LOCUS       NC_003155              29809 bp    DNA     linear   CON 12-JUL-2024
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893, complete sequence.
ACCESSION   NC_003155
VERSION     NC_003155.5
KEYWORDS    RefSeq.
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Ikeda,H., Kazuo,S.Y. and Omura,S.
  TITLE     Genome mining of the Streptomyces avermitilis genome and development
            of genome-minimized hosts for heterologous expression of
            biosynthetic gene clusters
  JOURNAL   J Ind Microbiol Biotechnol 41 (2), 233-250 (2014)
   PUBMED   23990133
REFERENCE   2
  AUTHORS   Ikeda,H., Ishikawa,J., Hanamoto,A., Shinose,M., Kikuchi,H.,
            Shiba,T., Sakaki,Y., Hattori,M. and Omura,S.
  TITLE     Complete genome sequence and comparative analysis of the industrial
            microorganism Streptomyces avermitilis
  JOURNAL   Nat Biotechnol 21 (5), 526-531 (2003)
   PUBMED   12692562
REFERENCE   3
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kikuchi,H., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Genome sequence of an industrial microorganism Streptomyces
            avermitilis: deducing the ability of producing secondary metabolites
  JOURNAL   Proc Natl Acad Sci U S A 98 (21), 12215-12220 (2001)
   PUBMED   11572948
REFERENCE   4  (bases 1 to 9025608)
  AUTHORS   Omura,S., Ikeda,H., Ishikawa,J., Hanamoto,A., Takahashi,C.,
            Shinose,M., Takahashi,Y., Horikawa,H., Nakazawa,H., Osonoe,T.,
            Kushida,N., Shiba,T., Sakaki,Y. and Hattori,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2002) Contact:S Omura Kitasato University,
            Kitasato Institute for Life Sciences; 1-15-1 Kitasato, Sagamihara,
            Kanagawa 228-8555, Japan URL
            :http://avermitilis.ls.kitasato-u.ac.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000009765.2-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:55:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,040
            CDSs (total)                      :: 7,942
            Genes (coding)                    :: 7,651
            CDSs (with protein)               :: 7,651
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 293
            CDSs (without protein)            :: 291
            Pseudo Genes (ambiguous residues) :: 0 of 293
            Pseudo Genes (frameshifted)       :: 128 of 293
            Pseudo Genes (incomplete)         :: 220 of 293
            Pseudo Genes (internal stop)      :: 25 of 293
            Pseudo Genes (multiple problems)  :: 77 of 293
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:08:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2995048
            Orig. end                         :: 3024857
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BA000030.4.
            On Mar 29, 2016 this sequence version replaced NC_003155.4.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..29809
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="19"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..29809
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29809
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15809](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15809)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(178..1614)
                     /db_xref="GeneID:41539543"
                     /locus_tag="SAVERM_RS12810"
                     /old_locus_tag="SAV_2456"
                     /old_locus_tag="SAVERM_2456"
     CDS             complement(178..1614)
                     /codon_start=1
                     /db_xref="GeneID:41539543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298471.1"
                     /locus_tag="SAVERM_RS12810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2456"
                     /old_locus_tag="SAVERM_2456"
                     /product="DUF4173 domain-containing protein"
                     /protein_id="WP_042492990.1"
                     /transl_table=11
                     /translation="MRTATLWAAFATGVLSMLFLGDGLAVNLLFVAIPAALAAHFAAQA
                     AGRRTRAWTLVWGVGGLALLAVPALRDADWPSFLAVVTAVALGSLALHGGRTWPAVLLG
                     PIGVFNSVFTGAVWGWRGLRERAGGGHGRVGPVLRALVVAAVLLVVFGALFAGADAAFA
                     DLLGDLVPDASVSGGPWHVLLFVLGVVWALAAAHTAAAPARWDRAEIPEGRERGRVEWA
                     LPLIVLAVLFAVFNAVQLAVLFGGYDAVLKKTGQTYAEYARQGFWQLLLVTLLTLLVIV
                     VALRWAPRDGSRDRTLVRGVLGTLCALALVVVASAVRRMDMYVEAYGLTRLRISVLSAE
                     LWLGLVIVLIMAAGVWGARWLPRAVAASAAAGVLVFGFVSPDGLIAERNVQRYEETGKF
                     DLDYARDLSADAVPALDELKEPLRSCALRAIARGLGEDGPWYATSWGQARARQILDDRP
                     VSPDADWSVCDRFDTDLMYR"
     misc_feature    1574..1589
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.02"
                     /tool="antismash"
     misc_feature    complement(2173..2185)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 23.08"
                     /tool="antismash"
     misc_feature    complement(2312..2329)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(2335..3240)
                     /db_xref="GeneID:41539544"
                     /locus_tag="SAVERM_RS12815"
                     /old_locus_tag="SAV_2457"
                     /old_locus_tag="SAVERM_2457"
     CDS             complement(2335..3240)
                     /EC_number="3.2.2.-"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973213.1"
                     /locus_tag="SAVERM_RS12815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2457"
                     /old_locus_tag="SAVERM_2457"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_010983894.1"
                     /transl_table=11
                     /translation="MTADSSYDGRLERALSGLRGLAVGDALGSQFFVPAHYPLLKRREL
                     PPGPWRWTDDTEMTCSVVAVLAAHHRIDQDALARSFAEHLDPDRGYGPAVARLLRQVGE
                     GGDWRELASALFKGLGSWGSGAAARIAPLGAWYADDPEQATHQAEISAYPTHQHREAVV
                     GTMAVAAAAALAADPTGPPSAEALLDGVIALVPKSAVGAGLRRARDMLDYGDAATVAAV
                     LGCGRRTTAHDTVPFALWSAARALSDYEQAFWTTARVGGDVDTTCAIVGGVVAAGKAGA
                     PPGEWVERTEKLPDWVPGVA"
     gene            complement(3253..3912)
                     /db_xref="GeneID:41539545"
                     /locus_tag="SAVERM_RS12820"
                     /old_locus_tag="SAV_2458"
                     /old_locus_tag="SAVERM_2458"
     CDS             complement(3253..3912)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /db_xref="GeneID:41539545"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973214.1"
                     /locus_tag="SAVERM_RS12820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2458"
                     /old_locus_tag="SAVERM_2458"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_010983895.1"
                     /transl_table=11
                     /translation="MARPRRIVLVRHGESAGNADDTVYEREPDHALPLTEVGWRQAEER
                     GKQLRELFGQEGVSVYVSPYRRTLETLRAFHLDPDLVRVREEPRLREQDWGNWQDRDDV
                     RLQKAYRDAYGHFFYRFAQGESGADVYDRVGGFLESLFRSFEAPDHPPNVLIVTHGLAM
                     RLFCMRWFHWSVAEFESLSNPGNAEMRMLVLGNDGKYSLDRPFERWRDPERYGATG"
     misc_feature    3996..4011
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.66"
                     /tool="antismash"
     gene            complement(4106..4711)
                     /db_xref="GeneID:41539546"
                     /locus_tag="SAVERM_RS12825"
                     /old_locus_tag="SAV_2459"
                     /old_locus_tag="SAVERM_2459"
     CDS             complement(4106..4711)
                     /codon_start=1
                     /db_xref="GeneID:41539546"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1258: Antibiotic biosynthesis monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385166.1"
                     /locus_tag="SAVERM_RS12825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2459"
                     /old_locus_tag="SAVERM_2459"
                     /product="YdbC family protein"
                     /protein_id="WP_010983896.1"
                     /transl_table=11
                     /translation="MLVKWIRCTVVDRRGFERGQRRWAGLLGEPGFRGQGGGWSRGRPG
                     VAHIFAFWESRAFYDSFMARSHDRLAATQSGTFKDSQVKLFDHRFDVKTGFEPRFTDAD
                     LVRVAHCRVHEERAEHFALMQEKVWNPAMAGSPGMTRGLFGEAPGHEFLILSMWQSAAE
                     HGKYRAERVERLALRAQTEADVAALAGDIVDLEPAWIV"
     misc_feature    complement(4727..4740)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            4868..5401
                     /db_xref="GeneID:41539547"
                     /locus_tag="SAVERM_RS12830"
                     /old_locus_tag="SAV_2460"
                     /old_locus_tag="SAVERM_2460"
     CDS             4868..5401
                     /codon_start=1
                     /db_xref="GeneID:41539547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298465.1"
                     /locus_tag="SAVERM_RS12830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2460"
                     /old_locus_tag="SAVERM_2460"
                     /product="TerD family protein"
                     /protein_id="WP_010983897.1"
                     /transl_table=11
                     /translation="MNGLNKGIRKVELAVKWDPSPPGDPATDLDIVAATFLAGDAYGKP
                     AYVVHFDSRSPDGTIYLNRDSKDGKGFGWDEVMTLELNRLDSRYARVVVGVVIQQRDAH
                     RTFVGVLNPGLRMREGYTVLAEDDFGGVLGSTAATVGEFVRDDSGEWTFHPGIHGYDSD
                     PATFARVMGGRQDS"
     gene            complement(5494..8388)
                     /db_xref="GeneID:41539548"
                     /locus_tag="SAVERM_RS12835"
                     /old_locus_tag="SAV_2461"
                     /old_locus_tag="SAVERM_2461"
     CDS             complement(5494..8388)
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030467.1"
                     /locus_tag="SAVERM_RS12835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2461"
                     /old_locus_tag="SAVERM_2461"
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="WP_010983898.1"
                     /transl_table=11
                     /translation="MTETASGPARGSRAKGTKAKGLRIERIHTTPGVHPYDEVEWARRD
                     VVMTNWRDGSVNFEQRGVEFPDFWSVNAVNIVTSKYFRGAVGTPQREVSLRQLIDRIVK
                     TYRKAGEDYKYFASPADAEIFEHELAYALLHQIFSFNSPVWFNVGTPQPQQVSACFILA
                     VDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADASA
                     GTIKSGGATRRAAKMVILDVDHPDIEDFIETKVKEEEKIRALRDAGFDMDLGGDDITSV
                     QYQNANNSVRVNDTFMKAVEEGGKFGLTSRMTGEVIEEVDAKSLFRKMAEAAWACADPG
                     IQYDDTINHWHTCPESGRINGSNPCSEYMHLDNTSCNLASLNLMKFLKDDGKGRQSFEV
                     ERFAKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSD
                     GGRALAGAITSLMTGTSYKRSAELAAVVGPYDGYARNAQPHQRVMKQHSDANGVAVRVD
                     DLDTPIWAAATEAWQDVLHLGEKNGFRNAQASVIAPTGTIGLAMSCDTTGLEPDLALVK
                     FKKLVGGGSMQIVNGTVPQALRRLGYQEEQIEAIVAHIAENGNVIDAPGLKHEHYEVFD
                     CAMGERSISAMGHVRMMAAIQPWISGALSKTVNLPETATVEDVEEVYFEAWKMGVKALA
                     IYRDNCKVGQPLSAKKKETEKAEVTAKTEATIREAVEKVVEYRPVRKRLPKGRPGITTS
                     FTVGGAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPLETYV
                     SKFTNMRFEPAGMTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAEERQRHLE
                     TGSYEPSDDVDMDVEGLAQSAPRAQELKAVATPKAEVAAAVPAPKQAHTSAELVEMQLG
                     IQADAPLCFSCGTKMQRAGSCYICEGCGSTSGCS"
     gene            complement(8538..9101)
                     /db_xref="GeneID:41539549"
                     /gene="nrdR"
                     /locus_tag="SAVERM_RS12840"
                     /old_locus_tag="SAV_2462"
                     /old_locus_tag="SAVERM_2462"
     CDS             complement(8538..9101)
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539549"
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298474.1"
                     /locus_tag="SAVERM_RS12840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2462"
                     /old_locus_tag="SAVERM_2462"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_010983899.1"
                     /transl_table=11
                     /translation="MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETCS
                     LMVVKRSGVTEPFSRTKVINGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAELTTHD
                     VGLAILGPLRELDLVAYLRFASVYRAFDSLEDFEAAIAELREEQRERPAVDDEDHEDAG
                     AERQGTDRGSGGTVEVPVPATVAD"
     misc_feature    complement(9209..9223)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.14"
                     /tool="antismash"
     misc_feature    9211..9225
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.9"
                     /tool="antismash"
     misc_feature    9242..9256
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 26.06"
                     /tool="antismash"
     misc_feature    9529..9544
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.92"
                     /tool="antismash"
     misc_feature    9534..9543
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     misc_feature    9536..9549
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.71"
                     /tool="antismash"
     misc_feature    9545..9560
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    complement(9546..9559)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.93"
                     /tool="antismash"
     misc_feature    9546..9559
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
     gene            9620..10399
                     /db_xref="GeneID:41539550"
                     /gene="lexA"
                     /locus_tag="SAVERM_RS12845"
                     /old_locus_tag="SAV_2463"
                     /old_locus_tag="SAVERM_2463"
     CDS             9620..10399
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539550"
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526308.1"
                     /locus_tag="SAVERM_RS12845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2463"
                     /old_locus_tag="SAVERM_2463"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_010983900.1"
                     /transl_table=11
                     /translation="MTTTADSATITAQDRSQGRLEPVHAMNEATSHEGPKRSLPGRPPG
                     IRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALERKGF
                     LRRDPHRPRAYEVRGSDQSSSVQPTDTAGKPAASYVPLVGRIAAGGPILAEESVEDVFP
                     LPRQLVGDGELFVLKVVGDSMIEAAICDGDWVTVRRQPVAENGDIVAAMLDGEATVKRF
                     KREDGHVWLLPHNSAYQPIPGDEATILGKVVAVLRRV"
     gene            complement(10562..12595)
                     /db_xref="GeneID:41539551"
                     /locus_tag="SAVERM_RS12850"
                     /old_locus_tag="SAV_2464"
                     /old_locus_tag="SAVERM_2464"
     CDS             complement(10562..12595)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139142.1"
                     /locus_tag="SAVERM_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2464"
                     /old_locus_tag="SAVERM_2464"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_010983901.1"
                     /transl_table=11
                     /translation="MTKPSLPELLHAAVTAVGGTERPGQVTMAEAVAEAIDDSSHLLVQ
                     AGTGTGKSLGYLVPALAHGERVIVATATLALQRQLVERDLPRTVDALHPLLRRRPEFAM
                     LKGRSNYLCLHRLHEGVPQDEEEGLFDQFEAAAPTSKLGQDLLRLRDWSDETETGDRDD
                     LTPGVSDRAWAQVSVSSRECLGATKCAYGAECFAEMSRERAKLAEVVVTNHALLAIDAI
                     EGAPVLPQHEVLIVDEAHELVSRVTGVATGELTPGQVNRAVRRAAKLVNEKAADQLQTA
                     AEGFERLMELALPGRLEEIPEDLGYALMALRDAARTVISAIGATRDKSVQDEDAVRKQA
                     LASVESVHDVAERITNGSEWDVVWYERHDRFGASLRVAPMSVSGLLREKLFADRSVVLT
                     SATLKLGGDFNGVGASLGLAPEGTQGDDLPQWKGVDVGSPFDYPKQGILYVAKHLSRPA
                     RDGDRADMLDELTELIQAAGGRTLGLFSSMRAAQLAAEELRSRIPEFPILLQGEETLGE
                     LIKNFAADPETCLFGTLSLWQGVDVPGPSCQLVVMDKIPFPRPDDPLMSARQKAVEDAG
                     GNGFMAVAATHAALLMAQGAGRLVRASGDRGVVAVLDQRLATARYGSYLKASLPDFWYT
                     TDRNQVRRSLTAIDEAAKKTEVTEVTEVAEVTEEAAKESEGA"
     gene            complement(12828..>13400)
                     /db_xref="GeneID:91294961"
                     /locus_tag="SAVERM_RS45540"
                     /pseudo=""
     CDS             complement(12828..>13400)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91294961"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034854.1"
                     /locus_tag="SAVERM_RS45540"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DDLLGRVEDWGPTVTPAGTFQLAPVRPERDLPLLGRWMNDPAVAA
                     FWKLAGDESVTEQHLRAQLGGDGRSVPCLGVLEGTPMSYWEIYRADLDSLARHYPARPH
                     DTGIHLLIGGVADRGRGLGSTLLRAVADLVLDRRPSCARVVAEPDLRNTSSVSAFLGAG
                     FRFSAEVDLPDKRAALMVRDRPLRDLL"
     gene            complement(14001..15809)
                     /db_xref="GeneID:41539552"
                     /locus_tag="SAVERM_RS12860"
                     /old_locus_tag="SAV_2466"
                     /old_locus_tag="SAVERM_2466"
     CDS             complement(14001..15809)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539552"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385158.1"
                     /locus_tag="SAVERM_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2466"
                     /old_locus_tag="SAVERM_2466"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_202497909.1"
                     /sec_met_domain="IucA_IucC (E-value: 4.8e-71, bitscore:
                     238.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGTTADPLDHPEAQTAAQAAAVENLLRCWVRENGLVAPDDGTLR
                     IPLLATGTALLVPVHHWSPTGWHRFGLPYLADAPQTAPPADAVTVVALLAREAAGSRRA
                     PRPAHSAVDHCAVDHSADLVGRVADSVRRTAVFIDDRRARPADEPDLFLAAEQALLLGH
                     PLHPTPKSREGLSEAEARLYSPELRGSFALHWLAVAPPVLATNSAWTERGRPVPAEQLT
                     ARLAGDGLPMPDGFAALPLHPWQIREIRHRPEAAALLDAGLIRDLGPHGPAWHPTSSVR
                     TVHRTGAPAMLKLSLGLRITNSRRENLRKELHRGVEVHRLLRSGLGEQWQAAHPGFDIV
                     RDPAWLAVDDQHGNAVPGLDVMIRHNPFAPTDDVSCVAGLVSPRPWPQPTEQPRPVMRS
                     RLAEIIIRLAGRTGRPRGAVATEWFLRYLEQVVRPVLWLDSEAGIALEAHQQNTLLLLD
                     PEGWPTGGRYRDNQGYYFRTSRRAELEARLPGIGEHSDTFVSDEVTDERFAYYLGINNV
                     LGLIGAFGSQHLAEEQLLLAAFRRFLADVATGPARLRTPLPTRLLDSPVLRCKANLLTR
                     LHGLDELVGPVDTQSVYVTIANPLHS"
     misc_feature    15862..15878
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.9"
                     /tool="antismash"
     gene            complement(16227..17681)
                     /db_xref="GeneID:41539553"
                     /locus_tag="SAVERM_RS12865"
                     /old_locus_tag="SAV_2467"
                     /old_locus_tag="SAVERM_2467"
     CDS             complement(16227..17681)
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (47-381). E-value: 1.9e-90.
                     Score: 295.2. Matches aSDomain:
                     nrpspksdomains_SAVERM_RS12865_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GeneID:41539553"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009303271.1"
                     /locus_tag="SAVERM_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2467"
                     /old_locus_tag="SAVERM_2467"
                     /product="diaminobutyrate--2-oxoglutarate transaminase
                     family protein"
                     /protein_id="WP_010983904.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.8e-86, bitscore:
                     288.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTKSAVASLKREAEGAHAAHEGILRRQSARESAARTYARALPI
                     VPVRARGLTIEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRKVLDSGAPLHVLDLATP
                     VKDAFTTELFRTLPAGLADRARVQFCGPAGTDAVEAAFKLVRTATGRSGLLAFTGAYHG
                     MTAGALEASGGATDGRVARLPYPQDYRCPFGIGGERGAELGARWTESLLDDVKSGVPLP
                     AGMILEPVQGEGGVIPAPDAWLRRMRAITADRSIPLIADEVQTGVGRTGRFWAVEHSGV
                     VPDVMVLSKAIGGSLPLAVVVYRDDLDVWQPGAHAGTFRGNQLAMAAGTATLAYVREHR
                     LAERAQTLGARMLDQLRSLATEFPCVGEVRGRGLMIGVELVRAEEDREAVSPGSGDFAS
                     LDTAGAGPRPAAPELAAAVQRECLRRGLIVELGGRHASVVRLLPPLTISDEQATAVLDR
                     LADAVEAVARGRAERSRGFQRSERAG"
     aSDomain        complement(16539..17540)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAVERM_RS12865_Aminotran_3.1"
                     /evalue="1.90E-90"
                     /label="SAVERM_RS12865_Aminotran_3.1"
                     /locus_tag="SAVERM_RS12865"
                     /protein_end="381"
                     /protein_start="47"
                     /score="295.2"
                     /tool="antismash"
                     /translation="VRARGLTIEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRKVLDS
                     GAPLHVLDLATPVKDAFTTELFRTLPAGLADRARVQFCGPAGTDAVEAAFKLVRTATGR
                     SGLLAFTGAYHGMTAGALEASGGATDGRVARLPYPQDYRCPFGIGGERGAELGARWTES
                     LLDDVKSGVPLPAGMILEPVQGEGGVIPAPDAWLRRMRAITADRSIPLIADEVQTGVGR
                     TGRFWAVEHSGVVPDVMVLSKAIGGSLPLAVVVYRDDLDVWQPGAHAGTFRGNQLAMAA
                     GTATLAYVREHRLAERAQTLGARMLDQLRSLATEFPCVGEVRGRGLMIGVELV"
     gene            18213..19445
                     /db_xref="GeneID:41539554"
                     /locus_tag="SAVERM_RS12870"
                     /old_locus_tag="SAV_2468"
                     /old_locus_tag="SAVERM_2468"
     CDS             18213..19445
                     /codon_start=1
                     /db_xref="GeneID:41539554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432247.1"
                     /locus_tag="SAVERM_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2468"
                     /old_locus_tag="SAVERM_2468"
                     /product="hypothetical protein"
                     /protein_id="WP_010983905.1"
                     /transl_table=11
                     /translation="MRPIRPLFAARRGRSARRRTSPVLGAVGLATALALTATACDSGDD
                     TKASSESSPSASSAGDDKIKIPDDIRDKLKERGIDIDKWKNGAWKNWNRDDWLREANEY
                     INPIIKGLWDPDRMRDADDPDKNKGVDDNDLTGDQGVTDPTPAPVNAKAVQAAYHDNAP
                     TAGKVFFDAPEGTMVCSATVVEDPAHPGKSNLVWTAGHCVHAGKKGGWYRNIAFAPAYN
                     NAGQTTAELQNATKQEIAPYGVWWGDWAQTSQQWIEKGGETGGDGASYDYAVIHVTPEK
                     GGDGKSLEETVGSALPVDFNAPAVPKVSSITATGYPAAAPYDGQTLYQCQDKPGRLSIA
                     KSDPTMYRIGCTMTGGSSGGGWVATGSDGKPALVSNTSIGPVTSGWLAGPRLGPVAKGV
                     YDSVSKKFAGQ"
     gene            19641..20834
                     /db_xref="GeneID:41539555"
                     /locus_tag="SAVERM_RS12875"
                     /old_locus_tag="SAV_2469"
                     /old_locus_tag="SAVERM_2469"
     CDS             19641..20834
                     /codon_start=1
                     /db_xref="GeneID:41539555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973225.1"
                     /locus_tag="SAVERM_RS12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2469"
                     /old_locus_tag="SAVERM_2469"
                     /product="hypothetical protein"
                     /protein_id="WP_010983906.1"
                     /transl_table=11
                     /translation="MRSVRPPFARRRGRNTVLAATVAALALTATACNGSDDKASDKPET
                     TTSQAAGQDKARMPGDIAARLKEHGVDVDKWKNGGWKNWDKDKWLSEAKDFVNPVIKGL
                     WKPERMKSAKDPDKTISAKDASADQGVSDPDPAPVDATAEKTPYHEHAAPVGKVFFDSP
                     EGSMVCSGTVIKDVNHPGKSNLIWTAGHCVHAGGSGGWYRNIAFVPAYNDLGKSAAALS
                     DATSSEVAPYGQWWADWASTSHQWISGGDETGGAGAPYDYAVLHVKPESGSKSLEETVG
                     AALDVDFSAPSAQDVSAMGAWGYPAAPPYDGQQMFKCLDEPGRLSLSPSLPTMYRIGCT
                     MTGGSSGGGWFRVVDGETKLVSNTSIGPSDNTWLAGPQLGKGAKALYDTMSEQYGGR"
     gene            complement(20900..22393)
                     /db_xref="GeneID:41539556"
                     /gene="hflX"
                     /locus_tag="SAVERM_RS12880"
                     /old_locus_tag="SAV_2470"
                     /old_locus_tag="SAVERM_2470"
     CDS             complement(20900..22393)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539556"
                     /gene="hflX"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072894.1"
                     /locus_tag="SAVERM_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2470"
                     /old_locus_tag="SAVERM_2470"
                     /product="GTPase HflX"
                     /protein_id="WP_010983907.1"
                     /transl_table=11
                     /translation="MTSSSSPSQDAQSFAHTYPEGLRADALMEEDVAWSQEIDGDRDGD
                     QFDRSERAALRRVAGLSTELEDVTEVEYRQLRLERVVLVGVWTSGTIQDSENSLAELAA
                     LAETAGALVLDGVVQRRDKPDAATYIGSGKANELRDIVLETGADTVICDGELSPGQLIH
                     LEDVVKVKVIDRTALILDIFAQHAKSREGKAQVALAQMQYMLPRLRGWGQSLSRQMGGG
                     KGGGLATRGPGETKIETDRRRIREKMAKMRREIADMKTGREIKRQERRRNKVPSVAIAG
                     YTNAGKSSLLNRLTGAGVLVENALFATLDPTVRRAETPSGRLYTLADTVGFVRHLPHHL
                     VEAFRSTMEEVGDSDLILHVVDGSHPVPEEQLAAVREVIRDVGATGVPEIVVINKADAA
                     DPLVLQRLMRNEKRSIAVSARTGQGIAELLALIDNELPRPSVEIEALVPYTHGKLVARA
                     HTEGEVISEEHTPEGTLLKARVHEELAADLAPYVPAPLA"
     gene            complement(22579..24048)
                     /db_xref="GeneID:41539557"
                     /locus_tag="SAVERM_RS12885"
                     /old_locus_tag="SAV_2471"
                     /old_locus_tag="SAVERM_2471"
     CDS             complement(22579..24048)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481498.1"
                     /locus_tag="SAVERM_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2471"
                     /old_locus_tag="SAVERM_2471"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_010983908.1"
                     /transl_table=11
                     /translation="MPHTPRPRTRRVTSAMLASAVSVCLIAASAPAPAVPLGIGDRLFP
                     HLGNPGYDVASYDLAFTYPGANNKPLTAVTTINAQAKGRLDRINLDFAHGIVRSVDVNG
                     EPASFTGAGEDLVVTPEAPVSRGTPMRITVRHTSDPVSAKGQDSGWVRTEDGLVMANQA
                     DAAHLVFPCNDHPSDKAIFTIHVTAPDGYTAVANGRPAGADREGRATTWTYRTEHPMAT
                     ELAQVSIGRSSVLHRTGPRGLPVRDVVPTKDRKRLEPWLAKTPGQIAWMERRVGPYPFE
                     TYGLLVAQAQTGFELETQTLSLFERELFTRSTNPKWYVESIMVHELSHQWFGDSVSPRT
                     WSDLWLNEGHATWYEALYAEETAHRPMEPRMKEAYEASDSWRATGGPPAAPKGPEPGQK
                     ISIFRPNVYDGAALALYALRQEIGRPVFERLERAWVALHQDGTASTADFEQLASALSGR
                     DLSRFFKAWLYGEKTPPMPGHPDWKSGQATK"
     gene            complement(24260..26422)
                     /db_xref="GeneID:41539558"
                     /locus_tag="SAVERM_RS12890"
                     /old_locus_tag="SAV_2472"
                     /old_locus_tag="SAVERM_2472"
     CDS             complement(24260..26422)
                     /codon_start=1
                     /db_xref="GeneID:41539558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432251.1"
                     /locus_tag="SAVERM_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2472"
                     /old_locus_tag="SAVERM_2472"
                     /product="HD domain-containing protein"
                     /protein_id="WP_010983909.1"
                     /transl_table=11
                     /translation="MSAEATNPATPGPVTPGAYRRKGRPRIDLRRLGRAALLGPAARDR
                     LPDAIGHVAEAHRAHHPDADLEPLRRAYVLAESSHRGQMRKSGEPYITHPLAVTLILAE
                     LGAETTTLTASLLHDTVEDTEVTLDQVRAEFGEEVCYLVDGVTKLEKVDYGAAAEPETF
                     RKMLVATGNDVRVMSIKLADRLHNMRTLGVMRKEKQERIAKVTRDVLIPLAERLGVQAL
                     KTELEDLVFAILHPEEYERTRELIVGNAANGGDPLTEIVENVRTVLREAGLQAEVLIRP
                     RHFVSVHRVSRKRGRMRGSDFGRLLVLVNEDADCYGVLGELHTCLTPVVSEFKDFIAVP
                     KFNLYQSLHTAVAREDGEVAEVLIRTHQMHKVAEAGVIALGNPYTPGADDPAEGERADP
                     TRPGWLSRLLDWQEAAPDTDTFWSTLREDLAQDKEITVFRPDGGALGLPEGASCVDAAY
                     AQYGEDAHACIGARVNGRLATLSTVLKDGDTVQLLMGQDPASEPSREWLEHAHTPAARI
                     AIQRWLAAHPSPSPSEEPADGPATDGFAERFAADPAAEGAARFAPEGPAARPAANAVVD
                     QPGASVRLAGCCTPVPPDEITGFAVRGGVVTVHRVECAGVARMKSVGRAEVGVRWGDTS
                     ECRVTLVAESFGRPHLLADLTEAIAVEGVAIVSATVEPPSRQRVRHTYTLQLPDAAHLP
                     ALMRAMRNVPGVFDVSRAQHQAAAAQ"
     misc_feature    complement(26561..26576)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    complement(26568..26583)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.88"
                     /tool="antismash"
     misc_feature    complement(26598..26609)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.09"
                     /tool="antismash"
     gene            complement(26721..27590)
                     /db_xref="GeneID:41539559"
                     /gene="dapF"
                     /locus_tag="SAVERM_RS12895"
                     /old_locus_tag="SAV_2473"
                     /old_locus_tag="SAVERM_2473"
     CDS             complement(26721..27590)
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539559"
                     /gene="dapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000275.1"
                     /locus_tag="SAVERM_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2473"
                     /old_locus_tag="SAVERM_2473"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_010983910.1"
                     /transl_table=11
                     /translation="MSTRIAFLKGHGTENDFVIVPDPENAIDLPPAAVAALCDRRAGIG
                     GDGVLHVVRSAAHPEAREMAAEAEWFMDYRNGDGSVAEMCGNGVRVFARYLQRAGHVTE
                     GDLAVATRGGVKTVHIAKDGDVTVGMGKAFLPEGDVTVSVGERSWPARNVNMGNPHAVA
                     FVDDLAHAGDLLAPPPFSPPTAYPDGVNVEFVIDRAPGHVAMRVHERGSGETRSCGTGA
                     CAVAVAAARRDGADPAVTGTPATYTVDLPGGTLVITERPDGEIEMTGPAVIVAEGEIDA
                     EWLENAAL"
     gene            complement(27914..28441)
                     /db_xref="GeneID:41539560"
                     /locus_tag="SAVERM_RS12900"
                     /old_locus_tag="SAV_2474"
                     /old_locus_tag="SAVERM_2474"
     CDS             complement(27914..28441)
                     /codon_start=1
                     /db_xref="GeneID:41539560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072890.1"
                     /locus_tag="SAVERM_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2474"
                     /old_locus_tag="SAVERM_2474"
                     /product="hypothetical protein"
                     /protein_id="WP_037650098.1"
                     /transl_table=11
                     /translation="MEAGPRDTAQGAEQDTPERGDELGADGYRLEPDGVLLSPDGPDEQ
                     PPGGVTADGPEPEEMSPGPEVEVELRPQRRLRIWQLAPIVALAAVGSLMFAFPLAFEFG
                     DGGAVVAMLGLLICSCAAGWGMMAARRVGYTWPGLPQRGSGRRVDWRVVIAYAVVVAAV
                     VVLAVWRVARLR"
     gene            complement(28550..29488)
                     /db_xref="GeneID:41539561"
                     /gene="miaA"
                     /locus_tag="SAVERM_RS12905"
                     /old_locus_tag="SAV_2475"
                     /old_locus_tag="SAVERM_2475"
     CDS             complement(28550..29488)
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:41539561"
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034825.1"
                     /locus_tag="SAVERM_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAV_2475"
                     /old_locus_tag="SAVERM_2475"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_010983912.1"
                     /sec_met_domain="IPPT (E-value: 1.2e-81, bitscore: 272.8,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAPPAPRVIAVVGPTAAGKSDLGVFLAQRLDGEVVNADSMQLY
                     RGMDIGTAKLTPEERGGIPHHLLDIWDVTVAASVAEYQRLARARIDALLAEGRWPILVG
                     GSGLYVRGAVDNLEFPGTDPEVRARLEEELALRGPGALHARLAAADPEAGHAILSSNGR
                     RIVRALEVIEITGRPFTANLPGHDSVYDTVQIGVDVARPELDERIARRVDRMWEAGLVD
                     EVRALEAQGLREGRTASRALGYQQVLAALAGECTEDEARAETVRATKRFARRQDSWFRR
                     DPRVHWLSGAAADLTELPQLALMLVERPVTA"
     misc_feature    29654..29671
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
ORIGIN
        1 cggaggccgg gccacgtgga gctgagcggg ggccgtccga agcgatgggc aagggctgcc
       61 tgatcctcac cgccgccggc ctcggcgccc ctctcgccgt actcaccgct cgggagccgg
      121 caggtgcctc ggcaaccgct cggaggcggt cggcgccgat gaccgtgaga gcgcgcgtca
      181 gcggtacatc aggtccgtat cgaagcggtc gcacacgctc cagtccgcgt ccggcgagac
      241 cggacggtcg tcgaggatct gccgggcgcg cgcctgcccc cagctcgtcg cgtaccaggg
      301 gccgtcctca cccagacccc gtgcgatggc gcgcagcgcg caggaacgca gcggctcctt
      361 cagctcatcg agggccggta cggcgtcggc ggacaggtcg cgcgcgtagt cgaggtcgaa
      421 cttgccggtc tcctcgtacc tttggacgtt gcgctcggcg atcagaccgt ccggtgagac
      481 gaacccgaac acgagcaccc ccgcggccgc actcgccgcg acggcacgcg gcagccagcg
      541 ggctccccac accccggccg ccatgatgag cacgatgacc aggccgagcc acagctcggc
      601 cgaaagcacc gagatcctca gtcgcgtgag cccatacgcc tccacataca tgtccatacg
      661 ccgcacagcg gatgccacga caacgagcgc gagcgcgcac agagttccca gcacaccacg
      721 tacgagcgtc cggtcgcgcg atccgtcgcg cggcgcccag cgcagggcca cgacgatgac
      781 gagcagcgtc agcagcgtga ccaggagcag ctgccagaag ccctggcgcg cgtactcggc
      841 gtacgtctgg cccgtcttct tcagtacggc gtcgtacccg ccgaagagca cggcgagttg
      901 taccgcgttg aagaccgcga agagcacggc gagcacgatc agcggcagtg cccactcgac
      961 gcggccgcgc tcacggccct cgggtatctc ggcccggtcc cagcgtgcgg gagcggcggc
     1021 tgtgtgcgct gccgcgagcg cccagacgac gcccaggacg aacagcagga catgccaggg
     1081 gccgccggag acggaggcgt ccggcacgag gtcgccgagc aggtcggcga aggcggcgtc
     1141 cgcgccggcg aacagagccc cgaagaccac cagcagcacc gcggccacta cgagcgcacg
     1201 cagtaccggt cccacgcgcc cgtgcccgcc gcccgcacgc tcgcgcagtc cgcgccagcc
     1261 ccagacggcg ccggtgaaca cggagttgaa caccccgatc ggcccgagca gcacagcggg
     1321 ccacgtgcga cccccgtgca gcgcgagcga gccgagcgcg accgcggtga cgacggccag
     1381 gaaggacggc cagtccgcgt cgcgcagggc gggaaccgcc agcagcgcga ggccgcccac
     1441 tccccagacg agcgtccacg cgcgcgtgcg tcggcccgcc gcctgagcgg cgaagtgcgc
     1501 ggcgagggcg gccgggatcg cgacgaacag gaggttgacc gccagtccgt cgccgaggaa
     1561 caacatgctc aggacgccgg tggcgaacgc ggcccagagg gtggccgtac gcaccggagc
     1621 gggcggcccc gcctgaacgt cggcgagcca gggcgcgggc gatggcgacg gcgacggcgg
     1681 cgcccaatcg tcgtcctggt ccggttcggc ggaatcgtcg tcggccgagg agccgccctc
     1741 gtcgccggtg cgctcgaccg tcgcgacacc tccggaaacg gagcccgagc tcttgtcggc
     1801 gccagcggcg gcatctcggc tcgcacccgc cccggaagtc gcttccgcgc ggtcgcgctt
     1861 ctcacggccc tcggagcgct ctgagcgatc ggagtgctca gactgctcgg agcggctggc
     1921 acgcccggca ccgcgggatg cttcggaacc ttccggctgc gcatcccttg gctcgggcgt
     1981 ggacggtctg tcggacacgg gaccccctcc cagccggcct caccgcagcc ccaagaagac
     2041 cgcgggcgcg gcagagggct ggtgaccggt atctcgtcgg cacccgcccg tcatgatcat
     2101 caggcggcgt ggcggaaagg gtatccagac gcaccgcggc ccagaccgcg gcgatcactc
     2161 tgtggcaagg ctgtgacagt ggcacccgcc ctgcgccacg cccggccccc ggccctcaga
     2221 cccggcccag tgcccgaacc cagggaactc gccccaccac caccaccagc accagcacca
     2281 gcaccagcac cagcaccagc accagcacca gcaccagcac caggggatat ggccctacgc
     2341 cacccccggc acccagtccg gcagcttctc cgtacgttcc acccactccc ccggcggcgc
     2401 ccccgccttc cccgcggcga ccacccctcc gacgatggcg caggtcgtgt ccacgtcacc
     2461 gcccacccgg gcggtcgtcc agaaggcctg ttcgtagtcg ctcagcgccc gcgcggccga
     2521 ccagagcgcg aacggcacgg tgtcgtgcgc cgtcgtgcgc cgcccacagc ccagtacggc
     2581 cgcgacggtc gccgcgtcgc cgtagtcgag catgtcccga gcccgccgca gtcccgcgcc
     2641 gacggcgctc ttcggcacga gcgcgatcac tccgtcgagc agcgcctcgg cgctgggcgg
     2701 acccgtcgga tcggcggcca gggcggcggc cgcggcgacg gccatggtgc ccaccacggc
     2761 ttcacggtgc tgatgcgtgg ggtaggccga gatctccgcc tggtgggtgg cctgctccgg
     2821 gtcgtccgcg taccaggctc ccagcggcgc gatacgggcc gccgcgccac tgccccacga
     2881 tccgagcccc ttgaagaggg cggaggcgag ctcccgccag tcgccaccct cgccgacctg
     2941 acgcagcagc cgggcgaccg cgggcccgta gccccggtcg ggatcgaggt gctcggcgaa
     3001 ggagcgggcc agcgcgtcct ggtcgatgcg gtggtgcgcg gccagaactg ccaccacgga
     3061 gcaggtcatc tcggtgtcgt ccgtccaccg ccagggaccc ggcggcagct cgcggcgctt
     3121 gagcaggggg tagtgcgcgg gcacgaagaa ctgcgagccg agcgcgtccc ccaccgcaag
     3181 tccgcgcagg cctgacaggg cgcgctccag gcgcccgtcg tatgaggagt cagcggtcat
     3241 cgccttgcca ctctatccgg tggctccgta ccgttccgga tcacgccagc gttcgaacgg
     3301 ccggtcaagt gagtacttgc cgtcgttccc gagaacgagc atccgcatct ccgcgttccc
     3361 cgggttcgac agcgattcga actccgcgac cgaccaatgg aaccagcgca tgcagaacag
     3421 ccgcatggcc aggccgtggg tcacgatgag cacgttcggt ggatggtcgg gcgcctcgaa
     3481 gctccggaac agactctcca ggaaaccgcc gacccggtcg tacacgtcgg cgccggactc
     3541 gccctgcgcg aagcggtaga agaaatgtcc gtacgcgtcc cggtacgcct tctgcaggcg
     3601 tacgtcgtcg cggtcctgcc agttgcccca gtcctgctcg cgcaggcggg gctcctcgcg
     3661 gacgcggacg aggtcggggt ccaggtggaa cgcgcggagc gtttcgagcg tacgccggta
     3721 cggggatacg taaacgctta cgccctcctg cccgaagagc tcgcgcagct gtttgcctct
     3781 ctcctccgcc tgccgccatc ccacctcggt gagcggcagt gcgtgatcgg gctcgcgttc
     3841 gtagacggtg tcatcggcat tgcccgctga ctcgccgtgc cggacaagga cgatgcgccg
     3901 tggtcgtgcc atgccaaaac cctagatcgg gcggcgccgg atcgagcacc cacatgggct
     3961 ccatacggcg taggtcacac gtacatgccc gtttgaatgc gattcatccc ctttgaagag
     4021 cgccgttcgc accccggaca ggccatccgt tcgcgccctc cgaagaggcc atcgtccacc
     4081 ccttcgaaga gggaccgtcc agatatcaaa ctatccaggc cggttccaga tcgacgatgt
     4141 cgcccgccag ggccgcgacg tcggcctccg tctgggccct gagcgcgagt cgctccaccc
     4201 gctcggcgcg gtacttcccg tgctcggcgg ccgactgcca catcgacagg atcaggaact
     4261 cgtgccccgg cgcctccccg aacagcccgc gggtcatccc gggcgagccc gccatcgcgg
     4321 ggttccagac cttctcctgc atgagtgcga agtgctcggc ccgctcctcg tggacccggc
     4381 aatgcgcgac acgcaccagg tcggcgtcgg tgaagcgggg ctcgaaaccg gtcttcacat
     4441 cgaaacggtg atcgaagagt ttgacttgtg aatccttgaa ggtgcccgac tgcgtggcgg
     4501 cgagacgatc atgggagcgc gccatgaagg agtcgtagaa ggcacggctt tcccagaagg
     4561 cgaagatgtg cgcgacaccg ggccgtcctc ggctccagcc tccgccctgc ccccggaaac
     4621 ccggctctcc gagcagcccc gcccaccttc gctgcccccg ctcgaaaccg cggcggtcca
     4681 ccacggtgca gcgaatccac ttgaccagca ccgcgccatc gtaaggccac ggagcgtggc
     4741 acaggtcacg ctccggcgga gtgcacccga gcgagcgccc ccgcgcgcgt ggcacgatgg
     4801 acaactgacc tgggctgcac agcagttcgg gccgagggag tacagggcga cggggagggg
     4861 atctctggtg aacggtctca acaaaggcat ccgcaaggtc gagctcgcgg tgaaatggga
     4921 ccccagtccg cccggcgatc cggccaccga tctcgacatc gtcgccgcga ccttcctggc
     4981 cggcgacgcg tatgggaaac cggcctacgt agtgcacttc gacagccgct cccccgacgg
     5041 cacgatctac ctcaaccggg acagcaagga cggcaagggc ttcggctggg acgaggtcat
     5101 gacgctggag ctgaaccggc tcgacagccg ctacgcgcgc gtggtggtcg gcgtcgtgat
     5161 ccagcagcgc gacgcgcacc ggacgttcgt cggcgtcctg aaccccggcc tgcgtatgcg
     5221 cgagggctac accgtgctgg ccgaggacga cttcggcggc gtcctggggt cgacggcggc
     5281 gaccgtcggt gagttcgtac gcgacgactc cggtgaatgg accttccacc cgggcatcca
     5341 cggctacgac tcggacccgg cgaccttcgc gcgcgtcatg ggcggccgtc aggactcctg
     5401 accgcggccc cgcgagcgat ccggcccgcg aagcacccgc caacgccgaa gggcggcacg
     5461 gcccaaggcc gtgccgccct tcggggcttc aggtcagctg caaccgctgg tcgagccgca
     5521 accctcgcag atgtagcagg agccggcccg ctgcatcttg gtaccgcagg agaagcacag
     5581 cggggcgtcc gcctggatgc ccagctgcat ctccaccagc tcggcgctgg tgtgggcctg
     5641 cttcggggcg ggcaccgccg ccgcgacctc ggccttgggg gtggcgacgg ccttcagctc
     5701 ctgcgcacgg ggcgcggact gggccaggcc ctcgacgtcc atgtcgacat cgtcggacgg
     5761 ctcgtaggaa cccgtctcca ggtgacgctg gcgctcctcg gcggagtgga tgccgagcgc
     5821 ggaccgcgtc tcgaagggca ggaagtcgag cgccagacga cggaagatgt agtcgacgat
     5881 cgactgcgcc atccggacgt ccgggtcgtc cgtcataccg gccggctcga agcgcatgtt
     5941 cgtgaacttc gagacgtacg tctccagcgg cacgccgtac tgcagaccca ccgagacggc
     6001 gatcgagaag gcgtccatca tgcccgcgag ggtggagccc tgcttcgaca tcttcaggaa
     6061 gacctcgccg agaccgtcgt ccgggtagga gttggcggtc atgtagccct cggcgccacc
     6121 gaccgtgaag gacgtcgtga tcccgggacg gcccttgggc aggcgcttgc ggaccgggcg
     6181 gtactcgacg accttctcga cggcctcacg gatcgtcgcc tcggtcttcg cggtcacctc
     6241 ggccttctcg gtctccttct tcttcgcgga gagcggttgg ccgaccttgc agttgtcgcg
     6301 gtagatcgcg agcgccttga cgcccatctt ccaggcctcg aagtagacct cttcgacgtc
     6361 ctcgacggtc gccgtctccg gcaggttgac cgtcttggag agcgcgccgg agatccaggg
     6421 ctgaatcgcg gccatcatgc ggacgtggcc catcgcggag atggagcgct cgcccatggc
     6481 gcagtcgaag acctcgtagt gctcgtgctt gagacccggg gcgtcgatca cattgccgtt
     6541 ctcggcgatg tgggcgacga tcgcctcgat ctgctcctcc tggtagccca ggcggcgcag
     6601 ggcctgcggg acggtgccgt tgacgatctg catcgaaccg ccgccgacca gcttcttgaa
     6661 cttgaccagc gcgaggtcgg gctcaagacc ggtggtgtcg caggacatcg cgagaccgat
     6721 ggttccggtg ggcgcgatga ccgaggcctg cgcgttgcgg aagccgttct tctcgccgag
     6781 gtgcagcacg tcctgccagg cctccgtggc ggcggcccag atcggcgtgt ccaggtcgtc
     6841 cacgcggacg gccacgccgt tggcgtcgga gtgctgcttc atgacgcgct ggtgcggctg
     6901 cgcgttacgg gcgtatccgt cgtacgggcc gacgaccgcg gcgagctcgg cggagcgctt
     6961 gtacgaggtg ccggtcatca gcgaggtgat ggcaccggcg agggcgcggc cgccgtcgga
     7021 gtcgtacgcg tggccggtcg ccatcagcag ggcgcccagg ttggcgtaac cgatgcccag
     7081 ctgacggaag gcgcgggtgt tctcgccgat cttctgggtc gggaagtccg cgaagcagat
     7141 ggagatgtcc atcgcggtga tgaccagctc gacgaccttg gcgaagcgct cgacctcgaa
     7201 ggactggcgg cccttgccgt cgtccttcag gaacttcatc aggttcagcg aggcgaggtt
     7261 gcaggacgtg ttgtccaggt gcatgtactc gctgcacggg ttcgagccgt tgatacggcc
     7321 ggactccggg cacgtgtgcc agtggttgat cgtgtcgtcg tactggatgc ccgggtcggc
     7381 gcaggcccag gcggcctcgg ccatcttgcg gaagagcgac ttggcgtcga cctcctcgat
     7441 gacctcgccg gtcatgcggg acgtcagacc gaacttgccg ccctcctcga ccgccttcat
     7501 gaacgtgtcg ttcacgcgga ccgagttgtt ggcgttctgg tactggacgg acgtgatgtc
     7561 gtcgccgccc aggtccatgt cgaagcccgc gtcacgcagg gcgcggatct tctcctcctc
     7621 cttgaccttg gtctcgatga agtcctcgat gtcggggtgg tcgacgtcga ggatgaccat
     7681 cttggccgcg cggcgcgtgg cgccgcccga cttgatcgtt cctgcggagg cgtcggcacc
     7741 gcgcatgaag gagacgggac ccgaggcgtt gccacccgag gagaggagct ccttggagga
     7801 gcggatacgg gagaggttca ggccggcgcc ggagccgccc ttgaagatca tgccctcttc
     7861 cttgtaccag tcgaggatcg actccatgga gtcgtcgacc gccaggatga agcaggcgga
     7921 gacctgctgg ggctgcggag tcccgacgtt gaaccagacg gggctgttga agctgaagat
     7981 ctggtgcagg agggcgtacg ccagctcgtg ctcgaagatc tcggcgtcgg cgggcgaggc
     8041 gaagtacttg tagtcctcgc cggccttccg gtacgtcttc acgatgcggt cgatgagctg
     8101 cctgaggctc acttcgcgct gcggggtgcc gacggcaccg cggaagtact tgctggtgac
     8161 gatgttgacc gcgttcaccg accagaagtc ggggaactcg acgccacgct gctcgaagtt
     8221 gaccgagccg tcgcgccagt tggtcatgac gacgtcacgg cgcgcccact cgacctcgtc
     8281 gtacgggtgc acgcccggag tcgtgtggat gcgctcgatg cgcagcccct tggccttggt
     8341 gcccttggcg cgggaacctc gtgccggacc gctcgccgtc tctgtcatgc cgcctccctg
     8401 taccgggcta aaacgccctg aagtgcctcg ttcttcccgt ggcacggtgt gtgtctgctt
     8461 gtcgcgcacg ccgttcgcgg ctgcgcgcaa cgggtctgtg gtcgcctccg atcagaccgg
     8521 cccggccggc ctgcccgtca gtcggcgacg gtggcgggaa cggggacttc gacagtccct
     8581 ccggacccgc ggtcggttcc ctggcgctcg gcgccagcgt cttcgtggtc ctcgtcgtcc
     8641 acggcggggc gctcccgctg ctcttccctg agttccgcga tcgcggcctc gaagtcctcc
     8701 agcgagtcga acgcccggta gacggacgcg aaccgcagat aggcgacgag gtcgagctcc
     8761 cgcaaggggc cgagtatggc cagccccacg tcatgggtgg tcagctcggc gcttccggtg
     8821 gcgcgcaccg cctcctcgac ccgctggccg agctgggcga gtgcgtcctc ggtgacaggc
     8881 cgcccctgac atgccttgcg cacgccgttg atgaccttgg tgcggctgaa gggctcggtg
     8941 actccggacc gcttcaccac catcagcgag cacgtctcca cggtcgtgaa acgacgggag
     9001 cagtcggggc actggcggcg cctgcggatc gacgtgccgt catcggtcgt acgactgtcg
     9061 acgacgcggc tgtccgggtg cctgcagaag gggcagtgca tggctccaac cctccttcac
     9121 agcacgactc atagacctcg tgaggcctca cgggcccctc gaagcagccc caagcatagg
     9181 cgatggccgg accttcggaa gaccggggga ccacaacttg tgggctgccg ccgcaatgca
     9241 accactagat gtggggcctg actcgtaaat ccacccacga cgcgcgtgtc gtgcgcgtat
     9301 gggcatgtgc cgcacggcca taccgctcca gcaggcacgg agatacggtg ggcggtgtgg
     9361 ggaaaggggg tcggttcccc cttgacaggg tgcgcgatgg cagactgggc gccgacccgc
     9421 gtcggcccac aaggccctca cttcggcgct gaagagtaca gcaataggca cttttgtccg
     9481 ccggatgcga catcagccat acacgcagac gcttgatcac gtcaggcaat ccgcgttttt
     9541 tcactcgaac gtgtgtttgg cgcaaccttt cgaaagcaac taccgttgtc cagcagggag
     9601 accatcgaga ggggccgacg tgaccaccac cgcagacagt gccaccatca ctgcccagga
     9661 ccgctcccag ggccgactcg agccggtgca tgcgatgaac gaagccacaa gccacgaggg
     9721 acccaagcgc tccctgccag gccgacctcc aggcattcgc gccgacagct cgggactgac
     9781 cgaccggcag cgccgggtga tcgaggtcat cagggactcg gtgcagcggc gcggctaccc
     9841 gccgtcgatg cgggagatcg gccaggcggt cgggctctcc agcacctctt cggtcgcaca
     9901 ccagctcatg gcactggaac gcaagggctt cctgcgccgc gacccgcacc gcccgcgcgc
     9961 atacgaggtg cgtggatcgg accagtcgtc ctccgtgcag cccacggaca cggcgggcaa
    10021 gccggccgcg tcgtacgtgc ccctcgtcgg ccgcatcgcc gccggtgggc ccatcctcgc
    10081 cgaggagtcg gtcgaggatg tcttcccgct cccgaggcag ctggtcggcg acggtgagct
    10141 gttcgtcctg aaggtcgtcg gcgactccat gatcgaggcc gccatctgcg acggggactg
    10201 ggtgacggtc cgccgccagc ccgtcgccga gaacggcgac atcgtggccg cgatgctgga
    10261 cggcgaggcc acggtgaagc gcttcaagcg cgaggacggc catgtgtggc tgctcccgca
    10321 caactccgcg taccagccga tccccggtga cgaggcgacg atcctcggca aggtggtggc
    10381 ggtgctgcgg cgggtgtgac ccccgcagtc ggcggcacac cacgcccctg accgggcccc
    10441 gggaccacct gcgccggttc cggggccctg tgccgtccgg accccggtcc aggagtccgc
    10501 ggcgccgcga tcagcctgtc ccgcggccga ggccgttggg ggcaggctga tcgtcttccg
    10561 gctaggcgcc ttccgactcc ttggccgcct cttccgttac ttccgccact tctgtcactt
    10621 ccgtcacttc cgtcttcttc gccgcctcgt cgatcgcggt cagtgatctg cggacctggt
    10681 tacggtcggt ggtgtaccag aagtcgggca gtgacgcctt cagatagctc ccgtagcgag
    10741 ccgtcgcgag ccgctggtcc agtacggcga cgacgccgcg gtcccccgag gcccgcacca
    10801 ggcggcccgc gccctgggcc atgagcaggg ccgcgtgtgt ggcggcgacg gccatgaagc
    10861 cgttgccccc ggcgtcctcc acggccttct ggcgggcgct catcagcggg tcgtcggggc
    10921 gcgggaaggg gatcttgtcc atgacgacca gctggcagct gggccccggg acgtcgactc
    10981 cctgccagag cgagagcgtg ccgaagaggc acgtctcggg gtcggccgcg aagttcttga
    11041 tcagctcgcc gagcgtctcc tcaccctgga gaaggatcgg gaactcgggg atccgggagc
    11101 gcagctcctc cgcggcgagc tgggccgccc gcatcgagga gaacagaccc agcgtgcggc
    11161 caccggctgc ctggatcagc tccgtgagct cgtccagcat gtccgcccgg tcgccgtcgc
    11221 gcgcggggcg cgacagatgc ttggcgacgt acaggatccc ctgcttcggg tagtcgaagg
    11281 gggagccgac gtcgacgccc ttccactgcg gaaggtcgtc gccctgcgtg ccctcggggg
    11341 cgagtcccag agatgccccc accccgttga agtcgccgcc cagcttcagc gtcgcggacg
    11401 tcaggacgac cgaacggtcc gcgaaaagct tctccctcag gagcccggac accgacatgg
    11461 gggcgacccg cagggacgcg ccgaagcggt cgtggcgctc gtaccagacg acgtcccact
    11521 cggagccgtt ggtgatccgc tccgcgacgt cgtgcacgct ctccaccgaa gccagcgcct
    11581 gcttgcgcac cgcgtcctcg tcctgcacgg acttgtcgcg ggtggcgccg atcgccgaga
    11641 tcaccgtacg ggcggcgtcg cgcagtgcca tcagggcgta cccgaggtcc tcggggatct
    11701 cctccaggcg tccgggcagg gccagctcca tcagccgctc gaagccctcg gcggcggtct
    11761 ggagctggtc ggcggccttc tcgttgacga gcttggcggc gcgccgcacc gcgcggttga
    11821 cctggccggg tgtgagctcg ccggtcgcga caccggtcac gcgggagacc agctcgtggg
    11881 cctcgtcgac gatcagcacc tcgtgctgcg ggaggaccgg cgcgccctcg atggcgtcga
    11941 tcgcgagcag cgcgtggttg gtgaccacga cctcggcgag cttggcgcgc tcgcgggaca
    12001 tctcggcgaa gcactcggcg ccgtacgcgc acttcgtcgc gcccagacac tcccgggagg
    12061 acacggacac ctgggcccag gcgcggtcgg acacccctgg cgtcaggtcg tcgcggtcgc
    12121 cggtctcggt ctcgtccgac cagtcgcgca gccgcagcag gtcctgcccc agcttgctgg
    12181 tgggcgcggc cgcctcgaac tggtcgaaga gaccctcctc ctcgtcctgc ggcacgccct
    12241 cgtggagtcg gtgcagacac aggtagttcg accggccctt gagcatggcg aactccgggc
    12301 ggcggcgcag cagcggatgc agcgcgtcga cggtgcgggg caggtcccgc tccacgagct
    12361 gccgctggag cgccagggtg gcggtcgcca cgatgacgcg ctccccgtgc gcgagcgccg
    12421 gcaccaggta gccgagcgac tttccggtgc cggtgccggc ctggaccagc agatgggagc
    12481 tgtcgtcgat cgcctccgcg acagcttcgg ccatggtcac ctggccaggg cgctccgtgc
    12541 cgcctacggc agtgacggca gcatgcagga gttcggggag tgagggcttt gtcatagcgc
    12601 gaccacccta cggggcggca ctgacaaccg ggtgcccaag gccggagcgc gggacgcgat
    12661 caagggccgt gaagggggtg ggaggcggta ctgcgcacgg ccgcgtacgg gcctcggagc
    12721 ggtcgcgccg gcgatcaagg aagcgatcac ggcggcgggc ggattcggca cggggctcct
    12781 cggctcggaa ccggaacagg gcgcgcggtg tactgagacg gatcgcgcta caggagatcg
    12841 cgcaggggcc ggtcccggac catgagggcc gctcgtttgt cgggcaggtc gacctcggcg
    12901 gagaaccgga agcccgcgcc caggaaggcg gacacggagg aggtgttgcg cagatcgggt
    12961 tcagcgacca cacgtgcgca ggaaggacgc cggtcgagta cgaggtcggc gacggctcgc
    13021 agcagtgtgg acccgaggcc gcgcccgcgg tcggcgacac cgccgatgag gaggtgaatt
    13081 ccggtgtcgt gggggcgggc cggatagtga cgggccaagg agtcgaggtc cgcgcggtag
    13141 atctcccagt agctcatcgg tgtgccctcc agtacgccga ggcaggggac gctgcgcccg
    13201 tcaccgccca actgggcgcg cagatgctgc tcggtcaccg actcgtcgcc cgccagcttc
    13261 cagaaggcgg cgacagcggg gtcgttcatc cagcgcccga ggagcggaag gtcgcgttcc
    13321 gggcggacgg gggcgagctg gaaggtgccc gcgggggtga cggtggggcc ccagtcctcg
    13381 acgcggccga gcaggtcgtc agcggcccgg gtgacggaga cggcttgcct gccggcgagg
    13441 gccttggtgt cgccgaggga aggcggggcg ggtgcgggtg cggtggcgaa cgtgaccgac
    13501 ggggcagacg tgaccgacgg ggcggagggg accctagagg cggaggggac cgtagaggcg
    13561 gcagcgaacg gggccgccgg atcaacggcg tcggagcaac cgtccgaatc cgccgaagca
    13621 gccgtggcgc cggcgcgggc cgggacggag ggagcggccg tcgccgtgcc ctgcgcctcg
    13681 ggccccgcgt ccttacgccc cgctggctct tccgcgcctc ctaccgcatc ttcctcgccg
    13741 cccgctgtcc cttcctcgcc tcgtactgca ccatccccgc cgcccgcagc ctcttcgccg
    13801 cccgccgcct cttccgcggc gaagagcgcg acgagttcgt cgggcagccg cagttccagc
    13861 gtgtcctcgc tgtcggcggc tgagcgggct gagacggcga tacgggcggg gtccgcagag
    13921 gtagcgggct cggcgtcggt gctcgcatcg gtgggaggca cggcgacgct cctctcagaa
    13981 gacggggtgg gtcatgttcc tcaggaatga aggggattgg cgatggtgac gtagacggac
    14041 tgggtgtcga ccgggccgac gagctcgtcg aggccgtgca accgggtcag caggttggcc
    14101 ttgcagcgca gcacgggtga gtcgagcagg cgggtcggca gcggtgtgcg cagccgggcg
    14161 gggccggtgg cgacatcggc gaggaagcgt cggaaggccg ccagcagcag ttgctcttcg
    14221 gcaaggtgct gggagccgaa cgccccgatg agcccgagca cgttgttgat gccgaggtag
    14281 tacgcgaagc gttcgtcggt gacctcgtcg gagacgaagg tgtcactgtg ctcgccgatg
    14341 ccgggcagcc gggcctcgag ttccgcgcgc cgggacgtac ggaagtagta cccctggttg
    14401 tcccggtagc ggccgcccgt gggccagcct tcggggtcca gcaggagcag ggtgttctgc
    14461 tggtgggcct ccagtgcgat gcccgcctcg ctgtcgagcc acagcacggg ccgtacgacc
    14521 tgctccagat accgcaggaa ccactcggtg gccacggcac cgcggggacg gcccgtgcgg
    14581 ccggcgagcc ggatgatgat ctcggcgagc cgcgagcgca tgacgggacg gggctgttcg
    14641 gtgggctggg gccaggggcg tggcgagacg agcccggcga cgcaggagac gtcgtcggtc
    14701 ggggcgaacg ggttgtggcg gatcatcacg tcgagcccgg ggaccgcgtt cccgtgctgg
    14761 tcgtcgacgg cgagccaggc cgggtcgcgg acgatgtcga agccggggtg cgctgcctgc
    14821 cactgctcgc cgaggccgct gcgcagcaga cggtggacct cgacgccccg gtgcagttcc
    14881 ttgcggaggt tctcccggcg ggagttggtg atgcgcaggc ccagcgacag cttcagcatg
    14941 gccggggcgc cggtgcggtg gacggtgcgg acggatgagg tggggtgcca cgcggggcca
    15001 tgggggccga gatcccggat cagtccggcg tcgagcagcg cggcggcctc gggacggtgc
    15061 cggatctcgc ggatctgcca ggggtgcagc ggcagcgcgg cgaacccgtc gggcatcggc
    15121 agtccgtcgc cggcgagccg tgcggtcagc tgctcggcgg gcacgggacg accgcgctcg
    15181 gtccacgccg agttcgtggc gagtaccggg ggcgcgacgg ccagccagtg cagggcgaag
    15241 gatccgcgca gctcgggtga gtagaggcgg gcttcggcct cggagaggcc ctcgcggctc
    15301 ttcggcgtgg ggtgcagcgg gtgtccgagc agcagcgcct gttcggcggc gaggaagagg
    15361 tcgggctcgt cggcggggcg ggcgcggcgg tcgtcgatga agacggcggt gcgacggacg
    15421 gagtcggcga cacggcccac caggtcggcg ctgtggtcga cggcgcagtg gtcgacggcg
    15481 ctgtgcgcgg ggcggggggc gcggcggctt ccggccgctt ccctggccag cagcgccacc
    15541 accgtcaccg cgtcggccgg cggggccgtc tgcggcgcgt ccgcgaggta cgggaggccg
    15601 aagcggtgcc agcccgtcgg ggaccagtgg tgaacgggga cgaggagggc ggtgcccgtg
    15661 gcgagcaggg ggatgcgcag ggtgccgtcg tcgggggcga cgaggccgtt ctcccgtacc
    15721 cagcagcgca gcaggttctc gacggcggcg gcctgggcgg cggtctgggc ttcgggatga
    15781 tccagcgggt cggcggtggt gccgcgcagc cgctcactct cccgagcccg tccaaccggc
    15841 ggggggaccg attcggacgc ctgcacaact ggggtgcgga cctccggtac gaatacgacc
    15901 tgggtcgctg gtgcgagcgg ggcctgggtc tcaggtgccg gcgcggcctg agcctccgat
    15961 gcgaacacgg cctgggggcc ctgaacggtc gggagctggg tgtcgtggcc tgctcgctcg
    16021 tgagtgcggg agccgccgtc ggatgtgggg gtggcgttca acagagttcc tcgtggggcg
    16081 ttatggggcg ttgtggggcg ttcgggctcg cacggggcga gccggggaca cgggtgatgg
    16141 ggggggcgct gcgggccgtc cgggtcgatg cggctggggc gggggagcca tccaccgatc
    16201 ccgcctcacg ctccggccgt acgcgactac ccggcccgct ccgagcgctg gaagcctcgg
    16261 ctccgttctg cccgcccgcg cgccaccgct tccaccgcgt ccgcgagtcg gtccagcacc
    16321 gcggtcgcct gttcgtcgct gatggtcagc gggggaagca gccggaccac gctcgcgtgc
    16381 cggccgccca gttcgacgat caggccacgc cgcagacact cccgctggac cgcggccgcc
    16441 agttcgggcg cggcgggacg cgggcccgcg ccggccgtgt ccagggacgc gaagtccccg
    16501 gaacccggac tcaccgcctc gcgatcctcc tcggcccgca ccagctcgac gccgatcatc
    16561 aatccccgac cgcgcacttc cccgacacac gggaactccg tcgcgagtga gcggagttgg
    16621 tcgagcatgc gcgcccccag ggtctgcgcg cgttcggcga ggcggtgctc gcggacgtac
    16681 gcgagcgtgg ccgtgcccgc ggccatggcg agctggttgc cgcggaacgt gcccgcgtgg
    16741 gcgcccggtt gccagacgtc gaggtcgtcc cggtacacga cgacagcgag gggcagactg
    16801 ccgccgattg ccttcgacag gaccatcacg tccggtacga caccgctgtg ttcgaccgcc
    16861 cagaaccttc cggtacggcc cactcccgtc tgcacctcgt ccgcgatcag cggaatggac
    16921 cggtccgcgg tgatcgcgcg catccggcgc agccaggcat ccggcgcggg aatcaccccg
    16981 ccctcgccct gcacgggttc gaggatcatc ccggcgggca gcggcacgcc cgacttgacg
    17041 tcgtcgagca gcgactcggt ccaacgggcg ccgagttcgg cgccacgttc gccgccgatg
    17101 ccgaagggac agcggtagtc ctgtggatag ggcaggcgcg ccacccgtcc gtcggtcgcg
    17161 cccccggatg cctcgagcgc ccccgcggtc atcccgtggt acgcgccggt gaaggcgagc
    17221 agtccgctgc gcccggtggc cgtacgcacc agcttgaacg cggcttcgac ggcgtccgtc
    17281 ccggccggcc cgcagaactg gacgcgcgcc cggtcggcga gcccggccgg cagcgtgcgg
    17341 aacagctcgg tggtgaacgc gtccttgacc ggggtggcca ggtccaggac gtgcagcgga
    17401 gccccggagt cgaggacctt ccggatcgcc tccaggacca ccgggtggtt gtgtcccaga
    17461 gccagtgtcc ccgcgcccga gagacagtcg aggtagcggc gcccgtcggc cccctcgatg
    17521 gtcagcccgc gcgcccggac cggcacgatc ggcagggcgc gcgcataggt gcgtgccgcg
    17581 gattcgcgcg ccgactgacg ccgcagaatc ccctcgtgcg ccgcgtgcgc tccctcggct
    17641 tcacgtttca gggacgccac cgcagacttg gtcacagcca cgacgacagt tcctcccgct
    17701 gttcagaggc gagttgaggg agggcactga acggacgcgc tgaacacagg cggcaggccc
    17761 cccgtacgta ccaacgagac ggctcgctcg gggaagcggg tgagccgaag atccttgccg
    17821 atggctgcag accttgccga tggctggcga ccttgccgag acccaagacc tcgccgatgg
    17881 ctggaggccc cgccgatgcc cgatggtcct cgcccgtgac cggagacccc atcatgatcg
    17941 aaggcccttg cccgtgaccg ccgttctccg ggtgatcatc tccgtgacgg aaccgttgcc
    18001 gccccgtcgg atgtccccca cagcgaccgc atagtgtgtg gtgccgtccg gcggagacgg
    18061 atgatcatcg ggctatcggt tctcgcgaca gcgatagcgg tcgcgtaccg agggggccga
    18121 atccgcgcat ccgcaccaaa ccgcggtacg cgaccgcgta tcgcggtcgc acccgcagta
    18181 cagatgtctc ttcaccaggg ggagttcaca ccatgcgacc gattcgcccg ctcttcgccg
    18241 ctcgccgagg gaggagcgca cgccgcagga cctctcccgt gctgggcgcc gtcggcctcg
    18301 ccacggcact cgcgctgacc gccaccgcct gcgactcggg cgacgacacc aaggcgagca
    18361 gcgagtcgtc cccgtccgcg tcctccgccg gcgacgacaa gatcaagatc ccggacgaca
    18421 tcagggacaa gctcaaagag cgcgggatcg acatagacaa gtggaagaac ggcgcctgga
    18481 agaactggaa cagggacgac tggctgcgcg aggccaacga gtacatcaac ccgatcatca
    18541 agggcctgtg ggacccggac cggatgcgtg acgccgacga cccggacaag aacaagggcg
    18601 tcgacgacaa cgacctcacc ggcgaccagg gcgtcacgga cccgactccg gcgccggtga
    18661 acgcgaaggc ggtgcaggcg gcgtaccacg acaacgcccc caccgcgggc aaggtcttct
    18721 tcgacgcgcc cgagggcacg atggtctgtt cggcgaccgt ggtcgaggac ccggcgcacc
    18781 cgggcaagtc caacctcgtg tggaccgcgg gccactgcgt gcacgccggc aagaagggcg
    18841 gctggtaccg caacatcgcg ttcgcgcccg cgtacaacaa cgccggccag acgaccgccg
    18901 agctgcagaa cgccacgaag caggagatag ctccgtacgg cgtctggtgg ggcgactggg
    18961 cgcagacctc gcagcagtgg atcgagaagg gcggcgagac gggcggcgac ggcgcgtcgt
    19021 acgactacgc cgtcatccat gtgacgccgg agaagggcgg cgacggcaag tccctggagg
    19081 agacggtcgg ttcggccctt ccggtggact tcaacgcccc cgccgtgccg aaggtgagca
    19141 gcatcacggc gaccggctac ccggccgcgg cgccgtacga cgggcagacg ctgtaccagt
    19201 gccaggacaa gccgggccgg ctgtccatcg ccaagtcgga cccgacgatg taccgcatcg
    19261 gctgcacgat gaccggcggt tcgtccggcg gcggctgggt ggcgacgggt tcggacggca
    19321 agcccgcgct cgtgtccaac acctcgatcg gcccggtgac ttcgggctgg ctggccggcc
    19381 cacggctcgg cccggtggcc aagggcgtgt acgactcggt cagcaagaag ttcgcgggtc
    19441 agtagcgcga gggtctgaca ggagtcggac ggacggacgg cggcggggtg gtgggtgaaa
    19501 accttcacca ccccgccgct gttcgccccc attcgcccgg gcatagtgga gtgtcgcggc
    19561 cgggcgggtt ccacggagag ccacgccgcc gcctgacaag cacatgacag cactgcgttt
    19621 tcaacggggg ttacacaagc atgcgttccg tacgtccgcc cttcgcgcgc cggcgcggga
    19681 ggaacaccgt cctcgccgcg accgtcgcgg ccctggcgct caccgccacc gcctgcaacg
    19741 gcagcgacga caaggcgagc gacaagcccg agaccaccac ctcgcaggcg gccggccagg
    19801 acaaggcccg gatgcccggc gacatcgccg cccggctcaa ggagcacggc gtcgatgtcg
    19861 acaagtggaa gaacggcggc tggaagaact gggacaagga caagtggctc agtgaggcca
    19921 aggacttcgt caatccggtg atcaaggggc tgtggaagcc cgagcggatg aagtccgcca
    19981 aggacccgga caagacgatc tcggcgaagg acgcgtccgc cgaccagggc gtcagcgacc
    20041 cggatccggc gcccgtcgac gccacggccg agaagacccc gtaccacgag cacgcggccc
    20101 cggtgggcaa ggtcttcttc gactcccccg agggctcgat ggtctgttcg ggcaccgtca
    20161 tcaaggacgt caaccacccg ggcaagtcca acctcatatg gaccgcgggc cactgcgtgc
    20221 acgcgggcgg cagcggcggc tggtaccgca acatcgcgtt cgtgccggcc tacaacgacc
    20281 tcggcaagtc cgcggcggca ctgagcgacg ccacgtcgtc cgaggtcgct ccgtacggcc
    20341 agtggtgggc ggactgggcc tcgacctcgc accagtggat ctccggcggc gacgagacgg
    20401 gcggcgcggg cgcgccctac gactacgcgg tactgcacgt gaagcccgag tccggctcca
    20461 agtccctgga ggagacggtc ggtgccgccc tcgacgtgga cttctccgcg ccctccgcgc
    20521 aggacgtcag cgcgatgggc gcgtggggct acccggccgc gccgccgtac gacggccagc
    20581 agatgttcaa gtgcctcgac gagcccggcc ggctctcgct ctccccgagt ctgccgacga
    20641 tgtaccgcat cggctgcacg atgaccggcg gttcgtccgg cggcggctgg ttccgggtcg
    20701 tcgacggcga gaccaagctc gtctcgaaca cctcgatcgg cccgtccgac aacacctggc
    20761 tggcgggtcc gcagctgggc aagggcgcca aggcgctgta cgacaccatg agcgagcagt
    20821 acggcggtcg gtgaccgctc ccgtacaagc ggtaggcccg ccccctgtgc gagggggcgg
    20881 gcctaccggc tgtgacaggt caggcgagcg gtgccggaac gtacggcgcg agatccgccg
    20941 ccagctcctc gtgcacccgc gccttgagca gcgtgccctc cggggtgtgc tcctcggaga
    21001 tcacctcgcc ctcggtgtgg gcgcgcgcca ccagcttgcc gtgcgtgtac ggcacgagcg
    21061 cctcgatctc gaccgacggc cgcggcagct cgttgtcgat gagcgcgagc agctcggcga
    21121 tgccctggcc ggtgcgggcc gagacggcga tggagcgctt ctcgttcctc atcagccgct
    21181 ggagcaccag cggatcggcc gcgtccgcct tgttgatcac gacgatctcg ggtacgccgg
    21241 tggcgccgac gtccctgatc acctcgcgca cggcggccag ctgctcctcc gggaccgggt
    21301 gcgaaccgtc caccacgtgc aggatcaggt cggagtcacc gacctcctcc atggtggagc
    21361 ggaaggcctc gaccaggtgg tgcggcaggt gccgtacaaa accgaccgtg tcggccagcg
    21421 tgtacagccg gccgctcggg gtctcggccc ggcgcacggt cgggtcgagg gtcgcgaaca
    21481 gcgcgttctc gacgagcacg cccgcgcccg tgaggcggtt gagcagcgag gacttgccgg
    21541 cgttggtgta accggcgatc gcgactgaag gaaccttgtt ccgacggcgc tcctggcgct
    21601 tgatctcgcg gcccgtcttc atgtccgcga tctcccggcg catcttcgcc atcttctcgc
    21661 ggatccgccg acggtccgtc tcgatcttgg tctcaccggg gccacgggtg gcgaggccgc
    21721 cgcccttgcc gccgcccatc tgacgggaca gcgactgacc ccagccgcgg agcctcggca
    21781 gcatgtactg catctgcgcg agcgcgacct gcgccttgcc ctctcgggac ttggcgtgct
    21841 gggcgaagat gtcgaggatc agggccgtac ggtcgatgac cttgaccttg acgacgtctt
    21901 cgaggtggat gagctggccg gggctgagct caccgtcaca gatgacggtg tcggcgccgg
    21961 tctccaggac gatgtcccgc agttcgttgg ccttgccgga gccgatgtac gtggccgcgt
    22021 ccggcttgtc gcggcgctgg acgacgccgt cgagcacgag cgcacccgcg gtttccgcga
    22081 gggcggccag ctcggcgagc gagttctccg agtcctgaat ggtccccgag gtccagacac
    22141 cgacgagcac gacgcgctcc aggcggagct gtcggtactc gacctcggtg acgtcctcga
    22201 gctcggtgga gaggccggcc acacggcgca gggccgcgcg ctcggagcgg tcgaactgat
    22261 cgccgtcccg gtctccgtcg atctcctggc tccaggcgac gtcctcttcc atcagggcat
    22321 cggcccgaag accctcgggg taagtgtgcg cgaagctctg cgcgtcctgg gaaggggaag
    22381 aagaggaggt cattggatcc ttacgtagct ggggacaccg atacggcggc ggacatgaac
    22441 cgtcaccact cacaacgcgt gagtgccccg ggagattccc gggaaccgtc ccgccggggc
    22501 tctgcgcgcc ccccaggggc ccggccgcgc cgccgacctg aagatggtcg cacggaacgg
    22561 cccgtctcgt caccgggttt atttcgtggc ctgcccggac ttccagtccg ggtgcccggg
    22621 catcggcggc gtcttctccc cgtacagcca cgccttgaag aacctgctca ggtcgcgccc
    22681 cgagagggcg gacgccagct gttcgaagtc ggcggtcgac gccgtgccgt cctggtggag
    22741 ggccacccag gcccgctcca gtcgttcgaa gaccggtcgg ccgatctcct ggcgcagcgc
    22801 gtacagcgcg agtgcggcgc cgtcgtagac gttggggcgg aagatgctga tcttctggcc
    22861 gggctcgggg cccttgggcg ctgcgggcgg cccgccggtg gcccgccagg agtcggatgc
    22921 ctcgtaggcc tccttcatgc gcggctccat gggccggtgc gccgtctcct ccgcgtacag
    22981 ggcctcgtac caggtggcgt gtccctcgtt gagccacagg tcggaccagg tgcgggggct
    23041 gacgctgtcg ccgaaccact ggtgcgacag ctcgtgcacc atgatcgact ccacgtacca
    23101 cttcgggttc gtggaccggg tgaacagctc tctctcgaag agcgagagtg tctgtgtctc
    23161 gagttcgaag ccggtctgcg cctgggccac gagcagcccg tacgtctcga acgggtacgg
    23221 gccgaccctg cgctccatcc aggcgatctg gccgggcgtc ttcgccagcc acggttccag
    23281 ccgcttgcgg tccttcgtgg gtacgacgtc acggacgggc agaccgcgcg gaccggtccg
    23341 gtggagcacc gaggagcggc cgatggacac ctgggcgagt tcggtggcca tggggtgctc
    23401 ggtgcggtac gtccaggtgg tcgccctgcc ctcccggtcg gccccggccg gccggccgtt
    23461 cgccacggcc gtgtacccgt cgggtgccgt cacgtggatg gtgaagatcg ccttgtcgga
    23521 ggggtggtcg ttgcagggga agacgaggtg ggccgcgtcg gcctggttgg ccatcacgag
    23581 gccgtcctcc gtccggaccc agccgctgtc ctggcccttg gcggacacgg gatcactggt
    23641 gtgccgcacg gtgatccgca tcggggtccc ccgggagacc ggcgcctcgg gggtgaccac
    23701 caggtcctcg cccgcaccgg tgaacgacgc gggctcgccg ttgacgtcga ccgaccgcac
    23761 gatgccgtgc gcgaagtcca ggttgatgcg gtccagccgg cccttcgcct gtgcgttgat
    23821 ggtggtgacg gcggtgagcg gcttgttgtt ggcgccggga taggtgaagg cgaggtcgta
    23881 cgaggcgacg tcgtatccgg ggtttccgag gtgcgggaag agccggtcgc cgatccccag
    23941 ggggaccgcc ggcgcggggg cgctcgcggc gatgaggcag acggagacgg cggaggcgag
    24001 catcgccgac gtgacgcgac gggttctggg gcggggggtg tgcggcatgg accacggcta
    24061 ccagcgcgcg ggggcccggc ggtgacgact cgcaccggtc ccactcgaac gggttcgtgg
    24121 cggccccggg tgagccgggt gccgccgccg ggttccgcgg gggctctggg gttcgtaggg
    24181 gctccgggtt ccgcgggggc tccgtgacag cgccggactg ccatcgggcg gctccggcgc
    24241 gcggccgccc ggcccggagc tactgcgcgg ccgccgcctg gtgctgcgcc cggctcacgt
    24301 cgaacacccc gggcacgttc cgcatcgcgc gcatgagggc cgggaggtgt gccgcgtcag
    24361 ggagttggag cgtgtacgtg tgccgtacgc gctggcggct cgggggctcc acggtcgcgg
    24421 agacgatcgc gacgccctcc acggcgatgg cctcggtgag gtcggcgaga aggtgggggc
    24481 gcccgaacga ctcggcgacg agcgtgaccc ggcattcgga ggtgtccccc cagcgcacac
    24541 cgacctccgc gcgccccacg ctcttcatgc gtgccactcc ggcgcactcg actcggtgga
    24601 cggtcaccac tcccccgcgc acggcgaatc cggtgatctc gtcgggcggt acgggcgtac
    24661 agcagccggc caggcggacc gaggctcccg gctggtcgac gacggcgttc gcggcggggc
    24721 gggcggcggg tccttcgggg gcgaagcggg cggcgccctc cgcggcgggg tcggcggcga
    24781 agcgttcggc gaagccgtcc gtggcggggc cgtcggcggg ctcctcgctc ggcgacggcg
    24841 acgggtgcgc ggccagccac cgctggatgg cgatccgcgc ggcaggcgtg tgcgcatgct
    24901 ccagccactc cctggagggc tcggacgcgg ggtcctggcc catcaggagc tgcacggtgt
    24961 cgccgtcctt caggaccgta ctcagcgtcg ccagacggcc gttgacacgc gcgccgatgc
    25021 aggcgtgggc gtcctcgccg tactgcgcgt acgcggcgtc cacacaactc gcgccctcgg
    25081 ggagacccaa cgcgcccccg tcggggcgga acacggtgat ctccttgtcc tgggcgaggt
    25141 cttcgcgcag cgtcgaccag aacgtgtcgg tgtccggggc ggcctcctgc cagtccagga
    25201 gccgggagag ccagccgggg cgggtcgggt cggcgcgctc gccctcggcg gggtcgtcgg
    25261 ccccgggggt gtacggattg ccgagcgcga tgacaccggc ctcggcgacc ttgtgcatct
    25321 ggtgggtgcg gatgaggact tcggcgacct cgccgtcctc gcgcgccacg gcggtgtgca
    25381 gcgactggta caggttgaac ttggggacgg cgatgaagtc cttgaactcg gagaccaccg
    25441 gcgtcagaca tgtgtggagt tcaccgagga cgccatagca gtcggcgtcc tcgttcacca
    25501 gcaccaggag gcggccgaag tcggagccgc gcatccggcc gcgcttgcgg gagacgcggt
    25561 gcacggagac gaagtgccgg ggccggatga ggacttcggc ctgcagtccg gcctcgcgca
    25621 ggacggtgcg cacgttttcg acgatctccg tgagcgggtc gccgccgttc gccgcgttgc
    25681 cgacgatgag ttctctggtg cgctcgtact cctcgggatg caggatcgcg aagacgaggt
    25741 cctcgagttc ggtcttcagc gcctggacgc cgagccgttc ggcgagcggg atgagcacgt
    25801 cccgggtgac cttggcgatg cgttcctgct tctccttgcg catcacgccc agggtgcgca
    25861 tgttgtgcag ccggtcggcg agtttgatcg acatcacgcg tacgtcgttg ccggtggcca
    25921 cgagcatctt gcggaacgtc tccggctcgg ccgcggcgcc gtagtcgacc ttttccagct
    25981 tggtgacgcc gtcgaccagg taacagacct cctcgccgaa ctcggctcgc acctgatcga
    26041 gcgtcacctc cgtgtcctcg acggtgtcgt ggagcagaga cgccgtcaag gtcgtggtct
    26101 ccgcgccgag ttcggcgagg atcagggtca cggcgagggg gtgcgtgatg tacggctcgc
    26161 cgctcttgcg catctggccg cggtgcgagg actcggcgag tacgtacgcg cggcgcaggg
    26221 gttcgaggtc ggcgtcgggg tggtgggcgc ggtgggcctc ggccacatga ccgatcgcgt
    26281 ccggcagccg gtcgcgggcc gcggggccga gcagcgcggc ccggcccaga cggcgcaggt
    26341 cgatcctggg gcggcccttc ctgcggtacg ccccgggcgt gacggggccg ggcgtggcag
    26401 ggttcgtggc ctccgcgctc atgggcacct ccggctgctt ggaccggtgg acggggtgcc
    26461 ccatggcgta cgcggcactg gggatggcga cattcccccg tccgggccgg tgcttgatgc
    26521 taccgagccc accacgcgcg tccgaccgcc tctcgccgag cgtgaaacgg atcacccatt
    26581 cgagcgaagg ttcagaggtt tacgatttcg agccacgccg aatgcggccg accgtggatt
    26641 cgaaccggct cgggctgcgg aggctgcgct tgacggcttc cacagctgcc gaaggccgca
    26701 atgtcttacg gcccggcgcc tcagagggcc gcgttttcca gccactccgc gtcgatctcg
    26761 ccctcggcga caatcaccgc ggggccggtc atctcgatct cgccgtccgg gcgctcggtg
    26821 atcaccagcg ttccgcccgg gagatcgacg gtgtacgtcg ccggggtacc cgtcaccgcg
    26881 gggtccgcgc cgtcgcggcg ggcggcggcg acggccacgg cgcacgcgcc cgtgccgcac
    26941 gaacgggtct cgcccgagcc ccgctcgtgg acgcgcatcg cgacgtggcc gggggcgcgg
    27001 tcgatcacga actcgacgtt caccccgtcc gggtaggcgg tcggcggact gaagggcggc
    27061 ggggcgagca ggtcgcccgc gtgcgcgagg tcgtcgacga aggcgaccgc gtgcgggttg
    27121 cccatgttca cattgcgcgc gggccagctg cgctcaccga cgctcaccgt gacgtcccct
    27181 tcggggagga acgccttgcc catgccgacg gtgacgtcgc cgtccttggc gatgtgcacg
    27241 gtcttcacgc cgccgcgcgt ggccaccgcg aggtcgcctt cggtcacatg tccggcccgc
    27301 tggaggtagc gcgcgaacac ccgcactccg ttgccgcaca tctcggcgac cgagccgtcg
    27361 ccgttgcggt agtccatgaa ccactccgcc tcggcggcca tctccctggc ctccggatgg
    27421 gcggcggagc gcacgacgtg cagcacgccg tcgccgccga tgcccgcgcg gcggtcgcac
    27481 agggcggcga cggcggccgg gggcaggtcg atggcgttct cggggtccgg gacgatcacg
    27541 aagtcgttct cagtgccgtg acccttgagg aaggcgatcc gcgtgctcat ccctcgatcg
    27601 taaagggtcg gtacgacatt ccggcgagcg gtcggacaga cggtccgatc ggcggccgtg
    27661 gggtgtcggt ggtgtcggcc cggcaggcgg atcggcacag ccatgggcag gcggccccgc
    27721 aggcgtatcg gagtagccat gggccgtcga tcccgtagac gcatcgggca gccgtgggca
    27781 tcaggtcgcc ccgtcggcga tcggagcagc cgggccgtcg gtctcgcggg cggatccgat
    27841 cacgcggcag gcgggtccgg cagacgaacc gggttgcccc tgagcagtcg ctccggtagg
    27901 tggatcgggc cgctcagcgc agccgcgcca cgcgccacac ggcgagcacg acgaccgcgg
    27961 cgacgacgac ggcgtacgcg atcacgaccc gccagtccac gcggcggccg gagccgcgct
    28021 gcggcaggcc cggccaggtg tagcccaccc ggcgggcggc catcatgccc cagccggcgg
    28081 cgcaggagca gatcagtagt ccgagcatgg cgaccacggc accgccgtcg ccgaactcga
    28141 aggccagcgg gaaggcgaac atcagcgagc cgaccgcggc cagcgccacg atgggcgcga
    28201 gctgccagat ccgcagccgg cgctggggac gcagctcgac ctcgacctcg ggtcccgggg
    28261 acatctcttc cggttccggt ccgtcggcgg tcacgcctcc cggcggctgc tcatcgggcc
    28321 cgtccgggct cagcaaaact ccgtcgggct ccagtcggta cccgtcggcg cccagctcgt
    28381 ccccgcgttc cggggtgtcc tgctccgcgc cttgtgcggt atcgcgaggg ccggcctcca
    28441 tcgccacgcg ccctcccaac tcggactcca cttggtcgat cgaagctcga tgatggcacg
    28501 ccgccggagg cgcggatgac ggccggagcg tcccgatgcc atgacgtgat caggctgtaa
    28561 ccggtcgttc gaccaacatc agtgcgagct gcggaagttc tgtgagatcc gccgcagccc
    28621 cactgagcca atgcacccgg gggtcgcgcc tgaaccatga atcctgacgg cgcgcgaagc
    28681 gcttggtggc acgtacggtc tcggcgcgcg cttcgtcctc ggtgcactcc ccggcgagcg
    28741 ccgcgagtac ctgctggtag ccgagcgcac gcgatgccgt acgcccctca cgcaacccct
    28801 gcgcctccag cgcgcgcacc tcgtcgacga ggcccgcctc ccacatccgg tcgacccggc
    28861 gtgcgatgcg ctcgtcgagt tcggggcgcg ccacgtcgac cccgatctgg acggtgtcgt
    28921 agacggagtc atggcccggc aggttggctg tgaagggccg gccggtgatc tcgatcacct
    28981 cgagggcccg gacgatgcgg cggccgttgc tggagaggat cgcgtggccg gcctcggggt
    29041 cggcggcggc caggcgggcg tgcagcgccc cggggccgcg cagcgcgagc tcctcctcga
    29101 gccgggcccg cacctcgggg tcggtgccgg ggaactccag gttgtcgacg gccccgcgca
    29161 cgtacagccc ggagccgccc accaggatcg gccagcgacc ctcggcgagc agggcgtcga
    29221 tgcgggcgcg ggccaggcgc tggtactcgg cgacgctggc ggcgacggtg acgtcccaga
    29281 tgtccaggag atggtgcggg atgccgccgc gctcctcggg cgtcagcttg gcggtgccga
    29341 tgtccatccc tcggtagagc tgcatggagt cggcgttgac gacctcgccg tcgagacgct
    29401 gggcgaggaa aacgcccaga tcggactttc ctgccgcggt cggtccgacg acggcgatga
    29461 cgcggggggc ggggggtgcg ctactcactg ccccagtctc gcaaacccga agaccactcc
    29521 tcgaacgagc tacgtgacgg cacgggtgcg gggtcgttgc ctgttgcgag gttccggccg
    29581 ccggtctcgg gagccggtga cccgggcgat gcaaacggac gcaccgggct acgcgggatt
    29641 tcgcccgtac gagtaacgta tggagtggat atgggcgttt ttgcacgact tctccggagg
    29701 tcgaaggcta cgaaggaggc gtcgaccgcc gaggcggagg ccgtgaaggt gacggccgtg
    29761 aaggtgacag ctgagcctgt ggcgaaggtg acggaggagg cgaagggtt
//
