LOCUS       NC_003155              51672 bp    DNA     linear   CON 12-JUL-2024
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893, complete sequence.
ACCESSION   NC_003155
VERSION     NC_003155.5
KEYWORDS    RefSeq.
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Ikeda,H., Kazuo,S.Y. and Omura,S.
  TITLE     Genome mining of the Streptomyces avermitilis genome and development
            of genome-minimized hosts for heterologous expression of
            biosynthetic gene clusters
  JOURNAL   J Ind Microbiol Biotechnol 41 (2), 233-250 (2014)
   PUBMED   23990133
REFERENCE   2
  AUTHORS   Ikeda,H., Ishikawa,J., Hanamoto,A., Shinose,M., Kikuchi,H.,
            Shiba,T., Sakaki,Y., Hattori,M. and Omura,S.
  TITLE     Complete genome sequence and comparative analysis of the industrial
            microorganism Streptomyces avermitilis
  JOURNAL   Nat Biotechnol 21 (5), 526-531 (2003)
   PUBMED   12692562
REFERENCE   3
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kikuchi,H., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Genome sequence of an industrial microorganism Streptomyces
            avermitilis: deducing the ability of producing secondary metabolites
  JOURNAL   Proc Natl Acad Sci U S A 98 (21), 12215-12220 (2001)
   PUBMED   11572948
REFERENCE   4  (bases 1 to 9025608)
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kushida,N., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2002) Contact:S Omura Kitasato University,
            Kitasato Institute for Life Sciences; 1-15-1 Kitasato, Sagamihara,
            Kanagawa 228-8555, Japan URL
            :http://avermitilis.ls.kitasato-u.ac.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000009765.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:55:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,040
            CDSs (total)                      :: 7,942
            Genes (coding)                    :: 7,651
            CDSs (with protein)               :: 7,651
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 293
            CDSs (without protein)            :: 291
            Pseudo Genes (ambiguous residues) :: 0 of 293
            Pseudo Genes (frameshifted)       :: 128 of 293
            Pseudo Genes (incomplete)         :: 220 of 293
            Pseudo Genes (internal stop)      :: 25 of 293
            Pseudo Genes (multiple problems)  :: 77 of 293
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:08:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8758094
            Orig. end                         :: 8809766
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BA000030.4.
            On Mar 29, 2016 this sequence version replaced NC_003155.4.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..51672
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="hglE-KS"
                     /region_number="38"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(hglE or hglD)"
                     /tool="antismash"
     cand_cluster    1..51672
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(hglE or hglD)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="hglE-KS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..44572
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..44572
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:24572](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..24572)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(476..491)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     gene            complement(510..956)
                     /db_xref="GeneID:41544413"
                     /locus_tag="SAVERM_RS37700"
                     /old_locus_tag="SAV_7343"
                     /old_locus_tag="SAVERM_7343"
     CDS             complement(510..956)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004521 - RNA endonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005484304.1"
                     /locus_tag="SAVERM_RS37700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7343"
                     /old_locus_tag="SAVERM_7343"
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_037647212.1"
                     /transl_table=11
                     /translation="MTAFTDEDIPGRHGPSATTEAEPRTVGRVRTEYSPAHDGDPDPGE
                     IVWTWVPFEENDGRGKDRPVLVVAREAAGTLLAVQLSSKRHDGDREWVPIGSGPWDRSG
                     RDSWVAVDRVLRLHESGMRREACALDRMRFNLVVHRLRERYGWR"
     misc_feature    complement(933..948)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            complement(1055..2542)
                     /db_xref="GeneID:41544414"
                     /locus_tag="SAVERM_RS37705"
                     /old_locus_tag="SAV_7344"
                     /old_locus_tag="SAVERM_7344"
     CDS             complement(1055..2542)
                     /codon_start=1
                     /db_xref="GeneID:41544414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380303.1"
                     /locus_tag="SAVERM_RS37705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7344"
                     /old_locus_tag="SAVERM_7344"
                     /product="flotillin family protein"
                     /protein_id="WP_037647117.1"
                     /transl_table=11
                     /translation="MPMIVGVVAGAAVLALIFIVVVFKLMWRVAEPNEALIISGSKHRT
                     EGLEEGMGFRIVTGRGTLVLPGVQAVRKMSLDLNETELSVDCVTTQGIPLKVRGVVIFK
                     VGDDFVSIANAGRRFLDQQKLMAERVHNVFAGHLRSIVGGLTVEDMIRDREKLTGQTRA
                     ACGTEMEKLGLIVDSLQIHEIEDPTGYIKNLAMPHAAAVQRDARIAQAEANRLATEAEQ
                     LAASRMSEATRDSEILQAGYQAERDKAAAKAKQAGPLADAAARQDVVVQETRVAELEAH
                     RREQQLQADVRKPADAKAYETRARAEADRDARISAAQAKAKETELAAAAEATRVKTAAS
                     AEAEATKARGAASATATRATGEAEAAAAQAKGLAVAEATRAKGLAEAEAIKARAAALAE
                     NQEAVVAQQLAENWPEIVQAGASAFNNVEHMVLLNGADGMGDMFAKALTMGGTGLGLAR
                     QLLASMNQNGTAGGGAAGLNGFVPARTEKVPVEKDEG"
     misc_feature    complement(2528..2543)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.15"
                     /tool="antismash"
     gene            complement(2677..2901)
                     /db_xref="GeneID:41544415"
                     /locus_tag="SAVERM_RS37710"
     CDS             complement(2677..2901)
                     /codon_start=1
                     /db_xref="GeneID:41544415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009343008.1"
                     /locus_tag="SAVERM_RS37710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_037647214.1"
                     /transl_table=11
                     /translation="MTMDDASMVGLMGRVTGTIGPGLVGEVIVRVRGGAEHFLAYPASA
                     QDRIEPGTVVMVIEYLPPRTVYVAAAYDS"
     gene            complement(2898..4403)
                     /db_xref="GeneID:41544416"
                     /locus_tag="SAVERM_RS37715"
                     /old_locus_tag="SAV_7345"
                     /old_locus_tag="SAVERM_7345"
     CDS             complement(2898..4403)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /db_xref="GeneID:41544416"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676453.1"
                     /locus_tag="SAVERM_RS37715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7345"
                     /old_locus_tag="SAVERM_7345"
                     /product="amidase"
                     /protein_id="WP_037647118.1"
                     /transl_table=11
                     /translation="MAAERADTPPERAEGLARCARALADGEVTSRELVERTLARIEATQ
                     PSLNAFRLVRAEASLAEAQAADRELAAGARRPLLGVPVAVKDDMDVAGEPTAFGCRGEF
                     PPRAEDSEAVRRLRAAGAVIVGKTNTCELGQWPFTEGPAFGATRNPWHPDHTPGGSSGG
                     SAAAVAAGLVPAALGSDGAGSVRIPASWTHLVGIKPQRGRISTWPRPESFQGITVNGTL
                     ARTVADAALLLDAASGNHAGDLHRPPATGVLEAVGREPGRLRIALSLKPPFTALPARLD
                     PRVRARVLELAERLAALGHVVEEAEPRYGRIGLTFVPRATAGLAEWVRDAPFPDLLDRR
                     TRDAARLGRLLGGAPLRLARAAEARLHRRVGALFDVYDVLLAPTTAAPPPHIGSMVNLN
                     GFGTDRAMIAACPYAWPWNVLGWPGVNVPAGFVDGGPSPAEGGRDGGLLPVGAQLLGPA
                     HSEPLLVSLAAQLEADRRWHEQWPPASTDADSAATRRSSGRTL"
     cand_cluster    4575..51672
                     /SMILES="CC(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(hglE or hglD)"
                     /kind="single"
                     /product="hglE-KS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4575..51672
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[24574:31672](-)"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(24575..31672)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
     gene            4593..5639
                     /db_xref="GeneID:41544417"
                     /locus_tag="SAVERM_RS37720"
                     /old_locus_tag="SAV_7346"
                     /old_locus_tag="SAVERM_7346"
     CDS             4593..5639
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544417"
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995885.1"
                     /locus_tag="SAVERM_RS37720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7346"
                     /old_locus_tag="SAVERM_7346"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_171033146.1"
                     /transl_table=11
                     /translation="MPYVMVHIPNEPVPSPSAPRSVPTSADVARLAGVSRATVSYVLNN
                     TSAVRISEPTRRRVHEAAKELGYVPHAAARSLRAGHSRMVLIPTPNVPVGPLYNQFFNE
                     LQWALSRLEYTVVQYGDLSPHGDEAARAWAELRPVAVLVPGGGLGPQGLAVLKRSGARA
                     VVTLGAERVEGAHAVLLDHEGVGHSAGRHLLARGRRAVGVVVPEEPGLEMFSKPRLEGV
                     RRALQGTGATVTELPLAYEEEAAARLAARWRPLGLDAVFAYNDEYAMLLMRALQDEGIA
                     IPRETAVIGADDLMLGRLLRPRLSTVHIELPSGRDLAELVDRAVRDPGVAPEVHEVLGT
                     RVVQRESS"
     gene            complement(5825..6214)
                     /db_xref="GeneID:41544418"
                     /gene="trxA"
                     /locus_tag="SAVERM_RS37725"
                     /old_locus_tag="SAV_7347"
                     /old_locus_tag="SAVERM_7347"
     CDS             complement(5825..6214)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544418"
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995881.1"
                     /locus_tag="SAVERM_RS37725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7347"
                     /old_locus_tag="SAVERM_7347"
                     /product="thioredoxin"
                     /protein_id="WP_010988742.1"
                     /transl_table=11
                     /translation="MSSTVELTKENFDQTVTDNEFVLIDFWASWCGPCRQFAPVYEKAA
                     EANPDLVFAKVDTEAQPELAAAFDIQSIPTLMIVRDQVAVFAQPGALPEAALEDVIGQA
                     RKLDMDEVRKAVAAQQAQAQAQQGE"
     misc_feature    6165..6180
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            6343..7776
                     /db_xref="GeneID:41544419"
                     /locus_tag="SAVERM_RS37730"
                     /old_locus_tag="SAV_7348"
                     /old_locus_tag="SAVERM_7348"
     CDS             6343..7776
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /db_xref="GeneID:41544419"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043748.1"
                     /locus_tag="SAVERM_RS37730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7348"
                     /old_locus_tag="SAVERM_7348"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_010988743.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.3e-47, bitscore:
                     159.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETESIAYDVVVLGAGPVGENVADRTRAAGLSTAVVESELVGGE
                     CSYWACMPSKALLRPVIARADARRVPGVSHLAQGHLDTAAVLAHRDYEVSHWKDDGQVG
                     WLDGIGADLYRGHGRLSGPREVTVTGPDGDRRVLTARHAVAVCTGSRALLPDLPGLDQV
                     EPWTSREATSAQAAPGRLIVVGGGVVAVEMATAWRALGSEVTVLVRGKGLLPRMEPFAG
                     ELVAEALKEAGADVRTGTSVSAVTREGPTVVVLTDTGDRIEADEILFATGRAPRTDDLG
                     LDTVGLEPGSWLSVDDSLRVTGSDWLYAVGDVNHRALLTHQGKYQARIAGAAIAARASG
                     VPLLESDPWGAHAATADHAAVPQVVFTDPEAAAVGLSLAEAERAGHHVRAVDVEFSSVA
                     GAGLYADGYRGRARMVVDVNRETLLGVTFVGPGVGELIHSATIAVAGEVPIGRLWHAVP
                     SYPTISEVWLRLLEAYRDA"
     gene            complement(8093..8767)
                     /db_xref="GeneID:41544420"
                     /locus_tag="SAVERM_RS37735"
                     /old_locus_tag="SAV_7349"
                     /old_locus_tag="SAVERM_7349"
     CDS             complement(8093..8767)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0018206 - peptidyl-methionine modification
                     [Evidence IEA]"
                     /GO_process="GO:0031365 - N-terminal protein amino acid
                     modification [Evidence IEA]"
                     /GO_process="GO:0043686 - co-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544420"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988744.1"
                     /locus_tag="SAVERM_RS37735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7349"
                     /old_locus_tag="SAVERM_7349"
                     /product="peptide deformylase"
                     /protein_id="WP_010988744.1"
                     /transl_table=11
                     /translation="MASESDRTVPDTRSASRPLADRVEELLATGGPLPIVAAGDPVLRR
                     GAEPYDGQLGPGLLARFVEALRLTMHAAPGVGLAAPQVGVGLRIAVIEDPAPVPEEVGA
                     VRGRVPQPFRVLVNPSYEAVGSDRAAFFEGCLSVPGWQAVVARPARVRLTALDEHGRAV
                     DEEFTGWPARIVQHETDHLDGMLYLDRAELRSLSSNEAMALRWSQPTPERAAAALGFAL
                     PD"
     gene            8963..10375
                     /db_xref="GeneID:41544421"
                     /locus_tag="SAVERM_RS37740"
                     /old_locus_tag="SAV_7350"
                     /old_locus_tag="SAVERM_7350"
     CDS             8963..10375
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068406.1"
                     /locus_tag="SAVERM_RS37740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7350"
                     /old_locus_tag="SAVERM_7350"
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="WP_010988745.1"
                     /transl_table=11
                     /translation="MTTAPSAPDAPSTTTDEPPQSGTPGPARWAPLRPLVLRLHFYAGL
                     LVAPFLLVAALTGFLYAASYQAEKIVYAHELTVPVGDTELPISQQVAAARKAHPEGTLT
                     AVRPSPEADATTRVLLSGVKGVDEGHTLAVFVDPYTGKVRGSLEQYGSTGALPLRTWID
                     EFHRDLQLGENGRLYSELAASWLWVIAGGGLVLWFGRRRAQRKVRGTSGRRRTLGLHGT
                     VGVWAAAGFFFLSATGLTWSTYAGANIDELRTSLGQATPSVSAAAAGEHAGHDAAAGTG
                     GTEHGVGLDKILAAARAKGLGDPVEIVPPADASSTYVVKQVQRSWPEKQDSVAVDPATG
                     EVTDTLRFADYPLLAKLTRWGIDAHTGVLFGLVNQIALMALALSLVLLIVWGYRMWWQR
                     GRASAFGRPIPRGAWQQVPPQILVPCMAVIAVLGYFVPLLGIPLAVFIAVDVVLGEIAH
                     RRGQRTYGRQVA"
     misc_feature    10393..10407
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            10407..10820
                     /db_xref="GeneID:41544422"
                     /locus_tag="SAVERM_RS37745"
                     /old_locus_tag="SAV_7351"
                     /old_locus_tag="SAVERM_7351"
     CDS             10407..10820
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568078.1"
                     /locus_tag="SAVERM_RS37745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7351"
                     /old_locus_tag="SAVERM_7351"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_010988746.1"
                     /transl_table=11
                     /translation="MAQREANSPHRGSRRRGQGELEVQVLGALREADGPVTASWVQEHL
                     GGDLAYTTVVTILTRLLAKDVVSRERQGRSFAWTPTADVARLAALKMRRLLDGERDREA
                     VLASFVTALPPDDEQVLRTLLDAADTADGGTEG"
     gene            complement(11104..11451)
                     /db_xref="GeneID:41544423"
                     /locus_tag="SAVERM_RS37750"
                     /old_locus_tag="SAV_7352"
                     /old_locus_tag="SAVERM_7352"
     CDS             complement(11104..11451)
                     /codon_start=1
                     /db_xref="GeneID:41544423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387319.1"
                     /locus_tag="SAVERM_RS37750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7352"
                     /old_locus_tag="SAVERM_7352"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_010988747.1"
                     /transl_table=11
                     /translation="METTYYDQGTAAERWERAQMFFDAKDYAVAARILDGLVDEVPEQT
                     GPRLLLARSYYHSAQLGRAEAELRILVERDPVEHYARLMLGRTLQRQGRDDEADSQLRI
                     ASALAGDFEAR"
     misc_feature    complement(11485..11498)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.06"
                     /tool="antismash"
     gene            complement(11529..11993)
                     /db_xref="GeneID:41544424"
                     /locus_tag="SAVERM_RS37755"
                     /old_locus_tag="SAV_7353"
                     /old_locus_tag="SAVERM_7353"
     CDS             complement(11529..11993)
                     /codon_start=1
                     /db_xref="GeneID:41544424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655958.1"
                     /locus_tag="SAVERM_RS37755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7353"
                     /old_locus_tag="SAVERM_7353"
                     /product="winged helix DNA-binding protein"
                     /protein_id="WP_010988748.1"
                     /transl_table=11
                     /translation="MTTTNPTTNLTTNPTVNGQVIGLAHYAGRGLLETVLARTGTTFEE
                     SVALHAAAAAGGTVARDRLVDRLTGALKTGETPARQAVDELIAAKLLDEPAPGQVSLTD
                     SGRELFESIQAGGKEIATRLYAGIPAQDLETAGRVLTLVTERANAELAAL"
     gene            complement(11990..12517)
                     /db_xref="GeneID:41544425"
                     /locus_tag="SAVERM_RS37760"
                     /old_locus_tag="SAV_7354"
                     /old_locus_tag="SAVERM_7354"
     CDS             complement(11990..12517)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544425"
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127596.1"
                     /locus_tag="SAVERM_RS37760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7354"
                     /old_locus_tag="SAVERM_7354"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_010988749.1"
                     /transl_table=11
                     /translation="MSNTVSDTAPEGATPGFLVWRLSMKWRVAVDRAVAPLGLTHAQYS
                     LVATLVGMHRTGLRPNQRQLADHTGLEALYVSKLARALESGGLVDRTRDPADPRAIQLS
                     LTPRGHEVAQQAIKVVHRLLEQLLQPLGGLDSPRTTRFTHELRTLLDAPLDASIEPGTS
                     TELGTPAAEEQS"
     misc_feature    complement(12520..12538)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.31"
                     /tool="antismash"
     misc_feature    12524..12542
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.77"
                     /tool="antismash"
     misc_feature    complement(12525..12543)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    complement(12538..12558)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.28"
                     /tool="antismash"
     misc_feature    complement(12654..12668)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.57"
                     /tool="antismash"
     gene            12662..13627
                     /db_xref="GeneID:41544426"
                     /locus_tag="SAVERM_RS37765"
                     /old_locus_tag="SAV_7355"
                     /old_locus_tag="SAVERM_7355"
     CDS             12662..13627
                     /codon_start=1
                     /db_xref="GeneID:41544426"
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068410.1"
                     /locus_tag="SAVERM_RS37765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7355"
                     /old_locus_tag="SAVERM_7355"
                     /product="pirin family protein"
                     /protein_id="WP_010988750.1"
                     /transl_table=11
                     /translation="MSNLDREAVPTLCGGRGFVVAEPVRELLSPRKVKLGESTEVRRLL
                     PNLGRRMVGAWCFVDHYGPDDIADEPGMQVPPHPHMGLQTVSWLHEGEVLHRDSTGSLQ
                     TIRPRELGLMTSGRAISHSEESPKSHARFLHGAQLWVALPDSHRHTDPRFEHHAELPVV
                     TAPGLQATLILGEVDGATSPGTTFTPIVGADLSLASGADVRLPLEPDFEYAVLSMSGEA
                     HVDGVPVLPGSMLYLGCGRSELPLRAESDAGLMLLGGEPFEEELVMWWNFIGRSNEDIA
                     QARSDWMAGSRFGEVVGYDGAPLRAPELPPVPLKPRGRVR"
     gene            complement(14306..14710)
                     /db_xref="GeneID:41544427"
                     /locus_tag="SAVERM_RS37770"
     CDS             complement(14306..14710)
                     /codon_start=1
                     /db_xref="GeneID:41544427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048531.1"
                     /locus_tag="SAVERM_RS37770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_037647119.1"
                     /transl_table=11
                     /translation="MSARNRRLPRHRAWPLTTTDINERLGPYMTRVTDLQFLTGHDSGT
                     IVLGAEWVAPNPRNYGRGIHPDMVGFRIDVHPVDATERAATRAVLRAHALPQLHEWITQ
                     VIAADETWQLTPHQHYWRLTDGHLTHHDEA"
     gene            complement(14813..15082)
                     /db_xref="GeneID:91294882"
                     /locus_tag="SAVERM_RS45125"
     CDS             complement(14813..15082)
                     /codon_start=1
                     /db_xref="GeneID:91294882"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAVERM_RS45125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_037647121.1"
                     /transl_table=11
                     /translation="MDPWFGNTTIASTLNHQALGYIYDTERPAAQGDRMLPGDMLVADQ
                     YLVSQNGSYTFTYQKDGNLVLYRNDGSTSSTTATRASAVRTAHS"
     gene            complement(15915..17678)
                     /db_xref="GeneID:41544428"
                     /locus_tag="SAVERM_RS37780"
                     /old_locus_tag="SAV_7357"
                     /old_locus_tag="SAVERM_7357"
     CDS             complement(15915..17678)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544428"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063175.1"
                     /locus_tag="SAVERM_RS37780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7357"
                     /old_locus_tag="SAVERM_7357"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010988752.1"
                     /transl_table=11
                     /translation="MTDDPTPTTPPGSLSALIGYARPHWRVLLLSLVLTLLASVSGLVQ
                     PKFAQAILDRLDDGAGVVAPVALLAVFLVAGALLTGLNAWLQQRTSERVVRQVRRGLVH
                     RLIRLRVAELDRRAPGDLIARVTSDSTLLKSAATEGLIMTVNGVLTFAGALFMMAALDA
                     RLLGVTLLVLTLVGVVITVILPRIKAAVARSQSSVGAVGAVLDRTLGAARTVKANGAEG
                     RETLAAEDAVDEAYAAGLVGARYSALVTMVGGAAIQTAFLVVLGVGGTFVANRTMSVSE
                     LIAFLLYVFFLASPVSQLVGGAAQLQQGLGAVGRIQEAAGLPVEDDIDAPPAAAPAHAA
                     PPAVELTGVEFAYPGRAPALRGVGFTVPGGTQTALVGLSGAGKTTLFSLLQRFYEPTAG
                     TIRIGGQDISALPRAEVRRRIAYVEQDSPVMAGSLRENLLYAAPSATPEELAEALAVTR
                     LDALVARLPQGLDTPVGPRGVTLSGGERQRLAIARALLRRPQVLLLDEATAQLDARNEQ
                     ALSELVARAAGRCTVLLIAHRLSTVTDADQIVVLEHGGVRAVGTHHSLVDDDDLYRELA
                     ATQLLAAEPPA"
     gene            complement(17675..18868)
                     /db_xref="GeneID:41544429"
                     /locus_tag="SAVERM_RS37785"
                     /old_locus_tag="SAV_7358"
                     /old_locus_tag="SAVERM_7358"
     CDS             complement(17675..18868)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544429"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062830.1"
                     /locus_tag="SAVERM_RS37785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7358"
                     /old_locus_tag="SAVERM_7358"
                     /product="glycosyltransferase"
                     /protein_id="WP_010988753.1"
                     /sec_met_domain="MGT (E-value: 2.4e-44, bitscore: 151.0,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRFLFVVPPLVGHVNPAVGTAAALAARGHDIAWAGHPELVRGLA
                     GADAVVFPCALPEDGLSRPAGLKGPAAFQFLWESFLVPLADAMAPGVRAAIEAYDPDVV
                     VCDQQAVAGALVAESLGRPWVTSATTSAELVDPLAGMPKVAAWLDGLLGELRRRITGGA
                     GAADPRFSPHGVLAYTTRALLGPVELPDRVWLVGPSVAARPAGPDDFPWEWLEASALPT
                     VLVSLGTANNDAGARFLNAAAEALGGIADRVRAVLVDPGGVVEHPVPDTVLVRRYVPQL
                     ALLERLDAVVCHAGHNTVCEALWHGVPLVVAPIRDDQPIVAAQVVDAGAGVRLRFGRAD
                     AARIGAAVEAVLDPAQGHRKAAEAVGESFRAAGGSESAADRLETLTAESAVPGVRGS"
     gene            complement(18869..19672)
                     /db_xref="GeneID:41544430"
                     /locus_tag="SAVERM_RS37790"
                     /old_locus_tag="SAV_7359"
                     /old_locus_tag="SAVERM_7359"
     CDS             complement(18869..19672)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-128). E-value:
                     1.8e-30. Score: 98.3. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37790_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:41544430"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="SAVERM_RS37790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7359"
                     /old_locus_tag="SAVERM_7359"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_010988754.1"
                     /sec_met_domain="PF00561 (E-value: 6.5e-27, bitscore: 93.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-24, bitscore:
                     86.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 8.3e-08, bitscore:
                     31.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLRVNGIDVHVQRMGGPGDVPRPVVVLIHGMLIDSLASYYFSL
                     APQLAEDGMDVVMYDLRGHGKTSRPPTGYRMEDFVRDLDALLDALAVNRPVHLVGNSFG
                     GAIAYAMAAAHPERVASVIAIEAEPPGRAWAQSMYEGLVGEEGGLVVREVKEWLRENPG
                     ERNARPFRAAGRVLDETALAQEIPLSSLLDDDLSAIRCPVFAVFGGASKLAAQTGMLEA
                     SLARCRTVVLPGLGHSVLVEATKETYALVRDWLLGQEALALREAR"
     aSDomain        complement(19289..19600)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37790_Abhydrolase_1.1"
                     /evalue="1.80E-30"
                     /label="SAVERM_RS37790_Abhydrolase_1.1"
                     /locus_tag="SAVERM_RS37790"
                     /protein_end="128"
                     /protein_start="24"
                     /score="98.3"
                     /tool="antismash"
                     /translation="PVVVLIHGMLIDSLASYYFSLAPQLAEDGMDVVMYDLRGHGKTSR
                     PPTGYRMEDFVRDLDALLDALAVNRPVHLVGNSFGGAIAYAMAAAHPERVASVIAIEAE
                     "
     CDS_motif       complement(19334..19393)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37790_0001"
                     /evalue="1.30E-08"
                     /label="NRPS-te1"
                     /locus_tag="SAVERM_RS37790"
                     /protein_end="113"
                     /protein_start="93"
                     /score="27.3"
                     /tool="antismash"
                     /translation="RPVHLVGNSFGGAIAYAMAA"
     gene            complement(19675..20004)
                     /db_xref="GeneID:41544431"
                     /locus_tag="SAVERM_RS37795"
                     /old_locus_tag="SAV_7360"
                     /old_locus_tag="SAVERM_7360"
     CDS             complement(19675..20004)
                     /NRPS_PKS="Domain: PP-binding (24-89). E-value: 1.8e-13.
                     Score: 42.6. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37795_PP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:41544431"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059253.1"
                     /locus_tag="SAVERM_RS37795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7360"
                     /old_locus_tag="SAVERM_7360"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_037647123.1"
                     /sec_met_domain="PP-binding (E-value: 1.6e-11, bitscore:
                     43.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTELEGPAPRSAPDEATVLADLSAILRTVLEEYGLDDSEITLDT
                     SFHDDLELESIDLVTLSAQLREFYGERVNFAAFMADRGLEEIIALTVGDLVGYVVGSLA
                     VAEVG"
     aSDomain        complement(19738..19932)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37795_PP-binding.1"
                     /evalue="1.80E-13"
                     /label="SAVERM_RS37795_PP-binding.1"
                     /locus_tag="SAVERM_RS37795"
                     /protein_end="89"
                     /protein_start="24"
                     /score="42.6"
                     /tool="antismash"
                     /translation="AILRTVLEEYGLDDSEITLDTSFHDDLELESIDLVTLSAQLREFY
                     GERVNFAAFMADRGLEEIIA"
     aSModule        complement(19738..24545)
                     /complete
                     /domains="nrpspksdomains_SAVERM_RS37800_PKS_KS.1"
                     /domains="nrpspksdomains_SAVERM_RS37800_PKS_AT.1"
                     /domains="nrpspksdomains_SAVERM_RS37800_ACPS.1"
                     /domains="nrpspksdomains_SAVERM_RS37795_PP-binding.1"
                     /locus_tags="SAVERM_RS37795"
                     /locus_tags="SAVERM_RS37800"
                     /monomer_pairings="mal -> mal"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     gene            complement(20001..24572)
                     /db_xref="GeneID:41544432"
                     /locus_tag="SAVERM_RS37800"
                     /old_locus_tag="SAV_7361"
                     /old_locus_tag="SAVERM_7361"
     CDS             complement(20001..24572)
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (9-476). E-value:
                     4.1e-116. Score: 380.3. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37800_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (628-837). E-value: 1.5e-30.
                     Score: 98.5. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37800_PKS_AT.1"
                     /NRPS_PKS="Domain: ACPS (1402-1467). E-value: 1.6e-09.
                     Score: 29.6. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37800_ACPS.1"
                     /codon_start=1
                     /db_xref="GeneID:41544432"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173580.1"
                     /locus_tag="SAVERM_RS37800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7361"
                     /old_locus_tag="SAVERM_7361"
                     /product="type I polyketide synthase"
                     /protein_id="WP_010988756.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.1e-65, bitscore:
                     218.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 5.4e-114, bitscore:
                     380.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-28, bitscore: 98.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPGRAEPIAIVGMSVLFPGAPDLATYWHNLVSGVDAITDVPPG
                     RWDADEHYAPGAEPRADRVYCRRGGFVDELAEVDVTEFGIMPAAVPATEPDQLIALRVA
                     AQALADAGGADRLPADRHRVGVVLGRGGYLTPGLVRLDQRVRTASQLVRTLGELLPDLG
                     ADRLEAVRQAFTDRLGPEAPESSIGLVPNLAASRLAGRLDLRGPAYTVDAACASSLIAV
                     DHAVRELADGRCDVMLAGGVHHCHDITFWSVFSQLGALSPSERIRPFHKGADGVLIGEG
                     TGVVVLKRLADAERAGDRIYAAITGTGVASDGRTTSLMAPDSGGQVRAVRQAWQAAGLD
                     PAAPGSIGLLEAHGTATPAGDGAELATLAEVFGPPPKDATADEPGAVIGSVKSMIGHTM
                     PAAGIAGLIKAALAVHHGVLPPTLHCDEPHPALARTRFAPISAARPWPADDRQPVRRAA
                     VNAFGFGGINAHVVLEQVAVTRAAQVYEPERVLRLTAPTPEAMAALLDRDDSAILAAGL
                     DERAPAPAADPVRLAVVGPTAKRLALARKAVAKGDGWRGRGDVWFVPSPLLGPGGGKLA
                     FVFPGLEAEFVPNSEDVARHFGLPWSRAVADATVGDVGRQGTGVFELGRLLDAALRRLG
                     VAPDALAGHSLGEWTAMAAAEIHAPDEVDAFLAGFDPDALSVPGLAFAAIGAPAEQVLT
                     ELAGRTDVVLSHDNAPNQSMICGPEPAVAALVDVFRSRALISQILPFRSGFHTPMLEPY
                     LGPIRKAAETYTLHPAALPLWSATTVAPYPEEPAAIRDLFVRHLLEPVRFRPLVDTMYA
                     AGFRAFVQLGAGHLGSLIGDTLHGRAHLVVAAHSPNRSGLPQLHRVASALWADGAASDL
                     SPLLGRAAAAPARTGRRPVRLDLGGANVSLDAETRHRVSAALAPRRAPATPPPRDVGDH
                     GDHGTLGEQGLLGAELSALLRDATALASDVVSAGRRRPGAAAATHHTRATPGSRTTAVP
                     GPRTTEPPAPRPLDTTLHVSVDTMPYLLDHCFFKQPDRADPADSWPVVPGTTVIAHLMD
                     FAERAAPGRRAVAVHDVRLHQWVTATPAVDIPVRIVPESPDRVTASLGSYAQAVVELAA
                     DQGRSAPATPWAFPAPAEPWTFPAAAEEKPELTAAELYSRRWMFHGPRFQGVRELTAVG
                     ERHVRGVLVCPPAPGALLDNVGQLLGYWIMSRLPVRTTVFPVGMKEIRFHGPHPAPGER
                     LECLIRITSVTDATLEADMQLVYRGRVWAEFTGWQDRRFDSNPRIRAVDREPERHTLSR
                     MQPGGWALVHEEWPDLATRELIMRNILAGEERERYAAHAPRGRRQWLLGRIAVKDAVRH
                     LMWDGGAGPVFPAEVRVGNDPTGRPFVTGGYGRTLPALHVSIAHRGESAVAMARTEGPC
                     GIDIEEVTDRPEGTLAVALAPPERELLRALAQAPRGAPERLWFTRFWAAKEAVAKARGT
                     GLGGAPKQFEITAADGAVVSVRVAGEEYRVRHSSLTIPRPSGQPGKEYVVAWTAVNDSG
                     ERR"
     aSDomain        complement(20172..20366)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37800_ACPS.1"
                     /evalue="1.60E-09"
                     /label="SAVERM_RS37800_ACPS.1"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="1467"
                     /protein_start="1402"
                     /score="29.6"
                     /tool="antismash"
                     /translation="GIDIEEVTDRPEGTLAVALAPPERELLRALAQAPRGAPERLWFTR
                     FWAAKEAVAKARGTGLGGAP"
     aSDomain        complement(22062..22688)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37800_PKS_AT.1"
                     /evalue="1.50E-30"
                     /label="SAVERM_RS37800_PKS_AT.1"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="837"
                     /protein_start="628"
                     /score="98.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="AALRRLGVAPDALAGHSLGEWTAMAAAEIHAPDEVDAFLAGFDPD
                     ALSVPGLAFAAIGAPAEQVLTELAGRTDVVLSHDNAPNQSMICGPEPAVAALVDVFRSR
                     ALISQILPFRSGFHTPMLEPYLGPIRKAAETYTLHPAALPLWSATTVAPYPEEPAAIRD
                     LFVRHLLEPVRFRPLVDTMYAAGFRAFVQLGAGHLGSLIGDTLHGR"
     CDS_motif       complement(22596..22670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37800_0003"
                     /evalue="1.70E-08"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="659"
                     /protein_start="634"
                     /score="26.4"
                     /tool="antismash"
                     /translation="GVAPDALAGHSLGEWTAMAAAEIHA"
     aSDomain        complement(23145..24545)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37800_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="4.10E-116"
                     /label="SAVERM_RS37800_PKS_KS.1"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="476"
                     /protein_start="9"
                     /score="380.3"
                     /tool="antismash"
                     /translation="IAIVGMSVLFPGAPDLATYWHNLVSGVDAITDVPPGRWDADEHYA
                     PGAEPRADRVYCRRGGFVDELAEVDVTEFGIMPAAVPATEPDQLIALRVAAQALADAGG
                     ADRLPADRHRVGVVLGRGGYLTPGLVRLDQRVRTASQLVRTLGELLPDLGADRLEAVRQ
                     AFTDRLGPEAPESSIGLVPNLAASRLAGRLDLRGPAYTVDAACASSLIAVDHAVRELAD
                     GRCDVMLAGGVHHCHDITFWSVFSQLGALSPSERIRPFHKGADGVLIGEGTGVVVLKRL
                     ADAERAGDRIYAAITGTGVASDGRTTSLMAPDSGGQVRAVRQAWQAAGLDPAAPGSIGL
                     LEAHGTATPAGDGAELATLAEVFGPPPKDATADEPGAVIGSVKSMIGHTMPAAGIAGLI
                     KAALAVHHGVLPPTLHCDEPHPALARTRFAPISAARPWPADDRQPVRRAAVNAFGFGGI
                     NAHVVLEQV"
     CDS_motif       complement(23346..23423)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37800_0002"
                     /evalue="1.10E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="409"
                     /protein_start="383"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="PGAVIGSVKSMIGHTMPAAGIAGLIK"
     CDS_motif       complement(23910..23957)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37800_0001"
                     /evalue="3.30E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="SAVERM_RS37800"
                     /protein_end="221"
                     /protein_start="205"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GPAYTVDAACASSLIA"
     gene            complement(24575..31672)
                     /db_xref="GeneID:41544433"
                     /locus_tag="SAVERM_RS37805"
                     /old_locus_tag="SAV_7362"
                     /old_locus_tag="SAVERM_7362"
     CDS             complement(24575..31672)
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (654-1093). E-value:
                     1.2e-127. Score: 418.3. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37805_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1208-1501). E-value: 7.4e-62.
                     Score: 201.3. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37805_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1680-1746). E-value:
                     2.9e-08. Score: 25.9. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37805_PP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (1786-1855). E-value:
                     1.8e-08. Score: 26.5. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37805_PP-binding.2"
                     /NRPS_PKS="Domain: PKS_KR (2086-2309). E-value: 1.1e-39.
                     Score: 128.2. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37805_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:41544433"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059255.1"
                     /locus_tag="SAVERM_RS37805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7362"
                     /old_locus_tag="SAVERM_7362"
                     /product="type I polyketide synthase"
                     /protein_id="WP_010988757.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.6e-69, bitscore:
                     232.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hglE (E-value: 3.6e-132, bitscore: 439.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.6e-60, bitscore: 201.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-06, bitscore:
                     26.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVSNFDTSGLFAVEDIVIAVSPLAVPSARVTAAAVRAGGLGVLD
                     LTSGGRRAAAELALAEEWSAAGFGVRLSDNDAFPARDLPARVHTVLLTSDASCTPGDFP
                     GHRVLVEVTGHEQALRALSAGAHGLIARGHEAGGPVGELGTFVLVQQLLADRELDLPVW
                     ACGGAGPHTAAAVVAGGGAGVVLDTQLALLTEAEAGLPAGTSVLLTGLDGSETTVENGR
                     RVVRRRGAPDGAPAPEIGQDGFLAARFHERWGTVHAAVRGVRDAVLDALKSAGPALGPD
                     SAGSRALGTELPVVQGPMTRVSDQAAFAAEVSGHGALPFIALALSGAEQTRTVLERTRD
                     ALGHAPWGVGVLGFADEEIKAAQLEVVREIRPSHAIIAGGRPAQAAALEAVGISTFLHV
                     PSPGLLKQFLEAGARKFVFEGAECGGHVGPRGSFPLWEAQLCVLDDFLAGAKNGTAAEL
                     QLLFAGGVHDERSAAMVTALAAPLSARGAAVGVLMGTAYLFTEEAVSAGAVLPLFQRQV
                     IAAERTDLLETAPGHATRCVRSPFTDEFAAVKEELAARDVPGREAWERLEQLNVGRLRL
                     ASKGLERAGGELHEVGEERQLAEGMFMAGEVAVLRSAITTVADLHASVTTGAAGFLAAR
                     LDALGIEEPAIAASPEPLDIAVVGMACMFPGAPDLAAFWANVLAGADAVTEVPATRWDA
                     DLYHDLNGAGEKTPSRWGGFLPEIPFEPLRYGIPPASLPAIEPVQLLALEAARRALEDS
                     GYGSRSFDRARASVVFGAEAGSDLSNAMTLRSVLPAYLGTLPPALAEQLPRLTEDSFPG
                     ILANVIAGRIANRLDLGGANYTVDAACASSLTAVDVACKELSGGTSDLVLCGGADLHNG
                     INDYLLFASAHALSPSGRSAPFDSAADGIALGEGVGCVVLKRLADAERDGDRIYAVIKG
                     VGSASDGRALGLTAPRPEGQYNALTRAYRNAGVSPAEVGLVEAHGTGTVVGDRTELGSL
                     TRVFEEAGAEPGRCALGSVKSQIGHTKCAAGLAGLIKASLALHTGVKPPTLHLAEPNPA
                     WDAQSSPFAFHTEARPWPAAPAERVAGVSAFGFGGTNFHVVLRAYEDGPPPVTAAQQWP
                     AELFTFRGADRAAAVRAATELLALVEADPGPHEPWRLRDFALGASRRAESAGTRGARTW
                     IALVAESAEELAALLRRAVAGEHAPKEGLFTADDTETGEVALLFPGQGSQRPGMFAELF
                     VAFPELQRHLRLDETTARVLFPPTAFDEASRKEQQERITDTTVAQPALGLTGLAAFQLL
                     TRAGIRPAMAAGHSYGELAALAAAGALTPDALVRTSRGRAAAVLGAAGDGDPGTMAAVA
                     AGEPEVAAALAAAGLDGSVVTANRNSPRQTVISGPTDDVLTAVERLRAQGLGAKRIPVA
                     CAFHSPLVAAAGEAFAKVLADVPVGATDFPVWSNRTAARYPESPEAIRAELAAQIGAPV
                     RFADQIEAMYEAGARVFVEAGPGSVLTRLVGTVLGDRPHRTVALEKGRHTGLVGFLAAL
                     AQLAVAGVDVRTSWLFQGRGAVDAARAPRRVRAAWTVDGHLIRTADGAIPAAALHPAER
                     VPEALVTHSTSAGPVAATGSEALISEFLRTSREMIAAQRDVMLGYLGADPAVRPPAPAA
                     APATYADAPVTYADAPVTVTAPPAAPAAVAAVAEPAGGSVLSVVLDVIGERTGYPVDMI
                     EPDLDLEADLSVDSIKRAEIAGELAARLGLTTTADTDVEELAKARTAAAITALVERVTG
                     PGAVPTPAPAAQAPAPAAGPAPTAESVLALVLDVIGERTGYPVDMIEPDLDLEADLSVD
                     SIKRAEIAGELAARLGLTTTADTDVEELAKARTAASIAELVAGARGEAAEARAPEVTPA
                     ATPQSAPAGAEPLVVAPKRLVMREFDLAPAEPAPTGDRLTGRNFLLLGTGPVADALTAR
                     LTAHGAHALTADEPPADEKFDGLIHLVAPDAPPVLPDTFPVYRQVLAGNPRWVLASGTS
                     AGLRGFFRSVAREYPDTVARVVEHAPGTAPEDIAAGLVAELTADDREPVVLRSPGTRRG
                     LRMAEEGLGLLGGTGAGPAGDGAAEAAALGLDTDSVVLLVGGARGITARFAATLAAACR
                     CRIELFGRTALPEGAEDPALAPAVTTGELRAALIAGGLRVPAEIERAIGRIQAEREVRG
                     TLRRLAALGSEVRYRTVDALDGDAVRRAVKEIHAEHGRLDAVVYAAGVIEDKLIAEKSP
                     RSYDRVFRTKADGARELLDAISELPDGPRFAVLFGSIAATLGNRGQSDYAAANDALETL
                     GTRWADAGAGRRGLTVHWGPWAPTGDGNHGMVTPELMRHYAARGIRLIDPDEGTMSLLR
                     ELAWGPEGDTAVVYTASGW"
     aSDomain        complement(24746..25414)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37805_PKS_KR.1"
                     /evalue="1.10E-39"
                     /label="SAVERM_RS37805_PKS_KR.1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="2309"
                     /protein_start="2086"
                     /score="128.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VVLLVGGARGITARFAATLAAACRCRIELFGRTALPEGAEDPALA
                     PAVTTGELRAALIAGGLRVPAEIERAIGRIQAEREVRGTLRRLAALGSEVRYRTVDALD
                     GDAVRRAVKEIHAEHGRLDAVVYAAGVIEDKLIAEKSPRSYDRVFRTKADGARELLDAI
                     SELPDGPRFAVLFGSIAATLGNRGQSDYAAANDALETLGTRWADAGAGRRGLTVHWGPW
                     A"
     CDS_motif       complement(24809..24904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0008"
                     /evalue="9.40E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="2288"
                     /protein_start="2256"
                     /score="43.9"
                     /tool="antismash"
                     /translation="RFAVLFGSIAATLGNRGQSDYAAANDALETLG"
     CDS_motif       complement(25319..25414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0007"
                     /evalue="3.70E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="2118"
                     /protein_start="2086"
                     /score="6.8"
                     /tool="antismash"
                     /translation="VVLLVGGARGITARFAATLAAACRCRIELFGR"
     aSDomain        complement(26108..26314)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37805_PP-binding.2"
                     /evalue="1.80E-08"
                     /label="SAVERM_RS37805_PP-binding.2"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1855"
                     /protein_start="1786"
                     /score="26.5"
                     /tool="antismash"
                     /translation="VLDVIGERTGYPVDMIEPDLDLEADLSVDSIKRAEIAGELAARLG
                     LTTTADTDVEELAKARTAASIAEL"
     aSDomain        complement(26435..26632)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37805_PP-binding.1"
                     /evalue="2.90E-08"
                     /label="SAVERM_RS37805_PP-binding.1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1746"
                     /protein_start="1680"
                     /score="25.9"
                     /tool="antismash"
                     /translation="VVLDVIGERTGYPVDMIEPDLDLEADLSVDSIKRAEIAGELAARL
                     GLTTTADTDVEELAKARTAAA"
     aSModule        complement(26435..29710)
                     /complete
                     /domains="nrpspksdomains_SAVERM_RS37805_PKS_KS.1"
                     /domains="nrpspksdomains_SAVERM_RS37805_PKS_AT.1"
                     /domains="nrpspksdomains_SAVERM_RS37805_PP-binding.1"
                     /locus_tags="SAVERM_RS37805"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(27170..28048)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37805_PKS_AT.1"
                     /evalue="7.40E-62"
                     /label="SAVERM_RS37805_PKS_AT.1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1501"
                     /protein_start="1208"
                     /score="201.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRPGMFAELFVAFPELQRHLRLDETTARVLFPPTAFDE
                     ASRKEQQERITDTTVAQPALGLTGLAAFQLLTRAGIRPAMAAGHSYGELAALAAAGALT
                     PDALVRTSRGRAAAVLGAAGDGDPGTMAAVAAGEPEVAAALAAAGLDGSVVTANRNSPR
                     QTVISGPTDDVLTAVERLRAQGLGAKRIPVACAFHSPLVAAAGEAFAKVLADVPVGATD
                     FPVWSNRTAARYPESPEAIRAELAAQIGAPVRFADQIEAMYEAGARVFVEAGPGSVLTR
                     LVGTVLGDRPHR"
     CDS_motif       complement(27731..27811)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0006"
                     /evalue="5.20E-08"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1314"
                     /protein_start="1287"
                     /score="24.8"
                     /tool="antismash"
                     /translation="GIRPAMAAGHSYGELAALAAAGALTPD"
     CDS_motif       complement(28001..28048)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0005"
                     /evalue="8.90E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1224"
                     /protein_start="1208"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LFPGQGSQRPGMFAEL"
     aSDomain        complement(28394..29710)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37805_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="1.20E-127"
                     /label="SAVERM_RS37805_PKS_KS.1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1093"
                     /protein_start="654"
                     /score="418.3"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAVVGMACMFPGAPDLAAFWANVLAGADAVTEVPATRWDADLYHD
                     LNGAGEKTPSRWGGFLPEIPFEPLRYGIPPASLPAIEPVQLLALEAARRALEDSGYGSR
                     SFDRARASVVFGAEAGSDLSNAMTLRSVLPAYLGTLPPALAEQLPRLTEDSFPGILANV
                     IAGRIANRLDLGGANYTVDAACASSLTAVDVACKELSGGTSDLVLCGGADLHNGINDYL
                     LFASAHALSPSGRSAPFDSAADGIALGEGVGCVVLKRLADAERDGDRIYAVIKGVGSAS
                     DGRALGLTAPRPEGQYNALTRAYRNAGVSPAEVGLVEAHGTGTVVGDRTELGSLTRVFE
                     EAGAEPGRCALGSVKSQIGHTKCAAGLAGLIKASLALHTGVKPPTLHLAEPNPAWDAQS
                     SPFAFHTEARPWPAAPAERVAGVSAFGFGGTNFHVVLRAY"
     CDS_motif       complement(28613..28657)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0004"
                     /evalue="6.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="1020"
                     /protein_start="1005"
                     /score="9.4"
                     /tool="antismash"
                     /translation="GSVKSQIGHTKCAAG"
     CDS_motif       complement(28718..28762)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0003"
                     /evalue="3.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="985"
                     /protein_start="970"
                     /score="10.3"
                     /tool="antismash"
                     /translation="VEAHGTGTVVGDRTE"
     CDS_motif       complement(29138..29185)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0002"
                     /evalue="6.70E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="845"
                     /protein_start="829"
                     /score="12.3"
                     /tool="antismash"
                     /translation="GANYTVDAACASSLTA"
     CDS_motif       complement(30191..30241)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS37805_0001"
                     /evalue="3.80E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="SAVERM_RS37805"
                     /protein_end="494"
                     /protein_start="477"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="LAAPLSARGAAVGVLMG"
     misc_feature    complement(31316..31318)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(31737..31755)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.54"
                     /tool="antismash"
     misc_feature    31834..31849
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.23"
                     /tool="antismash"
     misc_feature    32010..32028
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.09"
                     /tool="antismash"
     misc_feature    complement(32021..32038)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.78"
                     /tool="antismash"
     misc_feature    32034..32047
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.32"
                     /tool="antismash"
     misc_feature    complement(32034..32047)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.33"
                     /tool="antismash"
     misc_feature    32038..32051
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(32040..32053)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.1"
                     /tool="antismash"
     misc_feature    complement(32043..32052)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     gene            complement(32416..33966)
                     /db_xref="GeneID:41544434"
                     /locus_tag="SAVERM_RS37810"
                     /old_locus_tag="SAV_7363"
                     /old_locus_tag="SAVERM_7363"
     CDS             complement(32416..33966)
                     /codon_start=1
                     /db_xref="GeneID:41544434"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066: alpha/beta hydrolase domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062056.1"
                     /locus_tag="SAVERM_RS37810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7363"
                     /old_locus_tag="SAVERM_7363"
                     /product="carboxylesterase family protein"
                     /protein_id="WP_042494035.1"
                     /transl_table=11
                     /translation="MTTADSRASAPGSAEPVVPTAAGTVRGRLEGGLAVFRGVPFAEPP
                     VGDARFAAPRPVRAWDGTRDAFAFGPPPPQETGIQGRAALLDAPTGDDWLTVNVWTPDP
                     DPGARRPVMVWIYGGAYKLGHSGSPGYDARRIARDGDVVVVTLNYRVGIEGFARVDGAP
                     ANRGLLDQVAALEWVRENITAFGGDPGRVTVFGESAGAGSIASLLAMPSASGLFRRAIA
                     QSVPGTYFSDELAKDIAAAIAAEAGLRPTAADLSTVDPRQLPAAGEALAATMRQYEDRW
                     GPVVHTLTPFSPVVDGEVLPTTPWQALAAGTARDVELIVGHNSEEFRLFVLLSGQLGKI
                     TDGEARAALRRFGPGPDAEQAYRTGFPDASPGELYERVMSDWLFHMPSLHLAEAQLTGG
                     GRAHVYELTWPAPGNGGVLGACHGLDIPLLFGTFDADLGSLLFAGTEPSPEAEALSSRF
                     RASWTAFARTGDPGWPTYDTERRLVQVLDAAPEVIPYPEETSRRLWERHTFPALPLIQ"
     misc_feature    34174..34189
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            complement(34232..34846)
                     /db_xref="GeneID:41544435"
                     /locus_tag="SAVERM_RS37815"
                     /old_locus_tag="SAV_7364"
                     /old_locus_tag="SAVERM_7364"
     CDS             complement(34232..34846)
                     /codon_start=1
                     /db_xref="GeneID:41544435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044647.1"
                     /locus_tag="SAVERM_RS37815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7364"
                     /old_locus_tag="SAVERM_7364"
                     /product="hypothetical protein"
                     /protein_id="WP_010988759.1"
                     /transl_table=11
                     /translation="MDSEPGTGPARHYDPGRQLAQFTGRMLVVCPRCGGRALVVPRPGL
                     PAPRYFSELLFQPRRLACGGCGTVADREPEMRGAGLVGAVPGGSEDPFFRRPLWLQTRC
                     VGRILWAYNEEHVDELSAYVGARVRERGGVRPTRAMFARLPAWMKRADQRSEVLAGLET
                     LRALAERSAPADRSDAAHERGDRPRPYGSLYFRGGPYEARS"
     gene            35101..36957
                     /db_xref="GeneID:41544436"
                     /locus_tag="SAVERM_RS37820"
                     /old_locus_tag="SAV_7365"
                     /old_locus_tag="SAVERM_7365"
     CDS             35101..36957
                     /NRPS_PKS="Domain: ECH (346-526). E-value: 7e-22. Score:
                     69.8. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS37820_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:41544436"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380334.1"
                     /locus_tag="SAVERM_RS37820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7365"
                     /old_locus_tag="SAVERM_7365"
                     /product="hydrogenase maturation protein"
                     /protein_id="WP_037647125.1"
                     /transl_table=11
                     /translation="MHILLVASAFNSLTQRAHAELRDRGHTVAVELALPGGSLPEAVRR
                     HAPQLILAPMLKTAIPREVWSAHTCLVVHPGPVGDRGPSSLDWAIHEGADQWGVTVLQA
                     DEEMDAGDVWASVPCLLPPVSKSDLYRGEVADAALAAVLLAVERFATGTFVPRKQADQA
                     GQGGGQGGGEADQVGQSVARPEGAHPRTRPYLDQSVRRIDWAEDSTRTVVRKLRAADSQ
                     PGVLDVLLGDAWYLHGGHPESVLRGHPGELLATRAGAICRATKDGAVWIPELRPRRAPG
                     QPPTFKLPAVQALGDRLPPLREHTVPLFPDARHPTWTDIRYREEGNAGFLSFSFPGGAM
                     STAQCRRLLDAYRDACTRPTSVLVLGGERDFFSNGIHLNVIEAADDPGAESWANINAID
                     DLVEAVLTTTDRLVVSAVAGNAAAGGVMLALAADEVWCRAGAVLNPHYRLMGLYGSEYW
                     TYTLPRRVGPAAAERLMREALPVSAASARRTGLVDRVMECGPQEFAAEVGRLAARLAAL
                     PGTASRITAKKRELDRQESVIPPAAFREQELARMRRTFLDPDAPYHALRRAFVRKERPR
                     RTPPHLSPAAVAPSGQIPSEAHVTGTAPHGVSPRPDGWYEES"
     aSDomain        36139..36678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS37820_ECH.1"
                     /evalue="7.00E-22"
                     /label="SAVERM_RS37820_ECH.1"
                     /locus_tag="SAVERM_RS37820"
                     /protein_end="526"
                     /protein_start="346"
                     /score="69.8"
                     /tool="antismash"
                     /translation="RLLDAYRDACTRPTSVLVLGGERDFFSNGIHLNVIEAADDPGAES
                     WANINAIDDLVEAVLTTTDRLVVSAVAGNAAAGGVMLALAADEVWCRAGAVLNPHYRLM
                     GLYGSEYWTYTLPRRVGPAAAERLMREALPVSAASARRTGLVDRVMECGPQEFAAEVGR
                     LAARLAALPGTASRITA"
     gene            37006..38094
                     /db_xref="GeneID:41544437"
                     /locus_tag="SAVERM_RS37825"
                     /old_locus_tag="SAV_7366"
                     /old_locus_tag="SAVERM_7366"
     CDS             37006..38094
                     /codon_start=1
                     /db_xref="GeneID:41544437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124081.1"
                     /locus_tag="SAVERM_RS37825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7366"
                     /old_locus_tag="SAVERM_7366"
                     /product="hydrogenase expression protein HypE"
                     /protein_id="WP_010988761.1"
                     /transl_table=11
                     /translation="MTAATPDTVGAADAGGAPADETPTIHILWINAGLSCDGDSVALTA
                     AMQPSIEEIVLGVLPGLPKIAVHWPLIDFECGPVGGSDTFIEWFFKGERGEIDPFVLVV
                     EGSIPNESIKPEGYWCGFGDNPETGQPITTSEWIDRLAPKALAVVAIGTCATYGGIHAM
                     AGNPTGAMGVPDYLGWDWKSQAGIPIVCVPGCPIQPDNFSETLTYLLYQAAGAAPMIPL
                     DDKLRPTWLFGATVHEGCDRAGYYEQGQFALTYDSPKCLVKLGCWGPVVKCNVPKRGWM
                     NGIGGCPNVGGICIACTMPGFPDKFMPFMDEPPGAKVSSSASGAYGAVVRKLRTLTART
                     VDKEPKWRHTGDRITTGYRPPW"
     gene            38175..39959
                     /db_xref="GeneID:41544438"
                     /locus_tag="SAVERM_RS37830"
                     /old_locus_tag="SAV_7367"
                     /old_locus_tag="SAVERM_7367"
     CDS             38175..39959
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124082.1"
                     /locus_tag="SAVERM_RS37830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7367"
                     /old_locus_tag="SAVERM_7367"
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="WP_010988762.1"
                     /transl_table=11
                     /translation="MASTTKAAGDGSGLVEMAWDPITRIVGSLGIHTKIDFKQKRVAEC
                     YSTSSVFRGYSVFMRGKDPRDAHFITSRICGICGDNHATCSVYAQNMAYGVKPPHLGEW
                     IINLGESAEYMFDHNIFQENLVGVDYCEKMVKETNPGVLELAERTEAPHAGDHGYRTIA
                     DIMRSLNPIEGDFYREALQVSRYTREMFCLMEGRHVHPSTLYPGGVGTIASVQLFTDYL
                     SRLMRYVEFMKRVVPLHDDLFDFFYEALPGYEEVGRRRVLLGCWGALNDPEYCDFTYAN
                     MTDWGRRMFVTPGIIVDGKLVTNDLTEINLGIRILLGSSYYEDWQGQEQFVTHDPLGNP
                     VDPRHPWNQHTIPAPQKRNFDDKYSWVMSPRWFDGKDHLALDTGGGPIARLWSTALSGL
                     VDTGYVKATGHSVVINLPRTMTKPETTFEWKIPRWSNALERNRARTYFQAYTAAVALHF
                     AEKGLEEVRAGRTQTWEKFEVPDESIGVGFTEAVRGVLSHHMVIRDGKIANYHPYPPTP
                     WNASTRDSFGTPGPYEDAVQNTPIFEENTPENFKGIDIMRAVRSFDPCLPCGVHMYVGG
                     GKTVQKMHVPTGLSGLGG"
     misc_feature    38189..38198
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            39956..40546
                     /db_xref="GeneID:41544439"
                     /locus_tag="SAVERM_RS37835"
                     /old_locus_tag="SAV_7368"
                     /old_locus_tag="SAVERM_7368"
     CDS             39956..40546
                     /codon_start=1
                     /db_xref="GeneID:41544439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237514.1"
                     /locus_tag="SAVERM_RS37835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7368"
                     /old_locus_tag="SAVERM_7368"
                     /product="hypothetical protein"
                     /protein_id="WP_010988763.1"
                     /transl_table=11
                     /translation="MSAVSATNRVTAEQTGRRIEDVLDRLAATGDPAAGAAAEELVRTL
                     MEFYGSGLARILHLLSSAPGGPRPPGDPLAALLGDELVASLLVLHDLHPEDRDVRIARA
                     LDSVRDQALEVVAFDETSGTLRLRTRAGAGCGCAGTGTAAVQAAEDALACFAPEVTAVE
                     MQPAAAPGEPALLQIGTGPNSGAVARPAAAKTA"
     gene            40543..41211
                     /db_xref="GeneID:41544440"
                     /locus_tag="SAVERM_RS37840"
                     /old_locus_tag="SAV_7369"
                     /old_locus_tag="SAVERM_7369"
     CDS             40543..41211
                     /codon_start=1
                     /db_xref="GeneID:41544440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124084.1"
                     /locus_tag="SAVERM_RS37840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7369"
                     /old_locus_tag="SAVERM_7369"
                     /product="DUF5947 family protein"
                     /protein_id="WP_010988764.1"
                     /transl_table=11
                     /translation="MSGTRTPARAPGPGPRAPGLRRFLTERPPRQERCELCAVAVAEAD
                     HRHLVDIEKRALVCACVSCALLMEQPGAAAGRFRAVPNRYLTDPDHRLDDGAWEALQIP
                     VGVAFFFRNAALDRLVALYPSPAGATESELEPSAWTTVLGDSRLAVLLEPDVEALLLRR
                     TDGRCECYLVPIDICYELVGRMRLLWQGFDGGAEARAALETFFEHVVRRAKPVREVGRP
                     "
     gene            41208..41900
                     /db_xref="GeneID:41544441"
                     /locus_tag="SAVERM_RS37845"
                     /old_locus_tag="SAV_7370"
                     /old_locus_tag="SAVERM_7370"
     CDS             41208..41900
                     /codon_start=1
                     /db_xref="GeneID:41544441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474048.1"
                     /locus_tag="SAVERM_RS37845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7370"
                     /old_locus_tag="SAVERM_7370"
                     /product="DUF6084 family protein"
                     /protein_id="WP_010988765.1"
                     /transl_table=11
                     /translation="MTEFSFECTGVRADRYAAGPTLLFRLRVTAADNARVHALALRCQI
                     RIEPARRGYESAEADGLADLFGERSRWGNTLQPVQFAQVSLMVPGFTGETEVDLVVPCT
                     YDMDIAATRYLAALKGGEVPLLMLFSGTAFTGAAGFRVEPVPWDREAAFRMPVSAWREM
                     VEQHFPGCGWIRLPRDTMDALLAYRSQRALPSWEATVRALLEEKGTTDPPRKDPYLALT
                     RTTGGTDL"
     gene            41897..43333
                     /db_xref="GeneID:41544442"
                     /locus_tag="SAVERM_RS37850"
                     /old_locus_tag="SAV_7371"
                     /old_locus_tag="SAVERM_7371"
     CDS             41897..43333
                     /codon_start=1
                     /db_xref="GeneID:41544442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474046.1"
                     /locus_tag="SAVERM_RS37850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7371"
                     /old_locus_tag="SAVERM_7371"
                     /product="hypothetical protein"
                     /protein_id="WP_010988766.1"
                     /transl_table=11
                     /translation="MTVTAFAAQTEARFALARQVADAVLFEGYVLYPYRASAAKNRLRW
                     QFGVLVPPEWGADCEEHDFQHTECLMEPKAGATLSVELRFLRARRRTVQRIRPDGGFDT
                     VPELRLDDRVLVPWDEGAEERVEVVAAVDELLGDGVTVPFTRPALEEDEPVLDATGRPV
                     GRLVRRCEEISGAVRLSARELDGPYRTLRLTAVVENTSTWTPPQGRSADRDAALPHSLV
                     ATHLLMALSAGSFLSMTDPPEWAKGAIATCRNLHTWPVLAGEPGRADLVLSSPIILEDH
                     PAIAPESPGALYDATEIDEILALRTAALTDEEKREARGTDERAAAVIDLADSMPAEVLE
                     RLHGAVRSLREVTAPPSAAGPAAGGFPDEYGVRRPDTPWWDPASEAGFDPQHDRVVVDG
                     RSLGAGSRVLLRPGLRRTDAQDLFLQGRSAQVEAVLHDVDGGVHLAVTVEGDPGADIRR
                     EQGRFLYFQPDEVTPLEDDA"
     gene            43330..43881
                     /db_xref="GeneID:41544443"
                     /locus_tag="SAVERM_RS37855"
                     /old_locus_tag="SAV_7372"
                     /old_locus_tag="SAVERM_7372"
     CDS             43330..43881
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474044.1"
                     /locus_tag="SAVERM_RS37855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7372"
                     /old_locus_tag="SAVERM_7372"
                     /product="hydrogenase maturation protease"
                     /protein_id="WP_010988767.1"
                     /transl_table=11
                     /translation="MSGPREVPPRTLVAGIGNIFLGDDGFGVETARRLAERQLPAHIEV
                     VDIGVRGVHLAYQLLDGYDTLILVDATARGEAPGTLYLIEHDSPGGGEPEGAPVLDGHR
                     MTPDTVLALLDTLCAGTGGQPPRRTLIVGCEPASVEEGIGLSPPVSDAVPEAVRLIDEL
                     LRADEPGESAPRATADGAAK"
     gene            44207..44602
                     /db_xref="GeneID:41544444"
                     /gene="hypA"
                     /locus_tag="SAVERM_RS37860"
                     /old_locus_tag="SAV_7373"
                     /old_locus_tag="SAVERM_7373"
     CDS             44207..44602
                     /GO_function="GO:0008901 - ferredoxin hydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544444"
                     /gene="hypA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006075.1"
                     /locus_tag="SAVERM_RS37860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7373"
                     /old_locus_tag="SAVERM_7373"
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="WP_010988768.1"
                     /transl_table=11
                     /translation="MHEMSVALAVIDQVEQAAQQAGDVTAVRSVRLQVGELAGVVPDSL
                     SFCFELACAGTVLEGADLVTEEVPGRARCAPCAREWSVGMPPRLSCPECGGARVDLLSG
                     RELQIVSVHWEDGRTHAQTREPISEER"
     gene            44606..45433
                     /db_xref="GeneID:41544445"
                     /gene="hypB"
                     /locus_tag="SAVERM_RS37865"
                     /old_locus_tag="SAV_7374"
                     /old_locus_tag="SAVERM_7374"
     CDS             44606..45433
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016530 - metallochaperone activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544445"
                     /gene="hypB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124090.1"
                     /locus_tag="SAVERM_RS37865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7374"
                     /old_locus_tag="SAVERM_7374"
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="WP_010988769.1"
                     /transl_table=11
                     /translation="MCRVVDLHQAVLAKNDASAHTLRAELAARGTAVVNLLSSPGSGKT
                     ALLERELLLARERSVPVAALTADLATENDARRLARSGVPVKQVLTDGLCHLEAGMLSRH
                     LDGWLPDNTRLLFVENVGNLVCPASYDLGETLRVVLASVTEGEDKPLKYPTAFGLAHLV
                     VVTKTDIAEAVDFDEAAFRAHVEQVNPGVEVLLTSARRGRAIGALLDRALAAADGAPLH
                     RPVMARRTDVLGPAGPAHDHGHGDGHEHAHTGPAHDHGHAHPDGTGAMAQTRS"
     gene            45469..47835
                     /db_xref="GeneID:41544446"
                     /gene="hypF"
                     /locus_tag="SAVERM_RS37870"
                     /old_locus_tag="SAV_7375"
                     /old_locus_tag="SAVERM_7375"
     CDS             45469..47835
                     /EC_number="6.1.2.-"
                     /GO_function="GO:0003998 - acylphosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544446"
                     /gene="hypF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627003.1"
                     /locus_tag="SAVERM_RS37870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7375"
                     /old_locus_tag="SAVERM_7375"
                     /product="carbamoyltransferase HypF"
                     /protein_id="WP_010988770.1"
                     /transl_table=11
                     /translation="MPRRRRVTVRGVVQGVGFRPYLYGLATELALAGHVTNTPEGVVVE
                     VEGTPSAVDRFCDRIAAQAPPLARVESVHHQDLPATGGGAFTILASRADGPVRTLVSPD
                     MATCADCLDELADSADRRYRHPFVNCTHCGPRFTIVTGVPYDRAHTTMAGFAMCPDCAR
                     EYADPADRRFHAQPVACPACGPSLRLLVGRQPLDGRPQSVAGADPVTEARTLLARGAIL
                     AVKGLGGYHLACDASDPAAVALLRRRKARGDKPFAVMARSADDIEHLVRLGPEERSLLE
                     GGTRPVVLLRRRTDPSYPAGAPRPAEAVAPGSPDLGVMLPYTPLHHLLLGLPGDAEGPR
                     LLVMTSGNVAGEPIVTDDAEALERLAPLADAWLTHDRPIQVPCDDSVVRVSDGKPLMIR
                     RARGYAPLPVPLPLSVRPALAVGGDLKNAFCLGEDRRAWLSAHIGDMDDLGTQRAFGRA
                     TAQLESVTGVRPSMLVADRHPGYRSARWADRNAAGRPVVRVQHHHAHVAAAMAEHGLEG
                     TRPVIGVAFDGTGHGDDGAVWGGEILLADYDGFTRFGHLRYVPLPGGDAAVRRPYRMAL
                     AHLRAAGIGWSDDLACVAACPPDERRVLERQLERDLNCVPTSSMGRLFDAVSSLAGVCH
                     RAGYEAQAAVELEAAALNAPVEDVTAYAFALRASEPDGGGAVRADPAPVLAAIVGDLRA
                     GTEPALVAARFHRAVTGLVHRICVRARERHGLDTVALTGGVFANTLLSSACATALREDG
                     FTVLRHHLVPPGDGGLALGQLMVAARDTARTATTG"
     gene            47896..48216
                     /db_xref="GeneID:41544447"
                     /locus_tag="SAVERM_RS37875"
                     /old_locus_tag="SAV_7376"
                     /old_locus_tag="SAVERM_7376"
     CDS             47896..48216
                     /codon_start=1
                     /db_xref="GeneID:41544447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380324.1"
                     /locus_tag="SAVERM_RS37875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7376"
                     /old_locus_tag="SAVERM_7376"
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="WP_010988771.1"
                     /transl_table=11
                     /translation="MCLAVPGRVLDIEERDGTRMATVDFGGVVKEVCLEYLPDLQVGEY
                     AIVHVGFALQRLDEESAKQTLELFAQLGMLQEEFGDPWEQAAEAGGATPPVGDAVIEEV
                     RK"
     misc_feature    complement(47929..47943)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            48213..49337
                     /db_xref="GeneID:41544448"
                     /gene="hypD"
                     /locus_tag="SAVERM_RS37880"
                     /old_locus_tag="SAV_7377"
                     /old_locus_tag="SAVERM_7377"
     CDS             48213..49337
                     /GO_function="GO:0016530 - metallochaperone activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41544448"
                     /gene="hypD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380323.1"
                     /locus_tag="SAVERM_RS37880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7377"
                     /old_locus_tag="SAVERM_7377"
                     /product="hydrogenase formation protein HypD"
                     /protein_id="WP_010988772.1"
                     /transl_table=11
                     /translation="MKYIDEFQDPELARRLLDDIHSTVTRPWALMEVCGGQTHTIIRHG
                     IDQLLPEQVELIHGPGCPVCVTPLEVIDKALEIASRPEVIFCSFGDMLRVPGTGRDLFQ
                     VRSEGGDVRVVYSPLDALRIARQNPDREVVFFGIGFETTAPPNAMTVHQARRLGIPNFS
                     LLVSHVRVPPAIEAIMSAPNCRVQAFLAAGHVCSVMGVGEYPELAERFRVPIVVTGFEP
                     LDILEGVRRTVLQLERGEHTVDNAYARAVRPEGNPAAQAMLEDVFEVTDRAWRGIGVIP
                     DSGWRLSPKYRDHDAEYRFSVDGIQTREPAECRSGEVLQGMLKPHECEAFGTVCTPRTP
                     LGATMVSSEGACAAYYLYRRLDITTAAREASPVV"
     gene            49330..50406
                     /db_xref="GeneID:41544449"
                     /gene="hypE"
                     /locus_tag="SAVERM_RS37885"
                     /old_locus_tag="SAV_7378"
                     /old_locus_tag="SAVERM_7378"
     CDS             49330..50406
                     /codon_start=1
                     /db_xref="GeneID:41544449"
                     /gene="hypE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380322.1"
                     /locus_tag="SAVERM_RS37885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7378"
                     /old_locus_tag="SAVERM_7378"
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="WP_010988773.1"
                     /transl_table=11
                     /translation="MSETTDLRGPATLEAWTCPAPLRDRPRVVMGHGGGGALSAELVQH
                     VFAPAFGGEVLAQMGDAAALSLGGVRLAFSTDSFVVRPLFFPGGSIGDLAVNGTVNDLA
                     MSGARAAYLSCGFILEEGVEVEVVARVAEALGAAARTAGVEVATGDTKVVEAGHGDGIF
                     INTAGIGLIPAGVDLRPQRVVPGDVVIVSGAIGVHGVAIMSVREGLEFGVEIESDCAAL
                     GGLVDAMLAVTPDLHVLRDPTRGGLAAALNEIAAASGAGVVVRERDVPVPPAVANACAI
                     LGLDPLYVANEGKLVAFVPREHADAVLGAMRAHPLGADARIIGEAVEAHPGMVVARTGL
                     GGTRVVDLPIGEQLPRIC"
     gene            complement(50469..50765)
                     /db_xref="GeneID:41544450"
                     /locus_tag="SAVERM_RS37890"
                     /old_locus_tag="SAV_7379"
                     /old_locus_tag="SAVERM_7379"
     CDS             complement(50469..50765)
                     /codon_start=1
                     /db_xref="GeneID:41544450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124095.1"
                     /locus_tag="SAVERM_RS37890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7379"
                     /old_locus_tag="SAVERM_7379"
                     /product="hypothetical protein"
                     /protein_id="WP_306292883.1"
                     /transl_table=11
                     /translation="MDETRQQDNPSAHRSFHPAEHAGDRGRGRTKSAEETKSVPGETAK
                     SGSARGEEYAEESEEGRQDTGRRGRSQRPSGSKDASSYTGVDPKDPPSRHRPG"
     gene            complement(51271..51639)
                     /db_xref="GeneID:41544451"
                     /locus_tag="SAVERM_RS37895"
                     /old_locus_tag="SAV_7380"
                     /old_locus_tag="SAVERM_7380"
     CDS             complement(51271..51639)
                     /codon_start=1
                     /db_xref="GeneID:41544451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569985.1"
                     /locus_tag="SAVERM_RS37895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_7380"
                     /old_locus_tag="SAVERM_7380"
                     /product="DUF6479 family protein"
                     /protein_id="WP_037647128.1"
                     /transl_table=11
                     /translation="MNTTHYEAIASNAAFGMFAAFVGGLVIVGALVWAVRFGTKVRRRE
                     PGPPRREEQPTLPESGPVHETRQRREPDEVPRAANESERLTPHDLHASGSKPSENQQRP
                     RWDEGAGGSFGSGGPGRS"
ORIGIN
        1 gccctgtgcc gggcctccgc gctgtacacg tgcgtgctgg gggcccgcgc gttctacgag
       61 caccaccggg cgcaccggga tccgttctac acggaccggg tcatccattc gcccgccgtg
      121 ccggtcttcc gagacgaccg cgggcgcctg ctcgacaagc cgtatccggt cggcttcctc
      181 accgccgcgg cgccgaatgc cggggtcgtg ctgcgcagcg cgccggagcg ggcccccgag
      241 ctgccgcggg ccctcgcggc acgcgccgag cgggtgctgg agacggcggt gacgcacggc
      301 taccggcggc tggtgctggg cgcctggggc tgcggagtgt tccggaacga ccccgcgcag
      361 gtggcggggg cgttccacgg gctgctgggt cccgggggcc ggttcgccgg gcacttcgag
      421 cacgtcgtgt tcggcgtcct cgaccggacg ccggggacgg cgaccagagg cgccttcgag
      481 cgtgcgttcg atggcgaggt gcggggcgct cagcgccagc cgtagcgctc ccgcagccgg
      541 tgcaccacca ggttgaaccg catccggtcc agggcgcagg cctcccgccg catgccgctc
      601 tcgtgcagcc gcagcacgcg gtccacggcc acccaggagt cgcgtcccga cctgtcccag
      661 ggcccgctgc cgatcggcac ccactcccgg tcgccgtcgt gccgcttgct ggagagctgc
      721 accgccagca gcgtgccggc cgcctcccgg gcgacgacga gcaccgggcg gtccttgccg
      781 cgcccgtcgt tctcctcgaa gggcacccag gtccagacga tctcgccggg gtcggggtca
      841 ccgtcgtgcg cgggggagta ctcggtccgc acccggccca ccgtgcgggg ttcggcctcg
      901 gtggtcgcgg aagggccgtg gcggccggga atgtcttcat cggtaaaggc agtcacgcgg
      961 gtcacggtag agcctgctcg gcacggctcg ccgaacgggt acggcacttc gggcgtacgg
     1021 gggacaactc ccgtacgccc gaagccttac cgtttcaccc ctcgtccttc tccaccggca
     1081 ccttctccgt acgcgcgggc acgaacccgt tgagcccggc ggcgccgccg cccgccgtcc
     1141 cgttctggtt catcgacgcc agcagctggc gggccagacc cagccccgtg ccgcccatgg
     1201 tgagcgcctt ggcgaacatg tcgcccatgc cgtcggcgcc gttgagcagc accatgtgct
     1261 cgacgttgtt gaaggcgctc gcgcccgcct ggactatctc cggccagttc tcggcgagtt
     1321 gctgcgcgac caccgcctcc tggttctcgg cgagtgcggc cgcccgcgcc ttgatggcct
     1381 ccgcctccgc gagacccttc gcccgggtcg cctcggccac cgcgagcccc ttcgcctgcg
     1441 ccgcggccgc ctcggcctca ccggtggccc gggtcgccgt cgcggaggcg gcaccgcgcg
     1501 ccttcgtcgc ctcggcctcg gcgctcgccg ccgtcttcac ccgggtcgcc tcggccgcgg
     1561 ccgccagctc cgtctccttg gccttggcct gcgccgcgga gatgcgcgcg tcgcggtcgg
     1621 cctcggcgcg ggcccgggtc tcgtacgcct tcgcgtcggc cggcttgcgg acgtccgcct
     1681 ggagctgttg ctcacggcgg tgcgcctcga gttcggcgac ccgcgtctcc tggacgacga
     1741 cgtcctggcg cgcggcggcg tcggcgagcg gaccggcctg cttggccttg gcggccgcct
     1801 tgtcacgctc ggcctggtac ccggcttgca ggatctcgct gtcccgggtc gcctccgaca
     1861 tccgggacgc ggccaactgc tcggcctcgg tggcgagacg gttcgcctcc gcctgcgcga
     1921 tccgcgcgtc ccgctgcacg gcggccgcgt gcggcatggc caggttcttg atgtacccgg
     1981 tcgggtcctc gatctcgtgg atctggagcg agtcgacgat cagacccagc ttctccatct
     2041 ccgtaccgca cgcggcacgc gtctgcccgg tgagcttctc gcggtcgcgg atcatgtcct
     2101 cgaccgtcaa cccgcccacg atggaccgca gatgaccggc gaacacgttg tgcacccgct
     2161 ccgccatcag cttctgctgg tcgaggaagc ggcggcccgc gttggcgatc gacacgaagt
     2221 cgtcgcccac cttgaagatg accacgcccc gcaccttcag cggaatgccc tgcgtggtga
     2281 cgcagtccac ggacagctcg gtctcgttga gatcgagcga catcttgcgg accgcttgca
     2341 cgcccggcag caccagcgtg ccgcgccccg tcacgatgcg gaaacccatg ccttcttcaa
     2401 ggccttcggt ccgatgcttc gaaccggaga tgatcagtgc ttcgttgggc tccgcgacgc
     2461 gccacatgag cttgaagacc acaacgatga agatcagtgc gaggactgct gcccccgcca
     2521 cgacgccgac aatcatcggc atacgccccc tttggatggt gccctgacgg caccgaacga
     2581 acgggagtgt gctcctgtgc aaggccgaaa tacagacgct gacgcgtcct tgtcgcaatc
     2641 ttgacgcgta cggctctcac ctgggggacg ggcggctcaa ctgtcgtacg ccgcagccac
     2701 gtagacggtc cgcggcggca ggtactcgat caccatcacc accgtgcccg gctcgatccg
     2761 gtcctgcgcg gacgccggat acgccaggaa gtgttccgcg ccgccgcgca cccggacgat
     2821 cacctcgccg acgagcccgg ggccgatcgt gccggtgacc cgccccatca acccgaccat
     2881 cgacgcatcg tccatggtca cagcgtacgg cccgaactcc tccgggtcgc cgccgagtcg
     2941 gcgtccgtcg aggccggagg ccactgttcg tgccatcgcc ggtccgcctc cagctgggcg
     3001 gcgagcgaga cgagcagggg ttcgctgtgc gccgggccca gcaactgggc gcccacgggc
     3061 aggagtccgc cgtctcggcc gccctcggcc ggggaggggc cgccgtccac gaaaccggcg
     3121 gggacgttga cgcccggcca gcccagcacg ttccacggcc aggcgtaggg gcaggcggcg
     3181 atcatggcgc ggtcggtccc gaaaccgttc aggttcacca tcgagccgat gtgcggcggg
     3241 ggagcggcgg tcgtcggcgc gaggagtacg tcgtacacgt cgaagagcgc cccgacccgc
     3301 cggtgcagcc tggcctccgc cgcccgtgcc aggcgcaggg gtgctccgcc gagcagtcgg
     3361 ccgaggcggg cggcgtcgcg ggtgcgccgg tcgaggaggt ccggaaacgg cgcgtcgcgc
     3421 acccactccg ccaggccggc cgtggcccgc gggacgaacg tcagtccgat ccggccgtag
     3481 cgcggctccg cctcctcgac cacgtgcccg agcgccgcca gccgctccgc cagctcgagg
     3541 acccgcgccc gtacccgggg atcgagccgg gcgggcagcg ccgtgaacgg gggcttgagc
     3601 gagagggcga tccgcagccg gcccggctcg cgcccgacgg cctccaggac gccggtggcg
     3661 ggcgggcggt gcaggtcgcc cgcgtggttg ccgctcgccg cgtccaggag cagcgccgcg
     3721 tcggcgaccg tacgggcgag cgttccgttg accgtgatgc cctggaagga ctcggggcgc
     3781 ggccaggtgg agatccggcc gcgctgcggt ttgatgccga ccagatgcgt ccaggaggcc
     3841 gggatgcgga cggaacccgc accgtccgag cccagggcgg ccgggaccag gcccgcggcg
     3901 accgcggccg ccgagccgcc cgaggaaccg cccggcgtgt ggtccggatg ccagggattg
     3961 cgggtggcgc cgaaagcggg cccctcggtg aacggccact ggcccagctc gcaggtgttg
     4021 gtcttgccga cgatcaccgc cccggccgcc cgcagccgcc gtaccgcctc actgtcctcg
     4081 gcccgcggcg ggaactcgcc ccgacagccg aacgcggtcg gttcgcccgc cacgtccatg
     4141 tcgtccttca ccgccaccgg caccccgagc agcggccgcc gcgcccccgc cgccagctcc
     4201 cggtccgccg cctgtgcctc ggcgagcgag gcctcggcgc gcaccagccg gaacgcgttc
     4261 agcgagggct gcgtcgcctc gatccgggcc agcgtccgct cgacgagctc gcgcgaggtc
     4321 acctcgccgt cggccagggc ccgggcgcac cgggcgaggc cctcggcacg ctcgggaggg
     4381 gtgtcggcgc gttcggcagc catgcgggac acctccgggt ggacgacgtc taccgaacgg
     4441 taaccgcccg gcgcccgacg cggtacggga tctcgaactt ccgccccgga aacgggtgtt
     4501 caggggtgca tctggccgat gaatgtcggg aaagcgcttg ttccgagcgg aagttgcccc
     4561 ggtacggagc gccgccgccg tcttctgcaa agatgccgta cgtcatggtg cacataccga
     4621 acgagcccgt cccttcgccg tccgcaccac gctccgtgcc gacgagcgcc gatgtggcac
     4681 gcctggcggg agtctcgcgc gcgaccgtct cgtacgtgct caacaacacc agcgccgtcc
     4741 ggatcagcga gcccacgcgc cgccgcgtcc acgaggccgc caaggaactc gggtacgtcc
     4801 cgcacgccgc ggcccgcagc ctgcgcgccg ggcacagccg tatggtcctg atcccgacgc
     4861 cgaacgtgcc ggtcggaccg ctctacaacc agttcttcaa cgaactgcag tgggcgctca
     4921 gccgacttga gtacaccgtg gtgcagtacg gcgacctgtc gccgcacggc gacgaggcgg
     4981 cccgcgcctg ggccgagctg cggccggtcg ccgtcctcgt gcccggcggc gggctcgggc
     5041 cccagggcct ggccgtgctc aagcgctccg gcgcccgcgc cgtcgtcacc ctcggcgccg
     5101 aacgcgtcga gggcgcccac gcggtgctgc tggaccacga gggggtcggc cacagcgccg
     5161 gccggcacct gctcgcccgc ggccgccgcg cggtaggggt cgtggtaccc gaggagcccg
     5221 gcttggagat gttctccaag ccccggctcg aaggcgtccg gcgggccctc cagggcaccg
     5281 gggccaccgt caccgaactg ccgctcgcct acgaggagga ggccgcggcc cgcctcgccg
     5341 cgcgctggcg cccgctgggc ctggacgccg tcttcgcgta caacgacgag tacgcgatgc
     5401 tgctcatgcg cgccctccag gacgagggca tcgccattcc gcgggagacg gccgtgatcg
     5461 gcgccgacga cctgatgctc ggccggctgc tgcggccacg cctgagcacg gtccacatcg
     5521 agctgccgtc ggggcgcgac ctcgcggagc tggtcgatcg cgcggtacgc gatccgggcg
     5581 tcgcacccga ggtgcacgag gtgctcggca cgagggtcgt acagcgggaa tccagctgaa
     5641 cgtccgggcc cggctcacgg gtcacgggtc ccggggaacg ccctcgggcg attcggaccc
     5701 gactccccga ccgctccccg gagttgcgcc tgccccgggc ccggggcagg cggcccgttc
     5761 ctcatcacgg catgccgcga acgccgcacg ctcgaccggg gcgatgcctg atcctgagcg
     5821 ggtgctactc gccctgctgt gcctgagcct gcgcctgctg tgccgcgacc gccttgcgga
     5881 cctcgtccat gtccagcttc cgggcctgtc cgatcacgtc ctccagggct gcctcgggca
     5941 gggcgcccgg ctgggcgaac acggcgacct ggtcgcggac gatcatcagc gtcgggatcg
     6001 actggatgtc gaaggccgcg gccagctcgg gctgagcctc ggtgtcgacc ttggcgaaca
     6061 ccaggtccgg attggcctcc gccgccttct cgtagaccgg ggcgaactga cggcacggcc
     6121 cgcaccagga cgcccagaag tcgatcagga cgaactcgtt gtccgtgacc gtctggtcga
     6181 agttctcctt ggtgagctcc acggtgctgc tcatggcgtg tttccctctt cctggtgtcg
     6241 ggggctcggg gcaagccgct gtccacaacg ccaccctccg gcgccgtatt ccgcgcgcgt
     6301 acccgtgtgg ccagcacgca caccagctac cagactgacc ccatgacgga aacggaatcc
     6361 atcgcgtacg acgtcgtggt gctcggggcc ggtccggtgg gggagaacgt cgccgaccgc
     6421 acccgcgcgg ccggcctgtc caccgcggtc gtcgagagcg agctggtcgg cggcgagtgc
     6481 tcctactggg cctgcatgcc cagcaaggcc ctgctgcgcc cggtcatcgc ccgcgccgac
     6541 gcccgccgcg tgcccggcgt gagccacctc gcgcagggcc acctcgacac ggcagcggtc
     6601 ctcgcccacc gggactacga ggtctcgcac tggaaggacg acggccaggt cggctggctc
     6661 gacggcatcg gggccgacct gtaccggggg cacgggcgcc tgtccggacc ccgcgaggtg
     6721 acggtgacgg gccccgacgg tgatcgccgg gtactgaccg cccggcacgc ggtcgcggtg
     6781 tgcaccggca gccgcgccct gctgcccgac ctgccgggcc tcgaccaggt cgaaccgtgg
     6841 acgagccgcg aggccaccag cgctcaggcc gcccccggcc ggctgatcgt ggtcggcggc
     6901 ggtgtggtcg ccgtcgagat ggccaccgcc tggcgggcac tcggctccga ggtcacggtc
     6961 ctcgtccgcg ggaagggtct gttgccccgt atggagccgt tcgccgggga actggtggcg
     7021 gaggcgctca aggaggcggg cgccgacgtc cgcaccggca catcggtgtc ggcggtgacc
     7081 cgcgagggcc cgaccgtggt ggtgctgacg gacacgggcg accgcatcga ggcggacgag
     7141 atcctcttcg ccacgggccg cgccccgcgc accgacgatc tgggcctcga cacggtgggt
     7201 ctggagcccg gctcgtggct gtccgtcgac gacagcctcc gggtgacggg cagcgactgg
     7261 ctgtacgcgg tcggcgatgt gaaccaccgg gcgctcctca cccaccaggg caagtaccag
     7321 gcccggatcg cgggcgcggc catcgccgcc cgggcctcgg gcgtgcccct gctggaatcg
     7381 gatccctggg gcgcccacgc cgccaccgcc gaccacgcgg ccgtccccca ggtcgtcttc
     7441 accgacccgg aggcggcggc cgtgggtctc tccctcgccg aggcggagcg ggccgggcac
     7501 cacgtccgcg ccgtcgacgt cgagttctcc tcggtcgcgg gcgccggtct gtacgccgac
     7561 ggctaccgcg gccgggcccg catggtcgtc gacgtcaacc gcgagaccct cctcggcgtg
     7621 accttcgtcg gccctggcgt gggcgaactg atccactcgg cgacgatcgc cgtcgccggc
     7681 gaggtgccga tcggccggct gtggcatgcg gtgccctcgt atccgacgat cagcgaggta
     7741 tggctgcggc tcctggaggc ctaccgggac gcctagggcc tgtcgtcgga cgcgtcggtg
     7801 tcttggaccg gcaggacgcg tcggtctgtt gggccggccc ggtccgcgac gtcgcggcga
     7861 catcagccgc ggcgtccggg gcggcccctc gccgcgttgg cgcacgaccg gagtacggcc
     7921 cggtacgcgg gtcgtactcc ggctcgcgac gcaccgcccc ggagaccgcg gcctgaccct
     7981 gcccgagccg gaactcacca tggggcaggc cctttggaca cggcagcgcg ggcaccgcgt
     8041 cgggcgcccg cgattctgag ccgaccggcg ttctcggtcg ggcggcgcgc actcagtcgg
     8101 gcagcgcgaa ccccagtgcc gccgccgccc gttccggcgt cggctggctc caccgcagtg
     8161 ccatcgcctc gttcgacgac agcgaccgca gctccgcccg gtcgagatag agcatgccgt
     8221 cgaggtggtc cgtctcgtgc tggacgatgc gggcgggcca gccggtgaac tcctcgtcca
     8281 cggcgcgacc gtgctcgtcc agcgcggtca gccgcacccg ggcgggccgg gccaccacag
     8341 cctgccagcc cggcacgctg aggcagccct cgaagaacgc ggcccggtcg ctgccgacgg
     8401 cctcgtacga cgggttgacc agcacccgga agggctgcgg cacccgcccc cgcaccgccc
     8461 ccacctcctc cggcaccggc gccgggtcct cgatgaccgc gatccgcagc cccaccccca
     8521 cctggggcgc cgcgaggccg acgcccggcg ccgcgtgcat ggtcaggcgc agggcctcga
     8581 cgaagcgggc gaggagcccg ggtccgagct gcccgtcgta gggctcggcg ccgcggcgca
     8641 gcaccgggtc gccggccgcg acgatcggca acgggccgcc ggtggcgagg agttcctcga
     8701 cacggtcggc gagcgggcgg gaggcggagc gggtgtcggg gaccgtgcgg tcactttcgg
     8761 atgccatcgc gtcagcatgc caggcagatc gagcggcacg aggcccgtcc ccgcggccat
     8821 gtggcccagg tcacgtacat ccgcgggaac tcacccgcac tccgccccga ctactgaagc
     8881 gccacggccc tcccgggtcc cgtgccccga ggttgtccca cgtccccatt ccccattccc
     8941 cgtcccccgg agaagcccgc cgatgaccac cgctccctcc gccccagacg ctccctcgac
     9001 cacgacggac gagcccccgc agtccggtac gcccgggccc gccagatggg ccccgctgcg
     9061 ccccctggtc ctgcgcctgc acttctacgc cggcctgctc gtggccccgt tcctgctggt
     9121 cgccgcgctg accggattcc tctacgcggc ttcctaccag gccgagaaga tcgtgtacgc
     9181 gcatgagctg accgtccccg tcggcgacac cgagctgccg atctcccagc aggtcgccgc
     9241 cgcccgcaag gcccaccccg agggcacact cacggccgtg cgcccctccc cggaggcgga
     9301 cgcgacgacc agggtgctgc tgtccggcgt caagggcgtc gacgagggcc acaccctcgc
     9361 cgtcttcgtc gacccgtaca ccggcaaggt gcggggctcg ctggaacagt acggatcgac
     9421 cggcgcgctg cccctgcgca cctggatcga cgagttccac cgcgatctcc agctgggtga
     9481 gaacgggcgc ctgtacagcg aactcgccgc gagctggctg tgggtgatcg cgggcggcgg
     9541 cctcgtgctg tggttcgggc gtcggcgcgc gcagcgcaag gtgcgcggga cgagcgggcg
     9601 ccgccgcacc ctgggcctgc acggcacggt cggcgtctgg gccgcggccg gcttcttctt
     9661 cctctcggcc accggcctga cctggtccac ctacgccggc gccaacatcg acgaactgcg
     9721 cacctcgctc ggccaggcca ccccgtcggt gtcggcggcg gcggccggcg agcacgcggg
     9781 ccacgacgcc gcggcgggaa ccggcggtac cgagcacggc gtgggcctcg acaagatcct
     9841 cgccgccgcc cgtgccaagg ggctcggcga tcccgtcgag atcgtcccgc ccgccgacgc
     9901 gtcgtccacg tacgtggtga agcaggtcca gcgcagctgg cccgagaagc aggactcggt
     9961 ggccgtggac ccggcgaccg gcgaggtcac cgacacgctc cggttcgccg actatccgct
    10021 gctcgccaag ctgacccgct ggggcatcga cgcccacacc ggcgtcctgt tcgggctcgt
    10081 caaccagatc gcgttgatgg ccctcgccct gtccctggtc ctgctgatcg tctggggcta
    10141 ccgcatgtgg tggcagcgcg gccgggcctc cgccttcggc cggccgatcc cgcgcggcgc
    10201 ctggcagcag gtccctccgc agatcctcgt accgtgcatg gcggtgatag ccgtcctcgg
    10261 ctacttcgtg ccgctgctcg gcatcccgct ggcggtgttc atcgccgtgg acgtcgtcct
    10321 cggcgagatc gcccaccggc gtgggcagcg cacttacgga aggcaggtag cgtagccgga
    10381 cacgcggatg ccggagggag tcggacatgg cacagcgcga ggccaacagc ccgcaccgcg
    10441 gttcccggcg ccgcgggcag ggcgagctgg aggtccaggt gctcggcgcg ctgcgcgagg
    10501 cggacggccc ggtgaccgcg tcctgggtgc aggagcacct cggcggcgac ctcgcgtaca
    10561 ccaccgtggt gaccatcctg acccggctgc tggccaagga cgtcgtctcc cgcgagcggc
    10621 aggggcgttc cttcgcctgg acgccgaccg ccgacgtcgc gcgcctcgcc gcgctcaaga
    10681 tgcgccgcct cctcgacggt gaacgcgacc gcgaagccgt cctggccagc tttgtcaccg
    10741 cgctgccgcc ggacgacgaa caggtcctgc gcacactcct ggacgcggcg gacacggcgg
    10801 acggcggtac ggaaggctga cgcctcgtgg aggttttgtc ttcctgccgc tggtctcgcc
    10861 gctggtcctg ccgctgagcg cctggccggt ggcgcgcctg gccgagttgc acgcggccgc
    10921 acccctctga ggcccgtaca cggaaagagg ctgagccccg ttgccaccgg ggctcagcct
    10981 ctgcgtcatt gcgctacgga tacgtcgtag cgctacggat acgtcgtagc gcgacgggta
    11041 cgtcgttgcg ctgcggatgc gtacggcgct acggaacgag tgaacgcttc tcgtgcggac
    11101 ggatcaccgt gcctcgaagt cgcccgcgag cgccgaggcg atccgcagct gcgagtccgc
    11161 ctcgtcgtcc cgcccctggc gctggagcgt gcggcccagc atcaaccggg cgtagtgctc
    11221 cacggggtcg cgctcgacga ggatgcgcag ctcggcctcc gcacggccca actgggccga
    11281 gtggtagtag gaacgcgcca gcagcagccg cggcccggtc tgctccggca cctcgtcgac
    11341 cagcccgtcc agaatccgcg cggcgacggc gtagtccttg gcgtcgaaga acatctgcgc
    11401 gcgctcccag cgctccgcgg ccgtcccctg gtcgtagtac gtcgtttcca ctgctgacct
    11461 ccttcgacgc tcacaacggc ccggtttggt tgaatattcc acgactgggt cggggggcgg
    11521 tgccgccctt acagggccgc aagctccgcg ttcgcccgct ccgtcaccag cgtcagcaca
    11581 cgcccggccg tctccagatc ctgggccggg atgcccgcgt acagccgggt cgcgatctcc
    11641 ttgccgccgg cctggatgct ttcgaacagc tcccggccgc tgtccgtgag cgacacctga
    11701 ccgggtgccg gttcgtccag cagcttcgcg gcgatcagct cgtcgacggc ctgccgggcg
    11761 ggtgtttccc cggtcttcag cgcaccggtc aggcggtcga cgagccggtc gcgcgcgaca
    11821 gttccgccgg cggccgcggc cgcgtgcagg gccaccgact cctcgaacgt ggtgccggtg
    11881 cgggccagta cggtctccag caggccgcga ccggcgtagt gggcaaggcc tatgacctga
    11941 ccgttgacgg tggggttggt ggtgaggttg gtggtggggt tggtggtggt cacgactgct
    12001 cctctgcggc aggtgtgccg agttcggtgg atgtgccggg ttcgatcgat gcgtcgagtg
    12061 gtgcgtcgag cagagttctc agttcgtgcg tgaatcgcgt cgtgcgcggg ctgtcgaggc
    12121 cgcccaaggg ctggaggagc tgctccagca gccggtggac caccttgatc gcctgctggg
    12181 cgacctcgtg tccccgcggg gtgagcgaca gctggatcgc gcgcgggtcc gccgggtcgc
    12241 gggtccggtc gacgaggccg ccggactcca gcgcgcgggc cagcttcgag acgtagagcg
    12301 cttcgagtcc ggtgtggtcg gcgagctgcc gctggttggg cctgagcccg gtgcggtgca
    12361 tgccgaccag cgtggcgacc agcgaatact gcgcgtgcgt cagccccagc ggcgcgaccg
    12421 cccggtcgac cgcgacgcgc catttcatcg acagtcgcca gaccaggaaa ccgggggtcg
    12481 cgccctcggg ggccgtgtcg ctcaccgtgt tgctcatgac ggatactgta catagatact
    12541 atagccatag ctactatttt ctcgtggtgc gacgcaccgc atcccgaagg gacggggccg
    12601 atccggccag gggagggggg atggactgac ggaccgtccc ggccggggct aggtttgcca
    12661 catgagcaat cttgatcgcg aggcagtgcc cacgctgtgc ggcggccgtg ggttcgtggt
    12721 ggccgagccg gtgcgcgaac tcctcagccc ccgcaaggtc aagctcggtg agtccaccga
    12781 agtccgccgt ctgctgccca acctaggccg ccgtatggtc ggcgcctggt gcttcgtcga
    12841 tcactacggt cccgatgaca tcgccgacga gccaggcatg caggtcccgc cgcacccgca
    12901 catggggctc cagacggtca gctggctgca cgagggcgag gtcctccacc gcgactcgac
    12961 gggcagcctc cagacgatcc gcccgcgcga gctgggcctg atgacgtccg gccgcgcgat
    13021 cagtcactcc gaggaaagcc ccaagtcgca cgcgcggttc ctgcacggag cacagttgtg
    13081 ggtggccctg ccggacagtc accggcacac cgatccgcgc ttcgagcacc acgcggaact
    13141 gccggtcgtc acggcgccgg ggctccaggc cacgctgatc ctgggcgagg tcgacggcgc
    13201 gacctcgccc ggcacgacgt tcaccccgat cgtgggcgcc gacctgtccc tcgcgagcgg
    13261 cgccgacgta cgactgccac tggagccgga cttcgagtac gccgtcctgt ccatgtcggg
    13321 cgaggcccac gtcgacggcg taccggtcct gccgggctcg atgctctacc tcggctgcgg
    13381 ccgcagcgaa ctgccgctgc gcgcggagtc ggacgcgggc ctgatgctcc tgggcggcga
    13441 gccgttcgag gaggagctgg tgatgtggtg gaacttcatc gggcggtcca acgaggacat
    13501 cgcacaggcc cgttcggact ggatggcagg ctcccgattc ggtgaggtgg tggggtacga
    13561 cggcgctcca ctgcgcgctc ctgaactccc gccggtgccg ctgaaaccgc gcggaagggt
    13621 gcgctgacct ggggctccag ctcaagcgca ggcccctcgc gggacgtggc tgttcccgct
    13681 cgacaccccg ttttcccgag gggccgaccg ctcctgcgaa gtccatcgac ggacagtgct
    13741 gcgttctcgt gtctggacat ctgtaggcgg gtttggtcag cccaatgctg ggctgccgct
    13801 cgcgtgtagg gccaggccca tgctgacttc ggtgacttgt gctggggcaa ggtgccccaa
    13861 gtgcgtgggc gacgaagggg agaagaagtc cgtgacgagg gggcttttgt gagaatcccc
    13921 caatgccccg gcgtgccgct gctgccgtac tcaccccttg ggcggaccgc catggggaga
    13981 gtgtggctac agtgacggcc ctcggaagcg gcttgtcggc aagccgggct ctgcttcaga
    14041 acggggaacg gcagtcagca ggttctcgcc gacccaccgt caccgagtac agctctcact
    14101 cagccgccgt agccgcgctg cgccacagtg gcctgctccg gcgggcgcca ctgtccggcc
    14161 ccgcccgcgc cttgaagggc gcgacgtgcc gctcctcagc ccacgccacc cacacattgg
    14221 ttacacaccg tgaccgtcca gtaggatcga tccacgcgca tgtgacctcg ctggtgtggg
    14281 ggtgtgcgtg tcgtccggac tcggttcacg cttcgtcgtg gtgggtgagg tggccgtcgg
    14341 tgagccgcca gtagtgctgg tgaggagtta gttgccaggt ctcgtcggca gcgatcacct
    14401 gcgtgatcca ctcgtggagt tgcgggaggg catgcgctcg tagaacagcg cgggttgcag
    14461 cacgttcagt ggcatcgact gggtggacgt ctatgcggaa gccaaccatg tccgggtgga
    14521 tgccgcggcc gtagttgcgg gggttcggag cgacccattc ggctcccagg acgatggtcc
    14581 cgctgtcatg cccagtgagg aactgcaggt ccgtgacacg ggtcatgtaa gggccaagac
    14641 gctcgttgat gtcggtggtg gtcagtggcc aggcacggtg ccggggcagt cttcgatttc
    14701 gtgcggacat ggcaagcaga atggcagaag gtcactgtcg gccctcatgg gtgttctgtt
    14761 cggcggcggt ttccagaagc tggcgagcgg agttcgcgca gcggatcgcg gtctacgagt
    14821 gtgctgtccg gacggcagat gctcgcgtgg ccgtcgtact ggacgtagaa ccgtcgttcc
    14881 gatacagcac cagattcccg tccttctggt acgtgaacgt gtaggagccg ttctgggaga
    14941 ccaggtactg gtcggccacg agcatgtcac cgggcagcat gcggtcgcct tgggccgcgg
    15001 gccgttccgt gtcgtatatg tagccgaggg cctggtggtt gagtgtgctg gcgatggtgg
    15061 tgttcccgaa ccagggatcc atggcgtcgg gctcgttctg cccctgtggc gcgccccgtg
    15121 ctgcggcatg tatgtcaggt cggagtgctc gtactgccat tgggcccaca ggcggtcgat
    15181 gttggcgtgg tgcagccaga acaccgggtc gttcggggag ctcagcggcc tcatgtggcc
    15241 accgacccac tcgtgcaccc ggttgtggat gttcggcccg atccagcctt cgagctggtt
    15301 ccggaagctc gggttgctcg tcgtgtccca gggcgcgctg tcatagggcg tgatctgaag
    15361 gcagtcggcc acgtcctgag cggtgggcag cgagccgatg tgcaccccca gttccctggt
    15421 caaatagttc gcgccgatgt cgatctttag gcagacccat ttgccggcat cgaaggcaaa
    15481 actgatgtaa ccgtcgtaaa tgccgcggcg cttgagttcc agcagggcgt cgacgaatgc
    15541 cgatagctcg gctgtgttca tcattgcctg gtctctgcgg acgagagcca tcattgcttc
    15601 aagggtcagg tgttcgcccc ctacctttca gcgtctgacc ggatcaggca tccggcaaca
    15661 tatggacgga gaagttgaaa aggctacgga cggcgccgac gccgggggac ggacgacatg
    15721 tcggtgccga ggccttgggg cgcgcaacga gccttgccgt gcggtgcact tgaacaccgg
    15781 cgacgacggc acgccgttgg tcgcccaccc ccgagcggcc ctgggattcc cgctgtcggt
    15841 gcttgcggcc ctcggcgcgg tgggcggggc gttcgacgtc ggcctgccgg ttgacaccgc
    15901 gccaggtcga gccgtcacgc cgggggctcg gccgccagga gctgggtcgc ggccagttcg
    15961 cggtagaggt cgtcgtcgtc gaccaacgag tggtgggtac cgacggcgcg gacgccgccg
    16021 tgctccagga ccacgatctg gtccgcgtcg gtgaccgtgg acaggcggtg ggcgatcaag
    16081 aggaccgtgc accggcccgc ggcacgggcg acgagttcgc tcagggcctg ttcgttgcgg
    16141 gcgtcgagct gggccgtcgc ctcgtcgagg aggagcacct gagggcggcg gagcagggcg
    16201 cgggcgatgg cgaggcgctg tcgttcgccg ccggacaggg tcacgccgcg cgggccgacg
    16261 ggagtgtcca ggccctgggg caggcgggcg acgagcgcgt cgaggcgcgt gacggccagg
    16321 gcctcggcca actcctcagg ggtggccgag ggtgccgcgt acagcaggtt ctcgcggagg
    16381 gagccggcca tcaccgggga gtcctgctcg acgtacgcga tccgccgccg gacctcggca
    16441 cgcggcagtg cggagatgtc ctggccgccg atcctgatcg tgcccgcggt cggctcgtag
    16501 aagcgctgga ggagggagaa gagggtggtc ttcccggcgc ccgaaaggcc gacgagcgcc
    16561 gtctgcgtac cgccggggac cgtgaagccg acacctcgca gggcgggggc gcggcccggg
    16621 taggcgaact cgaccccggt cagctcgacg gcgggcggcg cggcgtgggc gggggcggcg
    16681 gcgggcggtg cgtcgatgtc gtcctcgacc ggcagcccgg cggcctcctg gatcctgccc
    16741 accgcgccca gcccctgctg gagttgggcg gccccgccga ccagctggga gaccggactc
    16801 gccaggaaga acacgtacag gaggaaggcg atcagctcgg agaccgacat cgtgcggttc
    16861 gccacgaagg tgccgcccac gccgagcacc accaggaacg cggtctggat ggcggcgccg
    16921 ccgaccatgg tgaccagcgc gctgtatcgg gcgccgacca ggccggccgc gtacgcctcg
    16981 tcgaccgcgt cctcggcggc cagcgtctca cggccctcgg cgccgttggc cttgaccgta
    17041 cgggccgcgc cgagggtgcg gtcgagcacg gcgccgaccg cgccgacgga gctctgggaa
    17101 cgggccactg cggccttgat ccggggcagg atcacggtga tcacgacgcc gaccagggtg
    17161 agcaccagca gggtgacccc gagcagccgg gcgtcgagcg ccgccatcat gaacagcgcc
    17221 ccggcgaagg tcagtacgcc gttgaccgtc atgatcaggc cctcggtggc cgcgctcttg
    17281 agcagggtgc tgtcggaggt gacgcgggcg atgaggtcgc cgggggcgcg ccggtccagt
    17341 tcggcgaccc gcagccggat cagacggtgc acaagaccgc gccgtacctg ccggaccacc
    17401 cgctccgaag tgcgttgctg gagccaggcg ttgaggccgg tcagcagggc gcccgcgacc
    17461 aggaacacgg cgagcagcgc caccggggcg accacgccgg cgccgtcgtc gaggcggtcc
    17521 aggatcgcct gcgcgaactt cggctgcacc agccccgaca cgctggccag cagagtgagg
    17581 acgagggaga gcagcagcac ccgccagtga ggccgcgcgt agccgatgag ggcggacaag
    17641 gagccggggg gagtagtggg cgtgggatcg tcggtcatga gcctcgtact ccgggcacgg
    17701 ccgactcggc cgtcagtgtt tcgaggcggt cggcggcgga ctcgctgccc cccgcggccc
    17761 ggaaggactc cccgacggcc tcggccgcct tccggtggcc ctgagccgga tcgaggacgg
    17821 cctcgacggc cgcgccgatc ctcgccgcgt cggcgcggcc gaaccgcagc cgtaccccgg
    17881 cgcccgcgtc cacgacctgg gcggccacga tcggctggtc gtcacggatc ggcgcgacga
    17941 cgagcgggac cccgtgccac agggcctcgc agacggtgtt gtgcccggcg tgacagacca
    18001 ccgcgtcgag ccgttccagc agggcgagtt gaggaacgta ccggcgtacg aggacggtgt
    18061 cgggcaccgg gtgctcgacc accccgccgg gatcgacgag cacggcccgc acccggtccg
    18121 cgatcccgcc cagcgcctcg gcggccgcgt tcaggaaacg ggcgccggcg tcgttgttgg
    18181 ccgtgccgag gctgacgagg acggtgggca gcgcggaggc ctccagccac tcccagggga
    18241 agtcgtcggg gcccgccggg cgggcggcga cggacggccc caccagccag acccggtccg
    18301 gcagttccac cgggccgagc agcgcgcgcg tggtgtacgc gagcaccccg tgcggagaga
    18361 accgcggatc cgcggcgccg gcgccgcccg tgatccggcg gcgcagctcc ccgagcagac
    18421 cgtcgagcca ggccgcgact ttgggcatcc cggccagcgg gtcgaccagt tcggcggacg
    18481 tggtggccga ggtcacccag ggccgcccga gcgactcggc gaccagcgcg cccgccaccg
    18541 cctgctggtc gcagacgacg acatcgggat cgtacgcctc gatcgccgcc cgcaccccgg
    18601 gcgccatggc gtccgccaac gggacgagga agctctccca gaggaactgg aaggcggccg
    18661 gtcccttcag gccggcgggc cgggaaagac cgtcctcggg cagcgcgcag gggaagacga
    18721 cggcgtccgc ccccgcgaga ccgcggacca gttccggatg gcccgcccag gcgatgtcgt
    18781 gcccgcgggc cgcgagggcc gccgcggtgc ccacggccgg gttgacgtgc ccgaccagcg
    18841 ggggcaccac gaacaggaat cggcccatct agcgggcctc ccgcagcgcg agcgcctcct
    18901 ggccgagcag ccagtcgcgt acgagggcgt acgtctcctt ggtggcctcc accagcaccg
    18961 agtggccgag accgggcagc acgaccgtac ggcagcgcgc cagggacgct tccagcatcc
    19021 cggtctgcgc ggcgagcttg gacgcgccgc cgaacacggc gaacaccggg cagcggatcg
    19081 cggacaggtc gtcgtcgagg agagagctga gcgggatctc ctgggcgagg gcggtctcgt
    19141 ccagcacccg gccggccgcc cggaacggcc gggcgttgcg ctcgcccggg ttctcccgca
    19201 gccactcctt gacctctcgg accaccaggc cgccctcctc gccgaccagg ccctcgtaca
    19261 tgctctgcgc ccaggcccgg cccggcggct cggcctcgat ggcgatgacg ctggcgaccc
    19321 gctcggggtg ggcggcggcc atggcgtacg cgatcgcccc gccgaaggag ttgccgacga
    19381 ggtgcaccgg gcggttcacc gccagtgcgt cgagcagtgc gtcgaggtcg cggacgaagt
    19441 cctccatgcg gtagccggtc ggcggccggg aggtcttgcc gtgcccgcgc aggtcgtaca
    19501 tgacgacgtc catgccgtcc tcggcgagct gcggcgcgag gctgaagtag tagctggcga
    19561 ggctgtcgat gagcatgccg tggatgagca ccacgacggg gcgcgggacg tcacccggcc
    19621 cacccatgcg ctggacgtgt acgtcgatgc cgttcacccg cagggtcgcc accgtcagcc
    19681 cacctccgcg acggcgagcg accccaccac atagccgacg aggtcaccga cggtcagcgc
    19741 gatgatctcc tcgagaccgc ggtcggccat gaacgcggcg aagttgacgc gctcgccgta
    19801 gaactcgcgc agctgggcgg agagagtgac gaggtcgatg ctctccagct ccaggtcgtc
    19861 gtggaaggac gtgtccaggg tgatctcgga gtcgtcgagc ccgtactcct ccagcacggt
    19921 gcgcaggatg gccgagaggt ccgcgagcac ggtcgcctcg tccggggccg accgcggtgc
    19981 ggggccttcg agttcagtgg tcatcttcgc tctcctgaat cgttgacggc cgtccaggcc
    20041 acgacgtact ccttgccggg ctgtccggac ggccggggga tggtcagcga ggagtgccgc
    20101 acgcggtact cctcgcccgc gacacggacg ctcaccacgg cgccgtccgc cgccgtgatc
    20161 tcgaactgct tgggcgcgcc gcccagtccg gtgccgcgcg ccttcgcgac ggcctccttg
    20221 gcggcccaga agcgggtgaa ccagagtcgt tcgggggctc ctcgcggagc ctgggcgagg
    20281 gctcggagca gctcgcgttc cggcggggcg agggcgacgg cgagggtgcc ctcgggacgg
    20341 tcggtcactt cctcgatgtc gatgccgcag ggcccctcgg tcctggccat cgccacggcg
    20401 ctctcgccgc ggtgggcgat cgagacatgc agggcgggca gggtccggcc gtagccgccg
    20461 gtcacgaagg ggcggcccgt cgggtcgttg ccgacccgca cttcggcggg gaagacgggg
    20521 cccgcgccgc cgtcccacat cagatgccgt acggcgtcct tgacggcgat cctgccgagc
    20581 agccactgcc gtcggccgcg cggtgcgtgc gccgcgtacc gctcgcgctc ctcgcccgcc
    20641 aggatgttcc gcatgatcag ctcgcgggtg gccagatcgg gccactcctc gtggaccagc
    20701 gcccagccgc ccggctgcat ccgggacagg gtgtgccgct cgggctcccg gtccaccgcg
    20761 cggatccgcg ggttgctgtc gaagcggcgg tcctgccagc cggtgaactc cgcccacacc
    20821 cggccccggt acaccagctg catatcggct tcgagcgtgg cgtcggtgac cgaggtgatc
    20881 cggatcaggc actccaaccg ctccccgggg gcggggtgcg ggccgtggaa gcggatctcc
    20941 ttcatgccga ccgggaacac cgtggtgcgc accggcagcc tggacatgat ccagtagccg
    21001 aggagctgtc ccacgttgtc cagcagggcg cccggcgcgg gcgggcagac gagcaccccg
    21061 cgcacatgcc gttcgccgac cgccgtcagt tcgcgcacgc cctggaagcg cggtccgtgg
    21121 aacatccagc ggcgcgagta cagctccgcg gccgtcagct cgggcttctc ctccgccgcg
    21181 gccgggaagg tccagggctc cgccggggcc gggaaggccc agggcgtggc aggcgctgac
    21241 cgcccctggt cggcggcgag ttcgaccacg gcctgcgcgt acgagccgag cgacgcggtg
    21301 acccggtccg ggctctcggg gacgatccgt accgggatgt cgaccgccgg agtggccgtc
    21361 acccactggt gcagccgtac gtcgtggacg gccaccgccc ggcggccggg ggcggcccgt
    21421 tccgcgaagt ccatcagatg ggcgatcacg gtggtgccgg ggaccacggg ccagctgtcg
    21481 gcggggtcgg cccggtcggg ctgcttgaag aagcagtggt cgaggaggta cggcatggtg
    21541 tcgacggaca cgtgaagggt ggtgtcgagg gggcggggcg cggggggctc cgtcgtacga
    21601 gggccgggca ccgcggtcgt acgtgagccg ggcgtggccc gggtgtggtg ggtcgccgcc
    21661 gcggccccgg gcctgcggcg gcccgccgac accacgtccg aggcgagcgc cgtcgcgtcc
    21721 cgcagcagcg cggacaactc agctcccagc aggccctgtt cgccgagggt gccgtggtcg
    21781 ccgtggtcgc cgacgtcccg gggtggtggg gtggccgggg cgcggcgcgg ggccagcgcg
    21841 gcgctcaccc ggtggcgggt ctccgcgtcc agggagacgt tcgctccgcc gaggtccagc
    21901 cggaccggcc ggcggccggt gcgcgcgggt gcggcggccg ccctgcccag cagcggggag
    21961 aggtccgaag ccgccccgtc cgcccacaac gcgctcgcga cacggtggag ttggggcagg
    22021 cccgagcggt tcggggagtg cgcggcgacc acgaggtgcg cacggccgtg cagggtgtcg
    22081 ccgatgagcg agccgaggtg tccggcgccg agctggacga aggcgcggaa gcccgccgcg
    22141 tacatcgtgt ccaccagcgg ccggaagcgg accggctcca gcagatggcg gacgaacagg
    22201 tcgcggatcg ccgccggttc ctccgggtac ggggctacgg tcgtcgcgga ccacagtggc
    22261 agcgcggccg ggtggagggt gtaggtctcg gccgcctttc tgatcgggcc gaggtagggc
    22321 tccagcatcg gggtgtggaa gccggagcgg aacggcagga tctgcgagat cagtgcccgg
    22381 gaccggaaca cgtcgacgag tgcggcgacg gcgggctccg ggccgcagat catcgactgg
    22441 ttgggcgcgt tgtcgtggga gaggaccacg tccgtgcgcc cggccagctc cgtcagcacc
    22501 tgctcggcgg gggcgccgat cgcggcgaag gcgagcccgg gaacgctcag cgcgtcgggg
    22561 tcgaagccgg cgaggaaggc gtcgacctcg tccggtgcgt ggatttcggc ggcggccatc
    22621 gcggtccact cgcccaggct gtgtccggcc agcgcgtcgg gtgcgacgcc gagccggcgc
    22681 agcgccgcgt cgaggagccg gccgagttcg aagacgccgg tgccctgccg gcccacgtcg
    22741 cccacggtgg cgtcggcgac ggcccgcgac cagggcagcc cgaagtgccg ggcgacgtcc
    22801 tcggagttgg gcacgaactc ggcctccagg ccggggaaga cgaaggcgag cttgccgccg
    22861 ccgggcccca gcagcgggct cggcacgaac cacacgtcgc cccggccccg ccacccgtcg
    22921 cccttcgcga ccgccttgcg ggccagcgcc agccgtttcg cggtgggccc gacgacggcg
    22981 agccgcaccg gatcggcggc gggcgccggc gcgcgttcgt cgagaccggc ggcgaggatc
    23041 gcggagtcgt cgcggtccag cagcgcggcc atcgcctcgg gtgtcggcgc ggtcagtcgc
    23101 agcacccgct ccggctcgta gacctgggcc gccctcgtga ccgccacctg ttccagcacc
    23161 acatgcgcgt tgatgccgcc gaaaccgaag gcgttgacgg cggcccggcg cacgggctgc
    23221 cggtcgtcgg cgggccaggg ccgggcggcg ctgatggggg cgaaccgggt gcgggccagc
    23281 gccggatgcg gctcgtcgca gtgcagggtc ggcggcagca ccccgtggtg gacggcgagg
    23341 gcggccttga tcagcccggc gatgcccgcg gcgggcatgg tgtggccgat catcgacttc
    23401 accgagccga tgacggcgcc cggttcgtcg gcggtcgcgt ccttcggtgg cggcccgaac
    23461 acctcggcga gcgtggcgag ttcggcgccg tcgccggccg gggtggcggt gccgtgcgcc
    23521 tccaggagcc cgatcgagcc gggtgccgcc gggtcgagcc cggcggcctg ccaggcttga
    23581 cggaccgcgc ggacctggcc gccggagtcc ggcgccatga gactggtcgt acgtccgtcg
    23641 gaggcgacgc cggtgccggt gatcgcggcg tagatccggt cgccggcgcg ctcggcgtcg
    23701 gcgagccgct tgaggacgac gacgccggtc ccctcgccga tcagcacccc gtccgcgcct
    23761 ttgtggaacg gccggatgcg ctcgctcggc gagagcgcgc cgagttggct gaacacgctc
    23821 cagaaggtga tgtcgtgaca gtggtgcaca ccgcccgcca gcatcacgtc acaccgtccg
    23881 tccgcgagtt cgcgcacggc gtggtcgacg gcgatgagcg aggaggcgca ggcggcgtcc
    23941 acggtgtacg cggggccgcg caggtcgagg cggccggcca gccgggaggc ggcgaggttg
    24001 ggtacgagcc cgatcgacga ctccggcgcc tcggggccga ggcggtcggt gaacgcctgc
    24061 cgtacggcct ccagtcggtc cgcgccgagg tcgggcagca gctcgcccag ggtgcgtacg
    24121 agctggctcg cggtccgcac tcgctggtcg agcctgacca ggccgggggt gaggtagccg
    24181 ccgcggccga gcaccacacc gacccggtgc cggtcggcgg gcagccggtc cgcgccgccc
    24241 gcgtcggcga gggcctgcgc ggccacccgc agcgcgatga gctggtcggg ctcggtggcc
    24301 ggcaccgcgg ccggcatgat cccgaactcg gtgacgtcca cctcggccag ctcgtccacg
    24361 aagccgccgc gccggcagta gacccggtcg gcgcggggct cggcgccggg cgcgtagtgc
    24421 tcgtcggcgt cccagcggcc gggcgggacg tcggtgatgg cgtcgacgcc ggagaccagg
    24481 ttgtgccagt acgtggcgag gtcgggggcg ccggggaaga gcaccgacat gccgacgatg
    24541 gcgatgggtt cggcgcgtcc gggggtggtc atggtcacca gcccgaggcg gtgtacacga
    24601 cggcggtgtc gccctcgggg ccccaggcca gctcgcgcag caggctcatg gtgccctcgt
    24661 cggggtcgat gagccggatg ccgcgggcgg cgtagtgccg catcagctcg ggggtgacca
    24721 tgccgtggtt gccgtcgccg gtcggtgccc acgggcccca gtggacggtc agcccgcggc
    24781 ggcccgcccc ggcgtccgcc cagcgggtgc cgagggtctc cagggcgtcg ttggcggcgg
    24841 cgtagtcgga ctggccgcgg ttgccgaggg tcgcggcgat gctgccgaac agcacggcga
    24901 accgcggccc gtccggcaac tcgctgatcg cgtccagcag ttcacgggcg ccgtcggcct
    24961 tcgtacggaa cacccggtcg tacgaccgcg ggcttttctc cgcgatcagc ttgtcctcga
    25021 tcacgcccgc cgcgtagacg acggcgtcga gtctgccgtg ctcggcgtgg atctccttca
    25081 ccgcccggcg cacggcgtcg ccgtccagcg cgtccacggt gcggtagcgg acctcggagc
    25141 cgagtgcggc gagccggcgc agcgtgccac gcacctcgcg ctcggcctgg atccggccga
    25201 tcgcccgttc gatctcggcg ggcacccgca ggccgcccgc gatgagcgcg gcgcgcagtt
    25261 cgcccgtggt gaccgcgggg gcgagggcgg ggtcctcggc gccctcgggc agggcggtgc
    25321 ggccgaacag ttcgatccgg cagcggcagg cggcggccag ggtcgcggcg aaccgggcgg
    25381 tgatcccgcg ggcgccgccc accagcagca cgaccgagtc ggtgtcgagg ccgagcgcgg
    25441 cggcctcggc cgcgccgtca ccggccgggc ccgcgcccgt tccgccgagc aggcccaggc
    25501 cctcctcggc catgcgcagt ccgcgacggg tgcccgggga acgtagcacc accggctccc
    25561 ggtcgtcggc ggtgagttcg gcgacgagac cggcggcgat gtcctcgggc gcggtgccgg
    25621 gggcgtgctc gacgacccgg gccaccgtgt cggggtactc gcgcgccacg gagcggaaga
    25681 agccgcgcag tccggcggag gtgcctgagg ccagcaccca gcgtgggttg cccgccagca
    25741 cctgtcggta gacggggaag gtgtccggca ggacgggtgg ggcgtccggc gcgacgaggt
    25801 ggatgaggcc gtcgaacttc tcgtcggccg ggggctcgtc ggcggtgagc gcgtgggcgc
    25861 cgtgcgcggt gaggcgggcg gtcagcgcgt cggcgacggg tccggtgccg aggagcagga
    25921 agttccggcc cgtcagccgg tcgccggtgg gcgcgggctc ggcgggggcg aggtcgaact
    25981 cccgcatcac caggcgcttg ggcgccacga ccaagggctc tgcgccggcc ggggcggact
    26041 gcggggtggc tgccggggtg acttccgggg ccctggcctc ggctgcctcc cctcgggcac
    26101 ccgccaccag ctcggcgatg ctcgcggcgg tgcgtgcctt cgccagttct tccacgtcgg
    26161 tgtcggcggt ggtggtgagg ccgagtcggg cggcgagttc gccggcgatt tcggctcgtt
    26221 tgatggagtc gacgctgagg tcggcttcga ggtcgaggtc gggttcgatc atgtcgacgg
    26281 ggtagccggt gcgttcgccg atcacgtcga gcacgagtgc gaggacggac tcggcggtcg
    26341 gtgcggggcc cgcggcggga gcgggggcct gggcagccgg ggccggggtg ggaacggcgc
    26401 ccggtccggt gacccgctcg accagcgcgg tgatggcggc ggcggtgcgt gccttggcga
    26461 gttcttccac gtcggtgtcg gcggtggtgg tgaggccgag tcgggcggcg agttcgccgg
    26521 cgatttcggc tcgtttgatg gagtcgacgc tgaggtcggc ttcgaggtcg aggtcgggtt
    26581 cgatcatgtc gacggggtag ccggtgcgtt cgccgatcac gtcgagtacg accgagagca
    26641 ccgagccccc ggcgggctcg gccacggcag ccacggcagc cggtgcggcg ggcggcgcgg
    26701 tcacggtgac gggggcgtcg gcgtacgtga ccggggcgtc ggcgtacgtg gccggggcgg
    26761 cggccggggc cgggggccgt accgccggat ccgcaccgag ataccccagc atcacatccc
    26821 gctgagccgc gatcatctcc cggctcgtcc gcaggaactc actgatcagg gcctcggagc
    26881 cggtggctgc caccggtccg gccgaggtgc tgtgggtcac gagggcctcc gggacgcgct
    26941 cggcgggatg gagtgcggcg gcggggatcg cgccgtccgc cgtgcggatc agatggccgt
    27001 cgacggtcca cgcggcgcgc acccggcgag gtgcccgggc ggcgtcgacc gcgccccggc
    27061 cctggaagag ccacgaggtc ctgacgtcca caccggcgac ggccagttgg gcgagcgcgg
    27121 cgaggaatcc gacgagaccg gtgtgccggc ccttctccag ggcgaccgtg cggtgcggcc
    27181 ggtcgccgag gaccgtgccc accagccggg tcagcaccga gccggggccg gcctcgacga
    27241 agacccgggc cccggcctcg tacatcgcct cgatctggtc ggcgaaccgg accggtgcgc
    27301 cgatctgggc ggcgagttcg gcccggatcg cctcggggct ctccgggtag cgggcggccg
    27361 tacggttcga ccagaccggg aagtcggtcg cgccgaccgg gacgtcggcg agcaccttcg
    27421 cgaaggcctc gcccgccgcc gcgaccagcg ggctgtggaa cgcgcaggcg accgggatgc
    27481 gcttggcgcc caggccctgg gcgcgcagcc gctcgacggc ggtgagcacg tcgtccgtgg
    27541 ggcccgaaat caccgtctga cggggcgagt tacggttcgc cgtcaccact gagccgtcga
    27601 gtcccgccgc cgccagggcc gccgcgacct ccggttcgcc cgcggcgacg gctgccatgg
    27661 tgccgggatc accgtcgccg gcggcgccca ggacggcggc ggcccggccg cggctggtcc
    27721 gcaccagcgc gtcgggggtg agggcgcccg ccgcggccag tgcggccagc tctccgtagc
    27781 tgtgccccgc ggccatcgcc gggcgtatcc cggccctggt gaggagctgg aacgcggcga
    27841 gtccggtgag cccgagcgcg ggctgtgcga cggtggtgtc ggtgatccgc tcctgctgct
    27901 ccttgcggct cgcctcgtcg aaagccgtcg gcgggaagag gacgcgggcc gtcgtctcgt
    27961 cgagccgcag atggcgctgg agttcgggga aggccacgaa cagctccgcg aacatccccg
    28021 gccgctggct gccctggccc gggaagagca gcgccacctc gcccgtctcc gtgtcgtcgg
    28081 cggtgaacag gccctccttc ggggcgtgtt cacccgcgac ggcccggcgc agcagcgccg
    28141 ccagctcctc ggccgactcg gccacgaggg cgatccaggt ccgggcgcca cgcgtgccgg
    28201 cggactccgc gcggcgggac gcgccgagcg cgaagtcccg cagccgccac ggctcgtggg
    28261 gtccggggtc cgcctcgacg agggcgagca gctcggtggc ggcgcgcacg gccgccgccc
    28321 ggtccgcgcc ccggaaggtg aacagctcgg cgggccactg ctgggcggcg gtgaccggcg
    28381 gtggaccgtc ctcgtaggcc cgcagcacga catggaagtt ggtgccgccg aagccgaagg
    28441 cgctgactcc ggcgacccgt tcggccggcg cggcgggcca ggggcgggcc tcggtgtgga
    28501 aggcgaacgg gctgctctgc gcgtcccagg ccgggttcgg ttcggcgagg tgcagggtcg
    28561 gcggcttcac tccggtgtgg agggcgagcg aggccttgat cagtccggcc agcccggccg
    28621 cgcacttggt gtgcccgatc tgcgacttga ccgagccgag cgcacacctg ccgggctcgg
    28681 cgccggcctc ctcgaacacc cgggtgagcg agccgagttc ggtgcggtcg ccgacgacgg
    28741 tgccggtgcc gtgcgcctcc acgagcccga cctcggcggg cgagacgccc gcgttgcggt
    28801 aggcccgggt cagcgcgttg tactgcccct cgggccgggg cgcggtcagg cccagcgccc
    28861 ggccgtcact ggcgctgccg acgcccttga tgaccgcgta gatccggtcg ccgtcgcgct
    28921 cggcgtcggc gagccgcttg aggacgacgc agccgacgcc ctcgccgagc gcgatgccgt
    28981 cggcggcgct gtcgaagggc gcggagcggc cggagggcga gagggcgtgg gcggaggcga
    29041 agagcaggta gtcgttgatg ccgttgtgca gatcggcgcc gccgcacagc accaagtcgc
    29101 tggtaccgcc gctcagttcc ttgcacgcca cgtcgacggc ggtgagggag gaggcgcagg
    29161 cggcgtcgac ggtgtagttg gcgccgccga ggtcgaggcg gttggcgatc cggcccgcga
    29221 tgacgttggc gaggatgccg gggaaggagt cctcggtgag ccgcggcagc tgctccgcca
    29281 gcgcgggcgg cagagtgccg agataggcgg gcagtacgga ccgcagcgtc atggcgttcg
    29341 acaggtcact gcccgcctcc gcgccgaaca ccaccgacgc gcgggcccgg tcgaaggacc
    29401 ggctcccgta accggagtcc tccagggccc ggcgcgcggc ctccagggcc agcagctgca
    29461 ccggctcgat ggcgggcagt gaggcgggtg gaatcccgta ccgcagcggc tcgaacggga
    29521 tctcggggag gaagccgccc cagcgggacg gggtcttctc cccggcgccg ttcaggtcgt
    29581 ggtagaggtc ggcgtcccag cgggtcgcgg gcacctccgt gacggcgtcc gcaccggcga
    29641 gcacgttcgc ccagaaggcg gcgaggtcgg gggcaccggg gaacatgcag gccatgccga
    29701 cgacggcgat gtccagcggc tcgggggagg cggcgatggc cggttcctcg atgccgaggg
    29761 cgtccagccg ggccgccagg aagccggccg ccccggtggt caccgaggcg tgcaggtcgg
    29821 cgacggtggt gatggccgag cgcaggacgg cgacctctcc ggccatgaac atgccctcgg
    29881 cgagctgtct ctcctcaccg acctcgtgaa gttcgccccc ggcccgctcc aggcccttgc
    29941 tggccagccg caaccggccg acgttgagct gctccagccg ctcccaggcc tcccggccgg
    30001 gtacgtcgcg ggcggccagc tcctccttga cggcggcgaa ctcgtcggtg aacgggctgc
    30061 ggacacagcg ggtggcgtgc ccgggagcgg tctccaggag atcggtgcgc tcggctgcga
    30121 tcacctgccg ctggaacagg ggcagtaccg cgcccgcgct cacggcctcc tcggtgaaca
    30181 gatacgccgt gcccatcagt acgcccacgg cggcaccccg ggcgctcagc ggcgcggcga
    30241 gggcggtcac catggcggcg gaccgctcgt cgtgcacccc gcccgcgaac agcagctgca
    30301 actccgcggc cgtaccgttc ttggcgcccg ccaggaagtc gtcgagcacg cagagctgcg
    30361 cctcccacag cgggaagctg ccccgcgggc cgacatggcc accgcactcg gcgccctcga
    30421 agacgaactt gcgcgcgccc gcctccagga actgcttcag gagccccggc gacggcacgt
    30481 gcaggaaggt ggagatgccc accgcctcca gtgcggccgc ctgcgcggga cggccgcccg
    30541 cgatgatcgc gtgggagggg cggatctccc gtacgacctc cagctgggcg gccttgatct
    30601 cctcgtcggc gaatccgagg accccgactc cccagggcgc gtgcccgagg gcgtccctgg
    30661 tccgctccag gacggtgcgg gtctgctcgg cgccggagag cgcgagcgcg atgaagggca
    30721 gcgctccgtg gccgctcacc tcggcggcga acgcggcctg gtcgctcacc cgggtcatcg
    30781 gcccctggac gaccggcagt tcggtcccga gcgcacggct gcccgcgctg tcggggccga
    30841 gggcgggacc cgcgctcttg agggcgtcga ggacggcgtc acgtacgccc cggaccgccg
    30901 cgtggacggt gccccagcgc tcatggaagc gtgccgcgag gaaaccgtcc tgaccgatct
    30961 cgggcgccgg ggcaccgtcc ggggcacccc ggcgccgtac gacacggcgg ccgttctcca
    31021 cggtggtctc ggagccgtcg agcccggtga ggagtacgga ggtgccggcg ggcagtccgg
    31081 cctcggcctc ggtgagcagg gcgagctggg tgtccaggac gacaccggca ccgccgcccg
    31141 cgacgacggc cgccgcggtg tgcgggcccg cgccgccgca ggcccagacc ggcaggtcca
    31201 actcccggtc ggcgagcagc tgttgcacca gcacgaacgt gcccagttcg cccacggggc
    31261 cgcctgcctc gtggccccgg gcgatcagtc cgtgcgcccc ggccgatagg gcccgtaagg
    31321 cctgctcatg gccggtcacc tcgacgagca cgcggtggcc ggggaagtcg cccggggtgc
    31381 acgaggcgtc gctggtcagc aggacggtgt gcacgcgggc ggggaggtcc cgcgcgggaa
    31441 aggcatcgtt gtcggagagc cgtacgccga agccggcggc cgaccattcc tcggcgagcg
    31501 cgagttccgc cgccgcccgg cgcccacccg aggtgaggtc gagcacgccg agaccgccgg
    31561 cccgtacggc ggccgcggtg acccgtgccg aggggacggc gagcgggctc acggcgatga
    31621 cgatgtcctc gacagcaaac agcccggaag tatcgaaatt cgacacaggc acgcgaacgc
    31681 tccaaatcac acgagagtga ggaatggtgg gggagagcgc ttgtgcttca caaggcactg
    31741 cgaagcacgc tcatggttat tgcgcatcct cgcgaaagtc aaactctcaa tgagacggtc
    31801 cttgccggat gtaacactgc cgacacggct gcatcggatt cctgtgtgaa cgggcgacag
    31861 cggcctgacc cgagggcggt tgagggggcg ccgaccgcag gccgcgcgcg tcctccgccc
    31921 caactcatcc tgcgcgtacg tgtcctgacg gcgcgtcagg atggtgtccc gattggatca
    31981 agcggaaacg cattgtttcc ccaggtgtaa attgaatcct taaacagttc cctttcatat
    32041 aatcaaaatt cacgctgggc aaaagggttg gattcggcac ttgagtgtga atagccacga
    32101 ttcgtactcg ccggtagatg gctcgtttag gacgcacgtt ccatgggatc aagcccgctc
    32161 ggtagcgcct tccggccgcg tggggcggtc gggccgtggc cgaatccaaa aggtctcggg
    32221 gcggtggcgc aggaggcgta cggggctttg cggcagggga aggggccgca ggatgtcttc
    32281 ggcatcgcga ggcgggccga tcagatcaac aggcgttcgt cgctgtcctg gtcgccctgg
    32341 tcgtcccgcg tcggctgcgt gcccgaggca tcagcaccgg gtgttcgccg aattccggcc
    32401 aggaaccggc ggacttcact ggatcagcgg cagcgcgggg aaggtgtggc gctcccagag
    32461 gcgccgggag gtttcctcgg ggtaggggat gacctctggg gccgcgtcga ggacttggac
    32521 cagccgccgc tcggtgtcgt acgtgggcca gccggggtcg cccgtccgtg cgaacgccgt
    32581 ccaggacgcc cggaaacggg atgacagcgc ctcggcctcc ggtgagggtt ccgtaccggc
    32641 gaacagcagg ctgccgaggt cggcgtcgaa cgtgccgaac agcagcggga tgtccaggcc
    32701 gtggcaggcg cccagtacgc cgccgttgcc cggggccggc caggtcagct cgtagacgtg
    32761 ggcgcgtccg ccgccggtga gctgcgcctc ggccaggtgc agtgagggca tgtggaacag
    32821 ccagtcggac atgacgcgtt cgtacagctc gcccggcgag gcgtcgggga agccggtgcg
    32881 gtaggcctgt tcggcgtccg gtccgggtcc gaacctgcgc agtgctgccc gcgcctcccc
    32941 gtcggtgatc tttccgagct gtccggagag gaggacgaac agccggaatt cctcgctgtt
    33001 gtgaccgacg atcagttcga cgtcccgggc ggtgccggcc gccagcgcct gccagggggt
    33061 ggtgggcagg acctcgccgt cgacgacggg ggagaagggg gtcagggtgt ggacgaccgg
    33121 cccccaccgg tcctcgtact ggcgcatcgt ggccgccaac gcctcgcctg cggcgggtag
    33181 ttgacgtggg tcgacggtgg acagatcggc ggccgtgggg cgcaggcccg cttcggcggc
    33241 gatcgcggcc gcgatgtcct tggccagttc gtcggagaag tacgtgcccg gcacgctctg
    33301 ggcgatggcc cgccggaaga ggccggacgc gctcggcatg gccagcagcg aggcgattga
    33361 tccggcgccg gccgactccc cgaagacggt gacccggccg gggtcgccgc cgaacgccgt
    33421 gatgttctcc cgtacccatt ccagggccgc gacctggtcg agcagaccgc ggttggcggg
    33481 agcgccgtcg acccgggcga agccctcgat gccgacacgg tagttgaggg tgaccacgac
    33541 gacgtcgccg tcgcgggcga tgcggcgagc gtcgtagccg gggctgccgg agtggccgag
    33601 cttgtaggca ccgccgtaga tccacaccat caccgggcgg cgggcaccag ggtccgggtc
    33661 gggtgtccag acgttgaccg tcagccagtc gtcgcccgtg ggcgcgtcca gcagggcggc
    33721 gcggccctgg atccccgtct cctggggcgg cggcggaccg aaggcgaacg cgtcccgtgt
    33781 cccgtcccag gcgcgtaccg ggcgcggcgc ggcgaaccgc gcgtccccca cgggcggttc
    33841 ggcgaacggg acaccgcgga agaccgccag gccgccctcc aggcggccgc gcaccgtacc
    33901 ggcggcggtg gggaccacgg gctcggcgga ccccggcgcc gacgcgcggg aatcggctgt
    33961 cgtcatcgtt gactcctcag tggttgccgg tggagcgacc tgtcagtggc tgctggtgga
    34021 gcgacctgtc agtggctgct ggtggagcga cctgtcagtg gctgctggtg gaacgacatg
    34081 gtgcacccgc gggcccggac cgctcgacct cacccccgcc gagtactggc tcctgggccg
    34141 tctaccggcc aacgcggagc gtgtgctgtc gacagacccc tgccgggtac cgcgcggcgc
    34201 cgctgaggtc cggcatgccg acggggccct ctcaggacct cgcctcatac gggccgcccc
    34261 ggaagtacag gcttccgtac ggtcggggac ggtcaccgcg ctcatgcgcg gcgtcggagc
    34321 ggtcggcagg tgccgaccgc tcggccagag cgcgcagcgt ctccagaccg gccaggacct
    34381 cagagcgctg gtccgccctc ttcatccacg ccggcagccg cgcgaacatg gcccgcgtcg
    34441 gccgcacccc gccacgctcg cgcacccggg cgcccacgta ggccgacaac tcgtcgacat
    34501 gctcctcgtt gtaggcccac aggatccggc cgacgcaacg ggtctgcagc cacagcggcc
    34561 gccggaaaaa cggatcctca ctcccgcccg gcaccgcgcc gaccagcccc gcaccacgca
    34621 tctcgggttc ccggtcggcg acggttccgc acccaccgca agccagacgg cgtggctgga
    34681 acaacagctc gctgaagtac ctgggcgcgg gaagaccagg ccggggaacc acgagcgcac
    34741 ggccgccgca tcgtggacag accaccagca tgcggccggt gaactgggcc aactggcggc
    34801 cggggtcgta gtggcgggca ggaccggtac ccggctcgga atccatgacg gacaccctcg
    34861 caggttcgcg acgccgcccg cgaccgggtt ctcgcgcgcc ctggccgccc acgccgtcct
    34921 cgccggcgcg gaagccgggg ccaaggagtt catgacgcgg ccgcgtcgag gccggacggt
    34981 ggatcggcgc ccgctttcgg atgacgtcac agcctgtcgc cggggcggac cggccggcat
    35041 gcctgacgat cgcagtcggc cggtcatccc tgcccgcccc tcgtccgccc ggaggcagct
    35101 gtgcacatcc tgctcgtggc cagcgcgttc aacagcctca cccagcgcgc ccatgccgaa
    35161 ctgcgggacc gtggccacac cgtggcggtg gaactcgccc tgcccggcgg ctcgttgccg
    35221 gaggccgtgc ggcggcacgc cccgcagctc atcctggcgc cgatgctgaa gaccgcgatc
    35281 cccagggagg tgtggtcggc gcacacgtgc ctcgtcgtcc atccggggcc cgtgggtgac
    35341 cgcggaccgt cctctctcga ctgggcgatc cacgagggcg ccgaccagtg gggtgtgacg
    35401 gtccttcagg ccgacgagga aatggacgcc ggtgacgtgt gggcgtccgt tccgtgcctg
    35461 cttcctccgg tgtccaagag cgacctgtac cggggcgagg tcgccgacgc cgcgctcgcg
    35521 gccgtcctgc tcgccgtgga acgctttgcc accggaacct tcgttccgcg caaacaagcc
    35581 gaccaagccg gccaaggcgg cggccaaggt ggtggcgaag ccgaccaagt cggccaaagc
    35641 gtggcacgcc cggaaggcgc ccacccgcgc acccgtccgt acctcgacca gagcgtccga
    35701 cggatcgact gggccgagga ctccacacgg accgtcgtac gcaagctgcg ggccgcggac
    35761 tcccagcccg gtgtgctgga cgtgctgctc ggcgacgcgt ggtatctcca cggcggccac
    35821 ccggagagcg tgttgcgtgg ccaccccggc gagctgctgg ccaccagggc cggggcgatc
    35881 tgccgggcga cgaaggacgg cgccgtatgg atccccgagc tgaggccccg gcgtgcgccc
    35941 gggcagccgc cgacgttcaa actgcccgcc gtacaggccc tcggcgaccg gcttcctcca
    36001 ctgcgagagc acaccgtgcc cctgttcccg gacgcgcggc accctacgtg gacggacatc
    36061 cgctaccggg aggaggggaa cgcgggtttc ctctcgttct ccttccccgg cggcgcgatg
    36121 agcaccgcgc agtgccgacg cctgctggac gcctaccggg acgcgtgcac gcgacccaca
    36181 tcggtgctgg tgctgggcgg cgaacgggac ttcttctcca acgggatcca cctcaatgtc
    36241 atcgaggccg cggacgaccc cggtgccgag tcctgggcga acatcaacgc catcgacgac
    36301 ctcgtcgagg cggtcctgac gacgacggac cggctggtgg tctcggccgt cgcgggcaac
    36361 gccgcggccg gcggggtgat gctcgccctg gcggccgacg aggtgtggtg ccgcgcggga
    36421 gccgtgctga acccgcacta ccgtctgatg ggcctgtacg gctcggagta ctggacgtac
    36481 accctgccgc gcagggtggg gcccgcggcg gccgaacgac tcatgcgcga ggcgctgccg
    36541 gtgagcgcgg caagcgcccg gcgtacggga ctcgtcgacc gggtgatgga gtgcggcccg
    36601 caggagttcg ccgcggaggt cggccgcctg gcggctcgcc tggcggcgct gccgggaacc
    36661 gcgtcacgga tcaccgcgaa gaagagggag ctggaccggc aggagagcgt catcccgccg
    36721 gccgctttcc gcgagcagga gctggcccgg atgcgccgga ccttcctgga cccggacgcc
    36781 ccgtatcacg cgctgcgtcg cgcgttcgtc cgcaaggagc ggcctcggcg caccccgccg
    36841 catctcagcc ccgccgcggt tgcgccatcg ggccagatcc cctccgaggc tcacgtcact
    36901 ggaacggccc cccacggcgt ctcaccgcga ccggatggct ggtacgaaga aagctgacgg
    36961 tcgaaatacg gactttcacc ccatacctcc ctaggaggcg gtcccatgac tgcggcaacg
    37021 ccggacacgg tcggcgctgc ggacgccgga ggtgcgcccg ccgacgagac acccacgatc
    37081 cacattctct ggatcaacgc agggctgagc tgtgacggcg actcggtcgc gctgacggcg
    37141 gccatgcagc cgagcatcga ggaaatcgtg ctcggcgttc tgccaggtct gccgaagatc
    37201 gccgtccatt ggccgctcat cgacttcgag tgtggtccgg tcggtggctc ggacacgttc
    37261 atcgagtggt tcttcaaggg ggagcggggc gagatcgacc cgttcgtgct ggtggtcgag
    37321 gggtccatcc ccaatgagtc gatcaagccg gagggctact ggtgcggttt cggggacaac
    37381 ccggagaccg gccagccgat caccaccagc gagtggatcg accggctcgc gcccaaggcg
    37441 ctcgccgtcg tcgccatcgg cacctgcgcc acctacggtg gcatccacgc catggccggc
    37501 aacccgaccg gggcgatggg cgtgcccgac tacctcggct gggactggaa gtcgcaggcc
    37561 ggcatcccca tcgtgtgcgt ccccggctgt ccgatccagc ccgacaactt ctccgagacg
    37621 ctcacctatc tgctctatca ggcggccggc gccgccccga tgattccgct ggacgacaag
    37681 ctgcgtccga cctggctctt cggggccacc gtgcacgagg gctgtgaccg tgcgggctat
    37741 tacgaacagg gccagttcgc cctgacgtac gactctccga agtgcctggt caagctcggc
    37801 tgctggggcc ccgtcgtcaa gtgcaacgtg cccaagcgcg gctggatgaa cggaatcggc
    37861 ggctgcccga acgtcggcgg tatctgcatc gcctgcacca tgcccggctt ccccgacaag
    37921 ttcatgccct tcatggacga accccccggc gcgaaggtgt cgagcagcgc cagcggcgcc
    37981 tatggcgcgg tggtccgcaa gctgaggacc ctcacggccc ggaccgtgga caaggagccc
    38041 aagtggcgcc acaccggaga ccggatcacc accgggtacc ggccaccgtg gtgaagcccc
    38101 gccgcacctg acccgccccc gagattcgtg caactcccca cacttcccgc gcaacgaagg
    38161 gcacggcaca aacgatggca tcgacgacga aggcggccgg cgacggcagt ggcctggtgg
    38221 agatggcctg ggacccgatc acacggatcg tgggcagcct gggcatccac accaagatcg
    38281 acttcaagca gaagcgggtc gcggagtgct acagcacctc gtcggtcttc cgcggctaca
    38341 gcgtcttcat gcgcggcaag gacccccgcg acgcgcactt catcaccagc cgtatctgcg
    38401 ggatctgcgg ggacaaccac gccacctgct cggtgtacgc gcagaacatg gcctacggcg
    38461 tgaagccccc gcacctcggt gaatggatca tcaacctcgg cgagtccgcg gagtacatgt
    38521 tcgaccacaa catcttccag gagaacctgg tgggggtcga ctactgcgaa aagatggtca
    38581 aggagaccaa ccccggtgtc ctcgaactcg ccgagcgcac cgaagcgccg cacgccgggg
    38641 accacggcta ccgcacgatc gccgacatca tgcggtcgct gaaccccatc gagggcgact
    38701 tctaccgcga agccctacag gtgagccgct acacccggga gatgttctgc ctcatggagg
    38761 gacgccacgt gcatccctcc acgctctacc cgggcggcgt cggcacgatc gcctccgtgc
    38821 agctcttcac ggactacctc agccgcctga tgcgctacgt ggagttcatg aagcgcgtcg
    38881 tgcccctgca cgacgacctg ttcgacttct tctacgaggc actgcccggg tacgaggaag
    38941 tggggcgccg gcgcgttctg ctcggctgct ggggagcgct caacgacccc gagtactgcg
    39001 acttcaccta cgccaacatg acggactggg gccgacgcat gttcgtcacc cccgggatca
    39061 tcgtcgacgg caaactcgtc accaacgacc tcaccgagat caacctcggc atccgcatcc
    39121 tgctgggcag ttcctactac gaggactggc aggggcagga acagttcgtc acccatgacc
    39181 ccctcgggaa cccggtggac ccgcggcacc cgtggaacca gcacaccatc ccggccccgc
    39241 agaagcggaa cttcgacgac aagtacagct gggtcatgtc gccccggtgg ttcgacggca
    39301 aggaccacct ggccctggac accggtggcg gccccatcgc ccgcctgtgg tccaccgccc
    39361 tgtccggcct cgtcgacacc ggctacgtga aggccaccgg ccacagcgtg gtcatcaacc
    39421 tgccgcgcac catgaccaag cccgagacca ccttcgaatg gaagattccg cgctggagca
    39481 acgcgctgga acgcaatcgc gcgcgcacct acttccaggc ctacaccgcc gccgtcgcac
    39541 tccacttcgc ggagaaggga ctggaggagg tccgggccgg acgcacccag acctgggaga
    39601 agttcgaggt gccggacgag agcatcggcg tcggattcac cgaggcggta cgcggcgtcc
    39661 tctcccacca catggtgatc cgcgacggca agatcgccaa ctaccacccg tacccgccca
    39721 ccccctggaa cgccagcacc agggactcct tcggcacgcc cggcccgtac gaggacgccg
    39781 tgcagaacac gccgatcttc gaggagaaca cgccggagaa cttcaagggc atcgacatca
    39841 tgcgcgccgt gcgcagcttc gacccctgtc tgccctgcgg tgtccacatg tacgtcggcg
    39901 gaggaaagac ggtgcagaag atgcatgtgc ccaccgggct gagcggactg ggcggatgag
    39961 cgcggtatcg gcgacgaacc gcgtgaccgc cgagcagacc gggcgccgta tcgaggacgt
    40021 actggaccgg ctggccgcca ccggcgaccc ggcggccggc gcggcggccg aagaactcgt
    40081 ccggaccctc atggagttct acggctcagg cctggcccgc atcctccacc tgctgtcctc
    40141 cgcccccggc ggtccacggc ccccgggcga ccccctggcg gccctgctcg gcgacgaact
    40201 ggtcgcgagc ctgctcgtcc tgcacgacct ccaccccgag gaccgggacg tccggatcgc
    40261 cagggccctc gacagcgtcc gcgaccaggc tctggaagtg gtggccttcg acgagacgag
    40321 cgggaccctg cggctgcgga cccgggcggg cgcgggctgc ggctgcgccg gcaccggcac
    40381 ggccgccgtc caggccgccg aggacgcgct cgcctgcttc gcaccggagg tcacggccgt
    40441 cgagatgcag cccgccgccg cccccgggga gcccgccctg ctccagatcg gcaccggccc
    40501 gaattccggc gccgtggccc gtccggcagc ggcgaagacc gcatgagcgg gacccggaca
    40561 cccgcccggg cccccggccc gggcccgcgc gcccccggcc tgcgcaggtt cctgacggag
    40621 cgtccacccc gccaggagcg gtgcgagctg tgcgcggtgg cggtggccga ggccgaccac
    40681 cgccacctgg tcgacatcga gaaacgggcc ctcgtctgcg cctgcgtctc ctgcgcactg
    40741 ctgatggaac agccgggagc cgccgcgggc cgcttccgtg ccgtcccgaa ccggtacctc
    40801 accgacccgg accaccgcct cgacgacggt gcgtgggagg cgctccagat cccggtcggt
    40861 gtcgccttct tcttccgcaa cgcggcgctg gaccggctgg tcgccctcta cccgagcccg
    40921 gccggagcca ccgagagcga actcgaaccg tccgcctgga cgacggtgct cggtgacagc
    40981 cgcctcgccg tgctgctcga acccgatgtg gaggcactgc tgctgcgccg caccgacggc
    41041 cggtgcgagt gctacctcgt accgatcgac atctgctacg aactggtcgg ccgtatgcgc
    41101 ctgctgtggc agggcttcga cggcggcgcc gaggcccggg ccgccctgga gacgttcttc
    41161 gagcacgtcg tgcgacgcgc caagcccgta cgcgaggtgg gcaggccgtg acggagttct
    41221 ccttcgagtg caccggcgta cgcgccgacc ggtacgccgc cggaccgacc ctcctgttcc
    41281 ggctgcgcgt caccgcggcc gacaacgccc gcgtgcacgc actcgcgctg cgctgccaga
    41341 tccgtatcga acccgcccgg cgcggctatg agtccgccga ggccgacggt ctcgccgacc
    41401 tcttcggcga gcgctcacgc tggggcaaca ccctccagcc ggtgcagttc gcgcaggtct
    41461 ccctgatggt ccccggcttc accggagaga ccgaagtcga cctcgtcgtg ccctgcacct
    41521 acgacatgga catcgccgcg acgcgctatc tggccgcgct caagggcggc gaggttccgc
    41581 tgctgatgct cttctccggc acggcgttca ccggagccgc cgggttccgg gtcgagccgg
    41641 ttccgtggga ccgggaggcg gccttccgga tgccggtctc ggcctggcgg gagatggtcg
    41701 agcagcactt ccccggctgc ggctggatcc ggctgccccg cgacaccatg gacgccctgc
    41761 tcgcctaccg ctcacagcgg gcgctgccct cctgggaggc gaccgtgcgg gctcttctcg
    41821 aggagaaggg caccacggac ccgccccgga aggaccccta cctcgcgctc acccgaacga
    41881 ccggagggac ggatctgtga ccgtgaccgc gttcgccgcg cagaccgagg cgcggttcgc
    41941 cctcgcccgg caggtggccg acgccgttct cttcgagggc tatgtgctct acccgtaccg
    42001 ggcctcggcg gccaagaacc ggctgcgctg gcagttcggg gtgctggtac cgcccgagtg
    42061 gggtgccgac tgcgaagagc acgacttcca gcacaccgaa tgcctgatgg aaccgaaggc
    42121 gggcgcgacg ctgtcggtcg agctgcgctt cctgcgcgcc cggcggcgga ccgtgcagcg
    42181 gatccgcccg gacggcggct tcgacacggt tcccgaactc cggctcgacg accgggtcct
    42241 ggttccctgg gacgagggag ccgaggagcg cgtcgaagtg gtcgcggcgg tggacgagct
    42301 cctgggcgac ggtgtcacgg ttcccttcac ccgccccgcc ctggaggagg acgagccggt
    42361 tctcgacgcg acgggccggc ccgtcggccg cctggtccgg cgctgcgagg agatcagcgg
    42421 cgccgtgcgg ctgtccgccc gcgaactcga cgggccctac cggacgctgc ggctgaccgc
    42481 cgtggtcgag aacacctcca cctggacacc tccacagggc cgcagcgccg accgggacgc
    42541 ggcgctgccg cactccctgg tggccacgca cctcctcatg gccctcagcg ccggatcgtt
    42601 cctgtcgatg accgatccgc ccgagtgggc gaagggcgcg atcgccacct gccgcaacct
    42661 gcacacctgg cccgtactcg ccggcgaacc cggccgcgcg gacctggtgc tgtcctcgcc
    42721 gatcatcctg gaggaccacc cggcgatcgc tccggaaagc ccgggagcgc tctacgacgc
    42781 caccgagatc gacgagatcc tcgcgctgcg gaccgccgcc ctcaccgacg aggagaagcg
    42841 cgaggcccgg ggcaccgacg agcgggcggc cgccgtgatc gacctcgcgg actcgatgcc
    42901 ggccgaggtt ctcgaacgcc tgcacggggc ggtgcggagc ctgcgtgagg tgaccgcccc
    42961 gccgagcgcc gccgggccgg ccgccggagg gttcccggac gagtacgggg tgcggcgccc
    43021 ggacaccccg tggtgggacc cggcgagcga ggccggcttc gaccctcagc acgaccgggt
    43081 cgtcgtggac ggccgctcgt tgggcgccgg aagccgcgta ctgctgcgac cgggcctgcg
    43141 ccgcaccgac gcacaggacc tgttcctcca gggccgcagc gcgcaggtcg aggcggttct
    43201 gcacgacgtc gacggcgggg tgcacctggc ggtgacggtc gagggcgatc cgggcgccga
    43261 catccgccgt gagcaggggc ggttcctgta cttccagccc gacgaggtca caccgctgga
    43321 ggacgacgca tgagcggtcc ccgggaggtg cccccaagga ccctcgtcgc cggcatcggg
    43381 aacatcttcc tcggggacga cggcttcggt gtggagaccg cgcgcaggct cgccgagcgg
    43441 caactgcccg cacacatcga ggtcgtggac atcggtgtgc gcggggtgca cctcgcctat
    43501 cagctcctgg acggctacga caccctcatc ctcgtggacg ccacggcacg cggcgaagcc
    43561 cccggcacgc tgtacctgat cgagcacgac agccccggtg gaggcgagcc cgagggagcc
    43621 cccgtgctcg acggccaccg gatgaccccc gacaccgtcc tggcactgct ggacacgctc
    43681 tgtgccggta ccggcggaca gccgccgcgg cgcaccctga tcgtcggctg cgaaccggcc
    43741 tcggtggagg agggcatcgg tctcagcccg ccggtgtccg acgccgtacc ggaggccgtc
    43801 cggctgatcg acgagttgct acgggccgac gagccgggag agtccgcgcc gcgggccacg
    43861 gccgacggag ccgcgaagtg aggagagacg cgatgaagaa gaccatcatc tgcggcgtgg
    43921 ccggcgccgt cctggccgcg ctcgtcaggc tggcacttcc cgacgtcaga cgctactggc
    43981 ggatccgcag gatgtgacac gccgcccgtt cgagcgcgcc gcgccgttgc ggcgaacggc
    44041 gtaccccggc ggccgacgac ggcgtgccgg gctgtcgagc cccgacagcc cgcctctaat
    44101 ggaggccggc gggccgagca cggcacacct tcccgcgcgg accgggcggc ccggtgccgc
    44161 ccgcgacagc ggtggtggaa gccggcccct gggaggacag agaccgatgc acgagatgtc
    44221 cgtcgcgctg gccgtgatcg accaggtcga gcaggccgcg cagcaggccg gcgatgtcac
    44281 ggcggtgcgc tcggtacgac tccaggtggg tgaactggcc ggtgtcgtac ccgattccct
    44341 ctccttctgc ttcgaactgg cctgcgccgg aaccgtgctg gagggcgccg acctggtcac
    44401 cgaagaggtg ccggggcggg cccgctgcgc accctgcgcg cgcgaatggt ccgtcggcat
    44461 gccgccccgg ctgagctgcc ccgagtgcgg cggggcgaga gtcgacctgc tctccggccg
    44521 tgaactacag atcgtcagcg tgcactggga ggacggccgg acgcacgcgc aaacccgcga
    44581 accgatctcc gaggagcgct gaaccatgtg ccgtgtggtc gacctgcacc aggccgtgct
    44641 cgccaagaac gacgcgagcg cgcacactct gcgcgccgaa ctggcggctc gcggcaccgc
    44701 ggtggtcaac ctgttgtcca gccccggcag cggaaagacc gcgctgctgg aacgcgaact
    44761 gctgctggca cgggagcggt cggtgcccgt cgccgcgctg accgccgacc tcgccaccga
    44821 gaacgacgcg agacggctgg cgcgttcggg cgtaccggtc aagcaggtgc tcaccgacgg
    44881 gctgtgccat ctggaggccg ggatgctcag ccggcacctc gacggatggc tgcccgacaa
    44941 cacccggctg ctgttcgtgg agaacgtcgg caacctggtc tgcccggcct cctacgacct
    45001 gggcgagact ctgagagtcg tcctcgcctc cgtcaccgag ggcgaggaca agccgctgaa
    45061 gtaccccacc gcgttcggtc tcgcccacct ggtcgtcgtc accaagaccg acatcgccga
    45121 ggccgtcgac ttcgacgagg ccgcgttccg cgcgcacgtc gagcaggtca acccaggagt
    45181 cgaggtgctc ctgacctcgg cacgccgggg ccgggcgatc ggcgcgctgc tcgacagggc
    45241 gctggcggcc gcggacggcg cgccgctcca caggcctgtc atggcccgac ggacggatgt
    45301 cctcggaccc gccggccccg cgcacgacca cggccacggc gacggccatg agcatgccca
    45361 caccggcccc gcgcacgatc acggccatgc ccacccggac ggtaccggcg ccatggccca
    45421 gacccgctcg tgagtggtcc gcggccctcg gccgtcgtcc ccggtgacat gccgcggcgc
    45481 cgtcgggtca ccgttcgggg cgtggtgcag ggtgtgggct tccggccgta cctgtacggc
    45541 ctcgccaccg agctcgccct ggccggacat gtgaccaaca cgccggaggg cgtcgtcgtc
    45601 gaagtcgagg gaacaccctc ggccgtcgac cggttctgcg accggatcgc cgcacaggcg
    45661 cccccgctgg cccgcgtgga gtccgtccac caccaggacc tgcccgccac gggcggcggc
    45721 gcgttcacca tcctcgcctc ccgtgccgac gggccggtac gcaccctggt ctccccggac
    45781 atggccacct gcgccgactg cctcgacgaa ctggccgact ccgccgaccg gcgctaccgc
    45841 catcccttcg tcaactgcac ccactgcggc ccgcgcttca cgatcgtcac cggtgttccc
    45901 tacgaccgcg cccacaccac catggccggc ttcgcgatgt gccccgactg cgcccgggag
    45961 tacgccgatc cggccgaccg ccgcttccac gcccagccgg tcgcctgccc cgcctgcggt
    46021 ccgagcctgc gtctgctcgt tggccggcag ccgctcgacg gacggccgca gagcgtcgcc
    46081 ggggcggacc cggtcaccga ggcccgcacg cttctggcgc gcggcgcgat cctcgcggtg
    46141 aagggactgg gcggctacca cctggcctgc gacgcctcgg accccgcagc cgtcgccctg
    46201 ctgcgccgcc gtaaggcccg cggggacaaa ccgttcgccg tcatggccag gagcgcggac
    46261 gacatcgagc acctcgtccg gctcggtccc gaggagcgaa gcctgctgga gggcggcacc
    46321 aggcccgtcg tgctgctgcg tcggcgtacg gacccctcgt acccggcagg agcaccgcgg
    46381 ccggccgagg ccgtcgcgcc cggcagcccc gacctcggcg tgatgctccc gtacacgccc
    46441 ctgcaccatc tgctgctcgg tctgcccggc gacgccgaag ggccccggct gctcgtcatg
    46501 accagcggca atgtggccgg tgagccgatc gtcaccgacg acgcggaggc actggagcgg
    46561 ctggcgccgc tggccgatgc ctggctcacc cacgaccggc cgatccaggt gccgtgcgac
    46621 gactccgtgg tccgcgtcag tgacggaaag ccgctgatga tccgccgagc ccgcggctac
    46681 gccccgctgc cggtgcccct cccgctgtcc gtccggccgg ccctcgccgt cggcggggac
    46741 ctcaagaacg cgttttgtct cggggaggac cggcgggcct ggctgtccgc gcacatcggc
    46801 gacatggacg acctcggcac ccagcgagcc ttcgggcgcg ccacggcgca actggagtcc
    46861 gtcaccggcg tgcggcccag catgctggtg gccgaccggc accccggcta ccgctccgcc
    46921 cgatgggccg accggaacgc ggccgggcgg cccgtcgtac gcgtccagca ccatcacgcc
    46981 cacgtggccg ccgcgatggc cgaacacggg ctggagggca cccggccggt gatcggagtg
    47041 gccttcgacg gcacgggcca cggcgacgac ggcgccgtgt ggggcgggga gatcctgctc
    47101 gcggactacg acggtttcac ccggttcggg cacctcaggt acgtcccgct gcccggtggt
    47161 gacgccgccg tgcgccggcc gtaccgcatg gcgctggccc atctgcgcgc cgccgggatc
    47221 ggctggtcgg acgacctcgc ctgtgtggcc gcctgcccgc ccgacgaacg ccgcgtgctg
    47281 gaacgccaac tggagcgaga cctgaactgt gtccccacct ccagcatggg ccggctcttc
    47341 gacgccgtgt cctcgctcgc gggcgtgtgt caccgggccg ggtacgaggc ccaggccgcc
    47401 gtcgagctgg aggccgccgc gctgaacgcg cccgtcgagg acgtcaccgc ctacgcgttc
    47461 gccctccggg cgtcggagcc ggacgggggc ggcgcggtac gggccgaccc ggcacccgtc
    47521 ctcgcggcga tcgtcggtga cctgcgagcg ggcaccgaac cggctctggt cgcggcccgc
    47581 ttccaccggg ccgtcaccgg tctcgtgcac cggatctgtg tgcgggcccg cgagcgtcac
    47641 gggctggaca cggtggccct gaccggaggc gtgttcgcca acaccctgct ctcctcggcc
    47701 tgcgccacgg ccctgcgcga ggacggcttc acggtgctgc ggcaccacct ggtcccgccg
    47761 ggcgacggcg gtctggcgct cggccagctc atggtggccg cccgtgacac ggcccggacc
    47821 gcgaccaccg gctgaggact gtcccggcag caccgggcga cgcgcgaccc acagcaagac
    47881 agcaaggaga ggcccatgtg cctggcggta cccggcagag tgctggacat cgaggaacgt
    47941 gacggcaccc gaatggccac cgtcgacttc ggcggtgtgg tcaaggaggt gtgcctggag
    48001 tacctgcccg acctccaggt cggcgagtac gccatcgtcc acgtcgggtt cgcactgcaa
    48061 cgcctggacg aggaatcggc gaagcagacg ctcgaactct tcgcccagct cggcatgttg
    48121 caggaggagt tcggcgaccc ctgggaacag gcggcggaag cgggcggggc caccccgccc
    48181 gtgggcgacg ccgtcatcga ggaggtgcgg aagtgaagta catcgacgaa ttccaggacc
    48241 cggaactggc gcgccggctc ctcgacgaca tccactccac ggtgaccagg ccgtgggccc
    48301 tgatggaggt ctgcggaggt cagacgcaca ccatcatccg gcacggcatc gaccaactcc
    48361 tcccggaaca ggtcgagttg atccacggcc cgggctgtcc cgtgtgcgtg accccgctgg
    48421 aggtcatcga caaggctctg gagatcgcct cccggccgga ggtgatcttc tgctccttcg
    48481 gtgacatgct ccgtgtgccc ggcaccggtc gcgacctgtt ccaggtacgc agcgaaggcg
    48541 gcgatgtacg cgtcgtctac tcgccgctcg acgccctgcg gatcgcgcgg cagaacccgg
    48601 accgcgaggt ggtgttcttc ggcatcggct tcgagacgac ggcacccccc aacgccatga
    48661 cggtccatca ggcccgtcgg ctcggcatcc cgaacttcag cctgctggtg tcccacgtcc
    48721 gggtgccgcc cgccatcgag gcgatcatgt cggcgccgaa ctgccgcgtc caggccttcc
    48781 tcgcggccgg gcacgtgtgc agcgtgatgg gcgtggggga gtacccggaa ctggccgaac
    48841 gcttccgcgt cccgatcgtc gtgaccgggt tcgagccact ggacatcctc gaaggcgtac
    48901 gccgcaccgt tctccagctg gaacggggtg agcacaccgt cgacaacgcg tacgcccgtg
    48961 ccgtccgccc ggagggcaac ccggccgcgc aggccatgct cgaggatgtc ttcgaggtca
    49021 ccgaccgggc ctggcgaggc atcggtgtga tccccgacag cggctggcgg ctgtcaccca
    49081 agtaccgcga ccacgacgcc gagtaccgct tctcggtcga cgggatccag acgcgcgaac
    49141 cggccgaatg ccgcagcggc gaggttctgc agggaatgct gaagccgcac gagtgcgagg
    49201 ccttcggcac cgtctgcaca ccccgtaccc ccctgggagc caccatggtc tccagcgagg
    49261 gcgcctgcgc cgcgtactac ctctaccggc gactggacat caccaccgcc gcccgggagg
    49321 cgagccccgt tgtctgagac caccgatctc cgcgggccgg cgaccctcga ggcctggacc
    49381 tgtcccgccc cgctgcgtga ccggccgcgc gtcgtcatgg gccacggcgg aggcggggca
    49441 ctctccgccg agctggtcca gcacgtcttc gcccccgcct tcgggggaga ggtgctcgcc
    49501 cagatgggtg acgccgccgc tctctcgctg ggcggtgtcc ggctggcgtt ctccaccgac
    49561 tccttcgtgg tgcggccgct gttcttcccc ggcggcagca tcggcgatct cgccgtcaac
    49621 ggcaccgtca acgacctcgc catgagcggc gcccgcgccg cctacctctc ctgcggattc
    49681 atcctggagg agggcgtcga agtggaggtg gtcgcccggg tggccgaggc gctgggggcg
    49741 gcggcgcgca ccgccggcgt cgaggtggcg accggcgaca ccaaggtggt ggaggcagga
    49801 cacggcgacg ggatcttcat caacacggcg ggcatcggcc tcatcccggc gggcgtcgat
    49861 ctgcgtccgc agcgggtcgt ccccggcgac gtcgtcatcg tcagcggtgc catcggcgta
    49921 cacggtgtgg cgatcatgag cgtccgcgaa ggcctggaat tcggtgtgga gatcgaaagc
    49981 gactgcgcgg cgctcggcgg cctggtcgac gccatgctcg ccgtcacccc ggatctgcat
    50041 gtgctgcgcg atcccacgcg aggggggctg gcggccgcgc tgaacgagat cgcggcggcc
    50101 tccggcgcgg gggtggtcgt ccgggagcgc gacgtcccgg ttccgccggc cgtggccaac
    50161 gcctgcgcca ttctgggcct ggaccccctg tacgtcgcca atgagggcaa gctggtggcc
    50221 ttcgtgccgc gcgagcacgc cgacgcggtc ctgggcgcga tgcgggccca cccgctgggt
    50281 gccgacgcca ggatcatcgg cgaggcggtg gaggcccacc cagggatggt ggtggcccgg
    50341 acgggactgg gcggcaccag ggtcgtcgac ctgccgatcg gcgagcagtt gccgcggatc
    50401 tgctgagacg cggctccgcc cggcgaggag aggaccggga cggccggggt ggcgccgagc
    50461 gggcggcgct aacccggccg atgcctggac ggcgggtcct tggggtccac accggtgtag
    50521 gaggaagcgt ccttgctgcc gctgggccgc tgggagcgac ccctgcggcc ggtgtcctgc
    50581 ctgccctctt cggactcctc ggcgtactcc tcgccgcgcg cgctgccgct cttcgcggtc
    50641 tcaccgggaa cggacttcgt ctcctccgcg gacttcgtcc ggccccggcc cctgtcgccg
    50701 gcgtgttcgg ctgggtggaa ggagcggtga gcgctcgggt tgtcctgctg acgggtctca
    50761 tccacatcag gtgaccagcc gtgctgcccg gtaccccggt gacgactcgg gccctccccg
    50821 tgcgacggct cggacgaatg tgatttcttc ggcatgggcc gacctgcctg ttcagtgtgg
    50881 gagcgccggc tgcgcgtctc cgcgatgggg aaattctccc actatgtgat gcattggtca
    50941 cattgttgtc cggtgcggac gggttccgga caggccggga tcggttccgg attccggttc
    51001 cgtttcgggt tcgacggtgc ctcgtccggc gcgggcggcg cggtcacccg cgcgcgggca
    51061 tgtgtcgccg gccggccctg gggtactcgc ggcgccggcg gaagacaggg atgaccggta
    51121 ggccggtacc ccgacggcgc aggaaagctt ggtacccccg tgctctcccg gggcgggggc
    51181 accagcctgc ggcgcggcgg tggacaccgg tgtacggtgt ccaccgccgc gccggatgcc
    51241 agggcctcag ccccggcgtc gctacggggt tcacgacctc ccggggccgc cgctgccgaa
    51301 cgaaccgccg gcgccctcgt cccagcgtgg ccgctgctgg ttctcgctcg gtttgcttcc
    51361 ggacgcgtgg aggtcgtgcg gggtgagccg ttcgctctcg ttcgccgccc tggggacctc
    51421 gtcgggctcc cgcctctgtc gcgtctcgtg aaccggcccg gactccggca gcgtgggctg
    51481 ctcctcgcgt cggggcggtc ccggctcgcg gcggcgcacc ttggtgccga agcgcaccgc
    51541 ccacaccaac gcgccgacga tgaccagacc gccgacgaag gcggcgaaca ttccgaaagc
    51601 ggcattcgaa gcaattgcct catagtgggt cgtgttcatt tctgtcgagt accccggacc
    51661 tcggcggcga ta
//
