LOCUS       NC_003155              41086 bp    DNA     linear   CON 12-JUL-2024
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893, complete sequence.
ACCESSION   NC_003155
VERSION     NC_003155.5
KEYWORDS    RefSeq.
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Ikeda,H., Kazuo,S.Y. and Omura,S.
  TITLE     Genome mining of the Streptomyces avermitilis genome and development
            of genome-minimized hosts for heterologous expression of
            biosynthetic gene clusters
  JOURNAL   J Ind Microbiol Biotechnol 41 (2), 233-250 (2014)
   PUBMED   23990133
REFERENCE   2
  AUTHORS   Ikeda,H., Ishikawa,J., Hanamoto,A., Shinose,M., Kikuchi,H.,
            Shiba,T., Sakaki,Y., Hattori,M. and Omura,S.
  TITLE     Complete genome sequence and comparative analysis of the industrial
            microorganism Streptomyces avermitilis
  JOURNAL   Nat Biotechnol 21 (5), 526-531 (2003)
   PUBMED   12692562
REFERENCE   3
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kikuchi,H., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Genome sequence of an industrial microorganism Streptomyces
            avermitilis: deducing the ability of producing secondary metabolites
  JOURNAL   Proc Natl Acad Sci U S A 98 (21), 12215-12220 (2001)
   PUBMED   11572948
REFERENCE   4  (bases 1 to 9025608)
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kushida,N., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2002) Contact:S Omura Kitasato University,
            Kitasato Institute for Life Sciences; 1-15-1 Kitasato, Sagamihara,
            Kanagawa 228-8555, Japan URL
            :http://avermitilis.ls.kitasato-u.ac.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000009765.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:55:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,040
            CDSs (total)                      :: 7,942
            Genes (coding)                    :: 7,651
            CDSs (with protein)               :: 7,651
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 293
            CDSs (without protein)            :: 291
            Pseudo Genes (ambiguous residues) :: 0 of 293
            Pseudo Genes (frameshifted)       :: 128 of 293
            Pseudo Genes (incomplete)         :: 220 of 293
            Pseudo Genes (internal stop)      :: 25 of 293
            Pseudo Genes (multiple problems)  :: 77 of 293
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:08:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4335458
            Orig. end                         :: 4376544
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BA000030.4.
            On Mar 29, 2016 this sequence version replaced NC_003155.4.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41086
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="PKS-like"
                     /product="butyrolactone"
                     /region_number="25"
                     /rules="(t2pks2 or ksIII)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..41086
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..41086
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21086](-)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     gene            337..858
                     /db_xref="GeneID:41540564"
                     /locus_tag="SAVERM_RS18085"
                     /old_locus_tag="SAV_3500"
                     /old_locus_tag="SAVERM_3500"
     CDS             337..858
                     /codon_start=1
                     /db_xref="GeneID:41540564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005485737.1"
                     /locus_tag="SAVERM_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3500"
                     /old_locus_tag="SAVERM_3500"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_010984931.1"
                     /transl_table=11
                     /translation="MAAEAEVLDELHRLRSRVPQLTGALAASVDGLVLAQDTPGVDPDS
                     LAALTAAALGVALRVTDATGQGDFRELLVRGVHGYVATYAAGGTAVLTLLAQDRVNVGR
                     LHLEGRRAGTRIGELIEAAAARAEPAPQTPAAKAPAKAVAKSATPRTRTARAPAKPRTT
                     TNARTTTTES"
     gene            873..1247
                     /db_xref="GeneID:41540565"
                     /locus_tag="SAVERM_RS18090"
                     /old_locus_tag="SAV_3501"
                     /old_locus_tag="SAVERM_3501"
     CDS             873..1247
                     /codon_start=1
                     /db_xref="GeneID:41540565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008417686.1"
                     /locus_tag="SAVERM_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3501"
                     /old_locus_tag="SAVERM_3501"
                     /product="hypothetical protein"
                     /protein_id="WP_010984932.1"
                     /transl_table=11
                     /translation="MTNTETALKEALASIEGATGAALVDYTTGMALGTIGGSKSFDLTV
                     AAAGNTDVVRAKLRTMEHLGLKGEIEDILITLTDQYHLIRLITGRGGNGLFLYLVLDAK
                     RANLAMARHQLKRIEADLEV"
     gene            complement(1255..1839)
                     /db_xref="GeneID:41540566"
                     /locus_tag="SAVERM_RS18095"
                     /old_locus_tag="SAV_3502"
                     /old_locus_tag="SAVERM_3502"
     CDS             complement(1255..1839)
                     /codon_start=1
                     /db_xref="GeneID:41540566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028752.1"
                     /locus_tag="SAVERM_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3502"
                     /old_locus_tag="SAVERM_3502"
                     /product="hypothetical protein"
                     /protein_id="WP_010984933.1"
                     /transl_table=11
                     /translation="MARGGQGLARVAVVVRAGAAPLWWCGAFAAGVGVLVPGLTGRRIG
                     VMAGAVLFLVAAAVVTYGSRKRYTALAAAAARAGKHDVLQDRAVTVRNWRRGHRWWLLL
                     AFVAALVSSFAVPAAGGMLLAGLGTGLRLKAAWLGRRERAGDALLWVRVDWLGAHGGRP
                     AGKAVKVYRSTGIAAGDAAPGGARRRTDALV"
     misc_feature    complement(1887..1905)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.61"
                     /tool="antismash"
     gene            complement(2025..2885)
                     /db_xref="GeneID:41540567"
                     /locus_tag="SAVERM_RS18100"
                     /old_locus_tag="SAV_3503"
                     /old_locus_tag="SAVERM_3503"
     CDS             complement(2025..2885)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000660.1"
                     /locus_tag="SAVERM_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3503"
                     /old_locus_tag="SAVERM_3503"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_010984934.1"
                     /transl_table=11
                     /translation="MSGDRDTEMTDSPAGRLQALFEGHRLTPTQRRIAHSMVRRAADVP
                     FLSSVELAELAGVSQPSVTRFAVALGFDGYPALRKHLREVAPAEQAPDTSSYNEYQQAV
                     EAEIENLKHLAELLADPRPLARAGRLLAASRPLPVLGLRAAASQAYGFAYFAAKVHPDV
                     RLLHEGGTMVQDRIDAAVRAGASALLCFALPRHPREVVDTLAYAREAGLTVVTVADSAF
                     APVAKVSDLLLPAAVGTGLAFDTACAPMLLGRVLLEAMCDDLPDAQARLEEFDARAAAK
                     GLFVE"
     gene            complement(2882..4519)
                     /db_xref="GeneID:41540568"
                     /locus_tag="SAVERM_RS18105"
                     /old_locus_tag="SAV_3504"
                     /old_locus_tag="SAVERM_3504"
     CDS             complement(2882..4519)
                     /codon_start=1
                     /db_xref="GeneID:41540568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019064010.1"
                     /locus_tag="SAVERM_RS18105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3504"
                     /old_locus_tag="SAVERM_3504"
                     /product="aromatic amino acid ammonia-lyase"
                     /protein_id="WP_107083274.1"
                     /transl_table=11
                     /translation="MSSRIVDTSTVEVSPASTGIVVLDGCGIGVSDVVCLADGASRPVP
                     GTEAMKRVEESWDAARQIAATGRVYGRSTGVGANRNEDVPTEAAAGHGLRLLRSHAGAI
                     GAELPARQVRAMLAVRVNQLLAGGAGLRPTVVTALCEALENGAYPVVNEFGSVGTGDIA
                     ALAQVGLALAGEHPWRRAETSGGLGSETSGGPGAGASGGRYAGGVRALRRGASAREIGA
                     PEPQLLDNNDALALISSNALTLGQSALALHELRGLIGATQVVAALSLLAVDGSHEAYAA
                     PVHTARPHRGSAEVARIMRELIGAADRPTPPLGRIQDPYGFRCLPQIHGPAHEAADALE
                     AVLAVEINAAAENPLISPGDLAAYHHGGFYQAQLALALDHFRLAITQVARLSTSRLSTL
                     NEPAYTRLRPFLADHEPASSGVMILEYAAGAALGDLRAFSAPASLGHAVLSRGVEEQAS
                     FASLAARQTLRACDAYRLVVGCELVAAVRALRQRDLRPDPELPVGRALELAESVLDPEP
                     ADRPLTDDVTAAAALLDRFTEIWRGSES"
     gene            4662..5699
                     /db_xref="GeneID:41540569"
                     /locus_tag="SAVERM_RS18110"
                     /old_locus_tag="SAV_3505"
                     /old_locus_tag="SAVERM_3505"
     CDS             4662..5699
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540569"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128500.1"
                     /locus_tag="SAVERM_RS18110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3505"
                     /old_locus_tag="SAVERM_3505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_037644895.1"
                     /transl_table=11
                     /translation="MIQFDAVHKRFPNGTTAVHDLSLEMPEGGVTVLVGSSGCGKTTTL
                     RMINRMVDPTSGTIRVGGRDILEQDAAELRRSIGYVIQQSGLFPHRTVLDNIATVPLLL
                     GWGRRKARARAAELLDTVGLAADAGRRYPHQLSGGQQQRVGVARALAADPPVLLMDEPF
                     GAVDPVVRTQLQDELLRLQKELSKTIVFVTHDIDEAVRLGDQIAVFRTGGHLVQCASPA
                     ELLARPADDFVADFLGAERGLKLLSLTTLADVPQGPAPEGGAWTLVLDEARRPQHWRSK
                     DGAELPVRPLRDRDSLLAALNESVASPNGLTVRVDADGVLTGVSSRDDIHEHAGRAHSE
                     ASVAA"
     misc_feature    complement(4671..4684)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.64"
                     /tool="antismash"
     gene            5696..6337
                     /db_xref="GeneID:41540570"
                     /locus_tag="SAVERM_RS18115"
                     /old_locus_tag="SAV_3506"
                     /old_locus_tag="SAVERM_3506"
     CDS             5696..6337
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540570"
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381984.1"
                     /locus_tag="SAVERM_RS18115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3506"
                     /old_locus_tag="SAVERM_3506"
                     /product="ABC transporter permease"
                     /protein_id="WP_010984937.1"
                     /transl_table=11
                     /translation="MSVDWSWIGDHTDDLTGLTLSHLQAALTAVFFGLLISLPLAVIAH
                     RIRPLRGFLLGLSNVLFTIPSIAIFVLLLPVSGLTRTTTVIGLTVYTLVVLLRNTVEGL
                     DSVPVKTKEAAKAMGTRPLRTLLTVELPLALPVIMAGVRIATVMSISLVSVATYIGDGG
                     LGQLFTDGFQRNFPTPVIVGVVLTILLALVADALLVAVQYALTPWKRRRA"
     gene            6337..7035
                     /db_xref="GeneID:41540571"
                     /locus_tag="SAVERM_RS18120"
                     /old_locus_tag="SAV_3507"
                     /old_locus_tag="SAVERM_3507"
     CDS             6337..7035
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540571"
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436371.1"
                     /locus_tag="SAVERM_RS18120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3507"
                     /old_locus_tag="SAVERM_3507"
                     /product="ABC transporter permease"
                     /protein_id="WP_037644894.1"
                     /transl_table=11
                     /translation="MYELFKNLGAWLVSGDQWTGPDGIAHRLAEHLQYSLLATLVAAAI
                     ALPVGLLIGHTGRGAFLAINLASFGRALPTVGLVVLVFLASGLSMWPVYIALVALAVPA
                     IVTNTYAGMTAVDPDVKDAARGQGMRWHQVLFQVELPLALPLIMTGLRLALIQVVATAT
                     IAAYVSFGGLGRYVFDGLAQRDLVQVLGGAVLVAAVAVVLDLALSALQRFLFLPHSRLR
                     SSGGTPTRTA"
     gene            7056..7994
                     /db_xref="GeneID:41540572"
                     /locus_tag="SAVERM_RS18125"
                     /old_locus_tag="SAV_3508"
                     /old_locus_tag="SAVERM_3508"
     CDS             7056..7994
                     /codon_start=1
                     /db_xref="GeneID:41540572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128497.1"
                     /locus_tag="SAVERM_RS18125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3508"
                     /old_locus_tag="SAVERM_3508"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_010984939.1"
                     /transl_table=11
                     /translation="MNRRTLLGGLFAAASVPALAACSSGITSLDSQGSGGSGGGSSKGG
                     VIIGTANFTENQVLGHLYAAALEAAGVRTTVRPNLGTREILIPALRGGDIDLLPEYQGA
                     LLHYLAPKATATEEGAMQNALTVALPSGLQVLPYGMAEDSDAFVVTRATAKKYGLSSLA
                     DLKKQNGELVIGAAAEVKKRQVGVVGLKDVYGVEFKEFKSLDSSGPLVKGALRKGDVDV
                     ANLFTTDTDIQANDWVVLSDPRNLVPGQHVVPLIADRKADSTVRRALAELGNVLTTAQL
                     TELNRQVDKDKKDPEDVANAYAEQHGLVKKK"
     gene            8105..8521
                     /db_xref="GeneID:41540573"
                     /locus_tag="SAVERM_RS18130"
                     /old_locus_tag="SAV_3509"
                     /old_locus_tag="SAVERM_3509"
     CDS             8105..8521
                     /codon_start=1
                     /db_xref="GeneID:41540573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004987154.1"
                     /locus_tag="SAVERM_RS18130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3509"
                     /old_locus_tag="SAVERM_3509"
                     /product="hypothetical protein"
                     /protein_id="WP_037644893.1"
                     /transl_table=11
                     /translation="MDARDAELKKELDATLHARRELGDEYESALVDSFLEKVDQRIDGA
                     VDRRVRRQLAEQQMVVARGARSPQATDSWGERFGFGIVSLVLAIPLSAIGATAHLPGLL
                     ITWMGIVGVNVVQAMRVFPSFGRRGDKPEPDWEG"
     gene            complement(8920..10314)
                     /db_xref="GeneID:41540574"
                     /locus_tag="SAVERM_RS18135"
                     /old_locus_tag="SAV_3510"
                     /old_locus_tag="SAVERM_3510"
     CDS             complement(8920..10314)
                     /EC_number="4.2.1.22"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540574"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066696.1"
                     /locus_tag="SAVERM_RS18135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3510"
                     /old_locus_tag="SAVERM_3510"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_010984941.1"
                     /sec_met_domain="PALP (E-value: 7.9e-71, bitscore: 237.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFHDSMISLVGNTPLVRLNSVTAGIQATVLAKVEYFNPGGSVKD
                     RIALRMIEAAEESGALQPGGTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKVSTDKIN
                     VLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGP
                     ELWEQTEGKITHFVAGVGTGGTISGTGRYLKDASEGRVQVVGADPEGSVYSGGSGRPYL
                     VEGVGEDFWPTAYDRTVADEIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALRVA
                     ERLGPDDVVVVLLPDSGRGYLSKIFNDEWMADYGFLEDSGPSARVADVLSDKAGGSIPS
                     LVHMHPDETVGEAIEVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFTQR
                     ASLQDPLEKHMSAPLPQVGSGEPVGDLMSVLGTADAAIVLVEGKPTGVVSRQDLLSFLA
                     KGGGKQ"
     misc_feature    10282..10297
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.09"
                     /tool="antismash"
     misc_feature    complement(10377..10388)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(10426..10442)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            10460..11500
                     /db_xref="GeneID:41540575"
                     /locus_tag="SAVERM_RS18140"
                     /old_locus_tag="SAV_3511"
                     /old_locus_tag="SAVERM_3511"
     CDS             10460..11500
                     /codon_start=1
                     /db_xref="GeneID:41540575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034486.1"
                     /locus_tag="SAVERM_RS18140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3511"
                     /old_locus_tag="SAVERM_3511"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_010984942.1"
                     /transl_table=11
                     /translation="MTSLSRARVARRIAAGAAYGGGGIGLVGAATIGVVLAEVQLAKRH
                     VGNGSAPHPPSAEGRYGYAYTVPGEPPLRLTMLGDSTAAGQGVRRSGQTPGALLASGLA
                     AVAERPVVLRNVALPGAQSDDLDRQVGLVLGASEQVPDVCVIMVGANDVTHRMPATRSV
                     RHLAAAVRRLRTAGAEVVVGTCPDLGTIEPVQQPLRWLARRASRQLAAAQTIGAVEQGG
                     RTVSLGDLLGPEFAANPRELFGPDHYHPSAEGYATAAMAILPTVCAALGLWPAEEERPD
                     VSRREGFLPVARAAAEAASEPGTEVTAAMPTGPRGPWALLKRRRRRRLPAADATAPATP
                     ARETSA"
     gene            11727..12947
                     /db_xref="GeneID:41540576"
                     /locus_tag="SAVERM_RS18145"
                     /old_locus_tag="SAV_3512"
                     /old_locus_tag="SAVERM_3512"
     CDS             11727..12947
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540576"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125100.1"
                     /locus_tag="SAVERM_RS18145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3512"
                     /old_locus_tag="SAVERM_3512"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_037644890.1"
                     /transl_table=11
                     /translation="MPEAVIVSTARSPIGRAFKGSLKDLRPDDLTATIIQAALAKVPEL
                     DPKDIDDLMLGCGLPGGEQGHNLGRIVAVQMGMDHLPGCTITRYCSSSLQTSRMALHAI
                     KAGEGDVFISAGVEAVSRSVKGNSDSLPDTHNPLFAEAEARTAAVAESAGASWHDPRED
                     GLIPDAYISMGQTAENLARIKGVTRQDMDEFGVRSQNLAEEAIKNGFWEREITPVTTPD
                     GTVVSKDDGPRAGVTLEGVQGLKPVFRPDGLVTAGNCCPLNDGAAALVIMSDTKARELG
                     LTPLARIVSTGVTGLSPEIMGLGPVEASKQALRRAGLTIDDIDLVEINEAFAAQVIPSY
                     RDLGIDLDKLNVNGGAIAVGHPFGMTGARITGTLINSLQFHDKQFGLETMCVGGGQGMA
                     MVIERLS"
     misc_feature    13058..13067
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     misc_feature    complement(13060..13073)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.03"
                     /tool="antismash"
     gene            13266..14054
                     /db_xref="GeneID:41540577"
                     /locus_tag="SAVERM_RS18150"
                     /old_locus_tag="SAV_3513"
                     /old_locus_tag="SAVERM_3513"
     CDS             13266..14054
                     /codon_start=1
                     /db_xref="GeneID:41540577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005485749.1"
                     /locus_tag="SAVERM_RS18150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3513"
                     /old_locus_tag="SAVERM_3513"
                     /product="hypothetical protein"
                     /protein_id="WP_037644889.1"
                     /transl_table=11
                     /translation="MPIALLLTTAATAVVGVAVLRTLQSLRRQIAALHTELTESRAASA
                     RGLVPAARSTADAEEIRAAVAEALAEERERELAEARAFWAAQEARDISDAPSLLGLPDS
                     DLFLPRQSDFMGLEHDSLEPVAEPGLEADELSGESPELAAARRRHPSHPDFVPVQSPVV
                     GDHERTVTCLEELAESRTELADIRPGPLGTLDVYVFADGTTLCMTPGHRDTAERLSAAL
                     RAGDTPVLLGGSGISGAYALTFACGEETVYVLADRVIASL"
     gene            complement(14097..14408)
                     /db_xref="GeneID:41540578"
                     /locus_tag="SAVERM_RS18155"
                     /old_locus_tag="SAV_3514"
                     /old_locus_tag="SAVERM_3514"
     CDS             complement(14097..14408)
                     /codon_start=1
                     /db_xref="GeneID:41540578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004987138.1"
                     /locus_tag="SAVERM_RS18155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3514"
                     /old_locus_tag="SAVERM_3514"
                     /product="hypothetical protein"
                     /protein_id="WP_010984945.1"
                     /transl_table=11
                     /translation="MVDTTPLTRAVDHFADLLRAAPQSRLQRSAAAEALGLARELALRA
                     QRLEDPAAEPREMPDAGMFAAADQITVAGRDLALVLSNEEELAEAVTLVVEAQKRAGV"
     gene            14513..14743
                     /db_xref="GeneID:41540579"
                     /locus_tag="SAVERM_RS18160"
                     /old_locus_tag="SAV_3515"
                     /old_locus_tag="SAVERM_3515"
     CDS             14513..14743
                     /codon_start=1
                     /db_xref="GeneID:41540579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004930470.1"
                     /locus_tag="SAVERM_RS18160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3515"
                     /old_locus_tag="SAVERM_3515"
                     /product="DUF4287 domain-containing protein"
                     /protein_id="WP_010984946.1"
                     /transl_table=11
                     /translation="MSQVFSAETHRNLLARIPHCTGREVSDWLRTVDEGPALFRFEEKV
                     SWLRAEHNLAYGHAKAIIHEYDLRRAARKLL"
     gene            complement(14842..15723)
                     /db_xref="GeneID:41540580"
                     /locus_tag="SAVERM_RS18165"
                     /old_locus_tag="SAV_3516"
                     /old_locus_tag="SAVERM_3516"
     CDS             complement(14842..15723)
                     /codon_start=1
                     /db_xref="GeneID:41540580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003061.1"
                     /locus_tag="SAVERM_RS18165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3516"
                     /old_locus_tag="SAVERM_3516"
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="WP_010984947.1"
                     /transl_table=11
                     /translation="MRSSNPVFSRRGFSRDNGYAGFNTAPPAGGPAVGTQANPYAQQGG
                     NPYAQNPYAQQGQQYGAPPQAPVSTGRMTMDDVVMRSAMTLGTVAVGAILAWAVLPVTS
                     TSYALAIGAALIAFVLAMVQSFKRTASPALILAYAAFEGVFLGVISEMFNSQWSGAPFQ
                     AVLGTMAVAGATLLVYKAGWIRVTARYARIGMAIAIAFILVMAVNLLLVVFGVAPDGGL
                     RSMGPLGAVVGIIAILLGAFFLTLDFKQIEDGIAYGAPREEAWLAAFGLTMTLVWIYVE
                     MLRLVAIFSSND"
     misc_feature    complement(15709..15724)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            complement(<15985..17151)
                     /db_xref="GeneID:41540581"
                     /locus_tag="SAVERM_RS18170"
                     /old_locus_tag="SAV_3517"
                     /old_locus_tag="SAVERM_3517"
                     /pseudo=""
     CDS             complement(<15985..17151)
                     /codon_start=1
                     /db_xref="GeneID:41540581"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975727.1"
                     /locus_tag="SAVERM_RS18170"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3517"
                     /old_locus_tag="SAVERM_3517"
                     /product="4-hydroxybenzoate 3-monooxygenase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTTVGIIGAGPAGLLLARLLRNAGIDSVVLESRDRAYVERRQRA
                     GILEQGTVDVLRAAGAGERMDREGLRHDGIELRFDRRRHRVDFPALAGGRAVMVYAQTE
                     VCKDLIALQLEEGGPLLFGAEALAVEGAGTERPRVPFTHEGREDVLECDYVVGCDGFRG
                     VARQAVPAEVSRVFERTYPFGWLGVLADVAPSHDELVYARHERGFALLSMRSPAVSRLY
                     LQVPEGTDAEAWADDEIWAELERRFETDDAWRLERGPITQKSVTPMRGYVHEPMRHGRL
                     FLAGDAAHIVPPTGAKGLNLAVGDVVTFARALTHLKETGSGERLDAYSATCLRRVWQAE
                     RFSYDMTTLLHRPPAATPFEERVQLARLERITSSRAAEADLAEGYTGSP"
     gene            complement(17298..18179)
                     /db_xref="GeneID:41540582"
                     /locus_tag="SAVERM_RS18175"
                     /old_locus_tag="SAV_3518"
                     /old_locus_tag="SAVERM_3518"
     CDS             complement(17298..18179)
                     /codon_start=1
                     /db_xref="GeneID:41540582"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAVERM_RS18175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAV_3518"
                     /old_locus_tag="SAVERM_3518"
                     /product="hypothetical protein"
                     /protein_id="WP_037644887.1"
                     /transl_table=11
                     /translation="MLRRWTRFVAGSYPPLPSVLFAFLWAYGVTGLFAAVQPQSPPWRP
                     GTGTFTAAVTLTVTLLLMRAVDDIRDLAYDRAFHPKRPLAAGTVRMKDLLVLCAAGAVL
                     VLALNAGSPTALAVLAAQLGYCGLFLTVDRLLGWPPGDRLFLSLLFSFPAQLLLHVYLY
                     ARYLHDTSSGPGREGVLAIVITVLVTVHMEFAKKITRRTRPGERSYVDALGLGGTVAVA
                     LIAPVLSVLLLMTQARPVALLTPLALLPLLLPARAGWRFWRTRTPRWPAASPAYYVLST
                     FACYLALSLTYG"
     gene            complement(18173..19585)
                     /db_xref="GeneID:41540583"
                     /locus_tag="SAVERM_RS18180"
                     /old_locus_tag="SAV_3519"
                     /old_locus_tag="SAVERM_3519"
     CDS             complement(18173..19585)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540583"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="SAVERM_RS18180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3519"
                     /old_locus_tag="SAVERM_3519"
                     /product="cytochrome P450"
                     /protein_id="WP_010984950.1"
                     /sec_met_domain="p450 (E-value: 2.6e-24, bitscore: 84.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGASARCPFSGAGGGTDVLPLPADPGTAAGAPAPGPPDAPAAPA
                     PRTADRSAPHAADPHAPSTADLPRFPFPGLSGIPLDPVLLDRYRGEPLVPVGLANGREA
                     LLVTRYADVRTVLSDDRFSREAWANGTLFARRSGALALVTSDAPTHTRRRSRVQSRFTH
                     RRAEEDRPRIARIAAELLDSLQAADTGRPVDLIAEFTTPFPYRVICEMLGVPVADLDRL
                     LPSVTVMMSAGRFSADEAARAHEVMYGYFFGQLAARREAIAAGCPGDDLLTSLLSAPRE
                     TRLSDEEIVVFGFGLMMAGGETTASHLAMCVLQVLGTPGLADRLRRDASAVPAVVEELL
                     RWVWFAGTGGQPHVALEDVELAGRVLPAGQVVIPLTDAANRDPGVFPDADEFRPDRAPN
                     PHIGFGHGRHMCLGAAHARVELQEGLTAVLERLDHLELAVEPAELRWRDQMFMRGVWEL
                     PVRWHTKEDGRC"
     gene            complement(19582..20004)
                     /db_xref="GeneID:41540584"
                     /locus_tag="SAVERM_RS18185"
                     /old_locus_tag="SAV_3520"
                     /old_locus_tag="SAVERM_3520"
     CDS             complement(19582..20004)
                     /codon_start=1
                     /db_xref="GeneID:41540584"
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="SAVERM_RS18185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3520"
                     /old_locus_tag="SAVERM_3520"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_197586458.1"
                     /transl_table=11
                     /translation="MTVSQAEGTMTVARWIGSLEAGWRARDAEAIAALFTDDAVYHQGP
                     YGAPHTGRAAVAEHWRGTLSRQKDAKMWFGEPLVSGRRAAVEWWCVLYDPATGTPRNAA
                     GCLALRFAPDGRCESLHEYWHGAPDQALEPAEGWLR"
     cand_cluster    19821..30708
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    19821..30708
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[24820:25708](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(24821..25708)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            complement(20001..21086)
                     /db_xref="GeneID:41540585"
                     /locus_tag="SAVERM_RS18190"
                     /old_locus_tag="SAV_3521"
                     /old_locus_tag="SAVERM_3521"
     CDS             complement(20001..21086)
                     /codon_start=1
                     /db_xref="GeneID:41540585"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.4"
                     /locus_tag="SAVERM_RS18190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3521"
                     /old_locus_tag="SAVERM_3521"
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="WP_010984952.1"
                     /sec_met_domain="ksIII (E-value: 6.3e-78, bitscore: 260.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVDNLHIAGLGCYLPRPYPAERAVAEGRYEAAEHRNGGWTGAAV
                     AGNISPPEMAVKAARTALERSGHPAADIALVLHASLHEQGPELWTPHQYVLRHAVGTQV
                     PAMEVRQGCNAALGALELAHGYLSADPARAAALVTAAENFGTERVDRWRYQAGARMKRP
                     SILGDAATAVVLSSRGGFARVRSIVSASLPELEEMNRPRGPLFPPNRTRTGRIDLVARV
                     LDYAHDNPGAATLARKSLDAGRTEIALRAIEDAGLRPSDITRVTHVLSGGPEYIRAVLE
                     PLGIDPARGVLDFGRHLGHMTTSDQLAALHHLVETRQVVEGDRVLMINNSFGVSLFGAV
                     VEITGNPSWATGSPSAYKEWK"
     gene            complement(21090..24179)
                     /db_xref="GeneID:41540586"
                     /locus_tag="SAVERM_RS18195"
                     /old_locus_tag="SAV_3522"
                     /old_locus_tag="SAVERM_3522"
     CDS             complement(21090..24179)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540586"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013491.4"
                     /locus_tag="SAVERM_RS18195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3522"
                     /old_locus_tag="SAVERM_3522"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_010984953.1"
                     /sec_met_domain="PPDK_N (E-value: 1.4e-43, bitscore: 148.2,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHTVHHPPSTGSTGRGTTDAGAPASLDTHLAGPVDTHLAGPAAD
                     ALADPVQVGHKFSRQHTMRRAGLPVPAFFVLTAEAFAASVPVPAGFPGTGASAGDLMAW
                     ARAARDRVRAVRVPAELAGRILAAFDELAGPDGLVAVRGCTAAQADGSGEDGADDPFAG
                     LSDSYLYVRRDAVLDRVVDCWSSAYNPEAVLYRVRRGVDVTAVRVAVGVQRMVPGVRSF
                     VMFTRDPRGGAQQAVVAAAHGIGEGIVQEKADIDHFFVNRADGAVRGELAVKSVMVGLD
                     PARADEGPVVLPVPAPLARKAVLSDADVRRVGALAARAEELFGGPQDIEGTITSDGAIH
                     LVQARPVVQTGSVVQTGSVVQTGPVPGEGAVPGAGAVPGAGAAPGDEAVPPVPWTNHNL
                     TESFPGVTSALTYSQARVFYRTGFADFYRRVGVPKRSLRRNQHHLSRMIGHLDGRVYYR
                     LDAWFALHGQIPGFELIRPMWQRSLGFTQPPDHARPDEGDRRRAWGEVLRASPRLGWAY
                     VTQPRRLRQFLRWWDELMAQWPSFEDCTADELVARYRTMWAEAEHRWGITMVSSYFALV
                     ALTCADSLLKRWAPEGSALLPRLLGGGRPNRTLASVRSSIALAERVAADPALRTAVLER
                     PEREVWEEIASSVHGEAVAEEFDRHLRTYGDRALHDLKLEVRTPRQEPWQIVPALRPFI
                     TQGLTVAANEADEAAARRAARHALREACPNPLRRAVLSGVLASLRFSVKAREDTRFCRS
                     QLYGVSREVMWRLAERLVEAGMLDRASDIVHLQAEEVLGAFDGTLPETDLRAVARRREA
                     RQDARAATPDPPAYFTVPGGLPVPVALASRRDTRPRAGLARDGVLRGIASSSGRARGRA
                     LVVRDTRVPPEQCVDRILIAKETDPGWLALMMAARGIVVERGSLVSHTAISGRLLGVPT
                     VVAVTDAMTAVPDGAWVEIDGDAGTVRPLTAAEAAQCEAAEAARRDADDADDADDAAHR
                     KADDATASGRDHSDSAAPGRGDPDGTAPGHDGTTAARGEA"
     gene            complement(24183..24824)
                     /db_xref="GeneID:41540587"
                     /locus_tag="SAVERM_RS18200"
                     /old_locus_tag="SAV_3523"
                     /old_locus_tag="SAVERM_3523"
     CDS             complement(24183..24824)
                     /EC_number="2.1.1.100"
                     /EC_number="2.1.1.334"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540587"
                     /inference="COORDINATES: protein motif:HMM:NF016107.4"
                     /locus_tag="SAVERM_RS18200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3523"
                     /old_locus_tag="SAVERM_3523"
                     /product="isoprenylcysteine carboxylmethyltransferase
                     family protein"
                     /protein_id="WP_010984954.1"
                     /transl_table=11
                     /translation="MNQRLVVLALRALLPVTCAVFVTAIGLLLTDHASTPQLAGALFAG
                     LYVLWVLAEARITVRHPSQSAAENSTLLPYALARAGTGMSAVLWPLPWQGWSAWLVVPV
                     VVFTAAVALRLVAIRTLGRFYSHHVVRYSDHSVVTHGPYRHVRHPAYTGMLLANAAFVS
                     FFLNPLSVLFLLALCAVVTWRVRVEERVLWEVPGYAGYAGGRARLLPGVW"
     gene            complement(24821..25708)
                     /db_xref="GeneID:41540588"
                     /locus_tag="SAVERM_RS18205"
                     /old_locus_tag="SAV_3524"
                     /old_locus_tag="SAVERM_3524"
     CDS             complement(24821..25708)
                     /codon_start=1
                     /db_xref="GeneID:41540588"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015700.4"
                     /locus_tag="SAVERM_RS18205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3524"
                     /old_locus_tag="SAVERM_3524"
                     /product="AfsA-related hotdog domain-containing protein"
                     /protein_id="WP_159029002.1"
                     /sec_met_domain="AfsA (E-value: 1.1e-07, bitscore: 30.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHIETTREEERNGSRVGLLPPPAPSPGGDSWLTELTVDRRDPF
                     FFDHPLDHVPGMLLVCGMANAVRDRIDVPPGLRAKWVVNFRVMPELSPELVLYAAPEEK
                     GRRPLRVTQGPAVVSDGWFVLTPDSDPVRPSAAGARREAPAQASLVHRTRPANVMIGEP
                     RATDGLVTAPVLVPASWHTLASRRAGLRSVKSVIEAGRQFATWLSHRVGGWPPEVQMLW
                     LRLTADLPLDLPASVPLSLRWRQVRMSDDKARLTFEVVAGEGEGVTVGSLIYVSKGLSP
                     DGYRAFRADREAAA"
     misc_feature    complement(25478..25480)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(25698..25711)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            26129..26971
                     /db_xref="GeneID:41540589"
                     /locus_tag="SAVERM_RS18210"
                     /old_locus_tag="SAV_3525"
                     /old_locus_tag="SAVERM_3525"
     CDS             26129..26971
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540589"
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971212.1"
                     /locus_tag="SAVERM_RS18210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3525"
                     /old_locus_tag="SAVERM_3525"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_010984956.1"
                     /transl_table=11
                     /translation="MILVTGATGVVGRQVAHTLARSGRVRLLVRDPARLTVEGPGVEVA
                     TGAYEDHASLLRALKGVEAAFLVTVDPGGQEDGRFLRAAVAADVRHVVKLSSYAAGEDD
                     ADDLITRWQRKCEETLRSSGLDWTLLRPRAFMSNTLSWADSIRREGTVRALYPGSENAC
                     VDPRDIAEVAVTALTSPGHEGRVYPLTGPEAVSAEQQTRHLAAVLGRPLVCRELTPQQA
                     AARWARRYPPKVVHALVLSAQRQLLGRKTTTDPTFARVTGHPPRSYRQWATDHRNAFA"
     misc_feature    complement(27024..27039)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     tRNA            complement(27155..27237)
                     /anticodon=(pos:complement(4362661..4362663),aa:Leu,
                     seq:taa)
                     /db_xref="GeneID:41540590"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="SAVERM_RS18215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="SAV_t15"
                     /old_locus_tag="SAVERM_t15"
                     /product="tRNA-Leu"
     gene            complement(27155..27237)
                     /db_xref="GeneID:41540590"
                     /locus_tag="SAVERM_RS18215"
                     /old_locus_tag="SAV_t15"
                     /old_locus_tag="SAVERM_t15"
     misc_feature    complement(27309..27325)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.04"
                     /tool="antismash"
     gene            27660..28430
                     /db_xref="GeneID:41540591"
                     /locus_tag="SAVERM_RS18220"
                     /old_locus_tag="SAV_3526"
                     /old_locus_tag="SAVERM_3526"
     CDS             27660..28430
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540591"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004987131.1"
                     /locus_tag="SAVERM_RS18220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3526"
                     /old_locus_tag="SAVERM_3526"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010984957.1"
                     /transl_table=11
                     /translation="MTSTPLADRTTAVAARATELSKVYGQGETQVVALDRVTADFRQAE
                     FTAIMGPSGSGKSTLMHCVAGLDTFSSGSVRIGDTELGSLKDKQLTKLRRDKIGFIFQA
                     FNLLPTLTALENITLPMDIAGRKPDKQWLDNVIQMVGLSGRLSHRPAQLSGGQQQRVAV
                     ARALASKPDIIFGDEPTGNLDSRSGAEVLGFLRNSVRELGQTVVMVTHDPVAAAYADRV
                     VFLADGRIVDEVHGPTADAVLDRMKQFDAKGRTS"
     gene            28504..31032
                     /db_xref="GeneID:41540592"
                     /locus_tag="SAVERM_RS18225"
                     /old_locus_tag="SAV_3527"
                     /old_locus_tag="SAVERM_3527"
     CDS             28504..31032
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540592"
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382556.1"
                     /locus_tag="SAVERM_RS18225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3527"
                     /old_locus_tag="SAVERM_3527"
                     /product="ABC transporter permease"
                     /protein_id="WP_010984958.1"
                     /transl_table=11
                     /translation="MFRTALRTVLAHKARLVMTVLAVMLGVAFVSGTLVFTNTISDAYQ
                     KSSAKGFDQVDVAIQAESRQDEGDTIAERPKLTQALLDKAAEVPGAGSAIGVVNGFTAI
                     ADQDGKLVGNGFQSQGGNYWGTKDPRYPLTVGHAPRGKNEIALDARTAERAGYKVGDTV
                     RLSVDGPVLTPKVTGIFTTDDGNVAAGGSLALFDTATAQQLFHKAGEYDEIDVKAASGT
                     SQIALRNALDEVVPKDVASTTTGKQLADDQATQIASAMSGMKTGLLVFAGIALFVGTFI
                     IANTFTMLVAQRTKELALLRAVGASRRQVTRSVLIEAFVVGAVAAVTGLAAGIGIGAGM
                     RSLMGTLGATVPDGPLVISPGTVATALLVGILITMLAAWLPGRRAAKIPPVAAMSSVHA
                     KATTKSLVLRNTLGALFSAAGIAVVLYATTLDGSDGQAPMGLGAVLLIIGVFILTPLLS
                     RPLIAAAAPVLRIFGVSGKLARQNSVRNPRRTAATASALMIGLTLITGMTVMAGSLQTS
                     IDKMASSAIKADYVVSMANGNYLSTDVDKKLSATDGVTATSPLRNAPSRIDGETEYLTG
                     VNGRSINDLTDLTVQDGAFKVGGTQVVVDDETAASHHWTAGSRFTASFEDGKKQRLTVT
                     GVYQSTEMMRGIMLDNATLTPHLTDPSDMQVMVKTSAGASGPVKDRLEKALGDNPAIKV
                     QDKKDISNDIAQMFTLMLNMLYGLLAMAVIVAVLGVINTLAMSVFERSQEIGMLRAIGL
                     DRKGIKRMVRLESLVISLFGGVLGIGLGVFFGWAAGELLGTKMATYELVLPWGRMALFL
                     LLAAAVGVLAALWPARRAARLNMLTAIKSE"
     gene            complement(31100..32389)
                     /db_xref="GeneID:41540593"
                     /locus_tag="SAVERM_RS18230"
                     /old_locus_tag="SAV_3528"
                     /old_locus_tag="SAVERM_3528"
     CDS             complement(31100..32389)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (169-267). E-value: 2.2e-19. Score:
                     60.8. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS18230_oMT.1"
                     /codon_start=1
                     /db_xref="GeneID:41540593"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329947.1"
                     /locus_tag="SAVERM_RS18230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3528"
                     /old_locus_tag="SAVERM_3528"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_010984959.1"
                     /sec_met_domain="PCMT (E-value: 8e-06, bitscore: 24.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAALRLKSLLDQLLGAPLPLRIHAWDGSEAGPPGAPTLVVRNR
                     RALRRLLWKPGELGLARAWVAGDVTVRGDLYAVLDLIAGLLWERRDDARTLTEALRDPD
                     VRAAVSGLVRMAGPPLPPAPPREEVRRRGHLHTKRSDRRAISHHYDVGNDFYEIVLGPS
                     MVYSCAYWATPDGTLEDAQRDKLELVSRKLGLTPGQRLLDVGCGWGSMAIHAAREHGVS
                     VVGITLSQEQAAYARKRVADEGLTDRVEIRVQDYRDVTDGPYDAISSIGMAEHVGAERY
                     LDYARDLYALLKPDGRLLNHQIARRPQLDESTYSVDEFIDAYVFPDGELAPIGSTVTQL
                     ERAGFEVRDVESLREHYALTLRRWVANLEAQWVRGVRLTSPGRARVWRLYMAACALAFE
                     HNRIGVNQVLAVRTPESGASGIPLRARTWN"
     aSDomain        complement(31589..31882)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS18230_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.20E-19"
                     /label="SAVERM_RS18230_oMT.1"
                     /locus_tag="SAVERM_RS18230"
                     /protein_end="267"
                     /protein_start="169"
                     /score="60.8"
                     /tool="antismash"
                     /translation="YWATPDGTLEDAQRDKLELVSRKLGLTPGQRLLDVGCGWGSMAIH
                     AAREHGVSVVGITLSQEQAAYARKRVADEGLTDRVEIRVQDYRDVTDGPYDAI"
     gene            complement(32594..33985)
                     /db_xref="GeneID:41540594"
                     /locus_tag="SAVERM_RS18235"
                     /old_locus_tag="SAV_3529"
                     /old_locus_tag="SAVERM_3529"
     CDS             complement(32594..33985)
                     /EC_number="1.6.5.-"
                     /codon_start=1
                     /db_xref="GeneID:41540594"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059843.1"
                     /locus_tag="SAVERM_RS18235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3529"
                     /old_locus_tag="SAVERM_3529"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_048894565.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.9e-44, bitscore:
                     149.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTERPRILVVGGGYVGLYAARRILKKMRYGEATVTVVDPRSYM
                     TYQPFLPETAAGSISPRHVVVPLRRVLPKAEVLTGRVTTIDQDRKVATIAPLVGEAYEL
                     PFDYLVIAMGAVSRTFPIPGLAEQGIGMKGIEEAIGLRNHVLEQLDKADSTTDEEVRRK
                     ALTFVFVGGGFAGAETIGEVEDMARDAAKYYNNVSREDMRFILVDAADKILPEVGPKLG
                     QYGKEHLESRGVEIYLSTSMDSCVDGHVVLKNGLEVDSSTIVWTAGVKPNPVLSRFGLP
                     LGPRGHVDTQTTLQVQGTDYIWAAGDNAQVPDMAARKAGVENAWCPPNAQHALRQARVL
                     GDNVVSGMRGFPQKEYAHSNKGAVAGLGLHKGVAMIVMGKMKIKLKGRLAWYMHRGYHG
                     LAMPTWNRKIRVFADWTLQMFLKREVVALGALESPREEFYEAAKPAPAPAAAVAPKTEE
                     KAKAS"
     misc_feature    34294..34309
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            complement(34571..35512)
                     /db_xref="GeneID:41540595"
                     /locus_tag="SAVERM_RS18240"
                     /old_locus_tag="SAV_3530"
                     /old_locus_tag="SAVERM_3530"
     CDS             complement(34571..35512)
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296572.1"
                     /locus_tag="SAVERM_RS18240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3530"
                     /old_locus_tag="SAVERM_3530"
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="WP_010984961.1"
                     /transl_table=11
                     /translation="MTRVAAIDCGTNSIRLLVADAHPETGELVDLDRRMTIVRLGQGVD
                     RTGRLAPEALERTFAACREYAAIIKEHGAEKIRFVATSASRDAENRDEFVRGVIDILGV
                     EPEVITGDQEAEFSFTGATKELTGRDDLAKPFLVVDIGGGSTEFVVGDDHVRAARSVDI
                     GCVRMTERHLVHDGQVVDPPSPDRIEAIRADIDAALDLVEQTVPLHEAHTLVGLAGSVT
                     TISAIAQNLPEYDSVAIHHSRIPYDRVREITEWLLASTHAERAAVPSMHPGRVDVIGAG
                     ALVLLSIMERIGAREVVVSEHDILDGIAWSIA"
     gene            complement(35647..36171)
                     /db_xref="GeneID:41540596"
                     /locus_tag="SAVERM_RS18245"
                     /old_locus_tag="SAV_3531"
                     /old_locus_tag="SAVERM_3531"
     CDS             complement(35647..36171)
                     /codon_start=1
                     /db_xref="GeneID:41540596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436386.1"
                     /locus_tag="SAVERM_RS18245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3531"
                     /old_locus_tag="SAVERM_3531"
                     /product="DUF501 domain-containing protein"
                     /protein_id="WP_010984962.1"
                     /transl_table=11
                     /translation="METPPPTTPRTEPTDADVEAFKQQLGRPPRGLRAIAHRCPCGQPD
                     VVETAPRLPDGTPFPTTYYLTCPRAASAIGTLEANGVMKEMTDRLATDPELAAAYRAAH
                     EDYIARRDSIEVLEGFPSAGGMPDRVKCLHVLVAHSLAAGPGVNPLGDEAIAMLPEWWR
                     KGACVVPAADE"
     gene            complement(36200..36676)
                     /db_xref="GeneID:41540597"
                     /locus_tag="SAVERM_RS18250"
                     /old_locus_tag="SAV_3532"
                     /old_locus_tag="SAVERM_3532"
     CDS             complement(36200..36676)
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382561.1"
                     /locus_tag="SAVERM_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3532"
                     /old_locus_tag="SAVERM_3532"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_037644884.1"
                     /transl_table=11
                     /translation="MAVKDRDRFSTATRLRLLGEQTAARVYRSQTKRQARRSRLTSRAA
                     LLALVLCSLIVALAYPIRQYVSQRAEVADLQRQQERARQRVEQLRDLKARWQDDAYAEQ
                     QIRQRLHYVMPGETGYIVIDPAAAKPARTTQGAADRPWYANVWDGVDKSDASDQ"
     gene            complement(36793..38085)
                     /db_xref="GeneID:41540598"
                     /gene="eno"
                     /locus_tag="SAVERM_RS18255"
                     /old_locus_tag="SAV_3533"
                     /old_locus_tag="SAVERM_3533"
     CDS             complement(36793..38085)
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540598"
                     /gene="eno"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645655.1"
                     /locus_tag="SAVERM_RS18255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3533"
                     /old_locus_tag="SAVERM_3533"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_037644882.1"
                     /transl_table=11
                     /translation="MLVPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGAST
                     GAFEAIELRDGDPNRYQGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDN
                     KGSLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVD
                     IQEFMIAPIGAESFSEALRWGAEVYHTLKKVLKTKGLSTGLGDEGGFAPNLESNRAALD
                     LIIEAIKQAGYIPGEQIALALDVAASEFYKDGKYEFEGKSRSAAEMTEYYEELVSAYPL
                     VSIEDPLYEDDWAGWKVITDKLGDKVQIVGDDLFVTNPERLARGIEEGSANALLVKVNQ
                     IGSLTETLDAVELAQRNGFKCMMSHRSGETEDVTIADLAVAVNCGQIKTGAPARSDRVA
                     KYNQLLRIEEILDDAAEYAGRSAFPRFRSAN"
     misc_feature    complement(38098..38113)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.05"
                     /tool="antismash"
     gene            complement(38421..39104)
                     /db_xref="GeneID:41540599"
                     /locus_tag="SAVERM_RS18260"
                     /old_locus_tag="SAV_3534"
                     /old_locus_tag="SAVERM_3534"
     CDS             complement(38421..39104)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975714.1"
                     /locus_tag="SAVERM_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3534"
                     /old_locus_tag="SAVERM_3534"
                     /product="transglycosylase family protein"
                     /protein_id="WP_010984965.1"
                     /transl_table=11
                     /translation="MLLSSKGKHRRPSKATRAIAIAGVTGAAVAAPLMAAGNASAATAS
                     EWDAVAQCEAGGNWSINTGNGYYGGLQFSASTWAAYGGTAYASTADQASKSEQISVGEK
                     VLAAQGKGAWPTCGTGLSGAANNAGSPAPSTPQQSTPKSSTTQSTEQRASRSDERPAAK
                     TVETPTGKKVKKGDGEYKVVKGDTLSSIAEKKHVAGGWQKLFKLNKDIVDDADFIYPGQ
                     QLHLS"
     regulatory      complement(39109..39288)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(39465..40424)
                     /db_xref="GeneID:41540600"
                     /locus_tag="SAVERM_RS18265"
                     /old_locus_tag="SAV_3535"
                     /old_locus_tag="SAVERM_3535"
     CDS             complement(39465..40424)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41540600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003051.1"
                     /locus_tag="SAVERM_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_3535"
                     /old_locus_tag="SAVERM_3535"
                     /product="transglycosylase family protein"
                     /protein_id="WP_010984966.1"
                     /transl_table=11
                     /translation="MLSGNGRHRRPRQAPALLVAAGVTGSAIAIPLLGATGASAASGTT
                     WDQVAECESGGSWSADTGNGYYGGLQLSQGNWEKYGGLDYAPSADQASRSQQIAVAEKV
                     LAAKGSSPWSTCGIAVGLSQDSGSADVDTGLLGSGSTADSDSGSGISSGLSDSSSSSGS
                     SSAAKDSKGSAKADATPSGSSTSDSSSADAAKSDDSDKSGQNGDASTPSEAESTSSGRH
                     RGDTADESAADGRADDSTGRHASRGSDGSREAAPDAADDAYVVRPGDSLSAIADSLGLR
                     GGWSALYTENEKTVGADPDVIVPGQSLALAAEPGEKQR"
     misc_feature    40503..40514
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    40563..40578
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.81"
                     /tool="antismash"
ORIGIN
        1 gccggtcacc ccggccgcga cgaccccggc cccggacact ccagccccgg ccacctcggc
       61 cggcaccgcc accgcgcgga ccacgccgcc cgcgccgccc gcgcccccgg tagcccctcc
      121 ggcccccaca gccctgccgg cccgcggcac cccgcccctc acactcgccc cgcccgaccc
      181 gctcgccccg cccgacacac ccaccccgcc cgacccgctc gcccatctcg ccctgacgtc
      241 gaccgacccc gacgtctctc tgctgcgtcg gctccgtgac gccctggagg ccctgtgatc
      301 cgcgcgctcc gacagcgtgc cgagaggaga ctactgatgg cggccgaggc cgaagtcctc
      361 gacgaactcc accggttgag gtcccgtgtg ccccagctga ccggtgcgct cgcggccagc
      421 gtcgacggtc tggtcctcgc ccaggacacc cccggcgtcg acccggacag cctggccgcg
      481 ctcacggcgg ccgcgctggg cgtcgcgctg cgggtgacgg acgccaccgg gcagggcgac
      541 ttccgcgagc tgctggtccg cggcgtgcac ggctatgtgg cgacgtacgc cgccggaggc
      601 accgccgtcc tgacgctgct ggcccaggac cgggtcaacg tcggccgcct gcacctggag
      661 ggccgccgcg ccggcacccg gatcggggag ctgatcgagg ccgcggcggc ccgcgccgaa
      721 ccggcgccgc agacacccgc ggccaaggca cccgccaagg ccgtcgccaa gtccgccacc
      781 ccgcggacca gaaccgcgcg cgctcccgcg aaaccccgca ccaccacgaa cgcgcgcacc
      841 accaccacgg aaagctgaaa ggacaccccg tcatgaccaa caccgaaacc gcgttgaaag
      901 aggccctcgc ctccatcgag ggcgcgaccg gagccgccct cgtcgactac accaccggaa
      961 tggcgctcgg cacgatcggc ggcagcaaga gcttcgacct caccgtcgcg gccgcgggca
     1021 acaccgatgt cgtacgcgcc aagctccgca ccatggagca cctcgggctc aagggcgaga
     1081 tcgaggacat cctgatcacg ctgaccgacc agtaccacct gatccggctg atcaccggac
     1141 gtgggggcaa cggcctgttc ctctatctgg tgctggatgc caagcgggcc aacctggcga
     1201 tggcccggca ccagttgaag aggatcgagg cggacctgga ggtctgaccc aggcctacac
     1261 cagtgcgtcg gtgcggcgac gcgccccgcc cggggccgcg tcgcccgccg cgatgcccgt
     1321 gctgcggtag accttgaccg ccttgcccgc cggtcgtccg ccatgtgcgc cgagccagtc
     1381 gacgcgcacc cacagcaggg cgtcgccggc ccgctcgcgc cggccgagcc aggccgcctt
     1441 gagccgcagt ccggtgccga gcccggccag cagcatgccc ccggcggcgg gcacggcgaa
     1501 ggagctgacc agcgcggcca cgaaggcgag cagcagccac cagcgatggc cccggcgcca
     1561 gttgcggacg gtcacggcgc ggtcctggag cacatcgtgc ttgcccgcgc gtgcggccgc
     1621 ggcggccagg gcggtgtacc gcttccggct cccgtacgtc acgacggcgg ccgcgacgag
     1681 gaacagcacg gccccggcca tgacgccgat ccggcgtccg gtcagccccg gtacgagcac
     1741 tccgacgccc gccgcgaacg ccccgcacca ccacaacggc gcggctccgg ccctcaccac
     1801 gacggccacc cgagccagcc cctgccctcc gcgcgccatg ccctgcctcc tcaggtcccc
     1861 gactgtccgc gggcaggcta acgagcgaag gtgagacgaa tctgagaacc acggacgagg
     1921 agaggacggg tccgctcccc cggcatcccc tcgccgaggc ccactccccc gcgacaaccc
     1981 ctccgccgag gcccactccc ccgcgacaac ccctccgccg aggcctactc cacgaacaac
     2041 cccttcgccg ccgcccgcgc gtcgaactcc tccaggcgtg cctgcgcgtc cggcaggtcg
     2101 tcgcacatgg cctccagcag tacccggccg agcagcatgg gggcgcacgc cgtgtcgaag
     2161 gcgaggcccg tgccgacggc ggcgggcagc agcaggtcgg acaccttggc gaccggcgcg
     2221 aacgcggagt ccgcgaccgt gacgacggtc agcccggcct ccctcgcgta cgccagcgtg
     2281 tccacgacct cgcgcggatg ccgcggcagc gcgaagcaca gcagcgcgct cgcccccgcc
     2341 cggacggccg cgtcgatacg gtcctggacc atcgtgccgc cctcgtgcag cagccgtacg
     2401 tccggatgga ccttggcggc gaagtaggcg aagccgtacg cctgggaggc cgccgcccgc
     2461 agcccgagca ccggcagcgg gcgggacgcg gcgagcagcc gcccggcacg cgccagcggt
     2521 cgcgggtcgg ccagcagctc cgccagatgc ttcaggttct cgatctcggc ctcgacggcc
     2581 tgctggtact cgttgtacga ggaggtgtcc ggggcctgtt cggcgggcgc gacctcgcgc
     2641 agatgcttgc gcagcgccgg gtagccgtcg aagccgagcg ccaccgcgaa gcgggtgacg
     2701 gacggctggc tgaccccggc cagctccgcc agctccacgc tcgacaggaa cggcacgtcg
     2761 gcggcgcgcc gcaccatgct gtgcgcgatg cgccgctggg tcggtgtcag ccggtgcccc
     2821 tcgaagagcg cctgaagccg cccggccgga ctgtccgtca tttccgtgtc cctgtccccg
     2881 ctcatgactc gctccccctc cagatctccg tgaaccggtc gagcagtgcg gccgcggccg
     2941 tcacgtcgtc cgtgagcggc cggtcggccg gctccgggtc gagcaccgac tcggcgagct
     3001 ccagcgcccg gcccaccggc agctccgggt cgggccgcag gtcgcgctgg cgcagcgccc
     3061 gtacggcggc gaccagttca cagccgacga cgagacggta cgcgtcgcac gcccgcagcg
     3121 tctggcgtgc cgcgagcgag gcgaagctgg cctgttcctc gacgccccgg gagagtacag
     3181 cgtgcccgag cgaggcgggc gcggagaacg cgcgcagatc gccgagggcg gctccggcgg
     3241 cgtactccag gatcatcacg ccggaggagg cgggctcgtg gtcggcgagg aaggggcgca
     3301 gccgggtgta cgcgggctcg ttcaacgtcg acagcctgga cgtcgacagg cgcgccacct
     3361 gggtgatggc cagcctgaag tggtcgaggg ccagggcgag ttgggcctgg tagaagccgc
     3421 cgtggtggta ggcggccagg tccccggggg agatgagggg gttctcggcg gcggcgttga
     3481 tctcgaccgc gaggaccgct tcgagcgcgt cggccgcctc gtgtgcgggg ccgtggatct
     3541 ggggcagaca gcggaagccg tacgggtcct ggatacggcc gaggggcggg gtcggccggt
     3601 cggcggcgcc gatcaactcc cgcatgatcc gggcgacttc ggcggagccg cggtgcgggc
     3661 gggcggtgtg cacgggggcg gcgtacgcct cgtgcgagcc gtcgaccgcg agcagcgaga
     3721 gcgccgcgac gacctgggtg gcgccgatga gcccgcgcag ctcgtgcagc gcgagcgcgg
     3781 actggccgag ggtgagggcg ttgctgctga tgagcgcgag ggcgtcgttg ttgtcgagga
     3841 gctggggctc cggagcgccg atctcccgcg cggacgcgcc ccgccgaaga gcgcgcacgc
     3901 ctcccgcgta ccgcccaccc gaagcccctg cccccggccc accggaagtc tccgacccca
     3961 accccccgga agtctccgcc cgtcgccacg gatgctcccc cgcgagcgcc agtcccacct
     4021 gggccagggc cgcgatgtcg cccgtgccca ccgagccgaa ctcgttcacg acggggtagg
     4081 ccccgttctc cagcgcctcg cacagcgccg tgaccacggt gggccgcagc cccgcgccgc
     4141 cggccagcaa ctggttgacc cgcacggcca gcatcgcccg cacctgccgc gcgggcagct
     4201 ccgccccgat ggccccggca tggctgcgca gcagccggag tccgtgcccc gcggccgcct
     4261 ccgtgggcac gtcctcgttc cggttcgcgc ccactccggt ggagcggccg tagacccggc
     4321 cggtcgcggc gatctgccgg gccgcgtccc aggactcctc cacccgcttc atcgcttcgg
     4381 tgccgggaac cggccgcgaa gccccgtcgg cgaggcacac gacgtcggag acgccgattc
     4441 cacagccgtc gaggaccacg atcccggtcg acgcggggct cacttccacg gtcgacgtat
     4501 ccacgatccg agacgacatc acgcgcaaac tcccctcaac ccggacatcg gatcttgcct
     4561 ggcggtcata agtaaccagc gcttaacgcc ggaccattga caatctattc agacaccgag
     4621 aactctgcat gacgatatgc aggccgggca agggacacct catgatccag ttcgacgcgg
     4681 tccacaaacg cttcccgaac ggaacgacag cagtccacga tctctccctg gagatgccgg
     4741 aaggcggtgt gaccgtcctc gtcggatcct ccggttgcgg taagacgacc acgctcagga
     4801 tgatcaaccg gatggtcgat ccgacctccg gcaccatccg ggtcggcggc cgggacatcc
     4861 tcgaacagga cgccgccgag ctgcgccgct ccatcggtta cgtcatccag cagtcggggc
     4921 tcttcccgca ccgcacggtg ctcgacaaca tcgccaccgt gccgctgctc ctcggctggg
     4981 gccgccgcaa ggcacgggcc cgggcggccg agctcctcga caccgtgggc ctcgccgccg
     5041 acgccggccg gcggtacccg caccagctct ccggcggcca gcagcagcgc gtcggagtcg
     5101 cccgcgccct cgccgccgac ccgccggtcc tgctcatgga cgagccgttc ggcgcggtcg
     5161 acccggtcgt ccgcacccag ctccaggacg aactcctgcg cctccagaaa gagctgagca
     5221 agaccatcgt cttcgtcacg cacgacatcg acgaggcggt ccggctcggc gaccagatcg
     5281 cggtcttccg caccggcggc cacctcgtgc agtgcgcctc gcccgccgaa ctgctggccc
     5341 gcccggcgga cgacttcgtg gcggacttcc tcggcgccga gcgcggcctc aagctgttgt
     5401 cgctgaccac gctcgccgac gtcccgcagg gccccgcccc cgagggcggc gcctggaccc
     5461 tcgtcctcga cgaggcccgc cggccgcagc actggcgttc gaaggacggt gccgaactcc
     5521 ccgtacgacc gctcagggac cgcgactcgc tgctcgccgc cctgaacgag tcggtcgcct
     5581 ccccgaacgg gctgacggtc cgtgtcgacg cggacggagt cctcaccggg gtgtcgtccc
     5641 gcgacgacat ccacgagcac gcgggccggg cgcacagcga agcgagcgtc gccgcgtgag
     5701 cgtcgactgg tcgtggatag gcgaccacac cgacgacctc accggtctca ccctctccca
     5761 cctccaggcc gccctgaccg ccgtcttctt cggcctgctg atctccctcc cactggcggt
     5821 gatcgcccac cggatccgcc cgctgcgcgg cttcctgctc ggcctgtcga acgtgctgtt
     5881 cacgatcccg tcgatcgcga tcttcgtcct cctcctgccg gtctcggggc tgacccgcac
     5941 cacgaccgtc atcggcctga ccgtctacac cctggtcgtt ctgctgcgga acacggtcga
     6001 gggcctcgac tcggtcccgg tgaagacgaa ggaggccgcc aaggcgatgg gcacccgccc
     6061 gctgcgcacc ctcctcaccg tcgaactccc cctcgccctc cccgtgatca tggcgggcgt
     6121 ccggatcgcg acggtcatgt cgatctccct ggtctccgtg gcgacgtaca tcggagacgg
     6181 cggcctcggc cagctcttca cggacggctt ccagcgcaac ttcccgacgc cggtgatcgt
     6241 gggcgtcgta ctgacgatcc tgctggccct ggtcgcggac gcgctcctgg tggcggtcca
     6301 gtacgcactc accccgtgga agaggcggcg cgcctgatgt acgaactctt caagaacctc
     6361 ggcgcctggc tggtcagcgg cgaccagtgg accggcccgg acggcatcgc gcaccgcctc
     6421 gccgagcacc tccagtactc gctgctcgcc accctcgtcg ccgccgcgat cgcgctgccc
     6481 gtcggcctgc tgatcgggca caccgggcgc ggcgcgttcc tcgccatcaa cctcgcgtcc
     6541 ttcggccgcg cgctgcccac cgtgggcctg gtcgtgctcg tcttcctggc cagcggtctg
     6601 tcgatgtggc cggtgtacat cgcgctggtc gccctcgcgg tcccggcgat cgtgacgaac
     6661 acgtacgcgg gcatgaccgc cgtcgacccg gatgtgaagg acgccgcgcg cgggcagggc
     6721 atgcgctggc accaggtcct cttccaggtg gagcttcccc tcgcgctccc gctgatcatg
     6781 acgggtctga ggctcgcgct gatccaggtc gtcgcgacgg ccacgatcgc cgcgtacgtg
     6841 tccttcggcg gcctgggccg ctatgtcttc gacggcctcg cccagcgcga cctggtccag
     6901 gtcctgggcg gcgcggtgct cgtcgccgcg gtcgccgtcg tcctcgacct ggcgctctcc
     6961 gccctccagc gcttcctctt cctcccccac tctcggcttc gctcgagcgg ggggaccccc
     7021 acccgcaccg cctaggcctc agggaaccca ccgaaatgaa tcgtcgtact ctcctcggcg
     7081 gcctgttcgc ggccgcctcc gtccccgccc tcgccgcgtg cagcagcggt atcacctccc
     7141 tcgacagcca gggaagcggc ggctcgggcg gcggctccag caagggcggg gtcatcatcg
     7201 gcaccgccaa cttcaccgag aaccaggtcc tcggccacct ctacgcggcc gccctggagg
     7261 cggccggcgt caggacgacg gtccggccca acctcggcac ccgcgagatc ctcatccccg
     7321 cgctcagggg aggcgacatc gacctgctcc ccgagtacca gggcgccctg ctgcactacc
     7381 tcgccccgaa ggcgacggcc acggaggagg gcgcgatgca gaacgccctc accgtcgccc
     7441 tcccgtccgg cctccaggtg ctgccgtacg ggatggccga ggactccgac gccttcgtcg
     7501 tcacacgggc gacggcgaag aagtacggcc tgtcctccct cgccgacctg aagaagcaga
     7561 acggcgagct ggtcatcggc gccgccgccg aggtgaagaa gcgtcaggtc ggcgtggtcg
     7621 gcctgaagga cgtgtacggg gtggagttca aggagttcaa gtccctggac tcctccgggc
     7681 cgctggtcaa gggcgccctg aggaagggcg acgtggacgt ggcgaacctc ttcaccaccg
     7741 acaccgacat ccaggccaac gactgggtgg tcctgtccga ccccaggaac ctcgtcccgg
     7801 gccagcacgt cgtcccgctc atcgccgacc gcaaggccga ctccacggtc cgcagggccc
     7861 tcgccgaact cggcaacgtc ctcaccaccg cccagctgac cgagctcaac cgccaggtgg
     7921 acaaggacaa gaaggacccg gaggacgtgg cgaacgcgta cgccgagcag cacgggctgg
     7981 tgaagaagaa gtaggagaag aagcgggaag gggggcctgc gggggtgcgg cccagctcga
     8041 acaggggggc tacccccagt gccgcggcga ccacggcacg cctaccgtga gcgccatgac
     8101 cggtatggat gcccgcgacg ccgaactgaa gaaggaactc gacgccaccc tgcacgcgcg
     8161 cagggagctg ggggacgagt acgagtccgc gctggtggac tcgttcctgg agaaggtgga
     8221 tcagcgcatc gacggcgcgg tcgaccgccg ggtgcggcgt cagctggccg agcagcagat
     8281 ggtggtggcc cgtggcgcac ggtccccgca ggccacggac tcctggggtg agcgcttcgg
     8341 cttcggcatc gtctcgctcg tcctcgcgat ccccctgtcc gcgatcggcg ccaccgccca
     8401 cctccccgga ctcctgatca cctggatggg catcgtgggc gtcaacgtgg tgcaggcgat
     8461 gcgcgtgttc ccgtccttcg gccgccgcgg cgacaagccg gaaccggact gggaaggcta
     8521 ggaccggcct gctgccggga aagtgttgcg cggggaccgc cgcacccccg ttaccggggg
     8581 gcgggacgac ggcggtcccc gcgagggacg cgggccgggt cagggccagg cttacgcgtc
     8641 cgtggcgtcc atggaggtcc gggagccgct ccggaggtcc ttggcgccgt tttcggtgcc
     8701 ggccggggcg gggagccgct cccgccctgc cgacatccac caatgtgccg gacgcgtgtt
     8761 aagcgggtgc tgcgcggacg tgacgcgctc gtaccacttc tacgaagttc cgtgccatgc
     8821 cccgccggac ggacccgaag acccgcccgc cggacggacg gaccggatga gccgcccgcc
     8881 ggacggaccc gaaggtccgt ccggcgggcg gggccgcggc tactgcttgc cgccgccctt
     8941 ggccaggaac gacagcaggt cctggcggct gaccacaccg gtcggcttgc cctcgacgag
     9001 gacgatcgcc gcgtcggccg tgccgaggac ggacatcagg tccccgacgg gctcgcctga
     9061 accgacctgc ggcagcggcg cggacatgtg cttctccagc gggtcctgca aggaggcgcg
     9121 ctgcgtgaac agcgcgtcga gcagctcgcg ttcgacgacc gagccgacga cctcggcggc
     9181 catgacgtcc gggtggccgg cgcccggctt cacgatcggc atctgcgaga cgccgtactc
     9241 gcgcagcacc tcgatcgcct cgccgacggt ctcgtcgggg tgcatgtgga cgagggaggg
     9301 gatggagccg cccgccttgt cgctgaggac gtcggcgacg cgggcgctgg gcccggagtc
     9361 ctcgaggaag ccgtagtcgg ccatccattc gtcgttgaag attttactga ggtacccgcg
     9421 cccgctgtcg ggcagcagca ccacgaccac gtcgtccggc ccgagccgct cggcgacccg
     9481 cagcgcggcg acgacggcca tgccgcagga accgccgacg agcagcccct cctccttggc
     9541 gagccgccgc gtcatctgga aggagtcctt gtcggacacg gcgacgatct cgtccgcgac
     9601 cgtgcggtcg tacgcggtcg gccagaagtc ctcgccgacg ccctcgacga ggtacgggcg
     9661 cccggagccg ccggagtaca cggagccctc ggggtcggcg ccgacgacct ggacgcggcc
     9721 ctcactggcg tccttcaggt aacgcccggt accggaaatg gtcccgccgg tgcccacgcc
     9781 cgcgacgaag tgggtgatct tcccctccgt ctgctcccac agctcggggc cggtggagtg
     9841 atagtgcgaa agggggttgt tcgggttgga gtactggtcc ggcttccacg caccgggcgt
     9901 ctcgcgcacg agccggtccg agacgttgta gtaggagtcg gggtgctcgg ggtcgacggc
     9961 ggtcgggcag accaccacct cggccccgta ggcacgcagc acattgatct tgtcagtgct
    10021 caccttgtcg gggcacacga agatgcactt gtaccccttc tgctgcgcga cgatggcgag
    10081 cccgacaccg gtgtttccgc tggtcggctc gacgatcgtg ccaccgggct gcaaagcgcc
    10141 gctctcctcc gcggcctcga tcatccgcag ggcgatgcgg tccttcacgg aaccgcccgg
    10201 gttgaagtac tcgaccttcg cgaggacggt cgcctgaatg cccgcggtca cgctgttgag
    10261 cctcaccagc ggggtgttgc cgacgagact gatcatcgag tcgtggaatt gcaccgttgt
    10321 ctccggagct gcaaagaagt ggtcgttagg tcccgccagc ctacggcccc ctacacgcgt
    10381 tcacgtgccg ttgagattgg ccgaccgcct ctacggggca agcagtggtt gtacggctac
    10441 aaggaggtgg cggcggcgga tgacgagctt gtcgagggcg agggtggccc ggcgcatcgc
    10501 ggcgggtgcc gcgtacggcg gtggtgggat cggtctggtg ggcgcggcga cgatcggcgt
    10561 cgtgctggcc gaggtgcagc tggccaagcg ccatgtgggc aacggcagtg cgccgcaccc
    10621 gccgagcgcg gagggccgct acggatacgc gtacaccgtc cccggtgaac cgccgctccg
    10681 gctgacgatg ctcggcgact ccaccgccgc cggtcagggc gtacgccgat cgggtcaaac
    10741 tccgggcgct ctgctggcct ccgggctcgc ggcggtcgcc gagcgcccgg tggtgctgcg
    10801 gaacgtggcg ctgccgggcg cccagtcgga cgatctcgac cgccaggtcg gcctggtcct
    10861 cggcgcctcc gaacaggtgc ccgacgtctg cgtgatcatg gtcggggcga acgatgtgac
    10921 gcaccgcatg ccggccaccc gctcggtccg ccatctcgcc gccgcggtac gccggctgcg
    10981 caccgcgggt gcggaggtgg tcgtgggcac ctgccccgac ctgggcacga tcgagccggt
    11041 ccagcagccg ctgcgctggc tggcccgccg cgcctcgcgc cagctggcgg ccgcgcagac
    11101 gatcggggcg gtggagcagg gcgggcgcac ggtgtcgctg ggcgacctgc tcggcccgga
    11161 gttcgcggcg aacccccggg aactcttcgg ccccgaccac taccacccct cggcggaggg
    11221 ctacgcgacc gccgcgatgg cgatactgcc gacggtctgc gcggcgctcg gcctgtggcc
    11281 ggcggaggag gagcgcccgg acgtctcccg ccgcgagggc ttcctgccgg tggcacgggc
    11341 ggcggccgag gccgcgtccg agccgggcac ggaggtcacg gcggcgatgc cgaccggacc
    11401 gcggggcccc tgggccctcc tcaagcggcg gcgccggcgg cggctgccgg ccgccgacgc
    11461 gacggccccg gcgacaccgg cccgggagac gtcggcgtga gctccgccgg gggcggccgc
    11521 ccccggcgcc cgcttcggcc ggacacgcca cgcccggctc ccgcccccgc gtccgccccg
    11581 gcatgcccct ccgcccctcg catgagcaag cgcttagaaa agtgcggccg gggtcacacc
    11641 tccacccccg tgacctcctt cgtacgtacg ggtaacttcc caatcagccc tgcccgtagg
    11701 tacacccgta cgccaatgga gccgtgatgc ccgaagccgt gatcgtctcg accgcccgct
    11761 cccccatcgg ccgcgctttc aagggctccc tcaaggacct gcgcccggac gacctgaccg
    11821 ccacgatcat ccaggccgcc ctcgccaagg tccccgagct ggaccccaag gacatcgacg
    11881 acctgatgct cggctgtggc ctccccggcg gtgagcaggg ccacaacctc ggccgcatcg
    11941 tcgccgtgca gatgggcatg gaccacctcc cgggctgcac catcacccgt tactgttcct
    12001 cctcgctcca gacgtcccgc atggccctgc acgccatcaa ggccggcgag ggcgacgtct
    12061 tcatctccgc gggcgtcgag gcggtgtccc gcagcgtcaa gggcaactcc gacagcctgc
    12121 ccgacaccca caaccccctc ttcgccgagg ccgaggcccg caccgccgcc gtcgccgaga
    12181 gcgcgggcgc gtcctggcac gacccgcgcg aggacggtct gatcccggac gcgtacatct
    12241 cgatgggcca gaccgccgag aacctcgccc gcatcaaggg cgtcacccgt caggacatgg
    12301 acgagttcgg cgtccgctcc cagaacctcg ccgaggaagc catcaagaac ggcttctggg
    12361 agcgcgagat cacgccggtc acgacccccg acggcacggt cgtcagcaag gacgacggcc
    12421 cgcgcgccgg cgtcaccctg gagggcgtgc agggcctcaa gccggtcttc cgccccgacg
    12481 gcctcgtcac ggccggcaac tgctgccccc tcaacgacgg cgccgccgcc ctcgtgatca
    12541 tgtcggacac gaaggcccgc gagctcggtc tcaccccgct cgcccgcatc gtctccaccg
    12601 gcgtcaccgg cctctccccg gagatcatgg gcctcggccc ggtcgaggcg tccaagcagg
    12661 cgctccggcg cgcgggcctg accatcgacg acatcgacct ggtcgagatc aacgaggcct
    12721 tcgccgccca ggtgatcccg tcctaccgcg acctcggcat cgacctggac aagctgaacg
    12781 tcaacggcgg cgcgatcgcc gtcggccacc ccttcggcat gaccggcgcc cgcatcaccg
    12841 gcacgctcat caattccctc cagttccacg acaagcagtt cggtctggag acgatgtgcg
    12901 tcggcggcgg ccagggcatg gcgatggtca tcgagcgcct cagctgagac cggctgcgcg
    12961 ccgccggccg aacccggccg cgtgacggga ggcggaccca gcgtgacctt caggcccgga
    13021 gcccgggaat cccaaggggt tccccccggc tccgggccgt tttgtgatcc aatctccccc
    13081 aggatgtgac ctatctccct ccaggagagg attcacgcag gtcagagcag tttcacgccg
    13141 atccccgggc cgaaagtcct gcccgtttcg tgacgttacg cactgacagc tgcttagtcc
    13201 gcccttcaag ctgatgtagg aagtcggggg gtcgactttg aaccgggagt acgtcagtga
    13261 gcgccatgcc gattgctctg ctgctcacca cagccgccac cgcggttgtg ggcgtcgccg
    13321 tcctgcgcac cctccagtcg ctgcgccggc agatagcggc tctgcacacc gaactgaccg
    13381 agagccgcgc cgcgagcgcg cgcggtctcg tgcccgccgc ccgctccacc gccgacgcgg
    13441 aggagatacg tgccgccgtg gccgaggcgc tcgccgagga gcgggagcgc gagctggccg
    13501 aggcacgggc gttctgggcc gcccaggagg cgcgtgacat ctccgacgcg ccgtccctgc
    13561 tgggcctgcc cgacagtgat ctgttcctgc cgcgccagtc ggacttcatg ggcctggagc
    13621 acgacagcct cgagccggtg gccgagccgg gtctggaggc cgacgagctc tccggggagt
    13681 cgcccgagct ggccgcggcc cgccgccgcc acccctcgca cccggacttc gtgccggtcc
    13741 agtcacccgt cgtgggcgac cacgagcgca cggtgacctg cctggaagag ctcgccgagt
    13801 cgcgtaccga actggccgac atccgccccg gcccgctggg caccctcgac gtctacgtct
    13861 tcgcggacgg tacgaccctg tgcatgaccc cgggccaccg ggacaccgcc gagcggctgt
    13921 ccgcggccct gcgcgccggc gacactccgg tactgctcgg cggctcgggc atctcggggg
    13981 cgtacgcgct gacgttcgcc tgcggcgagg agaccgtgta cgtcctggcg gaccgcgtca
    14041 tcgcgtcgct gtaaccgccg ccggagagcg gcctgcgcac cgcgtcggga gtcggatcag
    14101 accccggcgc gtttctgtgc ctcgaccacg agggtcaccg cctccgcgag ttcctcctcg
    14161 ttactcagta cgagtgccag atctcgtccg gcgacggtga tctggtccgc ggccgcgaac
    14221 atgcccgcgt cgggcatctc acggggctcg gcggcggggt cctccagccg ctgggcgcgc
    14281 agcgccaact ccctggccag ccccagtgct tcggccgcag cacttcgctg gagccggctc
    14341 tgcggagcgg cccgcagcag gtcggcgaaa tgatccacgg cacgggtcag aggcgtcgta
    14401 tcaaccacgc cgcgagacta cgcgccgcag cgggactgtt gccaacacgc gaacgctcag
    14461 gcacggtgac ctgaaggacc ggcttacatc cccttgcgtc ccggaggcgc cgatgtccca
    14521 agtcttctcc gcggagaccc atcgcaacct gctcgcccgc atcccccatt gcaccggtcg
    14581 tgaagtgtcc gactggctgc gcaccgtcga cgaaggcccc gctctcttcc gtttcgagga
    14641 aaaggtcagc tggcttcgcg ccgagcacaa cctcgcgtac ggccacgcca aggcgatcat
    14701 tcacgagtac gacctgagga gggccgcgcg caaactgctc tgagcgcgca ccgccgaacg
    14761 aaccggcatc cgagcacccg cagcacgacg aagggcccgc gaaccggagt tcgcgggccc
    14821 ttcactgccg gggcggcggc gctagtcgtt actgctgaag atggcgacca gccgcagcat
    14881 ctcgacgtag atccacacca gggtcatggt caggccgaac gcggccagcc aggcctcctc
    14941 gcgcggcgcg ccgtacgcga tgccgtcctc gatctgcttg aagtcgaggg tgaggaagaa
    15001 cgcgccgagc aggatcgcga tgatgccgac gaccgcgccc agcgggccca tgctgcgcag
    15061 tccgccgtcg ggggcgaccc cgaagacgac cagcagcagg ttgaccgcca tgaccaggat
    15121 gaaggcgatg gcgatggcca tgccgatgcg cgcgtaccgc gcggtcacgc ggatccagcc
    15181 cgccttgtag acgagcaggg tcgcgccggc gaccgccatg gtgccgagca ccgcctggaa
    15241 gggcgcgccc gaccactggc tgttgaacat ctcgctgatg accccgagga agactccctc
    15301 gaaggcggcg taggcgagga tcagcgcggg cgaggccgtg cgcttgaagg actgcaccat
    15361 cgccaggacg aacgcgatga gcgcggcgcc gatcgccagc gcgtagctgg tgctcgtcac
    15421 cggcagcacg gcccaggcga ggatcgcgcc gaccgcgacc gtgccgagcg tcatcgccga
    15481 gcgcatgacg acgtcgtcca tcgtcatccg gccggtggag accggagcct gcggcggagc
    15541 gccgtactgc tggccctgct gggcgtacgg gttctgcgcg taggggttgc cgccctgctg
    15601 ggcgtacggg ttggcctgcg tgccgacagc gggtcccccg gccggcggcg cggtgttgaa
    15661 gcccgcgtag ccgttgtcgc ggctgaaccc ccgacgcgag aagaccgggt tactgctcct
    15721 catttcactc ctccatggcc acctggcgtg gccttggcct caagagtaat aggtaggcaa
    15781 aggattgacc ctactgctta agaaggatct ttcccctgtg ctgccacggt acgcgtgtgt
    15841 cccatgcccg gcgagcactg gtacgaagcc gtaacagggc gctcgaccgg tagtggtccg
    15901 gtgcccgttc ggcgcccggt cagtcatccg ccgacgaccg gccggcgacc ggccggcggc
    15961 cgagcgcccg ttcgggtcac tccaggggga accggtgtac ccctccgcga ggtcggcctc
    16021 ggcggcgcgg gaggacgtga tccgctccag gcgggccagc tggacgcgct cctcgaacgg
    16081 cgtggcggcc ggcgggcggt gcagcagggt cgtcatgtcg tacgagaacc gctcggcctg
    16141 ccagacgcgg cgcagacagg tcgcggagta cgcgtcgagg cgctcgcccg atcccgtctc
    16201 cttcaggtgc gtcagcgccc gcgcgaaggt cacgacgtcc ccgacggcga ggttgaggcc
    16261 cttggccccg gtcggcggca cgatgtgcgc cgcgtccccg gcgaggaaga gccggccgtg
    16321 ccgcatgggc tcgtggacgt agccgcgcat gggggtgacg gacttctggg tgatcggccc
    16381 gcgctccagc cgccaggcgt cgtccgtctc gaagcgccgc tccagctccg cccagatctc
    16441 gtcgtccgcc caggcctcgg cgtccgtgcc ctcgggcacc tggaggtaga gccgggagac
    16501 ggccggcgag cgcatgctga gcagggcgaa gccgcgttcg tggcgggcgt agacgagttc
    16561 gtcgtgggag ggggcgacat cggcgaggac gccgagccag ccgaagggat acgtacgttc
    16621 gaagacgcgc gacacctcgg cgggcacggc ctgccgggcg acgccccgga atccgtcgca
    16681 gcccacgacg tagtcgcact ccaggacgtc ctcgcgcccc tcgtgggtga acggcacgcg
    16741 cggccgctcc gtccctgccc cctccacggc gagcgcctcg gcgccgaaga gcagcggtcc
    16801 gccctcctcg agctggagcg cgatgaggtc cttgcacacc tcggtctgcg cgtacaccat
    16861 cacggcgcgg ccgccggcga gcgcggggaa gtcgacgcgg tgccgcctcc ggtcgaaccg
    16921 cagctcgatc ccgtcgtgcc gcagcccttc ccggtccatc cgctccccgg ccccggcggc
    16981 ccgcagcacg tcgacggtcc cctgctcgag gatcccggcg cgctggcgcc gctccacgta
    17041 cgcccggtcc cggctctcca gaaccaccga gtcgatcccg gcgttgcgca gcagccgggc
    17101 cagcagcagt ccggccggtc cggccccgat gatcccgacg gtggtacgca tcggcacgcc
    17161 ccttcgcgtt cgcccggccc cgtggtcgag tgacggagtt cgcatggtga actttccttc
    17221 accatgctgg gtgagtttcc gaccggaggg gcgagctgtc aatgcccgga acggcctgcg
    17281 ggcccggcgc cgttgtgtca tccgtaggtc aggctcagcg ccaggtagca ggcgaaggtg
    17341 gacaggacgt agtacgccgg ggacgccgcg ggccagcgcg gggtccgggt ccgccagaac
    17401 cgccagccgg cccgggccgg cagcagcagg ggcagcaggg ccagcggcgt cagcaaggcc
    17461 accggacggg cctgggtcat cagcagcagg accgacagca ccggcgcgat cagcgccacg
    17521 gccaccgtcc cgccgaggcc gagggcatcg acataactgc gttcgccggg ccgtgtccgc
    17581 cgggtgatct tcttggcgaa ctccatgtgg acggtgacca gcacggtgat cacgatggcc
    17641 aggactccct cgcggccggg gcccgaggac gtgtcgtgga ggtagcgggc gtagaggtag
    17701 acgtggagca gcaactgagc ggggaagctg aacaggaggc tcaggaacag ccggtctccc
    17761 ggtggccagc ccagaaggcg gtcgacggtc agaaagagcc cgcagtagcc gagttgggcc
    17821 gccaggaccg cgagggccgt ggggctgccg gcgttgagtg ccagcacgag caccgcgccg
    17881 gccgcgcaca gcaccagcag gtccttcatc cgcacggttc cggcggccag cggccgcttc
    17941 gggtggaacg cgcggtcgta cgccagatcg cggatgtcat ccacggcgcg catcagcagc
    18001 agggtgacgg tgagcgtgac ggcggctgtg aaggtgccgg ttccgggccg ccagggcggg
    18061 ctctgcggct gcacggccgc gaacagcccg gtgaccccgt acgcccacag gaacgcgaac
    18121 agcaccgacg gcagcggggg gtaactgccc gccacgaagc gggtccagcg tctcagcacc
    18181 gtccgtcctc cttcgtgtgc cagcgcaccg gcagttccca cacgccgcgc atgaacatct
    18241 ggtcgcgcca gcggagttcc gccggttcga ccgccagttc caggtggtcc aggcgctcca
    18301 ggaccgcggt cagaccctcc tggagctcca cccgggcgtg tgcggcaccc aggcacatgt
    18361 gccggccgtg gccgaagccg atgtgcgggt tgggcgcgcg gtccgggcgg aactcgtccg
    18421 cgtcggggaa gacaccgggg tcgcggttgg ccgcgtcggt gagcgggatg acgacctggc
    18481 ccgcgggcag gacccggccc gcgagttcga cgtcctcgag tgccacgtgc ggctggccgc
    18541 cggtaccggc gaaccacacc caccgcagca gttcctccac gacggccggc accgcggacg
    18601 cgtcgcgcct gagccggtcg gcgaggccgg gtgtgcccag tacctggagg acgcacatcg
    18661 cgagatggga ggcggtggtc tcgccgcccg ccatcatcag gccgaagccg aagacgacga
    18721 tctcctcgtc gctgagccgg gtctcccgcg gcgcggacag cagcgacgtc agcaggtcgt
    18781 ccccggggca cccggccgcg atcgcctcgc ggcgcgcggc cagttgtccg aagaagtagc
    18841 cgtacatgac ctcgtgggcg cgggctgcct cgtcggcgga gaagcgtccg gcggacatca
    18901 tcaccgtcac cgacggcagc agtcggtcca gatcggccac cggcacgccg agcatctcgc
    18961 agatcacccg gtacgggaac ggagtggtga actcggcgat caggtcgacc ggccggccgg
    19021 tgtccgcggc ctgaagggag tcgagcagtt ccgcggcgat ccgcgcgatg cggggccggt
    19081 cctcctcggc tctgcggtgc gtgaagcggg actggacccg gctgcgacgc cgggtgtgcg
    19141 tgggcgcgtc gctggtgacc agcgcgagcg caccggacct gcgggcgaac agggtgccgt
    19201 tggcccacgc ctcccggctg aaacggtcgt cggacagcac ggtcctgacg tcggcgtacc
    19261 gggtcaccag cagggcctcg cggccgttcg ccagccctac cggcaccaac ggctcgcccc
    19321 ggtagcggtc caggagcacg gggtccaggg ggatgccgga caggccgggg aagggaaagc
    19381 ggggcaggtc cgccgtgctg ggggcgtgcg ggtccgccgc gtggggggcg gaccggtccg
    19441 ccgtacgggg ggcgggggcg gccggtgcgt cgggcggacc gggggccgga gcaccggctg
    19501 ccgtgcccgg gtcggccggc agcggcagaa cgtccgtccc gccgccggcg cccgagaacg
    19561 ggcaccgtgc gctcgcgccg ctcatcgcag ccacccctcg gcgggctcca gcgcctggtc
    19621 cggcgccccg tgccagtact cgtgcaagga ctcgcaccgc ccgtccggcg cgaaccgcag
    19681 cgccagacag cccgccgcgt tgcggggcgt accggtggcg gggtcgtaca gcacgcacca
    19741 ccactccacg gcggcccgcc ggcccgacac gaggggttcc ccgaaccaca tcttcgcgtc
    19801 cttctgccgt gacagcgtcc cgcgccagtg ctcggccacg gccgcccggc cggtgtgcgg
    19861 ggcgccgtag gggccctggt ggtagacggc gtcgtcggtg aagagggcgg ctatcgcctc
    19921 cgcgtcgcgg gcacgccacc ccgcctccag cgaaccgatc caccgggcca cggtcatggt
    19981 gccctctgct tgcgagacgg tcacttccac tccttgtatg ccgacgggct tccggtggcc
    20041 caggacggat tgccggtgat ctccacgacc gcgccgaaca gggagacccc gaagctgttg
    20101 ttgatcatca ggacccggtc gccctcgacg acctggcggg tctcgacgag atggtgcagc
    20161 gcggcgagtt ggtcgctggt ggtcatgtgg ccgaggtgtc ggccgaagtc gagtacgccc
    20221 cgcgccgggt cgatccccag gggttcgagc acggcccgga tgtactcggg acccccggag
    20281 agcacgtggg tgacccgggt gatgtcggac gggcgcagcc ccgcgtcctc gatggcccgc
    20341 agcgcgatct cggtacggcc cgcgtccagc gacttcctgg cgagcgtggc ggcccccggg
    20401 ttgtcgtggg cgtagtcgag cacccgggcg accaggtcga tgcggccggt gcgggtccgg
    20461 ttcggcggga acagggggcc gcggggccgg ttcatctcct ccagctccgg cagcgacgcc
    20521 gagacgatcg acctgacccg ggcgaagcct ccgcggctgg acaggacgac cgcggtggcc
    20581 gcgtcgccga ggatggacgg ccgcttcatg cgcgcgcccg cctggtagcg ccagcggtcg
    20641 acgcgttcgg tgccgaagtt ctcggcggcg gtcacgagcg ccgccgctct cgccggatcg
    20701 gcgctgaggt agccgtgggc cagttccagg gcgcccaggg ccgcgttgca gccctgccgg
    20761 acctccatgg cgggcacctg ggtgcccacc gcgtgccgca gcacgtactg gtgcggcgtc
    20821 cacagctcgg ggccctgctc gtgcagcgag gcgtgcagca ccagcgcgat gtcggcggcc
    20881 gggtgcccgg agcgctccag cgcggtgcgg gcggccttca ccgccatctc gggcggggag
    20941 atgttcccgg cgacggcggc gccggtccag ccgccgttcc tgtgttccgc cgcctcgtac
    21001 cggccctcgg cgacggcgcg ctcggcggga tagggcctgg gcaggtagca gccgaggccg
    21061 gcgatgtgca ggttgtccac gcgcacgggc tacgcctccc cgcgcgcggc cgtggtgccg
    21121 tcatgaccgg gggccgtgcc gtccgggtcg ccacgtccgg gcgccgcact gtccgagtgg
    21181 tcccgtccgg aagccgtggc gtcgtcggcc ttacggtgcg cggcgtcgtc ggcatcgtct
    21241 gcgtcgtctg cgtcgcgccg cgcggcttcc gctgcctcgc actgggctgc ctcggccgcc
    21301 gtcagcgggc gtaccgtgcc cgcgtcgccg tcgatctcca cccaggcgcc gtccgggacg
    21361 gccgtcatgg cgtccgtgac cgcgaccact gtcggtaccc cgagcagccg tccgctgatc
    21421 gcggtgtgcg agaccagact gccgcgctcc accacgatcc ccctggccgc catcatcagc
    21481 gccagccagc cggggtcggt ctccttcgcg atcagtatcc ggtccacgca ctgctcgggc
    21541 ggcacccgcg tgtcccggac gaccagcgcc cggccacggg ccctgccgct gctggaggcg
    21601 atgccgcgca gtacgccgtc ccgcgccaga ccggcccggg gccgggtgtc gcggcgcgag
    21661 gccagcgcca ccggcaccgg caggccgccg gggacggtga agtaggcggg cgggtccggc
    21721 gtggccgcgc gggcgtcctg ccgcgcctcg cgccgccggg ccaccgcgcg cagatccgtc
    21781 tcgggcaggg tgccgtcgaa cgcgccgagt acctcctcgg cctggaggtg cacgatgtcg
    21841 gacgcccggt ccagcatgcc cgcctcgacc agccgttccg cgagccgcca catcacctca
    21901 cgggagacgc cgtacagctg actgcggcag aaccgggtgt cctcgcgggc cttgacactg
    21961 aatcgcagcg aggcgagcac accgctgagc acggcccgcc gcagcggatt cgggcaggcc
    22021 tcgcgcagcg cgtgccgggc ggcgcgccgg gcggcggcct cgtcggcctc gttcgccgcg
    22081 acggtgagcc cctgggtgat gaagggccgt agcgcgggca cgatctgcca cggttcctgg
    22141 cgaggggtgc gcacctccag cttgagatcg tgcagggccc ggtcgccata ggtccgcaga
    22201 tgcctgtcga actcctcggc gacggcttcg ccgtggaccg aggaggcgat ctcctcccac
    22261 acctcccgct cgggtcgctc cagcacggcg gtgcgcagcg ccgggtcggc ggcgacgcgt
    22321 tcggccaggg cgatggagga acgcaccgac gccagagtgc ggttgggccg gccgccgccc
    22381 agcaggcgcg gcagcagcgc cgacccctcc ggcgcccagc gcttgagcag ggagtcggcg
    22441 cacgtcagcg ccaccagggc gaagtaactg gacaccatgg tgatgcccca gcggtgttcg
    22501 gcctcggccc acatggtgcg gtagcgggcg acgagttcgt ccgcggtgca gtcctcgaag
    22561 gagggccact gcgccatcaa ctcgtcccac cagcgcagga actgccgcag tcggcggggt
    22621 tgggtgacgt aggcccagcc gaggcggggc gaggcccgca gcacctcccc ccacgcgcgg
    22681 cggcggtccc cctcgtccgg acgggcgtgg tcgggcggct gtgtgaagcc gagcgaacgc
    22741 tgccacatgg ggcggatgag ctcgaagccg gggatctggc cgtgcagcgc gaaccaggcg
    22801 tcgagccggt agtacacccg cccgtccagg tggccgatca tccggctcag gtggtgctgg
    22861 ttgcgccgca gggaccgctt cggtacgccg acgcgccggt agaagtcggc gaagccggtc
    22921 cggtagaaga cccgggcctg tgagtacgtc agcgcgctgg tgacaccggg gaaggactcg
    22981 gtgaggttgt ggttggtcca cggcacgggc ggcacggcct cgtcccccgg cgcggccccg
    23041 gcacccggca cggccccggc acccggcacg gcgccctcac cgggcacggg cccggtctgc
    23101 accacggacc cggtctgcac cacggacccg gtctgcacca cgggcctggc ctgcaccagg
    23161 tggatcgcac cgtcactggt gatggtgccc tcgatgtcct gggggccgcc gaacagttcc
    23221 tccgcgcggg cggccagcgc accgacgcgg cggacatccg cgtcggagag caccgccttc
    23281 cgggcgagcg gggcggggac cggcaggacg accgggccct cgtcggcgcg ggccgggtcg
    23341 agaccgacca tcacggactt cacggcgagc tcgccgcgga cggcaccgtc ggcgcggttc
    23401 acgaagaagt ggtcgatgtc ggccttctcc tgcacgatgc cctcaccgat gccgtgcgcg
    23461 gcggcgacga ccgcctgttg ggcaccgccg cggggatcac gggtgaacat cacgaacgac
    23521 cgcactcccg gcaccatccg ctgcaccccg accgcgacgc gtaccgcggt gacgtcgacg
    23581 ccgcgccgca cccggtagag caccgcctcg gggttgtagg cggaggacca gcagtccacg
    23641 acccggtcga ggacggcgtc cctgcggacg tagaggtagc tgtcggacag cccggcgaac
    23701 gggtcgtcgg cgccgtcctc tccgctgccg tccgcctgcg ccgccgtaca gccgcgtacg
    23761 gcgacgagcc cgtcgggtcc ggcgagttcg tcgaaggcgg cgaggatccg cccggccagt
    23821 tccgccggca cccgcacggc gcggacccgg tcccgcgcgg cgcgcgccca ggccatcagg
    23881 tcaccggcgc tcgcaccggt gccggggaag ccggcgggca cgggcaccga cgcggcgaac
    23941 gcctcggcgg tcaggacgaa gaaggcgggc acgggaaggc cggcgcggcg catcgtgtgc
    24001 tgccgggaga acttgtgccc cacctggacc ggatcggcca gcgcgtcggc cgcgggcccg
    24061 gccagatgtg tatcaacggg cccggccaga tgggtgtcaa gggaagcggg ggcccccgcg
    24121 tcagtggttc cgcggccggt cgagccggtc gaaggggggt ggtggaccgt atgcgccatg
    24181 gcctaccaca cccccggcag gagccgtgcc cggccgcccg cgtaaccggc gtatccgggc
    24241 acctcccaca gcacccgttc ctcgacccgg acccgccagg tgaccacggc gcacagggcg
    24301 agaaggaaca gcacactcag cgggttgagg aagaacgaca cgaacgcggc gttggccagc
    24361 agcatcccgg tgtaggccgg gtgccgcacg tgtcggtacg ggccgtgcgt gaccacggaa
    24421 tggtcggaat agcggaccac gtggtgggag tagaagcgcc ccagagtacg gatggcgacc
    24481 aggcgcagcg cgaccgcggc ggtgaacacc acgaccggca cgaccagcca cgccgaccac
    24541 ccctgccacg gcagcggcca gagcaccgcg gacattccgg tgccggcgcg ggcgagggcg
    24601 tacggcagca gggtgctgtt ctccgcggcg gactgggagg gatgccgcac ggtgatcctg
    24661 gcctcggcga gtacccacag cacgtacagg ccggcgaaca gggcgcccgc caactgcggc
    24721 gtggaggcgt ggtcggtgag cagcagaccg atcgcggtca cgaacacggc gcaggtcacg
    24781 ggcagcaggg cccgcagcgc gaggacgacg aggcgctggt tcatgccgcc gcctcccggt
    24841 cggcgcgaaa ggcacggtag ccgtcggggg acaggccctt gctgacgtag atcagggaac
    24901 cgacggtgac gccctcgccc tcacccgcga cgacctcgaa ggtgagtctg gccttgtcgt
    24961 cggacatacg cacctgccgc cagcgcagcg aaagcggtac cgaggcgggc aggtcgagcg
    25021 gcaggtcggc ggtgagccgc agccacagca tctgtacttc cggcggccag ccgcccaccc
    25081 ggtgcgacaa ccaggtggcg aactgccggc cggcctcgat gacggacttc acggagcgca
    25141 ggcccgccct gcggctcgcc agggtgtgcc aggaagccgg gaccagtacg ggcgcggtga
    25201 ccagtccgtc ggtcgcccgg ggttcaccga tcatcacgtt cgccgggcgg gtgcgatgca
    25261 ccagcgaggc ctgcgcgggg gcctcacgac gggcgccggc ggcggagggg cggaccggat
    25321 cgctgtcggg ggtcagtacg aaccagccgt ccgagacgac ggccggcccc tgcgtgacgc
    25381 gcagcgggcg gcggcccttc tcctccggcg ccgcgtacag cacgagctcg ggagacagtt
    25441 ccggcatcac ccggaagttc accacccact tggcgcgtaa gcccgggggc acgtcgatgc
    25501 ggtcacgcac ggcgttcgcc atcccgcaca ccagcagcat gccggggacg tggtccagcg
    25561 ggtggtcgaa gaagaagggg tccctccggt cgacggtcag ctccgtcagc cacgagtccc
    25621 cgccgggtga cggggccggc ggcggcagca ggcctacccg gcttccgttc ctctcttctt
    25681 ctcgcgtcgt ctctatgtgc gtggtcatcc gcattcctcg tttcctgcct cttctgctcg
    25741 gcgcgtgacg tggagcgtgc ggtcccggca gctcggggcg ggatccgcct gcctctcgaa
    25801 cgccccgtcc gatggccggc cgggggggag gaggaggcgg tcgccgaggg tggacggctt
    25861 ggttccgtac gtcagtcgga ccgttgtcgg cccggcgccg gcccagtgtc gacgaggccg
    25921 ctgacacgcc gctgatcact cccggagccc tcctcggaga cccgggcggc caggtcacgc
    25981 cctcgttccg cggatcagcg gcgtgtcagc ggcgggggcc acgatgcgac ccctgttctt
    26041 ccgacccacg ggccgggtgc ggtcgtcggc cgtgcccgga gccgggtgcg atcccggtgc
    26101 ccgtggcccg acgagaaagg cctgtgcggt gattctggtg acgggcgcga ccggcgtggt
    26161 gggccgccag gtggcacaca cactggcgcg gtccggccgg gtgcgccttc tggtccgcga
    26221 cccggcgcgg ctcacggtcg aagggcccgg cgtcgaggtc gccaccggag cgtacgagga
    26281 ccacgcgtcg ctgctgcggg cactgaaggg cgtcgaggcc gcgttcctgg tcaccgtcga
    26341 tccgggcggt caggaggacg ggcggttcct gcgggcggcg gtggcggccg acgtacggca
    26401 tgtggtgaag ctgtcctcgt acgcggccgg tgaggacgac gccgacgacc tgatcacgcg
    26461 gtggcagcgg aagtgcgagg agacgctgcg ctcctccggg ctcgactgga ccctgctgcg
    26521 accgcgcgcc ttcatgtcca acaccctgtc ctgggcggac tccatccgcc gggaaggcac
    26581 cgtgcgagcc ctgtaccccg gctcggagaa cgcctgcgtc gacccccgtg acatcgccga
    26641 ggtcgcggtg accgcgctga cctcacccgg ccacgagggc cgggtgtatc ccctcaccgg
    26701 ccccgaagcg gtctccgcgg agcaacagac gcggcacctg gcggcggtcc tcggccgccc
    26761 gctggtctgc cgcgaactga caccacagca ggctgccgcc cggtgggcgc ggcgctaccc
    26821 gcccaaggtg gtgcacgcac tcgtcctgag cgcacaacgc cagctgctgg gccgcaagac
    26881 gacgaccgac cccacgttcg cccgggtcac gggccaccca ccacgctcct accgacagtg
    26941 ggcgacggac cacaggaacg cgttcgcctg aatgcgggca tgctcatcga cagcggctgt
    27001 cgacagcggc tctgaagact ttcggttcgt tcgcggcgtc acgtacgcca taaaacgacc
    27061 gcagagacgg cgtgctcccg tggtgttccc gggccacaaa agaaattcgg cacctccccg
    27121 ccgttccagc aggtaggtgc cgtggcgcgg gaggtgcccg gaaccggact tgaaccggta
    27181 cgcccgcgag gggcagcgag gtttaagctc gccgtgtctg cattccacca tccgggcagg
    27241 ccatgggctc cgcatcgagg ttccgagcct atcgggacgc atcctccgaa cagcgggcgg
    27301 tggacccgat gttgtcttat tttattgacg tctgagggtg catcagcacc cggtacgggc
    27361 catccgcact tgccagtagc ctttcgggca actcggaccg gcgtatgcgg aatgacggaa
    27421 tttcaccgcc cgcacacgac cctggtaccg cccgaacgag cgaggcgcac agtcggcgca
    27481 cagaaagccg cgactgcgcc ccctcagggg cggctgtcat ccccaggtat gagacgcgcc
    27541 ctgccggtca gtcccgagtc gcccccggga accggaacag cggctgacta cagggctccg
    27601 atcgggcccc aggatggaac acgtccccat catcgccgtc ccgacaggag caccctcccg
    27661 tgaccagcac tcccctcgcc gaccggacca ccgcggtggc cgcccgcgcc acggaactgt
    27721 cgaaggtcta cggacagggc gagacccagg tggtcgccct ggaccgggtc accgccgact
    27781 tccggcaggc cgagttcacc gcgatcatgg gcccctccgg gtccggcaag tccacgctga
    27841 tgcactgcgt cgcgggcctc gacaccttca gcagcggctc cgtgcgcata ggcgacaccg
    27901 agctcggctc gctcaaggac aagcagctca cgaagctccg ccgggacaag atcggcttca
    27961 tcttccaggc gttcaacctg ctgcccacgc tgaccgccct ggagaacatc accctcccga
    28021 tggacatcgc gggccgcaag ccggacaagc agtggctcga caacgtcatc cagatggtgg
    28081 gcctgtcggg acggctgagc caccggcccg cccagctgtc gggcggccag cagcagcgcg
    28141 tcgccgtggc ccgcgcgctc gcgtccaagc ccgacatcat cttcggcgac gagccgaccg
    28201 gaaacctgga ctcgcgctcg ggcgcggagg tgctgggctt cctgcgcaac tccgtacggg
    28261 agctggggca gaccgtggtc atggtcacgc acgacccggt ggccgcggcc tacgccgacc
    28321 gggtcgtctt cctggcggac ggacgcatcg tggacgaggt gcacgggccg acggccgacg
    28381 cggtcctcga ccgcatgaag cagttcgacg ccaagggccg cacgagctga cgtcccctca
    28441 cccccaccgc ccgggactga gccgacgtcc cctcacccca tacctcctgg actgagaaaa
    28501 cccatgttcc gtaccgcctt gcgcaccgta ctcgcgcaca aggccaggct cgtcatgacc
    28561 gtgctcgccg tgatgctcgg cgtggcgttc gtctcgggca ccctggtctt caccaacacc
    28621 atctcggacg cctaccagaa gagctccgcc aagggcttcg accaggtcga cgtcgccatc
    28681 caggcggaga gccgccagga cgagggcgac acgatcgccg agcggcccaa gctcacccag
    28741 gcgctcctcg acaaggccgc cgaggtgccc ggcgccggct ccgccatcgg cgtcgtgaac
    28801 ggcttcaccg ccatcgccga ccaggacggc aagctcgtcg gcaacggctt ccagtcgcag
    28861 ggcgggaact actgggggac caaggacccc cgttaccccc tgaccgtcgg acacgccccc
    28921 cgcggcaaga acgagatcgc cctcgacgcg aggacggccg agcgcgccgg atacaaggtc
    28981 ggcgacaccg tacggctctc cgtcgacggc ccggtgctca ccccgaaggt caccggcatc
    29041 ttcaccaccg acgacggcaa cgtcgcggcc ggcggcagcc tcgccctctt cgacaccgcg
    29101 accgcccagc agctgttcca caaggccggc gagtacgacg agatcgatgt gaaggccgcc
    29161 tccgggacga gccagatcgc gctgcgcaac gcgctcgacg aggtcgtgcc gaaggacgtc
    29221 gcctccacca ccaccggcaa gcagctcgcc gacgaccagg cgacccagat cgcctccgcg
    29281 atgagcggca tgaagaccgg cctgctggtc ttcgcgggca tcgcgctctt cgtcggcacc
    29341 ttcatcatcg ccaacacctt caccatgctg gtcgcccagc gcaccaagga gctggcgctg
    29401 ctgcgcgccg tcggcgcctc ccgcaggcag gtcacccggt ccgtactgat cgaggcgttc
    29461 gtcgtcggcg cggtcgcggc cgtcaccggt ctggccgcgg gcatcggcat cggcgcgggc
    29521 atgcgctccc tgatgggcac cctgggcgcc accgtccccg acggcccgct ggtcatctcc
    29581 ccgggcacgg tcgccacggc gctgctcgtc ggcatcctca tcaccatgct ggccgcgtgg
    29641 ctgccgggcc ggcgcgccgc gaagatcccg ccggtcgccg cgatgagcag cgtgcacgcc
    29701 aaggccacca ccaagtccct ggtcctgcgc aacacgctcg gcgccctgtt ctccgccgcc
    29761 ggcatcgcgg tcgtcctcta cgccaccacc ctggacggct cggacgggca ggccccgatg
    29821 ggcctcgggg cggtgctgct catcatcggc gtcttcatcc tcacgccact gctgtcacgc
    29881 ccgctgatcg ccgcggccgc cccggtgctg cgtatcttcg gggtctccgg caagctcgcc
    29941 cgccagaact ccgtacgcaa cccgcggcgc accgccgcga ccgcctccgc gctgatgatc
    30001 ggcctcactc tgatcaccgg catgacggtg atggcgggca gcctgcagac gtcgatcgac
    30061 aagatggcgt cctccgcgat caaggcggac tacgtcgtct cgatggccaa cggcaactac
    30121 ctctccacgg acgtcgacaa gaagctctcc gcgacggacg gcgtcaccgc caccagcccg
    30181 ctgcgcaacg cgccctcgcg catcgacggc gagaccgagt acctgaccgg cgtcaacggc
    30241 cggtccatca acgacctgac cgatctcacg gtccaggacg gcgccttcaa ggtcggcggc
    30301 acgcaggtcg tcgtcgacga cgagaccgcc gcgtcccacc actggacggc cggttcgcgg
    30361 ttcacggcct cgttcgagga cggcaagaag cagcggctca cggtcaccgg ggtgtaccag
    30421 agcaccgaga tgatgcgcgg catcatgctg gacaacgcca cgctcacccc gcatctgacc
    30481 gacccgtccg acatgcaggt catggtcaag acgtcggccg gcgcgtccgg cccggtcaag
    30541 gaccggctgg agaaggcact cggcgacaac ccggccatca aggtccagga caagaaggac
    30601 atctccaacg acatcgcgca gatgttcacg ctgatgctga acatgctcta cggcctgctg
    30661 gcgatggcgg tgatcgtcgc cgtcctcggt gtcatcaaca ccctggccat gtcggtcttc
    30721 gaacgctcgc aggagatcgg catgctccgg gcgatcggcc tggaccgcaa gggcatcaag
    30781 cggatggtcc ggctggagtc cctggtcatc tcgctcttcg gcggtgtgct cggcatcggc
    30841 ctcggcgtgt tcttcggctg ggcggccggt gaactgctcg gcaccaagat ggcgacgtac
    30901 gaactggtcc tgccctgggg ccggatggcc ctcttcctcc tgctggccgc ggcggtcggc
    30961 gtcctggcgg ccctgtggcc ggcccgccgg gcggcccgcc tgaacatgct gacggccatc
    31021 aagtcggagt aaccgacagc cgtacatgag gcggggcccc gttccgatcc ctggaacggg
    31081 gccccatttc gcgctgtgct cagttccagg tacgtgcccg cagagggatc ccggaggcgc
    31141 ccgactccgg tgtcctgacc gccagcacct ggttgacgcc gatgcggttg tgctcgaagg
    31201 cgagggcgca ggcggccatg tacagccgcc agacacgggc ccggcccggg ctcgtcagcc
    31261 gtacgccccg cacccactgg gcctccaggt tggcgaccca gcgccgcagg gtgagggcgt
    31321 agtgctcacg cagggactcg acgtcacgga cctcgaaccc ggcccgctcc agctgggtga
    31381 ccgtgctgcc gatgggcgcg agctcaccgt ccgggaagac gtacgcgtcg atgaactcgt
    31441 cgacggagta cgtggattcg tcgagctgcg gccgccgggc gatctggtgg ttgaggagcc
    31501 gcccgtccgg cttgagcagg gcgtacagat cccgcgcgta gtccaggtac cgctcggcgc
    31561 cgacgtgctc ggccatgccg atggaggaga tcgcgtcgta cgggccgtcg gtcacgtccc
    31621 ggtagtcctg tacgcggatc tcgacccggt cggtcagccc ctcgtcggcg acgcgcttac
    31681 gggcgtacgc ggcctgctcc tgggagaggg tgatgccgac gacgctcacg ccgtgctcgc
    31741 gggcggcgtg gatggccatg gagccccagc cgcagccgac gtccaggagc cgctgaccgg
    31801 gggtcagacc gagcttgcgg gagacgagtt cgagcttgtc gcgctgggcg tcctcgagtg
    31861 tgccgtccgg ggtggcccag taggcgcagg agtacaccat ggacgggccg aggacgatct
    31921 cgtagaagtc gttgccgacg tcgtagtggt ggctgatggc gcgccggtcg ctgcgcttgg
    31981 tgtgcagatg gccgcgtctg cggacctcct cgcggggcgg ggcgggcggc agcgggggtc
    32041 cggccatccg caccaggccg ctgaccgcgg cgcgtacgtc cgggtcacgc agggcctcgg
    32101 tgagggtacg ggcgtcgtcg cggcgctccc agaggagccc ggcgatcagg tcgaggacgg
    32161 cgtagaggtc tccccgcacc gtcacgtcgc ccgcgaccca ggcccgggcc aggcccagct
    32221 cgccgggttt ccacaacagc cggcgcaggg cgcggcgatt gcgcacgacg agggtgggag
    32281 caccgggcgg gccggcctcc gaaccgtccc acgcgtgaat acgcagcggg agcggggctc
    32341 ccagcaactg gtcgagaagg ctcttcagcc gcagcgcggc gtctggcatg gcgcacacct
    32401 ccgtgacggt agatcccgga acgtccaaca ccacgtaaac accggcggaa gccgcgcgca
    32461 gtcccccttt cgcgttacga gtgagcaaaa tagatgtagc gaccatgctt ctttcgcctg
    32521 cgcgggaacg ccgaaggggc ctcccgcacc acggatggcg gaaggcccct tcgggctgtt
    32581 cggtgaccgg aggtcaggag gccttggcct tctcctcggt cttcggcgcg accgcggcgg
    32641 ccggagccgg cgccggcttg gcggcctcgt agaactcctc gcgcggggac tccagcgcgc
    32701 ccagcgccac gacctcacgc ttcaggaaca tctgcagcgt ccagtccgcg aagacccgga
    32761 tcttccggtt ccacgtcggc atcgccaggc cgtggtagcc gcggtgcatg taccacgcca
    32821 gccggccctt gagcttgatc ttcatcttgc ccatgacgat catcgcgacg cccttgtgga
    32881 ggccgagccc ggccaccgca cccttgttgg agtgcgcgta ctccttctgc gggaagcccc
    32941 gcataccgga gaccacgttg tcgccgagga ccctcgcctg acgcagcgcg tgctgcgcgt
    33001 tcggcgggca ccaggcgttc tcgacgccgg ccttgcgggc ggccatgtcc ggcacctgcg
    33061 cgttgtcgcc ggcggcccag atgtagtccg tgccctgcac ctggagggtg gtctgggtgt
    33121 ccacgtgacc gcgcgggccg agcggcaggc cgaagcggga caggaccggg ttcggcttga
    33181 cgccggccgt ccacacgatc gtgctggagt cgacctcgag gccgttcttc agcacgacgt
    33241 ggccgtcgac gcaggagtcc atcgaggtgg agaggtagat ctcgaccccg cggctctcca
    33301 ggtgctcctt gccgtactgg ccgagcttgg ggccgacctc ggggaggatc ttgtcggcgg
    33361 cgtcgacgag gatgaaccgc atgtcctcgc gcgacacgtt gttgtagtac ttggccgcgt
    33421 cgcgggccat gtcctcgacc tcgccgatgg tctcggcgcc ggcgaagcca ccgccgacga
    33481 agacgaaggt caacgccttg cggcggacct cctcatcggt cgtcgagtcg gccttgtcga
    33541 gctgctcgag gacgtggttg cgcaggccga tggcctcctc gatgcccttc atgccgatgc
    33601 cctgctcggc gaggccgggg atcgggaagg tgcgggagac cgcgcccatc gcgatgacga
    33661 ggtagtcgaa aggcagctcg tacgcctcac ccacgagagg ggcgatcgtg gcgaccttgc
    33721 ggtcctggtc gatggtggtg acccggccgg tgaggacctc cgccttcggc agcacgcgtc
    33781 gcagcgggac gacgacatgc cgaggggaga tgctgccggc ggcggtttcg gggaggaagg
    33841 gctggtaggt catgtacgac cgggggtcga cgaccgtgac ggtcgcctcg ccgtagcgca
    33901 tcttcttgag aatgcgccga gctgcgtaca ggcctacgta cccaccgcct actacgagga
    33961 tcctgggacg ctccgtggtg ctcatgccat cgagtatcca cccgccccag gggggtcgct
    34021 cgtgcgcccc ttcacaagct tgggtgagcc ctctgctaca ctgcgcggct cacgtgaccc
    34081 aggtcatgtc gatggagggg aaccaccgcg cggtgcggac cgttgtcaac accgcgtgag
    34141 ctgcactccg gtcgttcgaa cgggccgaac caccctccgc gcccacccgc cggaaacaca
    34201 cccgcaacgc tccgctgagc accctcccgc acctggtgag cccccctgaa gggggcaacc
    34261 caccgaatcg tcgcccagca ggcccgaaat ccttgtgaag aacttcacga agttttccgg
    34321 cggtgtgccg cggagggggt ccggaaggcc ctcagagcgt gctcatacgt tatccgaact
    34381 gctcaggaga gactaccggc gggtagcaaa gtgtccccca ggtcacgccc aaggcccccc
    34441 gaaacgcctc acgaacacct cgccggacac ctcacgaacg tctcgccgac gagcgcgcga
    34501 gcgtctcgcc gacggccgcg cgagcgcccc gccgccgacc tcgcgaacgc ctcgctgacg
    34561 gccgcgcgaa ctacgcgatg gaccaggcga ttccgtcgag gatgtcgtgc tcgctgacca
    34621 cgacctcccg cgccccgatc cgctccatga tcgagagcag tacgagggcg cccgcgccga
    34681 tgacgtcgac gcggcccggg tgcatggagg ggacggccgc gcgttcggcg tgggtggagg
    34741 ccagcagcca ctcggtgatc tcgcggacgc ggtcgtacgg gatccgggag tggtggatgg
    34801 cgaccgagtc gtactccggg aggttctgcg cgatcgccga gatcgtggtg acggagccgg
    34861 ccaggccgac cagcgtgtgc gcctcgtgca gcggcacggt ctgctccacc aggtccagcg
    34921 ccgcgtcgat gtcggcccgg atcgcctcga tccggtcggg cgacggcggg tcgactacct
    34981 ggccgtcgtg caccaggtga cgttcggtca tacggacgca gccgatgtcg acggagcgtg
    35041 cggcgcgcac atggtcgtcg ccgaccacga actccgtcga gccgccgccg atgtccacga
    35101 cgaggaaggg cttggcgagg tcgtcgcggc cggtcagctc cttggtcgcg ccggtgaagg
    35161 agaactcggc ctcctggtcg ccggtgatga cctcgggctc gacacccagg atgtcgatga
    35221 ccccgcgcac gaactcgtcg cggttctcgg cgtcgcggga ggcggaggtg gcgacgaagc
    35281 ggatcttctc cgcgccgtgc tccttgatga tcgcggcgta ctcccggcag gccgcgaagg
    35341 tccgctccag ggcctcgggc gcgagccgcc cggtccggtc gacgccctgg ccgagccgga
    35401 cgatggtcat ccgccggtcg aggtcgacga gttccccggt ctccgggtgg gcgtcggcga
    35461 cgaggagccg gatggagttc gtaccgcagt cgatggcggc gacgcgggtc atggcagttc
    35521 cttgaggtcg aggggtgagt tctcggctcc ggtcggcggc gatcggcccg tccggcgttc
    35581 aaggacgggc cgttcaggcc gaagcggggg cctgggggcg cggcccccgg ggacgggaac
    35641 ggacggtcac tcgtcggcgg ccggcaccac gcaggccccc ttgcgccacc actccggcag
    35701 catcgcgatc gcctcgtcgc ccagcgggtt cacacccggg cccgcggcca gggagtgggc
    35761 caccagcaca tgcaggcact tcacccggtc cggcatgccg cccgcgctcg ggaagccctc
    35821 caggacctcg atggagtcgc ggcgggcgat gtagtcctcg tgcgccgcgc ggtaggccgc
    35881 ggccagctcg gggtcggtcg ccagccggtc cgtcatctcc ttcatgacgc cgttggcctc
    35941 gagggtgccg atcgcggacg cggcccgcgg gcacgtcagg tagtacgtcg tcgggaacgg
    36001 cgtgccgtcg ggcagccgcg gcgccgtctc gacgacgtcc ggctgtccgc acgggcaccg
    36061 gtgcgcgatg gcgcgcagtc cgcgcggcgg gcgcccgagc tgctgcttga aggcctcgac
    36121 gtccgcgtcg gtcggctcgg tgcgcggagt ggtcggcggg ggcgtttcca tgcctgtacg
    36181 taagtctctt tctcgttctt cactggtcgg aggcgtcgga cttgtcgacc ccgtcccaga
    36241 cgttggcgta ccaggggcgg tcggccgcac cctgcgtcgt ccgcgccggc ttggccgcgg
    36301 ccgggtcgat cacgatgtag ccggtctcgc ccggcatcac atagtgcagc cgctgccgga
    36361 tctgctgctc ggcgtaggcg tcgtcctgcc agcgggcctt gaggtcacgc agctgttcga
    36421 cgcgctgccg ggcccgctcc tgctgccgct ggagatcggc gacctcggcg cgctgggaca
    36481 cgtactgcct tatcgggtac gcgagggcca cgatcagcga gcacagcacc agcgcgagca
    36541 gcgcggcccg gctggtcagc cgggagcggc gggcctgccg cttggtctgg gagcggtaga
    36601 cgcgggccgc cgtctgctcg ccgagcagcc gcagcctggt cgcggtggag aaccggtccc
    36661 ggtccttcac ggccatctcc cgcctcccct tcacacgcgc gtacgtcccc gcacacggta
    36721 cgggaccgag tacggggacg tacgtacgac gctgcccaag ggccttggcg gatcagccct
    36781 cgctgtgcct gatcagttcg ccgagcggaa ccgggggaac gccgagcggc cggcgtactc
    36841 ggcggcgtcg tcgaggatct cctcgatgcg cagcagctgg ttgtacttgg cgacacggtc
    36901 cgagcgggcc ggggcgccgg tcttgatctg accgcagttc acggcgacgg cgaggtcggc
    36961 gatggtgacg tcctcggtct cgccggagcg gtgggacatc atgcacttga agccgttgcg
    37021 ctgggccagc tcgacggcgt ccagggtctc ggtcagcgaa ccgatctggt tgaccttgac
    37081 gagcagggcg ttggcggagc cctcctcgat gccgcgggcc aggcgctccg ggttggtgac
    37141 gaagaggtcg tcgccgacga tctggacctt gtcgcccagc ttgtcggtga tgaccttcca
    37201 gccggcccag tcgtcctcgt acagcgggtc ctcgatggag acgagcgggt acgcggagac
    37261 gagctcctcg tagtactcgg tcatctcggc ggccgagcgg gacttgccct cgaactcgta
    37321 cttgccgtcc ttgtagaact cggacgcggc gacgtcgagc gcgagcgcga tctgctcgcc
    37381 cgggatgtaa ccggcctgct tgatggcctc gatgatgagg tcgagcgcgg cgcggttcga
    37441 ctccaggttc ggggcgaagc cgccctcgtc gccgaggccg gtggacaggc ccttggtctt
    37501 cagcaccttc ttgagggtgt ggtagacctc ggcgccccag cgcagggcct cggagaagga
    37561 ctccgcgccg atcggggcga tcatgaactc ctggatgtcc acgttggagt cggcgtgcga
    37621 gccgccgttc aggatgttca tcatcggaac gggcagcagg tgcgcgttcg ggccgcccag
    37681 gtagcggaag agcgggaggt cgctggcctc ggaggcggcg tgcgcgacgg cgagggagac
    37741 gccgaggatg gcgttggcgc cgagcgagcc cttgttgtcg gtggcgtcca ggtcgaacat
    37801 cgcctggtcg atcaggcgct gctcggtggc gtcgtagccg acgagctccg ggccgatctg
    37861 ctcgatgacg gcgaggacgg ccttctcgac acccttgccc tggtaacggt tggggtcacc
    37921 gtcgcggagc tcgatggcct cgaaggcacc ggtggaggcg ccggacggga cggcggcacg
    37981 acccgtgctg ccgtcgtcga ggccgacctc gacctcgacc gtggggttgc ctcgggagtc
    38041 caggatttcc cgggctacga cgacgtcgat ggacggcacg agcatctcct tctgggatgt
    38101 gacgcgagtt acgccgggcc ggaggcccgg ttgggcgcag acctgtggag gccccgcggg
    38161 atgagcctaa ccggctctga gggatcggcc agccggtcga ccacctcatg gacagaaccg
    38221 agagtaaatt gtttccgaac ggaacaaaag agccccggta tatccggtgc gaccgggaca
    38281 agaaaaagcc ccgccccggt gcgtacgggg gaagacgcac cggagcgggg ggcccgtggg
    38341 gacgggggcg gcccctcacg aggcctccac catggaggtc acgtatggga gcgcgctgtg
    38401 gttcaggtac gagcctgttg tcagctcagg tggagctgct ggcccgggta gatgaagtcg
    38461 gcgtcgtcga cgatgtcctt gttcagcttg aacagcttct gccagccgcc cgcgacgtgc
    38521 ttcttctcgg cgatggagct gagggtgtcg cccttgacga ccttgtactc gccgtcgccc
    38581 ttcttgacct tcttgccggt cggggtctcg acggtcttgg cggccggccg ctcgtccgaa
    38641 cgggaggcgc gctgctcggt cgactgggtg gtgctgctct tcggggtgct ctgctgcggg
    38701 gtgctcgggg ccggcgagcc ggcgttgttc gcggcgcccg aaagtccggt gccgcaggtc
    38761 ggccaggcgc ccttgccctg ggcggcgagg accttctcgc cgaccgagat ctgctcggac
    38821 ttggaggcct ggtcggcggt ggaggcgtag gccgtgccgc cgtacgcggc ccaggtggag
    38881 gccgagaact gaaggccgcc gtagtagccg tttccggtgt tgatggacca gttgccgccg
    38941 gcctcgcact gggcgacggc gtcccactcg gaggcggtgg cggcggaggc gttgccggcc
    39001 gccatgagcg gggcggcgac ggcggcaccg gtgacaccgg cgatggcgat cgcacgagtg
    39061 gccttggacg ggcggcggtg cttgcccttg ctggaaagca gcatgaagtg atcccctcac
    39121 cgacgcctac gaggtgagct gtcgggttcg ggccggttga gttgcccggc cgcgcgcctt
    39181 cctctgccga ttccggcgcg cgacttcacc cctagccgga ccagcctcaa gtgctgggcc
    39241 cggcgcctac cttgggtccc ccgctcctgc ctgcggcgct tacgcgacga ctgttcccgt
    39301 acggccgctg gcaggattcg gcgttgcgac cgtcggggcc cgctgtggcg agcgatcacg
    39361 accgtaagca gtcgatcgcc ggaatttcaa agacgatcag ggcttctgag actcatctct
    39421 cactctcacc aaaccgggac attagcggtg aaagacggtc cgaactaccg ctgcttttcg
    39481 cccggttcgg cagcaagtgc aaggctctga ccggggacga tgacgtccgg gtcggcgccg
    39541 acggtcttct cgttctcggt gtacagcgcg gaccatccgc ccctgagccc aagggagtcg
    39601 gcgatggccg acaggctgtc tccggggcgc acgacgtacg cgtcgtcggc cgcgtcggga
    39661 gccgcctcgc gggagccgtc ggagccgcgg gaggcatgcc ggccggtgga gtcgtcggcg
    39721 cggccgtcgg cggcactctc gtcggccgtg tcgccgcggt gccggccgga gctggtggac
    39781 tccgcctcgg agggggtcga agcgtcgccg ttctgccctg acttgtccga gtcgtcactc
    39841 ttcgccgcat ccgcggacga gctgtcggaa gtcgaagagc cggacggcgt ggcgtcggcc
    39901 ttggcggagc ccttggaatc cttggccgcg gacgaggagc cggacgaaga ggacgagtcg
    39961 gacaggccgg agctgatgcc ggaaccggag tcggagtcgg ccgtggatcc gctgccgagg
    40021 aggcccgtgt cgacgtcggc cgaaccggag tcctggctga ggccgacagc gatgccgcag
    40081 gtggaccagg gggagctgcc cttggcggcg aggaccttct cggcgacggc tatctgctgg
    40141 gagcggctgg cctggtcggc actgggggcg tagtcgagac cgccgtactt ctcccagttc
    40201 ccctgggaca actggagccc gccgtagtac ccgttgccgg tgtcggcgct ccaggagcct
    40261 ccgctctcgc actccgcgac ctggtcccac gtcgtaccgc tggccgcgct ggcgccggtg
    40321 gcgccgagca acgggatcgc gatggccgag ccggtcacgc cggccgcgac gaggagggcc
    40381 ggagcctgac gggggcgtcg gtgtcgaccg ttcccggaga gcatgcggtt gcctttcgcg
    40441 tgacagcagt gagctgcgcg acggttgtgg ccaagcgccg cgcttgatgc gtgaacgtat
    40501 ccgtactcga acgcttgtca caagttaatg ccgcgcagat cacgtgaaga tcacagagtt
    40561 gaacgaatgt cagttctctc gcgacagctc tctgtgttag tgcatgcggg tacctcaccg
    40621 cccagctggg gtgaactcca ccggaagcgt gcgcaatcca tgcatgacgc gctttcggtg
    40681 cagcccaaat cgaccgaatc caccgcgagt tgcagttcct ggagaggggc gagcggcgtc
    40741 tgcccacagt cgggcggcgg gtacaccgag gcagcagtga cgccgtgccc gtagccgagg
    40801 tgctggttgt cacgtcggga gagtcggcac ggtggcgggg tcggcacggc ggcggggtcg
    40861 gcacggcggc ggggtcggca cggtggcggg gtcggccgcc ggtacgcgcc gactccagcg
    40921 agaacgcggc tcccggtacc gtcaccccgt gaacgcccca catagcgaac ccgaactctt
    40981 cacctgggag ttcgccaccg acccctaccc tgcctacgcg tggctccgcg agcatgcgcc
    41041 cgtgcaccgc accacacttc ccagcggtgt cgaggcgtgg ctggtg
//
