LOCUS       NC_007777              27030 bp    DNA     circular CON 05-SEP-2024
DEFINITION  Frankia casuarinae, complete sequence.
ACCESSION   NC_007777
VERSION     NC_007777.1
KEYWORDS    RefSeq.
SOURCE      Frankia casuarinae
  ORGANISM  Frankia casuarinae
            Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
            Frankia.
REFERENCE   1  (bases 1 to 5433628)
  AUTHORS   Normand,P., Lapierre,P., Tisa,L.S., Gogarten,J.P., Alloisio,N.,
            Bagnarol,E., Bassi,C.A., Berry,A.M., Bickhart,D.M., Choisne,N.,
            Couloux,A., Cournoyer,B., Cruveiller,S., Daubin,V., Demange,N.,
            Francino,M.P., Goltsman,E., Huang,Y., Kopp,O.R., Labarre,L.,
            Lapidus,A., Lavire,C., Marechal,J., Martinez,M., Mastronunzio,J.E.,
            Mullin,B.C., Niemann,J., Pujic,P., Rawnsley,T., Rouy,Z.,
            Schenowitz,C., Sellstedt,A., Tavares,F., Tomkins,J.P., Vallenet,D.,
            Valverde,C., Wall,L.G., Wang,Y., Medigue,C. and Benson,D.R.
  TITLE     Genome characteristics of facultatively symbiotic Frankia sp.
            strains reflect host range and host plant biogeography
  JOURNAL   Genome Res 17 (1), 7-15 (2007)
   PUBMED   17151343
REFERENCE   2  (bases 1 to 5433628)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Goltsman,E.,
            Martinez,M., Schmutz,J., Larimer,F., Land,M., Kyrpides,N.,
            Lykidis,A., Francino,P., Benson,D.R., Huang,Y., Mastronunzio,J.,
            Bickhart,D., Niemann,J., Rawnsley,T., Tisa,L.S. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (19-JAN-2006) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000013345.1-RS_2024_09_05
            Annotation Date                   :: 09/05/2024 02:41:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,755
            CDSs (total)                      :: 4,702
            Genes (coding)                    :: 4,516
            CDSs (with protein)               :: 4,516
            Genes (RNA)                       :: 53
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 186
            CDSs (without protein)            :: 186
            Pseudo Genes (ambiguous residues) :: 0 of 186
            Pseudo Genes (frameshifted)       :: 53 of 186
            Pseudo Genes (incomplete)         :: 162 of 186
            Pseudo Genes (internal stop)      :: 10 of 186
            Pseudo Genes (multiple problems)  :: 37 of 186
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:46:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 944965
            Orig. end                         :: 971995
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP000249.1.
            URL -- http://www.jgi.doe.gov
            Source DNA and bacteria available from Louis Tisa
            (lst@patia.unh.edu)
            Contact: Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27030
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..27030
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27030
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:17030](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17030
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1609..2706)
                     /locus_tag="FRANCCI3_RS04090"
                     /old_locus_tag="Francci3_0814"
     CDS             complement(1609..2706)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-180). E-value:
                     3.2e-10. Score: 31.5. Matches aSDomain:
                     nrpspksdomains_FRANCCI3_RS04090_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435267.1"
                     /locus_tag="FRANCCI3_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0814"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_011435267.1"
                     /transl_table=11
                     /translation="MDQVTPTPSNLKIVVVGATGNVGTSVLAALGRSAEVGSLVGVSRR
                     TPTWTAPKTRWAQADVVTDDLAPLFQGADVVIHLAWLFQPTHNPLTTWRTNVLGSIRVF
                     EAVARAGVPALVHASSVGAYSPAAREGIVDEGWPTHGWPEAAYTREKAYLERVLDTFER
                     DYPGIRVVRLRPGFIFKREAASQQRRLLAGPLLPGRVVRPAAAPTHPATVPVLPDLPGL
                     RFQVVHSSDVADAYRLAALTGARGAFNIAADPVVDVPLLADILNARIIRMPAGLARGAL
                     ATAWHLHLVPASPQLFDAVLHLPIMDTTRARTELGWSPRHDARAAIGSFLTGLREGAGL
                     PTPPLTPSTARSRWEEVRTGMGQRA"
     aSDomain        complement(2167..2514)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRANCCI3_RS04090_NAD_binding_4.1
                     "
                     /evalue="3.20E-10"
                     /label="FRANCCI3_RS04090_NAD_binding_4.1"
                     /locus_tag="FRANCCI3_RS04090"
                     /protein_end="180"
                     /protein_start="64"
                     /score="31.5"
                     /tool="antismash"
                     /translation="DLAPLFQGADVVIHLAWLFQPTHNPLTTWRTNVLGSIRVFEAVAR
                     AGVPALVHASSVGAYSPAAREGIVDEGWPTHGWPEAAYTREKAYLERVLDTFERDYPGI
                     RVVRLRPGFIFK"
     gene            complement(2838..3071)
                     /locus_tag="FRANCCI3_RS04095"
     CDS             complement(2838..3071)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRANCCI3_RS04095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_035958017.1"
                     /transl_table=11
                     /translation="MSIAVGDRDDRSTRNGPGERAEAERGPAVFTHLRRPAAEWVSPTV
                     MDDLAARPAASLAAASLAAASLAAASLAAASE"
     misc_feature    3157..3170
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     misc_feature    3157..3173
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    complement(3159..3172)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.84"
                     /tool="antismash"
     misc_feature    complement(3258..3272)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.04"
                     /tool="antismash"
     misc_feature    3286..3303
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.72"
                     /tool="antismash"
     misc_feature    complement(3291..3305)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.73"
                     /tool="antismash"
     misc_feature    complement(3295..3311)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.68"
                     /tool="antismash"
     gene            3470..4072
                     /locus_tag="FRANCCI3_RS04100"
                     /old_locus_tag="Francci3_0815"
     CDS             3470..4072
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435268.1"
                     /locus_tag="FRANCCI3_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0815"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_236701418.1"
                     /transl_table=11
                     /translation="MARPYAAAGVLFFDEEDRILLVEPSYKPGWDIPGGFVEPGESPYS
                     ACVREVAEELGIAPPIGGLLAIDWAPCLNDGWLDSEMLAFVFDGGVLPASWRERIRLDM
                     DEIINCAFVSVDEVGGLLPSPHARRVRAAAALRGVPQRSGYLEFGNQIPESVGGSVSVA
                     SLGEPDARGAGAAQVLAGPPACGAVMMSSLANEVMEA"
     gene            complement(4354..6630)
                     /locus_tag="FRANCCI3_RS04105"
                     /old_locus_tag="Francci3_0816"
     CDS             complement(4354..6630)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435269.1"
                     /locus_tag="FRANCCI3_RS04105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0816"
                     /product="MMPL family transporter"
                     /protein_id="WP_011435269.1"
                     /transl_table=11
                     /translation="MASLARWCFRHRRLVLFLWIVALLGLGGISQVAGSSYKDAFSLPG
                     TDSQKAIDLLQRDFPAASGDSATIVLHSDKTRITNRAISDRASEMLGELAKVPHVTGIT
                     SPYGPRGAAQISKDGHTAFATVDFDLQGIELPKDDIQRFVDTARGYGGDDLQVEATGQI
                     VSIIEQQQQSYSELIGIIAAAIILFVAFGSLLAVTLPLITAIMALGVGSILIILLSHVL
                     TIAEFSPVLATLIGLGVGIDYALFIVNRHRIGLRAGKSPEEATVTAVNTSGRAVLFAGM
                     TVCIALLGMFALGVSFLYGVAISAAVAVAMTMTAAVTLLPALLGFYGMKVLNRRDRRRL
                     AEEGPVHESTSGFWWHWAKRLEGRPQLFAVVSAVVIAVIAIPFLSLRLGSSDLGNGDTA
                     KTTKRGYDLLAEGFGPGFNGPFSIVAEIHSPQDTASLRAVVAAARATPGVASVSAPRPS
                     PNGQAAIATLYPTTSPQAEATSKLLNQLRDHVIPQANQAGTGIYVGGITATFEDFSSTL
                     SGKLPLFIGIVVLLAFLLLVAVFRSLLVPLTASLMNLLAVGAAFGVVVAVFQWGWGASL
                     FSISGGPVEAFIPVILFAILFGLSMDYEVFLVSRMHEEWTARRDNRIAVSLGQAETGRV
                     ISAAGAIMILVFASFILGDERVIKLMGLGLSTAILIDAFIIRTVLVPSLMHIFGTANWW
                     VPAWLDRVLPRISVESAEDLEEIRHTPLPEDAVAGRPAAGGPVRPLPGQAAREERSSRT
                     GEPMR"
     gene            6789..7787
                     /locus_tag="FRANCCI3_RS23150"
                     /old_locus_tag="Francci3_0817"
     CDS             6789..7787
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009740221.1"
                     /locus_tag="FRANCCI3_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0817"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_011435270.1"
                     /transl_table=11
                     /translation="MTEPTSPDPASLDPRGDTRSRILAAAMSLFSEQGYAGTSVRDISE
                     RLGVTKAALYYHFPSKESILDALLEPFVSELGRLVDLVRQSPPPPPRIIIERFVEALAG
                     PGGVLLVFADDPSVIHRKIGKSDILSLQQALVHGLAGPAPTHLGLLRAYCAVGSLRGGI
                     IGMAIERAQAAARQSTSADEERRSGAGEAVTCSERIRVLVSQVSRTFTPLVSAAEQGEI
                     VAAALAALGDDPADSVSVSAAGSGGCGAVGDEGHESDRSPSGADLTGSRDAPVADAGPV
                     ADAGPVADAGPVADAGPVETSCPAHEERPACREAAAPHRSPAPDLASVRLH"
     misc_feature    complement(8753..8770)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.06"
                     /tool="antismash"
     gene            8782..9561
                     /locus_tag="FRANCCI3_RS04115"
                     /old_locus_tag="Francci3_0818"
     CDS             8782..9561
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (15-179). E-value: 1.4e-11.
                     Score: 36.6. Matches aSDomain:
                     nrpspksdomains_FRANCCI3_RS04115_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013427024.1"
                     /locus_tag="FRANCCI3_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0818"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_085014068.1"
                     /transl_table=11
                     /translation="MALRAGSVVSTWPPRTAVITGASSGIGREAALLLAADRCRSLLVG
                     RNGAALDEVAAATEGHRIAVDLSSPGSELMVSSRATELLGEVDLLVCSAGLGAAGPFEV
                     MSPAAIAELVTVNVLSPMMLVRAMLPAMLDRGQGRILLVGSIAGALGVRGEVAYSATKA
                     ALLGFADALRSEVAGRGVTVTLCLPGVVDTPFFHRRGAPYVRRWPRPIPAGLVAQRMLA
                     ATGRGDAEIWVPRWLLGAVRVHGAIPSVYRRLAGVFG"
     aSDomain        8827..9318
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRANCCI3_RS04115_PKS_KR.1"
                     /evalue="1.40E-11"
                     /label="FRANCCI3_RS04115_PKS_KR.1"
                     /locus_tag="FRANCCI3_RS04115"
                     /protein_end="179"
                     /protein_start="15"
                     /score="36.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVITGASSGIGREAALLLAADRCRSLLVGRNGAALDEVAAATEG
                     HRIAVDLSSPGSELMVSSRATELLGEVDLLVCSAGLGAAGPFEVMSPAAIAELVTVNVL
                     SPMMLVRAMLPAMLDRGQGRILLVGSIAGALGVRGEVAYSATKAALLGFADALRSEVAG
                     R"
     CDS_motif       8833..8907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS04115_0001"
                     /evalue="6.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="FRANCCI3_RS04115"
                     /protein_end="42"
                     /protein_start="17"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VITGASSGIGREAALLLAADRCRSL"
     CDS_motif       9205..9300
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRANCCI3_RS04115_0002"
                     /evalue="2.30E-03"
                     /label="PKSI-KR_m4"
                     /locus_tag="FRANCCI3_RS04115"
                     /protein_end="173"
                     /protein_start="141"
                     /score="10.5"
                     /tool="antismash"
                     /translation="LVGSIAGALGVRGEVAYSATKAALLGFADALR"
     misc_feature    9490..9492
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11074
                     /gene="hpnC"
                     /locus_tag="FRANCCI3_RS04120"
                     /old_locus_tag="Francci3_0819"
     CDS             10001..11074
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435272.1"
                     /locus_tag="FRANCCI3_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0819"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_011435272.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.2e-43,
                     bitscore: 146.2, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 4.5e-44, bitscore:
                     148.8, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIDARTSPSRTPAQPAATGLATPAEQLLRAAPAENFPVSPFVL
                     PAAVRFHFNALYAFSRLVDNLGDEAAGDRLALLDRLSADLEVIWTGGQPELPVLRLLAR
                     TVRDCDLPAEPFQRLVEANRQDQRVTRYETFDDLVRYCTLSADPIGRMVLGVFGLATPD
                     RVVLSDRVCTALQLAEHWQDVAEDLAAGRIYLPLEDLDTFGVTEADLRASVASPAVRHL
                     MAFEVARARTVIDQGAPLVSMVPGRLRLALAGFVGGGRAALDAIRRADYDVLGGPPKAT
                     KPRVAEFALAALARSLAPGASAVAHTAAAVATATSAAGAWPGSGSGSTAHGGTAATSTQ
                     AGVPAAQSVLPEMGEVR"
     gene            11071..11985
                     /gene="hpnD"
                     /locus_tag="FRANCCI3_RS04125"
                     /old_locus_tag="Francci3_0820"
     CDS             11071..11985
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435273.1"
                     /locus_tag="FRANCCI3_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0820"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_011435273.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.1e-49, bitscore:
                     166.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.4e-65,
                     bitscore: 217.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAAQFPAGRPTVAEAYAACEAVTKEAARNFSYGIRLLPAEKRG
                     ALSAVYALARRLDDIGDGDLPEEAKFAGLAQVRAEVEELGTNSSDDPVFVALADAARRF
                     PIPLEAFIELADGVESDVRGTTYDTFDDLVGYCRLVAGTIGRLSLGIFGSERATSHRDA
                     SGVADALGVALQQTNILRDVREDLLGGRIYLPRQELKAAGVELEVDATGRLGGPPDALI
                     AYLRTSAQRAEEWYGRGLVLLDLLDRRSAACCGAMAGIYLRLNRRIKTDPSAVLDRRLA
                     LPGWEKAVVAARSLAGRPEMRAA"
     gene            11982..13691
                     /gene="hpnE"
                     /locus_tag="FRANCCI3_RS04130"
                     /old_locus_tag="Francci3_0821"
     CDS             11982..13691
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435274.1"
                     /locus_tag="FRANCCI3_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0821"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_011435274.1"
                     /sec_met_domain="DAO (E-value: 5e-08, bitscore: 31.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGAGADVAPAWGTRPAGRTDERPHLAVVGGGLAGMAAALLAVD
                     SGARVTLLEARPRLGGATTSFRRGQLWIDTGQHVFMRCCTAYRGLLQRLGVEHLTTLQS
                     RLDVPVLLGDSLTRTRLRRTRVPLPAPLHLAPALLGYQALPIAERLRAGLAAFQLGRLD
                     QRSPAVDEQSFGTWLSTHGQGPAATKALWELLTVATLNVPAADASLGLAAKVVRTGLLE
                     GAAAGDLGWAEVPLSRLHGDAAMETLTAAGADVRTGVKVRSITAAGSGWELAVTAGGTG
                     RGAAVPGTDDRGVLRADAVVLAVPPPAAASLLPAGAEPEAARLRELGDSPIINVHMIYP
                     RPVIDGPFLAVVDSPIQWIFDRTVSSGLAAAGPPGAQYLALSQSAAEPWVDRPANELRT
                     LFVEEMARLFPAARAAGPLEVFVTRERTATFRQVPGSLALRPGASTGLTGFALAGTWTD
                     TGWPATMESAVRSGLTAVRENLAGMGVDVNEPRGPGPQARRTDGRLPEQVGESVPVGTE
                     SVSAPGGGATAAQVRDPQDPRGDNAVPAGSAAVVRPLPSGQPRHTSTGGFPV"
     gene            13688..14704
                     /locus_tag="FRANCCI3_RS04135"
                     /old_locus_tag="Francci3_0822"
     CDS             13688..14704
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018639661.1"
                     /locus_tag="FRANCCI3_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0822"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_011435275.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.8e-62, bitscore:
                     206.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMTVPDAIERGRTLTVPALRATVDRLHPRLRHVVAYHRGWVDAE
                     GAPLSGGGGKLVRPALALLSAQAAGAPAETGLPAAVAVELVHDFSLLHDDLMDGDTERR
                     HRPTAWTIFGADGAILAGDALLGLATQVLLEVEGEPGRRAALILGAGVQDLVRGQAEDL
                     MFEKRSDVSVAETLHMEDGKTGALLACSASLGAVLAGAGDDMVNALAEYGSRLGTAFQL
                     IDDLLGIWGDPSVTGKPVLSDLRSRKKSVPVVVALEAGGAAAEELRAFLTGTGESTEAE
                     LTHIADLIERAGGRDWTTAEADGQLKACENVLRSLSMPAEIEAELLALARFVTERDR"
     misc_feature    complement(14760..14780)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     gene            14805..17030
                     /locus_tag="FRANCCI3_RS04140"
                     /old_locus_tag="Francci3_0823"
     CDS             14805..17030
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009740215.1"
                     /locus_tag="FRANCCI3_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0823"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_011435276.1"
                     /sec_met_domain="T2TS (E-value: 5.9e-142, bitscore: 472.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTSDPSPAAPKAAKSSKRVNIPAPATPDAYGISRSSPPLSGGG
                     VSGGGVSGGGAATADGTPPTTQTSVDPDLAAAMTAANQARDHLLGLQSEEGWWKGDLET
                     NVTIDAEHLFMKQFLGIRTEEETEPIARWVRSQQLADGGWATYYGGPAELSTTVEAYIA
                     LRLAGDEPDAPHMAAAAALIRSQGGVAAARVFTRIWLATFGEWSWDDVPVLPPELIFLP
                     SWFPLNVYDFGCWARQTIVALTIVGSLRPVRDLGFSIDEIKVAAPVTPPKPAPLHSWEG
                     AFERLDAILHRYERRPIKVLRTLALRRATEWVVARQEADGCWGGIQPPWIYSVMALHLM
                     GYPLNHPVIATAFRGMERYIIRRETPEGPTAQIEACQSPVWDTALAVVALSDAGVPADH
                     PAMVRAGRWLVDEEVRVAGDWAVRRPALAPGGWAFEFDNDFYPDTDDTAEVVLALRRLL
                     GGSHVTPGGTVTPSGSVTPGGTAELSPAARDRASRGLAAVDPQLAGAMRAAAARGVDWS
                     VGMRSSDGAWGAFDADNVRTLTAKIPFCDFGEVVDPPSADVTAHIVEMLADLGRSDHPI
                     TRRAVQWLLDNQEPGGSWFGRWGINHVYGTGAVVPALIAAGVPADHPAITAAVRWLLEH
                     QSPDGGWGEDPRSYDDPAWIGRGELTASQTAWALLALLAVDPHSKAVKRGVRWLCETQR
                     PDGTWDEPQFTGTGFPGDFYLNYHLYRLVFPLTALGRYVTLTGVATP"
     gene            17027..18853
                     /gene="ispH"
                     /locus_tag="FRANCCI3_RS04145"
                     /old_locus_tag="Francci3_0824"
     CDS             17027..18853
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018639663.1"
                     /locus_tag="FRANCCI3_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0824"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_023841192.1"
                     /transl_table=11
                     /translation="MNIFASAAGGDGNAGGAGDVGDGASAGDGASAATTSAAQRAVAAA
                     AGAGIRTVPASPTEIPAQESSSPSLPSAALPASVHRPAAAVVPEQEPTPVRGRARLVVA
                     AALRVEAMAAGRSGLSADTVIVRTGMGPERARKAARLVRDTGPDAVALVGLSGGLAAGI
                     EPGDVVVASEIRNADGTVAGRCAAAPLLAGDLRRLGLTVHVGPIVTVPRLVGGTARAEL
                     AATGALAVDMESAELAAGVGDVPFAAVRVIVDTAAQPLGRIDLARRGIRGLRTMRPLGR
                     PIEAWAAAVGRRQVLLAEPRAFCAGVERAIEVVERALEIYGAPVYVRKQIVHNAHVVAD
                     LASRGAIFVEELDEVPGGSTVVFSAHGVAPAVWDQAGERGLSVIDATCPLVEKVHTEAR
                     RFTARGDTVLLIGHSGHEEVDGTLGEAPGRITLVESSADVGSLDVPDPERVTYLMQTTL
                     ALDEAAEVVDALTERFPAIVGPGSTDICYATSNRQNAVRKVAEEAQLVLVVGSANSANS
                     VRLVEVSRRDGVEAHLVGDVGDVHLSWLAGVDTIGISAGASAPPSLVNELLTALSGLGA
                     TDVSVRSVGTETLAFHLPKELRRPAPAPVPGP"
     gene            complement(18940..19305)
                     /locus_tag="FRANCCI3_RS04150"
                     /old_locus_tag="Francci3_0825"
     CDS             complement(18940..19305)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435278.1"
                     /locus_tag="FRANCCI3_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0825"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_011435278.1"
                     /transl_table=11
                     /translation="MQESSDGPRACPIARTLEVVGERWSLLVIREITLGVHRFEGIRAG
                     TGAPRAVLVERLRALERAGVLERQPYQEAGARSRHEYRLTSSGRDLAPVLLALRRWGER
                     HAAPTRPPAADRGAASG"
     misc_feature    complement(19323..19341)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.38"
                     /tool="antismash"
     misc_feature    complement(19331..19349)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            19365..19940
                     /locus_tag="FRANCCI3_RS04155"
                     /old_locus_tag="Francci3_0826"
     CDS             19365..19940
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435279.1"
                     /locus_tag="FRANCCI3_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0826"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_011435279.1"
                     /transl_table=11
                     /translation="MTTTEPESARPESASGHPHDPAAWGEPRSKTITWHDPLPVAAAAA
                     SLSGLEFLSAMRDGRIPPPPISRLFDFRPVEVAPGDVVFTCLPDESAYNPIGLVHGGLV
                     CTILDTATACAVHSTLAAAVAYTSIEIKVNYLRPVRVVVGRPSRLTAHGWVTRPGRRVA
                     FAEGDVRDDQGKVVATASSTCLIMGETA"
     gene            20254..21258
                     /gene="hpnH"
                     /locus_tag="FRANCCI3_RS04160"
                     /old_locus_tag="Francci3_0827"
     CDS             20254..21258
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009740212.1"
                     /locus_tag="FRANCCI3_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0827"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_011435280.1"
                     /sec_met_domain="PF04055 (E-value: 5.8e-18, bitscore: 63.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.6e-10, bitscore: 38.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.6e-06, bitscore: 25.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVEWRYQLRIGTYLAKQKLLRRKHFPLVLELEPLFACNLSCTGC
                     GKIQHPASVLKQRMSVDDALAAVEECGAPVVAIAGGEPLMHPQIHEIVNQLVKRKKFVI
                     LCTNGLLLQKKLKNFTPSPYFTFVLHIDGLRERHDAVVEKEGTFDECVRAFHAAKAAGF
                     RVGSNSTFFNNDSPQDVIDILTFLNDDLKVDQIQLSPGYAYEKAPDQEHFLGVQETREM
                     FSKVFADGRRKKFRLNHSPVFLDFLEGKRELSCTAWGIPSYSLFGWQKPCYLMSDGYVS
                     SYKELVETTDWDAYGRGKDPRCANCMAHCGYETSAVLATMGSLKESIRAARSV"
     gene            complement(21453..22130)
                     /locus_tag="FRANCCI3_RS04165"
                     /old_locus_tag="Francci3_0828"
     CDS             complement(21453..22130)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435281.1"
                     /locus_tag="FRANCCI3_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0828"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_011435281.1"
                     /transl_table=11
                     /translation="MTRSRRTEQTADTRQALISAARRRFAEQGFASTGTEEIVADAQVT
                     RGALYHHFRDKAALFRTVMEQVATEVAEQLVAGELARDAELPSDAWTQLRSGFQSLLDI
                     STADSDFQRIVLVDGPAVLGNDAWDALVEKHGYRLLSEWLERAMAEDRIDPLPVVPLTR
                     LVAALLSEASIYTAGAADPDTARLEVGTVLDRLLRGLGRGGDLAEQPPVSADGGAGSRG
                     TAG"
     misc_feature    complement(22309..22322)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.57"
                     /tool="antismash"
     misc_feature    22344..22358
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            22597..24069
                     /locus_tag="FRANCCI3_RS04170"
                     /old_locus_tag="Francci3_0829"
     CDS             22597..24069
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435282.1"
                     /locus_tag="FRANCCI3_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0829"
                     /product="glycosyltransferase"
                     /protein_id="WP_235462964.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.7e-17,
                     bitscore: 60.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLLWVAVASLLAWLYLTVGHGFFWRTDQRLPSRQAPTAWPSVA
                     IVVPARDEADVLPVTLPTLLAQDYPGPVQLILVDDGSTDGTTEVARDLAEQAATRGETN
                     VTPAMTTSTEPPTGWTGKLWALRRGIECAGDVDFLLLTDADISHRPGSLTALVESATSQ
                     KLDMVSQMAVLRVQTGWERLIVPAFVHFFAMLYPFRWSNRPGSRVAAAAGGCSLIRREA
                     LAAAGGLAEVRGAVIDDVAIARIIKRSGGRTWLGLAEQVHSQRPYPRLADLWKMVSRSA
                     YAQLRHSPSLLVGTVLGLSLVFVIPVVATIVGIVTGDVATALVGGIAWLIMTVTYLPMT
                     RYYCQPLPLALLLPGVAVLYLAMTVDSARLKRAGRGAAWKGRTYQDHGAPAAAPEYPNG
                     PGERREGSVAGPPDSGGSSASAGGSSALPSASSTVPATPLVMATSSAVPAPAVAPASPT
                     PTSIPTPTPTRWPASSSASPPVRGGSTDQPRT"
     gene            complement(24349..25308)
                     /locus_tag="FRANCCI3_RS04175"
                     /old_locus_tag="Francci3_0830"
     CDS             complement(24349..25308)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435283.1"
                     /locus_tag="FRANCCI3_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0830"
                     /product="urease accessory protein UreD"
                     /protein_id="WP_011435283.1"
                     /transl_table=11
                     /translation="MAAMRRGVILGGVAAGPEGPLVTAARTGRTAVRARAVIRVESAPD
                     GTARLIELRSDVPIVLRQTGASPGRTRAPSTVPALSADALPTATVHLVNATAGPLAGDD
                     LGLDISVGSGVRLVVRSVAATVALPGHGPGPSRFTVSARVAPGGALDFAPEPTVAARGS
                     DHLLVTDVHLATTAWLRLREEIVLGRFGETTGSIRSTLRVDMDAHAEVDPPSEPTPLLR
                     QDLVLGPEIPGLTGPALLGSARALGSLLVAGPDPVGSPAARRESVPAKRAESGAQAAVA
                     DGVALLPLAGPGYLISALAENAVTLRRRLEQGPAPATV"
     gene            complement(25451..26248)
                     /locus_tag="FRANCCI3_RS04180"
                     /old_locus_tag="Francci3_0831"
     CDS             complement(25451..26248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011435284.1"
                     /locus_tag="FRANCCI3_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Francci3_0831"
                     /product="urease accessory protein UreF"
                     /protein_id="WP_011435284.1"
                     /transl_table=11
                     /translation="MTIEGDTARDGGTEDVAGPTGRSGRRATLLVLADGRMPTGGHAHS
                     GGVEAAVTDGSLANLSDLAAFLVGRLTTTGLVAAAFAAAACRAGTQPGPATRAPHADHV
                     PTASVTPVTIVTPTTIATLDAELDARMPSPAQRDASRAQGRTLLRAGRAAWPVPPGPRA
                     PHHPCALGMVAAGAGLRPSDAALVAAHTTVTGPATAATRLMGLDPLAVTAVLARLTDEV
                     EAIALAGAEASRRPPRLLPAVTGIRLDLLAERHRTTALRMFTS"
ORIGIN
        1 ggcgaccacc aacggtcaga cagcggccta cctcggcggc ttcctgctgg tgatgctggg
       61 cctggtggtc ggggggccgt ggctcaccat ggccgccgcc cgggtagtcg cacggcgtac
      121 cagccgtccg gcgactctga tcgcggcgcg ccggctcgcg gacgacccga aggctggttt
      181 ccgttcggtc agcggactgg tcctggccct gttcgtcacc acggcgacgg tcagtgtcat
      241 cggaaccatc aaccacaacc gcggggtgct cagcggtgat ccgcagaccc gggtcgcggt
      301 agtggacggt gcgcagcccg gtgacccgcc gatgacaggc gccgtgccgg accggctcct
      361 cgcggacatc cgggcagtcc cgggcttccg gggcctcggc atcgtccacg ccaaccccca
      421 caggatcgga atggacccgg cggatccccg gccatgggcg cccggcctgg tggtctgcac
      481 cgacctggtg caaatcccgg tcatcggccg ctgcccaccc ggggtgggcg tcgcggccgt
      541 cccgctcttc acgttcctcg acgtccagtc gaacaacgtc aagcagtggc cctccgccgc
      601 gatctcccgg gagcaggccg ccacgctgcc cgtacagatg ctctacgtga ccaccgacgg
      661 gtcgacggcg gccatggagc agacccggac cctgctgacc aggacctacc cgaactacat
      721 ggcccggacg gtcaacgact ggggctccca ccagcaacag gagttggcca gctggcgcca
      781 gctggccaac gtggtgctgc tgaccaccct gccgatcgcg ggcgccagcc tcgccgtcag
      841 catcgtcgcg ggcctgtccg aacgcaggcg ccccttcgcg atcctgcggc tcaccggcgc
      901 gcccctacgg ctgttgcaac gagtcatcgg cctggaaagc gcgctgccgc tgctggcagg
      961 agccgccctc gcgatcggga caggcttcgc ggcggcggcc atgttcctga aatcccagat
     1021 gaaatacgat ctgatcttgc caggcgaggc gtactacacg ctcgtcgtcc tcggtctggc
     1081 cgcggcgctg ggaatcatca cctcgaccct tccactgctc aggcggatca caggctcgga
     1141 gaccgcgcgt aacagctgat gcttcccgcc acgcccccat cgcgacggag cccaactgtg
     1201 gcctgccctg tctgtcgtcc ggattcggtg gatgagcgac gcctggaccg ttcccgcttc
     1261 ggtggacacc cggattagct gtccgatccg tcgggagagc gagcgatggg cgcgacacgc
     1321 cgcagattca ccgaggagta caaggagcac gcggtcgttg tactcggccg ggttgtggac
     1381 accgtccaca tcccccagca gacgcccgac gaccacccgg ttcacctccg ggaacgcctc
     1441 ccaagacggc acgctcgccg gtgcttcctg gctctggggg gcacggcagc ctctgcggac
     1501 accacatacc tccttcgccc acctcggccc gggcctcaca cagtcgccgc acgaccgtga
     1561 ccaccgccaa caggccgtca acccctacga caggggtagc gccccgcgtc aggcccgctg
     1621 ccccatgccg gtgcggacct cttcccaccg gctccgcgcg gtgcttggcg tgagcggggg
     1681 tgtgggcagg cccgcgccct cgcgcaggcc ggtgaggaag ctgccgatcg cggcgcgggc
     1741 gtcgtggcgg ggcgaccagc cgagctccgt ccgggcccgg gtggtgtcca tgatcggtag
     1801 atgcaggacg gcgtcgaaga gctgcgggga ggcgggcacc agatgcaggt gccaggcggt
     1861 agccagagcg ccccgggcca ggccggccgg catccggatg attctcgcat tgaggatgtc
     1921 ggcgagcagg ggtacgtcga ccaccgggtc ggccgcgatg ttgaaggcgc cgcgggcccc
     1981 ggtcagggcc gccaaccggt aggcgtccgc gacgtcggag gagtgcacca cctggaagcg
     2041 tagccccggc agatccggca gcacggggac cgtcgcgggg tgcgtgggcg ccgctgccgg
     2101 ccgtaccacc cggccgggta gcaacggccc ggcgagcagg cgccgttgct ggctggcggc
     2161 ctcccgcttg aagatgaacc cgggccgcag ccgtaccacc cggatgcccg gatagtcacg
     2221 ttcgaaggtg tcgaggaccc gctccagata cgccttctcc cgggtgtagg cggcctcggg
     2281 ccagccgtgg gtcggccatc cctcgtcaac gatgccttcc cgggcggcgg gcgagtaggc
     2341 gccgaccgac gaggcatgca ccagcgcggg cacgccggct cgggcaacgg cctcgaacac
     2401 gcggatggat cccaggacgt tggtccgcca tgtggtcaag gggttgtggg tgggttggaa
     2461 caaccaggcc aggtggatca cgacgtcggc gccctggaac agcggggcga ggtcgtccgt
     2521 gacgacatcg gcctgtgccc accgggtctt cggcgccgtc catgtcgggg tgcggcggga
     2581 caccccgacc agggagccga cctcggccga ccggccgagg gctgccagca cgctcgtgcc
     2641 gacattcccc gtggctccca ccacgacgat cttcaggttg ctcggggtcg gcgtcacctg
     2701 atccacctca tccacctcct gcggtcggcc gggaatcccc cgtcggggga agcggtctcc
     2761 cttcggagga acggataccc gccgacgggc gtccagatgc agccctcagc tctcgatgag
     2821 ttgcggtgcg ccgtccgtca ctccgaggcg gccgcgaggg aggcggccgc gagggaggcg
     2881 gccgcgaggg aggcggccgc gagggaggcg gccggtcttg ccgcgaggtc gtccatcacc
     2941 gtgggggaga cccattcggc ggccggccgg cgcaggtggg tgaagacggc tggtccgcgc
     3001 tccgcctcgg cccgttctcc cggtccgttc cgcgttgacc ggtcatctct gtcaccgacc
     3061 gctatcgaca caattctttc tgtcgtatcg tcgtccggtc cgcgttgcgg atatggatcg
     3121 gcggggtaac cgcacccgcc ctccttgccg gttcgtcttt attattttta ccttagttcc
     3181 gcgaaacgct ggcgggtcgc gtcccttcgt ggtcgcctat cgttagtggt ccaccgcgtc
     3241 gcccaccact cggcggcagg aacatcaatt ccgttcgtca gtactatgtg aagtgtgtga
     3301 taatatgaag aaggatcttg acttttccct agtcgaccgg gctctgtcgg acccggccgg
     3361 cgtacccggt gacggtctga tgctgcggtc ggcgatgtcc tcgaagccgc cggccacccc
     3421 acggcagcgt cctgaccacg gcaccgaggc gagcttgaac cgacctccga tggcgcgacc
     3481 ctacgctgcg gcgggtgtcc tgttcttcga tgaagaagac cgcatactgc tcgttgaacc
     3541 gtcgtacaag ccgggctggg acattccggg aggctttgtc gaaccggggg aatcgcccta
     3601 ctcggcgtgc gtacgggagg tcgccgagga gctcggtatc gccccaccga tcggtggtct
     3661 gctcgcgatc gactgggcgc catgtcttaa cgacgggtgg ctcgacagcg agatgctggc
     3721 cttcgtcttc gacggcggtg tgctgcctgc ctcatggcgg gagcgcatcc ggctggacat
     3781 ggacgagatc atcaactgcg cgttcgtctc cgtggacgag gtgggcgggt tgctgccgtc
     3841 cccgcacgcg cgacgggtcc gtgccgccgc ggccctgcgg ggggtgccgc agcgtagcgg
     3901 atatctggag ttcggtaatc agattcccga gtccgtcggt ggttcggtga gcgtcgcgtc
     3961 gctcggtgaa ccggatgctc ggggcgcggg cgcggctcag gtgctcgcgg ggccacccgc
     4021 atgtggtgcg gtgatgatgt ccagcttggc gaacgaggtg atggaggcat gaccgccggc
     4081 gtctcggtga ggatccggcg caccgccggt ttggcgtgac ggttgcgcac ccacgccccc
     4141 aaccgggccc gggcacaggg gaacaacgtg cccagtaccg tcgcggtcgc gctcgtggtt
     4201 ccttcgatgg cgacgaacgt gtcctcggcc ggctcaccat cctggccgat cccggcaggc
     4261 caagcgccgc ggggcgcccg ccggccaggc ggacgccccg cgggctgtca ctgttcgggt
     4321 ggtcccgcag tgtttcgggt ggtcccgtga agatcagcgc atgggctcgc cggtgcgtga
     4381 gctccgctcc tcgcgggctg cctgcccggg aagcgggcgg accggccccc cggccgcggg
     4441 acggcccgcg acggcgtcct cgggcagcgg ggtgtgccgg atctcctcca gatcctcggc
     4501 ggactcgacg gagatccgcg gcaggacccg gtcgagccag gccggcaccc accagttcgc
     4561 cgtgccgaag atgtgcatca gcgagggcac cagcacggtc cggatgatga aggcgtcgat
     4621 gaggatcgcc gtcgagagcc cgaggcccat cagcttgatc actcgttcgt caccgaggat
     4681 gaacgaggcg aagaccagga tcatgatcgc gccagccgcg gagatgaccc ggccggtctc
     4741 ggcctggccg agcgagacgg cgatccggtt gtcccggcgc gcggtccact cctcgtgcat
     4801 ccggctgacc aggaacacct cgtagtccat ggacaggccg aacaggatcg cgaagaggat
     4861 caccgggatg aacgcctcga ccgggccgcc gctgatgctg aacagcgatg cgccccagcc
     4921 ccactggaac accgcgacga ccacgccgaa ggccgccccg accgcgagca ggttcatcag
     4981 cgaggcggtc aacgggacca gcaggctgcg gaacaccgct accagcagca ggaaggcgag
     5041 gagaaccacg atcccgatga acagcggcag cttgcccgac agcgtgctgg agaagtcctc
     5101 gaaggtggcc gtgatgccgc cgacgtagat gccggtgccg gcctggttcg cctgcgggat
     5161 cacgtggtcg cgcagctggt tgagcagctt cgaggtcgcc tcggcctgcg ggctcgtcgt
     5221 cgggtacagg gtggcgatcg ccgcctgccc gtttgggctc ggccgcgggg ccgagacgga
     5281 ggcgacgcct ggtgtcgcgc gggccgccgc caccacagcg cggaggcttg ccgtgtcctg
     5341 cggcgaatgg atctcggcga cgatgctgaa cggaccgttg aaccccggtc cgaagccctc
     5401 ggccagcagg tcgtagccgc gcttggtggt cttggcggtg tcgccgttgc cgaggtcgga
     5461 cgagccgagc cgcagcgaga ggaacgggat cgcgatgacg gcgatgacca ccgcgctgac
     5521 caccgcgaac aactggggcc gcccctccag ccgcttcgcc cagtgccacc agaagcccga
     5581 ggtgctttcg tgcaccgggc cctcctcagc cagcctgcgc cggtcgcgcc ggttgagcac
     5641 cttcatgccg tagaagccga gcagggccgg cagcagggtg acggccgcgg tcatcgtcat
     5701 cgccacggct accgccgccg agatcgccac gccgtagagg aagctcacgc cgagcgcgaa
     5761 catgccgagc agcgcgatgc agacggtcat gccggcgaag agcacggcgc gcccggaggt
     5821 gttgaccgcg gtgaccgtgg cctcctccgg gctcttgcct gcgcgtaggc cgatgcggtg
     5881 ccggttgacg atgaacaggg cgtagtcgat gccgacgccc agtccgatca aggtcgcgag
     5941 gaccgggctg aactcggcga tcgtgaggac gtgggagagc aggatgatca ggatgctgcc
     6001 gaccccgagg gccatgatgg cggtgatcag gggcagagtg acggccagca acgagccgaa
     6061 ggcgacgaag aggatgatcg ccgcggcgat gatgccgatc agctcgctgt agctttgctg
     6121 ctgctgctcg atgatcgaga cgatctgacc ggtcgcctcc acctgcaggt cgtcgccgcc
     6181 gtagcctcga gcggtgtcga cgaaccgctg gatgtcgtcc ttgggcagct cgatgccctg
     6241 caggtcgaag tcgacggtcg cgaaggccgt gtgcccgtcc ttgctgatct gggcggcgcc
     6301 ccgcggcccg tatgggctcg tgatcccggt gacgtgcggg accttggcga gctcgccgag
     6361 catctcgctg gcccgatcgg agatggcacg gttggtgata cgagtcttgt cactgtgcag
     6421 cacgatggtg gcgctgtctc ccgacgccgc cgggaagtcg cgttgcagga ggtcgatggc
     6481 cttctgcgaa tcggtgccgg gcagggagaa ggcgtccttg taactacttc cggccacctg
     6541 gctgatgccg ccgagcccga gcagcgcgac gatccacagg aacaggacga gccgacggtg
     6601 ccggaagcac cagcgggcga gcgaggccac ggtttcccct cgggcgttgg tgatcggtgg
     6661 tgtcgctacc tgcgacgtca tgctgacgat ttgctgctga ttgctaccga gaaacttacc
     6721 ggtcgttcag taggtagagt tgagggtaac atccgtcgcg gactcgatcg ggggggtgta
     6781 tggccgccat gaccgagccg acatcgcccg atccggcatc gctcgatcca cggggcgata
     6841 ccagatcgcg gatcctcgcc gccgccatga gcctcttcag cgaacagggg tatgccggca
     6901 cctcggtgcg ggacatctcc gagcggctgg gagtgacgaa ggcggcgctc tattaccact
     6961 ttccgtcgaa ggagtcgatc ctcgacgctc tgctggagcc cttcgtgtcc gagttgggtc
     7021 gacttgtcga tctcgttcgg cagtccccgc cgccgccccc ccggatcatc atcgagcgat
     7081 tcgtcgaggc gctggcgggc cccggtggcg tgctgctcgt cttcgccgac gacccttcgg
     7141 tgattcaccg taagatcggc aagagcgaca tactgtccct gcagcaggcc ctcgtgcacg
     7201 ggctcgcggg gccggctccc acccatctcg ggttgctgcg cgcgtactgc gcggtcggat
     7261 ccctgcgggg ggggatcatc gggatggcga tcgaacgtgc ccaggccgcc gccaggcagt
     7321 ccaccagcgc cgacgaggag cgccgcagcg gcgcgggcga ggcggtcacc tgctccgagc
     7381 gcatccgggt ccttgtctcg caggtatcga ggacattcac cccgctggtc tccgccgcgg
     7441 agcaggggga gatcgtggct gccgccctcg ccgctctcgg tgacgatccc gccgactccg
     7501 tctccgtctc cgccgctggt tccggcggct gcggcgcggt gggtgatgag gggcatgaaa
     7561 gtgacaggtc tccctccggt gctgacctga ccgggtcacg ggatgctccg gtcgccgacg
     7621 cgggtccggt cgccgacgcg ggtccggtcg ccgacgcggg tccggtcgcc gacgcgggtc
     7681 cggtcgagac atcctgcccg gcgcacgaag aacgtcccgc gtgccgggag gccgcggcgc
     7741 ctcaccggtc tcccgcgccg gacctggcct ccgtccggct ccactgacga ctgtatgcgc
     7801 cggaccgtga gcgatccggt gcatcacccc ttcgtatcca cccaccttcg cggttcatgt
     7861 gcctcatctc actcttcaga cgttcgtaga tggtggtccg tctatttggt cgtggcaaat
     7921 gccgctttcg ctcttgtttg tctggggcgg tagggtggtc gcgtgtggag gatggatcag
     7981 cgtttggatg atgagccttc cgcctgtccg gcgcacgccg cggacgggtc gacacatctg
     8041 ccgccggagg taggtctcgg cggctttgcc tccgtcgcgg ccggtgatcc tgtggtgacc
     8101 ggatcggact gacgggaggg tgttggcgtc ggagcaggcc gaccatgacc ctgacgccgt
     8161 gtaccggcat cgagtcggca aggtgtcgtc ggcgcgtcct tcctccggag gcaatgcggt
     8221 tgtaaatagt ccgcaatacc cagtcgtcga tgtggagcca gttcgaagtc cccggaagaa
     8281 ggtctccgag agcagattcc gaatcgatcg gaccgctgtc atatcgggcg acgccggacg
     8341 gtcgggatga gggagtgtga tagggagtcc ggagtcgcgc taggcccccg ccgtccgatg
     8401 tcgcccatct gaccatggac gatccggcga cgggacggtg gaatggtggc agtcgtgagc
     8461 ccggtggcgc ggagttacca acgcgccgcg gatccggagc ccggcgttga tgagatgagc
     8521 agtggctgtt cggatcggtg ccgcccgcca gggtggccga cgcaacgatc cggccggcga
     8581 gttcgtgcca gcggaccaca ccgaatcacc ttcggtcgga ccacctcgca acgcggggcg
     8641 acgagtaggg aaagttgtag gtgacgtgca accagtgccc gcgggggaga acggcgtgag
     8701 gggaatgacc ggaagcggtg tgtcgtgagc acccggtctc gccccgcttt cggtaacgga
     8761 gtgtctacat ctctcaccgg gctggcccta cgggccggct cggtcgtctc gacctggccg
     8821 ccccggaccg ccgtcatcac gggagcatcc agcggtatcg gccgggaggc cgcgctgctg
     8881 ctggccgcgg accgatgccg gtcgctgctg gtcggtcgca acggggccgc gcttgacgag
     8941 gtggccgcgg cgaccgaggg gcaccggatc gcggtcgacc tgtctagtcc cggctcggaa
     9001 ctgatggtct cctcccgggc gaccgagctt ctcggcgagg tcgacctgct ggtgtgctcg
     9061 gcaggcctcg gggcggcggg cccgttcgag gtaatgtccc cggccgcgat cgcggagctg
     9121 gtcacggtca acgtgctgtc gccgatgatg ctggtccggg ccatgttgcc ggccatgctc
     9181 gaccgcggcc aggggcgcat cctgctggtg ggcagcatcg ccggcgcgct gggagtgcgc
     9241 ggtgaggtcg cctattccgc aaccaaggcc gctctgctcg gtttcgccga cgcgttgcgg
     9301 tccgaggttg ccggtcgcgg tgtgacggtg accctgtgtc tacctggtgt cgtcgacaca
     9361 ccatttttcc accgccgtgg cgcgccctac gtccgtcgct ggccccggcc cataccggcc
     9421 gggcttgtcg cgcagcgcat gctggcggcc accggacgcg gcgacgctga gatctgggtg
     9481 ccacgctggt tactcggcgc ggtgcgggtc cacggtgcga tcccgtcggt ctaccgcagg
     9541 ctggcgggtg tcttcggatg atccgcggcg tggtctaccc ggccgcttcc ggctctccga
     9601 ccggccctgg gggtgagcga caccgacgat gagagtgccg cggccgacgg gcggccaccg
     9661 gccgcaggcc gcccaggtgg tgccgccgga gcatcattcc gcccacggac ctgtgaggac
     9721 caaccgaagg gggccggcca ggcggagctc atcccgatac cggcccaggg ccggcccatc
     9781 tcccgtaccg gcccgcgctg atcgtgccca tgaccacccg gtgcgatccg catcctgatc
     9841 gcctcggcga gacccgggca gccaccccca ccgcggagcc ttccgaagag ccttccgaac
     9901 ccgggctctg cgggtacgtc cgcgccggtc gtggcatccg gggatgcggg atccgacccg
     9961 accgcgtccg tagtgcagac cgccatcgaa ggagaggcgt atgacagcca tcgacgcccg
    10021 aaccagccca tcacgcacgc ctgcccagcc ggccgcgacg ggcctggcaa ctcccgccga
    10081 gcagctgctg cgcgccgccc cggcggagaa cttcccggtc tcgccgttcg ttctgcccgc
    10141 ggcggttcgt ttccacttca acgcgttgta cgccttcagc cggctcgtcg acaacctcgg
    10201 cgacgaggcg gccggcgacc ggctcgccct gctcgaccgg ttgtcggcgg acctcgaggt
    10261 gatctggaca ggtgggcagc cggagctgcc ggtcctgcgc ctgctcgcgc ggaccgtgcg
    10321 ggactgtgac ctgcccgccg aaccgttcca gcgcctcgtc gaggccaacc ggcaggacca
    10381 gcgggtcacc cgttacgaga ccttcgacga cctggtccgc tactgcacgc tctcggccga
    10441 tccgatcgga cggatggtgc tgggcgtctt cgggctggcg acccccgacc gggtcgtgct
    10501 gtcggaccgg gtgtgcaccg ccttgcagct cgccgagcac tggcaggacg tggccgagga
    10561 cctcgccgcc ggccggatct acctgccgct ggaggatctg gacaccttcg gggtgaccga
    10621 ggccgatctg cgggcttccg tcgcgagtcc ggccgtgcgc catctgatgg ccttcgaggt
    10681 cgctcgggcc cgtacggtga tcgaccaggg cgctcccctg gtgtcgatgg tgcccgggcg
    10741 gctgcggctg gccctggccg gtttcgtggg cgggggccgg gcggcgttgg acgcgatccg
    10801 gcgcgccgac tacgacgtgc tcggtgggcc accgaaggcg acgaagccac gggtcgccga
    10861 gttcgcgctg gcggcgctgg cccggtcgct ggctcccgga gcgtcggcgg tggcgcacac
    10921 ggcggccgcc gtcgccaccg cgaccagcgc ggccggggcc tggccgggtt ccggttccgg
    10981 ttccacagcc cacggcggca ccgccgcgac gagtacccag gccggcgtcc ccgcagcaca
    11041 gtccgttctt ccggagatgg gtgaggttcg atgagtaccg cggcgcagtt ccccgcgggc
    11101 cggccgaccg tggcggaggc gtatgccgcc tgcgaggccg tgaccaagga ggcggcacgc
    11161 aacttctcct acggcattcg cctgctgccg gccgagaagc ggggggcgct gagcgccgtc
    11221 tacgcgctcg cccgccgcct cgacgacatc ggcgacggcg atcttcccga ggaggcgaag
    11281 ttcgccgggc tggcgcaggt ccgcgcggag gtcgaggagc tggggacgaa cagctccgat
    11341 gatccggtct tcgtcgccct cgccgacgcc gcccgccggt tcccgatccc gttggaggcg
    11401 ttcatcgaac tcgccgacgg ggtcgagagt gacgtgcgcg gcaccaccta cgacacgttc
    11461 gacgatctcg tcggctactg ccgcctggtc gccgggacga tcgggcgtct ctcgctcggc
    11521 atctttggca gcgagcgggc cacctcccac cgcgacgcct cgggggtcgc ggacgccctc
    11581 ggggtcgcac tccagcagac gaacatcctc cgggacgtgc gcgaggacct gctcggcggc
    11641 cggatctacc tgccgcgcca ggagctgaag gccgccggcg tcgaactcga ggtggacgcg
    11701 accggtcgcc tcggcggccc ccccgacgcg ctcatcgcgt acctgcggac gtcggcgcag
    11761 cgagcggagg agtggtatgg gcgtgggctc gtcctgctcg acctgctcga ccggcgcagc
    11821 gcggcctgtt gtggggcgat ggccggcatc tacctgcggc tcaaccggcg gatcaagacc
    11881 gatccgtccg cggtgctcga tcgtcggctg gcgctgcccg gctgggagaa ggcggtcgtc
    11941 gccgcccgca gcctcgcggg gcggcccgag atgagggcgg catgaccacg ggtgccggtg
    12001 cggacgtcgc gccggcatgg gggacgcggc ccgccgggcg gacggacgaa cgcccgcatc
    12061 tcgccgtcgt cggcggcggg ctcgcgggca tggccgcggc gctgctggcc gtggacagcg
    12121 gggcccgcgt gaccctgctg gaggcacgtc cccgcctcgg cggggcgacg acgtcgttcc
    12181 ggcgcgggca gctgtggatc gacaccggcc agcacgtgtt catgcggtgc tgcacggcct
    12241 accgtgggct gctgcagcga ctcggcgtcg aacacctgac caccctgcag tcccggctgg
    12301 acgtgccggt gctgctcggc gactcgttga cccggacccg gctgcgccgg acgagggtcc
    12361 cgctgccggc gccactgcac ctggccccgg cgttgctggg gtaccaggcg ctgccgatcg
    12421 ccgaacggct gcgggccggg ctcgcggcgt ttcagctcgg gcggctcgac cagcgctccc
    12481 cggcggtgga cgagcagtcg ttcggcacct ggttgtccac ccacggccag ggccccgcgg
    12541 cgacgaaggc gttgtgggaa ctgctgacgg tcgcgacgct gaacgtgccc gccgccgacg
    12601 cctccctcgg cctcgcagcc aaggtcgtgc ggaccggtct gctggagggc gccgccgccg
    12661 gggacctcgg ctgggccgag gtccccctgt cccgactgca cggcgacgcg gcgatggaga
    12721 cgctcaccgc ggccggcgcc gacgtgcgca ccggggtgaa ggtccggtcc atcaccgccg
    12781 cgggcagcgg atgggaactg gccgtcaccg cgggcgggac cggtcgcggc gcggcggtgc
    12841 ccggcaccga cgaccgcggc gtgctgcggg cggacgcggt cgtgctcgcg gtgccgccgc
    12901 ccgccgccgc gtcccttctg ccagccggcg ccgaacccga ggcggcccgg ctgcgtgagc
    12961 tcggcgactc gccgatcatc aacgtgcaca tgatctatcc tcgaccggtg atcgacggcc
    13021 cgttcctggc cgtggtcgac tcgcccattc aatggatctt cgatcgcacg gtctcctccg
    13081 ggctcgccgc tgccggcccg cccggtgccc agtacctggc gctgtcgcag tccgcggcgg
    13141 agccatgggt cgatcgtccg gcgaacgagc tgcggaccct gttcgtcgag gagatggccc
    13201 ggctgttccc ggccgcgcgg gcggccgggc cactggaggt tttcgtcact cgggaacgta
    13261 cggcgacctt ccggcaggtg cccggttcgc tcgcgttgcg tccgggcgcg tcgaccggcc
    13321 tgaccggctt cgccctggcc ggaacctgga ccgacaccgg atggccggcg accatggagt
    13381 cggccgtgcg tagcggactc actgctgtcc gtgagaacct ggccggtatg ggggtcgacg
    13441 tcaacgagcc acgcgggccg ggcccgcagg cccgaaggac ggacggacgg ctccccgagc
    13501 aggtgggtga gtcggtaccg gtaggcactg aatcggtgag cgcaccgggc ggcggcgcca
    13561 cggccgcgca ggtgcgggat ccacaggatc cacgagggga caacgcggtt cccgccggat
    13621 cggcggcggt cgtccggccg cttccgtccg gccagccaag gcacacatcc acagggggat
    13681 tcccggtatg accatgacgg ttccggatgc gatcgagcgt gggcggaccc tcaccgtgcc
    13741 tgccttgcgc gccacggtgg atcggctcca cccacgactt cgtcacgtcg tcgcctacca
    13801 ccgcggctgg gtcgacgccg agggcgcgcc actgtccggc ggcgggggca agctggtacg
    13861 cccggcgctg gcgctgctgt cggcgcaggc cgccggcgcc ccggcggaga ccgggctgcc
    13921 ggcagcggtc gccgtcgagc tggtgcacga cttctcgctg ctgcacgacg atcttatgga
    13981 cggcgacacc gagcgccgcc accggcccac ggcctggacg atcttcggtg ccgacggcgc
    14041 gatcctcgcc ggggacgcgc tgctcggcct cgcgacccag gtcctgctgg aggtcgaggg
    14101 ggagcccggc cgtcgtgcgg cgctgatcct gggcgcgggc gtccaggacc tcgtccgtgg
    14161 ccaggccgag gacctgatgt tcgagaaacg gtcggacgtc agcgtcgccg agacgctgca
    14221 catggaggac ggcaagaccg gcgcgctgct ggcctgctcg gcctccctcg gcgccgtgct
    14281 cgccggggcc ggtgacgaca tggtcaacgc cctcgccgag tacggctccc ggctcggcac
    14341 cgcgttccag ctcatcgacg acctgcttgg tatctggggt gatccctcgg tgaccggcaa
    14401 gccggtgttg tcggacctgc gttcccgcaa gaagtcggtg ccggtcgtgg tggccctgga
    14461 ggccggcgga gccgcggccg aggagctgcg ggcgttcctc accggcaccg gggagtccac
    14521 cgaggcggag ctgacgcaca tcgcggacct gatcgagcgg gccggcgggc gggactggac
    14581 caccgccgag gccgacggcc agctgaaggc ctgcgagaac gtgctccgct cgctgtcgat
    14641 gcccgccgag atcgaggcgg aactgctggc cctcgcgcgc ttcgtgaccg aacgagaccg
    14701 ctgaggagac gacgggtgag tgcagtcgcc gttcccgccc ggcccggcga tcagcacgtt
    14761 gatcgtcttc atgaccatcg catgtacgac gaggggagtc gtcgatgagc ctgacctcgg
    14821 acccgtcccc ggctgctcca aaggccgcga agagctcgaa gcgcgttaac attcccgcgc
    14881 ccgccacgcc cgacgcttac gggatctccc ggtcctcgcc accgctgtcc ggcggtggtg
    14941 tgtccggcgg tggtgtgtcc ggcggtggcg cggcgaccgc cgacggcacc ccgcccacga
    15001 cgcagacctc ggtcgatccg gacctggccg cggcgatgac cgcggccaac caggctcggg
    15061 accacctcct cgggctgcag tccgaggagg gctggtggaa gggcgacctc gagacgaacg
    15121 tcacgatcga cgccgaacac ctgttcatga agcagttcct cggcatccgc accgaggagg
    15181 agaccgagcc gatcgcccgg tgggtgcggt cccagcaact cgcggacggc ggctgggcca
    15241 cgtactacgg cggaccggcc gagctgtcca ccacggtcga ggcgtacatc gccctgcgtc
    15301 tggccggtga cgagcccgac gccccgcaca tggcggcggc ggccgcgctc atccgctccc
    15361 agggcggggt ggcggccgcc cgggtgttca cccgcatctg gctggcgacc ttcggcgagt
    15421 ggtcctggga cgacgtgccc gtcctgccgc cggaactgat cttcctgccg tcctggttcc
    15481 cgctgaacgt ctacgacttc ggctgttggg cccgccagac gatcgtcgcg ttgacgatcg
    15541 tcgggtcgct ccggcccgtg cgcgacctcg gcttcagcat cgacgagatc aaggtcgcgg
    15601 cacccgtgac gccgccgaag ccggccccgc tgcacagctg ggaaggcgcc ttcgagcggt
    15661 tggacgcgat cctgcaccgc tatgagcgcc ggccgatcaa ggtgctgcgc accctggcgc
    15721 tgcgccgggc caccgagtgg gtcgtcgccc gccaggaggc cgacgggtgc tgggggggca
    15781 tccagccgcc gtggatctac tccgtcatgg cgctgcatct catgggatac cccctcaacc
    15841 acccggtgat cgccacggcg ttccggggaa tggaacgcta catcatccgg cgcgagaccc
    15901 cggaggggcc gaccgcccag atcgaggcat gccagtcgcc ggtctgggac accgcgctcg
    15961 cggtggtcgc gctctcggac gccggcgtcc ccgccgacca tcccgcgatg gtgcgggccg
    16021 gccgctggct ggtcgacgaa gaggtcaggg tggccgggga ctgggcggtc cgccgtccgg
    16081 cgctcgcccc tggcggctgg gcgttcgagt tcgacaacga cttctacccg gataccgacg
    16141 acaccgccga ggtcgtgttg gcgctgcgtc gcctgctcgg tggcagccat gtcaccccgg
    16201 gtggcaccgt caccccgagt ggcagcgtca ccccgggcgg caccgccgag ctctcgccgg
    16261 ccgcgcgtga ccgcgcctcc cgcggcctcg cggcggtcga cccgcagctg gccggggcga
    16321 tgcgcgcggc cgcggcccgt ggggtcgact ggagcgtcgg catgcggtcg tcggacgggg
    16381 cctggggtgc cttcgacgcc gacaacgtgc ggacgctgac agcgaagatc ccgttctgcg
    16441 acttcggcga ggttgtcgac ccgccgtcgg cggacgtcac cgcccacatc gtggagatgc
    16501 tggccgacct cggccgttcc gaccacccga tcacccggcg ggcggtgcaa tggctgctgg
    16561 acaaccagga accgggcggc tcctggttcg gccggtgggg gatcaaccac gtctacggca
    16621 ccggcgccgt ggttccggcg ctgatcgccg ccggcgttcc cgccgaccac ccggcgatca
    16681 cagccgcggt gcgctggctg ctggagcacc agtcgcccga cggtggatgg ggtgaggacc
    16741 cacgctccta cgacgatccg gcctggatcg gtcggggtga gctcaccgcc tcgcagaccg
    16801 cctgggccct gctcgcgctg ctggctgtcg acccgcacag caaggccgtc aaacggggag
    16861 tgcgctggct gtgcgagacc cagcggccgg atgggacctg ggacgagccc cagttcaccg
    16921 gaaccggttt ccccggtgac ttctacctca actaccacct gtaccggctg gtcttcccgc
    16981 tgaccgcgct cggtcggtac gtgaccctca ccggggtggc cacgccatga acatcttcgc
    17041 atccgcggcc ggcggcgacg ggaacgccgg gggcgcaggg gacgtcgggg acggcgcgtc
    17101 cgccggggac ggcgcgtccg ccgccacgac gagcgcggct cagagggccg tcgccgcggc
    17161 cgcgggtgcc gggatcagga ccgttccggc ctcccccacc gagatcccgg cgcaggagtc
    17221 gtcgtcgccg tccctgccgt cggccgcgct cccggcgtcg gtccaccggc cggccgcggc
    17281 ggtcgtcccg gagcaggagc caacccccgt gcgcggtcgg gcgcggctgg tcgtcgcggc
    17341 ggccctgcgg gtcgaggcaa tggccgccgg tcggtcgggc ctcagcgcgg acaccgtcat
    17401 cgtgcgcacc ggcatgggtc cggaacgggc gcgcaaggcc gcccggctgg tgcgcgacac
    17461 aggcccggac gccgtcgccc tcgtcggtct ctccggggga ctggcggccg ggatcgagcc
    17521 cggtgacgtc gtcgtggcca gcgagatccg caacgccgac ggcaccgtcg ccggccgttg
    17581 cgcggccgcg cccctgctgg ccggcgacct gcgccggctc gggctcaccg tgcacgtcgg
    17641 cccgatcgtc accgtgccgc ggctcgtcgg cggcacggcc cgcgcggaac tcgccgcgac
    17701 cggggccctt gccgtcgaca tggagtccgc ggagctggcg gcgggagtcg gcgacgtgcc
    17761 gttcgccgcc gtccgcgtca tcgtcgacac ggcggcgcag ccgctgggac gtatcgacct
    17821 ggcccgccgc ggaatccgtg gtctgcgcac gatgcgtccg ctcgggcgcc ccatcgaggc
    17881 gtgggccgcc gcggtcggcc gtcgccaggt tctgctcgcc gagccgcggg cgttctgcgc
    17941 cggcgtcgaa cgggcgatcg aggtcgtcga gcgcgccctg gagatctacg gcgcgccggt
    18001 ctacgtccgt aagcagatcg tgcacaacgc ccacgtggta gccgacctgg ccagccgtgg
    18061 agcgatcttc gtcgaggagc tcgacgaggt gcccggcggc tcgacggtcg tcttctccgc
    18121 gcacggagtg gccccggccg tctgggacca ggcgggcgag cgcggcctgt ccgttatcga
    18181 cgccacctgt ccgctggtgg agaaggtgca caccgaggcc cgccggttca ccgcccgcgg
    18241 ggacaccgtg ctgctcatcg gccattccgg ccacgaggag gtggacggaa ccctcggcga
    18301 ggcgcccggc cgcatcacgc tggtcgagtc ctcggccgac gtcggctccc tcgacgttcc
    18361 cgatcccgag cgcgttacct acctcatgca gaccacgctg gccctggacg aggccgcgga
    18421 ggtcgtcgac gcgttgacgg agcggttccc ggcgatcgtc gggccgggct ccaccgatat
    18481 ctgctacgcg acctcgaacc ggcagaacgc ggtccgcaag gttgccgagg aggcccagct
    18541 cgtcctcgtc gtcggctcgg ccaacagcgc gaactccgtg cggctcgtcg aggtgagcag
    18601 gcgcgacggc gtcgaggcgc atctggtcgg ggacgtcggg gacgtgcatc tgtcctggct
    18661 tgccggcgtg gacacgatcg gcatctcggc cggcgcctcg gccccgccgt ccctcgtcaa
    18721 cgagctcctg accgcgttgt cgggtctcgg cgcgacggac gtctcggtgc gttccgtcgg
    18781 caccgagacg ctcgccttcc acctgcccaa ggaactgcgc cgaccggccc cggcgcccgt
    18841 tccagggcca tagtgcgccc ggctcccggg cggtcccgag gtgcggcccg gcgagggcga
    18901 agccggtggc gtcgcccggg cgacacggtg gggttcggtt cagccggatg cggcgccgcg
    18961 atcggccgcg ggcggccggg tcggtgcggc gtgccgctca ccccaccggc gcagggccag
    19021 caggaccggt gccaggtccc ggccggagga cgtcagccgg tactcgtgcc gggaccgggc
    19081 gcccgcctcc tggtacggct gacgctccag cacccccgcg cgctccagcg cccgcagccg
    19141 ctcgaccagc acggctcggg gcgccccggt gccggcccgg atgccctcga agcggtggac
    19201 ccccagcgtg atctcccgga tgaccagcag ggaccagcgc tcacccacga cctccagcgt
    19261 ccgcgcgatc ggacaggccc gcgggccgtc ggacgattcc tgcatcggtg catcctatcg
    19321 atactgggta cgtatcctga atgcagccag tctaggctgc gggcatgacc acgactgagc
    19381 ccgaatccgc gcggcccgaa tccgcctcag gccacccgca cgacccggct gcctggggcg
    19441 agccgcggag caagacgatc acctggcacg acccgctgcc ggtcgccgcg gcggcggcgt
    19501 cgctgagcgg gttggagttc ctgtccgcga tgcgtgacgg gcgcattccg ccgcccccga
    19561 tctcccgcct gttcgacttc cggccggtcg aggtcgcgcc gggagacgtt gtcttcacct
    19621 gtctgccgga cgagtcggcc tacaacccga tcggcctcgt ccacggtggc ctggtctgca
    19681 cgatcctgga caccgcgact gcctgcgcgg tgcactccac gctggcggcc gcggtggcgt
    19741 atacctccat cgagatcaag gttaattacc tgcggccggt acgcgtcgtc gtcggccggc
    19801 cgagccggct caccgcgcac ggctgggtga ccaggccggg acggcgggtg gctttcgctg
    19861 agggagacgt ccgggatgac cagggcaagg tcgtggccac cgccagcagc acctgtctga
    19921 tcatgggtga gacggcctga tcccatggcc tgatcccatg gcctgattcc gcggcctggc
    19981 cggagacccg acccgacgct cggccgggcc ggatgcgacc acgggcacgt cgtcgggctg
    20041 ctggcccgac atcgtccgtg gactgtcccg aacccgtgtc cgcgctgtcc cggccttgtc
    20101 ttcccggtgt ccgcaactcg gcggggtcgg ctaacggaca cccttgtggg gcagttcatc
    20161 ggacgatcca catgcagtct gtacgtacac gctgtatggt caatgcagag atcatcgctc
    20221 atccactggt gacctaacga gagggggcca gccgtggcgg tcgagtggcg gtaccagctc
    20281 cggattggga cctacctggc gaagcagaag ctgcttcgtc gcaagcactt cccgctcgta
    20341 ctggagctgg agccgctgtt tgcctgcaac ctgtcctgca ctggatgtgg caagatccag
    20401 catccggcgt ccgtgctcaa gcagcggatg agcgtcgacg acgccttggc cgcggtggag
    20461 gaatgcggtg ctccggtggt cgcgatcgcg ggcggcgagc cgctgatgca cccgcagatc
    20521 cacgagatcg tgaaccagct ggtcaagcgc aagaagttcg tgatcctctg cacgaacggg
    20581 ctgctgctcc agaagaagct caagaacttc accccgtcgc cgtacttcac cttcgtcctg
    20641 cacatcgacg gtctgcgtga gcggcacgac gcggtggtgg agaaggaggg cacgttcgac
    20701 gagtgcgtcc gtgccttcca cgcggcgaag gccgcgggct tccgggtcgg gtccaactcg
    20761 acgttcttca acaacgacag cccgcaggac gtcatcgaca tcctgacgtt cctcaacgac
    20821 gacctcaagg tcgaccagat ccagctctca cccggctatg cctacgagaa ggcgcccgac
    20881 caggagcact tcctgggggt ccaggagacc cgcgagatgt tctcgaaggt cttcgcggac
    20941 ggccggcgca agaagttccg gctcaaccac tcgccggtct tcctggactt cctggagggt
    21001 aagagggagc tcagctgcac cgcgtggggc atcccgagct actcgctctt cggctggcag
    21061 aagccctgct acctgatgag tgacgggtac gtctcgtcct acaaggagct cgtcgagacc
    21121 accgactggg acgcctacgg tcgtggcaag gacccgcggt gcgcgaactg catggcgcac
    21181 tgcggctatg agacctccgc ggtgctggcc accatgggtt ccctcaagga gtccatccga
    21241 gcggcccgca gcgtctgagc tggctcatcg tggtctgagc cggctcacgg cgccaccgtc
    21301 accgtcaggt gacgtcgtcc ggccggcagg tcgccgcccc gaccgggttc acccggtcgg
    21361 ggcggtcgtc gtctgtgccg ccccgcctcg cgtcggcggg agcagggccg gcgggagcag
    21421 ggtttcgctg gcgttgacga cgccagccgg ccttagccgg cggtcccgcg ggagccggcg
    21481 ccgccgtcgg cactgaccgg cggctgctcg gcgagatcgc caccgcggcc gagcccgcgc
    21541 agcagccggt cgagcacggt gccgacctcg aggcgggcgg tgtccgggtc cgcggcgccg
    21601 gcggtgtaga tgctcgcctc cgacagcagg gcggcgacca gcctggtcag cgggaccact
    21661 ggcagcgggt cgatgcggtc ctcggccatc gcgcgctcca gccactccga gagcagccgg
    21721 tagccgtgct tctcaacgag cgcatcccag gcgtcgttgc ccagcacggc cggaccgtcg
    21781 acgaggacaa tgcgctggaa gtcgctgtcc gcggtggaga tgtcgagcag ggactggaac
    21841 ccggaccgga gctgcgtcca ggcgtcgctg ggaagctccg cgtcccgggc aagttcaccg
    21901 gcgacgagct gttcggccac ctccgtcgcg acctgttcca tcacggtgcg aaacagtgcg
    21961 gccttgtcgc ggaagtggtg ataaagcgcg ccgcgggtga cctgcgcgtc ggcgacgatc
    22021 tcctcggtgc cggtggaggc gaacccctgt tcggcgaacc gacggcgggc ggcggagatc
    22081 agggcctgac gggtgtcagc cgtctgctcg gtacgacggc ttcgtgtcac cccttgatta
    22141 tggtgtagcc gaggccgttg tacccactac cgtcccggca cgagcgggcc tggtcgtgac
    22201 gaagctgctc cgatgcaccc gcaaccgccg acggacgccg atccgtggct gttgcctcgc
    22261 cccctggtcg cgccctcgcc agccgttcgt cgcgcatcgc cgatcacttt tcgttttcaa
    22321 ctggttgcag ccgggtatct ccgatcaccc ctgtcgatca tgaggttacg ggaggtgctc
    22381 attgttgccg cggggcgtgg tgggcaccat cgtcgatgct catgtcggct accccgccgc
    22441 cggccggagg cctgggattt catggtggcg cggcaggaga gtttcggggg ggagatctcc
    22501 ataccggctc ggccagaccg ggacggaagc cttgtaaccc cgcattaccc ggggcgcccg
    22561 cacgcccttg aggggcccgt ggcagtatca ctttctgtga cagtgctgct gtgggtcgcc
    22621 gttgcctctc tgctcgcctg gctctacctg accgtcggcc atgggttctt ctggcggacc
    22681 gatcagcgcc tgccatcccg gcaggcgccg accgcttggc ccagtgtggc gatcgtcgtg
    22741 ccggctcggg acgaggccga cgtgcttccc gtgacgcttc cgacgctgct tgcccaggac
    22801 tatcccggtc ctgtccagct gatcctggtg gacgacggtt ccaccgacgg gaccacggag
    22861 gttgcccggg acctggcgga acaggccgcc acgcgtggtg agaccaacgt gacgccggcc
    22921 atgaccacat ccaccgaacc ccccactggc tggaccggga agctgtgggc gctgcggcgg
    22981 ggcatcgagt gcgctggcga cgtcgacttc ctgctcctca ccgacgcgga catctcccac
    23041 cgcccgggat cgctgaccgc gctcgtcgag tcggcgacct cccagaagct ggacatggtg
    23101 tcgcagatgg ccgtgctacg ggtgcagacc ggctgggagc gtctgatcgt cccggccttc
    23161 gtgcacttct tcgcgatgct gtacccgttc cggtggtcga accggccggg ttcgcgggtg
    23221 gccgccgcgg ccggcggatg ctccctgatc cgccgggagg cccttgcggc ggccggtgga
    23281 ctggcggagg tgcgcggcgc cgtcatcgac gacgtggcga tcgcgcggat catcaagcgc
    23341 tcgggcgggc ggacgtggct cggactcgcc gagcaggtcc acagccagcg cccgtatccg
    23401 cggctcgcgg atctgtggaa gatggtgtcc cgcagcgcct atgcgcagtt gcggcactcc
    23461 ccgtcgctgc tggtcgggac cgtgttggga ctgagcctgg tcttcgtcat cccagtggtc
    23521 gcgaccatcg tgggcatcgt gaccggcgac gtcgccacgg ctctcgtcgg tgggatcgct
    23581 tggttgatca tgactgtcac ctatctgccg atgacccgct actattgtca gccgctgccg
    23641 ctggccctgc tgctccccgg agtggccgtg ctgtacctcg cgatgacggt ggactcggcg
    23701 cggctcaagc gggccgggcg gggagcggcc tggaagggac gtacctacca ggatcacggt
    23761 gccccggccg ccgcccccga gtatccgaac ggcccgggtg aacggcgtga gggttcggtg
    23821 gccgggccgc ccgactccgg cggctcatcg gcctccgccg gcggctcatc ggctttgcca
    23881 tccgcctcgt ccacggtgcc cgcaacaccc ctggtaatgg cgacatcctc ggcggtcccc
    23941 gcgccggccg tggcgccggc ttcccccacg cctacgtcca taccgacgcc cactcccacg
    24001 cggtggcccg catcgtcatc ggcctcgccg ccggtccggg gcggatcgac cgatcagccc
    24061 cggacctagc cggtggtccc gagctaggac ggggtgccgt ggccgagtcg gtagagggcg
    24121 gtggctagga acgctccgtc gcgtgagtga gtcatccatc ccggccggga cagtcgaaca
    24181 ggaccggctg gcggtcggcc tcaccatccg cgacaggcag atcgtcgccc tgctgggtcg
    24241 gcctccggct tggaccgcga cagtaaccgc cgggcccgcg ccggacaggc ggtcgcgctg
    24301 ttctatcggc tctacggcac cgcacccgcg cctgactgcc cgtccgagtc agaccgtggc
    24361 aggagccggc ccttgttcca gacgacgtcg gagagtaacc gcattctcgg caagggcgga
    24421 gatgagataa cccggaccag ccaggggaag cagcgccacc ccgtccgcga cggccgcttg
    24481 cgcgccggat tccgccctct ttgccggcac ggactcccgc cgggctgccg gagagcccac
    24541 cggatcgggc cccgcgacga ggagcgaccc gagggcacga gccgagccga ggagggctgg
    24601 tccggtcagg ccaggtatct cgggaccgag gacgagatcc tggcgcagca ggggggtcgg
    24661 ttcggatggc ggatccacct ccgcatgggc gtccatgtcc acccgcaggg tgctacgtat
    24721 cgatccggtc gtctccccga atcggcccag cacgatctcc tcgcgcagcc gtagccaggc
    24781 cgtggtcgcc aagtgcacat cggtcaccag gagatggtcc gagccccgcg ccgcgacggt
    24841 cggctccggc gcgaagtcca gcgcgccacc cggggccacc cgtgccgaca cggtgaagcg
    24901 ggacggcccg ggcccgtgac cgggcagggc caccgtcgcg gccaccgaac gcaccaccag
    24961 gcgcaccccg ctgccgacgg agatgtcgag tcccagatca tcacccgcca gcggtccggc
    25021 ggtcgcgttg accaggtgaa ccgtcgcggt cggcagcgcg tccgcggata gcgcgggcac
    25081 cgtagacggg gccctggtcc gaccagggga tgctccggtc tggcgcagga cgatcggcac
    25141 gtcggagcgc aactcgatga gcctcgccgt gccgtccgga gccgattcga cccggatgac
    25201 ggcccgtgcc cgtacggccg tgcggcccgt tcgggcggcc gtgacgaggg ggccctccgg
    25261 cccggccgcg accccgccca ggatgacccc ccgtctcatg gctgccatgg tgccagccgg
    25321 gggcgacggg atcggccggc gcccgcgggt ccacccggcg ccgcgcgatc gcgatcggcc
    25381 gagtagccga ccatgcgagt agccgacggg ccgggtctgg gaccgatgac gacgagtcgg
    25441 cgggcaccgg tcaggatgtg aacatccgta gcgccgtggt gcggtgccgt tcggccagga
    25501 gatcgaggcg gataccggtg acggcgggca gcagccgggg cgggcgtcgg gaagcctccg
    25561 cgccggccag cgcgatcgcc tcgacctcgt cggtgagccg ggcgagcacg gcggtgacgg
    25621 ccaaggggtc cagccccatc aggcgggtcg cggcggtcgc gggtccggtg accgtggtgt
    25681 gggcggcgac cagggcggcg tccgagggac gcaggcccgc gcccgcggcg accatgccta
    25741 gtgcgcacgg gtggtgcggt gcacgtggac cgggcggcac gggccaggcg gcccggcccg
    25801 ctcgcagcag cgtgcgcccc tgagcccggc tcgcgtcgcg ttgggcgggg gagggcatcc
    25861 gggcgtcgag ctcggcgtcc aaggtggcga tggtggtggg tgtgacgatg gtgacgggtg
    25921 tgacggatgc ggtggggacg tggtcggcgt gtggcgcccg cgtcgcggga cccggctgcg
    25981 tgccggcccg gcaggctgcg gccgcgaagg ccgcggcgac caggccggtc gtggtgagcc
    26041 gtccgacgag gaaggccgcc aggtcggaca ggttcgccag actcccgtcc gtcaccgctg
    26101 cttcaacacc gcccgagtgg gcgtgacctc ccgtgggcat ccggccgtcc gcgaggacca
    26161 gcagcgtcgc ccgccgtccg gatcgcccgg tcggaccagc cacgtcctcg gtcccgccgt
    26221 cccgtgcggt atcgccctca atcgtcaccg tagccgctcc cggcgttagt cagtgtccga
    26281 accgctgtgg cgtttacatt catcgggccc ggaagattca tcgggcccgg aagcctctgg
    26341 atacgcagtg acagccgtgg taagaaccgt cagaacactc agaatcagaa cattcagaac
    26401 aggaagtagc gctgggtcat cgggagttcg ctcaccggat ccgcctcgat cgcctcaccg
    26461 tccaccgtga cggtgaacgt gtcggggtcc acccggatgt ccggtgtcgc ggtgttctcg
    26521 ggaagatccg ccttgccgcg gcggcgcaca tccgcgaccg gcaccaccgg ggtggcgagc
    26581 cccagccgtc cgggcagccc gtcctcgatc gccgccgggg caacgaagat caacgacgac
    26641 gcggcggccg gaccacgggc ggctccccac atcggccggg gcagcaccgg ctgcggggtc
    26701 gggatggagg cgttcgcatc gcccatcgcg gcccaggcga tgaacccgcc cttgaggacc
    26761 agcgacggcc gcaccccgaa gaacgccggg tcgtacagca ccaggtcggc gagcttgccg
    26821 ggctccaccg agccgatctc cgcgtccagg ccgtgcgcca ccgccgggca gatcgtgtac
    26881 ttggcgatgt agcgtcgggc ccgggtgttg tcggcccgat cgtcgccggc cagggacccg
    26941 cgccggagct tcatcacatg cgcggtctgc caggtacgca ggacgacctc gccgatccgg
    27001 cccatcgcct gcgagtccga accgatcatc
//
