LOCUS       NC_003155              33876 bp    DNA     linear   CON 12-JUL-2024
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893, complete sequence.
ACCESSION   NC_003155
VERSION     NC_003155.5
KEYWORDS    RefSeq.
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Ikeda,H., Kazuo,S.Y. and Omura,S.
  TITLE     Genome mining of the Streptomyces avermitilis genome and development
            of genome-minimized hosts for heterologous expression of
            biosynthetic gene clusters
  JOURNAL   J Ind Microbiol Biotechnol 41 (2), 233-250 (2014)
   PUBMED   23990133
REFERENCE   2
  AUTHORS   Ikeda,H., Ishikawa,J., Hanamoto,A., Shinose,M., Kikuchi,H.,
            Shiba,T., Sakaki,Y., Hattori,M. and Omura,S.
  TITLE     Complete genome sequence and comparative analysis of the industrial
            microorganism Streptomyces avermitilis
  JOURNAL   Nat Biotechnol 21 (5), 526-531 (2003)
   PUBMED   12692562
REFERENCE   3
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kikuchi,H., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Genome sequence of an industrial microorganism Streptomyces
            avermitilis: deducing the ability of producing secondary metabolites
  JOURNAL   Proc Natl Acad Sci U S A 98 (21), 12215-12220 (2001)
   PUBMED   11572948
REFERENCE   4  (bases 1 to 9025608)
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kushida,N., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2002) Contact:S Omura Kitasato University,
            Kitasato Institute for Life Sciences; 1-15-1 Kitasato, Sagamihara,
            Kanagawa 228-8555, Japan URL
            :http://avermitilis.ls.kitasato-u.ac.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000009765.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:55:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,040
            CDSs (total)                      :: 7,942
            Genes (coding)                    :: 7,651
            CDSs (with protein)               :: 7,651
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 293
            CDSs (without protein)            :: 291
            Pseudo Genes (ambiguous residues) :: 0 of 293
            Pseudo Genes (frameshifted)       :: 128 of 293
            Pseudo Genes (incomplete)         :: 220 of 293
            Pseudo Genes (internal stop)      :: 25 of 293
            Pseudo Genes (multiple problems)  :: 77 of 293
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:08:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7918325
            Orig. end                         :: 7952201
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BA000030.4.
            On Mar 29, 2016 this sequence version replaced NC_003155.4.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..33876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="34"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..33876
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33876
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:18876](-)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15001..18876)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     misc_feature    6..21
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.73"
                     /tool="antismash"
     gene            complement(119..709)
                     /db_xref="GeneID:41543689"
                     /locus_tag="SAVERM_RS34010"
                     /old_locus_tag="SAV_6619"
                     /old_locus_tag="SAVERM_6619"
     CDS             complement(119..709)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642524.1"
                     /locus_tag="SAVERM_RS34010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6619"
                     /old_locus_tag="SAVERM_6619"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_078234564.1"
                     /transl_table=11
                     /translation="MSEPVSEAVTEAAVSGATSGPTGGPVDPADELLDIVDENDRVVGQ
                     SARGEAYARGLRHRCVFILARDGEGRIFVHRRTPTKLVFPSLYDMFVGGVVGAGETYDD
                     AALREAEEELGVCGLPRPAPLFKFLYDNGAGQTWWSSVYEVRCDLPVSPQVEEVAWHDF
                     LPQDEVERRLADWEWVPDGLAAYERLKAHRATG"
     gene            complement(758..1651)
                     /db_xref="GeneID:41543690"
                     /locus_tag="SAVERM_RS34015"
                     /old_locus_tag="SAV_6620"
                     /old_locus_tag="SAVERM_6620"
     CDS             complement(758..1651)
                     /codon_start=1
                     /db_xref="GeneID:41543690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019059168.1"
                     /locus_tag="SAVERM_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6620"
                     /old_locus_tag="SAVERM_6620"
                     /product="DMT family transporter"
                     /protein_id="WP_037646648.1"
                     /transl_table=11
                     /translation="MSVLVLVLAVSAAFCLGIGFVLQQNAAQHAPLSDFLSPRLLLDLM
                     HVRRWLGGIGFMVVGMVLGAVALAHGELSLVEPLLATNLLFALGLSRRQTKQPLGRQGW
                     AGLALLAGGVTAFIVAGQPTGGDAVTNPLRHWVIIGVMVGFALLLTTYAKQSRLSAAPV
                     LLSLAAGLLYGVQDALTRVSGQRFSEGGWPELVTGWQPYAVLALGVTGLVLVQSAFETA
                     PLRMSLPALTAAQPLAGIVCGVGFLGDQLRTDTGALAWEAAGLAAVVLGIVLLGLHPAM
                     PRGSAEAERQRDLQPH"
     gene            1863..3518
                     /db_xref="GeneID:41543691"
                     /locus_tag="SAVERM_RS34020"
                     /old_locus_tag="SAV_6621"
                     /old_locus_tag="SAVERM_6621"
     CDS             1863..3518
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524022.1"
                     /locus_tag="SAVERM_RS34020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6621"
                     /old_locus_tag="SAVERM_6621"
                     /product="FAD-binding dehydrogenase"
                     /protein_id="WP_010988022.1"
                     /transl_table=11
                     /translation="MAHDADVIVIGAGLAGLAATAELVDAGRKVILLDQEPEQSMGGQA
                     FWSFGGLFFVDSPEQRRLRIKDSHALALQDWMGTAGFDRPEDHWPRKWAEAYVDFAAGE
                     KRAWLHRQGVRFFPVVGWAERGGYDANGHGNSVPRFHITWGTGPGLIEPFVRRVRAGVA
                     RGLVELRFRHRVTGLSRSAGAVDTVTGEVLEASDIQRGRASSREVTGAFELTAQAVIVT
                     SGGIGGNHDLVRANWPERLGRAPEKMISGVPAHVDGRMLAIAEGAGARLINRDRMWHYT
                     EGIQNWNPIWHNHGIRVLPGPSSLWFDARGNRLPVPLFPGFDTLGTLEHIMKTGYDYTW
                     FVLDQKIIGKEFALSGSEQNPDLTGKSIKDVIGRARAEVPGPVKAFMDHGVDFVVEKDL
                     GALVRGMNALTKEPLIDEAALRREIVARDREIANPFTKDLQVTAMRGARRFLGDKLIRT
                     AAPHRILDPKAGPLIAVRLNILTRKTLGGLETDLSSRVLTEGGAPLEGVYAAGEAAGFG
                     GGGVHGYRSLEGTFLGGWLFSGRTVGRAAAQAVG"
     misc_feature    complement(3547..3565)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 20.96"
                     /tool="antismash"
     misc_feature    complement(3882..3897)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.15"
                     /tool="antismash"
     gene            3988..4938
                     /db_xref="GeneID:41543692"
                     /locus_tag="SAVERM_RS34025"
                     /old_locus_tag="SAV_6622"
                     /old_locus_tag="SAVERM_6622"
     CDS             3988..4938
                     /codon_start=1
                     /db_xref="GeneID:41543692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004990188.1"
                     /locus_tag="SAVERM_RS34025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6622"
                     /old_locus_tag="SAVERM_6622"
                     /product="hypothetical protein"
                     /protein_id="WP_010988023.1"
                     /transl_table=11
                     /translation="MPPPPPPLGRGRKRAAHAFDAALDDAELVASRASLTQGRWAPVRA
                     LLAATRDDWDRRGHRVTVLAQESAALPWAREWQLAEPESPCAAVLLACATVHRALNGKE
                     RPQTAREACHAAAALAPDDPTPWLGLLILERSLGTDEDVVRLFDEVRHRCPDHHHAHQL
                     IVARLAERRADAGRDPLHEVYDFANWAAEQAPADSPLAILPVVAHAERYRVLAAAGAEP
                     ADPVASGHWVGRRARQVMKAAFDWWLEWERDDHPRRFVDLNFLAHAKFCEGRGAEAAAL
                     FHRIGEHATPAPWSYPDRDPYQAFSAARASALGAP"
     gene            5053..6615
                     /db_xref="GeneID:41543693"
                     /locus_tag="SAVERM_RS34030"
                     /old_locus_tag="SAV_6623"
                     /old_locus_tag="SAVERM_6623"
     CDS             5053..6615
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543693"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933347.1"
                     /locus_tag="SAVERM_RS34030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6623"
                     /old_locus_tag="SAVERM_6623"
                     /product="APC family permease"
                     /protein_id="WP_010988024.1"
                     /transl_table=11
                     /translation="MTTGSSSTSESRPANRSAVADDISTFKGQERALRADRLGTAGLLL
                     SVLAATAPLMVVAGVMPTTFGVMGIVGQPLLFVVLGAVLALFSLGYAEMSRHVHNAGAF
                     YAYISRGLGGTAGAGAAAVALVAYSALQFAIYGIFGFEVSGLCATYLELQVAWWIPALA
                     AVLAVGALGLLKIDVNARVLGVLLLIEVVLVVVFDIAAVADPAKEGLSLHAFNPDTLTG
                     AGVGTALCFCVAAFLGFEQAPVYAEETSRPDVLVPRVMFLAIGFVAVFFAVSCWAFTVA
                     AGPSTIVAAAQKQSAGLLFQLTESRLGGTFTDVLHVLFVTGMFAAMLSFHNVVARYAFA
                     MGREGLLPAAFGRTTGASGAPGTGSLLQTAVSAVIVIAFAMADDKPAGDPTAPVLHLFT
                     WFGSVGALGVTLLMVAASLSVIVFFARRGAARAQAWRLATSAVSGAALLVIVGYTVKDF
                     GVLVGTGPDSALGWVLPAIIGVALVLGLAQGLVLRSRKPQAHARIGLDNEAFQLDKAAE
                     SAT"
     gene            6752..7525
                     /db_xref="GeneID:41543694"
                     /locus_tag="SAVERM_RS34035"
                     /old_locus_tag="SAV_6624"
                     /old_locus_tag="SAVERM_6624"
     CDS             6752..7525
                     /codon_start=1
                     /db_xref="GeneID:41543694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006135981.1"
                     /locus_tag="SAVERM_RS34035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6624"
                     /old_locus_tag="SAVERM_6624"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_037646419.1"
                     /transl_table=11
                     /translation="MNPEHPEEREAPEPEKREAPEPEGRGTPIGRRVLLGTLGLGALGV
                     VAAPVLQRGMESVLAGAAEKDPTGLTGLLPNGGGFRYYSVTSSVPHKGEANYRLTIDGL
                     VDHPTSFTLADLRALPQTRLVRDVQCVTGWRVPGTPFEGVRLSRLLDAAGVRSSARAVR
                     FTCFDGAYTESLTLAQARRADVLVALRMQDKPLGHNHGGPVRLYVAPMYFYKSAKWLSG
                     ITVTEDVRPGYWEDRGYDVDAWVGKSNGRDDDPTS"
     misc_feature    6764..6781
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            7509..8165
                     /db_xref="GeneID:41543695"
                     /locus_tag="SAVERM_RS34040"
                     /old_locus_tag="SAV_6625"
                     /old_locus_tag="SAVERM_6625"
     CDS             7509..8165
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671735.1"
                     /locus_tag="SAVERM_RS34040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6625"
                     /old_locus_tag="SAVERM_6625"
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="WP_010988026.1"
                     /transl_table=11
                     /translation="MTLRADAPAPAVSSRVRRFTRAERWVHRVTAALMGVCVVTAACLY
                     IPVFAELVGRRDLVVRVHEWAGLLLPAPVLAGLASRAFRSDLGHLNRWGPHDRVWLRAV
                     LRRDARPSSRPAAKFNAGQKTYAAWIAGASLVMVGTGLLMWFTHLTPLMWRTSATFVHD
                     WLALTIGVVLAGHIGMALADPEARRGLRTGSVSREWASQEHPLWREGPPGGDRRG"
     gene            complement(8438..9463)
                     /db_xref="GeneID:41543696"
                     /locus_tag="SAVERM_RS34045"
                     /old_locus_tag="SAV_6626"
                     /old_locus_tag="SAVERM_6626"
     CDS             complement(8438..9463)
                     /codon_start=1
                     /db_xref="GeneID:41543696"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066054.1"
                     /locus_tag="SAVERM_RS34045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6626"
                     /old_locus_tag="SAVERM_6626"
                     /product="L-idonate 5-dehydrogenase"
                     /protein_id="WP_010988027.1"
                     /sec_met_domain="ADH_N (E-value: 2.7e-28, bitscore: 96.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.1e-20, bitscore:
                     71.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGCVIHGRGDLRVDELPEPAAGPGQALVAVRYGGVCGSDLHYWR
                     HGGVGDFRLREPMVLGHEVVGTVLSYGPGAAGPAPGTAVAVHPATPCGVCPECADGRAN
                     VCRDTRYLGSAARMPHVQGGFAARVVVPAAQVRALPEGLDLRRAALAEPLSVALHAVRR
                     AGPVAGRPVLVTGAGPIGCLVVAAAKAAGAGRVTVTDLLPRALSYAAGVGADDVVRADD
                     PADAGWPDSVDVAVEASGVAAGLDTCLRLVRRGGVVVQLGMLPPGQTPFAGNLVVSREI
                     ELRGAFRFADEFDEALTLLAREPAFDSLISAVVPLEEAESAFALAADRGEACKVLLDFG
                     V"
     gene            complement(9476..10234)
                     /db_xref="GeneID:41543697"
                     /locus_tag="SAVERM_RS34050"
                     /old_locus_tag="SAV_6627"
                     /old_locus_tag="SAVERM_6627"
     CDS             complement(9476..10234)
                     /NRPS_PKS="Domain: PKS_KR (11-119). E-value: 2.3e-12.
                     Score: 39.1. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS34050_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:41543697"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128268.1"
                     /locus_tag="SAVERM_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6627"
                     /old_locus_tag="SAVERM_6627"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_010988028.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-36, bitscore:
                     124.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHPLFDIAGRTALVTGSSRGIGRALARGLLEAGCTVVLNGRDGD
                     RLTAAAAELPGDVRTAAFDVTDGPSVAAGIAEVEERVGPLDILVNNAGIQLRAPLLEFT
                     DSDWHRILNTNLTSAFLVGREAARRMTERGHGKIVNICSLQSEVVRPGIAPYAATKGAL
                     KMLTKGMCADWGPYGVQVNGLGPGYIETELTRPLVEDEEFSAWVRHRTPAGRWGRTEDL
                     VGGVLFLASPAADFVSGQVLYVDGGMTSVL"
     CDS_motif       complement(9818..9868)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34050_0002"
                     /evalue="2.80E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="SAVERM_RS34050"
                     /protein_end="139"
                     /protein_start="122"
                     /score="7.1"
                     /tool="antismash"
                     /translation="GREAARRMTERGHGKIV"
     aSDomain        complement(9878..10201)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS34050_PKS_KR.1"
                     /evalue="2.30E-12"
                     /label="SAVERM_RS34050_PKS_KR.1"
                     /locus_tag="SAVERM_RS34050"
                     /protein_end="119"
                     /protein_start="11"
                     /score="39.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGRALARGLLEAGCTVVLNGRDGDRLTAAAAELPG
                     DVRTAAFDVTDGPSVAAGIAEVEERVGPLDILVNNAGIQLRAPLLEFTDSDWHRILNTN
                     LTSA"
     CDS_motif       complement(10109..10195)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34050_0001"
                     /evalue="4.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SAVERM_RS34050"
                     /protein_end="42"
                     /protein_start="13"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LVTGSSRGIGRALARGLLEAGCTVVLNGR"
     gene            complement(10245..11642)
                     /db_xref="GeneID:41543698"
                     /locus_tag="SAVERM_RS34055"
                     /old_locus_tag="SAV_6628"
                     /old_locus_tag="SAVERM_6628"
     CDS             complement(10245..11642)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015295 - solute:proton symporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015718 - monocarboxylic acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128269.1"
                     /locus_tag="SAVERM_RS34055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6628"
                     /old_locus_tag="SAVERM_6628"
                     /product="gluconate:H+ symporter"
                     /protein_id="WP_010988029.1"
                     /transl_table=11
                     /translation="MTRLSVEKLAADTVEPITSAGHAQLGIAVLAGIAVIVLLITKFKL
                     HAFLALTIGSLALGAFAGAPLDKTIVSFTAGLGSTVAGVGVLIALGAILGKLLADSGGA
                     DQIVDTILAKAGGRAMPWAMVLIASVIGLPLFFEVGIVLLIPVVLMVAKRGNYSLMRIG
                     IPALAGLSVMHGLIPPHPGPLVAIDAVKANLGLTLALGVLVAIPTVIIAGPVFSKYAAR
                     WVDVPAPDRMIPTRASEDLDKRPGFGATLATMLLPVVLMLAKALVDIIVDDPTHQVQRV
                     FDVIGAPLIALLAAVIVGMFTLGRAAGFTKERLSTTVEKSLAPIAGILLIVGAGGGFKQ
                     TLIDSGVGQMILEISKDWSIPALLLAWLIAVAIRLATGSATVATISAAGLVAPLAADMS
                     TAHTSLLVLAIGAGSLFFSHVNDAGFWLVKEYFGLSVGQTVKTWSIMETIISVVAGGLV
                     LLLSLVI"
     misc_feature    11638..11653
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(11744..12280)
                     /db_xref="GeneID:41543699"
                     /locus_tag="SAVERM_RS34060"
                     /old_locus_tag="SAV_6629"
                     /old_locus_tag="SAVERM_6629"
     CDS             complement(11744..12280)
                     /EC_number="2.7.1.12"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325262.1"
                     /locus_tag="SAVERM_RS34060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6629"
                     /old_locus_tag="SAVERM_6629"
                     /product="gluconokinase"
                     /protein_id="WP_010988030.1"
                     /transl_table=11
                     /translation="MEQVHTPHVVVVMGVAGTGKTTIGPLLAARLGVPYAEGDDFHPPA
                     NIAKMSAGVPLDDVDRLPWLDAIGAWAHSRAGLGGVVSSSALKRSYRDRLRAAAPGVVF
                     VHLTGDRELIEDRMSHRQGHFMPTALLDSQFATLQPLAADEAGVAVDVTGGPEEISERA
                     VTALRALEPASQPAK"
     misc_feature    12279..12293
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            12412..13113
                     /db_xref="GeneID:41543700"
                     /locus_tag="SAVERM_RS34065"
                     /old_locus_tag="SAV_6630"
                     /old_locus_tag="SAVERM_6630"
     CDS             12412..13113
                     /codon_start=1
                     /db_xref="GeneID:41543700"
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977147.1"
                     /locus_tag="SAVERM_RS34065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6630"
                     /old_locus_tag="SAVERM_6630"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_010988031.1"
                     /transl_table=11
                     /translation="MTTPGRGLHGHVLETLGPAIAAGTYPPGSVLRTDELAQRFEVSRS
                     VMREAVRVLESMHLVESRRRVGVTVRPKAEWNVYDPQVIRWRLAGADRPHQLRSLTVLR
                     SAVEPAAAGLAARHATADQCADLTECALGMVATSRGHQLEAYLVHDVAFHRVILNASGN
                     EMFARLGDVVAEVLAGRTHHEVMFEDPDPAAVTLHVQVAEAVREGDALRAEQLTREITV
                     GALQELDILAP"
     gene            complement(13125..13547)
                     /db_xref="GeneID:41543701"
                     /locus_tag="SAVERM_RS34070"
                     /old_locus_tag="SAV_6631"
                     /old_locus_tag="SAVERM_6631"
     CDS             complement(13125..13547)
                     /codon_start=1
                     /db_xref="GeneID:41543701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988032.1"
                     /locus_tag="SAVERM_RS34070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6631"
                     /old_locus_tag="SAVERM_6631"
                     /product="YchJ family metal-binding protein"
                     /protein_id="WP_010988032.1"
                     /transl_table=11
                     /translation="MSKSRRTRSTSRPTSRPQPASCPCGLPEVYEACCGRFHSGAADAP
                     TAALLMRSRYCAFVRRDEAYLLRTWHPRTRPAEVDFDPRMRWTGLEILGTTEGSAFHSA
                     GTVTFRASYRGGALQERSRFERIGGAWVYVDGEFFE"
     gene            complement(13544..14923)
                     /db_xref="GeneID:41543702"
                     /locus_tag="SAVERM_RS34075"
                     /old_locus_tag="SAV_6632"
                     /old_locus_tag="SAVERM_6632"
     CDS             complement(13544..14923)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007380905.1"
                     /locus_tag="SAVERM_RS34075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6632"
                     /old_locus_tag="SAVERM_6632"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_037646421.1"
                     /transl_table=11
                     /translation="MSPRQKAEADPYFPTNGDARYRVHRYELTLDYRPGPNRLAGTARL
                     NAIAGRAPLAEFQLNLADFRIGRVRVDGKAPHYTHRGGRLRIRPPKPVRAGAAFTVEVH
                     WSGNPQPVNSAWGGLGWEELEDGALVASQPVGAPSWYPCNDRPADKAAYQLSVTTPSAY
                     SVVAGGRLLTRTTKASTTTWVYEQPAPTSSYLVGLSIGKYQTVLLGDPGLGGVPQTGHI
                     PAHLLTEFSRDFARQPAMTELFEELFGPYPFGEYAVVVTEEELDVPVEAQGLSLFGANH
                     VDGKRGSERLVAHELAHQWFGNSVTIADWRHIWLNEGFAKYAEWLWSERSGGRTAQQLA
                     TLAHRKLSSLPQDLRLADPGRKLMFDDRLYERGGLVLHAVRCALGDEAFFRMLRGWAGV
                     HRGGVVTTAAFTTHAARFSAQPLDELFTAWLEETALPSLPVLAAPVPARPPYPPHITGS
                     A"
     gene            complement(15001..18876)
                     /db_xref="GeneID:41543703"
                     /locus_tag="SAVERM_RS34080"
                     /old_locus_tag="SAV_6633"
                     /old_locus_tag="SAVERM_6633"
     CDS             complement(15001..18876)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (42-414). E-value: 3.3e-75.
                     Score: 245.1. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS34080_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (517-585). E-value: 2.5e-15. Score:
                     48.4. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS34080_PCP.1"
                     /NRPS_PKS="Domain: TIGR02353 (603-1284). E-value: 7.7e-277.
                     Score: 912.0. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS34080_TIGR02353.1"
                     /codon_start=1
                     /db_xref="GeneID:41543703"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009331530.1"
                     /locus_tag="SAVERM_RS34080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6633"
                     /old_locus_tag="SAVERM_6633"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_010988034.1"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-61, bitscore:
                     206.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.5e-06, bitscore:
                     25.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1e-274, bitscore:
                     912.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALQQGPALALSDDEVRAEFGDRARFSAGSPASPRTLVDILDAS
                     VRAYPDEPALDDGRRCLTYRALAVEIEALRRRLAAAGVGLGDRVGVRVPSGTNDLYIAV
                     LAVLAAGAAYVPVDAEDPDERAELVFGEAEVRAVVGAGHHLTVDGTAGVPAARPGTGHD
                     AWIIFTSGSTGRPKGVAVSHRSAAAFVDAEADLFLTEEPIGPGDRVMAGLSVAFDASCE
                     EMWLAWRYGACLVPVPRSQVRGGADLGPWLVEQEITVVSTVPTLAALWEPEALSDVRLL
                     IFGGEACPPELAERLVTEGREVWNTYGPTEATVVACASLLTGNEPIRIGLPLGGWELAV
                     VDEAGEPVPMGGSGQLVIGGVGLARYLDAEKDAEKYAPLASLGWARAYRSGDLVRAEPE
                     GLVFLGRADEQIKLGGRRIELGEVDAALQALPGVAGAAAAVRTARSGNQLLVGYVVTQD
                     GWDQAAAVEKLRAELPAALVPLLAPVADLPTRTSGKVDRTALPWPLEGVEAPTAELYGT
                     EAWLAEQWTEVLGIPVGGAGDDFFAIGGGSLAAAQLTTRLRTRYPGAAVLDVYQQPVLR
                     KLARRLERSTRDDGAARVIAPVPPRAKALQLLLLIPLFTLLGLRWTVALAALGNVLHRF
                     GPYPWAPSASWWVVTAGAVLFFSPPGRLAIAAGGARLLLRGLRPGRYPRGGSVHLRLWT
                     AERLAEFSGATSLTGSWLERYARALGAKVGADVDLHSLPPVTGMLKLGRGAAVESEVDL
                     SGHWLDGDRLEIGPVRVGAHAVVGTRSILFPGARVGKRAEVAPGSAVAGQIPTGQRWAG
                     APAGKLGKAKRAWPEERPRRGTYWRAMYGAAGFALSALPVLAGLAALLVAGVFVAPDAG
                     LGAALRGAAIALVPATLAFGCAYALLLLLAVRLLSLGLREGTHPTHSRTGWQAWTVTQL
                     MDRSRETLFPLYAGLITPVWLRLLGMRIGRGAEVSTVLALPSLTTVGEGAFLADDTLTA
                     PYELGGGWMRIGRAQIGRRAFLGNSGMTAPGRSVPDGGLVGVLSATPKKAKKGSSYLGL
                     PPVKLPRSTRDGDQSRTYDPPARLLWGRALVELCRIVPVFCSAALVVLTVAALSALGGW
                     APLLAGLVFLGAGVLACLTSVVAKWLLVGRHRAGEHPLWSGFVWRNELADTFVEVVAVP
                     WLAGSVPGTPLMTAWLRGLGARIGKGAWIESYWLPETDLVTLEDATTVNRGCVLQTHLF
                     HDRILRTDTVVLREGATLGPGGIVLPGSTVGARSTLGPASLVMAAESVPDDTRWLGNPI
                     EAWRPRA"
     aSDomain        complement(15025..17067)
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS34080_TIGR02353.1"
                     /evalue="7.70E-277"
                     /label="SAVERM_RS34080_TIGR02353.1"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="1284"
                     /protein_start="603"
                     /score="912.0"
                     /tool="antismash"
                     /translation="ALQLLLLIPLFTLLGLRWTVALAALGNVLHRFGPYPWAPSASWWV
                     VTAGAVLFFSPPGRLAIAAGGARLLLRGLRPGRYPRGGSVHLRLWTAERLAEFSGATSL
                     TGSWLERYARALGAKVGADVDLHSLPPVTGMLKLGRGAAVESEVDLSGHWLDGDRLEIG
                     PVRVGAHAVVGTRSILFPGARVGKRAEVAPGSAVAGQIPTGQRWAGAPAGKLGKAKRAW
                     PEERPRRGTYWRAMYGAAGFALSALPVLAGLAALLVAGVFVAPDAGLGAALRGAAIALV
                     PATLAFGCAYALLLLLAVRLLSLGLREGTHPTHSRTGWQAWTVTQLMDRSRETLFPLYA
                     GLITPVWLRLLGMRIGRGAEVSTVLALPSLTTVGEGAFLADDTLTAPYELGGGWMRIGR
                     AQIGRRAFLGNSGMTAPGRSVPDGGLVGVLSATPKKAKKGSSYLGLPPVKLPRSTRDGD
                     QSRTYDPPARLLWGRALVELCRIVPVFCSAALVVLTVAALSALGGWAPLLAGLVFLGAG
                     VLACLTSVVAKWLLVGRHRAGEHPLWSGFVWRNELADTFVEVVAVPWLAGSVPGTPLMT
                     AWLRGLGARIGKGAWIESYWLPETDLVTLEDATTVNRGCVLQTHLFHDRILRTDTVVLR
                     EGATLGPGGIVLPGSTVGARSTLGPASLVMAAESVPDDTRWLGNPI"
     aSModule        complement(15025..18750)
                     /complete
                     /domains="nrpspksdomains_SAVERM_RS34080_AMP-binding.1"
                     /domains="nrpspksdomains_SAVERM_RS34080_PCP.1"
                     /domains="nrpspksdomains_SAVERM_RS34080_TIGR02353.1"
                     /locus_tags="SAVERM_RS34080"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(16189..16221)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0006"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="896"
                     /protein_start="885"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="ATLAFGCAYAL"
     aSDomain        complement(17122..17325)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS34080_PCP.1"
                     /evalue="2.50E-15"
                     /label="SAVERM_RS34080_PCP.1"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="585"
                     /protein_start="517"
                     /score="48.4"
                     /tool="antismash"
                     /translation="EAWLAEQWTEVLGIPVGGAGDDFFAIGGGSLAAAQLTTRLRTRYP
                     GAAVLDVYQQPVLRKLARRLERS"
     CDS_motif       complement(17608..17670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0005"
                     /evalue="6.20E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="423"
                     /protein_start="402"
                     /score="28.1"
                     /tool="antismash"
                     /translation="FLGRADEQIKLGGRRIELGEV"
     aSDomain        complement(17635..18750)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS34080_AMP-binding.1"
                     /evalue="3.30E-75"
                     /label="SAVERM_RS34080_AMP-binding.1"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="414"
                     /protein_start="42"
                     /score="245.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DASVRAYPDEPALDDGRRCLTYRALAVEIEALRRRLAAAGVGLGD
                     RVGVRVPSGTNDLYIAVLAVLAAGAAYVPVDAEDPDERAELVFGEAEVRAVVGAGHHLT
                     VDGTAGVPAARPGTGHDAWIIFTSGSTGRPKGVAVSHRSAAAFVDAEADLFLTEEPIGP
                     GDRVMAGLSVAFDASCEEMWLAWRYGACLVPVPRSQVRGGADLGPWLVEQEITVVSTVP
                     TLAALWEPEALSDVRLLIFGGEACPPELAERLVTEGREVWNTYGPTEATVVACASLLTG
                     NEPIRIGLPLGGWELAVVDEAGEPVPMGGSGQLVIGGVGLARYLDAEKDAEKYAPLASL
                     GWARAYRSGDLVRAEPEGLVFLGRADEQIKLG"
     CDS_motif       complement(17782..17832)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0004"
                     /evalue="1.70E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="365"
                     /protein_start="348"
                     /score="10.8"
                     /tool="antismash"
                     /translation="PMGGSGQLVIGGVGLAR"
     CDS_motif       complement(18166..18195)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0003"
                     /evalue="5.30E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="237"
                     /protein_start="227"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="WRYGACLVPV"
     CDS_motif       complement(18328..18387)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0002"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="183"
                     /protein_start="163"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AWIIFTSGSTGRPKGVAVSH"
     CDS_motif       complement(18523..18564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAVERM_RS34080_0001"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="SAVERM_RS34080"
                     /protein_end="118"
                     /protein_start="104"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LAVLAAGAAYVPVD"
     misc_feature    18940..18954
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.56"
                     /tool="antismash"
     misc_feature    complement(19085..19094)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     tRNA            complement(19138..19225)
                     /anticodon=(pos:complement(7937515..7937517),aa:Leu,
                     seq:gag)
                     /db_xref="GeneID:41543704"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="SAVERM_RS34085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAV_t60"
                     /old_locus_tag="SAVERM_t60"
                     /product="tRNA-Leu"
     gene            complement(19138..19225)
                     /db_xref="GeneID:41543704"
                     /locus_tag="SAVERM_RS34085"
                     /old_locus_tag="SAV_t60"
                     /old_locus_tag="SAVERM_t60"
     gene            19413..20738
                     /db_xref="GeneID:41543705"
                     /locus_tag="SAVERM_RS34090"
                     /old_locus_tag="SAV_6634"
                     /old_locus_tag="SAVERM_6634"
     CDS             19413..20738
                     /codon_start=1
                     /db_xref="GeneID:41543705"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103705.1"
                     /locus_tag="SAVERM_RS34090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6634"
                     /old_locus_tag="SAVERM_6634"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_010988035.1"
                     /transl_table=11
                     /translation="MSESNTARGISGEDEVVDLCRELIRIDTSNYGDHSGPGERKAAEY
                     VAEKLAEVGLEPQIFESHQGRASTVARIEGEDPSRPALLIHGHTDVVPANAADWTHHPF
                     SGEIADGCVWGRGAVDMKDMDAMTLAVVRDRLRTGRRPPRDIVLAFLADEEAGGTYGAK
                     YLVQKHPDLFEGVTEAIGEVGGFSFTVNEKLRLYLVETAQKGMHWMRLTVDGTAGHGSM
                     TNDDNAITELCEAVGRLGRHTWPVRVTKTVRSFLDELSDALGTELDPENMDETLAKLGG
                     IAKMVGATLRNSAAPTMLGAGYKVNVIPGQATAHVDGRFLPGHEEEFLADLDRILGPRV
                     KREDVHGDKALETDFDGRLVDAMQSALSAEDPIAKAVPYMLSGGTDAKSFDDLGIRCFG
                     FAPLKLPPELDFAGMFHGIDERVPVDGLKFGVRVLDRFIDAS"
     misc_feature    complement(20794..20808)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.72"
                     /tool="antismash"
     misc_feature    complement(20804..20824)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.08"
                     /tool="antismash"
     gene            20905..21138
                     /db_xref="GeneID:41543706"
                     /gene="chpH"
                     /locus_tag="SAVERM_RS34095"
                     /old_locus_tag="SAV_6635"
                     /old_locus_tag="SAVERM_6635"
     CDS             20905..21138
                     /codon_start=1
                     /db_xref="GeneID:41543706"
                     /gene="chpH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977150.1"
                     /locus_tag="SAVERM_RS34095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6635"
                     /old_locus_tag="SAVERM_6635"
                     /product="chaplin ChpH"
                     /protein_id="WP_010988036.1"
                     /transl_table=11
                     /translation="MIKKVVAAAAATGGLVLAGAGLAVADSGAQGAAVHSPGVVSGNVI
                     QVPVHVPVNVCGNTVSVIGLLNPAFGNTCINK"
     gene            21234..22145
                     /db_xref="GeneID:91294939"
                     /locus_tag="SAVERM_RS45430"
                     /old_locus_tag="SAV_6636"
                     /old_locus_tag="SAVERM_6636"
     CDS             21234..22145
                     /codon_start=1
                     /db_xref="GeneID:91294939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018570376.1"
                     /locus_tag="SAVERM_RS45430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6636"
                     /old_locus_tag="SAVERM_6636"
                     /product="chaplin"
                     /protein_id="WP_010988037.1"
                     /transl_table=11
                     /translation="MRQVTRKGLMTVAAATGVLAATGGYAHADSGAYGSASHSPGVLSG
                     NSVQVPVHVPVNVCGNTVNVVGLFNPAVGNQCANGGGGGHHDGGGHHGGGGHHGGGYGD
                     SPSGGGGHHGGGGHQGGGYGDGPSGGGGGGGGSQAGGHTGDSPGVGSGNHVQVPVDVPV
                     NVCGNNVTVGGLGNAAGGDACADTPGGGHATTPPGGGGGTTPPGGGGGGTTPPGGGGGG
                     TTPPGGGGGTTPPGTPGHPGQPGGDSSAHPNHPGGQSVTQPEGTAQLAHTGSDMPLGLL
                     VPAGAGALLGGALLYRRARSAA"
     gene            complement(22251..22439)
                     /db_xref="GeneID:41543708"
                     /locus_tag="SAVERM_RS34105"
                     /old_locus_tag="SAV_6637"
                     /old_locus_tag="SAVERM_6637"
     CDS             complement(22251..22439)
                     /codon_start=1
                     /db_xref="GeneID:41543708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006135970.1"
                     /locus_tag="SAVERM_RS34105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6637"
                     /old_locus_tag="SAVERM_6637"
                     /product="DUF5703 family protein"
                     /protein_id="WP_005319466.1"
                     /transl_table=11
                     /translation="MPEYEFVDVYVPRGVSRKEATRLLTDHAEYGHWELDRLSLHRDGS
                     RRVRLRRRIIRQVRATW"
     misc_feature    complement(22470..22488)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            22487..23197
                     /db_xref="GeneID:41543709"
                     /locus_tag="SAVERM_RS34110"
                     /old_locus_tag="SAV_6638"
                     /old_locus_tag="SAVERM_6638"
     CDS             22487..23197
                     /codon_start=1
                     /db_xref="GeneID:41543709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294233.1"
                     /locus_tag="SAVERM_RS34110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6638"
                     /old_locus_tag="SAVERM_6638"
                     /product="hypothetical protein"
                     /protein_id="WP_010988038.1"
                     /transl_table=11
                     /translation="MSDAAQSTAAEVRAAAEAVKTALDRHLAAVERRSGEDDPAVYEAF
                     NELAAAAEEYDELLYDRYDEVTPFEIPGTDDSLPPYTGPEEPSAVSVLIRRDYAVVEPQ
                     RLLAQAQRVEAAEEPADEVAGTVHGALGVLFEEYEPDEIASRHKEFGLEEGDSTLWVTA
                     EEERPEPGEWLEAPFEQIDPQHIVCRFDASAVYDEESDGEESDGEVPEDDLGPDSELDG
                     ELDEDDLEPLDADR"
     gene            complement(23330..25630)
                     /db_xref="GeneID:41543710"
                     /locus_tag="SAVERM_RS34115"
                     /old_locus_tag="SAV_6639"
                     /old_locus_tag="SAVERM_6639"
     CDS             complement(23330..25630)
                     /codon_start=1
                     /db_xref="GeneID:41543710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294239.1"
                     /locus_tag="SAVERM_RS34115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6639"
                     /old_locus_tag="SAVERM_6639"
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_042493873.1"
                     /transl_table=11
                     /translation="MTTEPETTDEAEPGQPGAGAGEVEPGQPGAGAVDGVPETEGTPGS
                     GAAGDAESSAEGTAGSEAAGATESSEGTAGSEAAGTAEGSGDAAKPTEAEAELAAQRVE
                     RERIERRKAEKQAPIEAGTKLSGTAADLLAAVRVVESGAKPVASAFSEPPAPRRPAPEP
                     ERRPEPVAAPAGPAVPAAQAVAGVRAVLTEGGAPEALAPQLAALLGDGADLQLREDPWQ
                     LLRVSGVRPEQADGFARALLGAECGPDDERRGRAVTVWLLEQAALAGHTALEVAALTTA
                     LAQRAVPDPDTAVQSALAEGEVLVFQDALDAAAPAAEAEAEEEGAERPVRVLIGLERYA
                     LAEESLADALGRVMNSVPKEDGSAADWERAAASAGGSAAELIRAVAGHGLVLHTGGDAS
                     GAEAAALLSAARGLGLRTWAAAHSRIGCDRFTARLAPSDLPGGPQQGPGTGVSTVAGLL
                     SGAEGPGRDADGALVLDLLVVLDAPQLDVETAAMLAESLPDGARLVLSGDPGVLWSAGP
                     GRVFADLLAARVCPGIASRTPDPGPIGELISGIGVGELNQVEAPGKEVVIVPVRDAGEA
                     VHRTVQLVADSVPRALGVPAEQTQVITPGHGGAAGTRALNAALKERLNPGPGRFGGFDP
                     GDRIAYSPAPGRTLPGRVVKADADGLHLEIPGAPVVVPKERVEQCVRHGWALTAHQAVG
                     SRWPAAVVVLPGDAAQSLTRPWVYTAFGLAERHLSVVHGVEQALPRAVAEVTAKPRTTR
                     LPALLRPQVPAAD"
     gene            complement(25627..26610)
                     /db_xref="GeneID:41543711"
                     /locus_tag="SAVERM_RS34120"
                     /old_locus_tag="SAV_6640"
                     /old_locus_tag="SAVERM_6640"
     CDS             complement(25627..26610)
                     /codon_start=1
                     /db_xref="GeneID:41543711"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607539.1"
                     /locus_tag="SAVERM_RS34120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6640"
                     /old_locus_tag="SAVERM_6640"
                     /product="aldo/keto reductase"
                     /protein_id="WP_010988040.1"
                     /transl_table=11
                     /translation="MEQRHLGRTGLRVSRIGLGTLTWGRDTDEHDAAELLKVFWEAGGT
                     LVDTADVYGDGEAEYVLGQLIEGLVPRRDLVISTKAGSVADPDRRFDGSRGHLLSALDA
                     SLARLGTDYVDLWQVHAFDPHTPLEETLQALDLAVSTGRARYAGVSNFCGWQLAKAATW
                     QLSAPGPRTRIASTQMEYSLLQRGVEREVLPAALDLGVGLLPSSPLGRGVLTGKYRGGT
                     PAGSRGASEHLAPFVAPYLDDTASGIVDAVQTAADGLAVTPLQVALAWVRDRPGVAAPI
                     VGARNAQQLTAALSVETLSLPDEICRALDDVSAPVHHYPDQDWSTL"
     gene            26764..27819
                     /db_xref="GeneID:41543712"
                     /locus_tag="SAVERM_RS34125"
                     /old_locus_tag="SAV_6641"
                     /old_locus_tag="SAVERM_6641"
     CDS             26764..27819
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543712"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002496.1"
                     /locus_tag="SAVERM_RS34125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6641"
                     /old_locus_tag="SAVERM_6641"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_010988041.1"
                     /transl_table=11
                     /translation="MQLGINLGYWGAGMDADNLAVAQEADRLGYGVCWAAEAYGSDAAT
                     VLTWVAAQTERIDVGSAIFQIPARQPAMTAMTAATLDSLSGGRFRLGLGVSGPQVSEGW
                     YGVKFDKPLARTREYVEIVRKAMTRERLSYQGEHWTLPLPDGPGKPIKLTVHPEREYIP
                     VYIAAIGPKNLEQTGEIADGALLIFPSADHLEDTAIKHLRAGREKAGKTMDGFDVCPTL
                     PLALGDDKNVTALADTFRPYTALYVGGMGSRKQNFYNQLAQRMGYEKEAAEIQDKYLSG
                     DKEGAAAAIPHELIDQTTLLGSVDRIADRMKAYAAAGVTTLTLAPAGFTLEERIAALRA
                     GTDALERAGLA"
     gene            28045..28833
                     /db_xref="GeneID:41543713"
                     /locus_tag="SAVERM_RS34130"
                     /old_locus_tag="SAV_6642"
                     /old_locus_tag="SAVERM_6642"
     CDS             28045..28833
                     /codon_start=1
                     /db_xref="GeneID:41543713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015661622.1"
                     /locus_tag="SAVERM_RS34130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6642"
                     /old_locus_tag="SAVERM_6642"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_010988042.1"
                     /transl_table=11
                     /translation="MLSVRSLFQEILDNDESFRLFCSIAASGESQGGWENGRIAALVPH
                     SQRDLAPKITRHGADEDKHGRIFHALMKKRGLDPVAIPPDTDYTMLLERHGIGLAHEKL
                     KGDEPLTVQDIVTYLAHSRVTEQRAAEQMELLRRHFADHPDIGRAVRMISHDEDNHLAY
                     CHEELLRFAYTGHGRAIQRTLRQCALAEIRVYRDVSLAVMAHMGRLLGWPKARAAALAA
                     GIHAVYAYERAVGWRRMVSLRMPERRDALGGPATTAAEYA"
     misc_feature    28086..28100
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.19"
                     /tool="antismash"
     gene            complement(29021..30016)
                     /db_xref="GeneID:41543714"
                     /gene="corA"
                     /locus_tag="SAVERM_RS34135"
                     /old_locus_tag="SAV_6643"
                     /old_locus_tag="SAVERM_6643"
     CDS             complement(29021..30016)
                     /GO_function="GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543714"
                     /gene="corA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002498.1"
                     /locus_tag="SAVERM_RS34135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6643"
                     /old_locus_tag="SAVERM_6643"
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="WP_037646435.1"
                     /transl_table=11
                     /translation="MIVDCAIYRDGRRTEGPEDLSDALDEARAQGDSFLWIGLHEPTEK
                     EFDLVTHEFGLHPLAVEDALKAHQRPKLEVYDDSLFVVLKPVTYEPYSDTVSSGEVMVF
                     VGDSFVVTVRHGEGAPLSSIRHELERRPDMLRHGPTGVLHAIADSVVDHYLDVATELGT
                     DLEELEAEVFSPSGGARNTASRIYSFKRQIQEFRRATVPLTPPLTRLAGLGPNLAAVPF
                     VKEEARPFFRDVNDHLTRVNESVEGLDRLVSDILSAHLAQMSVRQNDDMRKISAWAAMA
                     AIPTMIAGIYGMNFEHMPELHWTWSYPAVIAAMVVLEVLLYRLFKQRGWL"
     gene            30115..30801
                     /db_xref="GeneID:41543715"
                     /locus_tag="SAVERM_RS34140"
                     /old_locus_tag="SAV_6644"
                     /old_locus_tag="SAVERM_6644"
     CDS             30115..30801
                     /codon_start=1
                     /db_xref="GeneID:41543715"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128286.1"
                     /locus_tag="SAVERM_RS34140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6644"
                     /old_locus_tag="SAVERM_6644"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_037646439.1"
                     /transl_table=11
                     /translation="MPTLILVRHGRSTANTAGLLAGWTPGVALDERGAAQAAALPGRLA
                     EVPVSEIVTSPLQRCRETVQPLLDARPGLRAHTEERIGECHYGDWSGRKLAELKDEPLM
                     EVVQSHPSAAAFPGGESMRAMQTRAAEAVREWNARVERDHGSDAVYLMCSHGDIIKSLV
                     ADALGLHLDLFQRISVEPCSITAIRYTRLRPFLVRLGDTGDFASLAPREEPSGGDAPVG
                     GGAGAP"
     gene            30912..31502
                     /db_xref="GeneID:41543716"
                     /locus_tag="SAVERM_RS34145"
                     /old_locus_tag="SAV_6645"
                     /old_locus_tag="SAVERM_6645"
     CDS             30912..31502
                     /codon_start=1
                     /db_xref="GeneID:41543716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447870.1"
                     /locus_tag="SAVERM_RS34145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6645"
                     /old_locus_tag="SAVERM_6645"
                     /product="DUF3090 domain-containing protein"
                     /protein_id="WP_010988045.1"
                     /transl_table=11
                     /translation="MSRQVFLYDPPDRFVAGTVGLPGRRTFFLQASSGPRVTSVALEKT
                     QVAALAERMDELLDEVVRRSGGSAPVPAMAPTEISDNAPLEAPVEEEFRVGTMALAWDG
                     DEQRMIVEAQALVELDAESDEDLAEAEERLLQDEENGPPMLRVRLTGLQARAFAKRALD
                     VVNAGRPPCPLCSLPLDPEGHVCPRQNGYRRGA"
     gene            31466..32284
                     /db_xref="GeneID:41543717"
                     /locus_tag="SAVERM_RS34150"
                     /old_locus_tag="SAV_6646"
                     /old_locus_tag="SAVERM_6646"
     CDS             31466..32284
                     /codon_start=1
                     /db_xref="GeneID:41543717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671712.1"
                     /locus_tag="SAVERM_RS34150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6646"
                     /old_locus_tag="SAVERM_6646"
                     /product="SCO1664 family protein"
                     /protein_id="WP_171033150.1"
                     /transl_table=11
                     /translation="MSAPERIPPRSVTTAELLAEGELKVRGRIREASNAALYCTVSHDG
                     QEAFCIYKPVAGERPLWDFPDGTLAQREVAAYEVSEATGWGLVPTTVLRDGPYGEGMCQ
                     LWIEGQPDVELLALVDGEEPEAGWKAIGFADVGEGRTALLVHADDERLRRLAVLDAVIN
                     NADRKGGHLLPTDEGRLYGIDHGVTFNTENKLRTLLWGWAGEPLTADAAEALGTLKDGL
                     TAGGALATRLAELITPAELDATRARVDAMLTSGKHPEPSGEWPAIPWPPV"
     misc_feature    32419..32437
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.83"
                     /tool="antismash"
     gene            32437..33666
                     /db_xref="GeneID:41543718"
                     /gene="mshC"
                     /locus_tag="SAVERM_RS34155"
                     /old_locus_tag="SAV_6647"
                     /old_locus_tag="SAVERM_6647"
     CDS             32437..33666
                     /EC_number="6.3.1.13"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41543718"
                     /gene="mshC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933383.1"
                     /locus_tag="SAVERM_RS34155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_6647"
                     /old_locus_tag="SAVERM_6647"
                     /product="cysteine--1-D-myo-inosityl
                     2-amino-2-deoxy-alpha-D-glucopyranoside ligase"
                     /protein_id="WP_010988047.1"
                     /transl_table=11
                     /translation="MHAWPASEVPALPGEGRDLRIHDTATGGVIPLHPGPVARIYVCGI
                     TPYDATHMGHAATYNAFDLVQRVWLDTKRQVHYVQNVTDVDDPLLERAERDGVDWVGLA
                     EKETALFREDMTALRMLPPQHYIGAVEAIPGIVPLVERLRDAGAAYELDGDVYFSVEAD
                     PHFGKVSNLDAAAMRLLSAERGGDPDRPGKKNPLDPMLWMAAREGEPSWDGASLGRGRP
                     GWHIECVAIALDHLGMGFDVQGGGSDLAFPHHEMGASHAQALTGEFPMAKAYVHAGMVA
                     LNGEKMSKSKGNLVFVSKLRRDGVDPAAIRLALLAHHYRSDWEWTDAVLEEALARLGTW
                     RAAVSRPDGPPAEALVEEIRDALANDLDAPAALAAVDRWAALQHERGGTDEGAPGVVSR
                     AVDALLGVAL"
     misc_feature    33817..33834
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
ORIGIN
        1 ttccgtgcga attcgatcac gcgctggacc ctacggtatg accgcgccgc cacgtccggc
       61 acggcggtcg tccgtccggg cccgccccca cctggccgga cgcgctcgcc cgacgacgtc
      121 agcccgtggc gcgatgcgcc ttgagccgct cgtacgccgc gagcccgtcc gggacccact
      181 cccagtcggc cagccggcgc tccacctcgt cctggggcag gaagtcgtgc caggcgacct
      241 cctccacctg ggggctgacc gggaggtcgc agcggacctc gtagaccgac gaccaccagg
      301 tctggccggc gccgttgtcg tacaggaact tgaagagggg ggccgggcgg ggcagaccgc
      361 agacgccgag ttcctcctcg gcctcgcgca gggccgcgtc gtcgtacgtc tcgcccgcgc
      421 cgacgactcc gccgacgaac atgtcgtaca aggaggggaa gaccagcttg gtgggcgtcc
      481 ggcggtggac gaagatccgc ccctcgccgt cccgggccag gatgaacacg caccggtggc
      541 gcagcccccg cgcgtacgcc tccccgcgcg ccgactgccc gacgaccctg tcgttctcgt
      601 ccacgatgtc gaggagttca tcggcggggt cgacggggcc acccgtcggt ccgctcgtcg
      661 ctccgctcac ggctgcttcg gtcacggctt cgctcacggg ttcgctcatg ggcccatcca
      721 agcagggccg ggcccgggtc ctcgggggcc cggctcctca atgcggctgg agatcccgct
      781 gccgctccgc ctccgcggag ccccgcggca tcgccgggtg cagtccgagg aggacgatgc
      841 ccagcacgac cgccgcgagc cccgccgcct cccaggcgag cgccccggtg tccgtgcgca
      901 gctggtcgcc gaggaagccc accccgcaga cgattccggc cagcggctgg gccgcggtga
      961 gggccggcag ggacatccgc agcggcgccg tctcgaacgc gctctgcacc agcaccagcc
     1021 cggtcacacc gagggccagc accgcgtacg gctgccagcc ggtgaccagc tccggccagc
     1081 cgccctcgct gaaccgctgc ccgctgaccc gggtgagcgc gtcctgcacg ccgtacagca
     1141 ggcccgccgc gagcgacagg agcacggggg cggcgctcag ccgcgactgc ttcgcgtagg
     1201 tcgtcagcag cagcgcgaac ccgaccatca cgccgatgat cacccagtgc cgtaggggat
     1261 tcgtgaccgc gtcgccgccg gtcggctggc cggcgacgat gaacgccgtg acgccgcccg
     1321 cgagcagcgc gagccccgcc cagccctggc gtcccagcgg ctgcttggtc tgccggcggg
     1381 agaggcccag cgcgaagagc aggttcgtgg cgagcagcgg ctcgaccagc gacagctcgc
     1441 catgggccag ggcgaccgca ccgagcacca tgccgaccac catgaacccg atgccgccga
     1501 gccagcgccg cacatgcatc aggtccagga gcagtctggg cgagaggaag tcgctcagcg
     1561 gagcatgctg ggccgcgttc tgctggagca cgaacccgat gcccaggcag aaggccgcgc
     1621 tcacggcgag aaccagaacc agtaccgaca cgctgcgtac ctcgaaactc agcggggcca
     1681 cgggatgcgc cgactgtagc gctccccgct gtgagttgcc gtgagagtac ccacaacccg
     1741 gcagttgact cgctcactct tgtaccgaag gatctgaccg atcagtaaca acgtaccgac
     1801 tggtggtcat gccggaccgg ctcgcggtcg tggctgctcg gtcatgtcga gaggacgggc
     1861 gaatggccca cgacgcagac gtcatcgtga tcggcgccgg cctggcaggg ctcgcggcga
     1921 ccgcggagct ggtggacgcg ggccgcaagg tgatccttct cgaccaggag ccggagcagt
     1981 cgatgggcgg ccaggccttc tggtcgttcg gcgggctctt cttcgtcgac tcgcccgagc
     2041 agcgccgtct gcggatcaag gacagccacg cgctcgccct ccaggactgg atgggaacgg
     2101 ccggtttcga ccgtcccgag gaccactggc cgcgcaagtg ggccgaggcg tacgtcgact
     2161 tcgcggccgg tgagaagcgg gcctggctgc accggcaggg ggtgcgcttc ttcccggtgg
     2221 tcggctgggc ggagcgcggc ggctacgacg ccaacggaca cggcaactcg gtgccgcgct
     2281 tccacatcac ctgggggacc ggacccgggc tgatcgagcc gttcgtgcgg cgggtgcggg
     2341 cgggggtcgc gcggggactg gtcgagctga ggttccgcca ccgggtcacc ggtctgtcgc
     2401 gcagcgcggg cgccgtggac accgtcacgg gtgaggtgct ggaggcgtcg gacatccagc
     2461 ggggccgggc cagcagccgc gaggtcaccg gagccttcga gctcacggcc caggcggtga
     2521 tcgtcacctc gggcggcatc ggcggcaacc acgacctcgt ccgcgcgaac tggccggagc
     2581 ggctgggcag ggccccggag aagatgatct cgggtgtgcc cgcgcacgtc gacggcagga
     2641 tgctcgccat cgcggagggg gcgggtgcgc gtctgatcaa ccgcgaccgc atgtggcact
     2701 acaccgaggg catccagaac tggaacccga tctggcacaa ccacggcatc cgcgtcctgc
     2761 ccggcccgtc ctccctgtgg ttcgacgccc gcggcaaccg gctgcccgtg ccgctcttcc
     2821 ccggcttcga cacgctcggc acgctcgaac acatcatgaa gaccgggtac gactacacgt
     2881 ggttcgtgct cgaccagaag atcatcggca aggagttcgc cctctcgggg tccgagcaga
     2941 accccgatct gacgggcaag tcgatcaagg acgtgatcgg gcgggcgcgg gccgaggtgc
     3001 cggggccggt gaaggcgttc atggaccacg gtgtggactt cgtcgtggag aaggacctgg
     3061 gcgcgctggt gcgcggcatg aacgcgctga ccaaggaacc gctcatcgac gaggccgcgc
     3121 tgcgccgtga gatcgtcgcg cgcgaccggg agatagcgaa ccccttcacc aaggacctcc
     3181 aggtgacggc gatgcgcggg gcccgcaggt tcctcggcga caagctgatc cgcacggccg
     3241 ccccgcaccg catcctcgac cccaaggcgg gtccgctgat cgccgtgcgc ctcaacatcc
     3301 tcacccgcaa gacgctcggc ggcctggaga cggacctctc gtcgcgggtg ctgaccgagg
     3361 gcggcgcccc gctggagggc gtgtacgcgg ccggcgaggc cgccgggttc ggcggcggcg
     3421 gcgtccacgg ctaccggtct ctggagggca cgttcctggg cggctggctg ttctcgggcc
     3481 gcacggtggg ccgggcggcg gcacaggccg tgggctgaga cgcgggccag ggtgcgggcg
     3541 gtggactgag gcgggccgga cctgggtcgt gggccgggtc cgaggggctt cggcagcacc
     3601 tcccgcgccc gcctgcccgc gaccgccgcg cccgcctgcc cgcgaccgac ggcacgcgga
     3661 actcaggcgg tggccggtgt ccggtgtccg gtggcgtgcg ccccgcgctc gcggcgtgtg
     3721 gcggcccggt gtccgaaagg agcgccggac gccgccagac gcacggtgta ctgacggtgg
     3781 ccgtatgcca agcgctctcg gcgcacggcg accgtctacc gcccgactgc cgtccgcagc
     3841 acagtgcccc gcacccgtca agtcgcctgc accaaaggca cgttgacacg tgtaggcccc
     3901 tgggtgccct tgactggaag cgttggctga gggtttgctg tccgtgatca gttactgaca
     3961 aaccgcgccc tgtgaggaac ccccgcggtg cccccacccc cacccccact cggccgtggt
     4021 cgcaagcgtg cggcccatgc cttcgacgcg gcgctcgacg acgccgaact cgtcgcctcc
     4081 cgcgcctcgt tgacccaggg gcgatgggcc cccgtgcgcg cgctgctcgc cgcgacccgc
     4141 gacgactggg accgtcgggg acaccgcgtc accgtcctgg cgcaggagtc cgccgccctt
     4201 ccctgggcgc gcgaatggca gctcgccgaa cccgagtccc cctgcgccgc cgtactgctc
     4261 gcctgcgcca ccgtccaccg cgccctgaac ggcaaggagc gcccgcagac ggcacgcgag
     4321 gcctgccacg ccgcggccgc cctcgccccc gacgacccca caccgtggct cggcctgctg
     4381 atactggagc gctcactcgg caccgacgag gacgtggtcc gcctcttcga cgaggtccgc
     4441 caccgctgcc ccgaccacca ccacgcccac cagctcatcg tcgcccggct cgccgaacgc
     4501 cgcgcggacg ccggacggga cccgctgcac gaggtctacg acttcgccaa ctgggccgcc
     4561 gaacaggccc ccgccgactc gccgctcgcg atcctcccgg tcgtcgcgca cgccgagcgc
     4621 taccgcgtcc tcgccgccgc cggtgccgag cccgccgacc cggtcgcctc cgggcactgg
     4681 gtggggcggc gggcccgcca ggtgatgaag gccgccttcg actggtggct ggagtgggag
     4741 cgcgacgacc atccgcgccg cttcgtcgac ctcaacttcc tggcccacgc caagttctgc
     4801 gagggccgtg gcgccgaggc cgccgccctg ttccaccgca tcggagaaca cgccaccccg
     4861 gcgccgtggt cgtacccgga ccgcgacccg taccaagcct tcagcgccgc acgcgccagc
     4921 gcgctcggcg ccccctgaac ggccgccggc cgtcggcccc cgaccgccgg cccccgagac
     4981 atcacctcgc accccagccg agacatcagc cgagacatcg gccgagacac cagtggagag
     5041 gacaaccccg ccatgacgac gggcagttcg agcacgagtg agagcagacc agcgaacagg
     5101 tccgccgtcg cggacgacat cagcaccttc aagggacagg aacgcgctct gcgcgccgac
     5161 cggctcggca cggcgggcct gttgctgtcc gtgctcgccg cgaccgcccc tctcatggtg
     5221 gtcgcgggtg tcatgcccac tacattcggg gtcatgggca tcgtcggcca gcccctgctc
     5281 ttcgtcgtcc tcggcgcggt gctggccctc ttctccctgg ggtacgcgga gatgagccgc
     5341 cacgtccaca acgcgggcgc cttctacgcc tacatctcgc gcggcctcgg cggcacggcg
     5401 ggcgcgggtg ccgcggcggt cgcactcgtc gcctacagcg cgctccagtt cgccatctac
     5461 ggcatcttcg gcttcgaggt ctcgggtctg tgcgccacct acctcgaact ccaggtcgcc
     5521 tggtggatcc cggcgctggc ggccgtcctc gccgtcggcg cgctcggcct gctgaagatc
     5581 gacgtcaacg cgcgcgtgct cggcgtgctg ctgctcatcg aggtcgtcct cgtcgtcgtg
     5641 ttcgacatcg cggcggtcgc cgaccccgcc aaggaaggcc tgtcgctgca cgccttcaac
     5701 ccggacaccc tcaccggtgc gggcgtcggc accgcgctct gcttctgcgt cgccgccttc
     5761 ctcggcttcg aacaggcccc cgtctacgcc gaggagacca gccgcccgga cgtcctcgtg
     5821 ccgcgcgtga tgttcctcgc gatcggcttc gtcgccgtct tcttcgcggt cagctgctgg
     5881 gcgttcacgg tcgccgccgg tccctccacc atcgtggccg ccgcccagaa acagagcgcg
     5941 ggcctgctct tccagctgac ggagtcccgg ctcggcggca ccttcaccga cgtactgcac
     6001 gtgctcttcg tgaccggcat gttcgcggcg atgctcagct tccacaacgt ggtcgcgcgg
     6061 tacgccttcg cgatgggccg cgagggactc ctgcccgccg ccttcggccg tacgacgggc
     6121 gcgagcggcg cccccggtac gggctcgctc cttcagacgg ccgtgtcggc ggtgatcgtc
     6181 atcgccttcg cgatggccga cgacaagccg gccggcgacc cgaccgcgcc cgtgctgcac
     6241 ctgttcacct ggttcggcag cgtcggggcg ctcggcgtca ccctgctgat ggtggcggcc
     6301 tccctgtccg tgatcgtctt cttcgcccgc cgcggcgccg cccgcgcaca ggcctggcgg
     6361 ctggccacgt ccgcggtgtc gggggccgcg ctgctcgtga tcgtgggcta cacggtcaag
     6421 gacttcggcg tactggtcgg aacgggaccg gactccgcgc tcggctgggt gctcccggcg
     6481 atcatcgggg tggccctggt cctcggcctg gcgcagggac tggtcctgcg ctcccgtaag
     6541 ccccaggcgc atgcccgtat cgggctggac aacgaggcgt tccagctgga caaggcggcg
     6601 gagtcggcga cctgaaccgc gcccccgcgc cgcgatcccg cttcccgcgc acccggcgat
     6661 ccctgaaatc ccggtgagaa gtggttacgg aattctgacg agcacccgtc tgccctggcc
     6721 tcaagggggt ggcgggtgct cgaatcatgg tgtgaaccct gaacatcccg aagagcggga
     6781 agcaccggag cccgagaagc gggaggcacc ggagcccgag gggcggggca ccccgatcgg
     6841 gcgccgggtc ctcctcggca ccctcggcct cggcgcgctc ggtgtcgtcg ccgcgcccgt
     6901 gctccagcga ggaatggagt ccgtcctcgc cggagcggcc gagaaggacc cgacgggcct
     6961 gaccggtctg ctgcccaacg gcgggggctt tcgctactac tcggtgacgt cgtcggtccc
     7021 gcacaagggg gaggcgaact accgcctcac gatcgacggc ctggtcgacc acccgacgtc
     7081 gttcaccctg gccgatctgc gggccctgcc gcagacccgg ctcgtgcgcg acgtccagtg
     7141 cgtcaccggc tggcgggtgc cggggacgcc gttcgagggc gtacgtctgt cccggctgct
     7201 ggacgcggcg ggcgtccgct cctccgccag ggcggtccgc ttcacctgct tcgacggggc
     7261 gtacaccgag agcctgacgc tcgcgcaggc ccgccgcgcg gacgtcctgg tcgccctgcg
     7321 catgcaggac aagcccctgg gccacaacca cggcggcccc gtccgcctgt acgtcgcccc
     7381 catgtacttc tacaagtccg ccaagtggct ctccggcatc accgtcaccg aggacgtccg
     7441 tcccgggtac tgggaggacc ggggatacga cgtggacgcc tgggtgggca agtcgaacgg
     7501 gcgggacgat gaccctacga gctgacgccc ccgcccccgc cgtgtcctca cgggtacggc
     7561 gcttcacgcg cgcggagcgc tgggtgcacc gggtgacggc cgcgctgatg ggcgtgtgcg
     7621 tggtgacggc cgcctgcctg tacatccccg ttttcgcgga actggtgggg cgccgggacc
     7681 tggtcgtacg ggtccacgag tgggcggggc tgctgctgcc ggccccggtg ctcgcggggc
     7741 tggcgtcgcg cgcgttccgg tcggacctgg gtcacctcaa ccgctggggc ccgcacgacc
     7801 gggtctggct gcgggcggtc ctgcgccgcg acgcccggcc ctcgtcccgt ccggcggcga
     7861 agttcaatgc gggccagaag acgtatgcgg cgtggatcgc gggagcgtcc ctggtgatgg
     7921 tgggcacggg gctgctgatg tggttcaccc acctcacgcc gctgatgtgg cgcacgtcgg
     7981 cgacgttcgt ccacgactgg ctggccctga cgatcggcgt cgtcctcgcg ggccacatcg
     8041 gcatggccct ggccgacccg gaggcccgcc gcggcctgcg cacgggctcg gtgagccggg
     8101 agtgggccag ccaggaacac cccctgtggc gcgaaggccc tccgggcggg gaccggcggg
     8161 ggtgacgctg cggcgtcctg ttcgtggccg caccgccgaa gaacgcgcgg aacgtcccgc
     8221 cgcgaggggt cccgccgcga caggtatcgc cgcgacaggt actgccacgg cgggtactgc
     8281 cgcgaggggt atcgccgcga caggtatcgc cacggcgggt accgcccacg gcgggtatcg
     8341 ccgcgacagg tactccacgg cgggtaccgc cacgctggcc gtacccggcg gcgccgaacc
     8401 cgccgcgcgc cggcggcggg gacccggtcc cggcccctca gaccccgaag tccagcagca
     8461 ccttgcacgc ctcaccgcgg tccgcggcca gcgcgaacgc cgactccgcc tcctcgagcg
     8521 gaaccaccgc gctgatcagg gagtcgaacg ccggctcacg cgccagcagg gtcagcgcct
     8581 cgtcgaactc gtcggcgaag cggaacgctc cccgcagttc gatctcccgg ctgaccacca
     8641 ggttcccggc gaacggcgtc tgtccgggcg gcagcatgcc cagctggacg accaccccac
     8701 cacgccgcac caggcgcagg caggtgtcaa gacccgcggc aaccccggac gcctcgacgg
     8761 ccacgtcgac cgagtccggc cacccggcgt cggccggatc gtcggcgcgt acgacgtcgt
     8821 ccgcgcccac cccggcggcg tacgacagcg cccgcggcag cagatccgtc accgtcaccc
     8881 gccccgctcc ggcggccttc gccgcggcca ccaccaggca cccgatcggc ccggcccccg
     8941 tcacgagcac cggccggccg gccaccggcc ccgcccgccg taccgcgtgc aacgccaccg
     9001 acagcggctc cgcgagcgcg gcccgccgca gatccagccc ctccggcagc gccctcacct
     9061 gcgcggcggg taccacgacc cgcgcggcga acccgccctg gacgtgcggc atacgggccg
     9121 cgctgcccag atagcgggtg tcccggcaca cgttcgcccg gccgtccgcg cactccggac
     9181 acaccccgca cggcgtcgcc gggtgcacgg ccacggccgt acccggcgcg ggaccggcgg
     9241 ccccgggccc gtacgagagg accgtcccca ccacctcgtg cccgagcacc atcggctccc
     9301 gcagccggaa gtccccgact ccgccgtgcc gccagtagtg caggtcggag ccgcatacgc
     9361 cgccgtaacg gacggcgacc agcgcctgcc ccggtccggc ggccggctcg ggcagttcgt
     9421 cgacccgcag gtcgccccga ccgtggatca cacaaccgag catcgtccgg cctctctaga
     9481 gcacactcgt catgccgccg tcgacgtaca gcacctgccc gctgacgaag tccgccgcgg
     9541 gagaggcgag gaagagcacc ccgccgacca ggtcctccgt acgtccccag cgcccggccg
     9601 gggtgcggtg ccgcacccac gcgctgaact cctcgtcctc gacgagcggg cgggtcaact
     9661 cggtctctat gtagccgggg ccgagcccgt tgacctgcac cccgtacggg ccccagtccg
     9721 cgcacatgcc cttggtgagc atcttcagcg cgcccttggt cgccgcgtac ggggcgatgc
     9781 cggggcggac gacctcgctc tggagggaac agatgttgac gatcttgccg tggccgcgtt
     9841 ccgtcatacg gcgggccgcc tcgcggccca ccaggaacgc gctcgtcaga ttggtgttca
     9901 ggatccggtg ccagtcggag tccgtgaact ccaggagcgg ggcgcgcagt tgtatgcccg
     9961 cgttgttgac caggatgtcg agcggaccca cccgctcctc gacctccgcg atgccggcgg
    10021 ccaccgacgg accgtcggtc acgtcgaacg cggccgtacg gacgtcgccc ggcagttcgg
    10081 cggccgccgc ggtgagccgg tcgccgtccc gtccgttcag gacgaccgtg cagcccgcct
    10141 ccaggaggcc gcgggcgagc gcgcgcccga tgccgcggct ggagccggtg accagggccg
    10201 tacggccggc gatgtcgaag agcggatggc tcattcccgt actcctagat cacgagggac
    10261 agcagcagga ccagtccgcc ggcgaccacc gagatgatgg tctccatgat cgaccaggtc
    10321 ttgaccgtct ggccgacgct cagaccgaag tactccttga ccagccagaa cccggcatcg
    10381 ttcacatggc tgaagaagag cgagcccgcc ccgatcgcca gcacgaggag cgaggtgtgc
    10441 gcggtcgaca tgtcggccgc gaggggcgcg acgagaccgg ccgcggagat ggtcgcgacc
    10501 gtcgccgaac cggtcgcgag ccggatcgcc accgcgatca gccaggccag cagcagcgcc
    10561 gggatcgacc agtccttgga gatctccagg atcatctggc ccacaccgga gtcgatcagc
    10621 gtctgcttga agccaccgcc cgcgccgacg atcagcagga tgcccgcgat cggggcgagg
    10681 gacttctcga cggtcgtcga gaggcgctcc ttggtgaagc cggccgcgcg gcccagcgtg
    10741 aacataccga cgatcacggc cgcgagcagc gcgatcagcg gtgcgccgat gacgtcgaag
    10801 acgcgctgca cctggtgcgt ggggtcgtcg acgatgatgt cgaccagggc ctttgccagc
    10861 atcagcacga ccggcagcag catggtggcg agggtggcgc cgaagccggg gcgcttgtcc
    10921 aggtcctcgg aagcgcgggt ggggatcatg cggtcgggag ccggaacgtc cacccagcgg
    10981 gctgcgtatt tcgagaacac cgggcccgcg atgatcaccg tcgggatggc gacgaggaca
    11041 ccgagcgcca gcgtgaggcc gaggttcgcc ttgaccgcgt cgatcgcgac cagcgggccg
    11101 gggtgcggcg ggatcagccc gtgcatcacg gacaggcccg cgagcgccgg gatgccgatc
    11161 cgcatcagcg agtagttgcc gcgcttggcg accatcagca cgaccgggat gagcagcacg
    11221 atgcccacct cgaagaacag cggcaggccg atcacggagg cgatcagcac catcgcccac
    11281 ggcatggccc gcccgcccgc cttcgcgagg atcgtgtcga cgatctggtc ggcgccgccg
    11341 gagtcggcga gcagcttgcc gaggatggcg cccagcgcga tcaggacgcc cacaccggcg
    11401 acggtcgagc cgagcccggc cgtgaagctg acgatggtct tgtcgagcgg cgccccggcg
    11461 aacgcgccga gcgcgagcga accgatggtc agggcgagga acgcgtgaag cttgaacttg
    11521 gtgatgagca gcacgatgac ggcgatgccc gccagtaccg cgatgccgag ttgagcgtgg
    11581 cccgccgagg tgatcggttc gacggtgtcc gctgccagct tctcgacgct gagtctggtc
    11641 acgggtgggt cccttgtgtg tgaagagtgg ggagaagagg gggatgagag gaactgcgga
    11701 gagtaagtac tgagcggaag taccgagcgg aagcgccggg ggcttacttc gccggctgag
    11761 aggccggttc gagggcccgc agcgccgtca cggcccgctc gctgatctcc tcgggaccgc
    11821 cggtgacatc cacggcgacc ccggcctcgt ccgccgccag cggctgaagc gtggcgaact
    11881 gcgagtccag cagcgccgtc ggcatgaagt gcccctgccg gtgcgacatc cggtcctcga
    11941 tcagctcgcg gtcgccggtg agatgcacga agacgacgcc gggcgccgcg gcccgcagcc
    12001 ggtcgcggta cgaccgcttc agcgcggagc tgctgaccac tccgccgagc cccgcccggc
    12061 tgtgcgccca ggcgccgatc gcgtccagcc agggcaggcg gtccacgtcg tccagcggca
    12121 ctccggccga catcttggcg atgttggccg gggggtggaa gtcgtcaccc tcggcgtagg
    12181 gaacgccgag ccgggcggcg agcagcggac cgatcgtggt cttgcccgtc cccgcgacgc
    12241 ccatcaccac gactacgtgg ggggtgtgca cctgttccat cactgctctc gctgtcttcg
    12301 tcgacatctg atgtcgacca cactgaaacc gattaggtac gacgaattca agagtctgtg
    12361 acaaataagt ctgacttttt gtgccagtga tccacctcgt actctgagtg catgaccaca
    12421 ccgggccggg ggctgcacgg ccatgtactg gagaccctcg ggcccgccat cgccgcgggc
    12481 acctacccac cgggaagcgt gctgcgcacg gacgagctcg cccagcgctt cgaggtctca
    12541 cgctccgtga tgcgcgaggc ggtccgcgta ctggagtcga tgcacctggt ggagtcccgc
    12601 cgccgcgtcg gcgtgacggt ccgtcccaag gccgagtgga acgtgtacga cccccaggtc
    12661 atccgctggc gactggccgg cgccgaccgc ccgcaccagc tgcgctcgct gaccgtgctg
    12721 cgttcggcgg tcgaaccggc cgccgcgggc ctggccgcac ggcacgccac cgccgatcag
    12781 tgcgcggacc tcaccgagtg cgcgctgggc atggtcgcca cgtcccgcgg ccatcagctg
    12841 gaggcctatc tggtccacga cgtggccttc caccgggtga tcctcaacgc gtcgggcaac
    12901 gagatgttcg cccgcctggg tgacgtcgtc gcggaggtcc tggcgggccg cacccaccac
    12961 gaggtcatgt tcgaggaccc cgacccggcc gccgtcacgc tccacgtcca ggtggcggag
    13021 gcggtacgcg agggcgacgc cctccgcgcc gagcagctca cccgtgagat cacggtcggc
    13081 gccctccagg aactggacat cctggcgccg tagccacccg gcggttactc gaagaactcc
    13141 ccgtcgacgt acacccacgc cccgccgatc cgctcgaacc ggctccgctc ctggagcgca
    13201 ccgccccggt aggacgcccg gaacgtgacc gtcccggccg agtggaacgc ggacccctcc
    13261 gtcgtcccca ggatctccag gccggtccac cgcatccgcg ggtcgaagtc gacctcggcg
    13321 ggccgcgtcc gcggatgcca ggtccgcagc agatacgcct cgtcccgccg cacgaaggcg
    13381 cagtaccgcg accgcatcag caacgcggcg gtgggtgcgt cggcggcacc ggagtggaac
    13441 cgcccgcagc acgcctcgta cacctcggga agcccgcacg gacacgaagc cggctgcggg
    13501 cgcgacgtgg ggcgcgaagt ggaacgcgta cgacgggact tgctcatgcg gaccccgtaa
    13561 tgtgcggcgg atacggcgga cgcgccggta ccggcgcggc gaggacgggc agcgacggca
    13621 gggcggtctc ctccagccac gcggtgaaca gctcgtccag cggctgggcg gagaagcgcg
    13681 cggcatgcgt ggtgaacgcg gcggtggtca ccaccccgcc ccggtgcaca cccgcccacc
    13741 cgcgcagcat ccggaagaac gcctcgtcgc ccagcgcaca gcgcaccgcg tgcagcacga
    13801 gaccgccgcg ctcgtagagc cggtcgtcga acatcagctt gcggcccgga tcggccagcc
    13861 gcagatcctg cggcagcgag gacagcttcc ggtgcgcgag cgtggcgagt tgctgtgccg
    13921 tacggccgcc ggagcgctcc gaccacagcc actcggcata cttcgcgaac ccctcgttga
    13981 gccagatgtg ccgccagtcg gcgatggtca cgctgttgcc gaaccactgg tgcgccagct
    14041 cgtgcgcgac aagccgctcc gaaccccgct tcccgtccac gtggttggcg ccgaacaacg
    14101 acaacccctg tgcctcgacg gggacatcca gctcctcctc cgtcacgacc accgcgtact
    14161 cgccgaacgg atacggcccg aagagctcct cgaacagctc cgtcatcgcg ggctggcgcg
    14221 cgaagtcccg ggagaactcg gtcagcagat gagccgggat gtgccccgtc tgcgggacac
    14281 cgcccagccc cggatcgccg agcagcaccg tctggtactt gccgatcgac agcccgacca
    14341 gatagctgga cgtcggcgcc ggctgctcgt acacccaggt ggtcgtggac gccttcgtcg
    14401 tacgagtgag caggcgcccg cccgccacca ccgagtacgc cgacggcgtc gtgaccgaga
    14461 gctggtacgc ggccttgtcg gcggggcggt cgttgcacgg gtaccaggac ggcgcgccca
    14521 ccggctggct cgccaccagc gcaccgtcct ccagctcctc ccagccgaga ccgccccagg
    14581 cgctgttgac cggctgggga ttgcccgacc agtgcacctc cacggtgaac gccgcgccgg
    14641 cccggaccgg cttcggcgga cggatgcgca gccggccgcc gcggtgcgtg tagtgcggcg
    14701 ccttgccgtc gacccggacc cggccgatcc ggaagtcggc caggttcagc tggaactcgg
    14761 cgagcggagc ccggcccgct atggcgttga gccgcgcggt gccggcgagc cggttcgggc
    14821 cgggacggta gtccagcgtg agctcgtagc ggtgcacccg gtagcgggca tcaccgttcg
    14881 tggggaagta cggatcggct tccgccttct gccgagggct cactgctgcg tctgctccct
    14941 gcgctgggct cgtacgtcgt gccggtgcac cgtccttcgg cccggagcga gtcacctcgg
    15001 tcacgcccgg ggacgccacg cctcgatcgg gttgcccagc cagcgggtgt cgtcggggac
    15061 ggattccgcc gccatgacga gcgacgcggg tcccagcgtg ctgcgcgccc cgactgtgct
    15121 gccgggaagg acgattccgc ccgggcccag agtggcgccc tcacggagga caacagtatc
    15181 cgtccgcaag atccggtcgt ggaagaggtg ggtctgcagg acacagcccc ggttgaccgt
    15241 ggtcgcgtcc tccagggtca ccaggtccgt ctcgggcagc cagtaactct cgatccacgc
    15301 gcccttgccg atacgggcgc cgaggccgcg cagccacgcc gtcatcagcg gcgtcccggg
    15361 cacggatccc gccagccacg gcaccgcgac gacctcgacg aaggtgtcag ccagctcatt
    15421 gcgccacacg aaaccgctcc acagcgggtg ctcgcccgcc cggtgccggc ccaccagcag
    15481 ccacttcgcc acgacggacg tcaggcaggc gagcacgccg gcgcccagga acacgagtcc
    15541 ggccagcagc ggcgcccagc cgcccagcgc gctcagcgcg gcgacggtca gcaccaccag
    15601 cgccgccgag cagaacaccg gcacgatccg gcacagctcc acgagcgccc gtccccacag
    15661 cagccgcgcg ggcgggtcgt aggtacggct ctgatcgccg tcccgcgtcg aacgcggcag
    15721 cttcaccggc ggcagcccca ggtacgagct gcccttcttc gccttcttcg gggtcgccga
    15781 cagcaccccg accagcccac cgtccggcac gctgcgcccc ggcgcggtca tcccggagtt
    15841 cccgaggaac gcccggcgcc cgatctgcgc gcgcccgatc cgcatccagc cgccgcccag
    15901 ctcgtacgga gcggtcaggg tgtcgtcggc gaggaacgcg ccctcgccga ccgtggtgag
    15961 actcggcagc gcgagcacgg tggacacctc ggcgccccgc ccgatccgca tgccgagcaa
    16021 ccgcagccac accggcgtga tcagcccggc gtacagcggg aacagcgtct cgcgcgagcg
    16081 gtccatcagc tgcgtgaccg tccacgcctg ccagccggtc cggctgtgcg tggggtgcgt
    16141 gccctcgcgc agccccaggc tgagcagacg tacggcgagc agaagcagca gggcgtacgc
    16201 gcacccgaag gcgagcgtcg ccggcaccag ggcgatcgcg gcaccccgca gggcggcgcc
    16261 gagcccggcg tccggcgcca cgaacacccc ggccaccagc agggcggcca gccccgcgag
    16321 caccggcagc gcactcagcg cgaacccggc cgcgccgtac atcgcccgcc agtacgtgcc
    16381 acgccgcggc cgctcctcgg gccacgcgcg cttcgccttg ccgagcttgc ccgccggcgc
    16441 ccccgcccag cgctgaccgg tgggaatctg cccggcgacg gcggaaccgg gcgccacctc
    16501 ggcccgcttg ccgacccgcg cacccggaaa gaggatgctg cgcgtaccga ccacggcatg
    16561 cgcaccgacc ctgaccgggc cgatctcgag gcggtcgccg tccagccagt ggcccgacag
    16621 atccacctcg gactcgacgg ccgcgccccg gcccagcttg agcatcccgg tcaccggcgg
    16681 caacgagtgc agatccacgt ccgcgccgac cttggcgccc agggcccgcg cgtaccgctc
    16741 cagccaggac ccggtcagcg aggtcgcccc gctgaactcg gccagccgct ccgccgtcca
    16801 cagccgcaga tgcacactgc cgccgcgcgg gtaccggccc ggcctgagcc cccgcagcag
    16861 cagccgggcc ccgcccgccg cgatggcgag ccgcccgggt ggactgaaga acagcaccgc
    16921 tccggcggtc accacccacc aggaggcgga cggcgcccac ggatacgggc cgaaccggtg
    16981 cagtacgttc cccagcgcgg ccagtgccac cgtccagcgc agcccgagca gcgtgaacag
    17041 cgggatcagc aggagaagct gaagggcctt ggcacgcggc gggaccgggg cgatcacgcg
    17101 ggccgctccg tcgtcccgcg tggacctctc cagccggcgg gccagcttgc gcagcaccgg
    17161 ctgctggtag acgtcgagga cggccgcgcc cgggtagcgg gtgcgcagcc tggtggtgag
    17221 ctgggctgcg gccaggctgc cgccgccgat cgcgaagaag tcgtcaccgg cgccgccgac
    17281 cgggatgccg agcacttcgg tccactgctc ggcgagccag gcctcggtgc cgtagagctc
    17341 ggcggtgggg gcctccaccc cttccagcgg ccagggcagc gcagtgcggt cgaccttgcc
    17401 ggacgtgcgc gtcggcaggt cggcgacggg cgcgagcagc ggtacgaggg cggccggcag
    17461 ctcggcgcgc agcttctcga cggccgctgc ctggtcccag ccgtcctggg tgacgacata
    17521 gccgacgaga agctggttgc cgctgcgggc ggtgcgcacg gcggcggccg cgcccgcgac
    17581 ccccggcagc gcctggagcg cggcgtccac ctcgcccagc tcgatccgac ggccgccgag
    17641 cttgatctgc tcatcggccc gcccgaggaa gaccagcccc tcgggctcgg ccctgacgag
    17701 gtcaccgctg cggtacgcgc gcgcccagcc gagcgacgcc agcggcgcgt acttctccgc
    17761 gtccttctcg gcgtcgagat agcgcgcgag gcccacgccg ccgatcacca gctgcccgct
    17821 gccgcccatc ggcaccggct ccccggcctc gtcgacgacg gccagctccc agccgcccag
    17881 gggcagcccg atccggatgg gctcgttccc ggtcaggaga gaggcacagg ccacgacggt
    17941 cgcctcggtc gggccatagg tgttccagac ctcgcgcccc tcggtgacca gccgctccgc
    18001 cagctcgggc gggcaggcct caccgccgaa gatcagcagc cgtacgtcgc tcagggcctc
    18061 gggctcccag agggcggcca gtgtgggcac ggtggagacg acggtgatct cctgctcgac
    18121 tagccagggc ccgaggtcgg cgccaccgcg gacctgcgag cgcggcacgg gcaccagaca
    18181 ggccccgtac cgccaggcca gccacatctc ctcgcaggag gcgtcgaagg cgacggacag
    18241 cccggccatg acccggtcac cggggccgat cggctcctcg gtgaggaaga ggtcggcctc
    18301 ggcgtccacg aaggcggcgg cgctgcggtg actgacggcg acccccttgg gcctgccggt
    18361 ggagccggag gtgaagatga tccaggcgtc gtgcccggta ccgggccgcg cggcggggac
    18421 cccggccgtc ccgtcgacgg tcaggtggtg cccggccccg acgaccgccc gcacctctgc
    18481 ctccccgaag accagttcgg cgcgctcgtc ggggtcctcg gcgtccaccg gtacgtaggc
    18541 ggcgccggcg gccagaacgg ccaggaccgc gatgtacaga tcgttggtcc cggacgggac
    18601 acggacgccg acccggtcgc cgaggccgac tccggcggcc gcgagccgcc gccgcagggc
    18661 ctcgatctcg acggcgagcg cacggtaggt gaggcagcgc cggccgtcgt cgagggcggg
    18721 ctcgtcgggg tacgcccgga cggaggcgtc gagaatgtcc acaagggtcc gaggcgaggc
    18781 gggggagccg gcggagaagc gtgcccggtc accgaactcc gcccgcacct cgtcgtcgga
    18841 cagcgcgagt gcggggcctt gctggagggc agccatcgag tcctcacgtg tcgttcccgg
    18901 agcgatcggg agcgctggtg ggcccgcagg gatgcctggg gatgttccgg tccagcgccg
    18961 aacaagctgg aaactgtagt ccgacgctag ccgccgacca gcacgtcagc catgcgagga
    19021 ggccctcgac ggactgcgga ggctctgatt ccggagtcct gccatggtca cgggcgcgta
    19081 ctccgcaaaa aacggtgccg actcgatcag agtcagcacc gttctgggat cctgctgtgg
    19141 tgtccgaggg gggacttgaa cccccacgcc cgataaaggg cactagcacc tcaagctagc
    19201 gcgtctgcca ttccgccacc cggacaaggt gtctgtcgcg cggggtttcc ctcgcggcga
    19261 cagaggaaac attaccaggc tttcgagagc ccctgatcac cccccgtccc cgcgtgaacg
    19321 gcgtgtgacg ggccgggtcc cgccttgggc ggcgcgggcc ggcggaggga ggatgagggg
    19381 gaccaccagc agcgacagtg ggaggaagca gcgtgagcga gtcgaacacg gccaggggca
    19441 tctctggcga ggacgaggtc gtggacctct gtcgcgagct gatccggatc gacaccagca
    19501 actacgggga ccactcgggg ccgggcgagc ggaaggccgc cgagtacgtc gccgagaagc
    19561 tcgccgaggt cgggctcgaa ccgcagatct tcgagtccca ccagggacgc gcctccacgg
    19621 tcgcccgcat cgagggcgag gacccgtccc ggcccgcgct gctcatccac ggccacaccg
    19681 acgtcgtacc ggccaatgcg gcggactgga cccaccaccc cttctccggc gagatcgcgg
    19741 acggctgtgt ctggggccgc ggtgccgtcg acatgaagga catggacgcg atgaccctgg
    19801 cggtcgtacg cgaccggctg cgcaccgggc gcaggccccc gcgcgacatc gtgctcgcct
    19861 tcctcgccga cgaggaggcg ggcgggacgt acggcgccaa gtacctcgtc cagaagcacc
    19921 ccgacctctt cgagggcgtg accgaggcga tcggtgaggt cggcgggttc tccttcaccg
    19981 tcaacgagaa gctgcggctc tacctcgtcg agacggccca gaagggcatg cactggatgc
    20041 gcctcaccgt cgacggcacg gcaggccacg gctcgatgac caacgacgac aacgcgatca
    20101 ccgagctgtg cgaggccgtc gggcggctcg gccggcacac ctggccggtg cgggtcacca
    20161 agaccgtgcg gtccttcctc gacgagctct ccgacgcgct cggcaccgag ctcgacccgg
    20221 agaacatgga cgagaccctc gccaagctcg gcggcatcgc caagatggtg ggcgccacgc
    20281 tgcgcaactc cgcggcgccc accatgctgg gcgccggcta caaggtcaac gtcatccccg
    20341 gccaggccac cgcgcacgtc gacgggcggt tcctgcccgg tcacgaggag gagttcctcg
    20401 ccgacctcga ccggattctc ggcccccgcg tgaagcgcga ggacgtgcac ggggacaagg
    20461 cgctggagac cgacttcgac ggcaggctcg tcgacgcgat gcagagcgcc ctgagcgccg
    20521 aggacccgat cgccaaggcc gtgccctaca tgctctccgg cggcaccgac gccaagtctt
    20581 tcgacgacct cggcatccgc tgcttcggct tcgcccccct gaaactgccg ccggagctgg
    20641 atttcgcggg catgttccac gggatcgacg agcgtgtgcc ggtcgacggg ctcaagttcg
    20701 gcgttcgcgt actcgaccgg ttcatcgacg cgtcctgacc attgagcgag gcgccctctg
    20761 aaacgattac tcaataatcg gccgcccgtg cggagttgac tgagaagagt gaatgcgacc
    20821 ataagctcgt agctccatta ctccctcctc gttacaggta gtgcgatcag ctacttggga
    20881 tcgcattgcc aacaaggagg aataatgatc aagaaggtcg tcgccgctgc ggctgccact
    20941 ggtggcctgg ttctcgcggg tgcgggcctg gccgtcgccg actcgggtgc ccagggtgcc
    21001 gcggtgcact ccccgggtgt cgtttccggc aacgtcatcc aggtgccggt tcacgtcccg
    21061 gtgaacgtct gcggcaacac ggtctccgtg atcgggctgc tgaaccccgc cttcggcaac
    21121 acctgcatca acaagtgacg ttgtgagccc gtcggccccg gagcgcgcgc catgcgctcc
    21181 ggggccgacc ggtcttttcg gttcgagaca aggtcgaagg cagggattca gcaatgcgac
    21241 aggtcacccg caagggcctg atgaccgtgg cggcggcgac cggcgtgctc gccgccaccg
    21301 gcggctacgc acacgccgac tcgggtgcgt acggctccgc gtcacattcg cccggcgtgc
    21361 tgtcgggcaa ctcggtccag gtgccggtgc acgtgccggt gaacgtctgc ggtaacaccg
    21421 tgaacgtggt cgggctgttc aatccggcgg tgggcaacca atgcgccaat gggggcggcg
    21481 gcggtcacca cgatggcggc ggtcaccacg gaggcggcgg tcaccacggt ggcggctacg
    21541 gcgacagtcc gtccggtggt ggcggtcatc acggtggcgg cggtcaccag ggcggcggct
    21601 acggcgacgg cccgtccggc ggcggtggcg gcggtggtgg gtcgcaggcc ggcgggcaca
    21661 ccggcgactc gccgggcgtg ggctccggca accacgtcca ggtcccggtg gacgtgccgg
    21721 tgaacgtctg cgggaacaac gtcaccgtgg gcgggctcgg caacgcggca ggcggcgacg
    21781 cctgcgccga caccccgggc ggcggccacg cgacgacccc gcccggcggc ggtggcggga
    21841 cgacacctcc gggcggcggc ggcggtggca cgacgcctcc gggcggtggc ggtggcggga
    21901 ccacgcctcc gggcggtggc ggtgggacga cgcctccggg cacacccgga caccccgggc
    21961 agccgggcgg cgacagctcg gcgcacccca accaccccgg tggacagtcc gtcacccagc
    22021 ccgagggcac cgcgcagctt gcccacaccg gcagcgacat gccgctcggc ctgctggtac
    22081 cggcgggcgc gggcgcactg ctcggcggcg cgctgctcta ccgcagggcg cgatcggcag
    22141 cgtaaaaaaa cagcaaaggc caccgtatgg ggccgtggac ttccccggtg atgtggagaa
    22201 cggagcgggc cccgtgagtg cggggcccgc tccgtttcgg ccgccttttc tcaccatgtg
    22261 gcgcgcacct ggcggatgat ccgtcggcgc aaccgcaccc tgcggctgcc gtcgcggtgc
    22321 aggctgaggc ggtccaactc ccagtggccg tactcggcat ggtcggtcag caggcgtgtg
    22381 gcttccttgc gggacacccc gcgaggcacg tacacgtcga caaattcgta ttccggcatc
    22441 gcatctattg tgcgggcaga ggccgtgtac ggatagcgtc tgcactatgt ctgatgctgc
    22501 gcagtccacc gctgccgagg tacgtgccgc cgcggaggcg gtcaagaccg cgctcgaccg
    22561 ccacctggcc gcggtcgagc gcaggtcggg cgaggacgac ccggccgtct atgaggcgtt
    22621 caacgagctg gccgcggcgg ccgaggagta cgacgaactg ctctacgacc gctatgacga
    22681 ggtcacgccg ttcgagatcc ccggcacgga cgattcgctg cccccgtaca cgggacccga
    22741 ggagcccagc gcggtgagtg tgctgatccg ccgggactac gcggtggtgg agccgcaacg
    22801 actgctggcg caggctcagc gggtcgaggc cgcggaggag cccgccgacg aggtggccgg
    22861 cacggtccac ggggcgctcg gtgtgctgtt cgaggagtac gagccggacg agatcgcctc
    22921 ccggcacaag gagttcggcc tggaggaggg cgactccaca ctctgggtga cggccgagga
    22981 ggagcggccg gagccggggg agtggctgga ggcccccttc gagcagatcg acccgcagca
    23041 catcgtgtgc cgcttcgatg ccagcgccgt ctacgacgag gagtcggacg gcgaggagtc
    23101 ggacggcgag gttccggagg acgacctcgg cccggactcc gagctcgacg gggagctgga
    23161 cgaagacgac ctggaaccgc tggacgcgga tcgctgagca tctgccgagg gcggcggtca
    23221 ccggaatccc ggtgaccgcc gccctcgcgt tggccccccg ccctcgttcg ttcgcccgcc
    23281 ctcgcgttcg cctgccgtgg tccgttcgcc cgccggccgc gcggccggct cagtcggcgg
    23341 ccggaacctg gggcctgagc agggcgggca ggcgcgtggt gcgcggcttg gcggtgacct
    23401 cggccacggc ccggggcagt gcctgctcca ctccgtgcac gacggacaga tggcgctcgg
    23461 ccaggccgaa cgccgtgtac acccaggggc gggtcaggga ctgcgccgcg tcgccgggca
    23521 ggaccacgac cgcggcgggc caccggctcc ccaccgcctg gtgcgcggtc agcgcccagc
    23581 cgtgccgcac gcactgctcc acccgctcct tcggtacgac gacgggggcg cccgggatct
    23641 ccaggtgcag cccgtcggcg tcggccttca cgacgcggcc cggcagcgta cggcccgggg
    23701 cgggggagta cgcgatccgg tcaccgggat cgaatccgcc gaagcgcccg gggcccgggt
    23761 tgagccgctc cttgagcgcg gcgttcaacg cgcgcgtgcc ggccgcgcca ccgtgccccg
    23821 gagtgatcac ctgcgtctgc tcggccggga cgccgagcgc ccgcggcacc gagtccgcga
    23881 ccagctgcac ggtgcggtgc accgcttcac cggcgtcccg caccggcacg atcacgacct
    23941 ccttgccggg cgcctcgacc tggttcagct cgccgacgcc gatgccggag atcagctcgc
    24001 cgatcggtcc gggatcgggg gtgcgcgagg cgatccccgg gcagacgcgt gcggcgagca
    24061 gatccgcgaa cacccgtccc ggaccggccg accacaacac ccccgggtcg ccgctcagca
    24121 ccagccgggc cccgtcgggc agcgactcgg cgagcatggc ggcggtctcg acgtcgagct
    24181 ggggagcgtc caggacgacc aggaggtcga ggaccagggc gccgtccgcg tcccggccgg
    24241 gaccctccgc gccggacagc agacccgcca cggtggagac accggtgccc gggccctgct
    24301 gcggcccgcc cggcaggtcc gacggggcga gccgagccgt gaagcggtcg cagccgatcc
    24361 ggctgtgcgc ggcggcccag gtccgcagcc ccagcccgcg ggcggcggac agcagcgccg
    24421 cggcctccgc accggaggcg tcgccgccgg tgtggaggac caggccgtgg cccgcgaccg
    24481 cgcggatcag ctccgcggcg gagccgcccg ccgatgcggc ggcccgctcc cagtcggcgg
    24541 ccgagccgtc ctccttcggc acggagttca tcacccggcc gagcgcgtcg gcgaggctct
    24601 cctccgcgag ggcgtaccgc tccaggccga tcaggacgcg gaccggacgc tccgctccct
    24661 cctcctcggc ctccgcctcc gcggcgggcg cggccgcgtc gagggcgtcc tggaacacca
    24721 gcacctcgcc ctcggcgagc gcgctctgca ccgctgtgtc cgggtccggc acggcccgct
    24781 gcgcgagcgc cgtggtgagg gccgccacct ccagcgccgt atgccccgcg agggccgcct
    24841 gctccagcag ccacaccgtg accgcccggc cccgccgctc gtcgtccggg ccgcactccg
    24901 cgccgagcag cgcccgggcg aagccgtcgg cctgctcggg acgcactccg gagacccgca
    24961 gcaactgcca ggggtcctcg cgcagttgca ggtcggctcc gtcgcccagg agggcggcga
    25021 gctgcggcgc gagcgcctcg ggggcgccgc cctcggtcag tacggcacgc acaccggcaa
    25081 cggcttgtgc cgcggggacc gccggcccgg ccggggccgc cacgggctcc gggcgccgct
    25141 cgggctcggg ggccggcctg cgcggcgccg gcggctcgct gaaagcgctg gccaccggct
    25201 tcgcaccgct ctccacgacc cgcaccgccg cgagcagatc ggcggccgtg ccgctcagct
    25261 tcgtgccggc ctcgatcggc gcctgcttct ccgccttccg ccgctcgatc cgctcccgct
    25321 cgacccgctg ggccgccaac tcggcctcgg cctcggtggg cttggccgcg tcgcccgagc
    25381 cctcggcagt gcccgccgcc tcactcccgg ctgtgccttc ggagctctcg gtagcgcccg
    25441 ccgcctcact cccggctgtg ccttccgcgg agctctcggc gtcgcccgcc gccccgctgc
    25501 cgggcgtgcc ctcggtctcc gggacgccgt ccaccgcacc ggcgccgggc tgtcccggtt
    25561 cgacttcgcc cgcacccgcg cccggctgcc ccggctcggc ttcgtccgtg gtctccggct
    25621 ccgtggtcac agcgtgctcc agtcctggtc gggatagtgg tgcaccgggg ccgacacgtc
    25681 gtccagcgcc cggcagatct cgtcaggaag actaagggtc tccactgaca acgccgccgt
    25741 gagctgctgc gcgttgcgcg cgccgacgat cggcgcggcc acgccgggcc ggtcgcggac
    25801 ccacgcgagc gccacctgga gcggggtgac cgcgagaccg tcggccgcgg tctgtaccgc
    25861 gtccacgatg ccgctcgccg tgtcgtcgag atagggagcg acgaacggag ccagatgctc
    25921 cgaggcgccc cgggagccgg cgggcgtccc gccccggtac ttgcccgtca agacgccccg
    25981 gccgagcgga gaggacggca gcagcccgac ccccaggtcc agggcggccg gcagcacctc
    26041 ccgctccacg ccgcgctgga gcagggagta ctccatctgt gtactggcga tccgggtccg
    26101 cgggcccggc gccgagagct gccaggtggc cgccttggcg agctgccagc cgcagaagtt
    26161 ggacacgccc gcataccgcg cccgtccggt gctgaccgcg aggtcgagcg cctggagggt
    26221 ctcctccagc ggggtgtgcg ggtcgaaggc gtggacctgc cacagatcga cgtagtccgt
    26281 gccgagccgg gcgagcgagg cgtccagcgc ggagagcaga tgcccgcgcg aaccgtcgaa
    26341 ccgccggtcc gggtccgcta cgctccccgc cttcgtcgag atgaccaggt cccggcgcgg
    26401 cacgagccct tctatgagct gtccgagtac gtactcggct tctccgtcgc cgtacacgtc
    26461 cgcggtgtcg acgagggtcc cgcccgcctc ccagaacacc ttcaacagct ccgcggcgtc
    26521 atgctcgtcc gtgtcgcgcc cccacgtcag ggtgccgagc ccgatccggg acacacgcag
    26581 gccggtacgg ccgagatgcc tctgctccat ggacgccgag attactggcc agaactcgat
    26641 acgtggtggc cctgtggaca accgggatca ccccagctcg aaccccgtcc ctgcccctgc
    26701 gtccgccggc gcgctagtgt ctccggaaca agggacgtta ctgatcggta aggggaatcg
    26761 gccatgcagc tcgggatcaa cctcggctac tggggcgccg gaatggacgc ggacaatctc
    26821 gccgtcgccc aagaggccga ccggctcgga tacggcgtct gctgggccgc cgaggcctac
    26881 ggctcggacg ccgccaccgt actcacctgg gtcgccgccc agaccgaacg catcgacgtc
    26941 ggctcggcca tcttccagat cccggcccgc cagcccgcga tgaccgcgat gaccgccgcc
    27001 accctcgact cgctttccgg cggccgcttc cgcctcggcc tcggcgtctc cggcccgcag
    27061 gtctccgagg gctggtacgg cgtcaagttc gacaagccgc tggcccgcac ccgtgagtac
    27121 gtcgagatcg tccgcaaggc gatgacccgc gagcgcctgt cgtaccaggg cgagcactgg
    27181 accctgcccc tgcccgacgg cccgggcaag ccgatcaagc tgaccgtcca ccccgagcgt
    27241 gagtacatcc cggtctacat cgccgcgatc ggcccgaaga acctggagca gaccggcgag
    27301 atcgccgacg gtgcgctgct catcttcccc tcggccgacc acctcgagga caccgcgatc
    27361 aagcacctgc gggcaggccg ggagaaggcc ggcaagacca tggacggctt cgacgtctgc
    27421 ccgaccctcc cgctcgcgct cggcgacgac aagaacgtga ccgcgctcgc cgacacgttc
    27481 cgcccctaca ccgcgctgta cgtcggcggc atgggcagcc gcaagcagaa cttctacaac
    27541 cagctcgccc agcgcatggg gtacgagaag gaggccgccg agatccagga caagtacctg
    27601 tccggcgaca aggagggcgc cgcggccgcc atcccgcacg agctgatcga ccagaccacg
    27661 ctgctcggtt ccgtggaccg catcgcggac cggatgaagg cctacgcggc cgccggggtc
    27721 accacgctca ccctggcgcc cgcgggcttc acgctggagg agcggatcgc cgcgctgcgg
    27781 gcggggaccg acgccctgga gcgggcgggc ctcgcataac gcggcggacc acgccgagaa
    27841 gtttccgcgg ccgtggtggg ggctcggggg tcttccccgc cacggccgtc ttcgggcaca
    27901 acgcctcgga cgccttccgg gttacgcgtc gaggtgttcc acgccgtccg tcgttcggcg
    27961 gagcggtccg acacatctgt tgccgtactt ctgacatccc atttgactcg gtttctgcgg
    28021 aaactttgca tggaggtggc agtgatgctt tcggtcagga gtctgttcca ggagatcctc
    28081 gacaacgacg agtcgttccg gctcttctgc tccatcgctg ccagcggcga gtcccagggc
    28141 ggctgggaga acgggcggat cgccgcgctc gtcccgcaca gccagcgtga cctcgccccc
    28201 aagatcaccc ggcacggcgc cgacgaggac aaacacgggc ggatcttcca cgccctcatg
    28261 aagaagcgcg gcctggaccc cgtagcgatc ccgcccgaca ccgactacac gatgctcctg
    28321 gaacggcacg gcatcggtct cgcccacgag aagctcaagg gcgacgagcc gctcaccgtg
    28381 caggacatcg tcacctacct cgcgcacagc agggtcaccg agcagcgcgc cgccgagcag
    28441 atggagctgc tccgcaggca cttcgccgac catcccgaca tcggccgcgc ggtcaggatg
    28501 atctcccacg acgaggacaa ccacctcgcg tactgccacg aagagctgtt gcgcttcgcg
    28561 tacaccggac acggccgcgc catccagcgg acgctgcggc agtgcgcgct cgccgagatc
    28621 cgcgtctacc gggacgtcag cctcgccgtg atggcccaca tgggccgcct cctcggctgg
    28681 ccgaaggcca gggcggcggc gctcgcggcc ggtatccacg cggtgtacgc ctacgagcgc
    28741 gccgtcggct ggcgccgcat ggtctccctg aggatgccgg agcgccgcga cgcgctgggc
    28801 ggaccggcga ccaccgccgc cgagtacgcg taggggcggg tccttcggat ctcccagggt
    28861 ccgcgacgcc gcggtgacat cagccgctcc acggcgggcg gcacctcgcc gtgtggtcgc
    28921 acgccgttgt cgcacgaccc gcgcacgccc cgtgggtcgt gccccgccct gtgacgcacg
    28981 cgccccggac caccgcgtac gcccgcgtcg ccgcccgcgc ctacagccac ccccgctgct
    29041 tgaacagccg gtacagcaga acctcgagca ccaccatcgc cgcgatcacc gccggatacg
    29101 accacgtcca gtgcagctcc ggcatgtgct cgaagttcat gccgtagatc cccgcgatca
    29161 tcgtggggat cgccgccatg gccgcccacg cggagatctt ccgcatgtcg tcgttctgac
    29221 gcacgctcat ctgcgcgaga tgcgccgaga ggatgtcgga gaccagccgg tccaggccct
    29281 ccacggattc gttgacgcgc gtcaggtggt cgttgacgtc gcggaagaag ggccgcgcct
    29341 cctccttcac gaacggcacc gccgcgaggt tgggccccag gccggcgagc cgggtcagcg
    29401 gcggcgtgag cggaaccgtg gcccggcgga actcctggat ctggcgcttg aacgagtaga
    29461 tccgcgacgc cgtgttccgc gccccgccgc tgggcgagaa gacctccgcc tccagctcct
    29521 ccagatcggt ccccagctcc gtggccacgt ccagatagtg gtcgacgacg gagtccgcga
    29581 tcgcgtgcag caccccggtg ggaccgtgcc ggagcatgtc cggccggcgc tccagttcgt
    29641 gccggatgct cgacagcggc gcaccctccc cgtggcgcac ggtcaccacg aaggagtcac
    29701 cgacgaagac catgacctcg cccgaggaga cggtgtcgct gtacggctcg tacgtcaccg
    29761 gcttgaggac cacgaacagc gagtcgtcgt acacctccag cttgggccgc tggtgcgcct
    29821 tcagggcgtc ctcgacggcc agcggatgga gtccgaactc atgggtgacc aggtcgaact
    29881 ccttctccgt cggctcgtgg aggccgatcc agaggaagct gtcaccctgt gcacgcgcct
    29941 cgtcaagggc gtcggagagg tcctccgggc cctccgtgcg gcggccgtca cggtagatgg
    30001 cgcaatcgac gatcactgag cgtattcttc cgtcgcgcgg acaggtgcgc actccggacg
    30061 tcgccgggag ccggcccggt gaggaccgcc gggggcccct ttaggctggg ccgcatgccc
    30121 acgttgatcc tcgtccggca cggacgttcc accgcgaaca ccgcgggact gctcgccggg
    30181 tggacgcccg gcgtcgccct cgacgagcgg ggcgccgccc aggccgccgc cctcccgggc
    30241 cgcctcgccg aggtgccggt ctccgagatc gtcaccagcc cgctccagcg ctgccgggaa
    30301 acggttcagc cgctgctcga cgcccgcccc gggctgcgcg cgcacaccga ggaacgcatc
    30361 ggggagtgcc actacggcga ctggtcgggc cgcaagctcg ccgagctgaa ggacgagccg
    30421 ctgatggagg tcgtccagtc gcacccgtcg gcggccgcgt tccccggcgg cgaatccatg
    30481 cgcgccatgc agacccgcgc cgccgaggcg gtgcgggagt ggaacgcgcg cgtggagcgc
    30541 gatcacggct ccgatgccgt ctacctcatg tgctcgcacg gcgacatcat caagtcgctt
    30601 gtcgcggacg cccttggact ccatctggac ctctttcaac gaatctccgt agaaccgtgt
    30661 tccatcaccg cgatccgtta cacccgactg cggccttttc tcgttcgcct cggggacacc
    30721 ggcgatttcg cgtcccttgc cccgcgcgag gaaccctccg gtggcgacgc tccggtcggg
    30781 ggcggtgcgg gcgcaccgtg atcgtcgacc gcagtagggt gaagcggtcg aaacagagca
    30841 gacgttgtca gcagccgatg gggaccgacg cggtcggtcg tcccacatgc cgaatccaat
    30901 ggagacagga cgtgtcgcgt caggtgttcc tctacgaccc cccggaccgt ttcgtggccg
    30961 gtacggtcgg gctgcccggg cgccgtacct tcttcctcca ggcctcctcg ggaccccgtg
    31021 tgaccagcgt ggccctggag aagacccagg tcgccgcgct cgccgagcgc atggacgagc
    31081 ttctcgacga ggtcgtacgg cgcagcgggg gcagcgcccc ggtccccgcc atggccccca
    31141 ccgagatctc cgacaacgcc cccctcgagg ctcccgtgga ggaggagttc cgggtcggca
    31201 ccatggcgct ggcctgggac ggtgacgagc agcgcatgat cgtcgaggcg caggccctcg
    31261 tggagctcga cgccgaatcc gacgaggacc tcgccgaggc ggaggagcgg cttctccagg
    31321 acgaggagaa cggtccgccg atgctccgcg tccggctcac cggcctacag gccagggcct
    31381 tcgccaaacg ggccctcgac gtcgtcaacg ccggccggcc gccctgcccg ctgtgcagcc
    31441 tcccgctcga cccggaagga cacgtatgtc cgcgccagaa cggataccgc cgcggagcgt
    31501 gaccacggcc gaactgctcg ccgagggtga gctgaaagta cgtggccgca tccgcgaggc
    31561 gtccaacgcg gcgctgtact gcacggtctc gcacgacggg caggaggcgt tctgcatcta
    31621 caagcccgtc gccggcgagc ggcccctgtg ggacttcccc gacgggacgc tcgcccagcg
    31681 cgaggtcgcc gcgtacgagg tctccgaggc gaccggctgg gggctcgtgc cgaccaccgt
    31741 gctgcgcgac gggccctacg gcgagggcat gtgccagctg tggatcgagg gacagccgga
    31801 cgtcgagctg ctggccctgg tggacggcga ggagcccgag gccggctgga aggcgatcgg
    31861 gttcgcggac gtcggggagg ggcgtacggc gcttctcgtg cacgccgacg acgaacgcct
    31921 gcggcggctg gccgtcctcg acgccgtcat caacaacgcc gaccgcaagg gcggccatct
    31981 gctgcccacc gacgagggcc gcctgtacgg catcgaccac ggggtgactt tcaacaccga
    32041 gaacaagttg cggacgctgc tgtgggggtg ggcgggggag ccgctcacgg ccgacgctgc
    32101 cgaggccctc ggcaccttga aggacggcct gacggcggga ggcgccctcg ccacccgtct
    32161 ggcggagctg atcacaccgg ccgaactcga cgccacgcgc gcgcgggtcg acgccatgct
    32221 cacctcggga aagcacccgg agccgagcgg tgagtggccg gcgattccat ggccgccggt
    32281 ctagggcccg atgtcgtggt cgtgagcacg atttcggggc cgccggtgtc gcggagcgcc
    32341 gaacgcatgc cgggcggcat tgcgcaagag ggccttctcg gtcatcaggc ctggtccggt
    32401 tcgtatacgg aacatccgtc cggttaggct catgacatgc atgcctggcc cgcttctgag
    32461 gtccccgccc tgcctggtga gggccgcgac ctccggatcc acgacaccgc gaccggcggg
    32521 gtaatacccc tgcaccccgg tcccgtcgcc cgtatctacg tctgcggcat cacgccgtac
    32581 gacgcgaccc acatgggtca cgcggcgacc tacaacgcgt tcgaccttgt gcagcgcgtg
    32641 tggctcgaca ccaagcggca ggttcactac gtccagaacg tgaccgacgt cgacgatccg
    32701 ctcctggagc gcgcggagcg cgacggcgtc gactgggtcg ggctcgccga gaaggagacc
    32761 gccctcttcc gcgaggacat gacggcgctg cggatgctgc ccccgcagca ctacatcggc
    32821 gccgtcgagg cgatacccgg catcgtcccg ctcgtcgagc ggctgcggga cgcgggcgcc
    32881 gcgtacgaac tggacgggga cgtctacttc tccgtcgagg ccgacccgca cttcggcaag
    32941 gtctcgaacc tcgacgccgc cgccatgcgt ctgctctccg ccgaacgcgg cggcgacccg
    33001 gaccgtcctg gcaagaagaa ccccctcgac ccgatgctct ggatggccgc ccgggagggc
    33061 gagccgagct gggacggcgc ctcactgggc cgcggcaggc ccggctggca catcgagtgc
    33121 gtggccatcg ccctggacca cctcggcatg ggcttcgacg tacagggcgg tggctccgac
    33181 ctcgccttcc cgcaccacga gatgggcgcc tcgcacgccc aggcgctgac cggcgagttc
    33241 cccatggcca aggcgtacgt ccacgccggc atggtcgcgc tcaacggcga gaagatgtcg
    33301 aagtccaagg gcaacctggt cttcgtgtcg aagctgcggc gtgacggcgt ggacccggcg
    33361 gccatccgcc tggcgctgct cgcccaccac taccggtccg actgggagtg gacggacgcc
    33421 gtcctcgaag aggccctcgc gcgcctcggc acctggcgcg cggccgtctc ccgccccgac
    33481 ggtccgcccg ccgaggcgct cgtcgaggag atccgcgacg ccctcgcgaa cgacctggac
    33541 gcgccggccg cgctcgccgc ggtcgaccgc tgggccgcgc tccagcacga gcggggcggt
    33601 accgacgagg gcgcgcccgg cgtggtgtcg cgggccgtcg acgcgctgct gggcgtggcg
    33661 ctgtaaccgg ccgggtacgc ggccgggcgc cgggcgggtt ctcacccgcc cggcgccctc
    33721 cgcgccggga gcatgcgctc ctacgtcatc caggtgccgc cacccgggct acttcgtcac
    33781 gatgacggac tgcaggacgc cggtcgcggt gtcgtagatc ccgtagaccg gctgcccgta
    33841 ggcgaaggcc tcctggaccg cgtcgtgcgt cacctg
//
