcgg acgaggtagg tgaggatgcg
    11761 gccgagggcg tcgtcgccgg gggtgtgggc gaggaggtgg gcgccaatgc cggtgagccc
    11821 gctgatgacg tcgtactcgg tgaaccgtcc cggttccccc tggtcgatgc gggcgttggc
    11881 ggcgtcgacg aggcggtggg cgatggtggc gacggcctga tcgagcgcgg tgcgggcggc
    11941 ggtgtagcgg cgggtctgcc cggctgcgat gtgaacggcg aaggcgaccg ccggggcgcc
    12001 ggcgtagagc gagctgttca tcgccacgct gaggtggccg gagatggctg cggtcagcca
    12061 cgcctggacg ggctcccagc gctcggcgct ggcgtgcgct cgctcggcgt gcaggagggc
    12121 gatgccggcc gctccgtcgg cgagcgactg cgcagtctgc ccgagttctc tgggggatgg
    12181 gacggtgagg cgggtggcaa ggcttgctgc ggtggcggcg gcctgatcgc aggcgatcat
    12241 gagacggtcg cttccgtggt cgcgagggcg cgtgcggctg tggctcgggc gagggcgatg
    12301 caggtctgtt cggcggcggg gttcaggccg agggttcgga cgacgtgcag gtgcagcagc
    12361 gaggccaagg cctggtcagg cgggcgctgc gcggcgaggg cgtcgcggta ggcggccagt
    12421 gctgtggccc gcggctgcca ggcggacagc acggcgtccg ccccgggaac ggcccgcaga
    12481 tgagcgaagc tatctgcggg gttggccagg tgcaacgtgg tggtgcgttc cgcccgtggg
    12541 acgcgggcag gctcgtgggg cagcacgtca cgaagccacc gcatgccggt ggacaacgcg
    12601 ccggtgaagg cgatggccat atcgaccagg ccggcgacgg tgagcgctcc gacggacagg
    12661 cgggcgctgg cggcgagacg gcgggcggcg agggcagcgg cggagtcggc ggagaagacg
    12721 ccttcggcgg cggtcatcgc cgggccatag ccgtagcggc cggtctccgg ttggtaggtg
    12781 tcgaggtgaa ggtgcgacag cagtccggcc tcgcgctgta ccgcagccca ggttcccagc
    12841 cgcgtggccg ccagcccgta gccgccaggt tcgttgacgg cgaggcgtag ccgcaggtgg
    12901 ggctcggtgt cccggtacgg caggaaccac cacgcgggcg ggtcgggcca cgcgtccaag
    12961 aggtcgtgga ggcgggcgag gagatcggtg gcccggtcgg ggtggccgta gagccgggcc
    13021 gacagccacg gcgacacacc gggtagctgg gcatccgacc gagcagcggg cacggttgcc
    13081 gcgaggcgct ccggtgccgg ccccggcagg ggtgcggcgg tggtggccag cgggatgacc
    13141 agttcgtggg cgtggccggc gagccagccg aaggcttctg gagcggcgtc ctcgtcgagc
    13201 cgggcggagc cgtgccggtg caggtgatcg cgtagcaggg cgagatgggc gtcgacgtgc
    13261 agatcgaggc gcaatcggtt gtcggtctcg acgagctgga cccgcgtggg cactgggatc
    13321 gtgccgcccc agcgggccag cgcctcgcgc cattcctgcg ccgactcggc gcggctgggc
    13381 aggtcggcag ctgtgagatt ccagtgggcc ggggcgagca cggtgcgccg atggacgagt
    13441 cggggaagga acggcagccc accggcagcg ccccaggaga aggggatgga gacggcgacg
    13501 cgggcggtgg gtagctcgca caggaaccgt gtcagcgggt gggtgtggta ctggaactcc
    13561 actgcgtgcg cggcggacgg ctcgacgaga cgccggtcgg gcagcgacac cagatacagc
    13621 ccctcagcgt cggcaccgac agccagatcg gctggacgca gcacgcacgg accggcgtcg
    13681 tgatgctcgg caagcgtgat caccgtgtcg gtgagccgcg gtgatcgggc cacgccgacg
    13741 gtggctgcgg gaagcggcgg acaggacacc tgcgcggctg tcgcgccggc ccgcatggtg
    13801 ggtagggcgg cgtagatgtc gcggaaccgg tcgaaggacg cggggtcgag caggtgcagg
    13861 aagcggccag tggtggttgc ggcggcgcgt ccgcctccgg tcacacgcag ggtgaacagg
    13921 ccgcgggaca aggccggcag gtcgttggcg tggacctcgg cgatgagttc ggcgtgcggt
    13981 ggaacccggt ccggtgcggt gtcgccggcc agagccgcga tggcggcgtc gccgaggcgt
    14041 gcctcgagcg cgccgtccag ggccgcccgc tgcgtgaggg cggccaggcg ctgatcgcgg
    14101 gccgcgttcc cgcgggggcg gtgggagcgt gtggagccgc ggaaggtggc gggcagaccg
    14161 aggccggtgt cagggttgac ggcttccagc agtgggacga gggcggcggg accgtagcgt
    14221 tccaggaagg cttcgtgcca gtccgcccac tccgggggaa cggcggtcgg ccctgtgagc
    14281 cgggcgagcg cccgagcggc ggccccagcc tcctcggcga cagccgccgg caggaccacg
    14341 tccgcgttca acacgaggcc tacgtcgagg tccgggtcag cgctgggaac aacgcgccgt
    14401 tgaagcgtct ctgcctgcgt gcgcagcgtg cgacggtgcg aggcggagcg cgtgttgtcg
    14461 tggtgggcga gcaggtcttg taggtcgcgg atcacgttga gacggccggc gagtgggggc
    14521 aggtcgtcaa tccgggctgc ggccagctgg tcggcgactt cactgagtgg atcggtgatg
    14581 gttgtcgccg ggcgtagggg cgtgtgcagg aaccggcggc ggaccaactc gatcaccata
    14641 gtctcgatct ggccggcggc gggagcgggt ttgtcggcgg cgaggcgagc gaccagctcg
    14701 gggacgggca gcgagctgac cgcgtggagc aacgccgcct ccacagcccg ggtgcggcgc
    14761 accgacacct cgaccaccga ctccggcccg gcgtcgtcgc cggaccgggc gacagggccg
    14821 atgaacagtc ggtcgcctcg ggcgactggt attccgtcgg cggtgaccgg cagccgtcgc
    14881 agcagcgtgt cgaacgcttc caggtcgtcg gcgagcgcgg cgagccaggc gccgcccggc
    14941 cgggcgtgaa cccgatggtc gtcgccgagc cggacgcggg cccgcgggcc gaaatccgcg
    15001 ggcccgacac cggcgaacag gccgaatgga gtggcgcgcc cggtcatccg cagtacgtag
    15061 cgggctgtcg cagtgacagc ccgccgggcg gtccgccgat cgtggcactg cccgtcgaag
    15121 accgacgcga cccgcgcggc cagcgacggg ctggcgagcc tcatcgcgtc ggcgaacacg
    15181 ggccgtgccc agatgtcccg cagccaatcc gtccagccgg ctacggcgcc gtcggtggtg
    15241 tcgtcgaggt ctggccatgg gggcaggtcg acatcggtgg ggaccacggc catccgtagc
    15301 agcggaacgt caaggctgcg gtacatcacg cacctctcag cggcggaggt tcagttctgc
    15361 ttgcagctgg tgcaggccga cgagcaggtc ttgccgcagt tgtcgctggt ggagcgcagc
    15421 agctcgggga tgacgggtcc gccgtcgacg atctcgacgt ctaggtcgta gtcgccggcg
    15481 agggggagcg gggccggggc ggttgtgtgg gcaggagtca tggcgatgcc tttccttcgg
    15541 aaggggtggt gaacgcgtcg ctgtgttggt caggaccagc tcaggacgac gatgcggtgg
    15601 cgcttggcga tcacccggcc gggcggaagt gcctctgccg gagttgtggc cggccagacg
    15661 ctgatcgtgg ccggcgacgc gtcgcggtgg gttcggttcc aggcctggac ctgcgtgacg
    15721 accaggccgg cgaggcgggc ggcgtcgggc ccgtgggcgt aggcgccgaa ctcgtaggtg
    15781 tcgtcgccgt cctcgacctt tcgcagggtg aggtaggcga agctgtccgc ttccacggcg
    15841 gtgggcgtgc cgatcgggga gacggggtcg acgagctctc gagcggtcgg ggaacgggcg
    15901 cgggagagca agccgtagtc gtcgaggctg ctggcaagcc acagcagcag cccgtcgaac
    15961 ggttccatcc cgccgaaccg cactcccgac cacgcctcga cccgcggggc gagtagcgcg
    16021 gcccgcagtg cggcggcgtc gagttcggga gcctgctcgt cgaaccgcag gcccacgtcg
    16081 gcatcgtgaa gctggacgag gcgttcggga tgggcgccgt cgccgcgcac gggcacgaag
    16141 ccggccatct gatggtcgag actgaccaga acgccgtcgc ggggggtgag cgcgaccgtc
    16201 cggctcagcc cccgcatccg caggggaacg acgatccggc cgtctggggc gagctgatcg
    16261 gtccaggcgg gtgggatgtc ccaggcgccc gcggtgacga tgatccggtc gtagggcgcg
    16321 tgctcgggga cgccgtgctc ggcgtcggcc agcacgacgt ggacctggtc gtagcctgcc
    16381 gctgcgaggc agtggtgggc tcgttcggtg acgtcggcgt cgatgtccat ggtcgtcacc
    16441 gcaccggtcg ggccgacgag ttccgcgatc agggcggcgt tgtagccccc ggagccgact
    16501 tcgaggaccc gcatgccggg gctgatcccg gcctgttcga gcatcgtggc ctgcagccag
    16561 ggagcggaga ccgagctgac ggtgatgccg tgctggtcct gcttggtccg cacgatgtcg
    16621 tcggcgtagg cgtcctggag cgacacctcg ggagcgaaca ggtgccgcgg caccgcgcgg
    16681 aacgcggcct cgacctcctt cgttttgatc gaacccgccg cgacgaggtc atccacgagg
    16741 cgggcccgca gatcctcagg cgcgtgcttc cccgtcggct ccgggcggtc gatgatgccc
    16801 gtgcgcgtcg ctcaacaccg ttctcctctc gcgatcgtcg gatggtgggg tctcagcccc
    16861 aggtgatcag gagctgggct gatggtttcg tgaggagccg tccggccggc gccgaggcgc
    16921 ggccggcatc ggtggggtag acgcggatgg tggggtccgg gccaccgcgc cgctcggcgt
    16981 cccacacgcg gacgtcgtgg gtgagcaggt ccgcgagccg gtaccggtcg gggccgtacg
    17041 cgacaacccc gatctccacg ccggtcccgc ccgtcggggt gaaggccagg aaggcgaggc
    17101 tgtcgtccga ccagcaggca gacaccccgg ccgacgcatc cgcaggcagt tcggctcctg
    17161 cggatgcgtc ggtgccgtgg agccggccgt aggtgggctg cacggtggcc agccacaggt
    17221 ccaggctcgg caggtcatct gcggagccgg tcgtaggggg cgcggagcgg gaacccgaag
    17281 tacccgtcgt tgatcagtgc cgtgacgtcg gtgtagccgg ctttgtccag gcaggcgtgg
    17341 gtgcggtgga ctacggactg gtcgatgtcg atggtggtga cgtggccggt tggcccagtc
    17401 agctcagcca gcagcgccgc ggtgtagcca ccggaaccga tctccaggat ccgctggccg
    17461 ggttcgaccc ggagctgctc gagcgtcgcc gcgacggtgg agggccgcga caccgcgctg
    17521 agcggtgccc cgtagacatc ccatttcgtg acgacggcgt cgtccttgta ggcctcctcg
    17581 gtgccggcgt cgggcaggaa caggtcccgg ggcacggccc tcaacgcggc tacgaccggg
    17641 gcggagacgg gctccttcgc caggacaagg tcgaccatgg ccgtgtgcag cagcgcgatc
    17701 gacgcctgcg tggaagcagg catcacgcca cctcgccgag caggtcgtcg tactcgcccc
    17761 gcttgaccgc acggacgaag tccccgaacg cgccgggggt ggtccgcacc gacgggccca
    17821 gactcgacct gatcaacaca cggtgcccgt cgagggcgac ttcgacggca tcgggcaccg
    17881 tcgggtcgag cgtggacggg cgccgccatc gtgggacggc cgggacaggc atgccggtgg
    17941 gcgcaacaga cacgggttcc tcgaaacgat gcgatcggtg tggacgggtg gagcccgccg
    18001 aacccgggcc gcacgactcg gcccaggccc ggcgggagca gaagcggcga cacgacacga
    18061 cccggggttc atccgccctg agctggtgga acggacggga ccggatcggc gtgttcaccg
    18121 cgcgcagcac ccatgacaca ctgcgcccaa acggagcaac agaacgcaac ggctcgttgc
    18181 gtgcatgcaa cagctcgttg cacccacctg cgaaggcgtc gacggggagg ccgaaggtgc
    18241 aagctggtca gcgaaacgac gcactcgcca acctggccga tctgctgcgg acactgcgtg
    18301 atcagcatcg gaccaacaac agccggctcg aagcccgcac cggcttcaaa cgccagcaga
    18361 tctctcgggc cgtcaacggc caggagatcc cgtccgcgga cctcgcggac gcgctggaca
    18421 cggcgttggc cgcagcggga gccatccggc gattgcggga cgaagctgtc agggagaagc
    18481 gggcccggga cctggggctc gacccgagca ggcaggagga acccgtggac gccaaccgtc
    18541 ggcaggcgtt cgaactcgcc gccgcgagcc tcgtcgccgc ccagatgtac cgggagtgga
    18601 cctcgtccgc ccccgatgtg ctgaccctcg acgagatcga cgacgcgatc aacgcgcaca
    18661 ccgtcgcgtt caccgtcgaa ccgcaccagc ggctcgcgcc gaaggtgtgg aagacgtgga
    18721 agtcggcgca ccaccacctg atgaacggca gtggccgggc ccgcccgcag accaggctca
    18781 ccgtcgccgc cggctacgcc tcctacatgc tgtcgcggct gtcgttcaac ctcggagaca
    18841 ccctggcttc gcgccggttc atccgcctcg ccgaagacca cgcgagccag accgacgacg
    18901 tggtgctgac cgcgtcggtc ggggagatgg tgacgacgct ggcgttctac ggccgccgct
    18961 accaggaagc cgccgtctcg gctcggaaga ccgcggtcgt ggcggacaac ccgtacaccc
    19021 gggcccggat cgccagctac gaggcgcggg cccttggcgc gctcggcgac gtcgagggca
    19081 cccgggcggc gttgaaccgg atgcgcacgt cggtcacgga cctgccgctg cagcccggga
    19141 tcagcccgtt cggcccggcc gccgccgaga tgatgtacgc cggggtcctg acccggatcg
    19201 gcggtggcgt cgaggccgag ccgatagccc gagccgcgct cgccgcctac gaaggaggcc
    19261 aggcgggcgg gttcgaggac tacggccacg cgctgctcgc gctcgcggcc agcctcaccg
    19321 cccgcgaaca gcccgagatc gacgaagccg cgaccatggc cgggaaggtc gtcgacatgc
    19381 tcgacacccg gcccaccgcc tcggtctccg accgggtcgc agagatcgcc atagcgttca
    19441 ccggccaccc caccgtcgaa cccgtccgtg acttctggga ccgctggcag gcacgccccc
    19501 gcctcgaact gaccacgggc caggcgtgac catgaccctc cactacggaa ccccgaccgt
    19561 cgtcaccatc cccaccgtgc tcaccgaacg gctggtgctg cgcggctgga aggtcgtcga
    19621 cctcgacccg tacgcggcga tgaacgcgga cccggagacg atgcgctacc tggacggcac
    19681 gttcgaccgg gccggcaccg agcggctggt cacccatctg atcggcatgt gggcgatccg
    19741 cgggcacggc atgtgggcgg tcgaggaccg ggccagcggg gagttcctcg gccgcgccgg
    19801 cacctacttc gcccagggct ggccaggcgt ggaggtcgcg gtgtcgatcc gccgcgaccg
    19861 ctggggccaa ggcctgggca ccgaagcgat cacggcggcg ctcgacttcg ggttcgccca
    19921 cctcgacgtc gacgagctga tcaccgcaac gcatcaggag aacgcgggca tgaacatgat
    19981 tgcccgcaag ctcgggatga ccttccgtga gatcgccgac gtcggcccgt ggaaggcgaa
    20041 caacgtccac gcgatcagcc gtgcctcctg ggccgccaac cgacccgagg agagcaaagg
    20101 ctgacttgcc cgcggaacag cttcgttgat ctctgcgtca gagcgtcgct gctgtcatgg
    20161 cggtcgcgcc tggcagggac agcgcagcgg tcccggccga tgcggtgcgc ggtgatgttc
    20221 atttccgtga gcgaaactac gtcttcatcc tgataagtcg caaaggccgg ataggtcggt
    20281 tatgcccgcc ggagggggtt gcgggcccgc gacctgcgag aacagcgtcg ccgaacgtct
    20341 cgtccctggc tttgaaggcc tgttccggga cgaattgcgg gggcgtgggc gggcttgtcc
    20401 cggacggcgg catggagcta cggtcgtatc cgcccccttg accgccggac accgacccgc
    20461 tagcgggcgg ccggttcggt gggagacggg gtggtggtag cagcgaggcg ctgggacgcg
    20521 tttccggtcc acaggactgg tgacggagcg agagggtgtc gctgtgagtc gggtggcttg
    20581 cgagccgcgc ccgggagatg gtgtcaacgt ccgcggtcgt tgctacagcg gtagctacac
    20641 ctggcgggac tcccgaccgt ccgattacaa gatcggtacc atccgtccgt gcgcgttcgc
    20701 gaaagcctat acaggctgct tgacgacctg gccacctcgg cctccatccg ctgacgtccg
    20761 tcgttgttcg ctggcccggc tgtgtagatg cccataccgc cgccacttct caggagtggg
    20821 ctgcgctccg ctgtctccac gagtgcagtg gcgttcacgt tcgcttgtgc ccgcaacgtc
    20881 agtccccaac tcccggcctg ggaacggacg cgggccatgc cgagacggtc gccaccccgc
    20941 gcgtacaggg gaagtcgcgc gacgttctaa gatcgtgtta tgcgagtatc ggggaggggt
    21001 gcgccgggtg acgagccctg acgtcggtgt gccgacatac gatcagctgc tctggccgac
    21061 gatcaacgca ctgcgcgatc ttggagggtc cggcgcgatc tcggagatta atgaacgagt
    21121 catcgagctg gagaagttta gcccagagca gcaagatcag ctacatggag acgggccgcg
    21181 gacggagatc gagtatcggt tggcctgggc tcgtacctat ctgaagatga tgggcttgac
    21241 cgacaatagc agtcgtggcg tttggacgtt gtcggaacca gggcgctccg ttgacagggc
    21301 agatattccc aagatccatg ctgaagccaa gcgtgcttgg gccgctgaac gtgccgagaa
    21361 ggcgcgcaag ccggccgatt cagaacccaa ggccacctac gaacaggcga cgtcggacga
    21421 cggagaaaaa gaccaggaaa tcgcctggaa agaggaattg ctcgaagcgg tgatggcgat
    21481 gccgcccgac gcattcgagc gccttgctcg ccggctcctc cgggaggccg ggtttatcag
    21541 cgtcaatgtc accggcggca ccggcgatgg tggcatcgat gggctgggaa tctaccgtct
    21601 ctcgctcgtc agcttcccgg tattcttcca atgtaagcgg tacaagggaa gtgtttctcc
    21661 gagcgctgtc cgagatttcc ggggggcgat ggcgggcagg ggagataaag ggcttctgat
    21721 cacgacggga tcgttcacct ctgccgctca aaaggaggca acccgcgacg gcgctcctcc
    21781 ggttgatctg atcgacgggg atagactctg tgacctcctt cgtgaataca accttggagt
    21841 caaggtggag atcgtccagc acgaaaaggc catagttaac cgaagattct ttgacgacat
    21901 ttgaattgaa ctcgcagaaa gccggcagtc tgcgctaaca tccggctcgt ccgtcggctc
    21961 tggatggcga agtgagtaac ccgcggataa gagatcttcg gtggttcgtc tgccggtgtc
    22021 cgtggtcgtc cgccggtgcc ggtcacaggc tcggtctcgt ccgccgagtc cgtgaccgtc
    22081 cgccggtgcc ggtcacaggc tcggtctcgt ccgccgagtc cgtgaccgtc cgctggtgtt
    22141 cgcgggcttg gctgccactc tggctgccgt ccactgcggc ctgctccctg acggatggag
    22201 gaagtgcgcc caaaagagcg cggccatctc ggcagcatcg actacggcag cagcatctcc
    22261 tcctgggggt cgtagcagac cagacgcatt gatgccgcga gttcggctgt gtaggcggac
    22321 acctcctcgg ccatgctcca cacgacgcag aggtagagga atggcccgga cggctggggt
    22381 gtgaccgacc acggggcggt gtcgtcatcc ggccaccggt gcgtcaaagc ctcacagtag
    22441 gcggcgatga ggtccgtggc gggcgtctcc gggtcgtcgt cgtagcgctg gaacatctcg
    22501 ttgaacgcgg accctgcggc cagattgtct gctggtcgct cgccttccca gctcacaaga
    22561 tcgaaactca cgggagcagt ctgccatctg ggtacgacat gtcaggccaa gggcggtgcc
    22621 gccctctgta ggcgtctaac ggcgtggtgc gatcggaagc aacctggtcg aagccaaaac
    22681 gatctcgaat ggtgaccgca gacaggctcg tcgctggcag gccgggcggg tcgggctgtc
    22741 ggaggagcga agcgccctgg cactggtgat ggggctgtcg gctggcgtgc cctctgctcg
    22801 ttttttgcgg ctgcccaccg gcgtgcgcga cgaacgtccg cagaaccgcg ttccgtgccc
    22861 cggctggttc accccacgct gacgaccggc gcccttcgtc gaacgcctcg gatggtctac
    22921 gcggtgcggg gtgcgacggg cccggcgagc acggccgcca ggccgcgcgc aggcggtcgc
    22981 gcggcgcggc ccgcaccgcg acttgatcct aactcgggta attcggcagt ctcgggctct
    23041 cgctgacggg ctggtggtgc tcgccgtacc gtgatcgggt ggaggtagcg gttgctgagc
    23101 ggttggcgag cgagctgctg accccgttgg gggatcggtg gcggcatgtg caggccgtgg
    23161 cggcggctgc ttgggaggtg tccgcggccg tcgatccgga ggagcgtgac ctgctcgtcg
    23221 cggcggcctg gctgcatgac atcgggtacg ccccgccgat cggtcaccta cggttccacc
    23281 ccgtggacgg cgcccggttc ctcgaatccc acgatgcgcc gaagcggctg tgcgcgctgg
    23341 tcgcgcatca ctcgtgtgcc cggtatgaag ccgaggagcg ggggctgacg gcggagctct
    23401 ccgcgtggga gctggaggtg tcgccggtga tggacgcgct gtgcgccgcg gatatgacga
    23461 cggggccaca gggccagcgg ttcaccttcg acgaacggat cgcggagatc ctgtcccgct
    23521 acggcgacgg ctcgatcgtc caccggtcgg tcacccgggc tcgggcggac ctgcaagcca
    23581 ccgtggaacg cacgaccgca cggctcgtgg cggttcagcc gaggtagggc gtggcccggt
    23641 tctccaggta gtgatcgatg cggaggcgca tcgatgggtg gatgttcagc ccgtccaggt
    23701 cctcgggcgc gacgaacttg acctccttcg tctcgctcga ggtgcgtagc tctccgccaa
    23761 gattgcgggt ggtgaagcag agcgagaact gctggcggac ctcgccgtcg tcgtaggcca
    23821 ggacatgccg ggggttggtg tagaccccga tgagtccggt cacctcgatg tcgatgccgg
    23881 tctcttcctt ggtctcgcgg acggcggcgt cggtgatgga ctcgccgagg tccatgccgc
    23941 cgccgggcag ggcccacagg ttgttgtcgg tcttgtggac catgaggatc cgcccggcct
    24001 cgtcggtgac cacggcggtg acggacggga cgacgctgtt cgccttgggg gcgttcgggt
    24061 cgttgaagta gtcgatccgt gccaagaggg tcaggctcct tcggtggtgg cccagatgcg
    24121 ttcgaagctg gcggcgtagt ggtcgaagag tccgccgggc tgggcgcgta ggtgcatgac
    24181 gggggagtgc gcggcggggg cgccgtagac gtgggtgttc accagcatgt cgccgtcgaa
    24241 acggtagatg gagttgtaga gcgtggtggc gtgtagccgc agctcgattc cgggcgcgtc
    24301 gcgcaacgat gccaggtagg tgagggtgat ccgggttcgg gcggcgagtc cgtcaccgat
    24361 gccctcctcg tcgcctcgca gggcgacggc gggggagtcc gggtccccca gggcgtagcg
    24421 gatgttcacg ccttcggcgc ctttgcggcg gagaacggcg gtgaagtcgg cgtgcccgtc
    24481 ggggaggaac aggccagcga tgacgaggac gtcgacctgg tgacgcgcac cggcgaacag
    24541 cgtccgccac agctcggcgg gaacggcggc gcggctgggg tagacgcgca cgacatcgct
    24601 cggcacgtcc gcggccggcg acccgggctc ggtccggggc tcggggacgg cgcccggtct
    24661 ttcggcaagc ccgatgcgtc cgcgggggat gccgatgccg tcggcgatgc gctcgaagat
    24721 ctccaggctc gtgacctggc ggcggccgtt catgatgtcg ctgacgtggg actgcggcag
    24781 gccgcacacg gcggctatct gcgtctgggt ggcgccggtc cactggcggt agatcttgaa
    24841 gacggtgccg atgtcgcggc gggcgagtgc gtcggccatc tcgggtcgct cccagagtcc
    24901 cggcggggtc tggggtaacg gacgacggac ggacaccatg gcggcctccg gacggtaggt
    24961 gctccgaccg tctgtcctcg atcgggcgcg cagagcatat ccggtctccg tatagatcgg
    25021 aagtctcggt gtatacggcc ggcggccttc cgtgaccggc tgtccggttg gacggtgggc
    25081 gggcgtcggt tccgctgcgc gacggacacc tgttgcgggc cggttccggc gctttgtcgc
    25141 acgccaccga ccagtggagg acggatcgtg atgttcgaca gggggagtgg aggtgacccg
    25201 ggtccgccgc tgttcggcat cgtccgcttc gagccgggcg gggaccgccg ggtacgggac
    25261 acggtcatca ccttccccgg ggcgacagcg gcggatctgt tcgcgatcga acagggctgg
    25321 cacgac
//
